<ForceField>
  <Info>
    <DateGenerated>2019-11-29</DateGenerated>
    <Source Source="parm/frcmod.ions234lm_hfe_tip3p" md5hash="4db3ea62100b95fa9d992ac0875db7f5" sourcePackage="AmberTools" sourcePackageVersion="19.9">parm/frcmod.ions234lm_hfe_tip3p</Source>
    <Source Source="lib/atomic_ions.lib" md5hash="e900cee0c71ec2795d25b3555de486e1" sourcePackage="AmberTools" sourcePackageVersion="19.9">lib/atomic_ions.lib</Source>
    <Reference>Li, P., Roberts, B.P., Chakravorty, D.K., and Merz, K.M. (2013). Rational Design of Particle Mesh Ewald Compatible Lennard-Jones Parameters for +2 Metal Cations in Explicit Solvent. J. Chem. Theory Comput. 9, 2733-2748.</Reference>
    <Reference>Li, P., Song, L.F., and Merz, K.M. (2015). Parameterization of Highly Charged Metal Ions Using the 12-6-4 LJ-Type Nonbonded Model in Explicit Water. J. Phys. Chem. B 119, 883-895.</Reference>
  </Info>
  <AtomTypes>
    <Type element="Be" name="tip3p_HFE_multivalent-Be2+" class="tip3p_HFE_multivalent-Be2+" mass="9.01"/>
    <Type element="Cu" name="tip3p_HFE_multivalent-Cu2+" class="tip3p_HFE_multivalent-Cu2+" mass="63.55"/>
    <Type element="Ni" name="tip3p_HFE_multivalent-Ni2+" class="tip3p_HFE_multivalent-Ni2+" mass="58.69"/>
    <Type element="Pt" name="tip3p_HFE_multivalent-Pt2+" class="tip3p_HFE_multivalent-Pt2+" mass="195.08"/>
    <Type element="Zn" name="tip3p_HFE_multivalent-Zn2+" class="tip3p_HFE_multivalent-Zn2+" mass="65.4"/>
    <Type element="Co" name="tip3p_HFE_multivalent-Co2+" class="tip3p_HFE_multivalent-Co2+" mass="58.93"/>
    <Type element="Pd" name="tip3p_HFE_multivalent-Pd2+" class="tip3p_HFE_multivalent-Pd2+" mass="106.42"/>
    <Type element="Ag" name="tip3p_HFE_multivalent-Ag2+" class="tip3p_HFE_multivalent-Ag2+" mass="107.87"/>
    <Type element="Cr" name="tip3p_HFE_multivalent-Cr2+" class="tip3p_HFE_multivalent-Cr2+" mass="52.0"/>
    <Type element="Fe" name="tip3p_HFE_multivalent-Fe2+" class="tip3p_HFE_multivalent-Fe2+" mass="55.85"/>
    <Type element="Mg" name="tip3p_HFE_multivalent-Mg2+" class="tip3p_HFE_multivalent-Mg2+" mass="24.305"/>
    <Type element="V" name="tip3p_HFE_multivalent-V2+" class="tip3p_HFE_multivalent-V2+" mass="50.94"/>
    <Type element="Mn" name="tip3p_HFE_multivalent-Mn2+" class="tip3p_HFE_multivalent-Mn2+" mass="54.94"/>
    <Type element="Hg" name="tip3p_HFE_multivalent-Hg2+" class="tip3p_HFE_multivalent-Hg2+" mass="200.59"/>
    <Type element="Cd" name="tip3p_HFE_multivalent-Cd2+" class="tip3p_HFE_multivalent-Cd2+" mass="112.41"/>
    <Type element="Yb" name="tip3p_HFE_multivalent-Yb2+" class="tip3p_HFE_multivalent-Yb2+" mass="173.05"/>
    <Type element="Ca" name="tip3p_HFE_multivalent-Ca2+" class="tip3p_HFE_multivalent-Ca2+" mass="40.08"/>
    <Type element="Sn" name="tip3p_HFE_multivalent-Sn2+" class="tip3p_HFE_multivalent-Sn2+" mass="118.71"/>
    <Type element="Pb" name="tip3p_HFE_multivalent-Pb2+" class="tip3p_HFE_multivalent-Pb2+" mass="207.2"/>
    <Type element="Eu" name="tip3p_HFE_multivalent-Eu2+" class="tip3p_HFE_multivalent-Eu2+" mass="151.96"/>
    <Type element="Sr" name="tip3p_HFE_multivalent-Sr2+" class="tip3p_HFE_multivalent-Sr2+" mass="87.62"/>
    <Type element="Sm" name="tip3p_HFE_multivalent-Sm2+" class="tip3p_HFE_multivalent-Sm2+" mass="150.36"/>
    <Type element="Ba" name="tip3p_HFE_multivalent-Ba2+" class="tip3p_HFE_multivalent-Ba2+" mass="137.33"/>
    <Type element="Ra" name="tip3p_HFE_multivalent-Ra2+" class="tip3p_HFE_multivalent-Ra2+" mass="226.03"/>
    <Type element="Al" name="tip3p_HFE_multivalent-Al3+" class="tip3p_HFE_multivalent-Al3+" mass="26.98"/>
    <Type element="Fe" name="tip3p_HFE_multivalent-Fe3+" class="tip3p_HFE_multivalent-Fe3+" mass="55.85"/>
    <Type element="Cr" name="tip3p_HFE_multivalent-Cr3+" class="tip3p_HFE_multivalent-Cr3+" mass="52.0"/>
    <Type element="In" name="tip3p_HFE_multivalent-In3+" class="tip3p_HFE_multivalent-In3+" mass="114.82"/>
    <Type element="Tl" name="tip3p_HFE_multivalent-Tl3+" class="tip3p_HFE_multivalent-Tl3+" mass="204.38"/>
    <Type element="Y" name="tip3p_HFE_multivalent-Y3+" class="tip3p_HFE_multivalent-Y3+" mass="88.91"/>
    <Type element="La" name="tip3p_HFE_multivalent-La3+" class="tip3p_HFE_multivalent-La3+" mass="138.91"/>
    <Type element="Ce" name="tip3p_HFE_multivalent-Ce3+" class="tip3p_HFE_multivalent-Ce3+" mass="140.12"/>
    <Type element="Pr" name="tip3p_HFE_multivalent-Pr3+" class="tip3p_HFE_multivalent-Pr3+" mass="140.91"/>
    <Type element="Nd" name="tip3p_HFE_multivalent-Nd3+" class="tip3p_HFE_multivalent-Nd3+" mass="144.24"/>
    <Type element="Sm" name="tip3p_HFE_multivalent-Sm3+" class="tip3p_HFE_multivalent-Sm3+" mass="150.36"/>
    <Type element="Eu" name="tip3p_HFE_multivalent-Eu3+" class="tip3p_HFE_multivalent-Eu3+" mass="151.96"/>
    <Type element="Gd" name="tip3p_HFE_multivalent-Gd3+" class="tip3p_HFE_multivalent-Gd3+" mass="157.25"/>
    <Type element="Tb" name="tip3p_HFE_multivalent-Tb3+" class="tip3p_HFE_multivalent-Tb3+" mass="158.93"/>
    <Type element="Dy" name="tip3p_HFE_multivalent-Dy3+" class="tip3p_HFE_multivalent-Dy3+" mass="162.5"/>
    <Type element="Er" name="tip3p_HFE_multivalent-Er3+" class="tip3p_HFE_multivalent-Er3+" mass="167.26"/>
    <Type element="Tm" name="tip3p_HFE_multivalent-Tm3+" class="tip3p_HFE_multivalent-Tm3+" mass="168.93"/>
    <Type element="Lu" name="tip3p_HFE_multivalent-Lu3+" class="tip3p_HFE_multivalent-Lu3+" mass="174.97"/>
    <Type element="Hf" name="tip3p_HFE_multivalent-Hf4+" class="tip3p_HFE_multivalent-Hf4+" mass="178.49"/>
    <Type element="Zr" name="tip3p_HFE_multivalent-Zr4+" class="tip3p_HFE_multivalent-Zr4+" mass="91.22"/>
    <Type element="Ce" name="tip3p_HFE_multivalent-Ce4+" class="tip3p_HFE_multivalent-Ce4+" mass="140.12"/>
    <Type element="U" name="tip3p_HFE_multivalent-U4+" class="tip3p_HFE_multivalent-U4+" mass="238.03"/>
    <Type element="Pu" name="tip3p_HFE_multivalent-Pu4+" class="tip3p_HFE_multivalent-Pu4+" mass="244.06"/>
    <Type element="Th" name="tip3p_HFE_multivalent-Th4+" class="tip3p_HFE_multivalent-Th4+" mass="232.04"/>
  </AtomTypes>
  <Residues>
    <Residue name="AL" override="1">
      <Atom name="AL" type="tip3p_HFE_multivalent-Al3+" charge="3.0"/>
    </Residue>
    <Residue name="Ag" override="1">
      <Atom name="Ag" type="tip3p_HFE_multivalent-Ag2+" charge="2.0"/>
    </Residue>
    <Residue name="BA" override="1">
      <Atom name="BA" type="tip3p_HFE_multivalent-Ba2+" charge="2.0"/>
    </Residue>
    <Residue name="Be" override="1">
      <Atom name="Be" type="tip3p_HFE_multivalent-Be2+" charge="2.0"/>
    </Residue>
    <Residue name="CA" override="1">
      <Atom name="CA" type="tip3p_HFE_multivalent-Ca2+" charge="2.0"/>
    </Residue>
    <Residue name="CD" override="1">
      <Atom name="CD" type="tip3p_HFE_multivalent-Cd2+" charge="2.0"/>
    </Residue>
    <Residue name="CE" override="1">
      <Atom name="CE" type="tip3p_HFE_multivalent-Ce3+" charge="3.0"/>
    </Residue>
    <Residue name="CO" override="1">
      <Atom name="CO" type="tip3p_HFE_multivalent-Co2+" charge="2.0"/>
    </Residue>
    <Residue name="CR" override="1">
      <Atom name="CR" type="tip3p_HFE_multivalent-Cr3+" charge="3.0"/>
    </Residue>
    <Residue name="CU" override="1">
      <Atom name="CU" type="tip3p_HFE_multivalent-Cu2+" charge="2.0"/>
    </Residue>
    <Residue name="Ce" override="1">
      <Atom name="Ce" type="tip3p_HFE_multivalent-Ce4+" charge="4.0"/>
    </Residue>
    <Residue name="Cr" override="1">
      <Atom name="Cr" type="tip3p_HFE_multivalent-Cr2+" charge="2.0"/>
    </Residue>
    <Residue name="Dy" override="1">
      <Atom name="Dy" type="tip3p_HFE_multivalent-Dy3+" charge="3.0"/>
    </Residue>
    <Residue name="EU" override="1">
      <Atom name="EU" type="tip3p_HFE_multivalent-Eu2+" charge="2.0"/>
    </Residue>
    <Residue name="EU3" override="1">
      <Atom name="EU3" type="tip3p_HFE_multivalent-Eu3+" charge="3.0"/>
    </Residue>
    <Residue name="Er" override="1">
      <Atom name="Er" type="tip3p_HFE_multivalent-Er3+" charge="3.0"/>
    </Residue>
    <Residue name="FE" override="1">
      <Atom name="FE" type="tip3p_HFE_multivalent-Fe3+" charge="3.0"/>
    </Residue>
    <Residue name="FE2" override="1">
      <Atom name="FE2" type="tip3p_HFE_multivalent-Fe2+" charge="2.0"/>
    </Residue>
    <Residue name="GD3" override="1">
      <Atom name="GD" type="tip3p_HFE_multivalent-Gd3+" charge="3.0"/>
    </Residue>
    <Residue name="HG" override="1">
      <Atom name="HG" type="tip3p_HFE_multivalent-Hg2+" charge="2.0"/>
    </Residue>
    <Residue name="Hf" override="1">
      <Atom name="Hf" type="tip3p_HFE_multivalent-Hf4+" charge="4.0"/>
    </Residue>
    <Residue name="IN" override="1">
      <Atom name="IN" type="tip3p_HFE_multivalent-In3+" charge="3.0"/>
    </Residue>
    <Residue name="LA" override="1">
      <Atom name="LA" type="tip3p_HFE_multivalent-La3+" charge="3.0"/>
    </Residue>
    <Residue name="LU" override="1">
      <Atom name="LU" type="tip3p_HFE_multivalent-Lu3+" charge="3.0"/>
    </Residue>
    <Residue name="MG" override="1">
      <Atom name="MG" type="tip3p_HFE_multivalent-Mg2+" charge="2.0"/>
    </Residue>
    <Residue name="MN" override="1">
      <Atom name="MN" type="tip3p_HFE_multivalent-Mn2+" charge="2.0"/>
    </Residue>
    <Residue name="NI" override="1">
      <Atom name="NI" type="tip3p_HFE_multivalent-Ni2+" charge="2.0"/>
    </Residue>
    <Residue name="Nd" override="1">
      <Atom name="Nd" type="tip3p_HFE_multivalent-Nd3+" charge="3.0"/>
    </Residue>
    <Residue name="PB" override="1">
      <Atom name="PB" type="tip3p_HFE_multivalent-Pb2+" charge="2.0"/>
    </Residue>
    <Residue name="PD" override="1">
      <Atom name="PD" type="tip3p_HFE_multivalent-Pd2+" charge="2.0"/>
    </Residue>
    <Residue name="PR" override="1">
      <Atom name="PR" type="tip3p_HFE_multivalent-Pr3+" charge="3.0"/>
    </Residue>
    <Residue name="PT" override="1">
      <Atom name="PT" type="tip3p_HFE_multivalent-Pt2+" charge="2.0"/>
    </Residue>
    <Residue name="Pu" override="1">
      <Atom name="Pu" type="tip3p_HFE_multivalent-Pu4+" charge="4.0"/>
    </Residue>
    <Residue name="Ra" override="1">
      <Atom name="Ra" type="tip3p_HFE_multivalent-Ra2+" charge="2.0"/>
    </Residue>
    <Residue name="SM" override="1">
      <Atom name="SM" type="tip3p_HFE_multivalent-Sm3+" charge="3.0"/>
    </Residue>
    <Residue name="SR" override="1">
      <Atom name="SR" type="tip3p_HFE_multivalent-Sr2+" charge="2.0"/>
    </Residue>
    <Residue name="Sm" override="1">
      <Atom name="Sm" type="tip3p_HFE_multivalent-Sm2+" charge="2.0"/>
    </Residue>
    <Residue name="Sn" override="1">
      <Atom name="Sn" type="tip3p_HFE_multivalent-Sn2+" charge="2.0"/>
    </Residue>
    <Residue name="TB" override="1">
      <Atom name="TB" type="tip3p_HFE_multivalent-Tb3+" charge="3.0"/>
    </Residue>
    <Residue name="Th" override="1">
      <Atom name="Th" type="tip3p_HFE_multivalent-Th4+" charge="4.0"/>
    </Residue>
    <Residue name="Tl" override="1">
      <Atom name="Tl" type="tip3p_HFE_multivalent-Tl3+" charge="3.0"/>
    </Residue>
    <Residue name="Tm" override="1">
      <Atom name="Tm" type="tip3p_HFE_multivalent-Tm3+" charge="3.0"/>
    </Residue>
    <Residue name="U4+" override="1">
      <Atom name="U" type="tip3p_HFE_multivalent-U4+" charge="4.0"/>
    </Residue>
    <Residue name="V2+" override="1">
      <Atom name="V2+" type="tip3p_HFE_multivalent-V2+" charge="2.0"/>
    </Residue>
    <Residue name="Y" override="1">
      <Atom name="Y" type="tip3p_HFE_multivalent-Y3+" charge="3.0"/>
    </Residue>
    <Residue name="YB2" override="1">
      <Atom name="YB2" type="tip3p_HFE_multivalent-Yb2+" charge="2.0"/>
    </Residue>
    <Residue name="ZN" override="1">
      <Atom name="ZN" type="tip3p_HFE_multivalent-Zn2+" charge="2.0"/>
    </Residue>
    <Residue name="Zr" override="1">
      <Atom name="Zr" type="tip3p_HFE_multivalent-Zr4+" charge="4.0"/>
    </Residue>
  </Residues>
  <NonbondedForce coulomb14scale="0.8333333333333334" lj14scale="0.5">
    <UseAttributeFromResidue name="charge"/>
    <Atom type="tip3p_HFE_multivalent-Be2+" sigma="0.16160902747065756" epsilon="3.3472e-06"/>
    <Atom type="tip3p_HFE_multivalent-Cu2+" sigma="0.20383762671050965" epsilon="0.00168209352"/>
    <Atom type="tip3p_HFE_multivalent-Ni2+" sigma="0.20704486209581485" epsilon="0.00236358344"/>
    <Atom type="tip3p_HFE_multivalent-Pt2+" sigma="0.2090048392757236" epsilon="0.00288846624"/>
    <Atom type="tip3p_HFE_multivalent-Zn2+" sigma="0.20936119876297973" epsilon="0.00299398672"/>
    <Atom type="tip3p_HFE_multivalent-Co2+" sigma="0.21577566953359018" epsilon="0.00554580832"/>
    <Atom type="tip3p_HFE_multivalent-Pd2+" sigma="0.21648838850810248" epsilon="0.00591923032"/>
    <Atom type="tip3p_HFE_multivalent-Ag2+" sigma="0.2250410162022497" epsilon="0.012329536720000001"/>
    <Atom type="tip3p_HFE_multivalent-Cr2+" sigma="0.22682281363853038" epsilon="0.0142138848"/>
    <Atom type="tip3p_HFE_multivalent-Fe2+" sigma="0.22753553261304266" epsilon="0.015031229200000001"/>
    <Atom type="tip3p_HFE_multivalent-Mg2+" sigma="0.22878279081843914" epsilon="0.01655449808"/>
    <Atom type="tip3p_HFE_multivalent-V2+" sigma="0.22985186928020754" epsilon="0.01795869032"/>
    <Atom type="tip3p_HFE_multivalent-Mn2+" sigma="0.23858267671798283" epsilon="0.033437523840000004"/>
    <Atom type="tip3p_HFE_multivalent-Hg2+" sigma="0.23858267671798283" epsilon="0.033437523840000004"/>
    <Atom type="tip3p_HFE_multivalent-Cd2+" sigma="0.23858267671798283" epsilon="0.033437523840000004"/>
    <Atom type="tip3p_HFE_multivalent-Yb2+" sigma="0.2719022887764316" epsilon="0.19966935008"/>
    <Atom type="tip3p_HFE_multivalent-Ca2+" sigma="0.2722586482636877" epsilon="0.20268659984"/>
    <Atom type="tip3p_HFE_multivalent-Sn2+" sigma="0.2749313444181087" epsilon="0.22628971536"/>
    <Atom type="tip3p_HFE_multivalent-Pb2+" sigma="0.2886511846774699" epsilon="0.37512380016"/>
    <Atom type="tip3p_HFE_multivalent-Eu2+" sigma="0.29684745288436104" epsilon="0.48608615792"/>
    <Atom type="tip3p_HFE_multivalent-Sr2+" sigma="0.29791653134612944" epsilon="0.5017316820000001"/>
    <Atom type="tip3p_HFE_multivalent-Sm2+" sigma="0.299341969295154" epsilon="0.52299970712"/>
    <Atom type="tip3p_HFE_multivalent-Ba2+" sigma="0.32820708776290103" epsilon="1.0385202632000001"/>
    <Atom type="tip3p_HFE_multivalent-Ra2+" sigma="0.32820708776290103" epsilon="1.0385202632000001"/>
    <Atom type="tip3p_HFE_multivalent-Al3+" sigma="0.23109912748560402" epsilon="0.01971831336"/>
    <Atom type="tip3p_HFE_multivalent-Fe3+" sigma="0.24695712466850203" epsilon="0.05678093848"/>
    <Atom type="tip3p_HFE_multivalent-Cr3+" sigma="0.23947357543612321" epsilon="0.03548032"/>
    <Atom type="tip3p_HFE_multivalent-In3+" sigma="0.26032060544060714" epsilon="0.11751709584"/>
    <Atom type="tip3p_HFE_multivalent-Tl3+" sigma="0.26958595210926667" epsilon="0.18079185336"/>
    <Atom type="tip3p_HFE_multivalent-Y3+" sigma="0.2854439492921647" epsilon="0.33615222504000003"/>
    <Atom type="tip3p_HFE_multivalent-La3+" sigma="0.3061127995530206" epsilon="0.63014479248"/>
    <Atom type="tip3p_HFE_multivalent-Ce3+" sigma="0.3102109336564662" epsilon="0.69962078192"/>
    <Atom type="tip3p_HFE_multivalent-Pr3+" sigma="0.3087854957074416" epsilon="0.67508049224"/>
    <Atom type="tip3p_HFE_multivalent-Nd3+" sigma="0.2995201490387821" epsilon="0.52569060488"/>
    <Atom type="tip3p_HFE_multivalent-Sm3+" sigma="0.2956001946789646" epsilon="0.46816830344000004"/>
    <Atom type="tip3p_HFE_multivalent-Eu3+" sigma="0.29684745288436104" epsilon="0.48608615792"/>
    <Atom type="tip3p_HFE_multivalent-Gd3+" sigma="0.2891857239083541" epsilon="0.38186547936"/>
    <Atom type="tip3p_HFE_multivalent-Tb3+" sigma="0.29043298211375057" epsilon="0.39786810784"/>
    <Atom type="tip3p_HFE_multivalent-Dy3+" sigma="0.28669120749756116" epsilon="0.35100580160000006"/>
    <Atom type="tip3p_HFE_multivalent-Er3+" sigma="0.2854439492921647" epsilon="0.33615222504000003"/>
    <Atom type="tip3p_HFE_multivalent-Tm3+" sigma="0.2854439492921647" epsilon="0.33615222504000003"/>
    <Atom type="tip3p_HFE_multivalent-Lu3+" sigma="0.28294943288137175" epsilon="0.30760316128000004"/>
    <Atom type="tip3p_HFE_multivalent-Hf4+" sigma="0.26709143569847377" epsilon="0.16186477624"/>
    <Atom type="tip3p_HFE_multivalent-Zr4+" sigma="0.27065503057103507" epsilon="0.18934696184"/>
    <Atom type="tip3p_HFE_multivalent-Ce4+" sigma="0.30005468826966625" epsilon="0.53380618416"/>
    <Atom type="tip3p_HFE_multivalent-U4+" sigma="0.30005468826966625" epsilon="0.53380618416"/>
    <Atom type="tip3p_HFE_multivalent-Pu4+" sigma="0.29613473390984874" epsilon="0.47580293192"/>
    <Atom type="tip3p_HFE_multivalent-Th4+" sigma="0.3043310021167399" epsilon="0.6009964544"/>
  </NonbondedForce>
</ForceField>
