/* Generated by Cython 0.19.1 on Wed Jun 28 05:32:00 2017 */

#define PY_SSIZE_T_CLEAN
#ifndef CYTHON_USE_PYLONG_INTERNALS
#ifdef PYLONG_BITS_IN_DIGIT
#define CYTHON_USE_PYLONG_INTERNALS 0
#else
#include "pyconfig.h"
#ifdef PYLONG_BITS_IN_DIGIT
#define CYTHON_USE_PYLONG_INTERNALS 1
#else
#define CYTHON_USE_PYLONG_INTERNALS 0
#endif
#endif
#endif
#include "Python.h"
#ifndef Py_PYTHON_H
    #error Python headers needed to compile C extensions, please install development version of Python.
#elif PY_VERSION_HEX < 0x02040000
    #error Cython requires Python 2.4+.
#else
#include <stddef.h> /* For offsetof */
#ifndef offsetof
#define offsetof(type, member) ( (size_t) & ((type*)0) -> member )
#endif
#if !defined(WIN32) && !defined(MS_WINDOWS)
  #ifndef __stdcall
    #define __stdcall
  #endif
  #ifndef __cdecl
    #define __cdecl
  #endif
  #ifndef __fastcall
    #define __fastcall
  #endif
#endif
#ifndef DL_IMPORT
  #define DL_IMPORT(t) t
#endif
#ifndef DL_EXPORT
  #define DL_EXPORT(t) t
#endif
#ifndef PY_LONG_LONG
  #define PY_LONG_LONG LONG_LONG
#endif
#ifndef Py_HUGE_VAL
  #define Py_HUGE_VAL HUGE_VAL
#endif
#ifdef PYPY_VERSION
#define CYTHON_COMPILING_IN_PYPY 1
#define CYTHON_COMPILING_IN_CPYTHON 0
#else
#define CYTHON_COMPILING_IN_PYPY 0
#define CYTHON_COMPILING_IN_CPYTHON 1
#endif
#if PY_VERSION_HEX < 0x02050000
  typedef int Py_ssize_t;
  #define PY_SSIZE_T_MAX INT_MAX
  #define PY_SSIZE_T_MIN INT_MIN
  #define PY_FORMAT_SIZE_T ""
  #define CYTHON_FORMAT_SSIZE_T ""
  #define PyInt_FromSsize_t(z) PyInt_FromLong(z)
  #define PyInt_AsSsize_t(o)   __Pyx_PyInt_AsInt(o)
  #define PyNumber_Index(o)    ((PyNumber_Check(o) && !PyFloat_Check(o)) ? PyNumber_Int(o) : \
                                (PyErr_Format(PyExc_TypeError, \
                                              "expected index value, got %.200s", Py_TYPE(o)->tp_name), \
                                 (PyObject*)0))
  #define __Pyx_PyIndex_Check(o) (PyNumber_Check(o) && !PyFloat_Check(o) && \
                                  !PyComplex_Check(o))
  #define PyIndex_Check __Pyx_PyIndex_Check
  #define PyErr_WarnEx(category, message, stacklevel) PyErr_Warn(category, message)
  #define __PYX_BUILD_PY_SSIZE_T "i"
#else
  #define __PYX_BUILD_PY_SSIZE_T "n"
  #define CYTHON_FORMAT_SSIZE_T "z"
  #define __Pyx_PyIndex_Check PyIndex_Check
#endif
#if PY_VERSION_HEX < 0x02060000
  #define Py_REFCNT(ob) (((PyObject*)(ob))->ob_refcnt)
  #define Py_TYPE(ob)   (((PyObject*)(ob))->ob_type)
  #define Py_SIZE(ob)   (((PyVarObject*)(ob))->ob_size)
  #define PyVarObject_HEAD_INIT(type, size) \
          PyObject_HEAD_INIT(type) size,
  #define PyType_Modified(t)
  typedef struct {
     void *buf;
     PyObject *obj;
     Py_ssize_t len;
     Py_ssize_t itemsize;
     int readonly;
     int ndim;
     char *format;
     Py_ssize_t *shape;
     Py_ssize_t *strides;
     Py_ssize_t *suboffsets;
     void *internal;
  } Py_buffer;
  #define PyBUF_SIMPLE 0
  #define PyBUF_WRITABLE 0x0001
  #define PyBUF_FORMAT 0x0004
  #define PyBUF_ND 0x0008
  #define PyBUF_STRIDES (0x0010 | PyBUF_ND)
  #define PyBUF_C_CONTIGUOUS (0x0020 | PyBUF_STRIDES)
  #define PyBUF_F_CONTIGUOUS (0x0040 | PyBUF_STRIDES)
  #define PyBUF_ANY_CONTIGUOUS (0x0080 | PyBUF_STRIDES)
  #define PyBUF_INDIRECT (0x0100 | PyBUF_STRIDES)
  #define PyBUF_RECORDS (PyBUF_STRIDES | PyBUF_FORMAT | PyBUF_WRITABLE)
  #define PyBUF_FULL (PyBUF_INDIRECT | PyBUF_FORMAT | PyBUF_WRITABLE)
  typedef int (*getbufferproc)(PyObject *, Py_buffer *, int);
  typedef void (*releasebufferproc)(PyObject *, Py_buffer *);
#endif
#if PY_MAJOR_VERSION < 3
  #define __Pyx_BUILTIN_MODULE_NAME "__builtin__"
  #define __Pyx_PyCode_New(a, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos) \
          PyCode_New(a, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)
#else
  #define __Pyx_BUILTIN_MODULE_NAME "builtins"
  #define __Pyx_PyCode_New(a, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos) \
          PyCode_New(a, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)
#endif
#if PY_MAJOR_VERSION < 3 && PY_MINOR_VERSION < 6
  #define PyUnicode_FromString(s) PyUnicode_Decode(s, strlen(s), "UTF-8", "strict")
#endif
#if PY_MAJOR_VERSION >= 3
  #define Py_TPFLAGS_CHECKTYPES 0
  #define Py_TPFLAGS_HAVE_INDEX 0
#endif
#if (PY_VERSION_HEX < 0x02060000) || (PY_MAJOR_VERSION >= 3)
  #define Py_TPFLAGS_HAVE_NEWBUFFER 0
#endif
#if PY_VERSION_HEX < 0x02060000
  #define Py_TPFLAGS_HAVE_VERSION_TAG 0
#endif
#if PY_VERSION_HEX > 0x03030000 && defined(PyUnicode_KIND)
  #define CYTHON_PEP393_ENABLED 1
  #define __Pyx_PyUnicode_READY(op)       (likely(PyUnicode_IS_READY(op)) ? \
                                              0 : _PyUnicode_Ready((PyObject *)(op)))
  #define __Pyx_PyUnicode_GET_LENGTH(u)   PyUnicode_GET_LENGTH(u)
  #define __Pyx_PyUnicode_READ_CHAR(u, i) PyUnicode_READ_CHAR(u, i)
  #define __Pyx_PyUnicode_READ(k, d, i)   PyUnicode_READ(k, d, i)
#else
  #define CYTHON_PEP393_ENABLED 0
  #define __Pyx_PyUnicode_READY(op)       (0)
  #define __Pyx_PyUnicode_GET_LENGTH(u)   PyUnicode_GET_SIZE(u)
  #define __Pyx_PyUnicode_READ_CHAR(u, i) ((Py_UCS4)(PyUnicode_AS_UNICODE(u)[i]))
  #define __Pyx_PyUnicode_READ(k, d, i)   ((k=k), (Py_UCS4)(((Py_UNICODE*)d)[i]))
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyBaseString_Type            PyUnicode_Type
  #define PyStringObject               PyUnicodeObject
  #define PyString_Type                PyUnicode_Type
  #define PyString_Check               PyUnicode_Check
  #define PyString_CheckExact          PyUnicode_CheckExact
#endif
#if PY_VERSION_HEX < 0x02060000
  #define PyBytesObject                PyStringObject
  #define PyBytes_Type                 PyString_Type
  #define PyBytes_Check                PyString_Check
  #define PyBytes_CheckExact           PyString_CheckExact
  #define PyBytes_FromString           PyString_FromString
  #define PyBytes_FromStringAndSize    PyString_FromStringAndSize
  #define PyBytes_FromFormat           PyString_FromFormat
  #define PyBytes_DecodeEscape         PyString_DecodeEscape
  #define PyBytes_AsString             PyString_AsString
  #define PyBytes_AsStringAndSize      PyString_AsStringAndSize
  #define PyBytes_Size                 PyString_Size
  #define PyBytes_AS_STRING            PyString_AS_STRING
  #define PyBytes_GET_SIZE             PyString_GET_SIZE
  #define PyBytes_Repr                 PyString_Repr
  #define PyBytes_Concat               PyString_Concat
  #define PyBytes_ConcatAndDel         PyString_ConcatAndDel
#endif
#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyBaseString_Check(obj) PyUnicode_Check(obj)
  #define __Pyx_PyBaseString_CheckExact(obj) PyUnicode_CheckExact(obj)
#else
  #define __Pyx_PyBaseString_Check(obj) (PyString_CheckExact(obj) || PyUnicode_CheckExact(obj) || \
                                         PyString_Check(obj) || PyUnicode_Check(obj))
  #define __Pyx_PyBaseString_CheckExact(obj) (Py_TYPE(obj) == &PyBaseString_Type)
#endif
#if PY_VERSION_HEX < 0x02060000
  #define PySet_Check(obj)             PyObject_TypeCheck(obj, &PySet_Type)
  #define PyFrozenSet_Check(obj)       PyObject_TypeCheck(obj, &PyFrozenSet_Type)
#endif
#ifndef PySet_CheckExact
  #define PySet_CheckExact(obj)        (Py_TYPE(obj) == &PySet_Type)
#endif
#define __Pyx_TypeCheck(obj, type) PyObject_TypeCheck(obj, (PyTypeObject *)type)
#if PY_MAJOR_VERSION >= 3
  #define PyIntObject                  PyLongObject
  #define PyInt_Type                   PyLong_Type
  #define PyInt_Check(op)              PyLong_Check(op)
  #define PyInt_CheckExact(op)         PyLong_CheckExact(op)
  #define PyInt_FromString             PyLong_FromString
  #define PyInt_FromUnicode            PyLong_FromUnicode
  #define PyInt_FromLong               PyLong_FromLong
  #define PyInt_FromSize_t             PyLong_FromSize_t
  #define PyInt_FromSsize_t            PyLong_FromSsize_t
  #define PyInt_AsLong                 PyLong_AsLong
  #define PyInt_AS_LONG                PyLong_AS_LONG
  #define PyInt_AsSsize_t              PyLong_AsSsize_t
  #define PyInt_AsUnsignedLongMask     PyLong_AsUnsignedLongMask
  #define PyInt_AsUnsignedLongLongMask PyLong_AsUnsignedLongLongMask
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyBoolObject                 PyLongObject
#endif
#if PY_VERSION_HEX < 0x03020000
  typedef long Py_hash_t;
  #define __Pyx_PyInt_FromHash_t PyInt_FromLong
  #define __Pyx_PyInt_AsHash_t   PyInt_AsLong
#else
  #define __Pyx_PyInt_FromHash_t PyInt_FromSsize_t
  #define __Pyx_PyInt_AsHash_t   PyInt_AsSsize_t
#endif
#if (PY_MAJOR_VERSION < 3) || (PY_VERSION_HEX >= 0x03010300)
  #define __Pyx_PySequence_GetSlice(obj, a, b) PySequence_GetSlice(obj, a, b)
  #define __Pyx_PySequence_SetSlice(obj, a, b, value) PySequence_SetSlice(obj, a, b, value)
  #define __Pyx_PySequence_DelSlice(obj, a, b) PySequence_DelSlice(obj, a, b)
#else
  #define __Pyx_PySequence_GetSlice(obj, a, b) (unlikely(!(obj)) ? \
        (PyErr_SetString(PyExc_SystemError, "null argument to internal routine"), (PyObject*)0) : \
        (likely((obj)->ob_type->tp_as_mapping) ? (PySequence_GetSlice(obj, a, b)) : \
            (PyErr_Format(PyExc_TypeError, "'%.200s' object is unsliceable", (obj)->ob_type->tp_name), (PyObject*)0)))
  #define __Pyx_PySequence_SetSlice(obj, a, b, value) (unlikely(!(obj)) ? \
        (PyErr_SetString(PyExc_SystemError, "null argument to internal routine"), -1) : \
        (likely((obj)->ob_type->tp_as_mapping) ? (PySequence_SetSlice(obj, a, b, value)) : \
            (PyErr_Format(PyExc_TypeError, "'%.200s' object doesn't support slice assignment", (obj)->ob_type->tp_name), -1)))
  #define __Pyx_PySequence_DelSlice(obj, a, b) (unlikely(!(obj)) ? \
        (PyErr_SetString(PyExc_SystemError, "null argument to internal routine"), -1) : \
        (likely((obj)->ob_type->tp_as_mapping) ? (PySequence_DelSlice(obj, a, b)) : \
            (PyErr_Format(PyExc_TypeError, "'%.200s' object doesn't support slice deletion", (obj)->ob_type->tp_name), -1)))
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyMethod_New(func, self, klass) ((self) ? PyMethod_New(func, self) : PyInstanceMethod_New(func))
#endif
#if PY_VERSION_HEX < 0x02050000
  #define __Pyx_GetAttrString(o,n)   PyObject_GetAttrString((o),((char *)(n)))
  #define __Pyx_SetAttrString(o,n,a) PyObject_SetAttrString((o),((char *)(n)),(a))
  #define __Pyx_DelAttrString(o,n)   PyObject_DelAttrString((o),((char *)(n)))
#else
  #define __Pyx_GetAttrString(o,n)   PyObject_GetAttrString((o),(n))
  #define __Pyx_SetAttrString(o,n,a) PyObject_SetAttrString((o),(n),(a))
  #define __Pyx_DelAttrString(o,n)   PyObject_DelAttrString((o),(n))
#endif
#if PY_VERSION_HEX < 0x02050000
  #define __Pyx_NAMESTR(n) ((char *)(n))
  #define __Pyx_DOCSTR(n)  ((char *)(n))
#else
  #define __Pyx_NAMESTR(n) (n)
  #define __Pyx_DOCSTR(n)  (n)
#endif
#ifndef CYTHON_INLINE
  #if defined(__GNUC__)
    #define CYTHON_INLINE __inline__
  #elif defined(_MSC_VER)
    #define CYTHON_INLINE __inline
  #elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define CYTHON_INLINE inline
  #else
    #define CYTHON_INLINE
  #endif
#endif
#ifndef CYTHON_RESTRICT
  #if defined(__GNUC__)
    #define CYTHON_RESTRICT __restrict__
  #elif defined(_MSC_VER)
    #define CYTHON_RESTRICT __restrict
  #elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define CYTHON_RESTRICT restrict
  #else
    #define CYTHON_RESTRICT
  #endif
#endif
#ifdef NAN
#define __PYX_NAN() ((float) NAN)
#else
static CYTHON_INLINE float __PYX_NAN() {
  /* Initialize NaN. The sign is irrelevant, an exponent with all bits 1 and
   a nonzero mantissa means NaN. If the first bit in the mantissa is 1, it is
   a quiet NaN. */
  float value;
  memset(&value, 0xFF, sizeof(value));
  return value;
}
#endif


#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyNumber_Divide(x,y)         PyNumber_TrueDivide(x,y)
  #define __Pyx_PyNumber_InPlaceDivide(x,y)  PyNumber_InPlaceTrueDivide(x,y)
#else
  #define __Pyx_PyNumber_Divide(x,y)         PyNumber_Divide(x,y)
  #define __Pyx_PyNumber_InPlaceDivide(x,y)  PyNumber_InPlaceDivide(x,y)
#endif

#ifndef __PYX_EXTERN_C
  #ifdef __cplusplus
    #define __PYX_EXTERN_C extern "C"
  #else
    #define __PYX_EXTERN_C extern
  #endif
#endif

#if defined(WIN32) || defined(MS_WINDOWS)
#define _USE_MATH_DEFINES
#endif
#include <math.h>
#define __PYX_HAVE__variant
#define __PYX_HAVE_API__variant
#include "string.h"
#include "stdio.h"
#include "pythread.h"
#include "stdlib.h"
#include "math.h"
#include "ctype.h"
#include "stdint.h"
#include "htslib/bgzf.h"
#include "htslib/hts.h"
#include "htslib/sam.h"
#ifdef _OPENMP
#include <omp.h>
#endif /* _OPENMP */

#ifdef PYREX_WITHOUT_ASSERTIONS
#define CYTHON_WITHOUT_ASSERTIONS
#endif

#ifndef CYTHON_UNUSED
# if defined(__GNUC__)
#   if !(defined(__cplusplus)) || (__GNUC__ > 3 || (__GNUC__ == 3 && __GNUC_MINOR__ >= 4))
#     define CYTHON_UNUSED __attribute__ ((__unused__))
#   else
#     define CYTHON_UNUSED
#   endif
# elif defined(__ICC) || (defined(__INTEL_COMPILER) && !defined(_MSC_VER))
#   define CYTHON_UNUSED __attribute__ ((__unused__))
# else
#   define CYTHON_UNUSED
# endif
#endif
typedef struct {PyObject **p; char *s; const Py_ssize_t n; const char* encoding;
                const char is_unicode; const char is_str; const char intern; } __Pyx_StringTabEntry; /*proto*/

#define __PYX_DEFAULT_STRING_ENCODING_IS_ASCII 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT 0
#define __PYX_DEFAULT_STRING_ENCODING ""
#define __Pyx_PyObject_FromString __Pyx_PyBytes_FromString
#define __Pyx_PyObject_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
static CYTHON_INLINE char* __Pyx_PyObject_AsString(PyObject*);
static CYTHON_INLINE char* __Pyx_PyObject_AsStringAndSize(PyObject*, Py_ssize_t* length);
#define __Pyx_PyBytes_FromString        PyBytes_FromString
#define __Pyx_PyBytes_FromStringAndSize PyBytes_FromStringAndSize
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(char*);
#if PY_MAJOR_VERSION < 3
    #define __Pyx_PyStr_FromString        __Pyx_PyBytes_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#else
    #define __Pyx_PyStr_FromString        __Pyx_PyUnicode_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyUnicode_FromStringAndSize
#endif
#define __Pyx_PyObject_AsUString(s)    ((unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_FromUString(s)  __Pyx_PyObject_FromString((char*)s)
#define __Pyx_PyBytes_FromUString(s)   __Pyx_PyBytes_FromString((char*)s)
#define __Pyx_PyStr_FromUString(s)     __Pyx_PyStr_FromString((char*)s)
#define __Pyx_PyUnicode_FromUString(s) __Pyx_PyUnicode_FromString((char*)s)
#if PY_MAJOR_VERSION < 3
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const Py_UNICODE *u)
{
    const Py_UNICODE *u_end = u;
    while (*u_end++) ;
    return u_end - u - 1;
}
#else
#define __Pyx_Py_UNICODE_strlen Py_UNICODE_strlen
#endif
#define __Pyx_PyUnicode_FromUnicode(u)       PyUnicode_FromUnicode(u, __Pyx_Py_UNICODE_strlen(u))
#define __Pyx_PyUnicode_FromUnicodeAndLength PyUnicode_FromUnicode
#define __Pyx_PyUnicode_AsUnicode            PyUnicode_AsUnicode
#define __Pyx_Owned_Py_None(b) (Py_INCREF(Py_None), Py_None)
#define __Pyx_PyBool_FromLong(b) ((b) ? (Py_INCREF(Py_True), Py_True) : (Py_INCREF(Py_False), Py_False))
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject*);
static CYTHON_INLINE PyObject* __Pyx_PyNumber_Int(PyObject* x);
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject*);
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t);
static CYTHON_INLINE size_t __Pyx_PyInt_AsSize_t(PyObject*);
#if CYTHON_COMPILING_IN_CPYTHON
#define __pyx_PyFloat_AsDouble(x) (PyFloat_CheckExact(x) ? PyFloat_AS_DOUBLE(x) : PyFloat_AsDouble(x))
#else
#define __pyx_PyFloat_AsDouble(x) PyFloat_AsDouble(x)
#endif
#define __pyx_PyFloat_AsFloat(x) ((float) __pyx_PyFloat_AsDouble(x))
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
static int __Pyx_sys_getdefaultencoding_not_ascii;
static int __Pyx_init_sys_getdefaultencoding_params() {
    PyObject* sys = NULL;
    PyObject* default_encoding = NULL;
    PyObject* ascii_chars_u = NULL;
    PyObject* ascii_chars_b = NULL;
    sys = PyImport_ImportModule("sys");
    if (sys == NULL) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    if (default_encoding == NULL) goto bad;
    if (strcmp(PyBytes_AsString(default_encoding), "ascii") == 0) {
        __Pyx_sys_getdefaultencoding_not_ascii = 0;
    } else {
        const char* default_encoding_c = PyBytes_AS_STRING(default_encoding);
        char ascii_chars[128];
        int c;
        for (c = 0; c < 128; c++) {
            ascii_chars[c] = c;
        }
        __Pyx_sys_getdefaultencoding_not_ascii = 1;
        ascii_chars_u = PyUnicode_DecodeASCII(ascii_chars, 128, NULL);
        if (ascii_chars_u == NULL) goto bad;
        ascii_chars_b = PyUnicode_AsEncodedString(ascii_chars_u, default_encoding_c, NULL);
        if (ascii_chars_b == NULL || strncmp(ascii_chars, PyBytes_AS_STRING(ascii_chars_b), 128) != 0) {
            PyErr_Format(
                PyExc_ValueError,
                "This module compiled with c_string_encoding=ascii, but default encoding '%s' is not a superset of ascii.",
                default_encoding_c);
            goto bad;
        }
    }
    Py_XDECREF(sys);
    Py_XDECREF(default_encoding);
    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
    return 0;
bad:
    Py_XDECREF(sys);
    Py_XDECREF(default_encoding);
    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
    return -1;
}
#endif
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT && PY_MAJOR_VERSION >= 3
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_DecodeUTF8(c_str, size, NULL)
#else
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_Decode(c_str, size, __PYX_DEFAULT_STRING_ENCODING, NULL)
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
static char* __PYX_DEFAULT_STRING_ENCODING;
static int __Pyx_init_sys_getdefaultencoding_params() {
    PyObject* sys = NULL;
    PyObject* default_encoding = NULL;
    char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (sys == NULL) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    if (default_encoding == NULL) goto bad;
    default_encoding_c = PyBytes_AS_STRING(default_encoding);
    __PYX_DEFAULT_STRING_ENCODING = (char*) malloc(strlen(default_encoding_c));
    strcpy(__PYX_DEFAULT_STRING_ENCODING, default_encoding_c);
    Py_DECREF(sys);
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(sys);
    Py_XDECREF(default_encoding);
    return -1;
}
#endif
#endif


#ifdef __GNUC__
  /* Test for GCC > 2.95 */
  #if __GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95))
    #define likely(x)   __builtin_expect(!!(x), 1)
    #define unlikely(x) __builtin_expect(!!(x), 0)
  #else /* __GNUC__ > 2 ... */
    #define likely(x)   (x)
    #define unlikely(x) (x)
  #endif /* __GNUC__ > 2 ... */
#else /* __GNUC__ */
  #define likely(x)   (x)
  #define unlikely(x) (x)
#endif /* __GNUC__ */

static PyObject *__pyx_m;
static PyObject *__pyx_d;
static PyObject *__pyx_b;
static PyObject *__pyx_empty_tuple;
static PyObject *__pyx_empty_bytes;
static int __pyx_lineno;
static int __pyx_clineno = 0;
static const char * __pyx_cfilenm= __FILE__;
static const char *__pyx_filename;


static const char *__pyx_f[] = {
  "variant.pyx",
  "variant.pxd",
  "fastafile.pxd",
  "type.pxd",
  "bool.pxd",
  "complex.pxd",
  "htslibWrapper.pxd",
};

/*--- Type declarations ---*/
struct __pyx_obj_7variant_VariantCandidateGenerator;
struct __pyx_obj_9fastafile_FastaFile;
struct __pyx_obj_13htslibWrapper_Samfile;
struct __pyx_obj_9fastafile_FastaIndex;
struct __pyx_obj_13htslibWrapper_ReadIterator;
struct __pyx_obj_7variant_Variant;
struct __pyx_t_13htslibWrapper_cAlignedRead;
typedef struct __pyx_t_13htslibWrapper_cAlignedRead __pyx_t_13htslibWrapper_cAlignedRead;
struct __pyx_opt_args_13htslibWrapper_7Samfile__open;

/* "htslibWrapper.pxd":187
 *     int bam_cigar_oplen(uint32_t c)
 * 
 * ctypedef struct cAlignedRead:             # <<<<<<<<<<<<<<
 *     char* seq
 *     char* qual
 */
struct __pyx_t_13htslibWrapper_cAlignedRead {
  char *seq;
  char *qual;
  short *cigarOps;
  short *hash;
  short mateChromID;
  short cigarLen;
  short chromID;
  short rlen;
  int pos;
  int end;
  int insertSize;
  int matePos;
  int bitFlag;
  unsigned char mapq;
};

/* "htslibWrapper.pxd":211
 *     cdef _hasIndex(self)
 *     cdef void openBAMFile(self, mode)
 *     cpdef _open(self, mode, loadIndex=*)             # <<<<<<<<<<<<<<
 *     cdef char* getrname(self, int tid)
 *     cpdef ReadIterator fetch(self, const char *region)
 */
struct __pyx_opt_args_13htslibWrapper_7Samfile__open {
  int __pyx_n;
  PyObject *loadIndex;
};

/* "variant.pxd":44
 * 
 * @cython.final
 * cdef class VariantCandidateGenerator:             # <<<<<<<<<<<<<<
 *     cdef int CIGAR_M
 *     cdef int CIGAR_I
 */
struct __pyx_obj_7variant_VariantCandidateGenerator {
  PyObject_HEAD
  struct __pyx_vtabstruct_7variant_VariantCandidateGenerator *__pyx_vtab;
  int CIGAR_M;
  int CIGAR_I;
  int CIGAR_D;
  int CIGAR_N;
  int CIGAR_S;
  int CIGAR_H;
  int CIGAR_P;
  int CIGAR_EQ;
  int CIGAR_X;
  int minMapQual;
  int minBaseQual;
  int minFlank;
  int refId;
  int maxCoverage;
  int verbosity;
  int genSNPs;
  int genIndels;
  int maxReadLength;
  long rStart;
  long rEnd;
  long refSeqStart;
  long refSeqEnd;
  char *refSeq;
  PyObject *variantHeap;
  PyObject *pyRefSeq;
  PyObject *rname;
  struct __pyx_obj_9fastafile_FastaFile *refFile;
  PyObject *options;
  int qualBinSize;
};


/* "fastafile.pxd":5
 *     cdef dict getRefs(self, int parseNCBI)
 * 
 * cdef class FastaFile(object):             # <<<<<<<<<<<<<<
 *     cdef object theFile
 *     cdef FastaIndex theIndex
 */
struct __pyx_obj_9fastafile_FastaFile {
  PyObject_HEAD
  struct __pyx_vtabstruct_9fastafile_FastaFile *__pyx_vtab;
  PyObject *theFile;
  struct __pyx_obj_9fastafile_FastaIndex *theIndex;
  PyObject *refs;
  PyObject *cache;
  PyObject *cacheRefName;
  PY_LONG_LONG cacheStartPos;
  PY_LONG_LONG cacheEndPos;
};


/* "htslibWrapper.pxd":203
 *     unsigned char mapq
 * 
 * cdef class Samfile:             # <<<<<<<<<<<<<<
 *     cdef void clearHeader(self)
 *     cdef void clearIndex(self)
 */
struct __pyx_obj_13htslibWrapper_Samfile {
  PyObject_HEAD
  struct __pyx_vtabstruct_13htslibWrapper_Samfile *__pyx_vtab;
  char *filename;
  samFile *samfile;
  bam_hdr_t *theHeader;
  hts_idx_t *index;
  PyObject *lock;
};


/* "fastafile.pxd":1
 * cdef class FastaIndex:             # <<<<<<<<<<<<<<
 *     cdef object theFile
 *     cdef dict getRefs(self, int parseNCBI)
 */
struct __pyx_obj_9fastafile_FastaIndex {
  PyObject_HEAD
  struct __pyx_vtabstruct_9fastafile_FastaIndex *__pyx_vtab;
  PyObject *theFile;
};


/* "htslibWrapper.pxd":222
 *     cdef object lock
 * 
 * cdef class ReadIterator:             # <<<<<<<<<<<<<<
 *     cdef cAlignedRead* get(self, int storeRgID, char** rgID)
 *     cdef int cnext(self) nogil
 */
struct __pyx_obj_13htslibWrapper_ReadIterator {
  PyObject_HEAD
  struct __pyx_vtabstruct_13htslibWrapper_ReadIterator *__pyx_vtab;
  samFile *theSamfile;
  hts_itr_t *theIterator;
  bam1_t *b;
};


/* "variant.pxd":17
 * 
 * @cython.final
 * cdef class Variant:             # <<<<<<<<<<<<<<
 *     cdef:
 *         public bytes refName
 */
struct __pyx_obj_7variant_Variant {
  PyObject_HEAD
  struct __pyx_vtabstruct_7variant_Variant *__pyx_vtab;
  PyObject *refName;
  PyObject *added;
  PyObject *removed;
  PyObject *bamAdded;
  PyObject *bamRemoved;
  int refPos;
  int bamMinPos;
  int bamMaxPos;
  int minRefPos;
  int maxRefPos;
  int nSupportingReads;
  int varSource;
  int hashValue;
  int nAdded;
  int nRemoved;
  int varType;
};



/* "fastafile.pxd":1
 * cdef class FastaIndex:             # <<<<<<<<<<<<<<
 *     cdef object theFile
 *     cdef dict getRefs(self, int parseNCBI)
 */

struct __pyx_vtabstruct_9fastafile_FastaIndex {
  PyObject *(*getRefs)(struct __pyx_obj_9fastafile_FastaIndex *, int);
};
static struct __pyx_vtabstruct_9fastafile_FastaIndex *__pyx_vtabptr_9fastafile_FastaIndex;


/* "fastafile.pxd":5
 *     cdef dict getRefs(self, int parseNCBI)
 * 
 * cdef class FastaFile(object):             # <<<<<<<<<<<<<<
 *     cdef object theFile
 *     cdef FastaIndex theIndex
 */

struct __pyx_vtabstruct_9fastafile_FastaFile {
  PyObject *(*getCharacter)(struct __pyx_obj_9fastafile_FastaFile *, PyObject *, PY_LONG_LONG);
  PyObject *(*getSequence)(struct __pyx_obj_9fastafile_FastaFile *, PyObject *, PY_LONG_LONG, PY_LONG_LONG);
  void (*setCacheSequence)(struct __pyx_obj_9fastafile_FastaFile *, PyObject *, PY_LONG_LONG, PY_LONG_LONG);
};
static struct __pyx_vtabstruct_9fastafile_FastaFile *__pyx_vtabptr_9fastafile_FastaFile;


/* "variant.pyx":100
 * 
 * @cython.final
 * cdef class Variant(object):             # <<<<<<<<<<<<<<
 *     """
 *     Class to encapsulate information for all common variant types. The basic
 */

struct __pyx_vtabstruct_7variant_Variant {
  double (*indelPrior)(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_9fastafile_FastaFile *, int);
  double (*calculatePrior)(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_9fastafile_FastaFile *);
  void (*addVariant)(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_7variant_Variant *);
  int (*overlaps)(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_7variant_Variant *);
};
static struct __pyx_vtabstruct_7variant_Variant *__pyx_vtabptr_7variant_Variant;
static double __pyx_f_7variant_7Variant_indelPrior(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_9fastafile_FastaFile *, int);
static double __pyx_f_7variant_7Variant_calculatePrior(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_9fastafile_FastaFile *);
static void __pyx_f_7variant_7Variant_addVariant(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_7variant_Variant *);
static int __pyx_f_7variant_7Variant_overlaps(struct __pyx_obj_7variant_Variant *, struct __pyx_obj_7variant_Variant *);


/* "htslibWrapper.pxd":203
 *     unsigned char mapq
 * 
 * cdef class Samfile:             # <<<<<<<<<<<<<<
 *     cdef void clearHeader(self)
 *     cdef void clearIndex(self)
 */

struct __pyx_vtabstruct_13htslibWrapper_Samfile {
  void (*clearHeader)(struct __pyx_obj_13htslibWrapper_Samfile *);
  void (*clearIndex)(struct __pyx_obj_13htslibWrapper_Samfile *);
  int (*_isBam)(struct __pyx_obj_13htslibWrapper_Samfile *);
  int (*_isCram)(struct __pyx_obj_13htslibWrapper_Samfile *);
  int (*_isOpen)(struct __pyx_obj_13htslibWrapper_Samfile *);
  PyObject *(*_hasIndex)(struct __pyx_obj_13htslibWrapper_Samfile *);
  void (*openBAMFile)(struct __pyx_obj_13htslibWrapper_Samfile *, PyObject *);
  PyObject *(*_open)(struct __pyx_obj_13htslibWrapper_Samfile *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_13htslibWrapper_7Samfile__open *__pyx_optional_args);
  char *(*getrname)(struct __pyx_obj_13htslibWrapper_Samfile *, int);
  struct __pyx_obj_13htslibWrapper_ReadIterator *(*fetch)(struct __pyx_obj_13htslibWrapper_Samfile *, char const *, int __pyx_skip_dispatch);
  PyObject *(*close)(struct __pyx_obj_13htslibWrapper_Samfile *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_13htslibWrapper_Samfile *__pyx_vtabptr_13htslibWrapper_Samfile;


/* "htslibWrapper.pxd":222
 *     cdef object lock
 * 
 * cdef class ReadIterator:             # <<<<<<<<<<<<<<
 *     cdef cAlignedRead* get(self, int storeRgID, char** rgID)
 *     cdef int cnext(self) nogil
 */

struct __pyx_vtabstruct_13htslibWrapper_ReadIterator {
  __pyx_t_13htslibWrapper_cAlignedRead *(*get)(struct __pyx_obj_13htslibWrapper_ReadIterator *, int, char **);
  int (*cnext)(struct __pyx_obj_13htslibWrapper_ReadIterator *);
  char (*_getBase)(struct __pyx_obj_13htslibWrapper_ReadIterator *, uint8_t *, int);
};
static struct __pyx_vtabstruct_13htslibWrapper_ReadIterator *__pyx_vtabptr_13htslibWrapper_ReadIterator;


/* "variant.pyx":459
 * 
 * @cython.final
 * cdef class VariantCandidateGenerator(object):             # <<<<<<<<<<<<<<
 *     """
 *     A class to generate variant candidates from a bunch of reads.
 */

struct __pyx_vtabstruct_7variant_VariantCandidateGenerator {
  void (*addVariantToList)(struct __pyx_obj_7variant_VariantCandidateGenerator *, struct __pyx_obj_7variant_Variant *);
  void (*getSnpCandidatesFromReadSegment)(struct __pyx_obj_7variant_VariantCandidateGenerator *, __pyx_t_13htslibWrapper_cAlignedRead *, char *, char *, int, int, int, int, int);
  void (*getVariantCandidatesFromSingleRead)(struct __pyx_obj_7variant_VariantCandidateGenerator *, __pyx_t_13htslibWrapper_cAlignedRead *);
  void (*addCandidatesFromReads)(struct __pyx_obj_7variant_VariantCandidateGenerator *, __pyx_t_13htslibWrapper_cAlignedRead **, __pyx_t_13htslibWrapper_cAlignedRead **);
  PyObject *(*getCandidates)(struct __pyx_obj_7variant_VariantCandidateGenerator *, int);
};
static struct __pyx_vtabstruct_7variant_VariantCandidateGenerator *__pyx_vtabptr_7variant_VariantCandidateGenerator;
static void __pyx_f_7variant_25VariantCandidateGenerator_addVariantToList(struct __pyx_obj_7variant_VariantCandidateGenerator *, struct __pyx_obj_7variant_Variant *);
static void __pyx_f_7variant_25VariantCandidateGenerator_getSnpCandidatesFromReadSegment(struct __pyx_obj_7variant_VariantCandidateGenerator *, __pyx_t_13htslibWrapper_cAlignedRead *, char *, char *, int, int, int, int, int);
static void __pyx_f_7variant_25VariantCandidateGenerator_getVariantCandidatesFromSingleRead(struct __pyx_obj_7variant_VariantCandidateGenerator *, __pyx_t_13htslibWrapper_cAlignedRead *);
static void __pyx_f_7variant_25VariantCandidateGenerator_addCandidatesFromReads(struct __pyx_obj_7variant_VariantCandidateGenerator *, __pyx_t_13htslibWrapper_cAlignedRead **, __pyx_t_13htslibWrapper_cAlignedRead **);
static PyObject *__pyx_f_7variant_25VariantCandidateGenerator_getCandidates(struct __pyx_obj_7variant_VariantCandidateGenerator *, int);
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static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object);

static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename); /*proto*/

static int __Pyx_InitStrings(__Pyx_StringTabEntry *t); /*proto*/


/* Module declarations from 'cython' */

/* Module declarations from 'fastafile' */
static PyTypeObject *__pyx_ptype_9fastafile_FastaIndex = 0;
static PyTypeObject *__pyx_ptype_9fastafile_FastaFile = 0;

/* Module declarations from 'cpython.version' */

/* Module declarations from 'cpython.ref' */

/* Module declarations from 'cpython.exc' */

/* Module declarations from 'cpython.module' */

/* Module declarations from 'cpython.mem' */

/* Module declarations from 'cpython.tuple' */

/* Module declarations from 'cpython.list' */

/* Module declarations from 'libc.string' */

/* Module declarations from 'libc.stdio' */

/* Module declarations from 'cpython.object' */

/* Module declarations from 'cpython.sequence' */

/* Module declarations from 'cpython.mapping' */

/* Module declarations from 'cpython.iterator' */

/* Module declarations from '__builtin__' */

/* Module declarations from 'cpython.type' */
static PyTypeObject *__pyx_ptype_7cpython_4type_type = 0;

/* Module declarations from 'cpython.number' */

/* Module declarations from 'cpython.int' */

/* Module declarations from '__builtin__' */

/* Module declarations from 'cpython.bool' */
static PyTypeObject *__pyx_ptype_7cpython_4bool_bool = 0;

/* Module declarations from 'cpython.long' */

/* Module declarations from 'cpython.float' */

/* Module declarations from '__builtin__' */

/* Module declarations from 'cpython.complex' */
static PyTypeObject *__pyx_ptype_7cpython_7complex_complex = 0;

/* Module declarations from 'cpython.string' */

/* Module declarations from 'cpython.unicode' */

/* Module declarations from 'cpython.dict' */

/* Module declarations from 'cpython.instance' */

/* Module declarations from 'cpython.function' */

/* Module declarations from 'cpython.method' */

/* Module declarations from 'cpython.weakref' */

/* Module declarations from 'cpython.getargs' */

/* Module declarations from 'cpython.pythread' */

/* Module declarations from 'cpython.pystate' */

/* Module declarations from 'cpython.cobject' */

/* Module declarations from 'cpython.oldbuffer' */

/* Module declarations from 'cpython.set' */

/* Module declarations from 'cpython.buffer' */

/* Module declarations from 'cpython.bytes' */

/* Module declarations from 'cpython.pycapsule' */

/* Module declarations from 'cpython' */

/* Module declarations from 'htslibWrapper' */
static PyTypeObject *__pyx_ptype_13htslibWrapper_Samfile = 0;
static PyTypeObject *__pyx_ptype_13htslibWrapper_ReadIterator = 0;
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsReverse(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsPaired(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsProperPair(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsDuplicate(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsUnmapped(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_MateIsUnmapped(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsQCFail(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsReadOne(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsSecondaryAlignment(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsCompressed(__pyx_t_13htslibWrapper_cAlignedRead *); /*proto*/
static void (*__pyx_f_13htslibWrapper_compressRead)(__pyx_t_13htslibWrapper_cAlignedRead *, char *, int, int, int, int); /*proto*/
static void (*__pyx_f_13htslibWrapper_uncompressRead)(__pyx_t_13htslibWrapper_cAlignedRead *, char *, int, int, int); /*proto*/

/* Module declarations from 'cerrormodel' */
static PyObject *(*__pyx_f_11cerrormodel_calculate_size_and_displacement)(PyObject *, char); /*proto*/

/* Module declarations from 'variant' */
static PyTypeObject *__pyx_ptype_7variant_Variant = 0;
static PyTypeObject *__pyx_ptype_7variant_VariantCandidateGenerator = 0;
__PYX_EXTERN_C DL_EXPORT(int) PLATYPUS_VAR;
__PYX_EXTERN_C DL_EXPORT(int) FILE_VAR;
__PYX_EXTERN_C DL_EXPORT(int) ASSEMBLER_VAR;
static double __pyx_v_7variant_mLTOT;
static int __pyx_v_7variant_SNP;
static int __pyx_v_7variant_MNP;
static int __pyx_v_7variant_INS;
static int __pyx_v_7variant_DEL;
static int __pyx_v_7variant_REP;
static PyObject *__pyx_v_7variant_varTypes = 0;
static PyObject *__pyx_v_7variant_indel_prior_model = 0;
static double __pyx_v_7variant_complex_deletion_prior;
static double __pyx_v_7variant_complex_insertion_prior;
#define __Pyx_MODULE_NAME "variant"
int __pyx_module_is_main_variant = 0;

/* Implementation of 'variant' */
static PyObject *__pyx_builtin_IndexError;
static PyObject *__pyx_builtin_range;
static PyObject *__pyx_builtin_zip;
static PyObject *__pyx_builtin_sorted;
static int __pyx_pf_7variant_7Variant___init__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_refName, int __pyx_v_refPos, char *__pyx_v_removed, char *__pyx_v_added, int __pyx_v_nSupportingReads, int __pyx_v_varSource); /* proto */
static Py_hash_t __pyx_pf_7variant_7Variant_2__hash__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_4__richcmp__(struct __pyx_obj_7variant_Variant *__pyx_v_self, struct __pyx_obj_7variant_Variant *__pyx_v_other, int __pyx_v_opCode); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_6__str__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_8__repr__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_10shortRepr(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_7refName___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_7refName_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_7variant_7Variant_7refName_4__del__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_5added___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_5added_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_7variant_7Variant_5added_4__del__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_7removed___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_7removed_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_7variant_7Variant_7removed_4__del__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_8bamAdded___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_8bamAdded_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_7variant_7Variant_8bamAdded_4__del__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_10bamRemoved___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_10bamRemoved_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_7variant_7Variant_10bamRemoved_4__del__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_6refPos___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_6refPos_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_9bamMinPos___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_9bamMinPos_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_9bamMaxPos___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_9bamMaxPos_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_9minRefPos___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_9minRefPos_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_9maxRefPos___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_9maxRefPos_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_16nSupportingReads___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_16nSupportingReads_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_9varSource___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_9varSource_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_9hashValue___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_9hashValue_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_6nAdded___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_6nAdded_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_8nRemoved___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_8nRemoved_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_7variant_7Variant_7varType___get__(struct __pyx_obj_7variant_Variant *__pyx_v_self); /* proto */
static int __pyx_pf_7variant_7Variant_7varType_2__set__(struct __pyx_obj_7variant_Variant *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_7variant_25VariantCandidateGenerator___init__(struct __pyx_obj_7variant_VariantCandidateGenerator *__pyx_v_self, PyObject *__pyx_v_region, struct __pyx_obj_9fastafile_FastaFile *__pyx_v_referenceFile, int __pyx_v_minMapQual, int __pyx_v_minFlank, int __pyx_v_minBaseQual, int __pyx_v_maxCoverage, int __pyx_v_maxReadLength, PyObject *__pyx_v_options, int __pyx_v_verbosity, int __pyx_v_genSNPs, int __pyx_v_genIndels); /* proto */
static PyObject *__pyx_tp_new_7variant_Variant(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_7variant_VariantCandidateGenerator(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static char __pyx_k_1[] = "";
static char __pyx_k_2[] = "%s(%s:%s-%s";
static char __pyx_k_3[] = " -";
static char __pyx_k_4[] = " +";
static char __pyx_k_5[] = " nReads = %s, Source= %s";
static char __pyx_k_6[] = ")";
static char __pyx_k_7[] = "Adding new variant %s to candidate list";
static char __pyx_k_8[] = "Adding variant %s to existing variant in candidate list";
static char __pyx_k_9[] = "Something is very wrong. Base qual is %s";
static char __pyx_k_10[] = "Splitting long mis-match into two variants at %s.";
static char __pyx_k_13[] = "\nUtility module, containing classes to handle reading and writing\nfiles of variants.\n";
static char __pyx_k_15[] = "LIGC@:62/-*'&%$";
static char __pyx_k_16[] = "LIGDB@><9630.,+**)(''&&%%%$$$";
static char __pyx_k_17[] = "LIGA@B@><;8763220/.-,+++)*))(((''''&&&&&&%%%%%%%%$$$$$$$";
static char __pyx_k_18[] = "LIGA@\077\077?=<886533210/.--,+**))))((('''''&&&&&&&&%%%%%%%%%%%$$$$$$$$";
static char __pyx_k_19[] = "LIGA@\077\077>=>=;966543210///-,,++*";
static char __pyx_k_20[] = "LIGA@\077\077>>=<=;:764532210/----,++";
static char __pyx_k_21[] = "LIGA@\077\077>>==<;;987543210/....-,,,++++";
static char __pyx_k_22[] = "LIGA@\077\077>>==<<;9876432200/..--,,,+++";
static char __pyx_k_23[] = "LIGA@\077\077>>==<<;;9966432100//../..----,,,,,++++++";
static char __pyx_k_24[] = "LIGA@\077\077>>==<<;;:986432110//..----,,,,++++";
static char __pyx_k_25[] = "LIGA@\077\077>>==<<<;;:87642210////..--,,,,,+++";
static char __pyx_k_26[] = "LIGA@\077\077>>==<<<;;;:986532110000/...-----,,,,,+++++";
static char __pyx_k_27[] = "LIGA@\077\077>>==<<<;;;::987543111000/////.......--------,,,,,,,,,,,,,+++++++++";
static char __pyx_k_28[] = "LIGA@\077\077>>==<<<;;;::987642210/0/.....-------,,,,,,,,+++++++";
static char __pyx_k_29[] = "LIGA@\077\077>>==<<<;;;;::988754322110000////////.......------------,,,,,,,,,,,,,,,,,++++++++++";
static char __pyx_k_30[] = "LIGA@\077\077>>==<<<;;;;:::98765321110////........-------,,,,,,,,,,,,,,+++++++++";
static char __pyx_k_31[] = "LIGA@\077\077>>==<<<;;;;::::988764433211110000000///////.............-----------------,,,,,,,,,,,,,,,,,,,";
static char __pyx_k_32[] = "LIGA@\077\077>>==<<<;;;:::::998875433221111000000///////.............-----------------,,,,,,,,,,,,,,,,,,,";
static char __pyx_k_33[] = "LIGA@\077\077>>==<<<;;;;::::999887654433222221111111100000000//////////////..................------------";
static char __pyx_k_34[] = "LIGA@\077\077>>==<<<;;;;::::9999876543322111000000///////............-----------------,,,,,,,,,,,,,,,,,,,";
static char __pyx_k_35[] = "LIGA@\077\077>>==<<<;;;;::::9999988765544433322222221111111100000000000000//////////////////.............";
static char __pyx_k_36[] = "LIGA@\077\077>>==<<<;;;;::::9999987765432221000000////////...........-----------------,,,,,,,,,,,,,,,,,,,";
static char __pyx_k_37[] = "LIGA@\077\077>>==<<<;;;;::::9999998776543322111100000000////////................-------------------,,,,,,";
static char __pyx_k_38[] = "LIGA@\077\077>>==<<<;;;;::::9999998887654433322111111100000000/////////////...................-----------";
static char __pyx_k__N[] = "N";
static char __pyx_k__DEL[] = "DEL";
static char __pyx_k__INS[] = "INS";
static char __pyx_k__Log[] = "Log";
static char __pyx_k__MNP[] = "MNP";
static char __pyx_k__REP[] = "REP";
static char __pyx_k__SNP[] = "SNP";
static char __pyx_k__get[] = "get";
static char __pyx_k__pow[] = "pow";
static char __pyx_k__zip[] = "zip";
static char __pyx_k__math[] = "math";
static char __pyx_k__added[] = "added";
static char __pyx_k__count[] = "count";
static char __pyx_k__debug[] = "debug";
static char __pyx_k__range[] = "range";
static char __pyx_k__logger[] = "logger";
static char __pyx_k__refPos[] = "refPos";
static char __pyx_k__region[] = "region";
static char __pyx_k__sorted[] = "sorted";
static char __pyx_k__values[] = "values";
static char __pyx_k__genSNPs[] = "genSNPs";
static char __pyx_k__logging[] = "logging";
static char __pyx_k__options[] = "options";
static char __pyx_k__refName[] = "refName";
static char __pyx_k__removed[] = "removed";
static char __pyx_k__FILE_VAR[] = "FILE_VAR";
static char __pyx_k____main__[] = "__main__";
static char __pyx_k____test__[] = "__test__";
static char __pyx_k__datetime[] = "datetime";
static char __pyx_k__minFlank[] = "minFlank";
static char __pyx_k__SeqLength[] = "SeqLength";
static char __pyx_k__fastafile[] = "fastafile";
static char __pyx_k__genIndels[] = "genIndels";
static char __pyx_k__getLogger[] = "getLogger";
static char __pyx_k__varSource[] = "varSource";
static char __pyx_k__verbosity[] = "verbosity";
static char __pyx_k__IndexError[] = "IndexError";
static char __pyx_k____import__[] = "__import__";
static char __pyx_k__minMapQual[] = "minMapQual";
static char __pyx_k__maxCoverage[] = "maxCoverage";
static char __pyx_k__minBaseQual[] = "minBaseQual";
static char __pyx_k__qualBinSize[] = "qualBinSize";
static char __pyx_k__PLATYPUS_VAR[] = "PLATYPUS_VAR";
static char __pyx_k____pyx_capi__[] = "__pyx_capi__";
static char __pyx_k__ASSEMBLER_VAR[] = "ASSEMBLER_VAR";
static char __pyx_k__htslibWrapper[] = "htslibWrapper";
static char __pyx_k__maxReadLength[] = "maxReadLength";
static char __pyx_k__referenceFile[] = "referenceFile";
static char __pyx_k____pyx_vtable__[] = "__pyx_vtable__";
static char __pyx_k__nSupportingReads[] = "nSupportingReads";
static PyObject *__pyx_kp_s_1;
static PyObject *__pyx_kp_s_10;
static PyObject *__pyx_kp_s_15;
static PyObject *__pyx_kp_s_16;
static PyObject *__pyx_kp_s_17;
static PyObject *__pyx_kp_s_18;
static PyObject *__pyx_kp_s_19;
static PyObject *__pyx_kp_s_2;
static PyObject *__pyx_kp_s_20;
static PyObject *__pyx_kp_s_21;
static PyObject *__pyx_kp_s_22;
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static PyObject *__pyx_kp_s_25;
static PyObject *__pyx_kp_s_26;
static PyObject *__pyx_kp_s_27;
static PyObject *__pyx_kp_s_28;
static PyObject *__pyx_kp_s_29;
static PyObject *__pyx_kp_s_3;
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static PyObject *__pyx_kp_s_31;
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static PyObject *__pyx_kp_s_33;
static PyObject *__pyx_kp_s_34;
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static PyObject *__pyx_kp_s_36;
static PyObject *__pyx_kp_s_37;
static PyObject *__pyx_kp_s_38;
static PyObject *__pyx_kp_s_4;
static PyObject *__pyx_kp_s_5;
static PyObject *__pyx_kp_s_6;
static PyObject *__pyx_kp_s_7;
static PyObject *__pyx_kp_s_8;
static PyObject *__pyx_kp_s_9;
static PyObject *__pyx_n_s__ASSEMBLER_VAR;
static PyObject *__pyx_n_s__DEL;
static PyObject *__pyx_n_s__FILE_VAR;
static PyObject *__pyx_n_s__INS;
static PyObject *__pyx_n_s__IndexError;
static PyObject *__pyx_n_s__Log;
static PyObject *__pyx_n_s__MNP;
static PyObject *__pyx_n_s__N;
static PyObject *__pyx_n_s__PLATYPUS_VAR;
static PyObject *__pyx_n_s__REP;
static PyObject *__pyx_n_s__SNP;
static PyObject *__pyx_n_s__SeqLength;
static PyObject *__pyx_n_s____import__;
static PyObject *__pyx_n_s____main__;
static PyObject *__pyx_n_s____pyx_capi__;
static PyObject *__pyx_n_s____pyx_vtable__;
static PyObject *__pyx_n_s____test__;
static PyObject *__pyx_n_s__added;
static PyObject *__pyx_n_s__count;
static PyObject *__pyx_n_s__datetime;
static PyObject *__pyx_n_s__debug;
static PyObject *__pyx_n_s__fastafile;
static PyObject *__pyx_n_s__genIndels;
static PyObject *__pyx_n_s__genSNPs;
static PyObject *__pyx_n_s__get;
static PyObject *__pyx_n_s__getLogger;
static PyObject *__pyx_n_s__htslibWrapper;
static PyObject *__pyx_n_s__logger;
static PyObject *__pyx_n_s__logging;
static PyObject *__pyx_n_s__math;
static PyObject *__pyx_n_s__maxCoverage;
static PyObject *__pyx_n_s__maxReadLength;
static PyObject *__pyx_n_s__minBaseQual;
static PyObject *__pyx_n_s__minFlank;
static PyObject *__pyx_n_s__minMapQual;
static PyObject *__pyx_n_s__nSupportingReads;
static PyObject *__pyx_n_s__options;
static PyObject *__pyx_n_s__pow;
static PyObject *__pyx_n_s__qualBinSize;
static PyObject *__pyx_n_s__range;
static PyObject *__pyx_n_s__refName;
static PyObject *__pyx_n_s__refPos;
static PyObject *__pyx_n_s__referenceFile;
static PyObject *__pyx_n_s__region;
static PyObject *__pyx_n_s__removed;
static PyObject *__pyx_n_s__sorted;
static PyObject *__pyx_n_s__values;
static PyObject *__pyx_n_s__varSource;
static PyObject *__pyx_n_s__verbosity;
static PyObject *__pyx_n_s__zip;
static PyObject *__pyx_int_0;
static PyObject *__pyx_int_1;
static PyObject *__pyx_int_2;
static PyObject *__pyx_int_3;
static PyObject *__pyx_int_4;
static PyObject *__pyx_int_5;
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/* "variant.pyx":463
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 *         """
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/* "variant.pyx":518
 *                 logger.debug("Adding variant %s to existing variant in candidate list" %(var))
 * 
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 *         """
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 */

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 *         cdef int misMatchEndRead   = -1
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 *             # Don't look at the first 'minFlank' bases for candidate generation
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 *             # Don't look at the last 'minFlank' bases for candidate generation
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 */
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 * 
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 * 
 * cdef inline int Read_IsPaired(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FPAIRED) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsProperPair(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 1) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":256
 *     return ( (theRead.bitFlag & BAM_FPAIRED) != 0)
 * 
 * cdef inline int Read_IsProperPair(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FPROPER_PAIR) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsProperPair(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":257
 * 
 * cdef inline int Read_IsProperPair(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FPROPER_PAIR) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsDuplicate(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 2) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":259
 *     return ( (theRead.bitFlag & BAM_FPROPER_PAIR) != 0)
 * 
 * cdef inline int Read_IsDuplicate(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FDUP) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsDuplicate(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":260
 * 
 * cdef inline int Read_IsDuplicate(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FDUP) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsUnmapped(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 1024) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":262
 *     return ( (theRead.bitFlag & BAM_FDUP) != 0)
 * 
 * cdef inline int Read_IsUnmapped(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FUNMAP) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsUnmapped(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":263
 * 
 * cdef inline int Read_IsUnmapped(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FUNMAP) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_MateIsUnmapped(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 4) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":265
 *     return ( (theRead.bitFlag & BAM_FUNMAP) != 0)
 * 
 * cdef inline int Read_MateIsUnmapped(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FMUNMAP) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_MateIsUnmapped(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":266
 * 
 * cdef inline int Read_MateIsUnmapped(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FMUNMAP) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_MateIsReverse(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 8) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":268
 *     return ( (theRead.bitFlag & BAM_FMUNMAP) != 0)
 * 
 * cdef inline int Read_MateIsReverse(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FMREVERSE) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_MateIsReverse(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":269
 * 
 * cdef inline int Read_MateIsReverse(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FMREVERSE) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsQCFail(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 32) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":271
 *     return ( (theRead.bitFlag & BAM_FMREVERSE) != 0)
 * 
 * cdef inline int Read_IsQCFail(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FQCFAIL) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsQCFail(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":272
 * 
 * cdef inline int Read_IsQCFail(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FQCFAIL) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsReadOne(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 512) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":274
 *     return ( (theRead.bitFlag & BAM_FQCFAIL) != 0)
 * 
 * cdef inline int Read_IsReadOne(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FREAD1) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsReadOne(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":275
 * 
 * cdef inline int Read_IsReadOne(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FREAD1) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsSecondaryAlignment(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 64) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":277
 *     return ( (theRead.bitFlag & BAM_FREAD1) != 0)
 * 
 * cdef inline int Read_IsSecondaryAlignment(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FSECONDARY) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsSecondaryAlignment(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":278
 * 
 * cdef inline int Read_IsSecondaryAlignment(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FSECONDARY) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_IsCompressed(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 256) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":280
 *     return ( (theRead.bitFlag & BAM_FSECONDARY) != 0)
 * 
 * cdef inline int Read_IsCompressed(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     return ( (theRead.bitFlag & BAM_FCOMPRESSED) != 0)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_IsCompressed(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":281
 * 
 * cdef inline int Read_IsCompressed(cAlignedRead* theRead) nogil:
 *     return ( (theRead.bitFlag & BAM_FCOMPRESSED) != 0)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_SetIsNotReverse(cAlignedRead* theRead) nogil:
 */
  __pyx_r = ((__pyx_v_theRead->bitFlag & 2048) != 0);
  goto __pyx_L0;

  __pyx_r = 0;
  __pyx_L0:;
  return __pyx_r;
}

/* "htslibWrapper.pxd":283
 *     return ( (theRead.bitFlag & BAM_FCOMPRESSED) != 0)
 * 
 * cdef inline int Read_SetIsNotReverse(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     theRead.bitFlag &= (~BAM_FREVERSE)
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_SetIsNotReverse(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":284
 * 
 * cdef inline int Read_SetIsNotReverse(cAlignedRead* theRead) nogil:
 *     theRead.bitFlag &= (~BAM_FREVERSE)             # <<<<<<<<<<<<<<
 * 
 * cdef inline int Read_SetIsReverse(cAlignedRead* theRead) nogil:
 */
  __pyx_v_theRead->bitFlag = (__pyx_v_theRead->bitFlag & (~16));

  __pyx_r = 0;
  return __pyx_r;
}

/* "htslibWrapper.pxd":286
 *     theRead.bitFlag &= (~BAM_FREVERSE)
 * 
 * cdef inline int Read_SetIsReverse(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     theRead.bitFlag |= BAM_FREVERSE
 * 
 */

static CYTHON_INLINE int __pyx_f_13htslibWrapper_Read_SetIsReverse(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {
  int __pyx_r;

  /* "htslibWrapper.pxd":287
 * 
 * cdef inline int Read_SetIsReverse(cAlignedRead* theRead) nogil:
 *     theRead.bitFlag |= BAM_FREVERSE             # <<<<<<<<<<<<<<
 * 
 * cdef inline void Read_SetQCFail(cAlignedRead* theRead) nogil:
 */
  __pyx_v_theRead->bitFlag = (__pyx_v_theRead->bitFlag | 16);

  __pyx_r = 0;
  return __pyx_r;
}

/* "htslibWrapper.pxd":289
 *     theRead.bitFlag |= BAM_FREVERSE
 * 
 * cdef inline void Read_SetQCFail(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     theRead.bitFlag |= BAM_FQCFAIL
 * 
 */

static CYTHON_INLINE void __pyx_f_13htslibWrapper_Read_SetQCFail(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {

  /* "htslibWrapper.pxd":290
 * 
 * cdef inline void Read_SetQCFail(cAlignedRead* theRead) nogil:
 *     theRead.bitFlag |= BAM_FQCFAIL             # <<<<<<<<<<<<<<
 * 
 * cdef inline void Read_SetCompressed(cAlignedRead* theRead) nogil:
 */
  __pyx_v_theRead->bitFlag = (__pyx_v_theRead->bitFlag | 512);

}

/* "htslibWrapper.pxd":292
 *     theRead.bitFlag |= BAM_FQCFAIL
 * 
 * cdef inline void Read_SetCompressed(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     theRead.bitFlag |= BAM_FCOMPRESSED
 * 
 */

static CYTHON_INLINE void __pyx_f_13htslibWrapper_Read_SetCompressed(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {

  /* "htslibWrapper.pxd":293
 * 
 * cdef inline void Read_SetCompressed(cAlignedRead* theRead) nogil:
 *     theRead.bitFlag |= BAM_FCOMPRESSED             # <<<<<<<<<<<<<<
 * 
 * cdef inline void Read_SetUnCompressed(cAlignedRead* theRead) nogil:
 */
  __pyx_v_theRead->bitFlag = (__pyx_v_theRead->bitFlag | 2048);

}

/* "htslibWrapper.pxd":295
 *     theRead.bitFlag |= BAM_FCOMPRESSED
 * 
 * cdef inline void Read_SetUnCompressed(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     theRead.bitFlag &= (~BAM_FCOMPRESSED)
 * 
 */

static CYTHON_INLINE void __pyx_f_13htslibWrapper_Read_SetUnCompressed(__pyx_t_13htslibWrapper_cAlignedRead *__pyx_v_theRead) {

  /* "htslibWrapper.pxd":296
 * 
 * cdef inline void Read_SetUnCompressed(cAlignedRead* theRead) nogil:
 *     theRead.bitFlag &= (~BAM_FCOMPRESSED)             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __pyx_v_theRead->bitFlag = (__pyx_v_theRead->bitFlag & (~2048));

}
static struct __pyx_vtabstruct_7variant_Variant __pyx_vtable_7variant_Variant;

static PyObject *__pyx_tp_new_7variant_Variant(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_7variant_Variant *p;
  PyObject *o;
  o = (*t->tp_alloc)(t, 0);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_7variant_Variant *)o);
  p->__pyx_vtab = __pyx_vtabptr_7variant_Variant;
  p->refName = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->added = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->removed = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->bamAdded = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->bamRemoved = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_7variant_Variant(PyObject *o) {
  struct __pyx_obj_7variant_Variant *p = (struct __pyx_obj_7variant_Variant *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->refName);
  Py_CLEAR(p->added);
  Py_CLEAR(p->removed);
  Py_CLEAR(p->bamAdded);
  Py_CLEAR(p->bamRemoved);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_7variant_Variant(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_7variant_Variant *p = (struct __pyx_obj_7variant_Variant *)o;
  if (p->refName) {
    e = (*v)(p->refName, a); if (e) return e;
  }
  if (p->added) {
    e = (*v)(p->added, a); if (e) return e;
  }
  if (p->removed) {
    e = (*v)(p->removed, a); if (e) return e;
  }
  if (p->bamAdded) {
    e = (*v)(p->bamAdded, a); if (e) return e;
  }
  if (p->bamRemoved) {
    e = (*v)(p->bamRemoved, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_7variant_Variant(PyObject *o) {
  struct __pyx_obj_7variant_Variant *p = (struct __pyx_obj_7variant_Variant *)o;
  PyObject* tmp;
  tmp = ((PyObject*)p->refName);
  p->refName = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->added);
  p->added = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->removed);
  p->removed = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->bamAdded);
  p->bamAdded = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->bamRemoved);
  p->bamRemoved = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_7variant_7Variant_refName(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_7refName_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_refName(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_7refName_3__set__(o, v);
  }
  else {
    return __pyx_pw_7variant_7Variant_7refName_5__del__(o);
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_added(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_5added_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_added(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_5added_3__set__(o, v);
  }
  else {
    return __pyx_pw_7variant_7Variant_5added_5__del__(o);
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_removed(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_7removed_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_removed(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_7removed_3__set__(o, v);
  }
  else {
    return __pyx_pw_7variant_7Variant_7removed_5__del__(o);
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_bamAdded(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_8bamAdded_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_bamAdded(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_8bamAdded_3__set__(o, v);
  }
  else {
    return __pyx_pw_7variant_7Variant_8bamAdded_5__del__(o);
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_bamRemoved(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_10bamRemoved_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_bamRemoved(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_10bamRemoved_3__set__(o, v);
  }
  else {
    return __pyx_pw_7variant_7Variant_10bamRemoved_5__del__(o);
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_refPos(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_6refPos_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_refPos(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_6refPos_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_bamMinPos(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_9bamMinPos_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_bamMinPos(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_9bamMinPos_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_bamMaxPos(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_9bamMaxPos_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_bamMaxPos(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_9bamMaxPos_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_minRefPos(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_9minRefPos_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_minRefPos(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_9minRefPos_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_maxRefPos(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_9maxRefPos_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_maxRefPos(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_9maxRefPos_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_nSupportingReads(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_16nSupportingReads_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_nSupportingReads(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_16nSupportingReads_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_varSource(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_9varSource_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_varSource(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_7variant_7Variant_9varSource_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_hashValue(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_9hashValue_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_hashValue(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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    return __pyx_pw_7variant_7Variant_9hashValue_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_nAdded(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_7variant_7Variant_6nAdded_1__get__(o);
}

static int __pyx_setprop_7variant_7Variant_nAdded(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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  }
}

static PyObject *__pyx_getprop_7variant_7Variant_nRemoved(PyObject *o, CYTHON_UNUSED void *x) {
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}

static int __pyx_setprop_7variant_7Variant_nRemoved(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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    return __pyx_pw_7variant_7Variant_8nRemoved_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_7variant_7Variant_varType(PyObject *o, CYTHON_UNUSED void *x) {
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}

static int __pyx_setprop_7variant_7Variant_varType(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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    return __pyx_pw_7variant_7Variant_7varType_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_7variant_Variant[] = {
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};

static struct PyGetSetDef __pyx_getsets_7variant_Variant[] = {
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  {(char *)"added", __pyx_getprop_7variant_7Variant_added, __pyx_setprop_7variant_7Variant_added, 0, 0},
  {(char *)"removed", __pyx_getprop_7variant_7Variant_removed, __pyx_setprop_7variant_7Variant_removed, 0, 0},
  {(char *)"bamAdded", __pyx_getprop_7variant_7Variant_bamAdded, __pyx_setprop_7variant_7Variant_bamAdded, 0, 0},
  {(char *)"bamRemoved", __pyx_getprop_7variant_7Variant_bamRemoved, __pyx_setprop_7variant_7Variant_bamRemoved, 0, 0},
  {(char *)"refPos", __pyx_getprop_7variant_7Variant_refPos, __pyx_setprop_7variant_7Variant_refPos, 0, 0},
  {(char *)"bamMinPos", __pyx_getprop_7variant_7Variant_bamMinPos, __pyx_setprop_7variant_7Variant_bamMinPos, 0, 0},
  {(char *)"bamMaxPos", __pyx_getprop_7variant_7Variant_bamMaxPos, __pyx_setprop_7variant_7Variant_bamMaxPos, 0, 0},
  {(char *)"minRefPos", __pyx_getprop_7variant_7Variant_minRefPos, __pyx_setprop_7variant_7Variant_minRefPos, 0, 0},
  {(char *)"maxRefPos", __pyx_getprop_7variant_7Variant_maxRefPos, __pyx_setprop_7variant_7Variant_maxRefPos, 0, 0},
  {(char *)"nSupportingReads", __pyx_getprop_7variant_7Variant_nSupportingReads, __pyx_setprop_7variant_7Variant_nSupportingReads, 0, 0},
  {(char *)"varSource", __pyx_getprop_7variant_7Variant_varSource, __pyx_setprop_7variant_7Variant_varSource, 0, 0},
  {(char *)"hashValue", __pyx_getprop_7variant_7Variant_hashValue, __pyx_setprop_7variant_7Variant_hashValue, 0, 0},
  {(char *)"nAdded", __pyx_getprop_7variant_7Variant_nAdded, __pyx_setprop_7variant_7Variant_nAdded, 0, 0},
  {(char *)"nRemoved", __pyx_getprop_7variant_7Variant_nRemoved, __pyx_setprop_7variant_7Variant_nRemoved, 0, 0},
  {(char *)"varType", __pyx_getprop_7variant_7Variant_varType, __pyx_setprop_7variant_7Variant_varType, 0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_7variant_Variant = {
  PyVarObject_HEAD_INIT(0, 0)
  __Pyx_NAMESTR("variant.Variant"), /*tp_name*/
  sizeof(struct __pyx_obj_7variant_Variant), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_7variant_Variant, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #else
  0, /*reserved*/
  #endif
  __pyx_pw_7variant_7Variant_9__repr__, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  __pyx_pw_7variant_7Variant_3__hash__, /*tp_hash*/
  0, /*tp_call*/
  __pyx_pw_7variant_7Variant_7__str__, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
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  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  __Pyx_DOCSTR("\n    Class to encapsulate information for all common variant types. The basic\n    idea is to tread all variants as replacements, i.e. a certain sequence of\n    bases is removed from the reference, and a certain sequence is added. A SNP is\n    a replacement of 1 base with 1 different base, a deletion is a replacement of one\n    sequence with a smaller sequence (or none at all), and an insertion is a replacement\n    of one sequence with a longer sequence.\n    "), /*tp_doc*/
  __pyx_tp_traverse_7variant_Variant, /*tp_traverse*/
  __pyx_tp_clear_7variant_Variant, /*tp_clear*/
  __pyx_pw_7variant_7Variant_5__richcmp__, /*tp_richcompare*/
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  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_7variant_Variant, /*tp_methods*/
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  0, /*tp_base*/
  0, /*tp_dict*/
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  0, /*tp_descr_set*/
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  0, /*tp_alloc*/
  __pyx_tp_new_7variant_Variant, /*tp_new*/
  0, /*tp_free*/
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  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  #if PY_VERSION_HEX >= 0x02060000
  0, /*tp_version_tag*/
  #endif
};
static struct __pyx_vtabstruct_7variant_VariantCandidateGenerator __pyx_vtable_7variant_VariantCandidateGenerator;

static PyObject *__pyx_tp_new_7variant_VariantCandidateGenerator(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_7variant_VariantCandidateGenerator *p;
  PyObject *o;
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  p = ((struct __pyx_obj_7variant_VariantCandidateGenerator *)o);
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  p->variantHeap = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->pyRefSeq = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->rname = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->refFile = ((struct __pyx_obj_9fastafile_FastaFile *)Py_None); Py_INCREF(Py_None);
  p->options = Py_None; Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_7variant_VariantCandidateGenerator(PyObject *o) {
  struct __pyx_obj_7variant_VariantCandidateGenerator *p = (struct __pyx_obj_7variant_VariantCandidateGenerator *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->variantHeap);
  Py_CLEAR(p->pyRefSeq);
  Py_CLEAR(p->rname);
  Py_CLEAR(p->refFile);
  Py_CLEAR(p->options);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_7variant_VariantCandidateGenerator(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_7variant_VariantCandidateGenerator *p = (struct __pyx_obj_7variant_VariantCandidateGenerator *)o;
  if (p->variantHeap) {
    e = (*v)(p->variantHeap, a); if (e) return e;
  }
  if (p->pyRefSeq) {
    e = (*v)(p->pyRefSeq, a); if (e) return e;
  }
  if (p->rname) {
    e = (*v)(p->rname, a); if (e) return e;
  }
  if (p->refFile) {
    e = (*v)(((PyObject*)p->refFile), a); if (e) return e;
  }
  if (p->options) {
    e = (*v)(p->options, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_7variant_VariantCandidateGenerator(PyObject *o) {
  struct __pyx_obj_7variant_VariantCandidateGenerator *p = (struct __pyx_obj_7variant_VariantCandidateGenerator *)o;
  PyObject* tmp;
  tmp = ((PyObject*)p->variantHeap);
  p->variantHeap = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->pyRefSeq);
  p->pyRefSeq = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->rname);
  p->rname = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->refFile);
  p->refFile = ((struct __pyx_obj_9fastafile_FastaFile *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->options);
  p->options = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyMethodDef __pyx_methods_7variant_VariantCandidateGenerator[] = {
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};

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  __Pyx_DOCSTR("\n    A class to generate variant candidates from a bunch of reads.\n    "), /*tp_doc*/
  __pyx_tp_traverse_7variant_VariantCandidateGenerator, /*tp_traverse*/
  __pyx_tp_clear_7variant_VariantCandidateGenerator, /*tp_clear*/
  0, /*tp_richcompare*/
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  __pyx_pw_7variant_25VariantCandidateGenerator_1__init__, /*tp_init*/
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  __pyx_tp_new_7variant_VariantCandidateGenerator, /*tp_new*/
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#if PY_MAJOR_VERSION < 3
PyMODINIT_FUNC initvariant(void); /*proto*/
PyMODINIT_FUNC initvariant(void)
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PyMODINIT_FUNC PyInit_variant(void)
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  /* "variant.pyx":94
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 * # Currently hard-coded insertion/deletion priors
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 * cdef double complex_insertion_prior = 5e-6
 * 
 */
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  /* "variant.pyx":95
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 * cdef double complex_insertion_prior = 5e-6             # <<<<<<<<<<<<<<
 * 
 * ###################################################################################################
 */
  __pyx_v_7variant_complex_insertion_prior = 5e-6;

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 * Utility module, containing classes to handle reading and writing
 * files of variants.
 */
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  if (PyDict_SetItem(__pyx_d, __pyx_n_s____test__, ((PyObject *)__pyx_t_3)) < 0) {__pyx_filename = __pyx_f[0]; __pyx_lineno = 1; __pyx_clineno = __LINE__; goto __pyx_L1_error;}
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  /* "htslibWrapper.pxd":295
 *     theRead.bitFlag |= BAM_FCOMPRESSED
 * 
 * cdef inline void Read_SetUnCompressed(cAlignedRead* theRead) nogil:             # <<<<<<<<<<<<<<
 *     theRead.bitFlag &= (~BAM_FCOMPRESSED)
 * 
 */
  goto __pyx_L0;
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  __Pyx_XDECREF(__pyx_t_2);
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    Py_DECREF(__pyx_m); __pyx_m = 0;
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    PyErr_SetString(PyExc_ImportError, "init variant");
  }
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  #if PY_MAJOR_VERSION < 3
  return;
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  return __pyx_m;
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}

/* Runtime support code */
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static __Pyx_RefNannyAPIStruct *__Pyx_RefNannyImportAPI(const char *modname) {
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    p = PyObject_GetAttrString(m, (char *)"RefNannyAPI");
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end:
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static PyObject *__Pyx_GetBuiltinName(PyObject *name) {
    PyObject* result = __Pyx_PyObject_GetAttrStr(__pyx_b, name);
    if (unlikely(!result)) {
        PyErr_Format(PyExc_NameError,
#if PY_MAJOR_VERSION >= 3
            "name '%U' is not defined", name);
#else
            "name '%s' is not defined", PyString_AS_STRING(name));
#endif
    }
    return result;
}

static void __Pyx_RaiseArgtupleInvalid(
    const char* func_name,
    int exact,
    Py_ssize_t num_min,
    Py_ssize_t num_max,
    Py_ssize_t num_found)
{
    Py_ssize_t num_expected;
    const char *more_or_less;
    if (num_found < num_min) {
        num_expected = num_min;
        more_or_less = "at least";
    } else {
        num_expected = num_max;
        more_or_less = "at most";
    }
    if (exact) {
        more_or_less = "exactly";
    }
    PyErr_Format(PyExc_TypeError,
                 "%s() takes %s %" CYTHON_FORMAT_SSIZE_T "d positional argument%s (%" CYTHON_FORMAT_SSIZE_T "d given)",
                 func_name, more_or_less, num_expected,
                 (num_expected == 1) ? "" : "s", num_found);
}

static void __Pyx_RaiseDoubleKeywordsError(
    const char* func_name,
    PyObject* kw_name)
{
    PyErr_Format(PyExc_TypeError,
        #if PY_MAJOR_VERSION >= 3
        "%s() got multiple values for keyword argument '%U'", func_name, kw_name);
        #else
        "%s() got multiple values for keyword argument '%s'", func_name,
        PyString_AsString(kw_name));
        #endif
}

static int __Pyx_ParseOptionalKeywords(
    PyObject *kwds,
    PyObject **argnames[],
    PyObject *kwds2,
    PyObject *values[],
    Py_ssize_t num_pos_args,
    const char* function_name)
{
    PyObject *key = 0, *value = 0;
    Py_ssize_t pos = 0;
    PyObject*** name;
    PyObject*** first_kw_arg = argnames + num_pos_args;
    while (PyDict_Next(kwds, &pos, &key, &value)) {
        name = first_kw_arg;
        while (*name && (**name != key)) name++;
        if (*name) {
            values[name-argnames] = value;
            continue;
        }
        name = first_kw_arg;
        #if PY_MAJOR_VERSION < 3
        if (likely(PyString_CheckExact(key)) || likely(PyString_Check(key))) {
            while (*name) {
                if ((CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**name) == PyString_GET_SIZE(key))
                        && _PyString_Eq(**name, key)) {
                    values[name-argnames] = value;
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    if ((**argname == key) || (
                            (CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**argname) == PyString_GET_SIZE(key))
                             && _PyString_Eq(**argname, key))) {
                        goto arg_passed_twice;
                    }
                    argname++;
                }
            }
        } else
        #endif
        if (likely(PyUnicode_Check(key))) {
            while (*name) {
                int cmp = (**name == key) ? 0 :
                #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                    (PyUnicode_GET_SIZE(**name) != PyUnicode_GET_SIZE(key)) ? 1 :
                #endif
                    PyUnicode_Compare(**name, key);
                if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                if (cmp == 0) {
                    values[name-argnames] = value;
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    int cmp = (**argname == key) ? 0 :
                    #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                        (PyUnicode_GET_SIZE(**argname) != PyUnicode_GET_SIZE(key)) ? 1 :
                    #endif
                        PyUnicode_Compare(**argname, key);
                    if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                    if (cmp == 0) goto arg_passed_twice;
                    argname++;
                }
            }
        } else
            goto invalid_keyword_type;
        if (kwds2) {
            if (unlikely(PyDict_SetItem(kwds2, key, value))) goto bad;
        } else {
            goto invalid_keyword;
        }
    }
    return 0;
arg_passed_twice:
    __Pyx_RaiseDoubleKeywordsError(function_name, key);
    goto bad;
invalid_keyword_type:
    PyErr_Format(PyExc_TypeError,
        "%s() keywords must be strings", function_name);
    goto bad;
invalid_keyword:
    PyErr_Format(PyExc_TypeError,
    #if PY_MAJOR_VERSION < 3
        "%s() got an unexpected keyword argument '%s'",
        function_name, PyString_AsString(key));
    #else
        "%s() got an unexpected keyword argument '%U'",
        function_name, key);
    #endif
bad:
    return -1;
}

static int __Pyx_ArgTypeTest(PyObject *obj, PyTypeObject *type, int none_allowed,
    const char *name, int exact)
{
    if (!type) {
        PyErr_Format(PyExc_SystemError, "Missing type object");
        return 0;
    }
    if (none_allowed && obj == Py_None) return 1;
    else if (exact) {
        if (Py_TYPE(obj) == type) return 1;
    }
    else {
        if (PyObject_TypeCheck(obj, type)) return 1;
    }
    PyErr_Format(PyExc_TypeError,
        "Argument '%s' has incorrect type (expected %s, got %s)",
        name, type->tp_name, Py_TYPE(obj)->tp_name);
    return 0;
}

static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j) {
    PyObject *r;
    if (!j) return NULL;
    r = PyObject_GetItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck) {
#if CYTHON_COMPILING_IN_CPYTHON
    if (wraparound & unlikely(i < 0)) i += PyList_GET_SIZE(o);
    if ((!boundscheck) || likely((0 <= i) & (i < PyList_GET_SIZE(o)))) {
        PyObject *r = PyList_GET_ITEM(o, i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck) {
#if CYTHON_COMPILING_IN_CPYTHON
    if (wraparound & unlikely(i < 0)) i += PyTuple_GET_SIZE(o);
    if ((!boundscheck) || likely((0 <= i) & (i < PyTuple_GET_SIZE(o)))) {
        PyObject *r = PyTuple_GET_ITEM(o, i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i,
                                                     int is_list, int wraparound, int boundscheck) {
#if CYTHON_COMPILING_IN_CPYTHON
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyList_GET_SIZE(o);
        if ((!boundscheck) || (likely((n >= 0) & (n < PyList_GET_SIZE(o))))) {
            PyObject *r = PyList_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    }
    else if (PyTuple_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyTuple_GET_SIZE(o);
        if ((!boundscheck) || likely((n >= 0) & (n < PyTuple_GET_SIZE(o)))) {
            PyObject *r = PyTuple_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (PyErr_ExceptionMatches(PyExc_OverflowError))
                        PyErr_Clear();
                    else
                        return NULL;
                }
            }
            return m->sq_item(o, i);
        }
    }
#else
    if (is_list || PySequence_Check(o)) {
        return PySequence_GetItem(o, i);
    }
#endif
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
}

static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *local_type, *local_value, *local_tb;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyThreadState *tstate = PyThreadState_GET();
    local_type = tstate->curexc_type;
    local_value = tstate->curexc_value;
    local_tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#else
    PyErr_Fetch(&local_type, &local_value, &local_tb);
#endif
    PyErr_NormalizeException(&local_type, &local_value, &local_tb);
#if CYTHON_COMPILING_IN_CPYTHON
    if (unlikely(tstate->curexc_type))
#else
    if (unlikely(PyErr_Occurred()))
#endif
        goto bad;
    #if PY_MAJOR_VERSION >= 3
    if (unlikely(PyException_SetTraceback(local_value, local_tb) < 0))
        goto bad;
    #endif
    Py_INCREF(local_type);
    Py_INCREF(local_value);
    Py_INCREF(local_tb);
    *type = local_type;
    *value = local_value;
    *tb = local_tb;
#if CYTHON_COMPILING_IN_CPYTHON
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = local_type;
    tstate->exc_value = local_value;
    tstate->exc_traceback = local_tb;
    /* Make sure tstate is in a consistent state when we XDECREF
       these objects (DECREF may run arbitrary code). */
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(local_type, local_value, local_tb);
#endif
    return 0;
bad:
    *type = 0;
    *value = 0;
    *tb = 0;
    Py_XDECREF(local_type);
    Py_XDECREF(local_value);
    Py_XDECREF(local_tb);
    return -1;
}

static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected) {
    PyErr_Format(PyExc_ValueError,
                 "too many values to unpack (expected %" CYTHON_FORMAT_SSIZE_T "d)", expected);
}

static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index) {
    PyErr_Format(PyExc_ValueError,
                 "need more than %" CYTHON_FORMAT_SSIZE_T "d value%s to unpack",
                 index, (index == 1) ? "" : "s");
}

static CYTHON_INLINE void __Pyx_RaiseNoneNotIterableError(void) {
    PyErr_SetString(PyExc_TypeError, "'NoneType' object is not iterable");
}

static CYTHON_INLINE int __Pyx_IterFinish(void) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyThreadState *tstate = PyThreadState_GET();
    PyObject* exc_type = tstate->curexc_type;
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        if (likely(exc_type == PyExc_StopIteration) || PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration)) {
            PyObject *exc_value, *exc_tb;
            exc_value = tstate->curexc_value;
            exc_tb = tstate->curexc_traceback;
            tstate->curexc_type = 0;
            tstate->curexc_value = 0;
            tstate->curexc_traceback = 0;
            Py_DECREF(exc_type);
            Py_XDECREF(exc_value);
            Py_XDECREF(exc_tb);
            return 0;
        } else {
            return -1;
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    return 0;
#else
    if (unlikely(PyErr_Occurred())) {
        if (likely(PyErr_ExceptionMatches(PyExc_StopIteration))) {
            PyErr_Clear();
            return 0;
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            return -1;
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    }
    return 0;
#endif
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static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected) {
    if (unlikely(retval)) {
        Py_DECREF(retval);
        __Pyx_RaiseTooManyValuesError(expected);
        return -1;
    } else {
        return __Pyx_IterFinish();
    }
    return 0;
}

static CYTHON_INLINE PyObject *__Pyx_GetModuleGlobalName(PyObject *name) {
    PyObject *result;
#if CYTHON_COMPILING_IN_CPYTHON
    result = PyDict_GetItem(__pyx_d, name);
    if (result) {
        Py_INCREF(result);
    } else {
#else
    result = PyObject_GetItem(__pyx_d, name);
    if (!result) {
        PyErr_Clear();
#endif
        result = __Pyx_GetBuiltinName(name);
    }
    return result;
}

static CYTHON_INLINE void __Pyx_ErrRestore(PyObject *type, PyObject *value, PyObject *tb) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyThreadState *tstate = PyThreadState_GET();
    tmp_type = tstate->curexc_type;
    tmp_value = tstate->curexc_value;
    tmp_tb = tstate->curexc_traceback;
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    tstate->curexc_value = value;
    tstate->curexc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_Restore(type, value, tb);
#endif
}
static CYTHON_INLINE void __Pyx_ErrFetch(PyObject **type, PyObject **value, PyObject **tb) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyThreadState *tstate = PyThreadState_GET();
    *type = tstate->curexc_type;
    *value = tstate->curexc_value;
    *tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#else
    PyErr_Fetch(type, value, tb);
#endif
}

static void __Pyx_WriteUnraisable(const char *name, CYTHON_UNUSED int clineno,
                                  CYTHON_UNUSED int lineno, CYTHON_UNUSED const char *filename) {
    PyObject *old_exc, *old_val, *old_tb;
    PyObject *ctx;
    __Pyx_ErrFetch(&old_exc, &old_val, &old_tb);
    #if PY_MAJOR_VERSION < 3
    ctx = PyString_FromString(name);
    #else
    ctx = PyUnicode_FromString(name);
    #endif
    __Pyx_ErrRestore(old_exc, old_val, old_tb);
    if (!ctx) {
        PyErr_WriteUnraisable(Py_None);
    } else {
        PyErr_WriteUnraisable(ctx);
        Py_DECREF(ctx);
    }
}

static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
    if (s1 == s2) {
        return (equals == Py_EQ);
    } else if (PyBytes_CheckExact(s1) & PyBytes_CheckExact(s2)) {
        if (PyBytes_GET_SIZE(s1) != PyBytes_GET_SIZE(s2)) {
            return (equals == Py_NE);
        } else if (PyBytes_GET_SIZE(s1) == 1) {
            if (equals == Py_EQ)
                return (PyBytes_AS_STRING(s1)[0] == PyBytes_AS_STRING(s2)[0]);
            else
                return (PyBytes_AS_STRING(s1)[0] != PyBytes_AS_STRING(s2)[0]);
        } else {
            int result = memcmp(PyBytes_AS_STRING(s1), PyBytes_AS_STRING(s2), (size_t)PyBytes_GET_SIZE(s1));
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & PyBytes_CheckExact(s2)) {
        return (equals == Py_NE);
    } else if ((s2 == Py_None) & PyBytes_CheckExact(s1)) {
        return (equals == Py_NE);
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
#endif
}

static PyObject* __Pyx_PyDict_GetItemDefault(PyObject* d, PyObject* key, PyObject* default_value) {
    PyObject* value;
#if PY_MAJOR_VERSION >= 3
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (unlikely(PyErr_Occurred()))
            return NULL;
        value = default_value;
    }
    Py_INCREF(value);
#else
    if (PyString_CheckExact(key) || PyUnicode_CheckExact(key) || PyInt_CheckExact(key)) {
        value = PyDict_GetItem(d, key);
        if (unlikely(!value)) {
            value = default_value;
        }
        Py_INCREF(value);
    } else {
        if (default_value == Py_None)
            default_value = NULL;
        value = PyObject_CallMethodObjArgs(
            d, __pyx_n_s__get, key, default_value, NULL);
    }
#endif
    return value;
}

static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type) {
    if (unlikely(!type)) {
        PyErr_Format(PyExc_SystemError, "Missing type object");
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    }
    if (likely(PyObject_TypeCheck(obj, type)))
        return 1;
    PyErr_Format(PyExc_TypeError, "Cannot convert %.200s to %.200s",
                 Py_TYPE(obj)->tp_name, type->tp_name);
    return 0;
}

#if PY_MAJOR_VERSION >= 3
static CYTHON_INLINE PyObject* __Pyx_PyDict_Values(PyObject* d) {
    return PyObject_CallMethodObjArgs(d, __pyx_n_s__values, NULL);
}
#endif

static int __Pyx_SetVtable(PyObject *dict, void *vtable) {
#if PY_VERSION_HEX >= 0x02070000 && !(PY_MAJOR_VERSION==3&&PY_MINOR_VERSION==0)
    PyObject *ob = PyCapsule_New(vtable, 0, 0);
#else
    PyObject *ob = PyCObject_FromVoidPtr(vtable, 0);
#endif
    if (!ob)
        goto bad;
    if (PyDict_SetItem(dict, __pyx_n_s____pyx_vtable__, ob) < 0)
        goto bad;
    Py_DECREF(ob);
    return 0;
bad:
    Py_XDECREF(ob);
    return -1;
}

static void* __Pyx_GetVtable(PyObject *dict) {
    void* ptr;
    PyObject *ob = PyObject_GetItem(dict, __pyx_n_s____pyx_vtable__);
    if (!ob)
        goto bad;
#if PY_VERSION_HEX >= 0x02070000 && !(PY_MAJOR_VERSION==3&&PY_MINOR_VERSION==0)
    ptr = PyCapsule_GetPointer(ob, 0);
#else
    ptr = PyCObject_AsVoidPtr(ob);
#endif
    if (!ptr && !PyErr_Occurred())
        PyErr_SetString(PyExc_RuntimeError, "invalid vtable found for imported type");
    Py_DECREF(ob);
    return ptr;
bad:
    Py_XDECREF(ob);
    return NULL;
}

static CYTHON_INLINE void __Pyx_ExceptionSave(PyObject **type, PyObject **value, PyObject **tb) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyThreadState *tstate = PyThreadState_GET();
    *type = tstate->exc_type;
    *value = tstate->exc_value;
    *tb = tstate->exc_traceback;
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
#else
    PyErr_GetExcInfo(type, value, tb);
#endif
}
static void __Pyx_ExceptionReset(PyObject *type, PyObject *value, PyObject *tb) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyThreadState *tstate = PyThreadState_GET();
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = type;
    tstate->exc_value = value;
    tstate->exc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(type, value, tb);
#endif
}

static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *empty_list = 0;
    PyObject *module = 0;
    PyObject *global_dict = 0;
    PyObject *empty_dict = 0;
    PyObject *list;
    #if PY_VERSION_HEX < 0x03030000
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s____import__);
    if (!py_import)
        goto bad;
    #endif
    if (from_list)
        list = from_list;
    else {
        empty_list = PyList_New(0);
        if (!empty_list)
            goto bad;
        list = empty_list;
    }
    global_dict = PyModule_GetDict(__pyx_m);
    if (!global_dict)
        goto bad;
    empty_dict = PyDict_New();
    if (!empty_dict)
        goto bad;
    #if PY_VERSION_HEX >= 0x02050000
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if (strchr(__Pyx_MODULE_NAME, '.')) {
                #if PY_VERSION_HEX < 0x03030000
                PyObject *py_level = PyInt_FromLong(1);
                if (!py_level)
                    goto bad;
                module = PyObject_CallFunctionObjArgs(py_import,
                    name, global_dict, empty_dict, list, py_level, NULL);
                Py_DECREF(py_level);
                #else
                module = PyImport_ImportModuleLevelObject(
                    name, global_dict, empty_dict, list, 1);
                #endif
                if (!module) {
                    if (!PyErr_ExceptionMatches(PyExc_ImportError))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0; /* try absolute import on failure */
        }
        #endif
        if (!module) {
            #if PY_VERSION_HEX < 0x03030000
            PyObject *py_level = PyInt_FromLong(level);
            if (!py_level)
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, global_dict, empty_dict, list, py_level, NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, global_dict, empty_dict, list, level);
            #endif
        }
    }
    #else
    if (level>0) {
        PyErr_SetString(PyExc_RuntimeError, "Relative import is not supported for Python <=2.4.");
        goto bad;
    }
    module = PyObject_CallFunctionObjArgs(py_import,
        name, global_dict, empty_dict, list, NULL);
    #endif
bad:
    #if PY_VERSION_HEX < 0x03030000
    Py_XDECREF(py_import);
    #endif
    Py_XDECREF(empty_list);
    Py_XDECREF(empty_dict);
    return module;
}

static CYTHON_INLINE unsigned char __Pyx_PyInt_AsUnsignedChar(PyObject* x) {
    const unsigned char neg_one = (unsigned char)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(unsigned char) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(unsigned char)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to unsigned char" :
                    "value too large to convert to unsigned char");
            }
            return (unsigned char)-1;
        }
        return (unsigned char)val;
    }
    return (unsigned char)__Pyx_PyInt_AsUnsignedLong(x);
}

static CYTHON_INLINE unsigned short __Pyx_PyInt_AsUnsignedShort(PyObject* x) {
    const unsigned short neg_one = (unsigned short)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(unsigned short) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(unsigned short)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to unsigned short" :
                    "value too large to convert to unsigned short");
            }
            return (unsigned short)-1;
        }
        return (unsigned short)val;
    }
    return (unsigned short)__Pyx_PyInt_AsUnsignedLong(x);
}

static CYTHON_INLINE unsigned int __Pyx_PyInt_AsUnsignedInt(PyObject* x) {
    const unsigned int neg_one = (unsigned int)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(unsigned int) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(unsigned int)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to unsigned int" :
                    "value too large to convert to unsigned int");
            }
            return (unsigned int)-1;
        }
        return (unsigned int)val;
    }
    return (unsigned int)__Pyx_PyInt_AsUnsignedLong(x);
}

static CYTHON_INLINE char __Pyx_PyInt_AsChar(PyObject* x) {
    const char neg_one = (char)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(char) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(char)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to char" :
                    "value too large to convert to char");
            }
            return (char)-1;
        }
        return (char)val;
    }
    return (char)__Pyx_PyInt_AsLong(x);
}

static CYTHON_INLINE short __Pyx_PyInt_AsShort(PyObject* x) {
    const short neg_one = (short)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(short) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(short)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to short" :
                    "value too large to convert to short");
            }
            return (short)-1;
        }
        return (short)val;
    }
    return (short)__Pyx_PyInt_AsLong(x);
}

static CYTHON_INLINE int __Pyx_PyInt_AsInt(PyObject* x) {
    const int neg_one = (int)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(int) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(int)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to int" :
                    "value too large to convert to int");
            }
            return (int)-1;
        }
        return (int)val;
    }
    return (int)__Pyx_PyInt_AsLong(x);
}

static CYTHON_INLINE signed char __Pyx_PyInt_AsSignedChar(PyObject* x) {
    const signed char neg_one = (signed char)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(signed char) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(signed char)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to signed char" :
                    "value too large to convert to signed char");
            }
            return (signed char)-1;
        }
        return (signed char)val;
    }
    return (signed char)__Pyx_PyInt_AsSignedLong(x);
}

static CYTHON_INLINE signed short __Pyx_PyInt_AsSignedShort(PyObject* x) {
    const signed short neg_one = (signed short)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(signed short) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(signed short)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to signed short" :
                    "value too large to convert to signed short");
            }
            return (signed short)-1;
        }
        return (signed short)val;
    }
    return (signed short)__Pyx_PyInt_AsSignedLong(x);
}

static CYTHON_INLINE signed int __Pyx_PyInt_AsSignedInt(PyObject* x) {
    const signed int neg_one = (signed int)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(signed int) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(signed int)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to signed int" :
                    "value too large to convert to signed int");
            }
            return (signed int)-1;
        }
        return (signed int)val;
    }
    return (signed int)__Pyx_PyInt_AsSignedLong(x);
}

static CYTHON_INLINE int __Pyx_PyInt_AsLongDouble(PyObject* x) {
    const int neg_one = (int)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
    if (sizeof(int) < sizeof(long)) {
        long val = __Pyx_PyInt_AsLong(x);
        if (unlikely(val != (long)(int)val)) {
            if (!unlikely(val == -1 && PyErr_Occurred())) {
                PyErr_SetString(PyExc_OverflowError,
                    (is_unsigned && unlikely(val < 0)) ?
                    "can't convert negative value to int" :
                    "value too large to convert to int");
            }
            return (int)-1;
        }
        return (int)val;
    }
    return (int)__Pyx_PyInt_AsLong(x);
}

#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
#include "longintrepr.h"
#endif
#endif
static CYTHON_INLINE unsigned long __Pyx_PyInt_AsUnsignedLong(PyObject* x) {
    const unsigned long neg_one = (unsigned long)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        long val = PyInt_AS_LONG(x);
        if (is_unsigned && unlikely(val < 0)) {
            PyErr_SetString(PyExc_OverflowError,
                            "can't convert negative value to unsigned long");
            return (unsigned long)-1;
        }
        return (unsigned long)val;
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(unsigned long)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return (unsigned long) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            if (unlikely(Py_SIZE(x) < 0)) {
                PyErr_SetString(PyExc_OverflowError,
                                "can't convert negative value to unsigned long");
                return (unsigned long)-1;
            }
            return (unsigned long)PyLong_AsUnsignedLong(x);
        } else {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(unsigned long)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return +(unsigned long) ((PyLongObject*)x)->ob_digit[0];
                    case -1: return -(unsigned long) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            return (unsigned long)PyLong_AsLong(x);
        }
    } else {
        unsigned long val;
        PyObject *tmp = __Pyx_PyNumber_Int(x);
        if (!tmp) return (unsigned long)-1;
        val = __Pyx_PyInt_AsUnsignedLong(tmp);
        Py_DECREF(tmp);
        return val;
    }
}

#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
#include "longintrepr.h"
#endif
#endif
static CYTHON_INLINE unsigned PY_LONG_LONG __Pyx_PyInt_AsUnsignedLongLong(PyObject* x) {
    const unsigned PY_LONG_LONG neg_one = (unsigned PY_LONG_LONG)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        long val = PyInt_AS_LONG(x);
        if (is_unsigned && unlikely(val < 0)) {
            PyErr_SetString(PyExc_OverflowError,
                            "can't convert negative value to unsigned PY_LONG_LONG");
            return (unsigned PY_LONG_LONG)-1;
        }
        return (unsigned PY_LONG_LONG)val;
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(unsigned PY_LONG_LONG)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return (unsigned PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            if (unlikely(Py_SIZE(x) < 0)) {
                PyErr_SetString(PyExc_OverflowError,
                                "can't convert negative value to unsigned PY_LONG_LONG");
                return (unsigned PY_LONG_LONG)-1;
            }
            return (unsigned PY_LONG_LONG)PyLong_AsUnsignedLongLong(x);
        } else {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(unsigned PY_LONG_LONG)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return +(unsigned PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                    case -1: return -(unsigned PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            return (unsigned PY_LONG_LONG)PyLong_AsLongLong(x);
        }
    } else {
        unsigned PY_LONG_LONG val;
        PyObject *tmp = __Pyx_PyNumber_Int(x);
        if (!tmp) return (unsigned PY_LONG_LONG)-1;
        val = __Pyx_PyInt_AsUnsignedLongLong(tmp);
        Py_DECREF(tmp);
        return val;
    }
}

#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
#include "longintrepr.h"
#endif
#endif
static CYTHON_INLINE long __Pyx_PyInt_AsLong(PyObject* x) {
    const long neg_one = (long)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        long val = PyInt_AS_LONG(x);
        if (is_unsigned && unlikely(val < 0)) {
            PyErr_SetString(PyExc_OverflowError,
                            "can't convert negative value to long");
            return (long)-1;
        }
        return (long)val;
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(long)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return (long) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            if (unlikely(Py_SIZE(x) < 0)) {
                PyErr_SetString(PyExc_OverflowError,
                                "can't convert negative value to long");
                return (long)-1;
            }
            return (long)PyLong_AsUnsignedLong(x);
        } else {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(long)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return +(long) ((PyLongObject*)x)->ob_digit[0];
                    case -1: return -(long) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            return (long)PyLong_AsLong(x);
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_Int(x);
        if (!tmp) return (long)-1;
        val = __Pyx_PyInt_AsLong(tmp);
        Py_DECREF(tmp);
        return val;
    }
}

#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
#include "longintrepr.h"
#endif
#endif
static CYTHON_INLINE PY_LONG_LONG __Pyx_PyInt_AsLongLong(PyObject* x) {
    const PY_LONG_LONG neg_one = (PY_LONG_LONG)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        long val = PyInt_AS_LONG(x);
        if (is_unsigned && unlikely(val < 0)) {
            PyErr_SetString(PyExc_OverflowError,
                            "can't convert negative value to PY_LONG_LONG");
            return (PY_LONG_LONG)-1;
        }
        return (PY_LONG_LONG)val;
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(PY_LONG_LONG)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return (PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            if (unlikely(Py_SIZE(x) < 0)) {
                PyErr_SetString(PyExc_OverflowError,
                                "can't convert negative value to PY_LONG_LONG");
                return (PY_LONG_LONG)-1;
            }
            return (PY_LONG_LONG)PyLong_AsUnsignedLongLong(x);
        } else {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(PY_LONG_LONG)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return +(PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                    case -1: return -(PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            return (PY_LONG_LONG)PyLong_AsLongLong(x);
        }
    } else {
        PY_LONG_LONG val;
        PyObject *tmp = __Pyx_PyNumber_Int(x);
        if (!tmp) return (PY_LONG_LONG)-1;
        val = __Pyx_PyInt_AsLongLong(tmp);
        Py_DECREF(tmp);
        return val;
    }
}

#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
#include "longintrepr.h"
#endif
#endif
static CYTHON_INLINE signed long __Pyx_PyInt_AsSignedLong(PyObject* x) {
    const signed long neg_one = (signed long)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        long val = PyInt_AS_LONG(x);
        if (is_unsigned && unlikely(val < 0)) {
            PyErr_SetString(PyExc_OverflowError,
                            "can't convert negative value to signed long");
            return (signed long)-1;
        }
        return (signed long)val;
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(signed long)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return (signed long) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            if (unlikely(Py_SIZE(x) < 0)) {
                PyErr_SetString(PyExc_OverflowError,
                                "can't convert negative value to signed long");
                return (signed long)-1;
            }
            return (signed long)PyLong_AsUnsignedLong(x);
        } else {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(signed long)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return +(signed long) ((PyLongObject*)x)->ob_digit[0];
                    case -1: return -(signed long) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            return (signed long)PyLong_AsLong(x);
        }
    } else {
        signed long val;
        PyObject *tmp = __Pyx_PyNumber_Int(x);
        if (!tmp) return (signed long)-1;
        val = __Pyx_PyInt_AsSignedLong(tmp);
        Py_DECREF(tmp);
        return val;
    }
}

#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
#include "longintrepr.h"
#endif
#endif
static CYTHON_INLINE signed PY_LONG_LONG __Pyx_PyInt_AsSignedLongLong(PyObject* x) {
    const signed PY_LONG_LONG neg_one = (signed PY_LONG_LONG)-1, const_zero = 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        long val = PyInt_AS_LONG(x);
        if (is_unsigned && unlikely(val < 0)) {
            PyErr_SetString(PyExc_OverflowError,
                            "can't convert negative value to signed PY_LONG_LONG");
            return (signed PY_LONG_LONG)-1;
        }
        return (signed PY_LONG_LONG)val;
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(signed PY_LONG_LONG)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return (signed PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            if (unlikely(Py_SIZE(x) < 0)) {
                PyErr_SetString(PyExc_OverflowError,
                                "can't convert negative value to signed PY_LONG_LONG");
                return (signed PY_LONG_LONG)-1;
            }
            return (signed PY_LONG_LONG)PyLong_AsUnsignedLongLong(x);
        } else {
#if CYTHON_COMPILING_IN_CPYTHON && PY_MAJOR_VERSION >= 3
#if CYTHON_USE_PYLONG_INTERNALS
            if (sizeof(digit) <= sizeof(signed PY_LONG_LONG)) {
                switch (Py_SIZE(x)) {
                    case  0: return 0;
                    case  1: return +(signed PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                    case -1: return -(signed PY_LONG_LONG) ((PyLongObject*)x)->ob_digit[0];
                }
            }
#endif
#endif
            return (signed PY_LONG_LONG)PyLong_AsLongLong(x);
        }
    } else {
        signed PY_LONG_LONG val;
        PyObject *tmp = __Pyx_PyNumber_Int(x);
        if (!tmp) return (signed PY_LONG_LONG)-1;
        val = __Pyx_PyInt_AsSignedLongLong(tmp);
        Py_DECREF(tmp);
        return val;
    }
}

static int __Pyx_check_binary_version(void) {
    char ctversion[4], rtversion[4];
    PyOS_snprintf(ctversion, 4, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    PyOS_snprintf(rtversion, 4, "%s", Py_GetVersion());
    if (ctversion[0] != rtversion[0] || ctversion[2] != rtversion[2]) {
        char message[200];
        PyOS_snprintf(message, sizeof(message),
                      "compiletime version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        #if PY_VERSION_HEX < 0x02050000
        return PyErr_Warn(NULL, message);
        #else
        return PyErr_WarnEx(NULL, message, 1);
        #endif
    }
    return 0;
}

static int __Pyx_ExportVoidPtr(PyObject *name, void *p, const char *sig) {
    PyObject *d;
    PyObject *cobj = 0;
    d = PyDict_GetItem(__pyx_d, __pyx_n_s____pyx_capi__);
    Py_XINCREF(d);
    if (!d) {
        d = PyDict_New();
        if (!d)
            goto bad;
        if (__Pyx_PyObject_SetAttrStr(__pyx_m, __pyx_n_s____pyx_capi__, d) < 0)
            goto bad;
    }
#if PY_VERSION_HEX >= 0x02070000 && !(PY_MAJOR_VERSION==3 && PY_MINOR_VERSION==0)
    cobj = PyCapsule_New(p, sig, 0);
#else
    cobj = PyCObject_FromVoidPtrAndDesc(p, (void *)sig, 0);
#endif
    if (!cobj)
        goto bad;
    if (PyDict_SetItem(d, name, cobj) < 0)
        goto bad;
    Py_DECREF(cobj);
    Py_DECREF(d);
    return 0;
bad:
    Py_XDECREF(cobj);
    Py_XDECREF(d);
    return -1;
}

#ifndef __PYX_HAVE_RT_ImportModule
#define __PYX_HAVE_RT_ImportModule
static PyObject *__Pyx_ImportModule(const char *name) {
    PyObject *py_name = 0;
    PyObject *py_module = 0;
    py_name = __Pyx_PyIdentifier_FromString(name);
    if (!py_name)
        goto bad;
    py_module = PyImport_Import(py_name);
    Py_DECREF(py_name);
    return py_module;
bad:
    Py_XDECREF(py_name);
    return 0;
}
#endif

#ifndef __PYX_HAVE_RT_ImportType
#define __PYX_HAVE_RT_ImportType
static PyTypeObject *__Pyx_ImportType(const char *module_name, const char *class_name,
    size_t size, int strict)
{
    PyObject *py_module = 0;
    PyObject *result = 0;
    PyObject *py_name = 0;
    char warning[200];
    Py_ssize_t basicsize;
#ifdef Py_LIMITED_API
    PyObject *py_basicsize;
#endif
    py_module = __Pyx_ImportModule(module_name);
    if (!py_module)
        goto bad;
    py_name = __Pyx_PyIdentifier_FromString(class_name);
    if (!py_name)
        goto bad;
    result = PyObject_GetAttr(py_module, py_name);
    Py_DECREF(py_name);
    py_name = 0;
    Py_DECREF(py_module);
    py_module = 0;
    if (!result)
        goto bad;
    if (!PyType_Check(result)) {
        PyErr_Format(PyExc_TypeError,
            "%s.%s is not a type object",
            module_name, class_name);
        goto bad;
    }
#ifndef Py_LIMITED_API
    basicsize = ((PyTypeObject *)result)->tp_basicsize;
#else
    py_basicsize = PyObject_GetAttrString(result, "__basicsize__");
    if (!py_basicsize)
        goto bad;
    basicsize = PyLong_AsSsize_t(py_basicsize);
    Py_DECREF(py_basicsize);
    py_basicsize = 0;
    if (basicsize == (Py_ssize_t)-1 && PyErr_Occurred())
        goto bad;
#endif
    if (!strict && (size_t)basicsize > size) {
        PyOS_snprintf(warning, sizeof(warning),
            "%s.%s size changed, may indicate binary incompatibility",
            module_name, class_name);
        #if PY_VERSION_HEX < 0x02050000
        if (PyErr_Warn(NULL, warning) < 0) goto bad;
        #else
        if (PyErr_WarnEx(NULL, warning, 0) < 0) goto bad;
        #endif
    }
    else if ((size_t)basicsize != size) {
        PyErr_Format(PyExc_ValueError,
            "%s.%s has the wrong size, try recompiling",
            module_name, class_name);
        goto bad;
    }
    return (PyTypeObject *)result;
bad:
    Py_XDECREF(py_module);
    Py_XDECREF(result);
    return NULL;
}
#endif

#ifndef __PYX_HAVE_RT_ImportFunction
#define __PYX_HAVE_RT_ImportFunction
static int __Pyx_ImportFunction(PyObject *module, const char *funcname, void (**f)(void), const char *sig) {
    PyObject *d = 0;
    PyObject *cobj = 0;
    union {
        void (*fp)(void);
        void *p;
    } tmp;
    d = PyObject_GetAttrString(module, (char *)"__pyx_capi__");
    if (!d)
        goto bad;
    cobj = PyDict_GetItemString(d, funcname);
    if (!cobj) {
        PyErr_Format(PyExc_ImportError,
            "%s does not export expected C function %s",
                PyModule_GetName(module), funcname);
        goto bad;
    }
#if PY_VERSION_HEX >= 0x02070000 && !(PY_MAJOR_VERSION==3 && PY_MINOR_VERSION==0)
    if (!PyCapsule_IsValid(cobj, sig)) {
        PyErr_Format(PyExc_TypeError,
            "C function %s.%s has wrong signature (expected %s, got %s)",
             PyModule_GetName(module), funcname, sig, PyCapsule_GetName(cobj));
        goto bad;
    }
    tmp.p = PyCapsule_GetPointer(cobj, sig);
#else
    {const char *desc, *s1, *s2;
    desc = (const char *)PyCObject_GetDesc(cobj);
    if (!desc)
        goto bad;
    s1 = desc; s2 = sig;
    while (*s1 != '\0' && *s1 == *s2) { s1++; s2++; }
    if (*s1 != *s2) {
        PyErr_Format(PyExc_TypeError,
            "C function %s.%s has wrong signature (expected %s, got %s)",
             PyModule_GetName(module), funcname, sig, desc);
        goto bad;
    }
    tmp.p = PyCObject_AsVoidPtr(cobj);}
#endif
    *f = tmp.fp;
    if (!(*f))
        goto bad;
    Py_DECREF(d);
    return 0;
bad:
    Py_XDECREF(d);
    return -1;
}
#endif

static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = (start + end) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, new_max*sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}

#include "compile.h"
#include "frameobject.h"
#include "traceback.h"
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_srcfile = 0;
    PyObject *py_funcname = 0;
    #if PY_MAJOR_VERSION < 3
    py_srcfile = PyString_FromString(filename);
    #else
    py_srcfile = PyUnicode_FromString(filename);
    #endif
    if (!py_srcfile) goto bad;
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        #else
        py_funcname = PyUnicode_FromString(funcname);
        #endif
    }
    if (!py_funcname) goto bad;
    py_code = __Pyx_PyCode_New(
        0,            /*int argcount,*/
        0,            /*int kwonlyargcount,*/
        0,            /*int nlocals,*/
        0,            /*int stacksize,*/
        0,            /*int flags,*/
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,      /*int firstlineno,*/
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    Py_DECREF(py_funcname);
    return py_code;
bad:
    Py_XDECREF(py_srcfile);
    Py_XDECREF(py_funcname);
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_globals = 0;
    PyFrameObject *py_frame = 0;
    py_code = __pyx_find_code_object(c_line ? c_line : py_line);
    if (!py_code) {
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) goto bad;
        __pyx_insert_code_object(c_line ? c_line : py_line, py_code);
    }
    py_globals = PyModule_GetDict(__pyx_m);
    if (!py_globals) goto bad;
    py_frame = PyFrame_New(
        PyThreadState_GET(), /*PyThreadState *tstate,*/
        py_code,             /*PyCodeObject *code,*/
        py_globals,          /*PyObject *globals,*/
        0                    /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    py_frame->f_lineno = py_line;
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}

static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION < 3
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        #else  /* Python 3+ has unicode identifiers */
        if (t->is_unicode | t->is_str) {
            if (t->intern) {
                *t->p = PyUnicode_InternFromString(t->s);
            } else if (t->encoding) {
                *t->p = PyUnicode_Decode(t->s, t->n - 1, t->encoding, NULL);
            } else {
                *t->p = PyUnicode_FromStringAndSize(t->s, t->n - 1);
            }
        } else {
            *t->p = PyBytes_FromStringAndSize(t->s, t->n - 1);
        }
        #endif
        if (!*t->p)
            return -1;
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, strlen(c_str));
}
static CYTHON_INLINE char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
static CYTHON_INLINE char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
#if PY_VERSION_HEX < 0x03030000
        char* defenc_c;
        PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
        if (!defenc) return NULL;
        defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
        {
            char* end = defenc_c + PyBytes_GET_SIZE(defenc);
            char* c;
            for (c = defenc_c; c < end; c++) {
                if ((unsigned char) (*c) >= 128) {
                    PyUnicode_AsASCIIString(o);
                    return NULL;
                }
            }
        }
#endif /*__PYX_DEFAULT_STRING_ENCODING_IS_ASCII*/
        *length = PyBytes_GET_SIZE(defenc);
        return defenc_c;
#else /* PY_VERSION_HEX < 0x03030000 */
        if (PyUnicode_READY(o) == -1) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
        if (PyUnicode_IS_ASCII(o)) {
            *length = PyUnicode_GET_DATA_SIZE(o);
            return PyUnicode_AsUTF8(o);
        } else {
            PyUnicode_AsASCIIString(o);
            return NULL;
        }
#else /* __PYX_DEFAULT_STRING_ENCODING_IS_ASCII */
        return PyUnicode_AsUTF8AndSize(o, length);
#endif /* __PYX_DEFAULT_STRING_ENCODING_IS_ASCII */
#endif /* PY_VERSION_HEX < 0x03030000 */
    } else
#endif /* __PYX_DEFAULT_STRING_ENCODING_IS_ASCII  || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT */
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (r < 0) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_Int(PyObject* x) {
  PyNumberMethods *m;
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (PyInt_Check(x) || PyLong_Check(x))
#else
  if (PyLong_Check(x))
#endif
    return Py_INCREF(x), x;
  m = Py_TYPE(x)->tp_as_number;
#if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = PyNumber_Int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = PyNumber_Long(x);
  }
#else
  if (m && m->nb_int) {
    name = "int";
    res = PyNumber_Long(x);
  }
#endif
  if (res) {
#if PY_MAJOR_VERSION < 3
    if (!PyInt_Check(res) && !PyLong_Check(res)) {
#else
    if (!PyLong_Check(res)) {
#endif
      PyErr_Format(PyExc_TypeError,
                   "__%s__ returned non-%s (type %.200s)",
                   name, name, Py_TYPE(res)->tp_name);
      Py_DECREF(res);
      return NULL;
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject* x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
#if PY_VERSION_HEX < 0x02050000
   if (ival <= LONG_MAX)
       return PyInt_FromLong((long)ival);
   else {
       unsigned char *bytes = (unsigned char *) &ival;
       int one = 1; int little = (int)*(unsigned char*)&one;
       return _PyLong_FromByteArray(bytes, sizeof(size_t), little, 0);
   }
#else
   return PyInt_FromSize_t(ival);
#endif
}
static CYTHON_INLINE size_t __Pyx_PyInt_AsSize_t(PyObject* x) {
   unsigned PY_LONG_LONG val = __Pyx_PyInt_AsUnsignedLongLong(x);
   if (unlikely(val != (unsigned PY_LONG_LONG)(size_t)val)) {
       if ((val != (unsigned PY_LONG_LONG)-1) || !PyErr_Occurred())
           PyErr_SetString(PyExc_OverflowError,
                           "value too large to convert to size_t");
       return (size_t)-1;
   }
   return (size_t)val;
}


#endif /* Py_PYTHON_H */
