# The MEME Suite

## Motif-based sequence analysis tools

## dust

### Usage:

`dust <sequence file> <cutoff>`

### Description

Dust masks low-compexity regions in sequences in a FASTA sequence file This is recommended in order to prevent such low-complexity regions from distorting the search for motifs, and in motif enrichment analyses using AME. Dust was written by R. Tatusov and D.J. Lipman (unpublished).

### Input

#### Sequence File

A file containing FASTA formatted sequences.

#### Cutoff

The minimum score for masking low-complexity regions in sequences. By default, the cutoff score is 20. Making the cutoff lower will cause more masking of low-complexity regions.

### Output

Dust outputs a FASTA file where all low-complexity regions are changed to runs of the `N` character.