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MAST - Motif Alignment and Search Tool
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	MAST version 5.1.1 (Release date: Wed Jan 29 15:00:42 2020 -0800)

	For further information on how to interpret these results please access http://meme-suite.org/.
	To get a copy of the MAST software please access http://meme-suite.org.
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REFERENCE
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	If you use this program in your research, please cite:

	Timothy L. Bailey and Michael Gribskov,
	"Combining evidence using p-values: application to sequence homology
	searches", Bioinformatics, 14(48-54), 1998.
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DATABASE AND MOTIFS
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	DATABASE sequences.fa (peptide)
	Last updated on Wed Feb  5 22:58:41 2020
	Database contains 12 sequences, 1093 residues

	MOTIFS meme.xml (peptide)
	MOTIF ID                                       ALT ID WIDTH BEST POSSIBLE MATCH
	----- ---------------------------------------- ------ ----- -------------------
	    1 YGZTLITKTREGIDRSERS                      MEME-1    19 YCQTLITKTREGVDRSEHS
	    2 NQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDESGEP MEME-2    40 NQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDEGGEP
	    3 MKQKNPILYFR                              MEME-3    11 MKQKNPILYFR

	PAIRWISE MOTIF CORRELATIONS:
	MOTIF     1     2
	----- ----- -----
	   2   0.31
	   3   0.22  0.57
	No overly similar pairs (correlation > 0.60) found.

	Random model letter frequencies (from non-redundant database):
	A 0.073 C 0.018 D 0.052 E 0.062 F 0.040 G 0.069 H 0.022 I 0.056 K 0.058 
	L 0.092 M 0.023 N 0.046 P 0.051 Q 0.041 R 0.052 S 0.074 T 0.059 V 0.064 
	W 0.013 Y 0.033 
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********************************************************************************
SECTION I: HIGH-SCORING SEQUENCES
********************************************************************************
	- Each of the following 12 sequences has E-value less than 10.
	- The E-value of a sequence is the expected number of sequences
	  in a random database of the same size that would match the motifs as
	  well as the sequence does and is equal to the combined p-value of the
	  sequence times the number of sequences in the database.
	- The combined p-value of a sequence measures the strength of the
	  match of the sequence to all the motifs and is calculated by
	    o finding the score of the single best match of each motif
	      to the sequence (best matches may overlap),
	    o calculating the sequence p-value of each score,
	    o forming the product of the p-values,
	    o taking the p-value of the product.
	- The sequence p-value of a score is defined as the
	  probability of a random sequence of the same length containing
	  some match with as good or better a score.
	- The score for the match of a position in a sequence to a motif
	  is computed by by summing the appropriate entry from each column of
	  the position-dependent scoring matrix that represents the motif.
	- Sequences shorter than one or more of the motifs are skipped.
	- The table is sorted by increasing E-value.
********************************************************************************

SEQUENCE NAME                      DESCRIPTION                   E-VALUE  LENGTH
-------------                      -----------                   -------- ------
449                                                               7.2e-66    159
451                                                               1.1e-64    159
450                                                               8.6e-40    160
454                                                               6.9e-36     99
448                                                               2.3e-24     64
444                                                               7.7e-24     65
445                                                               2.3e-22     62
447                                                               1.5e-21     62
452                                                               5.3e-21     69
446                                                               2.8e-20     65
443                                                               6.4e-17     58
453                                                               1.9e-16     71

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********************************************************************************
SECTION II: MOTIF DIAGRAMS
********************************************************************************
	- The ordering and spacing of all non-overlapping motif occurrences
	  are shown for each high-scoring sequence listed in Section I.
	- A motif occurrence is defined as a position in the sequence whose
	  match to the motif has POSITION p-value less than 0.0001.
	- The POSITION p-value of a match is the probability of
	  a single random subsequence of the length of the motif
	  scoring at least as well as the observed match.
	- For each sequence, all motif occurrences are shown unless there
	  are overlaps.  In that case, a motif occurrence is shown only if its
	  p-value is less than the product of the p-values of the other
	  (lower-numbered) motif occurrences that it overlaps.
	- The table also shows the E-value of each sequence.
	- Spacers and motif occurences are indicated by
	   o -d-    `d' residues separate the end of the preceding motif 
		    occurrence and the start of the following motif occurrence
	   o [n]  occurrence of motif `n' with p-value less than 0.0001.
********************************************************************************

SEQUENCE NAME                      E-VALUE   MOTIF DIAGRAM
-------------                      --------  -------------
454                                 6.9e-36  1-[2]-13-[1]-6-[1]-1
448                                 2.3e-24  [3]-32-[1]-2
444                                 7.7e-24  [3]-34-[1]-1
445                                 2.3e-22  [3]-31-[1]-1
452                                 5.3e-21  [3]-38-[1]-1
446                                 2.8e-20  [3]-34-[1]-1

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********************************************************************************
SECTION III: ANNOTATED SEQUENCES
********************************************************************************
	- The positions and p-values of the non-overlapping motif occurrences
	  are shown above the actual sequence for each of the high-scoring
	  sequences from Section I.
	- A motif occurrence is defined as a position in the sequence whose
	  match to the motif has POSITION p-value less than 0.0001 as 
	  defined in Section II.
	- For each sequence, the first line specifies the name of the sequence.
	- The second (and possibly more) lines give a description of the 
	  sequence.
	- Following the description line(s) is a line giving the length, 
	  combined p-value, and E-value of the sequence as defined in Section I.
	- The next line reproduces the motif diagram from Section II.
	- The entire sequence is printed on the following lines.
	- Motif occurrences are indicated directly above their positions in the
	  sequence on lines showing
	   o the motif number of the occurrence,
	   o the position p-value of the occurrence,
	   o the best possible match to the motif, and
	   o columns whose match to the motif has a positive score (indicated 
	     by a plus sign).
********************************************************************************


449
  LENGTH = 159  COMBINED P-VALUE = 6.01e-67  E-VALUE =  7.2e-66

      [2]                                                  [1]
      2.5e-51                                              1.1e-18
      NQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDEGGEP             YCQTLITKTREGVDRSEHS
      ++++++++++++++++++++++++++++++++++++++++             +++++++++++++++++++
1    MNQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDESGEPLIRKYIESSSLSGRTETLITKTREGIDRSERSRG

            [1]                              [1]                      [1]
            5.6e-18                          5.5e-20                  8.3e-17
            YCQTLITKTREGVDRSEHS              YCQTLITKTREGVDRSEHS      YCQTLITKTR
            +++++++++++++++++++              +++++++++++++++++++      +++++ ++++
76   IENNLSFADKTLITETREGIDRSEKGYGYDANMQENEMNAFGETLITRTREGVDRSERSSNDDNLVFQTIATFTR

     
     
     EGVDRSEHS
     +++++++++
151  ESIDRSEKS


451
  LENGTH = 159  COMBINED P-VALUE = 9.37e-66  E-VALUE =  1.1e-64

      [2]                                                  [1]
      2.5e-51                                              1.1e-18
      NQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDEGGEP             YCQTLITKTREGVDRSEHS
      ++++++++++++++++++++++++++++++++++++++++             +++++++++++++++++++
1    MNQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDESGEPFIRKYIESSSLSGRTETLITKTREGIDRSERSRG

            [1]                              [1]                      [1]
            3.8e-15                          8.8e-19                  8.7e-16
            YCQTLITKTREGVDRSEHS              YCQTLITKTREGVDRSEHS      YCQTLITKTR
            +++++++++ ++++ ++++              +++++++++++++++++++      +++++ ++++
76   IENNLSFADKTLITETKEGIDKSEKGYGYDENMQENKMNAFGETLITRTREGIDRAERSGSSDNLLFQTITTFTR

     
     
     EGVDRSEHS
     +++++++++
151  ESIDRSEKS


450
  LENGTH = 160  COMBINED P-VALUE = 7.20e-41  E-VALUE =  8.6e-40

     [2]                                                 [1]
     3.3e-30                                             3.2e-19
     NQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDEGGEP            YCQTLITKTREGVDRSEHS
     ++++++++++++++++++++++++++++++++++  ++++            +++++++++++++++++++
1    MQKSPLLYYRMECEKGDSTNFQEVDYDFISGLWNINGQPLIKKYIENKGIEEKCQTLITETRESIDRSEGSCYDM

         [1]                              [1]                          [1]
         2.0e-16                          6.8e-17                      1.6e-17
         YCQTLITKTREGVDRSEHS              YCQTLITKTREGVDRSEHS          YCQTLITKT
         ++++ ++++++++++++++              +++++ +++++++ +++++          +++ +++++
76   QSLEIDKTTITATREGIDRSEQSVSENLSNEIMNFNNVGETLLTKTREGIYRSEGSMGNTNDETISLHQSLITFT

     
     
     REGVDRSEHS
     ++++++++++
151  RESIDRSEQS


454
  LENGTH = 99  COMBINED P-VALUE = 5.72e-37  E-VALUE =  6.9e-36
  DIAGRAM: 1-[2]-13-[1]-6-[1]-1

      [2]                                                  [1]
      5.7e-28                                              2.3e-15
      NQKSPLLKYRIECDCNETAELPNKSYDFVSGLWVDEGGEP             YCQTLITKTREGVDRSEHS
      ++++++++++  +++++++++++++++ ++++++ +++++             ++ ++ +++++++++++ +
1    MNQKSMLLEYKKTCQPASGTRTELYKYDLHMGLWKNENNEPLIKKFLNGGVTEVYGTTIETRTREGVDRSESSND

         [1]
         1.3e-14
         YCQTLITKTREGVDRSEHS
         + + +++++++++++++ +
76   ANVIILQSVVTYTRESIDRSETSK


448
  LENGTH = 64  COMBINED P-VALUE = 1.91e-25  E-VALUE =  2.3e-24
  DIAGRAM: [3]-32-[1]-2

     [3]                                        [1]
     1.7e-14                                    1.8e-17
     MKQKNPILYFR                                YCQTLITKTREGVDRSEHS
     +++++++++++                                + ++++++++++++ ++++
1    MKQTNPILYFREQSELKSSLNDEHTEMKKNEVASNNDSSFYKKISHTLITKTREAVDSSEHSDC


444
  LENGTH = 65  COMBINED P-VALUE = 6.40e-25  E-VALUE =  7.7e-24
  DIAGRAM: [3]-34-[1]-1

     [3]                                          [1]
     2.3e-11                                      3.1e-20
     MKQKNPILYFR                                  YCQTLITKTREGVDRSEHS
     ++ +++++ ++                                  +++++++++++++++++++
1    MEIKNPILKFRELTQFSEIAPSDEVFAPKLIIQSDFNSIKTDAVFVAQTLITKTREAVDASEHSY


445
  LENGTH = 62  COMBINED P-VALUE = 1.94e-23  E-VALUE =  2.3e-22
  DIAGRAM: [3]-31-[1]-1

     [3]                                       [1]
     3.7e-12                                   1.3e-18
     MKQKNPILYFR                               YCQTLITKTREGVDRSEHS
     ++++++++ ++                               ++++++++ ++++++++++
1    MKHTNPILLFREESCAERIPKTVTAATMAEGTDSTKLISVENYCQTLITRSREAADASEHSD


447
  LENGTH = 62  COMBINED P-VALUE = 1.26e-22  E-VALUE =  1.5e-21

        [3]                                     [1]
        4.1e-11                                 1.6e-18
        MKQKNPILYFR                             YCQTLITKTREGVDRSEHS
        +++++++++++                             ++++++++++++++ ++++
1    MELHKKLNPILHFRSIQKIQKPDRKDGDALTLANKDEDFKLRHKFQTLITETREAVDTSEHS


452
  LENGTH = 69  COMBINED P-VALUE = 4.40e-22  E-VALUE =  5.3e-21
  DIAGRAM: [3]-38-[1]-1

     [3]                                              [1]
     5.9e-10                                          2.0e-18
     MKQKNPILYFR                                      YCQTLITKTREGVDRSEHS
     +++++ ++ ++                                      ++ ++++++++++++++++
1    MAQKNLLLSFRKKIHHNQSLVKGNYNLAAGLWEQDSSFTIETLWNSDHMYGTTLITKTREGIDQSEGSN


446
  LENGTH = 65  COMBINED P-VALUE = 2.34e-21  E-VALUE =  2.8e-20
  DIAGRAM: [3]-34-[1]-1

     [3]                                          [1]
     3.0e-11                                      5.6e-17
     MKQKNPILYFR                                  YCQTLITKTREGVDRSEHS
     ++ +++++ ++                                   ++++++++++++++++++
1    METKNPILNFRRTSDSDVYTLKNEDPNNALPSKNNSTKTNAQVVINTPTLITRTREAADASEHSS


443
  LENGTH = 58  COMBINED P-VALUE = 5.37e-18  E-VALUE =  6.4e-17

        [3]                                 [1]
        9.8e-11                             3.8e-13
        MKQKNPILYFR                         YCQTLITKTREGVDRSEHS
         ++++++++++                         ++++ +++++++++ +  +
1    MYTNTQLNPILFFRFTLESKQREPNDAAFSTPDSELAVGQFQTRITETREAVDSSKNA


453
  LENGTH = 71  COMBINED P-VALUE = 1.62e-17  E-VALUE =  1.9e-16

                                                         [1]
                                                         7.8e-19
                                                         YCQTLITKTREGVDRSEHS
                                                         ++ ++++++++++++++++
1    MLQQSFLMNFKIKVNKTKKFTIPMNYNFLKGIWEIQKGSPFVNEMINSQHHDYGSTLVTETREGIDRSERS

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CPU: ip-172-31-7-169
Time 0.024 secs.

mast -oc . -nostatus meme.xml sequences.fa
