.table-humanization>:not(caption)>*>* {
    padding: .1rem .3rem;
    font-size: 90%;
}

.table-humanization-summary {
    font-size: 90%;
    padding: .1rem 1rem;
}

.table-humanness-summary {
    font-size: 85%;
    padding: .1rem 1rem;
}

.table-humanization-summary .btn {
    padding: 0 1rem;
}

.table-humanness-summary .btn {
    padding: 0 1rem;
    font-size: 85%;
}

.table-humanization-section td {
    border-top: 1px solid #dee2e6;
}

/* Mutation arrow between mutated residues in humanization table */
.mutation-arrow {
    position: relative;
}

.mutation-arrow:before {
    content: '→';
    font-weight: bold;
    display: inline-block;
    position: absolute;
    left: -0.45em;
    top: 1px;
}

/* Amino acid in center of peptide shown in larger font size */
.peptide-center {
    font-size: 125%;
    display: inline-block;
    position: relative;
    margin-top: -5px;
    top: 1px;
}

/* Highlight of CDR regions in humanization table */
.table-region-cdr1, .table-region-cdr2, .table-region-cdr3 {
    background-color: #eeeeee !important;
}

.loading-overlay {
    display: block;
    width: 100%;
    height: 100%;
    background: rgba(255, 255, 255, 0.5);
    position: absolute;
    z-index: 1000;
    top: 0;
    left: 0;
}

.designer-pills .nav-link {
    padding: .3rem 1rem;
}
.designer-pills.nav-pills .nav-link.active {
    background: #e9e9e9;
    color: black;
}

.designer-line a, .designer-line span {
    position: relative;
    display: inline-block;
    height: 21px;
    line-height: 20px;
    font-size: 13.5px;
    width: 8.4px;
    box-sizing: content-box;
    vertical-align: top;
    text-align: center;
    text-decoration: none;
    color: #000000;
    position: relative;
}

.designer-line a:not([href]) {
    cursor: default;
}


.designer-line a, .designer-line span {
    position: relative;
    display: inline-block;
    height: 21px;
    line-height: 20px;
    font-size: 13.5px;
    width: 8.5px;
    box-sizing: content-box;
    vertical-align: top;
    text-align: center;
    text-decoration: none;
    color: #000000;
    position: relative;
}

.designer-line a[href]:hover, .designer-line.designer-result-line span:hover, .designer-line .active {
    margin: -2px -2px;
    font-size: 16px;
    line-height: 24px;
    height: 25px;
    width: 12.4px;
    z-index: 100;
    text-decoration: none;
    box-shadow: 0px 0px 5px 5px white;
}

span[data-result-pos] {
    padding: 2px 0;
    cursor: pointer;
    position: relative;
}

.designer-parental-line a {
    color: #333333;
}

.designer-parental-line .designer-mut::after {
    content: '↓';
    color: #888888;
    font-size: 110%;
    z-index: 10;
    display: inline-block;
    position: absolute;
    bottom: -1.25rem;
    left: 0px;
}

.designer-parental-line .designer-mut-important::after {
    color: #000000;
    font-weight: bold;
}

.designer-parental-line .designer-mut:hover::after {
    left: 1.5px;
    z-index: 200;
}

.designer-result-line .designer-mut {
    font-weight: bold;
}
