Package: SPsimSeq
Title: Semi-parametric simulation tool for bulk and single-cell RNA
        sequencing data
Version: 1.0.0
Authors@R: 
    c(person(given = "Alemu Takele",
           family = "Assefa",
           role = c("aut"),
           email = "alemutak@hotmail.com"),
    person(given = "Olivier",
           family = "Thas",
           role = c("ths"),
           email = "Olivier.Thas@ugent.be"),
    person(given = "Joris",
           family = "Meys",
           role = c("cre"),
           email = "Joris.Meys@ugent.be"),
    person(given = "Stijn",
           family = "Hawinkel",
           role = c("aut"),
           email = "stijnhawinkel@hotmail.com"))
Description: SPsimSeq uses a specially designed exponential family for density estimation 
              to constructs the distribution of gene expression levels from a given real 
              RNA sequencing data (single-cell or bulk), and subsequently simulates a new 
              dataset from the estimated marginal distributions using Gaussian-copulas to 
              retain the dependence between genes. It allows simulation of multiple groups 
              and batches with any required sample size and library size.
License: GPL-2
Encoding: UTF-8
LazyData: true
URL: https://github.com/CenterForStatistics-UGent/SPsimSeq
Imports: stats, methods, SingleCellExperiment, fitdistrplus, graphics,
        edgeR, Hmisc, WGCNA, limma, mvtnorm, phyloseq, utils
biocViews: GeneExpression, RNASeq, SingleCell, Sequencing, DNASeq
RoxygenNote: 7.1.0
Suggests: knitr, rmarkdown, LSD, testthat, BiocStyle
VignetteBuilder: knitr
Depends: R (>= 4.0)
git_url: https://git.bioconductor.org/packages/SPsimSeq
git_branch: RELEASE_3_12
git_last_commit: 1123f18
git_last_commit_date: 2020-10-27
Date/Publication: 2020-10-27
NeedsCompilation: no
Packaged: 2020-10-28 03:48:21 UTC; biocbuild
Author: Alemu Takele Assefa [aut],
  Olivier Thas [ths],
  Joris Meys [cre],
  Stijn Hawinkel [aut]
Maintainer: Joris Meys <Joris.Meys@ugent.be>
Built: R 4.0.3; ; 2021-03-30 08:54:45 UTC; unix
