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<!DOCTYPE pathway SYSTEM "http://www.genome.jp/kegg/xml/KGML_v0.7.1_.dtd">
<!-- Creation date: Oct 1, 2012 11:48:21 +0900 (GMT+09:00) -->
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    <relation entry1="112" entry2="107" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="ubiquitination" value="+u"/>
    </relation>
    <relation entry1="30" entry2="112" type="PPrel">
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="1" entry2="36" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="25" entry2="49" type="PPrel">
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="25" entry2="33" type="PPrel">
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="79" entry2="76" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="76" entry2="27" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="28" entry2="29" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="113" entry2="5" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="42" entry2="114" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="108" entry2="95" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="108" entry2="94" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="100" entry2="94" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="102" entry2="94" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="102" entry2="92" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="95" entry2="115" type="PPrel">
        <subtype name="dissociation" value="-+-"/>
    </relation>
    <relation entry1="94" entry2="116" type="PPrel">
        <subtype name="dissociation" value="-+-"/>
    </relation>
    <relation entry1="116" entry2="72" type="GErel">
        <subtype name="expression" value="--&gt;"/>
    </relation>
    <relation entry1="99" entry2="88" type="GErel">
        <subtype name="repression" value="--|"/>
    </relation>
    <relation entry1="117" entry2="88" type="GErel">
        <subtype name="repression" value="--|"/>
    </relation>
    <relation entry1="88" entry2="89" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="89" entry2="51" type="GErel">
        <subtype name="expression" value="--&gt;"/>
    </relation>
    <relation entry1="99" entry2="34" type="GErel">
        <subtype name="expression" value="--&gt;"/>
    </relation>
    <relation entry1="52" entry2="54" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="90" entry2="94" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="93" entry2="94" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="82" entry2="108" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="80" entry2="108" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="81" entry2="108" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
</pathway>
