Package: multicrispr
Title: Multi-locus multi-purpose Crispr/Cas design
Version: 1.0.0
Encoding: UTF-8
Authors@R: c(person("Aditya",   "Bhagwat",    NULL, "aditya.bhagwat@mpi-bn.mpg.de",   c("aut", "cre")),
            person( "Johannes", "Graumann",   NULL, 'johannes.graumann@mpi-bn.mpg.de',c("sad", "ctb")),
            person( "Mette",    "Bentsen",    NULL, "mette.bentsen@mpi-bn.mpg.de",      "ctb"),
            person( "Jens",     "Preussner",  NULL, "jens.preussner@mpi-bn.mpg.de",     "ctb"),
            person( "Michael",  "Lawrence",   NULL, "lawrence.michael@gene.com",        "ctb"),
            person( "Hervé",    "Pagès",      NULL, "hpages.on.github@gmail.com",       "ctb"),
            person( "Mario",    "Looso",      NULL, "mario.looso@mpi-bn.mpg.de",      c("sad","rth")))
Description: This package is for designing Crispr/Cas9 and Prime Editing experiments.
             It contains functions to (1) define and transform genomic targets, (2) find spacers
             (4) count offtarget (mis)matches, and (5) compute Doench2016/2014 targeting efficiency. 
             Care has been taken for multicrispr to scale well towards large target sets, 
             enabling the design of large Crispr/Cas9 libraries.
License: GPL-2
LazyData: true
RoxygenNote: 7.1.1
Depends: R (>= 4.0)
Imports: assertive, BiocGenerics, Biostrings, BSgenome, CRISPRseek,
        data.table, GenomeInfoDb, GenomicFeatures, GenomicRanges,
        ggplot2, grid, karyoploteR, magrittr, methods, parallel,
        plyranges, Rbowtie, reticulate, rtracklayer, stats, stringi,
        tidyr, tidyselect, utils
Suggests: AnnotationHub, BiocStyle, BSgenome.Hsapiens.UCSC.hg38,
        BSgenome.Mmusculus.UCSC.mm10,
        BSgenome.Scerevisiae.UCSC.sacCer1, ensembldb, IRanges, knitr,
        magick, rmarkdown, testthat, TxDb.Mmusculus.UCSC.mm10.knownGene
VignetteBuilder: knitr
biocViews: CRISPR, Software
BugReports: https://gitlab.gwdg.de/loosolab/software/multicrispr/-/issues
URL: https://loosolab.pages.gwdg.de/software/multicrispr/
git_url: https://git.bioconductor.org/packages/multicrispr
git_branch: RELEASE_3_12
git_last_commit: c2d9878
git_last_commit_date: 2020-10-27
Date/Publication: 2020-10-27
NeedsCompilation: no
Packaged: 2020-10-28 01:51:49 UTC; biocbuild
Author: Aditya Bhagwat [aut, cre],
  Johannes Graumann [sad, ctb],
  Mette Bentsen [ctb],
  Jens Preussner [ctb],
  Michael Lawrence [ctb],
  Hervé Pagès [ctb],
  Mario Looso [sad, rth]
Maintainer: Aditya Bhagwat <aditya.bhagwat@mpi-bn.mpg.de>
Built: R 4.0.3; ; 2020-11-01 14:21:50 UTC; unix
