Package: gscreend
Type: Package
Title: Analysis of pooled genetic screens
Version: 1.2.0
Authors@R: c(
    person("Katharina", "Imkeller", email = "k.imkeller@dkfz.de", role = c("cre", "aut")),
    person("Wolfgang", "Huber", email = "wolfgang.huber@embl.de", role = "aut"))
Description: Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The analysis of such screens is based on the comparison of gRNA abundances before and after a cell proliferation phase. The gscreend packages takes gRNA counts as input and allows detection of genes whose knockout decreases or increases cell proliferation.
License: GPL-3
Encoding: UTF-8
LazyData: false
Depends: R (>= 3.6)
Imports: SummarizedExperiment, nloptr, fGarch, methods, BiocParallel,
        graphics
Suggests: knitr, testthat
VignetteBuilder: knitr
RoxygenNote: 6.1.1
biocViews: Software, StatisticalMethod, PooledScreens, CRISPR
URL: https://github.com/imkeller/gscreend
BugReports: https://github.com/imkeller/gscreend/issues
git_url: https://git.bioconductor.org/packages/gscreend
git_branch: RELEASE_3_11
git_last_commit: 63ed3c3
git_last_commit_date: 2020-04-27
Date/Publication: 2020-04-27
NeedsCompilation: no
Packaged: 2020-04-28 04:23:04 UTC; biocbuild
Author: Katharina Imkeller [cre, aut],
  Wolfgang Huber [aut]
Maintainer: Katharina Imkeller <k.imkeller@dkfz.de>
Built: R 4.0.0; ; 2020-05-14 12:10:04 UTC; unix
