Package: doubletrouble
Title: Identification and classification of duplicated genes
Version: 1.0.0
Date: 2022-05-29
Authors@R: 
    c(
    person(given = "Fabrício",
           family = "Almeida-Silva",
           role = c("aut", "cre"),
           email = "fabricio_almeidasilva@hotmail.com",
           comment = c(ORCID = "0000-0002-5314-2964")),
    person(given = "Yves",
           family = "Van de Peer",
           role = "aut",
           email = "yves.vandepeer@psb.vib-ugent.be",
           comment = c(ORCID = "0000-0003-4327-3730"))
    )
Description: doubletrouble aims to identify duplicated genes from
    whole-genome protein sequences and classify them based on their modes
    of duplication. The duplication modes are: 
    i. whole-genome duplication (WGD);
    ii. tandem duplication (TD);
    iii. proximal duplication (PD);
    iv. transposed duplication (TRD) and;
    v. dispersed duplication (DD).
    If users want a simpler classification scheme, duplicates can also be
    classified into WGD- and SSD-derived (small-scale duplication) gene pairs.
    Besides classifying gene pairs, users can also classify genes, so that
    each gene is assigned a unique mode of duplication. 
    Users can also calculate substitution rates per substitution site (i.e., Ka
    and Ks) from duplicate pairs, find peaks in Ks distributions with Gaussian
    Mixture Models (GMMs), and classify gene pairs into age groups based on Ks
    peaks.
License: GPL-3
URL: https://github.com/almeidasilvaf/doubletrouble
BugReports: https://support.bioconductor.org/t/doubletrouble
biocViews: Software, WholeGenome, ComparativeGenomics,
        FunctionalGenomics, Phylogenetics, Network
Encoding: UTF-8
LazyData: false
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports: syntenet, GenomicRanges, Biostrings, mclust, MSA2dist (>=
        1.1.5), ggplot2, stats, utils
Depends: R (>= 4.2.0)
Suggests: testthat (>= 3.0.0), knitr, feature, BiocStyle, rmarkdown,
        covr, sessioninfo
Config/testthat/edition: 3
VignetteBuilder: knitr
git_url: https://git.bioconductor.org/packages/doubletrouble
git_branch: RELEASE_3_17
git_last_commit: c7acec6
git_last_commit_date: 2023-04-25
Date/Publication: 2023-04-25
NeedsCompilation: no
Packaged: 2023-04-25 20:56:59 UTC; biocbuild
Author: Fabrício Almeida-Silva [aut, cre]
    (<https://orcid.org/0000-0002-5314-2964>),
  Yves Van de Peer [aut] (<https://orcid.org/0000-0003-4327-3730>)
Maintainer: Fabrício Almeida-Silva <fabricio_almeidasilva@hotmail.com>
Built: R 4.3.1; ; 2023-07-13 18:04:01 UTC; unix
