Package: biotmle
Title: Targeted Learning with Moderated Statistics for Biomarker
        Discovery
Version: 1.10.0
Authors@R: c(
    person("Nima", "Hejazi", email = "nh@nimahejazi.org",
           role = c("aut", "cre", "cph"),
           comment = c(ORCID = "0000-0002-7127-2789")),
    person("Alan", "Hubbard", email = "hubbard@berkeley.edu",
           role = c("aut", "ths"),
           comment = c(ORCID = "0000-0002-3769-0127")),
    person("Mark", "van der Laan", email = "laan@stat.berkeley.edu",
           role = c("aut", "ths"),
           comment = c(ORCID = "0000-0003-1432-5511")),
    person("Weixin", "Cai", email = "wcai@berkeley.edu",
           role = "ctb",
           comment = c(ORCID = "0000-0003-2680-3066"))
    )
Description: This package facilitates the discovery of biomarkers from
    biological sequencing data (e.g., microarrays, RNA-seq) based on the
    associations of potential biomarkers with exposure variables by implementing
    an inferential procedure that combines a generalization of moderated
    statistics with targeted minimum loss estimates of the average treatment
    effect whose estimator admits an asymptotically linear representations (in
    terms of an efficient influence function).
Depends: R (>= 3.4)
License: file LICENSE
URL: https://code.nimahejazi.org/biotmle
BugReports: https://github.com/nhejazi/biotmle/issues
Encoding: UTF-8
LazyData: true
Imports: stats, methods, dplyr, tibble, ggplot2, ggsci, superheat,
        assertthat, future, doFuture, tmle (>= 1.4.0.1), S4Vectors,
        BiocGenerics, BiocParallel, SummarizedExperiment, limma
Suggests: testthat, knitr, rmarkdown, BiocStyle, earth, glmnet,
        randomForest, SuperLearner, Matrix, DBI, biotmleData (>= 1.1.1)
VignetteBuilder: knitr
RoxygenNote: 6.1.1
biocViews: GeneExpression, DifferentialExpression, Sequencing,
        Microarray, RNASeq, ImmunoOncology
git_url: https://git.bioconductor.org/packages/biotmle
git_branch: RELEASE_3_10
git_last_commit: d9a0a1f
git_last_commit_date: 2019-10-29
Date/Publication: 2019-10-30
NeedsCompilation: no
Packaged: 2019-10-31 02:21:22 UTC; biocbuild
Author: Nima Hejazi [aut, cre, cph] (<https://orcid.org/0000-0002-7127-2789>),
  Alan Hubbard [aut, ths] (<https://orcid.org/0000-0002-3769-0127>),
  Mark van der Laan [aut, ths] (<https://orcid.org/0000-0003-1432-5511>),
  Weixin Cai [ctb] (<https://orcid.org/0000-0003-2680-3066>)
Maintainer: Nima Hejazi <nh@nimahejazi.org>
Built: R 3.6.1; ; 2019-11-03 01:10:57 UTC; unix
