SEQUENCEDIVERSITY(1)

statistics)"

NAME

sequenceDiversity

SYNOPSIS

sequenceDiversity –target 0,1,2,3,4,5,6,7 –file my.vcf

DESCRIPTION

The sequenceDiversity program calculates two popular metrics of haplotype diversity: pi and extended haplotype homozygoisty (eHH). Pi is calculated using the Nei and Li 1979 formulation. eHH a convenient way to think about haplotype diversity. When eHH = 0 all haplotypes in the window are unique and when eHH = 1 all haplotypes in the window are identical.

OPTIONS

    Output : 5 columns:
             1.  seqid
             2.  start of window
             3.  end of window
             4.  pi
             5.  eHH
    required: t,target     -- argument: a zero base comma separated list of target individuals corresponding to VCF columns
    required: f,file       -- argument: a properly formatted phased VCF file
    required: y,type       -- argument: type of genotype likelihood: PL, GL or GP
    optional: a,af         -- sites less than af  are filtered out; default is 0
    optional: r,region     -- argument: a tabix compliant region : "seqid:0-100" or "seqid"
    optional: w,window     -- argument: the number of SNPs per window; default is 20
    Type: statistics

EXIT VALUES

0   Success

not 0
    Failure

SEE ALSO

vcflib(1)

OTHER

LICENSE

Copyright 2011-2020 (C) Erik Garrison and vcflib contributors. MIT licensed.

AUTHORS
Erik Garrison and vcflib contributors.