= BioRuby 1.5.2 RELEASE NOTES

Few bug fixes have been made to the BioRuby 1.5.2 after the version 1.5.1 is
released.

* Fixed a parser bug in Bio::Fasta::Report, FASTA output (-m 10) parser,
  contributed by William Van Etten and Mark Wilkinson via GitHub.
* HTTPS is used to access GenomeNet BLAST web service, contributed
  by @ramadis via GitHub.
* Bio::Shell#seqstat: Fix format specifier syntax error.
* Bio::AAindex documentation fix, suggested by @kojix2 via GitHub.
* Suppress warning messages in Ruby 2.4 and later.


= BioRuby 1.5.1 RELEASE NOTES

Few changes have been made to the BioRuby 1.5.1 after the version 1.5.0 is
released.

== NEWS

=== HTTPS is used to access NCBI web services

As you may know, NCBI announced that all HTTP resources will be switched
to HTTPS on September 30, 2016. To follow the transition, all URLs for
accessing NCBI E-utilities in BioRuby are changed to use HTTPS.

In BioRuby, the following classes/modules are affected.

* Bio::NCBI::REST and descending classes
* Bio::PubMed

In some rare cases (especially when building Ruby and/or OpenSSL by yourself
from source code), Ruby does not include SSL/TLS support, or Ruby fails to
detect SSL root certificates. In such cases, you may need to reinstall or
upgrade Ruby, OpenSSL (or alternatives), and/or SSL root certificates with
appropriate configuration options. Alternatively, installing binary packages
is generally a good idea.


= BioRuby 1.5.0 RELEASE NOTES

A lot of changes have been made to the BioRuby 1.5.0 after the version 1.4.3
is released. This document describes important and/or incompatible changes
since the BioRuby 1.4.3 release.

For known problems, see KNOWN_ISSUES.rdoc.

== NEWS

=== Full support of Ruby 2.0.0, 2.1, and 2.2

Ruby 2.0.0, 2.1, and 2.2 are now recommended Ruby versions for running
BioRuby codes.

=== Support of Ruby 1.8 will be stopped

This release is the final BioRuby version that can be run on Ruby 1.8.

=== License is updated to the new Ruby's License

BioRuby is distributed under the same license as Ruby's. In October 2011,
Ruby's License was changed from a dual license with GPLv2 to a dual license
with 2-clause BSDL. Since BioRuby 1.5.0, we have updated to the
new version of Ruby's License. For details about the license, see COPYING
or COPYING.ja and BSDL. In addition, please do not forget to see LEGAL for
exception files that are subjected to different licenses.

=== Semantic Versioning will be introduced

We will adopt the Semantic Versioning since the next release version, which
will be BioRuby 1.5.1. This means that BioRuby 1.5.0 is NOT subject to the
Semantic Versioning.


== New features and improvements

=== New method Bio::FastaFormat#first_name

Bio::FastaFormat#first_name method is added to get the first word in the
definition line. This method was proposed by Ben J. Woodcroft.

=== Accuracy of Bio::SiRNA

Accuracy of siRNA designing algorithms in Bio::SiRNA is improved,
contributed by meso_cacase.

=== Speed up of Bio::ClustalW::Report

Running speed of Bio::ClustalW::Report is optimized, contributed by
Andrew Grimm.

=== Many warning messages are squashed

Most warning messages when running ruby with "-w" option, e.g. "assigned
but unused variable", "instance variable @xxx not initialized", are
suppressed. Fixes are contributed by Kenichi Kamiya, Andrew Grimm, and
BioRuby core members.

=== Refactoring of codes

Many existing codes are reviewed and refactored. Patches are contributed
by Iain Barnett, Kenichi Kamiya, and BioRuby core members.


== Bug fixes

=== Bugs due to remote server changes

==== Bio::PubMed

Bio::PubMed#search, query, and pmfetch are re-implemented by using NCBI
E-Utilities. They were broken because unofficial API was used.
Paul Leader reported the bug and gave discussion.

==== Bio::Hinv

Bio::Hinv did not work because of the API server URL is changed.

==== Bio::TogoWS::REST

* Bio::TogoWS::REST#search with offset and limit did not work due to
  TogoWS server spec change about URI escape.
* Bio::TogoWS::REST#convert did not work because of the spec change of
  TogoWS REST API.

=== Bio::Fetch

Bio::Fetch with default parameters did not work because BioRuby's default
BioFetch server had been down. We have decided not to restore the service.
For smooth migration of codes using BioRuby's BioFetch server, we provide
"bio-old-biofetch-emulator" gem. See below "Imcompatible changes" for details.

The bug was reported and discussed by Jose Irizarry, Robert A. Heiler, and
others.

=== BioSQL

* Only do gsub on bio_ref.reference.authors if it exists.
* Missing require when generating genbank output for BioSQL sequence.

Contributed by Brynjar Smari Bjarnason.

=== Bugs found in data format parsers

* Bio::PDB#seqres SEQRES serNum digits were extended in PDB v3.2 (2008).
  Thanks to a researcher who sent the patch.
* Bio::Blast::Default::Report parse error when subject sequence contains
  spaces. Edward Rice reported the bug.
* Bio::UniProtKB#gene_name raised NoMethodError when gene_names method
  returns nil. It should return nil. Candidate fix sent by Jose Irizarry.
* Bio::PhyloXML::Parser.open_uri did not return block return value when
  giving a block.

=== Other bugs

* lib/bio/shell/plugin/seq.rb: String#step and #skip (extended by bioruby
  shell) did not yield the last part of the string due to a change from
  Ruby 1.8 to 1.9.
* Documentation and typo fixes. Contributed by many persons, including
  Iain Barnett and ctSkennerton.


== Renamed features

=== Bio::SPTR, Bio::UniProt, Bio::SwissProt, and Bio::TrEMBL => Bio::UniProtKB

The classes for parsing UniProtKB (former SwissProt and TrEMBL) data,
Bio::SPTR, Bio::UniProt, Bio::SwissProt, and Bio::TrEMBL, are unified into
the new class name Bio::UniProtKB, and old names are deprecated.

For keeping backward compatibility, old class names Bio::SPTR, Bio::UniProt,
Bio::SwissProt, and Bio::TrEMBL are still available, but warning message
will be shown when using the old class names. These old class names will be
deleted in the future.

The file contatining Bio::UniProtKB class definition is also changed to
lib/bio/db/embl/uniprotkb.rb. For keeping backward compatibility, old
files sptr.rb, uniprot.rb, tremble.rb are still kept, but they will be
removed in the future.


== Deprecated features

=== Bio::RefSeq, Bio::DDBJ

Bio::RefSeq and Bio::DDBJ are deprecated because they are only an alias of
Bio::GenBank. Warning message will be shown when loading the classes and
initializing new instances. Please use Bio::GenBank instead.

lib/bio/db/genbank/ddbj.rb and lib/bio/db/genbank/refseq.rb which contain
Bio::DDBJ and Bio::RefSeq, respectively, are also deprecated. For keeping
backward compatibility, old file are still kept, but they will be removed
in the future.


== Removed features

=== Bio::SOAPWSDL

Bio::SOAPWSDL (lib/bio/io/soapwsdl.rb) is removed because SOAP4R
(SOAP/WSDL library in Ruby) is no longer bundled with Ruby since Ruby 1.9.
For Ruby 1.9 or later, some gems of SOAP4R are available, but we think they
are not well-maintained. Moreover, many SOAP servers have been retired
(see below). So, we give up maintaining Bio::SOAPWSDL and all SOAP client
classes in BioRuby.

=== Bio::EBI::SOAP

Bio::EBI::SOAP (lib/bio/io/ebisoap.rb) is removed because Bio::SOAPWSDL
is removed.

=== Bio::KEGG::API

Bio::KEGG::API is removed because KEGG API SOAP service was discontinued in
December 31, 2012. See http://www.kegg.jp/kegg/rest/ for the announcement
of service discontinuation.

=== Bio::DBGET

Bio::DBGET is removed because it only supports old original DBGET protocols
that was discontinued in 2004. Note that the DBGET is still available via
the web. See http://www.genome.jp/en/gn_dbget.html for details.

=== Bio::Ensembl

Bio::Ensembl is removed because it does not work after the renewal of Ensembl
web site in 2008. Instead, bio-ensembl gem which supports recent ensembl API
is available.

=== Bio::DDBJ::XML, Bio::DDBJ::REST

Bio::DDBJ::XML and Bio::DDBJ::REST are removed because DDBJ Web API (WABI)
web services were suspended in 2012 and then they were completely renewed
with incompatible APIs in 2013.

=== Bio::HGC::HiGet

Bio::HGC::HiGet (lib/bio/io/higet.rb) is removed because the HiGet web server
http://higet.hgc.jp/ have been down since 2011, and we think that the server
will not be restored again.

=== Bio::NCBI::SOAP

Bio::NCBI::SOAP is removed because it always raises error during the parsing
of WSDL files provided by NCBI. In addition, NCBI announced that the SOAP
web service for the E-utilities will be terminated on July 1, 2015. Instead,
Bio::NCBI::REST, REST client for the NCBI E-utility web service, is available.

=== Bio::KEGG::Taxonomy

Bio::KEGG::Taxonomy is removed because it does not work correctly. It raises
error, it falls into infinite loop, or it returns apparently broken data.
Moreover, KEGG closed public FTP site and the file "taxonomy" could only be
obtained by paid subscribers.

=== Bio.method_missing

Bio.method_missing, that aims to provide shortcuts of Bio::Shell methods
with shorter name without typing "Shell", is removed because most of the
methods raises error mainly due to bypassing of initialization procedure.
In addition, we now think that the use of method_missing should generally
be avoid unless it is really necessary.

=== extconf.rb

extconf.rb, an alternative way to install BioRuby to the system, is removed
because of avoiding potential confusions. Nowadays, extconf.rb is usually
only used for building native extensions, but no native extensions are
included in this release. Use gem or setup.rb to install BioRuby.


== Incompatible changes

Also see the above "Renamed features", "Deprecated features", and
"Removed features" sections.

=== Bio::Fetch

The BioRuby default BioFetch server http://bioruby.org/cgi-bin/biofetch.rb,
that was the default server for Bio::Fetch before BioRuby 1.4, is deprecated.
Due to the service stop, default server URL in Bio::Fetch is removed, and
we decide not to give any server URL by default for Bio::Fetch.

As an alternative, new class Bio::Fetch::EBI which uses the EBI Dbfetch
server is added. When changing codes form Bio::Fetch to Bio::Fetch::EBI,
be careful of the differences of database names, default and available
data formats between the former BioRuby BioFetch server and the EBI Dbfetch
server.

Methods directly affected are:

* Bio::Fetch.new (Bio::Fetch#initialize) does not have default server URL,
  and URL of a server must always be explicitly given as the first argument.
* Bio::Fetch.query is removed.

For the purpose running old codes, it is recommended to install
bio-old-biofetch-emulator gem. The bio-old-biofetch-emulator gem emulates
old BioRuby's default BioFetch server by using other existing web services.
See https://rubygems.org/gems/bio-old-biofetch-emulator for details.
We think many codes can run with no changes by simply installing the gem and
adding "-r bio-old-biofetch-emulator" into the command-line when executing
ruby.


== Known issues

The following issues are added or updated. See KNOWN_ISSUES.rdoc for other
already known issues.

=== Bio::PDB

Bio::PDB should be updated to follow PDB format version 3.3.

=== Bio::Blast::Report

NCBI announces that that they are makeing a new version of BLAST XML data
format. BioRuby should support it.

=== Bio::Blast::Default::Report

Bio::Blast::Default::Report currently supports legacy BLAST only.
It may be better to support BLAST+ text output format, although NCBI
do not recommend to do so because the format is unstable.

