>NZ_DS996811.1|c1|161472-162821|+|ZP_05086137.1|MATE_domain_family_protein
------------------------------------------------------------
----------------------------------------------------------ML
AMSGRTLMMIVDRLCLA---AYSEQT-L-TASGPAVFMGMSAISFFSGVTQIGRSVIAEA
YARS-GIEAAHKMGGR-LFAVAILCVLGLILTLPLLMNISQLSGR---PD--EVVALENV
YLSWAMLFGSIMILDS-AASCYFGAIGNTRLIFKASLAGQLVAMPMTYLLVFGAYGF-PE
LGMAGSAIGTVLGSLAVLIVYLRKTPR---A-LRVAAW------K-EARALLSKSRRA--
----LDVLALFKRGMPLGAHDSTDE---IGNTAIIWAVAIV-------GTTALAANNFNV
ILNYIGIVPVVGIANGATILSSQAIGRNQYDRIPKIISASLFVAFSYVAIVTVILQSFDR
EITSLFSLG--SYGQ-D----IFELSVS--VTSHIWYYAVAFAVSFIASGMLQSFHQNTF
VFKTRILTMWFGSVPA----SYLIAYNW-SIEEG--ALQLI----WISLST-FELALGL-
-LFTAKIFSCL----------------------------RDRNVPG--DLWETPIKRTEV
T-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_010627.1|c1|407423-408811|+|YP_001863604.1|multi_anti_extrusion_protein_MatE
------------------------------------------------------------
-------------------------------------MENKLLLTKIQRDFFFLS-EILI
GQLVVVAYSIADVIIIG---RTNPDL-L-GGLALGNAIYVPIIMTATAFYSAATIKAAKI
GAET-GVDSLRDIAYYGFASAIVVGTLVFCALKYFA-TIHHWSNQ---SP--YLVLAAQG
YLDTLALSALPSNLFR-VIAALANSIRATGYITALQAIGLIIKVALSLVLIDSSY---FR
FGLSGCGLSTAITFYVIFVGSLLLFLF-------NRNF--------FKF-HFDLFLLS--
-RKRLQLVALCKTGVPVALSTFAEF---ATFGYMTILIGRF-------GVQQLGAHQVVS
NLNVVAETVSSSLAVWISVKISNALVLEGRSMAVRKARSAILIAVAIGFLLTALQMFFGT
SLFRLY-----ADDQ-G----ILVISGK--ILPFESLLIFANCVLSGAAATLRARGINAF
PALMQVIGLWIGVAIL--GDGFAMQRLQ-LGDIDLAAGPGV----WCGVFL-GLLLSAL-
--MVTPIAIGD------------------------------GNAIR--RYIQWIRGSLAG
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_012731.1|c2|3394131-3395600|-|YP_002920241.1|putative_MATE_family_transport_protein
----------------------------------------------------MLFQHFSL
RSLLNV-----------------TSAVRQAVERTSWFKKRQRYRVLYWREISPLAVPILL
ENACVLLMGVLSTFLVS---WLGKEA-M-AGVGLADSFNMVIMSFFAAIDLGTTVVVAFS
LGKR-DRRRARAAARQSLAIMTLFSILLAGVIHAFGQEIIDFVAG---DATAQVKDLALT
YLELTALSYPAAAIAL-IGSGALRGAGTTKIPLLINGGMNILNILISSVLIYGIFSW-PG
LGFVGAGLGLTIARYIGAIATIWVLMV---G--LNPAL------R-LSL-KGYFKPFN--
-F--AIIWEVMGIGIPASIESVLFN---GGKLLTQMFVAGM-------GTNVIAGNFIAF
SVASLINLPGNALGSASTIITGKRLGKGQIGQAEFQAWHVFWLSTIILTLIAWGSAPFAG
FIASFY-----THEE-D----VKEVVKQ--LLWLNALFMPIWSLSWTLPCAFKGARDVRY
TMWVSMLGMWGCRVVA----GYTLGIVL-G-----MGVIGV----WLGMVL-DWAVRGV-
-LFYFRMVSGR----------------------------WLWKYPR--VKASSEES----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009792.1|c1|800808-802298|+|YP_001452424.1|hypothetical_protein
----------------------------------------------------MRFQLSSL
RSTLNV-----------------SAALRQAVSRTPWYAKRKSYKVLFWREITPLAVPIFL
ENTCVLLMGVLSTFLVS---WLGKEA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARAAARQSLVIMTLFAIVLAAVIHYFGEQIIDVVAG---EASSEVKALALT
YLELTVISYPAAAIAL-IGSGALRGAGNTKIPLLINGGMNILNIMISSVLIYGVFSW-QG
LGFVGAGLGLTISRYIGAVAIIWVLMI---G--FNPAL------R-ITL-KSYFKPLN--
-F--TIIWEVMGIGIPASIESVLFN---GGKLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGNALGSASTIITGRRLGNGQISQAEIQLRHVFWLSTIGLTAIAWLSAPFAG
LMASFY-----THDQ-D----VKDVVVV--LIWLNAAFMPIWSASWVLPSGFKGARDARF
AMWVSMLGMWGCRVVA----GYTLGIVL-G-----WGVVGV----WLGMFF-DWAVRAA-
-LFYWRMVSGR----------------------------WLWKYPR--PERIKSPVQPES
PTK---------------------------------------------------------
------------------------------------------------------------
---------
>NC_008563.1|c2|2130624-2132114|-|YP_853088.1|hypothetical_protein
------------------------------------------------------------
--------MWFHFLQLRSALKYLLCFTPGCSTALAGTLNARATKVLFWREITPLAVPIFM
ENACVLLMGVLSSFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDXKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---XGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIMLG------WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_011748.1|c2|2272868-2274508|-|YP_002403263.1|hypothetical_protein
-MRHILTAKNLLSNPIFNFPNCLPFLSTVCCICRQFVGENLCSFADSPSLFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIFM
ENACVLVMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTEVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIMLG------WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--PEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NZ_AAKB02000001.1|c2|4099413-4101053|+|ZP_03002641.1|MATE_efflux_family_protein
-MRHILTAKNLLSNPIFNFPNCLPFLSTVCCICRQFVGENLCSFADSPSLFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTEVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIMLG------WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--PEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_013361.1|c3|2792918-2794558|-|YP_003229849.1|hypothetical_protein
-MRHILTAKNLLSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSLFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTEVKALALT
YLELTVLSYPAVAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIMLG------WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--PEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>FN554766.1|c2|2313539-2315179|-|CBG35051.1|putative_membrane_protein
-MRHILTAKNLLSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSLFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTEVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--PEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_011742.1|c1|2038297-2039937|-|YP_002391758.1|hypothetical_protein
-MRHILTAKNLLSNPIFNFPNCLPFLSTVCCICRQFDGENLCSFADSPSLFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>AP009378.1|c2|1974472-1976112|+|BAI55387.1|conserved_hypothetical_protein
-MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVGTRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--PEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_011750.1|c2|1121386-1123026|+|YP_002407076.1|hypothetical_protein
-MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-AG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWCCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACGN01000094.1|c1|15934-17421|-|ZP_04003376.1|MATE_efflux_family_protein
----------------------------------------------------MWFHFLQL
RSALNI-----------------SSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>AM236324.1|c1|55149-56792|-|CAJ87602.1|hypothetical_protein
MLRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_004431.1|c2|2261008-2262648|+|NP_754340.1|hypothetical_protein
-MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLIDGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_007946.1|c2|2109870-2111507|-|YP_541200.1|hypothetical_protein
-MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNII-SGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>CP001969.1|c1|2190298-2191938|+|ADE88923.1|MATE_efflux_family_protein
-MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQL
RSALN-----------------ISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFM
ENACVLLMGVLSTFLVS---WLGKDA-M-AGVGLADSFNMVIMAFFAAIDLGTTVVVAFS
LGKR-DRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAG---DATTDVKALALT
YLELTVLSYPAAAITL-IGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW-PG
LGFVGAGLGLTISRYIGAVAILWVLAI---G--FNPAL------R-ISL-KSYFKPLN--
-F--SIIWEVMGIGIPASVESVLFT---SGRLLTQMFVAGM-------GTSVIAGNFIAF
SIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAG
VMASFY-----TQDP-Q----VKHVVVI--LIWLNALFMPIWSASWVLPAGFKGARDARY
AMWVSMLSMWGCRVVV----GYVLGIML-G-----WGVVGV----WMGMFA-DWAVRAV-
-LFYWRMVTGR----------------------------WLWKYPR--SEPQKCEKKPVV
SE----------------------------------------------------------
------------------------------------------------------------
---------
>NC_012880.1|c2|1786595-1788103|-|YP_002987126.1|hypothetical_protein
------------------------------------------------------MNGLNR
KKRVKVRSPPRFKSKTGNTILSTAKQLLSTLRDTSWYRKRRSNRVLLKREIMPLALPIFI
EGLCVVLMGIFSTFLVS---WLGKEA-M-AAVGLADSFNMLVIAFFTAVALGTAVVVAFN
LGQR-KRYMALQASRQSMSLLVLVSFVLVGVVELSGATIINLIAW---SAEPAVKTLALT
FLRLTVWGYPAIAIAL-VGCGALRGAGNTRLPMLINIAMNILNIIISGILIYGIGPW-HG
LGFIGAGLGITLSRYIGALFVILTLMK---G--FNGAL------R-ISF-KSYFYPFT--
-T--AILYEVLSIGIPASIESVMFN---IGKLITQRFVAGM-------GTEVIAGNFIAF
SIVALINLPGNSLGAASTIIVGTRLGKGQIAQSVRQLKHIFWLSNIGLCALGILSVPMAG
WLSSFY-----TNEP-D----VIKVAKE--LIWLNALFMPAWAASWVLPAGLKGAKDASY
TMWVALAGMWGCRVIA----GYILGVML-G-----FGVVGV----WMGMFF-DWIVRGI-
-LFYRRMASGK----------------------------WLWRYKK--EKTPNP------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_006155.1|c2|1907697-1909127|+|YP_070108.1|hypothetical_protein
------------------------------------------------------------
----------------MQMNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFI
EGLCVLLMGVFSTLLVS---WLGKEA-M-AAVGLADSFNMLIAAFFASVALGTSVVVAFS
LGQR-KRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMAN---QADPSVKAMALT
YLHFTVWNYPAMAITL-VGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNW-QG
LGFIGAGIGITLARSAGALVVVVLLIY---G--ANNTL------R-IPF-KAYFMPFT--
-S--AIMFEVLSIGIPASVESVMFN---IGKLITQRFVAGM-------GTDVIAGNFIAF
SIVAIINLPGNALGYTSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAG
FLASLY-----TDDP-A----VITVVKH--LIWMNALFMPIWAASWVLPAGLKGAKDASY
TMWVALAGMWGCRIIA----GYILGVTL-G-----FGVTGV----WMGMFL-DWMVRGV-
-LFYRRMSTGR----------------------------WLWRYR-----PSV-------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_010634.1|c1|1907687-1909111|+|YP_001872120.1|hypothetical_protein
------------------------------------------------------------
------------------MNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFI
EGLCVLLMGVFSTLLVS---WLGKEA-M-AAVGLADSFNMLIAAFFASVALGTSVVVAFS
LGQR-KRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMAN---QADPSVKAMALT
YLHFTVWNYPAMAITL-VGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNW-QG
LGFIGAGIGITLARSAGALVVVVLLIY---G--ANNTL------R-IPF-KAYFMPFT--
-S--AIMFEVLSIGIPASVESVMFN---IGKLITQRFVAGM-------GTDVIAGNFIAF
SIVAIINLPGNALGYTSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAG
FLASLY-----TDDP-A----VITVVKH--LIWMNALFMPIWAASWVLPAGLKGAKDASY
TMWVALAGMWGCRIIA----GYILGVTL-G-----FGVTGV----WMGMFL-DWMVRGV-
-LFYRRMSTGR----------------------------WLWRYRP--SV----------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_003155.4|c4|989357-990832|-|NP_822011.1|efflux_family_protein
----------------------------------------------------MGRARVAR
RRRWN--------------RNPLDSQGENHCGGSGGAERNVIVPPKVNLGVFSLSWPIFL
QLTFTYCMGLVDTWALG---RISDAA-A-ASVGSVNTVTTFVLMMFSFLGQGGSLVYARM
LGQG-KHRKVQECYSVALLLHILLGVVASAVLLIWAREMAQLLGL---RG--PLLSYGTT
FLQVVGGSCALHSLVA-MFGGVMAANGFTRAGMFAAVLTNIVNIVLIYLLVLLPAG--PR
WGVRGIALSTALATAAGLLFSAWLVFF---R--IRIRF------R-----RPPSAERL--
-R--EHGALLMAFALPTMLEPAFWQ---AAQITTTRIIAAV-------GPDELAARMYTL
SITNMIGMFGSALSQGLQIAVGHLAGAGELDRIRRITRTTRLVGVGVALTLALLAGLSGG
WIMDQF-----TDSP-E----VAESGRL--LLWCGLLYLPGSSLIMTTASTLRAVGHVTY
PAAVGILVLWGVFIPL----AYALSLPL-----G-LAIIGV----MIAMAI-DENLRAL-
-LLSIRWRHIS----------------------------APQRAHR--IVGKPKSAPVAG
S-----------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABYA01000596.1|c1|12897-14189|+|ZP_04690315.1|efflux_family_protein
------------------------------------------------------------
------------------------------------------------------------
-------MGLIDIWALG---MISDAA-A-GSVGSVNTVTTFVLMMFSFMGQGGSLVYARM
LGRG-EIKKVQECYFVALVLHVLLGVVVSAALFLWAEDVAGLLGL---EG--QHLAYGTS
FLRIVGGSCLIHSLGA-MLGGVMAANGRTRAAMFAAMFTNVVNIVLIGVLVLLPAG--PQ
WGVRGVALSTALATAAGLLFSAWLVFR-----------------R-IRIRFRRPADPR--
-QVKAHGALLVAFSLPTMLEPAFWQ---AAQIATTRIIAAV-------GEDELAARMYTL
SITNMIGMVSSALSQGLQIAVGHLVGAGDLDRIRRISRATRLGGIAAASVLALAAALSSH
WIMDGF-----TDSP-E----VAEAGRL--LLWCGLLYLPASSLIMTTASSLRAVGQVNY
PALTGILVLWGVFIPL----AYVLSLPL-----G-LAILGV----MIAMAV-DENLRAL-
-LLMVRWRYIS----------------------------APQRAGR--LVKEPKEAPSVS
V-----------------------------------------------------------
------------------------------------------------------------
---------
>NZ_DS999641.1|c12|7491615-7493045|+|ZP_06581116.1|efflux_family_protein
------------------------------------------------------------
---------------------MRFRDLRMPDSCHGGSERNISVPSKVNMGVLSLSWPIFF
QLAFTYCMGLIDIWALG---MISDAA-A-GSVGSVNTVTTFVLMMFSFMGQGGSLVYARM
LGRG-EIKKVQECYFVALVLHVLLGVVVSAALFLWAEDVAGLLGL---EG--QHLAYGTS
FLRIVGGSCLIHSLGA-MLGGVMAANGRTRAAMFAAMFTNVVNIVLIGVLVLLPAG--PQ
WGVRGVALSTALATAAGLLFSAWLVFR-------RIRI------------RFRRPADPRQ
VK--AHGALLVAFSLPTMLEPAFWQ---AAQIATTRIIAAV-------GEDELAARMYTL
SITNMIGMVSSALSQGLQIAVGHLVGAGDLDRIRRISRATRLGGIAAASVLALAAALSSH
WIMDGF-----TDSP-E----VAEAGRL--LLWCGLLYLPASSLIMTTASSLRAVGQVNY
PALTGILVLWGVFIPL----AYVLSLPL-----G-LAILGV----MIAMAV-DENLRAL-
-LLMVRWRYIS----------------------------APQRAGR--LVKEPKEAPSVS
V-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_011981.1|c1|290930-292306|+|YP_002539692.1|hypothetical_protein
------------------------------------------------------------
--------------------------MQTVETLGDAAPPRRPPSARTTKSLFRLSLPMFV
HSLLTFLVMLSEMLIMS---AYSANA-A-AAVAIVRQVLQVVFEISSMVGIGAVILISHS
LGRG-DEEGARQIATLAVFTNTLLGLLVGGLLFLGGPVALRILDV---PA--SIVHDASL
YLVLAAAAMVFNALAT-AAIACLRAFGSSRVIVMTGLFLSVIYIGATYVLVLGAGPI-PP
LGVTGAAYATLGSRIAMALMFGLAVYC-------ALGL------------RFASGPIR--
-ARLSLVRRMLVLAFPSVSDYIGYG---FYQLVLLGFVAGF-------GVSSVLSRTYVM
LAMTFLILVVMAVSQGNEVLVGYRWGEGRRQDAYRQALRSSFAATLVTTTIALLFWLMSD
QYLGLF-----GQGG-E----VLALSTY--LLLLTIFIQPGFAFNTVLLHSLRAVGDVRI
PVLVSIGLTWGLGLPL----AWLFCVQA-----D-YGVEGV----WYALII-EETLKAG-
-FMLSRWHGRG----------------------------WMGNAIA--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_003063.2|c2|716694-718055|-|NP_356947.2|siderophore_biosynthesis_protein
------------------------------------------------------------
------------------------------MEQGAATADKEDFNARGKPTLFQLSFPLLL
HSLLSFFVNLADTAIIS---AYSAEA-A-AAVAVAKQVMMIAFELSGLVGIGAVIVISRH
LGRG-EVEAARQVVAVALLTNTLVGLALGLSLMVAGPLVLEQLAG---ST--SLNDEAGL
YLNIVAVGMVFNGFIA-AGLACLRAFGHSRLILAFGVGVSAFYLLAEWVLILGVGPL-PG
MGVKGAALGTFSIRVMTTAILTPVLMW-------KLGL------R-FS---FSDTVAR--
-F--ATARRMIAIALPSVTDYIAYS---FYQIILLGLVARF-------GVEAVLGRTYTM
LAMAFLIVVVMAISQSNEVLIGYRFGERRLEAATSQALRSASLAAAATTSIATLIWLASV
PYIRLF-----TDNP-A----VIELCGS--LLFLTIFIQPGFAFNTILFQSLRAVGDVRW
PVFVSLTVTWGLGLST----AWFFCLFL-N-----LGVTGV----WLSLII-EETVKGS-
-LFLHRWLSRG------------------------------VRHEA--G-----------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACJY01000096.1|c1|30333-31673|+|ZP_06027250.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------------------MNSIGNVGKKTLISLTIPIFL
ELLLVTVVGNIDTIMLG---YYSDEA-V-GAIGGITQLLNIQNVIFSFINMATAILTAQF
LGAK-DYKRVKQVISVSLVLNVLLGLVLGGVYLFFWKSLLQKMNL---PE--ELVGIGKY
YFQMVGGLCVFQGIIL-SCGAILKSHGRATETLIINVGVNILNIIGNAFFIFGWLGI-PV
LGPTGVGISTVISRGIGCVVAFYMMCK---Y--CNFTF------R-----KKYIKPFP--
-F--KIVKNILSIGFPTAGEHLAWN---VGQLMVVAMVNTM-------GTTIITARTYLM
LISSFIMTLSIALGQGTAIQVGHLVGAGEIKEVYNKCLKSVKIAFIFAFVTTSVVCLLRK
PIMNIF-----TTNP-D----ILEASLK--IFPLIIILEMGRVFNIVIINSLHAAGDIKF
PMFIGISFVFTIAVLF----SYILGISL-----G-WGLAGI----WIANAM-DEWIRGL-
-AMYFRWKSKK----------------------------WLNKSFV--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_GG770381.1|c2|270127-271467|-|ZP_06747652.1|membrane_protein
------------------------------------------------------------
---------------------------------------MNNSSNVGRKTLFALTMPIFL
ELLLVTIVGNIDTIMLG---YYSDEA-V-GAIGGITQLLNIQNVIFSFINMATSILTAQF
LGAK-DYKRVKQVISVSLVLNILLGLILGGIYLFFWKSLLQRMNL---PT--ELVNIGKY
YFQMVGGLCIFQGIIL-SCGAILKSHGRPTETLIINVGVNILNIIGNAFFIFGWLGM-PV
LGPTGVGISTVISRGIGCVVAFYMMCK---Y--CNFTF------K-----KKYIKPFP--
-F--NIVKNILSIGLPTAGENLSWN---VGQLMIVAMVNTM-------GTTIITSRTYLM
LIASFIMTLSIALGQATAIQVGHLVGAGEVDKVYTKCLKSVKIAFIFAFLTTSIVCVFRK
PIMSIF-----TTNP-D----ILKASLK--IFPLMIILEMGRVFNIVIINSLHAAGDIKF
PMFMSISFVFLIAVLF----SYLFGISL-----G-WGLVGI----WIANAM-DEWIRGL-
-AMYFRWKSKK----------------------------WQNKSFV--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_008095.1|c5|3245211-3246623|-|YP_631006.1|MATE_efflux_family_protein
------------------------------------------------------------
--------------------------------MEVAASPNADPHGAPSLGLFRLTWPIFL
ELLLFMMMGTADTLMLS---GVSDDA-V-ASVGVVNQYVFICILIMEVVGHGAAIVVAQY
LGAR-RQTEAARISAIAVTLNLALGITVSAGLLLSGDAILGGMNL---QG--HMLAYAKT
YLHIVGGFLFIQALIN-VFAGLLRTYGFTRASMFVSLGMNVLHVGGNYVLIAGHFGF-PA
MGVAGAAISTVVSRAIALGVFVYVLYR---V--MPVKM------A-----PRDYVTFS--
-K--DYVRKILKVGLPSAFEQATYQ---GCQTVFLYYVTFL-------GAVALASRQYAH
AISQYVFLCSLAIGMGTSIIVGRLVGANRADDAYQQALRSLKWGLAITLVVDVAVVLLRV
PIVSLF-----TENA-D----IVRLTAQ--VIVIGLALETGRCFNLVLINALRAAGDATF
TVYMGIASMVCMSLPL----GYYLVFHM-----G-LGLAGV----WMAVAA-DEWVRGI-
-TMWLRWKSRA----------------------------WEKQVLV--SLDAETEAEAAP
VAAHA-------------------------------------------------------
------------------------------------------------------------
---------
>NZ_AAMD01000003.1|c1|105211-106512|+|ZP_01459507.1|efflux_protein
------------------------------------------------------------
------------------------------------------------------------
-----MLMGTADTLMLS---GVSDDS-V-AAVGVVNQFLFVCILIMEVVSNGASIVVAQY
LGAR-RTQEASRIAALSITLNFLLGGVVSAGLLGGGSAILERMNL---HG--QVLVHAQT
YMGITGGFIFLQALIN-VFSSLLRTYGFTKESMFVSLGMNILHVLGNYSLVFGHFGL-PR
MEVAGAAVSTVLSRCVALAVFIWMLYR---V--MEVRM------V-----FRDYVRFS--
-R--EYIQKILKVGVPSAIEQMMYH---CCQTVFLYYVTFL-------GPTALASRQYAM
AISQYVFLFSLAIGLGTSILIGRLVGANRPDDAYRRALESLKWSVAITVLVDVAAILFRK
PLIGFF-----TANN-E----ILQLTAQ--VMVLSLVLESGRSFNLVLVNALRAAGDAAF
TVYAGFGSMVCLSLPL----GYWLVFRM-N-----MGLAGI----WLAIAA-DEWVRGI-
-VMWLRWRSRA----------------------------WEKQALV--TQTEPAVGMALG
G-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_008268.1|c19|7144332-7145720|+|YP_706579.1|DNA-damage-inducible_protein_F_(_multi_anti
------------------------------------------------------------
-----------------------------------MADVSEVTGDATARTVFGLALPALG
VLAAEPIYLLFDIAVVG---RLGALA-L-AGLAVGGLILAQVSTQLTFLSYGTTARASRM
HGAG-DERGAVREGVQATWLALGIGALVIALVHLFARPVTSAIAG---GS--DIAAAAES
WLRIAVFGAPLILVAM-AGNGWMRGVQNTVRPLRFVIAGLVVSAVACPVLVHGLWGA-PR
LELEGSAVANVIGQALSASLFVGALVV-----------------------ERVPLRPR--
-W--SVMRAQMVLGRDLILRSLAFQ---ACFLSAAAVASRF-------GAAAVAAHQVVL
QLWNLVALTLDSLAIAAQALVGAALGAGHAKGATRLSWRITRWSTVFATGLALIFALGHG
VIPELF-----TSDQ-A----VLDEMAV--AWWFFVAIMPVAGVVFALDGVLLGAGDVAF
LRNATLSCALVGFLPL----IWLSMLHD-------WGLAGI----WTGLTV-FIILRML-
-AVVWRVGTGR----------------------------WAVVGAD--LQTRHGSDSDPA
AEHDRKGG----------------------------------------------------
------------------------------------------------------------
---------
>NZ_AAGP01000013.1|c1|48678-49994|+|ZP_05913596.1|multidrug_exporter_MOPMATE_family_membrane
------------------------------------------------------------
-------------------------------------------MAAIDKDILRLALPALG
ALIAEPIFLLSDTAMVG---HLGAGA-L-GSLAIASTILQTVLGLMIFLAYATTPRVARR
MGAG-DRSGAINAGFDGIWLALCTSVVLLAMGLPLLKPVIAAFEP---GA--EIAAGAHS
YLAISWWGLPFMLVVI-AATGLLRGLQDTRTPLIVAAAGCIANIGLNAIFIYGLD-----
MGVAGSALGTVIAQAGMCSVYVLISIR-------------------AAQRFHATFRPD--
-W--SGVLASAKTSGWLLVRNASLR---AALIILVFLATAM-------GTTELAAIQVAQ
SLFFALALALDSLAIAGQALIGLQLGARNSDAVAAINRRLCLWGIVFGVVVGLILLAGAG
LIPRGF-----SSDP-A----VVALLTS--LLPILALSMPIAGYVFVLDGVLMGAEDARY
LALAQLVAVGGYAILL----IPVVLYW--------PGALGL----WAAFCIGFVGLRAL-
-TLGWRVRNRS----------------------------WIARAVE--KGTS--------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_AADV02000001.1|c2|661222-662586|-|ZP_00514151.1|Multi_antimicrobial_extrusion_protein_MatE
------------------------------------------------------------
---------------------MESSFKRVHLETYKNRFLEFFNLPSFSWRFLRLASINIL
SNLMVPIAGLLSITFLG---HLKDIHHL-AGVTLATIIFNYLYRALGFLRTSTTGITAQG
MGRK-DSQEVLLVLLKNGLLALSLGLIILILQYPLRWIGFSLVSA---AP--LVKVSAQA
YYDTRIIGAPAVLLNF-VLIGWFLGKEQSGKVLWLSLIGNGANVILDYLLIIRWG-----
LESGGAGLATSLSQILMCLIGLLLVVK-------DINW---------QDVKQITKRIS--
-L--EQWKDNLMLNRDLFIRTLIFL---SAFSFFTNISSAM-------GTLTLAENSVLL
QIFSLVVYFIDGVAFATESLAGNFKGQGTKKQLIPLLKFSGILGFIFALGAVSIIILFPQ
TLFGLL-----TNHQ-E----IFPSLNA--HVIWLLPVLSFGSIAFILDGYFIGLAEGVM
LRNTALGATFVGFVPV-----ATIAWH--------YNNSNLL---WLALSL-FMVARVV-
-LLGLKVPKTL---------------------------------DN--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>EU140798.1|c1|12568-13965|-|ABX60156.1|multidrug_exporter_MatE
------------------------------------------------------------
------------------------------------MSLTFPSQYDFIPRYFRLAFTNVL
SNIIVPLSNLVSIMFLG---HLSEIHYL-AGVALAGNLLNFLYFVLSFLRMGTTALTAQA
VGRD-DREGVLLAGLLNGLIALVLGVAIILLQYPLGVLGFSILDV---GP--EVKSSAQA
YFNTQSWGAPAILLNF-VLLGWFLGREKNGLVVLLSVVGNAANIALDYLFIIHLD-----
WSSMGAGVASAASQYLTLLVGLFFVCK-------EIPW--------QEVKELAGKIWD--
-I--KAIRSTLTLNGNIFVSNLVCM---FTNLTFNYEGAQM-------GTIIYAQNALLL
QIWALSIYIVEGLGFCTETLAGNFKGKGATEQLAPLAKVSVGMALLVSLVFGGACWLFPD
DVFGLL-----TNHA-E----IIENIDI--FIPWLVLVLVCNSVCCILCGYFLGLAQGHT
LRNVNLIAFGVGFLPA----DVAAVKF--------ESNHIL----WLAFFL-FNAIGML-
-MFGAQLPRTF------------------------------ESVVE--NDSVSIPALEAS
RALTQMETLH--------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACYA01000027.1|c1|98447-99733|+|ZP_06307811.1|Multidrug_exporter_MatE_(CyrK)
------------------------------------------------------------
------------------------------------------------------------
-------------MFLG---HLSEIHYL-AGVALAGNLLNFLYFVLSFLRMGTTALTAQA
VGRD-DREGVLLAGLLNGLIALVLGVAIILLQYPLGVLGFSILDV---AP--EVKSSAQA
YFNTQSWGAPAILLNF-VLLGWFLGREKNGLVVLLSVVGNAANIALDYLFIIHLD-W---
-SSMGAGVASAASQYLTLLVGLFFVCK---E---IPWQ------E-VK--ELAGKIWD--
-I--KAIRSTLTLNGNIFVSNLVCM---FTNLTFNYEGAQM-------GTIIYAQNALLL
QIWALSIYIVEGLGFCTETLAGNFKGKGATEQLAPLAKVSVGMALLVSLVFGGACWLFPD
DVFGLL-----TNHA-E----IIENIDI--FIPWLVLVLVCNSVCCILCGYFLGLAQGHT
LRNVNLIAFGVGFLPA----DVAAVKF--------ESNHIL----WLAFFL-FNAIGML-
-MFGAQLPRTF------------------------------ESVVE--NDSVSIPALEAS
RALTQMETLH--------------------------------------------------
------------------------------------------------------------
---------
>NZ_DS999316.1|c1|695818-697116|-|ZP_05250100.1|predicted_protein
------------------------------------------------------------
----------------------------------------------MHKKIFLLSLPLIL
SNLVLPMVGIVNTALIG---HLSDSNYL-AAIGLGVSIINVICFMFSFFRMSLTGLIAQS
LN---NLEKMLEIVIKAVLIALLVSIIAFSFKSVILITVLKVVNI---SS--DIKILLAN
FYNIAIYILFFSLLNY-IFIGFFIGIGNPRVVLYSSIIYMSVAIVLSTIFVVILN-----
YNVVGVAISLVIASASCSIYLSIKTFR---YFYKSGSF--------SIKKLMDYRLLN--
-L--GSYMPFLQLNINIFVRSLCLL---LAFNSFYIFSSNY-------GKTILAANTILV
EIGMFFAMFLDALANTTESLVAQAYVDKNTSLLRETIYKTFVQSMILTLVLSLVYFSFSG
YIISIF-----TDIV-D----VKIQINK--YIIFSFLMPLFASFSFWIDGVFVGLLKT-V
AMRNAMILSAGVYIAS----VFLLQS---------YENYGL----WIALIL-FYIARTV-
-FLMPPLGQYI------------------------------KKGV---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_007954.1|c6|4219735-4221045|+|YP_564525.1|MATE_efflux_family_protein
------------------------------------------------------------
-----------------------------------------MLDLSRHKQLLALALPMIL
SNISTPLLGLVDTAVIG---HLSNAYFL-GGVALGGTIISLMVWLLGFLRMSTTGLVAQA
VGAN-DINSQYRLLMQGGILALLLGIGAMLIQAPLTELALELSQA---SA--EVSHYCQQ
YIAIRIYSIPFALLNL-VLLGWLLGRRSPMAAMWQLIIANAVNIILDIIFVVGLG-W---
-QVEGAAWASAIADIAAFTLACSLVYR---QLLKEPDF----------TPAKLWQGLN--
-L--SGLTPLLTLNRDIFIRSLCLQ---ACFSFVTFYGASQ-------GDIILAANAVLM
NLLMLISYALDGIAYYAEAEVGKAYGEKDKLKLKQGVSLAFYWSLAIGLAFSIIFWLFGG
HIISLL-----TDIS-Q----VKTTAEQ--YLPWLIALPLLSFACYLFDGVYIGAAKGKV
MRNSMILASFGVFFPL-----WFITQS--------LGNHGL----WLAFSA-FMLARSL-
-LLGLDYRFSK----------------------------DF-------------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_013410.1|c1|2991845-2993260|+|YP_003250491.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MVDAILNRFYKPSKFKKNGDVKDVLVVALPMLL
SMSFDTFMTFIDRLFLS---KLGPAE-MNAALG-AGAVQLALTMFFTGAISYTTAMVAQR
LGGK-KRWDCARVFMQSVYLS-LISVPLLYLTIPLGHFAFGLEHL---PA--DQLEYQKT
YFNILMFGGVINLLRN-AAPCFFSGIGETKVVMKAAFAGMIVNVACNFVLIYGYGPI-PA
MGVAGAAYGTLIGNVVSTVILFAKFFS-------NSCH--------RRFRTRFAFAFS--
-W--PLTRELLKKGIPSGVEMFLNM---AAFQSLILMFHAL-------GPEAATASSIMF
NWDLVAYVPLMGLEVASTSLVGRYVGAKNAAAATRSTYSGLKLGWGYSLVMGIFFIFLPG
VLTDIFKPDVAEATESALAIFNAARPMSMFMLRIATFYIFVEVLLVIYAGALRGAGDTVW
VMFACGIMNWFVAIAL-----YIVAYVF-H-----LPAHYA----WIVVVA-VYSTAPL-
-IFWRRWKSGK------------------------------WRRHV--MNAK--------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_005027.1|c2|1114250-1115653|+|NP_864748.1|multidrug_resistance_protein_norM
------------------------------------------------------------
---------------------------MISAL----------------KEVLRVAVPLMV
STGMFSLVLFVDRTLLL---WHEPSQ-M-GAAMAAGNLFWVSVCVFVGIASMTSAIISQY
IGAD-QPKRVGQLLWQA-TWFSAATLPWFVLVGSFGESLFRLTDQ---PE--HLIPMQAA
YFRILMWGGAGEVLQT-ALSGFYSGTHRTRTIMLVSLASGVLNLLLDLVLIFGVGSADPE
TGLRFLELG-IAGAAIASTLSF--WFK---A-VCYAVLLMKPIER-ERYGILRGIRLN--
-R--RMMKRLIYFGLPAGLMYVTEA---GGFTVIVLQIGRL-------GDVPLQATTMAI
NFNMIAFIPLVGMSIAASVLVGQHLIRTGPGPAIRCVIAALVVGWAYSLAWAIAYVFAPG
GLIALYSLSPTGVDSEV----AFEIAEK--LLGFVAIYVILDATQLILAGALRGAGDTWF
VLLAGLFVSAVAVVVG----TVWQPVAA-RFQDPDGQAAALVALDWWWWVITGWVCTLA-
IVMAGRFLQGK------------------------------WQRMR--MV----------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_GG657999.1|c1|37176-38588|-|ZP_04571952.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------MEIMISLIQFFSSSVLLKQEKTEQEIPDKKTINKEYWKVAFPAAI
EGVLLNLMLLADLIMVG---MLGIEK-A-AAVGIVSQPKMILQMIVSAAGVAITAIVARR
KGEG-DEEGLNSCIKQSLLLLGLLYFLFVCLSFIFSKNIVSFAGA---NE--DYIEYASI
YFQYIALSVFFKALCV-VLSSAQIGVGNTKIVLISGMIGNALNVLLNYLLIFGKYGF-PE
MGIQGAAIATVIGNAVIFVILLYSVTK--------GDY------G-INILKKGSYHFT--
-K--KVLAPLQEIGTNSFLEHIFER---IGLFIFARMIASL-------GTVAMGTHHYCI
LLWDLYYYFGVGMSSASASFTGRKLGEKRKDLAILYMRAAQYSGLWISIFVGIIFYLLRN
SIFSLM-----ISDE-R----VILLGSS--VMMIISLLIIPQTQAQVTAGVLRGAGDNRF
IAIYSLFISAILRPCL----AYIFAFIW-K-----LGLVGI----WIAFFS-DEFLKML-
-LAQYRIQKGI----------------------------WLQKKI---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_GG770341.1|c3|1405335-1406738|+|ZP_06751205.1|MATE_efflux_family_protein
------------------------------------------------------------
------------------MISLIQFFSSSVLLKQEKTEQEIPDKKTINKEYWKVAFPAAI
EGVLLNLMLLADLIMVG---MLGIEK-A-AAVGIVSQPKMILQMIVSAAGVAITAIVARR
KGEG-DEEGLNSCIKQSLLLLGLLYFLFVCLSFIFSKNIVSFAGA---NE--DYIEYASI
YFQYIALSVFFKALCV-ILSSAQIGVGNTKIVLISGMIGNALNVLLNYLLIFGKYGF-PE
MGIQGAAIATVIGNAVIFVILLYSVTK---G-----DY------G-INILKKGSYHFT--
-K--KVLAPLQEIGTNSFLEHIFER---IGLFIFARMIASL-------GTVAMGTHHYCI
LLWDLYYYFGVGMSSASASFTGRKLGEKRKDLAILYMRAAQYSGLWISIFVGIIFYLLKN
SIFSLM-----ISDE-R----VILLGS--SVMMIISLLIIPQTQAQVTAGVLRGAGDNRF
IAIYSLFISAILRPCL----AYIFAFIW-----K-LGLVGI----WIAFFS-DEFLKML-
-LAQYRIQKGI----------------------------WLQKRI---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_008027.1|c3|2238439-2239821|-|YP_607773.1|multidrug_efflux_protein_MATE_family
------------------------------------------------------------
--------------------------------------MTDTTLGTWCREIIKLATPILG
VRVLHIAVNVIGMLLIA---RLGPSE-V-AAGALVTVLCTSIQVIALSPLLATGICIARR
LGQG-QATGVGVDLRQGLFMSVAIGVL-AALALLALPTLMPLLGE---PE--ALQALTAD
YWRAMAWGMPPFLCTA-CCHQLFFPAGKGRLVMVFSAINLAGVLLLGTALLHGAWGL-PA
LGMAGWAHAVSTMNWVVLLLTLGYLAL-------APAM------------RPYQLFTREQ
LWAPDRLKAFFVLGVPITVQFASEL---LAFSLVNIMVGWL-------GVGALSVQQIVI
QCATVALMIPMGAGQACTLLISRAMGRGDGQAVRRIGLAATVLVGAVMAALALVYLLLPR
PIIDAYLDPARADYP-T----LAALATG--MLAVVAFSQALDALRNLMLSALRGLPDIWG
PMWLNMALLWVLGMPL----CYLLAFPG-G-----LGLWGI----NGGLLL-AFGLGAV-
-LMLGRFHQRT------------------------------APLSA--VPARQPVHE---
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_008392.1|c2|463603-464973|-|YP_777812.1|MATE_efflux_family_protein
------------------------------------------------------------
--------------------------------MNGFVEKTATLPPSSTREALKISLPIMI
SQFVVMIGGFVSNLLLS---RVDATT-F-AAGLLINAVQMLLMTVVFGMLFALSPLIGHV
KGEGREPERIGHLFSAALAVAMLLCVP-TIVVLLFIGPILTALHQ---PP--ELVGACTG
FFRIYVYSLPAVGIIS-VCVQLLLGILKQALVLLYSLCSLLLTTLLGYLLIFGKFGF-PM
LGLEGLAWAQSITAWAAALVLGGFVLS-------HGSH------RPYGLLAMHGQAVK--
----QGVTRIVKVGLPISVQMGNEI---LSFFVTTVMVGWL-------GIAALNVQQVAT
RYLLLLVIPIVGLSQAATVVASRHFGGGRLGAVKEVGDAYTRMGVIYSLIVLAAFALVPS
LFVRVF-----VADT-PENAGIYHTLSI--ILVLIAVGQIFDAARNTLTGALRGLQDTKF
PMKVSMILIWPVGVPL----AYVMGFTL-G-----WGLVGI----TVAHDL-VMAVGAL-
-ILWQRWRNRF------------------------------PRQA---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABBE01000764.1|c1|11549-12874|-|ZP_02381202.1|MATE_efflux_family_protein
------------------------------------------------------------
-----------------------------------------------MREALKISLPIMI
SQFVVMIGGFVSNLLLS---RVDAAT-F-AAGLLINSVQMLLMTVVFGMLFALSPLIGHV
KGEGREPERIGHLFSAALVVAMLL-CVPTIIVLLFMGPILTALHQ---PP--ELVSACTG
FFRIYVYSLPAVGIIS-VCVQLLLGILKQALVLLYSLCSLLLTTLLGYLLIFGKLGL-PA
LGLDGLAWAQSITAWVAALVLGGFVLS---H---GSHR------P-YGLLAMHGEPVR--
----QGVTRIVKVGFPISVQMGNEI---LSFFVTTVMVGWL-------GIAALNVQQVAT
RYLLLLVIPIVGLSQAATVVSSRHFGGGRLGAVKQVGDAYTRMGVVYSLIVLAAFALMPS
LFVRVF-----VADT-PENAGIYHTLSV--ILVLIAIGQIFDAARNTLTGALRGLQDTQF
PMKVSMILIWPVGVPL----AYVMGFTL-D-----WGLVGI----TVAHDI-VMVIGAA-
-ILWQRWRNRF------------------------------PRHG---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_005966.1|c2|2699483-2700823|-|YP_047327.1|putative_multidrug_resistance_pump
------------------------------------------------------------
----------------------------------------MNILKDILFPILKLALPLIL
IQICQASLGVINTMVAGRYYYID----L-AGIGLGSNMWTPVFILFTGILYVLVPKISAM
QQH--SSQEIGVLIQQGKRVAFLLSIFGFILIQLLAFLCPWLIG----DQ--QVAQIAKQ
YLHFVAFGVPGLVYMT-LFRFVSEGHSLLKPIILTYAILLVCDASLCLVLVNGIGFI-PE
MGGAGTGLATAMSAYIACFCMYQFVSK---A---IPEL------------KIKRIQVG--
-F--KESLGLLKQGLPIGITLILQI---LALATLAFFASQL-------GAKAIAAHQIVI
NIAMLIIMIPIAISSATTIRIAYFSATNHHQGKISTSLCVVVLTLIYSFLMAGILIGFAQ
HIVSLF-----TQDA-E----VLNVAVG--LMSYVAIFLIFDAIQTVASGVLRGLHQFMQ
PLFIILFCYWFVIIPL----SYLMGVQG-WLQVR-ANVDVI----WIVLTC-GISLAAV-
-LLTIQSYCHV------------------------------TGIMN--KRS---------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACYR01000092.1|c1|48233-49588|-|ZP_06783600.1|putative_multidrug_resistance_pump
------------------------------------------------------------
----------------------------------------MNMLKDISLPILKLALPLIL
IQICQASLGVINTIVAG---RYHYID-L-AGIGLGSNMWTPVFILFTGVLYVLVPKISAV
QQA--HKAEIATLIQQGKKMAFLLSIFGFILIQLLALLCPWLIEN---P---QVASIAKQ
YLHFVAFGVPGLVYMT-LFRFISEGHSLLKPIILTYLILLFCDALLCVVLVKGIGFI-SE
IGGAGTGLATAISAYIACFCMYQLVAK---A---VPEL------------KTNKAKVN--
-I--QQSLQLLKQGLPIGITLVLQI---LALATLAFFASQL-------GAKAIAAHQIVI
NIAMLIIMIPIAISSATTIRVAYFSATHDHQSKLATSAAVAVITLIYGVVIAGLLVAFAE
PLTGLF-----SNDA-E----VLNIAAG--LMSFIAVFLIFDAIQTVASGVLRGLQQFMQ
PLFVILFCYWLVIIPL----SYLMGVRG-WLQER-ANVDVI----WLVLTC-GISLAAI-
-LLVIQSYRYL------------------------------KKGEL--PVGETIST----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009085.1|c3|2960436-2961692|-|YP_001085581.1|putative_multidrug_resistance_pump
------------------------------------------------------------
------------------------------------------------------------
--MVAGRYHYID---------------L-AGIGLGSNMWTPVFILFTGILYVLVPKISAM
QQA--NKAEIATLIQQGKKVAFLLSIFGFILIQLLALLCPWLIEN---P---QVASIAKQ
YLHFVAFGVPGLVYMT-LFRFISEGHSLLKPIILTYLILLFCDALLCVVLVKGIGFI-SE
IGGAGTGLATAISAYIACFCMYQLVAK---A---VPEL------------KTNKAKVN--
-I--QQSLQLLKQGLPIGITLVLQI---LALATLAFFASQL-------GAKAIAAHQIVI
NIAMLIIMIPIAISSATTIRVAYFSATHDHQSKLATSAAVAVITLIYGVVIAGLLVAFAE
PLTGLF-----SNDA-E----VLNIAAG--LMSFIAVFLIFDAIQTVASGVLRGLQQFMQ
PLFVILFCYWLVIIPL----SYLMGVRG-WLQER-ANVDVI----WLVLTC-GISLAAI-
-LLVIQSYRYL------------------------------KKGEL--PVGETIST----
------------------------------------------------------------
------------------------------------------------------------
---------
>GQ979609.2|c1|48491-49915|-|ADA69242.1|MatE_efflux_transporter
------------------------------------------------------------
-------------------------------MEQITSTEFKSDFLTEARVSLGLAVPLAV
AQLAEFTIPVINSVMMG---LLGTQN-L-AAGALGVVIFLTLASICIGILRAAGALAAEA
FGAN-NLDRVSRINCQGLWLAVALSLPAMLLLWNC-DSILPLLGQ---EE--SNILLTKS
YLHVVVWGLPAMLGFL-YLKQIAAAINFPQFGMVIIVVSLLLNIPVNYVLMFGFLGF-PA
LGLAGISWGTMLVYWVSFLASVMLIYF-------HPNS------R-DYKLFRYLDEFD--
-R--EIFGKIFQIGWPTGIQLAIEM---GLFTITAMLMGRL-------GTSSLAAHEIAL
QASSIFSAITMAISYAVTARVGQMMGEKNPKGVIRATFVNLSLSVLLAFVVAIGFELFSQ
PIATLYLDINNPDNA-V----AITQAIN--FLKLVAVYQVFSSIQGIAVGALLGLQDTRV
PMIINTLSFWGVGLGG----GYLMGIIL-G-----WGGTGL----WYGLIM-APAISSL-
-ILVGRFYLRA------------------------------KKFEG--DLTGVPDQTPVS
TLST--------------------------------------------------------
------------------------------------------------------------
---------
>NC_005126.1|c11|4111479-4112840|-|NP_930733.1|hypothetical_protein
------------------------------------------------------------
--------------------------------------MAKFSNWRELKQLLFFSFPIIV
SQIARTAMSFVDIVMSG---HYATAD-L-AAVTLGSSIWFPIFVLGYGTIIMLAADVAKQ
KAQH-DDEGIKDSLKNYLFLAVILSIPIIILLML-VSWLLSFIGI---DE--HILEITQG
YVIALACGVPSVMIFN-VFRSFLQGLEDTKIAMYLSAGALLLNIPLNYILIYGKLGL-PE
MGGIGAGITTAIINNLIAVCLIIYFLL-------KKEY------------RRYRPDFSLP
KY--NSLIRTFYIGMPSGLALFVEM---VFLDVIAITAAPL-------GAQVIAAHNIML
NITSIIYTITGGIAAAVTVRVGSYIGKRDKISLTGTIKISIALILSISAVIGVLIYYFAG
SFISLY-----TNDN-G----VIIIALN--IIFLLCLFQFFDSCQAALSGILRGFHDTRS
VFYAPLFGYWLVGLPL----GFILALTD-WVTER-MGIIGF----WYGLVL-GLFVNAI-
-LLFIILKVRQ------------------------------RGMIS--RLISY-------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_011567.1|c2|1399593-1400933|-|YP_002315741.1|multidrug_efflux_protein
------------------------------------------------------------
-------------------------------------MKETYTLKEKIKQFLHILFPVFL
TQISLYMMNFFDVTMTG---KYSSVD-L-AGVAIGSNIWIAIFTGIGGVLTGLTPIVSQA
FGAK-DHERISRTVEQAIYLAIIFACFVLTIIYFLVPILLENMYI---ES--NVQIVAYQ
YLQALCIGIVPIFIYY-VLRSFMDALGQTKVTMTLTLCSLPLNVLLNDIFIFGRWGV-PA
FGGVGAGYATSITYCCLLLCAFLLIRF-------RKPF------S-TYNILKKLHPIS--
-L--SIWKQLILIGIPIGLAIFFET---SIFSAVTLLMSQF-------GTTAIAAHQAAL
NFGSLLYMIPLSVSLTLTIIVGFEVGASRLEHAKRYCIIGISSAVMMAIVASIVLLLFRE
PIAFLY-----TNDE-H----VLQWTKQ--FLLYVLFFQFSDAIAAPIQGALRGYKDVRF
PFFIALVSYWFVGLPV----GYIFAHYT-T-----AGPFGY----WIGLIT-GLASGAI-
-LLFVRLRQK-------------------------------WKHI---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_012880.1|c3|2000493-2001866|-|YP_002987299.1|multidrug_efflux_protein
------------------------------------------------------------
----------------------------------------MQKYLSEARQLLSLAIPVII
AQVSQTAMGVVDTIMAG---SYSATD-M-AAVAVGTSIWLPAILFGHGLLMALTPVVAHL
NGSG-RRDRIAHQTRQAFLLAAAISVVTMFALAQGKHAIHLMNNG---SP--ELAEKAIG
YLHALLWGVPGYLFYQ-VLRSQCEGLSKTKPGMVIGFIGLLINIPINYVFIHGKLGM-PE
LGGIGCGVATATVYWVMLLLLAGYLQR---SYWQRDIR------Q-----RKTTWRPD--
-W--STLKRLFNLGLPIALAMLFEV---TLFAIVALLVLPL-------GVVEVAGHQIAL
NFSSLMFVLPLSLGVAATIRIGHRLGQGSVDAARIAAHTSILSGVALAICTAIFTITLRK
PIALLY-----NQNP-D----VVAMASH--LMLLAAVYQISDAVQVIGSGVLRGYKDTRA
IFFITFIAYWVLGLPS----GYILALTD-WLVPR-MGPAGF----WCGFII-GLTSSAI-
-MMVSRIR-------------------------------WVQRQPA--ELTLTRAAR---
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABLK01000076.1|c1|20435-21841|+|ZP_02907416.1|MATE_efflux_family_protein
------------------------------------------------------------
----------------------------------------MPTLGTHARDLTAIAVPIAL
SLVAQKVVNVTDAVMLG---GLGPHA-L-AAGALATTVFFTIMTLMHGLMSGLTVLLAHA
RGAG-KDAEVPTLYGSALLVAALLSIPLFIAMSHL-ETILLAAGT---EP--ELARNAGR
SAAVLRWGAPGALLGLSLMRAFLPAVGGARVLLSVSCAVMLVNAVLNHAFIYGFG-WLPA
MGYVGSAAATATTLTISAVCLLWAAHR-------GPRY----------RVFTQGLRVD--
-R--AAMRQMLVIGAPVSVSLGVEA---AVFLVAGLSLSSF-------DPAALPAHQIAF
SIVDTIFAVPLALASAANVRLGYWSGARRPAEVTTAGALALSMGAAFMLGTSTLLWLLPH
TLVSFYLDTSLLTNR-E----TVMGAVT--LLGVAAFFQLGDGLQSIAAGCLRGLKDTKI
PMLLSAFGYWGVAFPL----GQWLARSR-H-----MGATGI----WIGLAT-GLTAVAL-
-LLTIRFFALS------------------------------RRQGR--PPMRSQPSRTRD
HHPFRRNDP---------------------------------------------------
------------------------------------------------------------
---------
>NC_008027.1|c5|2639312-2640739|-|YP_608120.1|multidrug_efflux_protein_NorA
------------------------------------------------------------
---------------------------------MLEHKSTTRRPTGELMILLAMAGPLMA
AQLSKVVMVFTDTYMMG---RLGAEA-L-AGGGVGASIYSFLTFSFSGVISGIGTLIAIA
HGSR-DITSVRRSCQSGLLIALLLAALGMLVLWL-AAPLLRSLGQ---PP--QSIDAFIA
FTHAVAFALPGYLVFM-ALRNFVSALGDTKPVMVISMAGAVLNLALNLVIINQWFGI-PF
LGLRGIGAVTASVSLLMAVSLAGYIAL-------TPRY------H-PYRIFEGFLDID--
-W--GILRQALRFGIPVGLSFAIEL---SLFTCAALMMGHF-------GVVVQAAHHVAM
QAVLIAFVVPISLSSATSYRVGQLVGAGRVAETKRVARIGLACGAVASLIFAPLFLVFPT
EIASLF-VHAGTADSLL----LKSTVAS--LLAVAVWFLLFDGAQNILLGALRGLKALKT
SLALVAIFYWVIALPT----AYILGIHLE------LGPRYI----WAGLAI-GLAAATF-
-AMYLGLELIV------------------------------NRQTR--EARAQMPGTAVL
AQEAKGS-----------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABBM01000615.1|c1|17675-19051|-|ZP_02465535.1|efflux_protein
------------------------------------------------------------
-------------------------------------MKPHGQFWLDARHIGALAAPLIL
TQLAQVALTTTDIVMMG---MLGPRE-I-AAGGLALTLFNQLRTMGTGLVTGTGNLVAFA
NGQD-DAARIMRLVRASFALSTLAALAFVLLMLA-VERPLVWLGQ---NP--GVARQTAL
YLAAAAPGMLPCLWFQ-SLRQYTVGLRKPGPLLAITVVSIAVNAVLDYALMFGRLGF-PE
LGLTGVACATSVVYLLSFVAFLTIAKR-------RAAL--------REHLSLAFWRAD--
-A--DAFRQTLKMGVPIAATYGSEA---AFFTVLTLVIGTL-------GTDALAAQTVVN
QVIYIVFMISVGLSHASSISISHACAQHDYRGARRLGYTGLALGVGAMLIVALPYLVAPT
SVLAPFLARGSAANA-D----VLRLAAG--LLTIAALLQIFDCSQNIGVGILRGLGDVTS
SFRISIVGYWMIGLPV----AWAAGVML-G-----YGIYGI----WIGLAI-GLAATSS-
-MLLRKFEYRL------------------------------DALAK--QAGAARS-----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_013410.1|c1|3012108-3013838|+|YP_003250504.1|multi_antimicrobial_extrusion_protein_MatE
------------------------------------------------------------
-----------------------------------------MFKTFLSRKFFSLLLSSTI
GQLVITVLTLSDSMIAG--VMLGEDA-V-AAICLVVPAYSLAGFWGCLVALGVPIIYNRA
MGEF-DKKKADRCFAFGLFMSLLMGVILFVTFMVIGDAYLRFYEP---SS--IVFGAAKD
YFFWYKFTFLLLPLYT-LMYVMVLADGDETLSMVSGIVQIVGNIVCSIVLVKF-------
IGIAGIGLGSFIGTVAAILVSFAHLLR-------QGNS------------LKLGFYFS--
-F--RWLIDVVKYSAVDAGSYLFLA---FYIAVMNRFITFA------YGPEMLVLGAIVL
FIKE-IQVLFDGVGESFSPLMNIYLGEESYDAVKKCYRLSQKTAVVEGLALTLLLLLLAP
YVVKLY----DISDP-L----MFSYAVG--GARIEVLGLVFLSLLYLLSSYYLLIDKIKL
GFMMSALRDVLVVTPV----CVFLGYF--------FGVYGM----FAGIAV-SPVLAYVI
SVLYIRIRYGA------------------------------ENYPL--LLADKLKGFKHK
FYELKLDPASIVKTQQQAEKFLCENGVDRKIVSKVKLLIEDIYMLIYEKNGADKAVYAEC
TVIIRETGVQIITKDDGILFDLSSDDVIAGSIVEFMVSGYMEKLKENKKYLTTMSYNRNT
FKVNNEVRV
>NZ_GG696046.1|c1|101467-103212|-|ZP_04855987.1|predicted_protein
------------------------------------------------------------
--------------------------------------MEERNNRLLNAKLNKYIVPGIM
MSLALQLGNIVDTIFVS--NLIGVEA-M-SAVTLSLPVETIVQLTGYCLGIGGSIAVGNM
LGKR-DKEGASKLFSATFIVTLVVGIIFSICALPAAEPVARLLVSG--DG--VLTGYTRD
YIRVSMLGAPVIGIGL-MMVNYLGVENHPELASAYLIAANVINLVLDYIFLRYTP-----
LGITGASLSTVLGFLFAMGIFVLYIRS---D---KRNL--------------HLILLKPG
EL--GITKEAIITGVPMLIFMAANF---VKALGLNTIIMNQ------LGEEGMAVFTVCD
NVLLIVEMLTGGIIGVIPNVAGILFGEKDYVGIRVLCKKMLKYSYILLAVIFVFIMLFTE
EITVMF-----GSGGGE----LGSHMVQ--ALRIFALCVAPYLWNKFIISYYESIEETAI
ASFATFLENAVVVLPA----TLVGILVWKQIDG--IGIDGI----AAGFVA-TEIITAVA
ACIFRKIRHKNTSFYIVPDKNPGINLDFSIKSTMEEAQTVHKRIIEFCQEQGASKSKANL
AAVCAEEMTVNIIRFGGKTSNWIDINLCLEDDLCRLRIRDNGVNFNPLEYQYDSEDFDIH
GIELVKKVSKSMDYIRAIDMNNTIISF---------------------------------
---------
>NC_004431.1|c2|2274181-2275620|-|NP_754348.1|hypothetical_protein
------------------------------------------------------------
-------------------MTVNKLEPDNGTPNDELFTVAGMFDGSLYKLLLRMALPMFV
GMLTQVTYAIADIFWLSHIDVTNSGI-I-AGVGLVFPVGMGLFAIANGIQIGMGSLLSRA
IGMQ-RLDRAQRILSVGIIIALFFAIVITVLGYVYAQPLLRSLGA---TK--SIIGYATE
FYYYSLLTVFSIMLIG-VMMGLFQGAGKIMVIMKASLLGALVNIMLDPIMIFVFD-F---
-GVKGVALASFLAQLSMVAYFIYTLMG---L---HIGL------S-IR---IALRPFS--
-W--KIYREFLSVGMAQMLMQLIIA---VGIVIYNFFIVRL-------DVNAMAAFTLTG
RIDYFIITPMLAIATALLTVVGQNWGHGNVTRTLNAYWAAVALAFSIVLVLAVMHIVLAP
WMYPLF-----TRVV-A----VSDYAVL--QTRIMALALPFVAISLLASEYYQAIGKPWY
SVLLTLMRHVFISVPV----VYLLAIVL-E-----MRITGV----YFGAMS-GTFVAAL-
--LAWRLLRLS------------------------------PRLLR--WNQEAVRSQHLD
MEVAP-------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ADKM01000164.1|c1|67366-68703|+|ZP_06719458.1|MATE_efflux_family_protein
------------------------------------------------------------
------------------------------------MKDNDFTSGAILPKLLKFMLPVLF
AMFLQSLYGAVDLLVVG--RFSDNSA-V-SAVSTGSQIVLTLTNILVSFSMGITVSVGQK
IGQK-RPEDAAKTIGTGLLIFAVVGIMLTILCLVGAEMLAKIMNA---PA--EAFKVTSS
YIRICGSGFLIITAYN-LLGSIFRGLGDSRTPLTAVGIACIFNIIGDIFFVKKLHM----
-GASGAALATVLAQLISVLISLVIIRR---T---ELPF------E-FR---KSHIKFD--
-K--PCAVSIFRIGTPIALQDLLVG---ISFLVMLAIVNDI-------SLTASAGVGVAE
KVCAFIMLVPAAFMQSMSAFMAQNYGAGKYDRASKALKTGIAVSFVFGVIMFLLTFFRGD
LLAGIF-----SNDS-E----AVANAWD--YLKAYAIDCLLTCFLFCFIGYYNGIQRTTF
VMIQGICGAFMVRIPV----ALIMQRV--------GGGSLF----HIGLATPCSTVLQI-
-ILCFAVYRRF----------------------------SQNKSAA--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NW_002196525.1|c2|177820-179268|+|YP_002252793.1|multidrug_efflux_pump_protein
------------------------------------------------------------
----------------------------MSGEAAARSAPARMTDGPIAGTLLALFLPILL
SNLLQALSGSINAMWVG--HALGEAA-L-AATANGSAVIAFVVSVVMGIGMAASILIGQR
LGAQ-DLAQAKRIVGTGATFFVGLAALIALAGVVLTGPIVARMQT---PP--AVQPLAVA
YLRVLFLAMPFQTATL-FLTILLRSTGDSKTPFRFQVVSVALDVTLNPLLIAGWGPM-PA
LGIAGSATATLLAQAIGLTLLARRLHR---T---RHML------C-LRADEAHLLRPD--
-P--RILKALAVKGLPMGLHMAVVS---LAMV--ISLVNHF-------GAQLSAAYGACL
QLWNYIQLPVMAMGMAVTPMAAQNLGARRLDRVRRIARTGIALNIAMAGGMVLVIQCFSR
AVLGLF----LPAEP-Q----TLQAAQH--INAMVAWAFIPVGVTFVLGSIIRASGTAVP
PLVILFLALWGIRQPA----AVLLMGT--------WGADAL----WFSFGL-GAVSSMLM
SLAYYRWAGWR------------------------------AAFMP--LVASASPADRAV
DQLREDQGTARC------------------------------------------------
------------------------------------------------------------
---------
>NW_002196569.1|c1|3214317-3215180|+|YP_002261126.1|multidrug_efflux_pump_(partial_sequence_c
------------------------------------------------------------
------------------------------------------------------------
---------------------------M--------------------------------
------------------------------------------------------------
----------------------------------------------------------PA
LGIAGSATATLLAQAIGVTLLARRLHR---T---RHIL------C-LRADEAHLLRPD--
-P--RILKALAVKGLPMGLHMAVVS---LAMVMMISLVNHF-------GAQLSAAYGACL
QLWNYIQLPVMAMGMAVTPMAAQNLGARRLDRVRRIARTGIALNIAMAGGMVLVIQCFSR
AVLGLF----LPAEP-Q----TLQAAQH--INAMVAWAFIPVGVTFVLGSIIRASGTAVP
PLVILFLALWGIRQPA----AVLLMGT--------WGADAL----WFSFGL-GAVSSMLM
SLAYYRWAGWR------------------------------AAFMP--LVASASPADRAV
DQLREDQGTARC------------------------------------------------
------------------------------------------------------------
---------
>NC_012660.1|c2|2751363-2752718|+|YP_002872127.1|putative_transport-related,_membrane_protein
------------------------------------------------------------
--------------------------------------MQSPLQRPLWQIYLIFLAPMVL
SNFLQSFSGTLNGIYVG--QMLGTQA-L-AAVSGMFPIVFFFIALVIGLGAGASVLIGQA
WGAQ-ETAMVKAITGATLTLGALVGVIAAVLGSLFARPALQALGT---PV--DVLDDAVG
YAQKMMLIMPLLLVFI-LYTQLLRGVSDTISPLLALMVSTLVGLLLTPALIRGWVGL-PP
LGIQSAVYAGLVGNALAMLFLILRLRH---K---NHVM------A-PDRELLAALRLD--
-R--VILGKVLRIGLPTGLQMVVLS---LSELVILALVNGH-------GSQATAAYGAVT
QIVNYVQFPALSIAITASILGAQAIGAGRLERIGPILRTGLLINTCLTGGLIVLGYVLSH
WLLGLF-----ITDD-A----ARVNAEH--LLHIMLWSILVFGFQAVIGGIMRASGVVLM
PVVISIFCVLCVELPM----AYLLNAH--------FGLEGV----WMAFPV--TYLAML-
-VLQTAYYRLV------------------------------WRHKQ--IKRLV-------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACLT01000095.1|c1|11095-12495|+|ZP_04319855.1|MATE_efflux
------------------------------------------------------------
--------------------------MKSSLDNIQESEKSQNQGQTIWKSMSMFLVPLLL
SNILQSVGQLFGMVVVG--RWLGVND-L-AAISAFFPLFFLLVSFVIGIGSGSSILIGQA
FGAR-NEDRLKAIVGTTLTFTFIIGAILAVVGSIFALNIMRLMGT---PE--NIIDMSVH
YARILFISMPVLFLYF-AYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGI-PK
FDVYGAAYASVISTIVTFVVMLIYLKK---K---NHPL------Q-LDETVRKYLRMD--
-W--DLLKLLLRLGIPASINMILIS---LSEIAVIAFVNRF-------GSDATAAYGVVN
QVASYVQMPAVSLGITVSIFAAQSIGANQFNRLQKVIRAGIVMNYIIGGILITLIYLFSR
EILALF-----LTSP-N----TIEIAHS--LVMITLWSYLIFGHAQIIGATMRASGTVLW
PTVIGVVSIWLVEVPV----AYYLSYHA-N-----FGIKGI----WIGYP--AAFIVSL-
-LLQYGYYKLS------------------------------WQKKR--ISRLVS------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_000964.3|c4|2000960-2002351|-|NP_389719.2|putative_efflux_transporter
------------------------------------------------------------
-----------------------------METSQEPLVTQKKSKPSVWRSMSLFLVPLLL
SNVLQSVGQLVGMMAVG--RWLGVDA-V-AAVSSFFPLFFLLISFTIGIGSGSSILIGQA
YGAK-NEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGT---PE--NVIHVSAN
YARILFYAMPFMFLYF-AYTTFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGF-PK
LGIYGSAYATVISTIATFLVLMVYLRK---R---KHPL------Q-FDKTVRRYLKMD--
-K--ELLVLLLRLGVPASINMILVS---LSEIAVISFVNHY-------GSNATAAYGVVN
QVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGGVLIILIYVFSH
QILSLF-----LTEQ-E----TLYIAHR--LLMITLWSYLLFGNAQIISATMRASGTVLW
PTVISIFAIWGVEVPV----AFVLSHYT-K-----LEILGV----WVGYP--AAFAVSL-
-LLIYGYYQFV----------------------------WKKKQIT--RLIQ--------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009725.1|c5|1972055-1973443|-|YP_001421443.1|YoeA
------------------------------------------------------------
------------------------------MEVQDHLETAEGRGQSVWRSMSLFLVPLLL
SNVLQSVGQLVGMVFVG--RWLGVDA-L-AAVSSFFPLFFLLISFTIGIGSGSSILIGQA
YGAK-NEERMKAIVGTTLTFTFMLGVVLAVVGSVFTLDILRLMGT---PE--NVIDVSVR
YARILFCAMPLMFLYF-AYTTFLRGTGDSKTPFYTLIVSTVINIGLLPLLILGLFGL-PK
FGIYGSAYATVISNIVTFIVLMVYLRK---R---KHPL------A-FDRTALRSLKMD--
-K--KLLALLLRLGIPSSINMILVS---LSEIAVISFVNHY-------GSNATAAYGVVN
QVASYVQMPAVSLGIAVSIFAAQSIGANQFGRLKQVIKVGIGLNYLIGGVLIVLIYTFSR
QILALF-----LTDQ-D----TLHIARN--LIMITLWSYLIFGHAQIVSATMRASGTVLW
PTIISIFAIWGIEVPV----AFILSHYT-N-----LGILGI----WVGYP--AAFVVSL-
-LLQYGYYRFV----------------------------WKKKQIT--RLIQ--------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABWN01000037.1|c1|22024-23403|-|ZP_05792921.1|MATE_efflux_family_protein
------------------------------------------------------------
-------------------------------MSKRNTKELDMLNGKTAGKLIMFAIPLAL
SSILQQLFNSADVAVVG--RFAKGNA-M-AAVGSCVALVGIFVNLIVGLSVGPNASLATI
IGQK-RRDDINGMLHTIMTFGAILGIVLMGIGIGTAKVILEISGT---PE--GVLPEALL
YIRIYFISIPFMVIYN-FGAAILRSFGDTRRPMFYLIITGVVNVALNLFLVICCKL----
-GVAGVAIATLISNVLSAILVMVYLCR---R---KDEF------K-FC---FRNMRIE--
-S--KYLKNILKIGIPAGVQGAIFS---ISNVFIQSGINSF-------GEDAIAGSSLAL
NFEYFTYDISNAFAQAAVTFISQNFGACNIKRCKKIFWQCMAFGICFTEVLAVVFMIWDD
FFVSIY-----TTSS-A----IAAFGLI--RMHHVCALEGLTATYEVESAALRGMGKSLG
PAIITILGTVVFRIIW----LVTVFRL--------VPTYTM----LMNVYIASWIFTGG-
-AIFILLAVHM------------------------------KKIML--IHGSGKISPLK-
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ADKM01000164.1|c1|55363-56721|+|ZP_06719447.1|MATE_efflux_family_protein
------------------------------------------------------------
-----------------------------------MNKNMDMLHGTIGDKLMTFALPLAA
TGILQQLFNAADIAVVG--RCVGKNA-M-AAVGSNTPVTALILSLFTGISIGANVVISTL
IGQR-KPEKVNKAVHTALLFAFVGGVIFALICELLSRQILSRMSI---PD--EVFGMALL
YFRVYVAGMPVILLYD-FASAVFRSHGNTRTPLICLLTSGVINVLLNLFFVLVLK-----
MTVNGVALATVISNLISSVLLIFFLMR---E---KSEI------H-FS---FKKLGID--
-K--KQLSMMISIGLPAGIQGMVFA---ISNIIIQSSINKL-------GSDVMAASSAAF
NIEIFAYYILNSFGQACTTFVGQNYGAKQPERCIKATKIALAQDMVITVVMSMLILLAGR
PLLYIF-----NSNE-A----VISVGMI--RMKYVLLSEGINVIIEIMSGCMRGYGRSFI
PALICTAGICGVRITW----VYKVFVHH-------KTYATL----LKAYPL-SWAATCA-
-ALVIAYTILR------------------------------RVTMK--DFFEGKSA----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_013592.1|c2|1563104-1564519|+|YP_003332957.1|MATE_efflux_family_protein
------------------------------------------------------------
-----------------------------MSPEIANEKPNALLQGSILRSLAKIGVPVIF
ANLLQSGYIMIDAFWVG--R-LGDKA-V-AAISVSQPIIFLAFALGIGLSVAGTTLVAQC
IGAR-LYQRANDIAAQVFTLSILFSIPIAVAGYFLAPWMLRALGA---QN--EVFPYALS
FLRVIISGIIFTFGFS-MLQSLMRGAGEVRIPLLITLGTLILNAIMDPLLIFGYGIV-PA
FGVAGAAIATLINQGIAMIAGLLVLRF---G---RVGL------K-IY---FRAMKPK--
-M--DMVKSVARLGMPASIELCAHA---LGASGMMTLVTGL-------GTDVTAAYGVVI
NINALVIVPAIGMSIATATLVGQNVGAGQSERARAIGRLSGAISFLILTVIGLIGVVFSP
YIIGTF-----APDQPM----VIAHGTH--FFHLIAPSYGLIGLQMALNGAFRATGRTMT
TMALALVSQWLIQIPL----AWGLSHYT-S-----LGVSGL----WWAFPITNLLMAGLT
IMFFERIDWQR------------------------------STLTH--SLGASAEKQPDT
V-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_003030.1|c2|3527902-3529260|-|NP_349946.1|cation_efflux_pump_(multidrug_resistance
------------------------------------------------------------
----------------------------------MKSLATDMTEGNVSKHLIKFAIPLIL
GNLFQLTYNASDSIIVG--RFVGKNA-L-AAVGIANPIMNIVMFFIVGICLGASVLMSEY
YGAG-NVKKLRREISTTVIAGFIFTVLIIIICVIFTEPILGLVKT---PK--EIIPEAAI
YLRIIFISLIFTFFYN-IYAAALRSIGDSKNPLLFLMISAVLNVVMDIVFVVWLK-----
MGVAGSAIATSVAEMMSCVFCIVYVHF---K---IPIL------K-FS---FKDMVID--
-K--GLLRSTVNYSWATAMQQTCLY---VGKFMVQGAVNPL-------GVNSIAAFNAVN
RVDDFAFAPEQSISNAMTTFLAQNRGANKYKRIKKGFLTGMKLETLYWCILVGIVYLGST
AIMKLF----VSGSEVK----VISIGSY--YLKLMAFFYLLPSWTNGVQGYFRGMGDMKI
TLRSTFSQIVG-RVAF----SYILAPR--------IGMVGI----AFSCLG-GWIVMLA-
-YEVPCLIKYR------------------------------RNFNN--KLSESSI-----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_012563.1|c1|352022-353392|+|YP_002802618.1|mate_efflux_family_protein
------------------------------------------------------------
-------------------------------------METDMTKGKPMGIIVRFFIPMFI
GNLFQQIYNIVDSIVVG--RFVGNEA-F-AAVGSCFLIMSFMTSILIGLAMGASAFFSQL
YGAK-QYDEMKKAISTSFFFILSISILLSLITNVFLYEIIELFQM---PK--DTVTYSAE
YLRYILTGLIFTGLYN-ICAYLLRSIGDSKSPLYFLIVSCILNTILDLIFVLVFN-----
MGVSGVGLATFIAQGLSALWCALYTVK-------HMKF--------LDF-KRKDIVFS--
-R--KLFKTILSYSVLTAVQQSLSS---FGMLMIQGLINTF-------GTTVMAAFAACS
KIDEFANRPLQDLSNAFSTYVAQNKGAGNIKRIRQGFHAILKVIALISFVISIVVFIFAP
NLISIF----VKKESID----IIQVGVG--YLRIVCIFYILLGCIVMFYGFFRGMGEVNI
SIILTVVSQ-GIRVAL----AYGLARTS-------MGFTGI----CWSIVI-GWFLSNA-
-LGGFMYKKVM------------------------------INAGQ--LYNTLEGLFKKT
K-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_012563.1|c1|396535-397152|+|YP_002802631.1|mate_efflux_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MTAVQQSLSS---FGMLMIQGLINTF-------GTTVMAAFAACS
KIDEFANRPLQDLSNAFSTYVAQNKGAGNIERIRQGFYVILKVIALISFVISIVVFIFAP
NLISIF----VKKESID----IIQVGVG--YLRIVCIFYILLGCIVMFYGFFRGMGEVNI
SIILTVVSQ-GIRVAL----AYGLARTS-------MGFTGI----CWSIVI-GWFLSNA-
-LGGFMYKKVM------------------------------ANSIQ--LYR---------
------------------------------------------------------------
------------------------------------------------------------
---------
>FP929051.1|c1|1254379-1255743|+|CBL15475.1|putative_efflux_protein,_MATE_family
------------------------------------------------------------
--------------------------------MNGSKSVRNLTQGKISSQILFFAIPVII
GNLLQELYNVVDTLIVG--QTLGEIK-L-AAVGSTSSLNFFALGFFIGLSAGCSVITSQH
FGAN-DMERVKKSVAAHIIIGVVSAVVLTVSFVLLVNPLLTMLGT---TS--DTFEYASR
YLTIIYLGIPATMLYN-LTASLLRSVGDSKTPLYLLLFSSVMNVGLDLLFIIVFR-----
WDVSGAAIATVISQLVSAVLCCVYIFF-------KVKM--------LLPNRNSFKNLT--
----STVRDELKVGFPMGLQNSVIS---IGMMVLQYFVNQF-------GSYAVAAYTIGN
RVQLLIQNPMNSMSTVIATFAGQNEGAGRYDRIKKGVNFCLLICIAYSIVIGAVSMIFAQ
PITGIF--TS-GSSQ-Q----TIDYSIQ--FMFWNCPFEWSLAMLFIYRGTIQGLKNGIV
PMIGSLIEVVMRIMTP----VIFSSV---------IGYASI----CVAGPA-AWTGSML-
-LMIAVYYVKI------------------------------RKLSK--TKTVVAN-----
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACPD01000003.1|c1|28224-29573|-|ZP_04803856.1|MATE_efflux_family_protein
------------------------------------------------------------
--------------------------------------MTDLTKGNTLKLIITFAIPILI
GNLFQQLYNLIDTVIVG--QTLGVKA-L-AAVGATSPIIGLLLSFAIGMTNGYSVVIARF
FGAN-DIKEMKKAVAGTVVLGLATSILFTVVSLIGIRPVLRILAT---PD--DVIDGAYS
FARIIIMGLTFSMLYN-MFSSVLRALGDTKSPLYFLIISTVVNIILDYLFICGFG-----
MGVEGAAFATVLSILLSAVLCFIYILK-------NYPI--------LRL-KKEDFNLN--
-R--SIIMDLFSTGISMGLMLSVVA---IGTVILQNAINGF-------GTETIAAHTAAR
KITEMFMLPLSTVSVTAATFSSQNYGANKPDRIKKGFIQLILISWVWSTVVVIMSFTIVP
LIVSGI--TG-TAET-E----IIDTATR--YLRIDTPFYYVLGILLVLRSAMQGIGQKVV
PIMASVIELVGKVIAA----YYLAPK---------LGYLGI----CITEPI-IWIACAL-
-FLVIKGFGIM------------------------------QKGMA--FSPQSQAE----
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABGF01000008.1|c1|70970-72340|+|ZP_02716228.1|DNA-damage-inducible_protein
------------------------------------------------------------
---------------------------------MNKKRTVDLIHGPILPSLLSFAFPILL
SNIFQQLYNTADVLIVG--RFLGQES-L-AAVGATTAIFDLIVGFTLGVGNGMGIVIARY
YGAR-NFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQYLDT---PA--EILPQSYQ
YISMIVTCVGVSFAYN-LFAGLLRSIGDSLAALGFLIFSALVNVVLDLYFITQLH-----
LGVQSAGLATIISQGLSAVLCFYYIRK---S---VPEL--------LP--RFKHFKWN--
-K--SLYVDLLEQGLAMGLMSSIVS---IGSVILQSSVNTF-------GAVIISAQTAAR
RIMTFALLPMTAISASMTTFASQNLGAKRPDRIAQGLRIGSRLSISWAVFVCIFLFFASP
ALVSFL---ASSTDG-Y----LIENGSL--YLQISSAFYPILSLLLIYRNCLQGLGQKIL
PLVSSFIELIGKIVFV----VLIIPW---------AGYKGV----ILCEPL-IWVAMTV-
-QLYFSLFRHP----------------------------LIKEGKA--ILATKVQS----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_011900.1|c3|1899370-1900740|-|YP_002511821.1|putative_drug/sodium_antiporter
------------------------------------------------------------
---------------------------------MNKKRTVDLIHGPILPSLLSFTFPILL
SNIFQQLYNTADVLIVG--RFLGQES-L-AAVGATTAIFDLIVGFTLGVGNGMGIVIARY
YGAR-NFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQYLDT---PA--EILPQSYQ
YISMIVTCVGVSFAYN-LFAGLLRSIGDSLAALGFLIFSALVNVVLDLYFITQLH-----
LGVQSAGLATIISQGLSAVLCFYYIRK---S---VPEL--------LP--QFKHFKWD--
-K--SLYADLLEQGLAMGLMSSIVS---IGSVILQSSVNTF-------GAVIISAQTAAR
RIMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGLRIGSRLSISWAVFVCIFLFFASP
ALVSFL---ASSTDG-Y----LIENGSL--YLQISSAFYPILSLLLIYRNCLQGLGQKIL
PLVSSFIELIGKIVFV----VLIIPW---------AGYKGV----ILCEPL-IWVAMTV-
-QLYFSLFRHP----------------------------LIKEGKA--ILATKVQS----
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_003098.1|c3|1723401-1724771|-|NP_359348.1|MATE_efflux_family_protein_DinF
------------------------------------------------------------
---------------------------------MNKKRTVDLIHGPILPSLLSFTFPILL
SNIFQQLYNTADVLIVG--RFLGQES-L-AAVGATTAIFDLIVGFTLGVGNGMGIVIARY
YGAR-NFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQYLDT---PA--EILPQSYQ
YISMIVTCVGVSFAYN-LFAGLLRSIGDSLAALGFLIFSALVNVVLDLYFITQLH-----
LGVQSAGLATIISQGLSAVLCFYYIRK---S---VPEL--------LP--QFKHFKWD--
-K--SLYADLLEQGLAMGLMSSIVS---IGSVILQFSVNTF-------GAVIISAQTAAR
RIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
ALVSFL---ASSTDG-Y----LIENGSL--YLQISSTFYPILSLLLIYRNCLQGLGQKIL
PLVSSFIELIGKIVFV----VLIIPW---------AGYKGV----ILCEPL-IWVAMTV-
-QLYFSLFRHP----------------------------LIKEGKA--ILATKVQS----
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABAF01000008.1|c1|66251-67621|+|ZP_01833503.1|MATE_efflux_family_protein_DinF
------------------------------------------------------------
---------------------------------MNKKRTVDLIHGPILPSLLSFAFPILL
SNIFQQLYNTADVLIVG--RFLGQES-L-AAVGATTAIFDLIVGFTLGVGNGMGIVIARY
YGAR-NFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQYLDT---PA--EILPQSYQ
YISMIVTCVGVSFAYN-LFAGLLRSIGDSLAALGFLIFSALVNVVLDLYFITQLH-----
LGVQSAGLATIISQGLSAVLCFYYIRK---S---VPEL--------LP--QFKHFKWD--
-K--SLYADLLEQGLAMGLMSSIVS---IGSVILQSSVNTF-------GAVIISAQTAAR
RIMTFALLPMTAISASMTTFASQNLGAKQPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
ALVSFL---ASSTDG-Y----LIENGSL--YLQISSAFYPILSLLLIYRNCLQGLGQKIL
PLVSSFIELIGKIVFV----VLIIPW---------AGYKGV----ILCEPL-IWVAMTV-
-QLYFSLFRHP----------------------------LIKEGKA--ILATKVQS----
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABFS01000011.1|c1|12565-13935|-|ZP_02709190.1|DNA-damage-inducible_protein
------------------------------------------------------------
---------------------------------MNKKRTVDLIHGPILLSLLSFAFPILL
SNIFQQLYNTADVLIVG--RFLGQES-L-AAVGATTAIFDLIVGFTLGVGNGMGIVIARY
YGAR-NFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQYLDT---PA--EILPQSYQ
YISMIVTCVGVSFAYN-LFAGLLRSIGDSLAALGFLIFSALVNVVLDLYFITQLH-----
LGVQSAGLATIISQGLSAVLCFYYIRK---S---VPEL--------LP--QFKHFKWD--
-K--SLYADLLEQGLAMGLMSSIVS---IGSVILQFSVNTF-------GAVIISAQTAAR
RIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
ALVSFL---ASSTDG-Y----LIENGSL--YLQISSAFYPILSLLLIYRNCLQGLGQKIL
PLVSSFIELIGKIVFV----VLIIPW---------AGYKGV----ILCEPL-IWVAMTV-
-QLYFSLFRHP------------------------------LIKEG--KAILATKVQS--
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_010162.1|c9|4458359-4459735|+|YP_001613833.1|MATE_efflux_family_protein
------------------------------------------------------------
--------------------------------------MKDLTQGSIARHIVTMAVPIAV
GMIFQTLYYMIDLYFVG---ELGDVP-L-AGVSAAGNATFLVLALTQVLGVGTVAMISQA
VGRK-DRDEANVVFNQSLTLAAVSGLAVLVLGYLTTTPYMRSVAA---DA--ATVEAGRT
YLFWFMPGLALQFALV-AMGSALRGTGLVQPTLVVQLLTIVLNAILAPILIAGWGTH-RP
MGVAGAGLASTLSLVVAVIALWAYFRR---L---ERYV------G-VS---APLLRPR--
-L--PIWRQLLAIGLPSGGEFALIF---VYSAIVYWTLREF-------GSAAQAGYGAGS
RLIQGLILPAMAVSFAAGPIAGQNFGAKLADRVRSTFSISAAIISALMVLLTLFVGWRAE
ALIGSF-----AKNA-D----SIAVGAQ--FLRFACWNFVAQGLIFTCSSIFQGLGNTTP
SLLSSGARLVTFAVPA----IWLSTLPG-------FRIELV----WYLSIA-STTLQAIA
SVLLLRAEFKQ------------------------------RFVPG--FVASGAGLGANS
------------------------------------------------------------
------------------------------------------------------------
---------
>FP929038.1|c1|180758-182101|-|CBK79134.1|putative_efflux_protein,_MATE_family
------------------------------------------------------------
---------------------------------MTAADTSYMKEKPVLSLLLSMGIPMML
SMLINSLYNIVDSIFVA---RMSEDA-M-MAISLVYPVQNLLHSIAVGFGVGTNAVIAIF
LGSR-KGDAASSAASQGILLNLCHGLLFMVFGILFMRPFLNMFTS---NE--TVIAYGMQ
YGIIVLCFSMIHTTEL-SFEKIFQSVGRMKTSMISLGSSCMINIILDPLLIFGIGPF-PE
MGIRGAALATGIGQTTGLCIYLLTSRI---K---PLNL------Q-FK---MQYFKPD--
-K--NICRRLYGIGIPATLNMALPS---FLISALNILLGTF-------SDTQVLVLGIYY
KLQSFLYLPANGMIQGMRPIMSYNYGARESSRVRSIYQTALYIIILILLAGTVLCLAVPD
QLIHLF-----SDNT-E----TIVAGRR--ALRIICIGFAVSAVSVVTEGALEAMGKGIH
SLLISCMRYIVLILPL----AFIFSHF--------FGVNGV----WHAFWI-TEVITAV-
-TSGLIFYRQY------------------------------RAIA---------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009706.1|c4|3551188-3552549|-|YP_001396865.1|cation_efflux_pump
------------------------------------------------------------
-------------------------------MENNLTNQYYLESAPILKSIAHLSIPMMI
GMSVGTIYNIINAFFIG---LMHNTE-MLTAVTLGLPIFTILMAFGNMFGVGGGTFVTRL
VAKK-EIEKAKHIAGYIFYSSIIASTCIAIIALFIINPLVKILGA---DT--STIAYTKS
YSLTMFFGGFATVLNF-ALQQIVRAEGASKESMYGMIISTILNFIFDPLFILLLN-M---
-NVVGAALAMILANLGSSIYYIYYLEI---K---SEHL------K-GF---IHCFKIS--
-F--QDKMEIYKIGVSELLMTVFLI---ITTLLLNNFSIAY-------GDNVVAGFGIAL
RIVQVPEFLSMGLYLGIIPLIAYNFSNRNFERLKNGIRQSALCIAVLSIIFIGVVYIFTM
PIIQLF-----SNDS-S----VISIGTY--IMTAMFISALFNGFTGLFTGIFQASGQGIP
TTIMSV-TQGILYIPV----IIVLHNL--------FGLHGV----IWSMTVTEIITCVIG
GIFYIHFNSKI------------------------------KDLKV--KEAF--------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACNH01000169.1|c1|16499-17920|+|ZP_04094222.1|MATE_efflux
------------------------------------------------------------
-----------------------MAKSNSKSKKETSNLEEEILRGPIIPISIKLAMPILI
GQFLLLIYGVTDTIFISMLDKSSTAL-M-SGIGLVFPVYMLFLALGTGMFTGVSSLLARG
IGEQ-NKHVINKAADSGLVLSSIAAFVTVVILYIIGEPMLNFLAGNQLSQ--EAVNYASQ
YFYFIIPGLGLIMVYQ-ALLGVLQGEGLSQYYGISMLISTVFNIILNPIFIFVFD-----
LGVAGSALATTVSITISLLFVLSIFKS---G---KSSM------H-IS---FNFSNID--
-K--EQILEIIRIGIPQVLSMVSLS---FAMMFLNNLIGSI-------SETSMNSWVLVG
RMDEFILMVGYAFSGATLTLIGQNYGRKNYSRVLEIFKKNVILGIVLSSIFVLIYVFGSK
NLFSLF-----TTLP-E----VVEGAVL--QVKTVSITYVCIVTAIVVTASFQATGKAMP
GLIIDIIRMGVVTIPL----AYLVVYQF-N-----KGVVDL----FYVIAGANIFTMFL-
-SVIWCYSYLK----------------------------KQERKMP--TVSQELKH----
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACLU01000144.1|c1|56414-57613|-|ZP_04315029.1|MATE_efflux
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MLFLALGTGMFTGVSSLLARG
IGEQ-NKHVINKAADSGLVLSSIAAFVTVVILYIIGEPMLNFLAGNQLSQ--EAVNYASQ
YFYFIIPGLGLIMVYQ-ALLGVLQGEGLSQYYGISMLISTVFNIILNPIFIFVFD-L---
-GVAGSALATTVSITISLLFVLSIFKS---G---KSSM------H-IS---FNFSNID--
-K--EQILEIIRIGIPQVLSMVSLS---FAMMFLNNLIGSI-------SETSMNSWVLVG
RMDEFILMVGYAFSGATLTLIGQNYGRKNYSRVLEIFKKNVILGIVLSSIFVLIYVFGSK
NLFSLF-----TTLP-E----VVEGAVL--QVKTVSITYVCIVTAIVVTASFQATGKAMP
GLIIDIIRMGVVTIPL----AYLVVYQFN------KGVVDL----FYVIAGANIFTMFLS
VIWCYSYLKKQ------------------------------ERKMP--TVSQELKH----
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_AAUW01000008.1|c2|274474-275889|+|ZP_01547729.1|MATE_efflux_family_protein
------------------------------------------------------------
------------------------------MKDQEPATEAKFLSGSLFRHVTVMSLTASV
GLMAIFAVDFVDMIFIS---MLGKAE-LAAAVGYAGAILFFTTSFNIGVAIAAGALVARA
LGAG-DKEDARQQASNALTAGVLFSAVFALAVWFSLGPLVTLMGA---TG--RTHDLAVH
YLAIIVPTLPLLLLGM-AGGAVLRAHGDARWAMMSTIIGGLVNAVLDPILIFGFD-L---
-ELTGAAIASAASRVAIAVFALVPIVR---F---HGGL------S-LP---RPMALVR--
-G----MPSITAIACPAILTQLATP---VGQAWVTRSMAEF-------GEEAVAGMAVVA
RMTPLAFATIFALSGAVGPIVGQNYGAGRFDRVRDTLRAALLFTALVVGLAALVLFLLRG
PVAHLF-----EADG-V----ALTLIYL--FCGPLALAFFFNGAIFVANACFNNLGRPFY
STLLNWGRHTAGTIPF----VLVGGML--------YGAPGV----LIGQAA-GGVLFGVA
AVLIVRSVIRS------------------------------VEEHH--EKPAKQGLFQRQ
ARQLILFFSRR-------------------------------------------------
------------------------------------------------------------
---------
>NZ_ADCC01000024.1|c1|1088-2440|-|ZP_06228679.1|efflux_transporter_inner_membrane_protein
------------------------------------------------------------
-----------------------------------------MAHDRLLPLILRLALPSVI
GVTVSAAYQLLNAYFVG---RLGTAA-L-AAMALSFPFAMCITAIGQIFGAGAASLIARS
LGRA-DDHSANDYASHALWSAMIIAGITAIAGWQLAPTLLTWLGA---GP--SILPLAVA
YLHWLLAGYVAVVFNM-VCGFIVRADGNTVLSMTTQVSSFAMNAALDPVMIFWFG-----
LGIEGAGIATFLAQLCGLTLYWRHFAG---R---HGAI------------VLSWPSVG--
-RCGCRLASIARIGIPPALNTLLAI---AAMSMLNAFAARY-------GEASVAAIGLAS
RLAMLAALPLYGLCSGAQSVVGFNVGAGNWTRVAQAVRAMVAVALTFAGVYAGSVVWQAR
TIIGWF-----AHES-A----TIEIGSR--AILLFHCALPVLGVQQVCLLFMQAKGNAIW
ATLVAVLRHGLFLMPL----MALLQHA--------YGQDGL----LFSVAAADMAAGLI-
-AMVILYSEMR------------------------------QIDKA--SRLCQVNGMGAV
E-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_010505.1|c2|1405503-1406915|-|YP_001754025.1|MATE_efflux_family_protein
------------------------------------------------------------
-----------------------------------MRRPVDLDQDRVVGLVLRLSGPAIL
GISAHALQMLVNAWFVA---DLGAAA-I-ATIALAYPVTLLVAALGYGAGIAAASQVSRA
LGSG-DRDRAAAAAGLGFWLSLPAGLAVTAAIVADTPFWLRLLGA---DA--ALAAEAAP
YTALATVGTALMLVMI-VGGFVVRGQGHARLSGAVMVGSFGLNILLDAVLIRVCG-L---
-GTVGAGWAAIGAQLAGAAAYGLHFAR---A---RGAD------R-VS---LRWPGGR--
-IGRGALAEALTLALPATGSSLLAA---VAMALFVEAAAPY-------GDAAVAAQGIAL
RLTLVAALPLLGTMAGAQAVLGHAAGAGRRDRLHRALAFVLAAALAYGLVVGGLMIACAE
PLAGLF-----AQDP-A----TARAGAR--ATALFAVAFMPVGLQLTAATLFQAIGAPRR
AAAVSLAAQGLALIPP----LLILPPL--------LGYAGVLASRVAAEFLADGLGLAL-
-LLAWGLDARR------------------------------AGGAAPVEGREAVQVAAAH
ETAHQGA-----------------------------------------------------
------------------------------------------------------------
---------
>NC_011983.1|c2|1082905-1084254|+|YP_002541154.1|efflux_transporter_inner_membrane_protein
------------------------------------------------------------
-----------------------------------------MNDPRVMRLVLTIALPAVA
GLAASAGHHAINAIFLG---ALGPEV-L-AGISLVMPLFLLVAATGQGLGIGLATLLARH
LGEG-DVPAASSVAVTALAATIPIGIVLSVLIYLGLPSFVGALGA---SN--ELLAPGLN
YGRLLAFGVTLGLLQA-VCDFIAIAEGNSRFSMIVLIASFALNAILDPVFIFLLQ-----
FRETGAAFATILSSVAALLCYVVYFQR---R---WGKV------------RVTMRLVH--
-W--QLLRPIARIGIPAAATSVVTG---VGFLVLLREAAVH------GGDAGVAATAIAI
RLMTLGQLPVFGFCLGAQSVVSHAVGAGDPLRVRAIIRVMLMVTIPVASLYSALLFLGAE
PIVRLF-----TDSP-E----VAAEAAS--YLRALFPVFPLAAFQSVLLVMLQSRGRAGL
SAVVGLAPQGYLLIPL----LLLLPLW--------IGFAGV----ALAPA--GAAILAA-
-ILGLVIARRE----------------------------WLALLPT--SPGQLIGQSTLH
P-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_011988.1|c2|750104-751516|-|YP_002547519.1|hypothetical_protein
------------------------------------------------------------
------------------------------MTSSTTKMAADLNDPRIKRLVMTVALPAVA
GLTASAAHHAVNAMFIG---ALGPQA-L-AGVSLVLPLFLLVSAATEGLGIGLATLLARS
LGQG-DVKAASSVAVTALVAAVPMGIVLSTLIYLALPAFVQAVGG---EG--DLLASGLI
YGRLIAFGVTLGMLQA-ICDFIAIAEGNSRFSMTVLIASFALNIALDPVFIFLLD-----
FREAGAAIATMVSTVAALLAYAVYFYR---R---KGNV------R------IDLSLIR--
-W--RLLKPISSIGIPACATSIVTG---LGFMVLLRQASQS------GGEAGVAAIAIAI
RLIAFGQLPVFGFCLGAQSVVSHAVGLGDDQRIKAAIRFMLMITIPVALCYSTLLLVAAG
PIARLF-----TQSP-E----VAEQTAA--CLRLLFPVFPLAAFQSVLLVMLQSRGRAGL
SALVGLAPNGYMLIPL----LLLLPAW--------LGFTGV----AIAPAT-AAVLTAA-
--LGIVVARRE----------------------------WATILPS--NLPSSDGPLPGL
SALHPETRGLS-------------------------------------------------
------------------------------------------------------------
---------
>AJ315451.1|c1|5635-7053|-|CAC48059.1|hypothetical_protein
------------------------------------------------------------
--------------------MNDMSDASGSFRRRQRLAPEDLASPQLFRLLLRLGLPAMF
GLSINAAHHTINMIFIG---MIGEDQ-I-AAIMIVLPVLMLVAAFGEGIGVGVATEVGRT
LGAG-NRSRAGAIASVSLAAGVVFGAASAIAILAF--PDLLLFGA---TP--ALQPLAQQ
YLMMIAVSVPLTMAQI-ILDFLAIAEGNARFSMWTLVACFALNMILDPIMIFGFG-----
FGLQGVAIATILSQLVALCIYAAYHAR---R---LGTV------R-LA---FGWQWRD--
-I--GYLRPVLAVGAPTTLTQSRDRRRDCGNGVARRHLSRR---------SRHRWRRDXL
RLLAVGTLPVIGISLGAQSILSFAWGRGDTARVLSAARILTAVTTAVSGTYGVAALAFSE
ELASFF-----TDDA-T----VIGIAAQ--AIVATHLPLLLFAAAN-GADPLPGSGQSES
GRCHRSGAEWLSSVSAAGSPAAVLRF---------FRLAGR----NVPGLCPDRPAVGR-
-LPDEELRALR------------------------------QRSAD--HLTSIRPYPSFC
P-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_008378.1|c1|339572-340993|+|YP_764827.1|putative_efflux_transporter
------------------------------------------------------------
--------------------MNDMSDTSGSFRKRQRLAPEDLASPELLRLLLRLGLPAMF
GLSINAAHHTINMIFVG---MIGDDQ-I-AAIMIVLPVLMLVAAFGEGIGVGVATEVGRT
LGAG-NRSRAGAIASISLAAGVVFGAASAIAILAF--PDLLLFGA---TP--ALQPLAQH
YLMIIAVSVPLTMAQI-ILDFLAIAEGNARFSMWTLVACFALNMILDPIMIFGFG-----
LGLQGVAIATILSQLVALCIYAAYHAR---R---LGTV------R-LT---FGWRWRD--
-I--GYLRPVLAVGAPTTLTSLATA---GAIAAVVSLAGTY------HGEAGIAGVGIAL
RLLAVGTLPVIGISLGAQSILSFAWGRGDTTRMLSAARILTVVTSAVSGAYGLGALVFSE
ELASFF-----TDDA-T----VIGIAGQ--AIIATHLPLLLFGLRQTVLILFQAQGRPKA
AVAIGLAQNGYLLFPL----LALLPPF--------FGFSGL----LAAMFL-ASALTGL-
-LSAGCLARTL--------------------------SALRQRAAD--HLTSIRPYPNFC
P-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_010997.1|c1|742633-744051|+|YP_001985312.1|efflux_transporter_inner_membrane_protein
------------------------------------------------------------
---------------------MNDMSEMSGSLRKRRLAPEDLASPQLFRLLLRLGLPAMF
GLSINAAHHTINMVFVG---MIGEDQ-I-AAIMIVLPVLMLVAAFGEGIGVGVATEVGRA
LGAG-DRSRASTLASVSLAAGVAFGAASAVAIVAFPSALL--FGA---TS--AIEPLAQH
YLLIIAISIPLTMAQI-ILDFLAIAEGNARFSMWTLVACFALNIILDPIMIFGFG-----
LGLQGVAMATILSQLVALSIYGAYHAR---R---LGTI------R-LT---FSWRFAD--
-I--RHLKPVLAVGAPTTLTSLATA---GAIAAMLSVAGTY------HGEDGIAGVGIAL
RLLAVGALPVIGISLGAQSILSFAWGRGDISRVLAAARMLSVVTSAVGGVVGLAAIVFSE
RLAAFF-----TDEA-A----VLSIAGQ--AIVATHLPFLLFGLRQTVLILFQAQGRPKA
ALAVGLAQNGYLLFPL----LALLPPF--------FGFSGL----LAAMFL-ASALTGL-
-LSCVCLARSL--------------------------AALRQRSAD--DLIALRPHPNFC
P-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_007766.1|c1|519260-520678|+|YP_473077.1|efflux_transporter_inner_membrane_protein
------------------------------------------------------------
---------------------MNDMSEMSGSLRKGRLAPEDLASPHLFRLLLRLGLPAMF
GLSINAAHHTINMIFVG---MIGEDQ-I-AAIMIVLPVLMLVAAFGEGIGVGVATEVGRA
LGAG-NRSRASTLASVSLAAGVAFGAASAVAIAAF--PSVLLFGA---TS--AIEPLAQH
YLLVIVVSIPLTMAQI-ILDFLAIAEGNARFSMWTLVACFALNIILDPIMIFGFG-----
LGLQGAAMATILSQLVALSIYGAYHAR---R---LGTI------R-LT---FGWPFGD--
-L--RHLKAVLAVGAPTTLTSLATA---GAIAAMLSVAGTY------HGEDGIAGVGIAL
RLLAVGALPVIGISLGAQSILSFAWGRGDISRVLAAARMLSVVTSAVGGVYGLAAIIFSE
RLAAFF-----TDEA-S----VLSIAGQ--AIVATHLPFLLFGLRQTVLILFQAQGRPNA
ALAVGLAQNGYLLFPL----LALLPPF--------FGFSGL----LWAMFL-ASALTGL-
-LSCFCLARSL--------------------------GALRQRSDE--PLTSIRPYPRFC
P-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_009937.1|c4|3740669-3742087|-|YP_001526160.1|efflux_transporter_inner_membrane_protein
------------------------------------------------------------
-------------------------MSGTGEDGVRFAAPLDLADPRLERLIVRLAVPSVA
GLSITALHHVANAAFVG---LLSGQA-L-AAVSIAVPIFALVAAIGHGLGIGGAASIGRL
LGAG-DALDAGRAASATLALCVLLGGAAGIGLFWGAGGVLALFSP---GP--DLAPIAAT
YLRLLAVSCPLLLAQI-ACDFIAIAEGNSRFSMWTLLGAFALNIVLDPLLIFGFG-----
LGVEGAALATILSQLAALAAYGLYFGR---R---WGRV------R-LG---VGGLGLK--
-A--RLLRPILAVGVPAGLSSALSA---LAFAVVYAMAGIH------GGDEAVAGVSIAF
RLLTLGLLPVIGFCLGAQPVLSFAAGAGDRIRLRAATLFMARVALGFTLFYAVSMMLGSA
PLVGLF-----TADA-R----VADVARR--GLILFHAGFALTGLHQVLVILLQAMERARL
AAVISLAPQGYLLLPL----LYGGAAL--------WGMDGV----LAAPPL-AMGLTAL-
-VSAALLLREV------------------------------RRLPT--ARSRKSSPSLAA
EGAGGSA-----------------------------------------------------
------------------------------------------------------------
---------
>NC_011666.1|c8|3649891-3651360|+|YP_002363589.1|MATE_efflux_family_protein
------------------------------------------------------------
-------------MNESFPVDAPRAPEQAPASDLFLPKPVDLGDPRLRSLIMRLALPSVF
GLSINALHQVVNAAFVG---ALGAEA-I-AAVTLALPIFIFISAVGHGLGVGAAASIGRL
LGAN-EPEEANATATVALALAAPFGVACAAALLLWLTPILELFGA---TP--TSAPFARA
YIGVLAFGAPFMLLQI-LCDFIAIAEGNTRFSMWTLVGAFTLNIILDPILIFGFH-----
LGVAGAAAATIASELAALAAFAFYFAN---R---VGRL------R-IG---AKWLRPR--
-F--AILRPIFSVGAPTSLSTALAA---VSFVLIYRAAANH------GGDAAIAGAGIAL
RLLTFGELPLVGFCLGAQAVLSYAFGAGQPARVVAATRFMLVVTTTFAAAYSLVILAFPH
TVISLF-----TDDA-P----TRAMAVQ--AVVAFHAVFALSGLQLVTLVLLQSLDEGRL
AGAVGLAPQGYLLIPL----LVALPPA--------FGMTGV----ILSQPI-AMALTAV-
-LSAVLLWRRI------------------------------GSLRR--EAAEDKGGADQA
SAQSGSTLMAEA------------------------------------------------
------------------------------------------------------------
---------
>FP929051.1|c1|1238052-1239812|-|CBL15460.1|Na+-driven_multidrug_efflux_pump
------------------------------------------------------------
----------------------------------MSSTVLGRNAVTVNKKYTEYFLPTVL
TAMATNIAMIVDSIIAG--NLLGQNS-L-AAINLMSPISQFYFSITILFGLGASSIISFA
KGRR-DEKQANRVFTSTFIVLIALSVIFIAIQLPLADSISSLLTK---DA--ELKSLLYQ
YYVPFIIGTPIYLLLM-CSIHFVRADARPAFASNIVIVANAVNLGLDFLFMGAFK-M---
-GIAGSSIATVTGYAVGFVMMSTHFIM---K---KSTL------H-FD---FSILRNPVQ
FF--KFLGKMVTIGLSGALGTMLIT---VKMLFLNTIIQSI------GGSAGMVSYSVCS
SSQIFMSMFITGASQTMIPIIGVCLGEKDYDGVRYAFRRAARVLAVSSVVIMLFICIEPE
PIIKFF----GITSP-T----DIANTVP--AMRINALSFPGLSFSFLLLYYYMATQKRAI
STAISIINGIVILIPS----ALILGKF--------FGIMGV----WYSLVVAQVGTLVV-
-VYFIDLAEKR---------------------------KSGGKYKNFYLLEETEDNELLA
LSFKGTKENAAGVSLYLSSFLSKNGIEESRANRIAVAVEEMAANCAERMEGKKKFADIDI
RIFADKKETIISVRDNGDEFDPLNDDKEFEMSPLTVVKAISDKVEYSRALGFNRTIIKL-
---------
>NZ_AAYW02000016.1|c1|129900-131045|+|ZP_02075315.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MMLASGGNAIISKY
LGEE-NKKRACESLTQFVTVCILVSLVIVVISQVFLTEISRLLGS---NE--VLLADCKS
YLGMVSLFIPACMLQT-LFQMYLVTAGRPTMGLLLMIGAGIVNAVLDYVLIVICD-----
MGVAGAALATGIGQCIPAIAGLVFFMF---S---KGEL------------RFTGFKLS--
-L--RELGHACYNGSSEMVSELSNS---VVTVLFNLVLMRL------AGEAGVAAISILL
YGQFLFNAFYLGFTIGISPIVGFQYGAKDKKKLRSIYKIAFLFVAVSAVILTVIAEVLAT
WIITVF-----THDP-A----TFELAEI--GFKIFAINFLFSGLNITSSGFFTALSNGKV
SAIISFSRTFIFTVLS----LLILPHF--------LKIYGA----WLAVPI-AEAVTLLV
TVPFHKVYFIG------------------------------KGEKN--YLRG--------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABDP01000006.1|c1|116058-117398|-|ZP_02617324.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MTNNIENKQGKFEELTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMNVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLVISFLTGTIIMIFGELYLNELALFLGA---TN--SLLSSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAIASGAVINCILDPIFIFYFN-----
LGIKGAAYATIIGEIISFIILIVVSGM-------RENI------K-FN---LKNFSIN--
-K--RILSELYGGGVPNFTREIFIG---ISLMLLNNELKIF-------GAEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEEALKFTLRSAIIFMAFISIIFLTYSK
NMILLF-----INDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGIKGI----LYVQPL-SDFITFV-
-ISVVLIAKYK------------------------------KS-----------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABKW02000004.1|c1|611407-612756|+|ZP_02995305.1|hypothetical_protein
------------------------------------------------------------
---------------------------MTKNIEEKQEKFEKLTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESKK-NRTESSKMAIDGLVISFLTGTIIMIFGELYLNELALFLGA---TN--SLLFSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAIASGAVINCILDPIFIFYFN-----
LGIKGAAYATIIGEIISFIILIIVSGM-------RENI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMAFISIIFLMYSE
NMVMLF-----RNDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMSKM--------LGIKGI----LYVQPL-SDFITFV-
-ISVVLVAKYK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_010520.1|c1|2786110-2787459|-|YP_001787899.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MIKNIEDKQGKFEELTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLAISFLTGTIIMIFGELYLNELALFLGA---TN--SLLSSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAITSGAVINCILDPIFIFYFN-----
LGIKGAAYATVIGEIISFVILIVVSGM-------RGNI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMVLISIIFLMRSE
NMVKLF-----RNDN-E----IVNIGSQ--VLSIQSITLPLIGYITIAGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGIKGI----LYVQPL-SDFITFV-
-ISVVLVAKHK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009495.1|c1|2723381-2724730|-|YP_001255077.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MTKNIEDKQGKFEELTKTPISKLILKMAIPSIM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLVISFLTGIIIMIFGELYLNELALFLGA---TN--SLLSSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAITSGAVINCILDPIFIFYFN-----
LGIKGAAYATVIGEIISFIILIVVSGM-------RENI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMVFISIIFLMYSE
NMVMLF-----RNDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGVKGI----LYVQPL-SDFITFV-
-ISVVLVAKYK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABDO02000007.1|c1|17630-18979|+|ZP_02615193.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MTKNIEDKQGKFEELTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLVISFLTGIIIMIFGELYLNELALLLGA---TN--SLLSSTKE
YLLILLIGNPFMISAL-TMNNQFRLQGNPSLGAAAITSGAVINCILDPIFIFYFN-----
LGIKGAAYATVIGEIISFIILIVVSGM-------RENI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMVFISIIFLMYSE
NMVMLF-----RNDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGVKGI----LYVQPL-SDFITFV-
-ISVVLVAKYK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009699.1|c1|2771294-2772643|-|YP_001391878.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MTKNIEDKQGKFEELTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLVISFLTGTIIMIFGELYLNELALFLGA---TN--SLLSSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAITSGAVINCILDPIFIFYFN-----
LGIKGAAYATVIGEIISFIILIVVSGM-------RENI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMVFISIMFLMYSE
NMVMLF-----RNDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGVKGI----LYVQPL-SDFITFV-
-ISVVLVAKCK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_010516.1|c1|2755917-2757266|-|YP_001782196.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MIKNIEDKQGKFEELTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLVISFLTGTIIMIFGELYLNELALFLGA---TN--SLLSSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAITSGAVINCILDPIFIFYFN-----
LGIKGAAYATVIGEIISFIILIVVSGM-------RENI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMVFISIIFLMYSE
NMVMLF-----RNDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGVKGI----LYVQPL-SDFITFV-
-ISVVLVAKYK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_012563.1|c2|2897865-2899214|-|YP_002805027.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------MTKNIEDKQGKFEELTKTPIPKLILKMAIPSTM
AMLIGIAYSLADTYFIS---KIDTIS-T-ASVGLAFSFMSVTQAFGLLYGHGSGNYMSRM
ESEK-NRTESSKMAIDGLVISFLTGTIIMIFGELYLNELALFLGA---TN--SLLSSTKE
YLLILLIGTPFMISAL-TMNNQFRLQGNPSLGAAAITSGAVINCILDPIFIFYFNL----
-GIKGAAYATVIGEIISFIILIVVSGM---R----ENI------K-FN---LKNFSIN--
-K--KILSELYGGGIPNFTREIFIG---ISLMLLNNELKIF-------GEEYIASFTIVN
RLVLAGTYLMVGLGHGFQPVCIFNYGAKLYERVEKALKFTLRSAIIFMVFISIIFLMYSE
NMVMLF-----RNDN-E----IINIGSQ--VLSIQSITLPLIGYITITGMFLQSTHKFKE
ATLITSSRQGYIYIPL----ILIMPKM--------LGVKGI----LYVQPL-SDFITFV-
-ISVVLVAKYK------------------------------KELKC--------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ADKM01000164.1|c1|34294-35682|+|ZP_06719434.1|MATE_efflux_family_protein
------------------------------------------------------------
--------------------------------MSSITEKNPLGYERIPSLLRKFAVPSII
AMLVSSLYNVVDQIFIG--QGVGMLG-N-AATNAAFPLTTICMAITLTIGIGTASRYSLY
LGQG-QEERAAQTVGCGICMMVLFGTVYAVITEIYLKQMLVAFGA---ID--KVLPYAVE
YTRITAIGMPFIVIMN-GMSNLARADGSPTYSMTTMIIGAVINTILDPIFIFGFK-W---
-GVAGAALATVIGQVISCVYAFMYIKR---L---KRIT--------LR---REHLRVT--
-P--KEMLTTAAMGMSNGLTQVAIT---LVQIVMNRSLVKYGELSEYGSAIPLAASGIVM
KVNSIVLAVIIGITQGMQPIVGFNYGAKQYDRVREVYKLAIKCELAITLVAFAVFQIFPQ
QVLSIF-----GSDE-VDQTLYFDFAVK--FMRTFLMLLPLTGVQMISSNFFAAIGKPLK
GAVLSLTRQVLFLIPL----VLILSYV--------FGLTGI----MAAAPISDLTAFAL-
-VMVFIVREMN------------------------------NMKKQ--SEIST-------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_011837.1|c2|1816155-1817537|-|YP_002472068.1|hypothetical_protein
------------------------------------------------------------
----------------------------------MTELENFILEGNIKTLLFKFSLPAIS
VFLANVLYNLIDAIFIG-NQANGSLG-I-AALSIVFPIQQIILALSQMIGVGIASITSRS
LGAG-NKLRAEKAVGTALTSSVLLGILIMVIGLAFIRPILYIFGS---SE--TILPYAVT
FFRITLYCSVFFVFSI-VSNSIIQSEGHANIAMISMIIGPVINIPLDYILVTRLK-----
YGIKGAAIATDISQIICFIFLLVYICF-------NSKI--------LGV-KVKNLVIN--
-I--KLLKEAISLGVSTFMTQLAYG---ILSIVLNNSLRIY-----GGSDLYLSAIGIYN
RIFGFITVPMYGIRQALQPIIGFNYGAKKFNRVKQSLKLGILTSVVISLGFLVIIISFTN
KIAGVF-----TSDN-E----LIALTVP--ILRVILLMSPLVGVQVIAASFFQYIGKPKP
ALFLSIMKQFLFLIPL----MLVIPIF--------FKVTGV----FVSVPLSDFFTAMI-
-SLIFIYREIK------------------------------KMNEL--NVIQGKNKNAHV
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACXX01000020.1|c1|61573-62988|+|ZP_05496138.1|multi_antimicrobial_extrusion_protein_MatE
------------------------------------------------------------
--------------------------MNENLNEQNDRQKQFILSGNMWKIMVNLSWPAIV
AMVLYGLNSVIDAIFVG--HFIGETA-M-AGVSVAYPLSQISVALGSLVGVGAGSVLSIA
LGAQ-DKKTQSRLFGNINLISLVVTVFYIIIGLVFSTELIKIMGG---TG--EALALGDR
YFRVTVIGSFFWIYGL-AGNMVVRAEGKMKTAAVMMGAGLVVNVIANYIFIVILG-F---
-GVEGSAWGANIGMFVYTLVGWIYFGK---G---FATF------K-SK---VFAVHWD--
-K--KIGTSIIRLGMSSLIMSIMTL---VQAVFVFNALSKY------GTTADIAFYGVVY
RVFTFLLTPIFGLMRALQPIIGINYGAKQHGRVIRSYKVFAYASMLLTLPFWIISMLFPE
SILKLM-----LKSP-V----FTSGEIN--NFRIYMAILPLLSVIFMAMTLFPSIDKGKP
AAIIGIARQFVFYVPV----MLFLPKA--------IGVNGI----YYG----SFAIDAV-
-IVLWTMLMVK------------------------------KEFSR--LRQIDSNDDKNS
FTFLKAKDI---------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABDT01000107.2|c1|57324-58694|-|ZP_02951175.1|mate_efflux_family_protein
------------------------------------------------------------
----------------------------------MKDMREDLLTKEPIALMIKLCVPAVL
GMLVIGLYSFVDAIYAG--QMIGTNA-M-GAVSVAYPFTLINSGISTLIGVGSASVLSRA
IGKK-DIDIINKIMGNLLMIIFILSVIVTVIGVVFAREVLLISGA---NG--EILDLAVR
YMRIVFIGSFFINFAQ-SANMIMRAEGRMKKAMIFMGIGAITNIILAPMMIILFN-----
HQVEGAAIATVLSQIIQAVITMVYFIK---E---SENV------------RFHGLKIE--
-F--DLLPEIFSIGFSAMLMQVMMF---IQQVVIYKMASIY------GGDSEIILIGAAL
RVLAFSFIPLWGMGQGLQPIVGTNYGAKQYDRVKKSINVFVVGATILALCFWIPIQIFPK
EILSLF-----IKDG-S----IVCGGIN--NFRLMYIIFPILGFWIMSVTAFQSIGKGKN
ASVLVISRQIALVVPL----IIILPML--------MGIEGV----WAAVPI-TDGIVFI-
-LTFIMMAVEY------------------------------KRIEK--IKNNEVLIFSEK
V-----------------------------------------------------------
------------------------------------------------------------
---------
>NC_011837.1|c1|1581530-1582891|+|YP_002471876.1|hypothetical_protein
------------------------------------------------------------
-----------------------------MIKMTDKRQE--LLTKSPVKLMFELSIPAII
GMVVIGLYTFMDGVYAG--QMVGENA-M-AAISVAYPITFINSGISTLIGVGLASVLSRA
IGKR-DKETIDKIMPNLTGLVLGISVLITILGVTFAREVLMLTGA---KG--EILELATN
YLRIIFCGSIFVNFTQ-SSNMIMRGEGLMKKAMMIMGFGAILNIILVPIMIKLLPDR---
-GVEGAAIATIISQTIQAFVTLYYFLKKSKN---VK---------------LNGIKIN--
-I--ELSKEVFSIGISAMLMQVLTM---VQQMLLFRMAFKY------GGDTNGIIMSASL
RLQAFTFIPLWGMSQGLQPIIGTNFGAKNFDRVKKSTNLFLMGSTVVALIFWIPMELFPQ
TFLGLF-----IKDN-A----IVVQGIS--KFRIFYSVFILYGMMIMLMTFFQAIGNGKK
AGQLVMFRQVILFIPL----ILLLPKI--------LGEPAV----WYTQPM-VDFLVIL-
-LGFVFLNTEY------------------------------KKLKG--NLMSVS------
------------------------------------------------------------
------------------------------------------------------------
---------
>NC_009706.1|c1|1581665-1583017|+|YP_001394908.1|efflux_pump
------------------------------------------------------------
----------------------------------MTDKRQELLTKSPVKLMFELSIPAII
GMVVIGLYTFMDGVYAG--QMVGENA-M-AAISVAYPITFINSGISTLIGVGLASVLSRA
IGKR-DKETIDKIMPNLTGLVLGISVLITILGVTFAREVLMLTGA---KG--EILELATN
YLRIIFCGSIFVNFTQ-SSNMIMRGEGLMKKAMMIMGFGAILNIILVPIMIKLL----PD
RGVEGAAIATIISQTIQAFVTLYYFLK---K---SKNV------------KLNGIKIN--
-I--ELSKEVFSIGISAMLMQVLTM---VQQMLLFRMAFKY------GGDTNGIIMSASL
RLQAFTFIPLWGMSQGLQPIIGTNFGAKNFDRVKKSTNLFLMGSTVVALIFWIPMELFPQ
TFLGLF-----IKDN-A----IVVQGIS--KFRIFYSVFILYGMMIMLMTFFQAIGNGKK
AGQLVMFRQVILFIPL----ILLLPKI--------LGEPAV----WYTQPM-VDFLVIL-
-LGFVFLNTEY------------------------------KKLKG--NLMSVS------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACGC01000054.1|c1|1202-2560|-|ZP_03930533.1|MOP/MATE_family_multidrug-resistance_efflux
------------------------------------------------------------
----------------------------MRGLKMKQNMKEQLLTKKPLSLMFQLSIPAVI
GMVVIGLYPLMDGIFAG--QIIGENA-M-AACSIAMPLTFFNNGIATLIGIGSASILSRA
MGKG-DKDTIDKLMGNLIYWVIFFSTIITIGGILLGPYFLDLIGA---TG--EIKALGIR
YLRIIFLGSIFVNFTQ-SANMVMRGEGLMKRAMSIMGLGAFINIVLDPILMKAMGDY---
-AIEGAAIATVTAQIIQAVITLYYFKN---K---SENV------------KIGKIKKE--
-K--DISKEMFGVGVSAMIMQVFFM---VQQTLLYRQAFRY------GGDPNAILMSATL
RFYGFSFIPIWGMSQGLQPIIGTNFGAKQYDRVKETMKIFSIGGTVLAAIFWLPAQVFSK
QLLGLF-----KVSQ-D----IISSGVN--NFRIFYSVFILYGIMIMTITFFQAIGDGKK
AGMIVMLRQLILLVPA----LLIFPRV--------FGVGAV----WWAEPVVDFTMIMV-
-GLAMQAKAIS------------------------------NMNLN--N-----------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACGC01000006.1|c1|16655-17995|+|ZP_03929435.1|MOP/MATE_family_multidrug-resistance_efflux
------------------------------------------------------------
-------------------------------------MKEQLLSKRPIDLLFQLSIPAVI
GMIVIGLYPLMDGIFAG--NIIGQTA-M-TACGVAMPLTFFNSGVSTLIGVGSASVLSRA
IGKS-DQKTVDKIMGNLIFWVILFSSIITIGGILLAPHFLDMVGA---SG--EIKEYGIR
YLRVIFIGSLFVNFTQ-SANMVMRGEGLMKKAMLIMGLGAFLNIILDPILMKLMGKY---
-AIEGAALATITAQFVQAAITLHYFKN---K---SKVV------------KINKIKSE--
-P--EVKKEMFAVGTSAMMMQVLFM---IQQTMLYKMSFKY------GGDTNAILMAATL
RIYAFSFIPLWGMSQGLQPVVGTNFGAKRYDRVKDAMKVFSIGGLVLAAIFWLPVLLFSK
NILSLF-----GVEE-S----IITQGVG--NFRLFYSIFILYGVMVMSITFFQAIGNAKK
AGIIVMLRQLFLFVPA----MIILPMT--------FGVKAV----WFAEPL-VDLIMIL-
-AGIAMMIGEL------------------------------NRMPS--EIKKI-------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABYO01000220.1|c1|30142-30993|+|ZP_03916387.1|MOP/MATE_family_multidrug-resistance_efflux
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MGLGAFLNIILDSILMKLMGKY---
-AIEGAALATITAQLVQAIITLLYFKY---K---SKAV------------KINKIQSD--
-Q--EIKKEMFGVGSSAMMMQILLM---IHQTILYKMAFKY------GGDPNGILMAATL
RIYAFSFIPLWGMSQGLQPVVGTNFGAKKYDRVKEAMKIFSIGGLVLALIFWIPALAFSK
NILSLF-----GVEE-S----IITQGIG--NFRLFYSIFILYGVMVMTITFFQSIGSAKK
AGIIVMLRQLFLFVPA----MIILPMI--------FGVKAV----WFAEPL-VDLIMII-
-AGVVMMFEEL------------------------------NRMDK--IGLKNSSNE---
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACXU01000005.1|c1|291992-293356|+|ZP_05472192.1|MATE_efflux_family_protein
------------------------------------------------------------
---------------------------------MKQDMKEQLLTKRPIDLLFQLSIPAVI
GMIVIGLYPLMDGIFAG--NIIGQTA-M-TACGVAMPLTFFNSGVSTLIGVGSASVLSRA
IGKG-DKKTVDKIMGNLIFWVILFSSIITIGGILLAPHFLDMVGA---SG--EIKEYGIR
YLRVIFIGSLFVNFTQ-SANMVMRGEGLMKKAMLIMGLGAFLNIILDPILMKLMGKY---
-SIEGAALATITAQFVQAIITLHYFKY---K---SKAV------------KINKIKPD--
-Q--EIKKEMFGVGSSAMMMQILFM---IQQTMLYKMSFKY------GGDTNAILMAATL
RIYAFSFIPLWGMSQGLQPVVGTNFGAKKYDRVKEAMKVFSIGGLVLASIFWIPALAFSK
NILSLF-----GVEE-S----IITQGIG--NFRLFYSIFILYGVMVMTITFFQSIGNAKK
AGIIVMLRQLFLFVPA----MIILPMI--------FGVKAV----WFAEPL-VDLIMII-
-AGVVMMFGEL------------------------------NRMDK--ISLKNSSNE---
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABAX03000014.1|c1|138628-140001|-|ZP_02419664.1|hypothetical_protein
------------------------------------------------------------
-------------------------------MLNKNDTRSMLLHDSPQSLVLKLSVPAII
GMVVVGLYNFMDGVYVG--QMVGDNA-M-AAVSVSYPFTLANSGISTLIGIGSASILSRA
IGKR-DQSTIDKIMGNLIAMNLIFSLIIMAIGMIFTKQILMLSGA---SG--EILELALR
YLRIIFAGSLFVNFAQ-SSNMIMRGEGLLKQAMLFSAGSAIMNIILDPIFILLLKPY--G
MGIDGVAYATVASQVAYAMASLWYFKR---R---SKTV------------RINAIRIE--
-R--TLFSEIIGVGFSAMLMQVMML---VQQTALYNLAAQH------GGDTWQIILGATY
RVVSFAFIPLWGLSQGYQPAVGTNYGAKQYDRVKHITKVFAITATLLALIFYLPIMLVPN
TILSMF-----ITTP-S----VVELGVG--DFRLFFLSYILLGVWIVVLTLMQSLGRATK
ASVLVILRQIAIYIPA----AIIMPYIA-G-----FGVHGV----FAAPFI-TDVIVFI-
-VAVGMMINEF------------------------------RRMDA--LKASGK------
------------------------------------------------------------
------------------------------------------------------------
---------
>FP929055.1|c2|1289885-1291258|+|CBL25885.1|putative_efflux_protein,_MATE_family
------------------------------------------------------------
-------------------------------MEKAIDTRTKLLTKNPFSLMLELSIPAIL
GMVVVGLYNMMDSIFIG--QMVGAAQ-M-GAVSVSYPFTLINAGSAAMLGVGSASVLSRA
IGKK-DEGTIKKIMGNLVAMVILLSVIYTIIGMVFTRQLLSLAGA---SD--NILNYAEK
YLRIVFAGSLFVNFFQ-SANMVIRGEGQLKKAMSIIASGAILNIILDPIFITILKPY--G
MGIEAAAFATILSQFVQAVITLWYFRK---K---SPNV------K------IGRIRID--
-G--ELLPQVLSVGVSALLMQILTL---VQQTVIYRVAANY------GGETSQILLGAAL
RFWNFSFVPLWGISQGFQPAAGTNYGAKDYDRVKTLTKVFVIAATVLSLIFYIPAELFPA
KVLSMF-----ITTP-G----VAASGAT--NFRIMFSTYVLQGSFMIAVTLFQSLGKANK
ATWLVLFRQIILFIPL----CVLLPMIG-G-----MGIRGV----WLAIAL-TDAILVV-
-ITISMMISEF------------------------------RKMPS--TVMAKR------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABFY02000013.1|c1|21512-22933|+|ZP_02431052.1|hypothetical_protein
------------------------------------------------------------
--------------------------------MQETTKDERLGSERLGKLMVSLAVPAVA
AQLINVLYNIVDRIYIGHIQGYGDMA-L-TGVGVTFPIIMLIAAFSAFAGMGGAPLASIQ
LGKH-DYDRAELILGNSAGLLVIFSVVLTIGFSIFKTPVLYAFGA---SE--TTIQYAES
YIGIYLLGTIFVQFAV-GLNTFISGQGEARIAMLSVLIGAIINICLDPVFIFVFG-M---
-GVKGAALATIISQAVSAAWVIKFLTS---K---KSVI------R-LK---AKNMRLK--
-G--DVVKHIGGLGISPFIMQSTES---LVNITLNSGLQKY------GGDLYVGTMSIMT
SIMQLIVIPIQGITQGVQPIISYNYGAGNKSRVKGAIIRLIAVCFLATIVLAGIAVFAPG
VYAEIF-----TNND-Q----LVKLTCQ--VMPIYFFGITIFGIQSACQSTFLALGQAKV
SLFIALLRKVILLIPL----AIILPKF--------MGVIGI----YRAEPV-ADIISVL-
-ATSVLFVITV------------------------------KKVLR--NMGNNDMISADQ
GEDGGNNERLYN------------------------------------------------
------------------------------------------------------------
---------
>NZ_ACDG01000116.1|c1|59768-61024|+|ZP_05628194.1|mate_efflux_family_protein
------------------------------------------------------------
------------------------------------------------------------
---MIALYVIVDSIFVG--RGVGKEA-L-AALNIAYPIITISSAISLMIGMGASTLISLY
HGKK-HLEEL--CLSYIHCLNFLFYVVLVFLVFFCSKQVLWVLGG---ET--SLEAMIRG
YLYPCTVGMIFLMIST-GWNAAVRNLGAPKYAFFSMLAGALCNVFFDWIFIFPMD-----
LGIQGAAIATSMGQILSFLLLLFFFRK-------KRIF--------IP---FFPRKIS--
-W--SLLKRLFSIGFSSFIMEFAAA---IVLVLFNIQFMRY------GGEISVSAFCIVA
STFYFFRMLFTGLGQGLQPIVSFFFGKKEREKGKEVYRKAKSLALGISVLCFAFVFFQKE
SIMSFY-----HSDR-N----FILFAAR--GLLLYCTSIFFVAFNLLSISYYQAVGNGRL
ANIFSFGRSFLFLLPF----LYLLPAV--------WGVTGM----WLVLTFTEASTSIS-
-IFCYQNYRKK------------------------------KKFLD--IGRRV-------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_AAML04000010.1|c1|401263-402207|-|ZP_01804170.1|hypothetical_protein
------------------------------------------------------------
----------------------------------MDTKISINENMSLGKRFFKYLAPSVV
AMWVFSLYTMVDGIFVS--KGVGELA-L-AAVNISMPFINFIFAVSLLFSTGASTIIAIY
LGKK-DIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGA---TE--STIGMVKD
YLGIIIFFNGFFIVSY-SLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFG-W---
-GVKGAGIATVLSQVFSTIFFLIHFLR---K---NSTL------N-FS---KFRIDFK--
-----TLRKIVFIGFPDSTTELSCG---IVVLLFNLSLTKY------IGENALIYYSVIN
YINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKN-------------------------
-----Y------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABHD02000014.1|c1|109125-110480|-|ZP_05329416.1|putative_drug/sodium_antiporter
------------------------------------------------------------
----------------------------------MDTKISINENMSLGKRFFKYLAPSVV
AMWVFSLYTMVDGIFVS--KGVGELA-L-AAVNISMPFINFIFAVSLLFSTGASTIIAIY
LGKK-DIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGA---TE--STIGMVKD
YLGIIIFFNGFFIVSY-SLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFG-W---
-GVKGAGIATGLSQVFSTIFFLIHFLR---K---NSTL------N-FS---KFRIDFK--
-----TLRKIVFIGFPDSTTELSCG---IVVLLFNLSLTKY------IGENALIYYSVIN
YINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFVICMAFSG
PIVSLF----IHPEETM----LFNEGVR--VFKIFSISFLLVGINVIISGFFVSVEKPSI
STVISLGRGLVIVVLS----LISMILI--------FGGQGI----WMTTIV-SEFICLI-
-LSLAFLKKNF------------------------------STLDS--NLNKVA------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABKJ02000016.1|c1|121376-122731|-|ZP_05350555.1|putative_drug/sodium_antiporter
------------------------------------------------------------
----------------------------------MDTKISINENMSLGKRFFKYLAPSVV
AMWVFSLYTMVDGIFVS--KGVGELA-L-AAVNISMPFINFIFAVSLLFSTGASTIIAIY
LGKK-DIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGA---TE--STIGMVKD
YLGIIIFFNGFFIVSY-SLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFG-W---
-GVKGAGIATGLSQVFSTIFFLIHFLR---K---NSTL------N-FS---KFRIDFK--
-----TLRKIVFIGFPDSTTELSCG---IVVLLFNLSLTKY------IGENALIYYSVIN
YINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICMAFSG
PIVSLF----IHPEETM----LFNEGVR--VFKIFSISFLLVGINVIISGFFVSVEKPSI
STVISLGRGLVIVVLS----LISMILI--------FGGQGI----WMTTIV-SEFICLI-
-LSLVFLKKNF------------------------------STLDS--NLNKVA------
------------------------------------------------------------
------------------------------------------------------------
---------
>NZ_ABFD02000008.1|c1|403675-405030|-|ZP_05271440.1|putative_drug/sodium_antiporter
------------------------------------------------------------
----------------------------------MDTKISINENMSLGKRFFKYLAPSVV
AMWVFSLYTMVDGIFVS--KGVGELA-L-AAVNISMPFINFIFAVSLLFSTGASTIIAIY
LGKK-DIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGA---TE--STIGMVKD
YLGIIIFFNGFFIVSY-SLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFG-W---
-GVKGAGIATVLSQVFSTIFFLIHFLR---K---NSTL------------NFSKFRID--
-F--KTLRKIVFIGFPDSTTELSCG---IVVLLFNLSLTKY------IGENALIYYSVIN
YINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICMAFSG
PIVSLF----IHPEETM----LFNEGVR--VFKIFSISFLLVGINVIISGFFVSVEKPSI
STVISLGRGLVIVVLS----LISMILI--------FGGQGI----WMTTIV-SEFICLI-
-LSLVFLKKNF------------------------------STLDS--NLNKVA------
------------------------------------------------------------
------------------------------------------------------------
---------
