>NC_013132.1|c11|6801520-6803364|-|YP_003124958.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MSMPAVNLK-------------------------------DEQVIAAALLDLAEKL
LPAIQPDTIAAD--LH--------------------------------------------
-----------NGAPV--------------------------------------------
---------------------------DLFNGKAGIIVFYL-------------RLAEYD
PGYLPVCTAAADVLLY--------------HPAISE-QAFFTLYTGATSLVYLCIQLYEA
TGDQR------YLERGLALVAHYQEGILQKVVQDD-FISGHAGNLLVLTQLHAYTK----
--------DDSLRVLIRQLADKLVAH-------------------------------ARI
AAQGLRWGHL-----------------------KR-----------------SYDCLTGL
SHGAAGIAHAL-------------LQVAVYFED-EGLRYLAMQSWAY----EMKYYDPVF
KN---------------W----------------------------LDLRLTSTHLQETD
IMG-----------------WQIADFRRYISDV-NAWAHGAAGIGLSRMYA---------
-----------------------WGISGEAH--FAAESEWALTRCLQDADT---------
------------------------LMR--GDFTLCSGYGGIGMFLMEAGAVFDRPV-LRQ
-------TA--QRIA----MAAI--RYFEAHGTYN--SYIKDAQDDPGLF--SGLAGVG-
YLL----VSVLLP-------YKENTVMA-PLISRNR----KDVPLY--------------
---------------------------EK--GEVKRALFSRYYEKS---LQQ--------
-----------------------------------------YPAALIANDMHELEQLLEK
----------EMGD------QDCFRYEKS-----LADVWR-------------------S
HSGWLCYQQRNRLLEKR---NSYLLQENDRVLLQ--TVF-----VPVPELMV-----CAT
DHAWHGE----------AV----TNQQESTGYYYVH-IAHVQGVSTFPVN--QFTAMLLK
AFEGQLPLLQLIT---------------------DIIYPQVD--VGMAALQ-EAVLS---
----------QVRVFLRQCMITQK-----------------------------------
>NC_013730.1|c6|5096939-5098924|+|YP_003389012.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MVFKKV---------------------NTLLQPEDASIFLSE
AISIGTWTIEQA-----------KRSEQGI-----F----------------WTMYYND-
------------------------------------------------------------
-----------------DDLISEAA--TTHLYSGTAGVIHFL------------MELYLV
TNDPNLEEYIHGGLRWLIH--------------------------------------HSK
SSGLD-SYSMFTGRLS--VALCFLRAASQFNNPNY--LNFAYSSLESVESFLTSST----
--NDLINGISGCLLGLVHFYHHTKDESILPLVFK--------------------------
-----------FIDRLL----------------QNCRFL-RDSVYWD-----LTKDHTQP
LCGFSHGLAGIGFCLLEVGHYFNLPFLTDLAQK-------TYQAENYHFQPHKLNWPDFR
KG---SYSKKD----------------ENEFRRSLI-NKDLYPFIKEKFMFAWCHGAPGI
GLS---------RLRA----HQITGNKTWLNDLEMAITSTSHDLDNTGINSYC-------
--------LCHGGAGNADLLIEAFLYTNKQD--YFEAALKVGKKALQQKEQ---------
------LGY--------YRPGSLTDKP---DAALFTGTSGVGLFYLRLL-----------
-------FP-------------------------------------------SSIHSVL-
YPV-----------------LPKPEMQFHLNNNLWS----EKKASF--------------
--NLVKASFSNATNYLNY----------KGINEIGLPIESILGINF--------------
-------------------------------------LSKTTLKHHLIWIRLKLFKKDYK
----------KYVS----LLKLDIKLFRS-RLSFESNNVL-----------------SYT
KYRY-RLEQSQYLLSKV-----------------------------ENHINT-----FFK
LTADASL----------------VQNLTELNEIQYF-LVYYNPYINSTYSVIKISSLSNA
ILTYLLTSNTLTS------TVRYVDELLE-----DNHDISLLQISELVRNQLWEFIKMGL
LEESST----VNSQ---------------------------------------------
>NZ_AAYW02000017.1|c1|27164-28492|-|ZP_02075426.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MADYLTYA---------------------------------------------KE
TMNF----------IN-------SRKKQGP------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------EGIYWSLQDAAEGRSIYYDEICMYAGASGIIVFLLGLYQTTN----
--------------DVSYLQEAEEAATYIRYRFDHDRDL-----KRNFSKYAFSSGWSGA
GFAMIQLYKATGNEK-------------------------------------YKTFVADI
IESAKADA-----------------KPGKNGKG-----------------YSWTSFPGIV
GD-------------------------------------------AGTVLFF--------
LYA---------------------------------------------------------
-----------------------AKTFGRGD--WTAFAAKAGENFLEQRHD--------A
GNETCWYPG--------VDPVYFGAKEDYIDPNFPMGTGGIGFVLLNLYEASGNQK-FLD
-------AT--KGIA----------DFMIAQAVK------------------MKAGSLIP
HGL-----------------PDRKDLFY--------------------------------
------------------------------------------------------------
-------------------------------------LGYCHGPAGTNRFFYKLYEMTGE
----D-----RYKRYIDMLTQGVIDTGAP---------------------------EVRT
EGYW--------------------------------------------------------
----------------NTY----NICCGTAGLLNMY-LGLWA---AFGDE--TYLKQAKR
CGKVITDGATITD-GTEGRECAWRFALDRVAPDVLSTPIGLF--DGAAGIG-AVLLQ---
LASAEKGQFHATRMLDDPFPEKNKL----------------------------------
>NZ_ABWN01000037.1|c1|34328-35680|-|ZP_05792932.1|conserved_hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MADR
LINVFRKSKLND----------------------------------------YLESAEK-
------------------------------------------------------------
----------------------TAG-----------------------------------
---------------WIKK--------------------YEIADEKGKHWK---------
------------------------ISGTE----------GKDPDAVESSFLTDTSL----
--------------------------------------------YGGAAGIGY-------
------------------------------------------------------------
---------------------------------------------FYLQLYELTGAEKYL
EE-------------------------AEDAAEYLINTYEKEDVVN---PGIYNGLSGQG
IFT-----------------------------------------------LLL-------
-----------------------YDKTGDER--YLQFAKTLAEDSYTQSVK--------D
EKGIHW-----------------------NGWYDYMGDGGVIAYWMYLAEKTKDGH-YLK
-------YA--KEAL----------DAILSLKKQF---------SGDSIY----------
FEL-----------------FDPSVYFT--------------------------------
--GVPSG--GVV------------------------------------------------
-------------------------------------PNFAHGTAGIVYLLTKYYEVTKD
----E-----EYLK----YAVQGYNFLKEIANCTEKASIV-----PYLYFKGGENKYDVS
YLGF-CHGPVGDGITVR---ELYLATG-------DKEYLDFYNRLTEALIEA-----GVP
YKHSAGY---------WNN----CICCGTSGILLHF-IDAAK---LTGNE--KYKDYADK
IAYKLLNDAYTDSEGNRWYDAWTRVKPWD-----VDAHLGLF--VGAAGNA-SALLS---
YYSDKTGKKTTPVFEYQEAFA--------------------------------------
>NZ_AAYW02000016.1|c1|127340-128746|+|ZP_02075313.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MAKLIT--------------------------------------
------------------------------------------------------PEIFQK
NTAEDYLKAAIDTAEWIDT----------LAIKTEYGRIWQALPEGQDGYRE-----DVP
LFTPK-SMYDGSAGIGIFFIRLY-------------EATGDTRWLTEAEEAAAHII----
--------ATKVGVEWYQTTLHSEVKGIIPVPGW-----------------------AAG
PYNGPVGEAY-FLEDLY-----------------------QVTGKQE-----YRDYVLYV
ADVLLEAA-----VTDERGLHWSDQEDITADGG-------------FIVFLDILYRKTGI
RK----------------------------------------------------------
------------------------------------------------------------
---------------------------------YLDTACAAADRIAQDALP-------AP
NGGKFWKLL---------DLSMIDFEKDTTFPNWSHGTTGTAWMFAALYQDTKKEE-YLE
----------------------------------------------------LAKEGLT-
YAM---------------------------------------------------------
--NIAVGDETGRLIPYQD----HPVTGPTYDKYY--------------------------
-------------------------------------LSTCHGPVGSTLAFRELYEITGE
----E-----IYRNWTIELSRGIVRAGAP---------------------------EKHS
WGFWNCQ-----------------------------------------------------
-----------------------CQCCGTAGILEHF-AAMYE---YTGEK--EFYDYMIR
TADVMLSDSDHRTPGLRTWYDSWWRTIPTR----VVSYPGLY--VGVAGCA-SSLLRTYA
ALTGKK----LTNLYEYHFFEKF------------------------------------
>NC_012560.1|c1|923751-925583|+|YP_002798177.1|lantibiotic_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MFSTKSKARHLG----------
-----------GGAPIKRETEVIYATAINGGD---------------CVTAANYNGKHRV
LVEVIINDILERT---CFDKRKDI---------------------HRKLVTALAGYAANK
IDLYMRHVLEFE-----------LGSLSEV-----L----------------ENVNLDYI
MDSDELYIAILKKYPGLEPLVDHLGSSLIENFTLIIKSFEDAEFELVSNG----Y-----
----------LSSVNNITNIFLLSD--ESHDANKNIVLFYDS---YK-------PAFALK
LRNITLEKQTNDFISGFLR----------ENMGFEDWNFPNYLDHGEVGWVSWRP--RQD
LNSEK-QITESYFRSGVLASISCALGITDLNHENI-IIHAGSPVIVDLETTLHHCV----
---------------EGGGSTNALRTGLFPSFLKLDRNGSP---TEESCGIG-----NIF
PEYRLKSKNN----EVC-----------------------FDNKIAS-----PIDYIEYI
KQGLRLGF-AK--VIQYKEKFV---DHIVRIEN-FRTRFIFKATYSYATIIESSMHPALL
KS---AVIREE-YITQCF------ESENKYVEGDEAKWGEIKACYLGDVPRFITTANSLI
LDS---YYQQTPTTLR----HICTGVSRTLQYL-QDLNDKIVDEEIFYIEKSY-------
--------AEAYRVMSVNAKSY-----------EIENYQKLINCANEFALN--------N
KMPVFFMPR--------------------NDYCLELKSCGLDIF----------------
----------------------------------------------------SGIGGIV-
YLA---------------------------------------------------------
-------------------------------AIKKLPVESTISDRI--------------
----------------------------------------------IANYIERLNSTQRN
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>NC_002935.2|c2|729107-732040|+|NP_939126.1|putative_lantibiotic_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
---------------------------MLVGSIRKFFPEITDDLFQELLT----------
---------SAAYEHGVASLQGEIEKFTQKNS------------ETDEEVLADNLAELYR
FFEREPIPFLDSTWALSDLQISSI--------RDVIDAFPHRIDCDAVIKSFVSANC-SA
LQRLLLRCQL-------------EFVEKEI----------SSNGP--ELT--YEESSQAL
FRS---LAQFKERYPIAWYLANRKCERSLRYLSEILDHLKEDWSRLSRFG----L-----
-----------TEDSQVSNITFELG--DTH-DGKSVAVVTLD---DG-------QQIFHK
PRPLDVEESCSRFAEQLGR-----------MFGFTCPFVGKVITRGSYGWAEHVPHVEES
RFDNP-------RAAAEFALLLKLLSFTDVHYENVRFSADGIPILVDAETALTSGL----
-----CRRDSEGIPIHAALSETVTSTGFFPSPLVIPKKRGET--FVDVGVLGRRDK-NLI
TERQLVLKNP-FTNKMH-LVYEDVAKHMS----DNASSFRF-----------SSDYVRSL
TERYRELT-KA--VVDKKASIS--NLLRECFSK-SCFRVVVQDTIKYVNAIQLATNQQCL
SS---PSLYVGALLRFAI---------GRFDSDRLLLRNELASLISGDIPRYVVSATSSD
LEG---SVQT--VKKN---YFIESPIENAIGCV-QKMDSKTIELDCWLIEISF-------
--------ASYYDESSNATQFKYSDSLFNVSHNIEVSLNEALTSLLNGYVY----G--SG
SAPATWIGA---RLSN-QAHQYWYVDE--VSMDLYAGSSGLALPLVLSGPAGLSCR-GRK
-------EA--HDYF----DGLV--TKLESLDTTQ------LATLNTGAL--SGAHSVL-
WSL----HCHYSA-------AGDNGGLE-RLKSLAN----KMISCASHDGF---------
--DFTGGTIGLSVLAKAL-----GVFESTKIEDDYLNALDSLAEST--------------
----------------SRGCSWL--------------SGYAHGHAGALASAAMLCDHISN
----RDRLESSVSR----LFSQFLSFRES-----ESRLWP------------IGFEQTGI
GRGW-CSGTPGVLLALA-------QFH---------ESELGKCYELAPTIEF-----LTD
VVKKETF-------G-GNP----TLCHGDVGNLWIL-QKVGE---LIGDH--ALVTRSRE
AGLFWLQNVLPS----------FLRSLSR-----FSISHSFF--AGIAGTALYGEYL---
LSSEEV----VRCPLWLE-----------------------------------------
>NZ_ACPD01000003.1|c1|45934-48075|-|ZP_04803872.1|conserved_hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MLSNNDSAKKECIKSIPKEK
HATHGISKMVAR-----------------------L----------------YKSLPDI-
VKDKKEFITYLVEYFYENILDQDKIVEYFMFILRAIKLTEKNLFDIKSKI----L-----
---------NTDEHIEIVKIDSYLL--------DGSAIIWFS---DG-------KSIVFK
MRALEDIERFNYIINWTNS---------KLPDKYKL-STSCLLNYKRYGFIENIA-----
-NEIPQDLEEYYFNSGQLLALLYMMDCNKVEKKDI-ISLRNCPSILNCTNLFIVQE----
--EIFNQEISSTDIAKKILDYSVYNIEFL---------------SEDMSCL---------
----------------------------------------------------AKNYINLI
KSGYKYRY-NI--ISSNKSQLI--------------------------KIINELFKGDHL
------------ILSHMI------------------------------------------
------------------------------PKI-YNFTENDLKQQLYFLDVRF-------
------VQFKYQDSNFKFLVGDTYDNLNKEE--LKEIAIKLGDYIIQKSII--GVE--NS
LTTRSWITD-------VKLGNKLELSH--KCNSISYGTCGIAIFLLYLGVVTQKAY-FIA
-------AS--IESM----RKVIYAMNKKSIENHT-----------------LRESAEVT
YTL----LKIYMI--------TKDEFIKSSVIKISS----LAFSILSNSTDK--------
--LELEDMEAFTIILLAI----YKEKLSDFNINRVFKIADLSYNKV--------------
------------------LGFWKNEVCK---------NSLNYDVNGVVVIFSILLYIKKN
----A-----VIEH----EIQQLLKIERS----------------------IGSKKQCRK
KETY-----KKVLISRS---ILKEYGY---------NDG-----LIVQELNE-----TIK
YIIEKEF---------GNG----TYYNRDIENIELV-RYAAS---SLEDD--VLINSCNS
NLNRLVKEDLIEN---------IKKQIKF-----EDRPLSFK--YGTIGQG-YRLIR---
IYNEDI----VPQILFI------------------------------------------
>NC_003030.1|c1|89767-91827|+|NP_346727.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLGRRKNGIAME--LK-------SIETVGD----------------------FISLSGN-
-------------------------SRRLTSILKVKRLIRENYSIIRSNL----L-----
---------NTEDKVAIKEIKYYEK--EER------AIVTFT---DN-------EKVVFQ
SYISKDEEIINKFIRWINQ---------KVDKEHSL-YVKKILYAEGCSFSEYIK--PIN
SIGKR-EIFDYYFKSGELLLILYVLRCSKIKSKNI-IDMEDCPILDEVKDAFYSTN----
--DVPSFNFSANEVAEKLVKYSVYNIEFLP------------------------------
---------------------------------ESKKSI-------------TEEEIYHI
KCGFEYIY-NM--IMYNKLELI------------EVMKVIFK------------------
--------------------------------EDIL------------------------
------------------------KLSAVITNI-YGLNEEDLKRQLYFIDIRF-------
------IGVKIARRKVNFCISERKETIDKNY--FISIANDLGEHMIKRGII--GVK--DF
VTSRTWIST-----TRDGNNQGYSLSP--LSSDLMDGSSGVALFFAYLGLVTGKDY-YKA
-------IA--IEAI----QDSI--NHINNLNNND--------DINIGAF--KGISGEI-
YAM----WKIYSV--------TRSNYLEASIENGIR----ALYILVQKSKDI--------
--DITNGLCGVSCVLVSI----YKDKDSNKFNDIIMNLIRICMEKI--------------
--------TGNMSSKQMA-------------------LNDVYLNDAIILTLAKLLELTGE
----R-----SLVK----KIKELFSIQRM--------------------------KYKDI
FARW-DRRILITLMGRV---TLKKINF---------QDE-----SIDREIQQ-----ISK
YIINNGF---------GNS----FSCCDDMGIIEVL-KHTAA---ILSDE--KLNSSCIK
TFNELVKKKIKPT---------INKEITY-----ANENISLM--NGVVGLA-YSLIR---
ISSEKF----VPKILWLE-----------------------------------------
>NC_001949.1|c1|33357-36140|+|NP_047323.1|lacticin_481/lactococcin_biosynthesis_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MDPSIKKLVDSII-------------------EFYKKDIYL
AYKELEREIKNIDKTIYNTSNDEI---------------------LRIFKESLISIITDD
IYRLSIKTFIYE--FH-------KFRIDNG-----FPAVKDSESA-------FNYYIST-
-FDVKTIARWFEKFPMLESIISSSIKNDCTFMVDVCVNFILDLSECEKIN----L-----
----------ISEDSRLITISSSNS--DPHNGGTRVLFFRFH---NG-------DTILYK
PRSLTVDKLISNIFEEVFE----------FDATNSKNPIPKVLDRGTYGWQEFIE--KKS
ISSSE--IKQAYYNLGIFSSIFTVLGSTDIHDENL-IFKGTTPYFIDLETALSPRI----
--RYEGNEENLFYRMSSSLFTSIVGTTIIPAKLAVHSQ------EIMIGAINTPAK-QKT
KKDGFNIINF-GTDAVD-IAKQNIEVER-----IANPMRIKNNIVND-----PLPYQNIF
TRGFKEGI-KS--IILKKGSII---SILNNFNS--PIRYIMRPTAKYYLILDAAVFPENL
YS---EQTLNK-TLNYLK---PPKIVENSLISKQLF-LAEKRILSEGDIPSFYVLGKEKN
IRA---------QNFISEQIFEETAVDNAIQIL-ESISQDWVNFNERLIAEGF-------
---SYIREQSRGYLSSDFENSDIFKSSLTET--KKSGYTAMLKTIISMSVK----T--SE
NKKIGWLP---------GIYDDYPISYMSAAFCSFHDSGGIITLLEHHFGHCSPE--YNE
-------MK--RGLL----------ELGKMLKINN---------SNLSII--SGSESLE-
FLY----THREVE-------CLELEYILNNSAEIMG------------------------
--DVFLGKLGLYLILASY----LKTD-----LKIFQDFSIICQKNL--------------
--------EFKK-------------------------FGIAHGELGYLWTIFRIQNKLKN
----KN----ACLS----IYHEVLNIYKG---------------------------KRIE
SVGW-CNGLSGILMILS---EMSTVLE-----------------KNQDYLFK-----LAN
LSTKLNE-------ESVDL----SVCHGASGVLQTL-LFVYS---NTNDK--RYLSLANK
YWKKVLDNSIKYG---------FYNGERD-----KDYLLGYF--QGWSGFTDSALLL---
DKYNNNEQVWIPINLSSDIYQHNLNNCKEKNYEGDGCHKS-------------------
>NC_003265.1|c1|30186-32939|+|NP_478387.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MNKIKDVTNIITR
AIEEININMLENNNIQIKKITEDI---------------DDGDNINNLIEQCRQSLIEIN
VWKITYKTFVYE--FH-------EFRKKIN----------YPIST--NSSIAYNHYINN-
-ISAETLIHWFNKYPYLREIIEKIINNICEFSLKVCHDLITDWNILIEKN----L-----
----------INKGEKLQNITCLDS--DPHNNNKVGLCFDF----EK-------SKVLYK
PKSLKVDMLISEIFENILQ----------FEELNKIIPVATSIDRGDYGWQRFIN---RN
YLNKD-DLPKAFYNLGLCSSLFTALGATDLHDENI-IFNNEYPYFIDLETCLQPEI----
----KYINNSLVDTMLDNIKSSIASTSIIPSNIISYLQ------QILVGAINTPYP-QKT
NKRRFSLKNF-GTDAMD-IAKENVTVNHL----KSSIKL-TEGEASN-----PLPYQFDF
LEGFSKGY-KR--VLEKSDSIK---KLLNNHS--FTSRVIIRPTDQYYLVLDAIIYPENL
KS---EKNVDN-ILDYLK---PTKLVKDRKIALDLL-KEEKKAIKQGDIPFFYTYNSKHN
LKT---------QGYTTGKAFELTPVDNINVKL-NNLSNKRKLLNFQFIAEGF-------
-SYIKLKEAEYFNEDNILHFSPLFKNTLKKT--TINNPYPIIDLLLDLSIT---TN--SE
IKKTGWFNG--------MYGNMPSMYNSMTNFSLHD-TGGVIFLLEHIKD-------FRQ
-----------NPSL----------VKLDFLNSAK-----------------LGLQELQE
YFFNDKTSNYFSI-------ISGKSSID-FIFDYKN----EKSDNLEKAGFDCCFTKKGN
--DVFNGTPGLGLVLSSF-------------PLTSSDILFKILSTM--------------
--------VYDGKNHSK--------------------KGIAHGELGILWSKYRINKFLKR
------------KD----TCKKLFEEVKN---------------------------ITYS
LTGW-CCGNAGLLMVLA---EMCTELN-----------------VEKQFLKS-----IAK
KAIILS----------NNEPIDLSVCHGASGVLQSL-LFTYR---ATNDE--WYLSLANT
FWQKVLDLSKKNG---------FYTGEKN-----RDYILGYF--LGWSGFADSCLLL---
AQFNNKKKPWIPLNLSSSIYQENL-----------------------------------
>NZ_ACEB01000042.1|c1|48568-51405|+|ZP_03711708.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTLERAIADKLLARLWSVAGPVRD----------------IPPERFVSEVRN
RTADFLTQIPIEL---RRAASDAV--------------------SDCLGRIIAGNLSRAD
FAAAMHDQLLKIDEVG-------EWPQSEV----------VADAA--GGQ--WRNVVAQ-
-----IAGRWYNDLAVASKYRVRSNSALAIRLVMAHRHVGAAAARLEQRI----A-----
----------EELPDTPNRVVLGLG--DAHSRQQTVARVEFA---D--------RQLIYR
PHSMATDQVIADICRLVGA-----------------PEPPHAFDMGDHGWSEFLT--AGP
GVTDE---AEFYAAVGAWAAVGYLFNANDLHNENF-ITVGNTPRLIDLETFFQPEF----
--------SFLMAPNNRRWANSVLPMGVLPYRIGNGPD------SIDVGLVRSRPT-PGA
RHPFPSFMVRTLDDGSRTFIKEDTLPADP----EGTV---FLGTTIP----EIDRVKDQV
KSAFIDTA-RR--IVDKLDEVR---KIVAAARG-IRTRVVLTPTFRYAQVLATAGHPAIA
DD---------PFLFTLA-----CAQISLWGNDGVW-RSEWAGLMNDEIPLFTMGMTDTE
VVL---GDGAPLPFPQEKPVASASPAAHLESKL-ADATADGLAEQCRWLETSF-------
-------------VGRYPENRIHAATDSARN--MSHPRSKLVSHIVNMVLQ---AA--GA
NDEAVFGTDFLSATVGEEFDRNWQVGP--SNDDFYGGSAGTLYFLAHLMQHTYRQWVPSD
-------QI--EQLL----EKAVAGMVTATTPEPP------RADYPTGLC--TGSSGLL-
LTAVACGDAIGWV-------SGGREHIARQCANGAI----AVATHARNANLDDINV----
--DAINGLASQLRAYAEI-----AEYLPE--VRPNLRELARVTRRV--------------
------------------TRKWLRNYPESPDD-----AGYAHSTAGVLDAYLAASHLCGA
-----TVDTGLVEQ----QVQAILAAIHA---------------------------TGNV
SQGW-CHGMAGFGFLAA---HLCDHID---------TRA------AGESLLSAIRPGLLA
PVDHLGL----------------SVCHGVAGLAESL-MSLYT---ATGDE--EILDRARY
LIDEAIPADLVGD------------GLTK-----ENYSVSLM--CGVAGVG-QLLLSAPI
VAAPWHPVE-RMNVLWQKTA---------------------------------------
>NZ_ACSH01000028.1|c1|60666-63380|-|ZP_04837724.1|conserved_hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MTQIPI
ELRRAA--------------SDAV--------------------SDCLGRIIAGNLSRAD
FAAAMHDQLLKIDEVG-------EWPQSEV----------VADAA--GGQ--WRNVVAQ-
-----IAGRWYNDLAVASKYRVRSNSALAIRLVMAHRHVGAAAARLEQRI----A-----
----------EELPDTPNRVVLGLG--DAHSRQQTVARVEFA---D--------RQLIYR
PHSMATDQVIADICRLVGA-----------------PEPPHAFDMGDHGWSEFLT--AGP
GVTDE---AEFYAAVGAWAAVGYLFNANDLHNENF-ITVGNTPRLIDLETFFQPEF----
--------SFLMAPNNRRWANSVLPMGVLPYRIGYGPD------SIDVGLVRSRPT-PGA
RHPFPSFMVRTLDDGSRTFIKEDTLPADP----EGTV---FLGTTIP----EIDRVKDQV
KSAFIDTA-QR--IVDKLDEVQ---QIVAAARG-IRTRVVLTPTFRYAQVLATAGHPAIA
DD---------PFLFTLA-----CAQISLWGNDGVW-RSEWAGLMNDEIPLFTMGMTDTE
VVL---GDGAPLPFPQEKPVASASPAAHLESKL-ADATASGLAEQCRWLETSF-------
-------------VGRYPENRIHAATDSARN--MSHPRSKLVSHIVDMVLQ---AA--GA
NDEAVFGTDFLSATVGEEFDRNWQVGP--SNDDFYGGSAGTLYFLAHLMQHSYRQWVPSD
-------QI--EQLL----EKAVAGMVTATTPEPP------RADYPTGLC--TGSSGLL-
LTAVACGDAIGWV-------SGGREHIARQCANGAI----AVATHARNANLDDINV----
--DAINGLASQLRAYAEI----AEYL-PE--VRPNLRELARVTRRV--------------
------------------TRKWLRNYPESPDD-----AGYAHSTAGVLDAYLAASHLCGA
----T-VDTVLVEQ----QVQAILAAIHA---------------------------TGNV
SQGW-CHGMAGFGFLAA---HLCDHID---------TRA------AGESLLSAIRPGLLA
PVDHLGL----------------SVCHGVAGLAESL-MSLYT---ATGDE--EILDRARY
LIDEAIPADLVED------------GLTK-----ENYSVSLM--CGVAGVG-QLLLSAPI
VAAPWHPVE-RMNVLWQKTA---------------------------------------
>NZ_ADBR01000052.1|c1|3324-6293|+|ZP_06184907.1|conserved_hypothetical_protein
-----------------------------------------------MGNKKKVLSGEFN
SSDKTFSLLLKCLSEMENIMRKLSDNA-------------------VARTLSIPERNKLK
Q--------------------NPKISENDSFMHIFRQLSIFKNSMYHLDELLSPLCTLKQ
LESLSHEDSESLSERMQNHALPEWSTVFERWA----------------RTIGGESTSGHH
GLLSIIENHVTAA---TQELRTTL-------------VTEHGGYGEKLSNVLADSIPVDI
LTQIVAPSTLL------------VYKRDYS-----------------DKS--MQEYYAI-
LGEPSVRDAIYTEFPVIARLVTEVLIDWIEASTKLGEHLIQDKSLLLREF----G-----
-----------FDVSRLSRITANLG--DRHNNGQTVAVLES----DM-------QKVVYK
PRNAFGERLIYRVCKLLPE------------LNDLLPHIPVTFEKDDYLWQEFFA--AKD
FEPRQ--APVIAKKLGVLNAILYYLLADDMHHENI-LISGENVIVVDAECVLNTTR----
--PIDFMTIDVENVGAKVLADAAYTVGIVPQRVNSKVSGAN---PLDISVIGYKPG-GTV
ELNVPQIHST-PDGGYS-LINGPAQFN------ENDP---ITHRHL------LLQYGSDF
LEGFKLAA-IL--MMNRKEKIL---DTVLSSSE-LVVRVLPRPTMVYSKILLESFHPTFM
RD---AALRDA-CLGKLL------PRYFGKSYRRLLIREEMAALRGARIPYTELDLRNNS
F-----------VIESHRFSAECGGVNRIINHI-LDIDEDEIHRQCAYIDMSF-------
ASTILKSSLPVESIKILTKTYSWDCTRYSQKERLEEHIFEGLENVMNLLIR--------H
RGNVGFATM---NA---LTPDCWVLGP--AGMDLYNGLAGIHLMFERVRHEPFAEK-FLS
-------LY--DEIE----HTGLLFGDAVSLDKAS--VDKNVQALNVGLF--DQLAGIAV
SQY----LSLQQV--------KHRERASESLKRTLS----MLTSMVPYDKNY--------
--DVISGSAGSIFLANSL---------PLDYQEAVNKLIRQSIDKI--------------
---------LSAAQVTADGAFWPAQDSVSGL------TGLSHGASGIAAALAVGGKASKY
----------RVEE-CAEMIGAALEWERR---------------------------HFDF
EKGW----------------EDLREES------------------------------QSK
EQSEQLQ----------------AWCHGTGG------AYIAR------------------
---QIIADNNDAG----------LSGDQR-----RYLDQELQ----------YAVRK---
LAKKP------------------------------------------------------
>NC_003265.1|c1|25128-28025|+|NP_478385.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVLFYKKEVYPELNKSDFK--------------
-----------EHILPLNDFIEELSEPFSEFI---------------LEDSDLIEKEELY
PYHNACRIIAEGVW--RHTWDTKL--------------NKYTLNPSEFKKATCEFYS-QV
AFSYLIRSFAKD--IK-------LFKLSND-----------SNTD-------YDIYTKYL
IENK--FQDFSQTYNVVWGRCLKLLINRAKSIVKTIELINQNRNEIERIF----D-----
-----------IPNSHKIVSINTSG--DTHNNGSSVSVVNFE---KE-------LKLIYK
PRPISGEVGYSKLIEKLNC-----------LVSSKF-SSLKVLDLGGFGFTSYIE-----
---KN-EMNKNMKEAGRIAALMYFLNSSDMHYSNI-YWTNNGPIPIDLETLFHPKR----
---IADSNLENFNNAYYKIEKSVYGTGILPIHLTKKSSDV----SVDVGFTGVRDENSNS
PFKTFNIEDG-FTSNIKVVWQKQIEIDNSLYNDENYEKF-------------IYSNCKDL
IEGFTEIY-MI--ILNNKNYFI--NCVLETFDN-SKLRYIHNMTYRYEQILRILTDSEPS
KN----IDLAHMLLSRIG-------ILSMTSNKNIV-SSECTQLWNGDIPYFSISFDQKA
VES---EN----KFVT---WLPKSPKEEFMIKM-NSISLEDLNRQIEIIKLAF------V
AKLADPHRDEQILESEINEDVYIDKKTIEHS--ISYFMNSLTERIMNDRYN---------
HLPKTWIGP------VSQYGKGWTPGV--LGYDLYSGRTGPFLALLLSGKQLKNQK-VID
-------VA--YEFF----------DKVTKIFEEKTYDLRNLLMSGIGAF--SGMSGII-
WSL----YTAGKI-------TENSKWKN-TALKVFD----LIDEEIKKEEKGDFF-----
--DMISGSSGAIIMRYKI-------------QEDYSLSENFIKEKV--------------
---------KEAYNIINNKKNLS--------------SGLAHGISQIMYFFAIIYKKQKL
----------VYIR----RIIEDIHKIIKSNFTNVQNLIE----------IYRSEDKNNI
SSSW-CNGLSGLLVSYY---EGYKAGI-----------------FSKDEVID-----IIK
QIEIIPL--------SVVP----ILCHGSLGVYDSL-KYVSK--------------DFEK
ETRYLLMKLEKTTCSPAYIVNYFKEGRGR-----YTLSPGLM--TGKTGAL-LHLCK---
LLDGEI----DVSPLTFEV----------------------------------------
>NC_001949.1|c1|28174-31116|+|NP_047321.1|lacticin_481/lactococcin_biosynthesis_protein
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MKFNKNVFPEINETDFDNNIKPL--------
----LDELESRITIPQEELSFSSINDDLFREL----------------------TRNEEY
PYQSICTIVANIV---MDDGSEIW-------RKDIFVDS------NSVREAVCDILS-QT
LFLYFIRCFSEQ--IK-------DIRKTDE-----D----KEST--------YNRYINLL
FSSN--FKIFSDEYPVLWYRTIRIIKNRWYSIKKSLLLTQKHRVEIDKQL----D-----
---------IPHKMK-IK-GLKIGG--DTHNGGATVTTIFFE---KG-------YKLIYK
PRSTSGEFSYKKFIEKINP-----------YLKKDM-GAIKAIDFGEYGFSEYIE-----
CNTDEED----MKQVGQLAFFMYLLNASDMHYSNV-IWTKQGPVPIDLETLFQPDR----
---IRKGLKQSETNAYHKMEKSVYGTGIIPISLSVKGKKG----EVDVGFSGIRDERSSS
PFRVLEILDG-FSSDIK-IVWKKQQKSSSS---KNNLIV-DHKKERE-----ILQRAQSV
VEGFQETS-KI--FMKHREEFI--SIILDSFEN-IKIRYIHNMTFRYEQLLRTLTDAEPA
QK----IELDRLLLSRTG---ILSISSSPY----IS-LSECQQMWQGDVPYFYSKFSSKS
IFD---TN-G--FVDE----IELTPRQAFIIKA-ESITNDEVDFQSKIIKLAF--MARLS
DPHTTN---DNKLNKKVIIESN-QQSNSSES--GNKAILFLSDLLKNNVLE-DRY----S
HLPKTWIGP---VAR--DGGLGWAPGV--LGYDLYSGRTGPALALAAAGRVLKDKD-SIE
-------LS--ADIF----NKSS--QILQEKTYDF----RNLFASGIGGF--SGITGLF-
WAL----NAAGNI-------LNNDDWIK-TSNQSML----L-LNENMLKVDK--NFF---
--DLISGNSGAIGMMYLT----NPNFYLS--RSK-INDILLTTDCL---ITE--------
--------MEKDET-----------------------SGLAHGVSQILWFLSIMMQRQPS
----------SEIKIRATIVDNIIKKKYTNSYGEIECYYP-------------TD-GHSK
STSW-CNGTSGILVAYI------EGYK---------ANI-----VDKSSVYH-----IIN
QINVEQL-----QHD-NIP----IMCHGSLGVYESL-KYASK---YFEIE---TKYLLDV
MRNGGCSSQEVLK--------YYGKGNGR-----YPLSPGLM--AGQSGAL-LHCCK---
LEDNDI----SVSPISLMT----------------------------------------
>AF062647.2|c1|2355-4733|+|AAC19356.1|unknown
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MKS
KFGKIYIDYLYDH--VLEDVKKNI-------------------DVNIKEMPVIKEKVENE
IFVKCFKSLVYC--MN-------LARVEEK-----L----IGESP--EDR--YTFFCEN-
--EDAIIGGMEKIFPEMKNQISEEIRGKICYLIKVVDDFVNNYKEISKKF----L-----
-----------LENEQIKNINVG----GDWHNDKSVIIFEFT---KG-------SKIVFK
PTHGRNIEFLKGLSTIFLG--------------REYSSLYDSLTTDEGTWVKFIE--HKA
IKSEA-EIKEFYYNYGKLLYMTYILGINDMHYENL-LANGVYPVITDVETIFSSYL----
FFNIHKLEYDAQYNATKKLLYGTMATGLVPVFTMSEYF------GGDVSCLSN----RGL
KIMVEKLENE-YRDDMC-IKVAEDMVKSD----SHLP-----NNDID-----PLDYGKDI
LQGFNEAD-EI--FRNNKQKIY--KYIDDNFDK-VESRIILNMTKAYSKILRIKNDVKYR
MN---PELFKE-LLGKLK--------RTNQFNKKVY-EHEIAELMNGNIPSFYWSAKEKC
VYGPVDSSVE--KIMD----IKGFDIEDVKDIIEYQTADNIIEEQKNLIENAI-------
--ISSKVLSINYIEKSGKDKSIKAKPATEKM---------LRENIDKNIIL-------GK
DNTIAWLGL--------MVNDQEQLEYAMVDWSLYSGISGIGLMYYTEWLNTGDRN-AVA
-------VM--QLIV----------NTIKKEYELG-----RFDTYDISYF--CGLTGI--
YSF----IKKVEK-------IPGIELFG-LKESFEK----LIEKNIAYTNCY--------
--DSLSGVHSAVIYYYGD----YKENYFS--RKIITSITYHFMENF--------------
-----------NMRMMDATFSF---------------ASFAHGYTGLMTSLLCMNRVVKD
----D-----RFSI----LIKKAWEKEKK--LKVSDFKWV-----------DKRRADGSS
SHYW-CHGSCGIMQARL-------------------------------------------
-------------------------------------FWYKE------------------
----------------------------------EF------------------------
-----------------------------------------------------------
>AF320327.2|c1|1-2305|-|AAK73192.1|putative_ruminococcin_A_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MHKKFCG
LYIEYIFEYIIET---LKEKEDYL--------------------FDSEKIKYVKEIIEKE
IFQRVFKSLLYC--MN-------VERLDGN-----L----SGNTP--EER--YEMFSNT-
---RYCIEAMGKNFPTMRNQIYDEMAHKCVYVMEVIRELENNKNKIGRHF----------
----------GINPGEIVQVQNS----GDWHDSECVLIFTFQ---SQ-------DKIVYK
PTRGENLQFMKGFMDYFFE-----------PEYAEQ-YIGLCIRKGT--WVKFVK--HIE
LTNSR-NVERFYYNYGKVLFVAYILGMNDIHYENL-IACGEYPVITDVETIFSSYL----
FFDTHTFLYDAQYKAVKELLYGTMATGMLPIFSMTDYF------GGDVSCLSN----KGI
QLIVEKIKNE-YRDDMY-ICTAPEMIVEY----KHLP-----NHTID-----PLMYGKQI
VQGFEEAE-NN--FGEKKVEII--NYILNNMGK-VESRIILNMTKGYSKIVRIKSDPRYR
HE---PELFGH-LLTTLK--------RTNQFNPEVY-EQEVTELCRSNIPSFYWKMDMNC
VYGLNLGQKK--KILD----LPIFTKERLSEILEYQINIQMLEKQKQLIYDAI-------
-----------VSNIALGIEYEKLKISVKQH--VDIHVKKVLRRNIDQNCI------VGS
DGTISWLGL--------MVNDKEQLEYAMLDWSLYSGIIGLGYMYISEYDKEPDVL-AKD
-------ML--QRIF----------CTLAKSYDLG-----VFKEYDISYF--CGLTGIYA
FLK----QIKDRN-------IIEPDIIEKYIKNIQE----AIRNNIVKTSSY--------
--DTLAGIHSAVIYYFGC----YEQ------DIFSREILSSIEEYF--------------
---------LNSFKIDDMKRNFNY-------------ASFAHGYSGVMTSIMCMLQHKYD
----I-----KLEK----ILCELWKEEKE-------------------------------
------------------------------------------------------------
-------------------------------------LYVEK------------------
----------------------------------------FI----------WKDMR---
----------A------------------------------------------------
>AJ276653.2|c1|6551-9295|+|CAB93674.2|RumM_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MHKKFCG
LYIEYIFEYIIET---LKEKEDYL--------------------FDSEKIKYVKEIIEKE
IFQRVFKSLLYC--MN-------VERLDGN-----L----SGNTP--EER--YEMFSNT-
---RYCIEAMGKNFPTMRNQIYDEMAHKCVYVMEVIRELENNKNKIGRHF----G-----
-----------INPGEIVQVQ-NSG--DWH-DSECVLIFTFQ---SQ-------DKIVYK
PTRGENLQFMKGFMDYFFE-----------PEYAEQ-YIGLCIRKGT--WVKFVK--HIE
LTNSR-NVERFYYNYGKVLFVAYILGMNDIHYENL-IACGEYPVITDVETIFSSYL----
FFDTHTFLYDAQYKAVKELLYGTMATGMLPIFSMTDYF------GGDVSCLSN----KGI
QLIVEKIKNE-YRDDMY-ICTAPEMIVEY----KHLP-----NHTID-----PLMYGKQI
VQGFEEAE-NN--FGEKKVEII--NYILNNMGK-VESRIILNMTKGYSKIVRIKSDPRYR
HE---PELFGH-LLTTLK--------RTNQFNPEVY-EQEVTELCRSNIPSFYWKMDMNC
VYG--LNLGQKKKILD----LPIFTKERLSEILEYQINIQMLEKQKQLIYDAI-------
-----------VSNIALGIEYEKLKISVKQH--VDIHVKKVLRRNIDQNCI----V--GS
DGTISWLGL--------MVNDKEQLEYAMLDWSLYSGIIGLGYMYISEYDKEPDVL-AKD
-------ML--QRIF----CTLAKSYDLGVFKEYD-----------ISYF--CGLTGIYA
FLK----QIKDRN-------IIEPDIIEKYIKNIQE----AIRNNIVKTSSY--------
--DTLAGIHSAVIYYFGC----YEQ------DIFSREILSSIEEYF--------------
---------LNSFKIDDMKRNFNY-------------ASFAHGYSGVMTSIMCMLQHKYD
----I-----KLEK----ILCELWKEEKE--LYVEKFIWK-----------DMRAHHIVH
SHYW-CHGSVGIMMARL----IWKKFGFDKKFAEDIEEE-----NLEEILSK-----YKE
ELLNKKF-------QSKNY----SLCHGNFALIDFL-ISYRK---IVGTD-----ERIDA
YIEEIIESGQENG--------YSCVGAPG-----AINSIGFM--VGEAGIQ-YTENR---
SENSK-----LHSVLMLETV---------------------------------------
>NZ_ACEZ01000137.1|c2|257866-260664|+|ZP_05533031.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MTEPHVSIPSFL
PFYRYAIPRDTVA-ARLRVLTADV---------------SDPDRTELLLDQVWQDLI-TT
VEGHAFRMLIGE--FH-------EFREQLG-----L----PMDAD--SDR--ALQLFRRH
VEHPGNNQRLIGKYSVLKQRLETVLENSLDAYADLFTAYAQDRTTLRNHG----L-----
---------LSADDDPVMELFGTGS--DLHNHNRKVVGVRLA---SG-------TKVVFK
PRALISDRFVRDLYTTAAP----------HLVYSLQECVPASITIGSHGWQQFVT--PRP
MSAPD-QPARYYYRFGALCALFGAIGASDLHDENL-LAAGENPCVIDTETMIRPNA----
----GVDNDSLPHVLINQLKLSVVSTMLVPMANPSSPI------DLIMAGVGIDGE-QTS
KMKRAVIRES-ASDGIS-VQWEQVTHRPG----DNVP-R-LGESALS-----PLDHFDDI
VAGYDDA------LGAVRDDAV--AKVLDSYPD-MPVRCLVRSTMVYTRFLDAATHPDYL
RQ---PEDAER-LLRLLG----KYPDYLTPEAAAYVGEEERTSLNTGNVPYFAARGGSTE
LAT---PTS---QLPG---VHKTSPLDFARSGL-ILNARRSGVFHRFLLEECF-------
------GEVAADDPAGASAWSVFAEALRDAR--PAAWWPGIARTIASAGVS--HEG--PQ
GMEIGWVCG------IGPDRNAPTITP--GNFISFHDVGGIVTFLTNAARHDEALREAAV
-------GA--NRGL----------DVLIEEYGEL------LAEASEGVF--TGGASLL-
--------------------LTRPSHVDRAQMDRIL----DTIDDRAAAGTLES------
--DLANGPAGPLMVLLSR----LEGGEAPLVDQERLARLRRLVLSH--------------
-------------IEVSKAFPW---------------YDVAHGDLGMRWASSRIGRVLGD
----S-----ALVN----ASADWLADQPA-------------------------DGNALP
VPGW-CRGTAGLLLTSA---EILTSAG---------RQE-----LLTGARLT-----ALA
DAATRLP---------ADQPVDLSVCHGSSGVIQSL-IATAQ---ILRDN--SLLDRAAD
YQERVLAAARSNG---------FHTGSPG-----RTSLLGYM--LGWSGIGDTDIML--Q
AARAGVVDLAIPIALFTPHPSGEPA----------------------------------
>NZ_ABYS02000009.1|c1|73525-76617|-|ZP_04448254.1|hypothetical_protein
------------------------------------------------------------
--MYADTIEERYSLIDDDDAS-------------------------GDDSFVDSVISQWM
S--------------------RNCALRPDDFASMLELRGYDKKKYAKCID----------
---------GKSFLKGNKGNLSSWYSDFEKIF--------------AFFSNSKFVEDINV
GYVNIFMPFILYA---EKTLRTTI-------------PDSQMNSYDNVQNSIRGTLA-NR
LLNIGLKTLVLE--MR-------RENADGN-----L----QGTDG--HER--MLSFIHM-
ASTYAYQRLLYSRYPVLARMLTQATTDYIAFIREMFTRLEESDSELKMFL----K-----
----------STVPLVLSDIRLDGG--DAHNHGRTVAILEFN---NG-------SKVVYK
PRDLSIHVLFADLAHECER----------SDDFLPL-HVSRVLPEDGYAFEEFVR--QSQ
CLTCD-QVSRYYLRIGELLALVWFLHGNDMHYENI-ISDGEYPQIIDYETVCSNYV---E
MDSQNSLRETADVKVARRLRDSLAGTSFLPTRMVLNAEGE----SIDFSALNVKD--QEV
PTLFPVPVML-DTDGAC-FQKQHVVFSKK----DNVLH--YNDDVVN-----PSDYAHEI
LDGFTRGV-HA--LGRISDDAL--CRILQRGKA--TVRVLVRATSVYARFLNYMHHPKVL
DD---MTKVEA-ILENLY--------VFPYKNKHIF-LSEYQQMIHGDIPMFATSLDSKI
LRD---GEGR--ECGP---SFAYSAIERIMRT--KRHLHEEASLQESLIRNAF-------
------------------HMPVRQRQAISSS--INEWPLMIGHYLVDQAIL----S--DD
GSTVSWICT---KQSGESENDANAVGV--PSPDLYDGCGGTAIFLASLSQAFGDRR-CAD
-------YA--LKTM----------RSIQLRTSPS---------ASESAF--TGGLSQI-
YPA----LMLRSL-------GIKSDILTNSALQIMDRLERYVKDESVRLSKVGKANRFTY
RMDYLAGASSVIILYLRI----WELLR----DDDILIQLSQLGRIV--------------
---------AKTACRLQREENANSDDSFP--------AGAGHGLEGISVALWRLYAAVGD
----T-----EFADDAQKIWEKAMAKHKA-----------------------QPVRSSRE
RGKW-CRGTVGLLWAQNEIDRCTACGR-----RFFDDAG-----KPFPEFSS-----VKQ
LIDSCDW---------VDD----SLCHGRSGAIDVL-VSLAR---NTNDE--RYSALARH
LMDDMVAAASCNK--------HFDFGKVC-----AFPNMSVF--LGPLGVA-YAMLR---
VQNPD-----VPSLLSLEI----------------------------------------
>NC_010816.1|c1|1983009-1986110|+|YP_001955594.1|Lantibiotic_modifying_enzyme
------------------------------------------------------------
--MAATAMPDALRQYRA-----------------------------SHAEDMLSATVEWK
N--------------------RRNPLRDEDYQGIADALGDDASVVETVIA----------
----------DRERKLSGHVEPAWSVELQTIL---------------NRYDSEEERVERT
GYATAFAPFVAYV---KAELQAHM------------SACSLPMNDERLIEQCLSAYV-ER
LLSIGLKTVVWE--LH-------VARQAGS----------LGDGD--AKRQLRRYF--EL
LATDEYRGHMYAKYPVLLRFVTQTTVHYIDFVKEMLDRVSMDRDELASFA----------
---------GVGDDFRLEDMSIDRG--DAHDGGRAVAMLTI----GG-------RKIVYK
PRDLHIHELFAGLVRRCER----------TKGFLPM-RVSDVLTKSGYAYEEFVE--HGT
CEDAR-QVERYYTRYGQLLGLVWLLHGDDMHHENI-IASGEYPMVVDFETIATNHV----
-TMDMPDGTDADIRVSTILRDSLASSCLLPAKTAMSADGT----SVDISAFETGE--QTM
PGIVASPVGL-DSADAH-YERNAVTFS------KDGCAVTLDDAVVD-----PYHYKRQI
LQGFRNTVAAA--MTIDADEW----DAMLSGED-TTVRVLVRNTSAYARFADFIHHPSAL
KD---MLDVEA-ILENLY--------VYPFRDKRIF-ASEYRQMLAGDIPMFTAQLTGHD
LHA---PDGT--TIDG---VCERSVRERVLDTI-GHLDEQA-ALQSRIIRNAL-------
-----------RMEPGMEDAHPTASVSSDTD--AEHYPIELGTRIADTAIL------QET
DGTVSWLTANRSDTMAADKTVDERYEPGAPTSGLYDGMAGTGMFAAELYRRTHDER-WRD
-------LC--TRMM----------RSLMRRKDRG---------ITYSGFT-SGLSRSY-
CALRMANAGITSP--------EARRCMTQTVRMLPAYIDDMLPKLLQRDNPQPSFHL---
--DYLTGAGSSIMLYLRL----YDVFH----DMRIVEQTSRLGRTV--------------
---------IRAFPETQRNADESDDMPYP--------TGAAHGLEGMAVAFWKLYAATGN
----R-----EFAE----FARMLWRKSDA----------------------RRSGAKQED
AGKW-CRGKVGVLWARN---ELAATAGADGERFFEDENG-----RAFPDKAD-----ITA
LLGNADW---------DDD----GVCHGRCGMIDTL-ISIGN---ANGDE--WYRMQAQR
LMDDMIAQARSSG--------RFRLRQSR-----EFVDLSYF--QGPVGVA-YTMLR---
LNDPS-----TPSILALETR---------------------------------------
>NZ_AABM02000034.1|c1|4244-7270|-|ZP_00206332.1|COG4403:_Lantibiotic_modifying_enzyme
------------------------------------------------------------
--------------------------------------------------------MEWK
N--------------------RRNPLRDEDYQGIADALGDDASVVETVIA----------
----------DRERKLSGHVEPAWSVELQTIL---------------NRYDSEEERVERT
GYATAFAPFVAYV---KAELQAHM------------SACSLPMNDERLIEQCLSAYV-ER
LLSIGLKTVVWE--LH-------VARQAGS----------LGDGD--AKRQLRRYF--EL
LATDEYRGHMYAKYPVLLRFVTQTTVHYIDFVKEMLDRVSMDRDELASFA----------
---------GVGDDFRLEDMSIDRG--DAHDGGRAVAMLTI----GG-------RKIVYK
PRDLHIHELFAGLVRRCER----------TKGFLPM-RVSDVLTKSGYAYEEFVE--HGT
CEDAR-QVERYYTRYGQLLGLVWLLHGDDMHHENI-IASGEYPMVVDFETIATNHV----
-TMDMPDGTDADIRVSTILRDSLASSCLLPAKTAMSADGT----SVDISAFETGE--QTM
PGIVASPVGL-DSADAH-YERNAVTFS------KDGCAVTLDDAVVD-----PYHYKRQI
LQGFRNTVAAA--MTIDADEW----DAMLSGED-TTVRVLVRNTSAYARFADFIHHPSAL
KD---MLDVEA-ILENLY--------VYPFRDKRIF-ASEYRQMLAGDIPMFTAQLTGHD
LHA---PDGT--TIDG---VCERSVRERVLDTI-GHLDEQA-ALQSRIIRNAL-------
-----------RMEPGMEDAHPTASVSSDTD--AEHYPIELGTRIADTAIL------QET
DGTVSWLTANRSDTMAADKTVDERYEPGAPTSGLYDGMAGTGMFAAELYRRTHDER-WRD
-------LC--TRMM----------RSLMRRKDRG---------ITYSGFT-SGLSRSY-
CALRMANAGITSP--------EARRCMTQTVRMLPAYIDDMLPKLLQRDNPQPSFHL---
--DYLTGAGSSIMLYLRL----YDVFH----DMRIVEQTSRLGRTV--------------
---------IRAFPETQRNADESDDMPYP--------TGAAHGLEGMAVAFWKLYAATGN
----R-----EFAE----FARMLWRKSDA----------------------RRSGAKQED
AGKW-CRGKVGVLWARN---ELAATAGADGERFFEDENG-----RAFPDKAD-----ITA
LLGNADW---------DDD----GVCHGRCGMIDTL-ISIGN---ANGDE--WYRMQAQR
LMDDMIAQARSSG--------RFRLRQSR-----EFVDLSYF--QGPVGVA-YTMLR---
LNDPS-----TPSILALETR---------------------------------------
>DQ145752.1|c1|1423-4224|+|AAZ76597.1|BhtM1
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MCLLEDINASINELEVYEIWNRFHLLSS-----------------------NTFSN
LYLSFLEPYLFEIRNQLQKYDDSF-------------------QSDTIERTITENML-EN
IYSLSEGIWIAE-----------MRNINKN-----------------QAE--YLAYLNQ-
--DYKNLAEVVKKYPYWYFSIILFIRDTTKYLLEFLSHLIQDKALVANQF----L-----
-----------EADGMITDIKLSMG--DRHRGKFVIKVESEF------------GNYFYK
PRRSKLDTLFKEVIDKIGD----------QDGILKM-KAPKIIDQGSYSWAEEIR--YIP
LQSKN-KNERYYIRLGQLLAIAYILNGSDLHYENI-ISCGEFPVAIDVETLLTSRL----
RFKKQMTPKMLQEDNINYLEDSVSNLIILPTIVKSNGD------FYDLSPLKIYSG-ELP
NTFAETWKKS-----------------------NHLV---QKNE--------LKDVIDFI
QRGFTNIY-NE--VLKDKERYK--EYFNRLFNN-IPIRYLNRETHDYSQILRLLKNPVCL
FH----FKYAFAVSMKLL--------SEEIQEEEVQ---EYKEMLKFNIPYFELNTGSTD
LLL---SNGE--KIKN---YFIETPLESLEYKL-NLLCEEDLERQLRLITQML-------
-----TVVSTEFDVKEINEVTIHEGENPQKQ--RAQTIEQMIATVFENKLI----N--PL
TKQYFWITP---ELEGDNNRSFYQIHE--NPDSYYSGSVGILRCLLLLEKSGYKDLPINK
-------LI--SDIE----------IDIDKIIKYG------TSDISIGAY--NGVVEYL-
-------RYYAYI-------YKHNNFSDVLSLKRIH----YLLDLIENSFKKDEKL----
--DILDGTAGVILTLIEI----FQLHLSDCLNNRVIKLVEKCRLHL--------------
---------IDSIIYDKGEVYFPIAQEKKRYF-----TGFAHGSSGITLAIYRANKLLDI
----D-----DYT-----LIQSLLKTERR-LFDKTNQMWF------------KDNNRNSY
SWGW-CHGIPGILLSRL---ELIKHGY---------QDD-----YIIEEAYE-----LYE
IAMRKSL-------G-VNL----TFCHGDLGNLVIC-KYAEA---ILNIEYSKVEIYIQE
ILPYLLNSMEYNI---------------R-----GTETVGVM--HGLVGIA--TFLDSTI
CDNYLR----LLDILKITSD---------------------------------------
>AB179778.1|c1|1389-4265|+|BAD72771.1|modifying_enzyme_for_proSmb
------------------------------------------------------------
------------------------------------------------------------
----------------------METRTDNIFIKLSDNSNIEKLYKKFGMN----------
------LLEDINASIDEFEVYESWNRFHLLGS-----------------------NTFSN
LYLSFLEPYLLEIRNQLQKYDDNF-------------------QSDTIERTITENML-EN
ISSLSEGVWIAE-----------MRNINKN-----------------QTE--YLVYLNQ-
--DYKNLAEVVKKYPYWYFSIISFIRDTTKYLLEFLSHLIQDKALVANQF----L-----
-----------EADGMITDIKLSMG--DRHRGTFVIKVESKF------------GNYFYK
PRRSKLDTLFKEVIDKIGE----------QDGILKM-KAPKIIDQGSYSWAEEIR--YIP
LQSKN-ENERYYIRLGQLLAITYILNGSDLHYENI-ISCGEFPVAIDVETLLTSRL----
RFKKQTTPKMLQEDNINYLEDSVSNLIILPTIVKSNGD------FYDLSPLKIYSG-ELP
NTLAETWKKS-----------------------NHLI---QKNE--------LKDVIGFI
QRGFINIY-NE--VLKDKERYK--EYFNRLFNN-VPIRYLNRETHDYSQILRLLKNPVCL
FH----FKYAFAVSMKLL--------SEEIQEEEVL---EYKELLKFNIPYFELDTDSTD
LLL---FDDK--RIKN---YFIETPLESLEHKL-NILCEEDLERQLRLITQML-------
-----TVVSAEFDVKEINEVTIHEGESLQKQ--RAQTVEQMIATVFENKLI----N--PL
TKQYFWITP---ELEGDNNRSFYQIHE--NPDSYYSGSVGILRCLLLLEKSGYKDLPINK
-------LI--SDIE----------IDIDAIINYG------TVDTSIGAY--NGIAQYL-
-------RYYAYI-------YKNNNFSV-LSLKRIH----YLLDLIENGFKNDEKL----
--DILDGTAGVILTLIEI----FQLDLSDCLNNRVIKLVEKCRLHL--------------
---------IDSIIYDKGEAYFPIAQEKNRYF-----TGFAHGSSGITLAIYRASKLLNI
----D-----DYTL-----IRSLLKTERR-LFDKTNQMWF------------KDNNRNSY
SWGW-CHGIPGILLSRL---ELIKHGY---------QDD-----YIIEEAYE-----LYE
IAIKKSL-------G-VNL----TFCHGDLGNIVIC-KYAEV---MLDIENSKVDKYIQE
IFPYLTNATRYHI---------------R-----GTETIGVM--HGLVGVA--TFLDSTI
CDNYLR----FLDILKITSD---------------------------------------
>U91581.1|c1|2764-5532|+|AAC72258.1|LctM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MKKKTY
QFEKFLKNTFDQF---SIKQNEVL---------------------------VEDDLN-DI
IMNVCGKALVLM--IN-------EKREMNL-----L----MGNTP--EER--YQYFENEY
SSTGKAFEEIKDKFPVIYIDLKNSINSYLKLVSQIMKDFKKDYSLLVERK----I-----
---------IEEHST-IS-TMKIKG--DLHNGKAVIEITTNK------------SKLIYK
PKSLSNDVFFNNFLKYMDSFFIKEGKST--KYKENF-YLVNTLDMKTYGWVEYVD--KKP
INSFE-EARNYYRKIGVLLSVAYTLNLTDLHFENV-ISQGENPCIIDLETMFNMPM----
--FVKDYKNESRNIINGKIMDSVVSTGMLPVLGIDSLF------GGDPSGILG----GTF
SKEERVIINP-FRDDIK-FQKIVVRSVFK----DHIPFFNNNNEKRY---CKPKDYVNDI
IKGFEKTY-KI--IVKNKEKIL---GFLKKESSSVTCRILFRNTMEYSVLLNAAKSPVY-
-----SNKREE-IFEKLS-------TFNRGLGNDII-KSEISQINTLSIPYFNCQVDSNL
IKN---MDGE--TIFE----HTLTPFKCFLSKY-RRLCVDDMEQQVKLIRFSI-------
-----QSQEQLFKDGEQFSLYK-KQKGSQED--LLIAINELSSILENNAYI--GT----S
DDTINWMSL---GI---ADNDQILFES--LENDIYKGISGIGLALLEYYEFYPNIN-TKK
-------IL--KLIY----KNIS--KDFINTNNEP---------QNYGFY--VGLIGE--
YSFLRKYEKVFHK-------TSSCNILKNILKDFTP----EKCQTI--LPSD--------
--DVIAGEAGIIIYISNL-----------NNYLEYRDEIDILLKSL--------------
----------------SNKIKLKESI-----------ASYAHGNSGIATAFVHGYKVTKN
----E-----KYLK----IFHELWNLENS---SKLRRGWT----------DSRKV-DSSY
SSQW-CHGASGQAIARM---EWITVNKTARFLSNSELIK-----VKK-ELGE-----LID
ILKKEGM------YT-DNF----CLCHGILGNLLIL-NTYQE---NFDNKNINLKNEILN
NYYSVCNYGLNKG--------W-ICGLGT-----EFYSYGLM--TGISGIL-YGLIR---
QVKQKN----NFGVLMPYVD---------------------------------------
>AB121757.3|c1|1901-4654|+|BAC98760.2|NukM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MNNIKVEQFR
GFSNFI----------LKKYSK-----------------------QELNTLIDWNYLRSI
ILDICGKSLIVL--IN-------EKRLNKK-----L----NGNTP--EER--YKYFDEEL
CEKGIIYEELNKSYPSIINDLEQTLNSYFSFLKEIENKFNQEKKKLLEAN----L-----
---------IKTEKETICHISI-LG--DLH-GGKAVTKVTT----DK-------SQLLYK
PRSLENDSFFLEFLEFMYS---------FQKNEISTYYKYKFIDYKDHGWMEYIE--KQP
TSKNK--INMYYKRLGYLLSIGYLLNISDLHFENI-LCSSNFPILIDLETIFHTSI----
--YESKFRNLATKNIEDKAANSVFATGMLPISKKDKKY------GGDISGILG----GVF
NKHERTISNP-NRDDIK-FEKRLVRVKRN----DHIPFYMENDKKRR---FSPEVFIEDI
QEGFKYGY-EL--FLNNRKEIL---HYIKKTSSEVEVRILPRSTIEYSVLIQAAKSPLYA
NK------RKS-LFNKLE------EYGENLLSDKLI-NSEIKQIETLSVPYFYTKVQSVS
VKD---------IKNNTVHHLLKNPLNVFLEKT-QRYSLKDLLFQCKLIKFSL-------
------ESQNKLFIDGNGFINYEYEIVNSDN--IDDAIDNLVSIIINNAVI----D--EK
DGSVNWMNL---GI---SKEEEIIFES--LSDDLYKGLSGIGIALLKYYEINKNLKDMSR
-------L---KKILSSIYSSIL--SNINTNSSKE---------KDLSFF--NGEIGKIA
FLY----KYQIEF-------KENCDSSKNYMKHILG----IILSSEFEMN----------
--DIIAGLPGIISYLYN--------------QEIFSKELVIMGDRL--------------
----------------------LKDLDNNPTM-----ASYAHGKSGVMVSLLYLYDLTKD
----K-----KYLV----KFHQEWKKENT---LKLEIGWK-----------DVRQNEETY
SVSW-CNGVTGQLISRLVALEIHDKVK----IFDAVNKK-----LMQKEIEE-----LLY
LLKEEGL-------EQNNF----CLCHGVMGNLLVL-NYYQK---KFENTNIHLANKIDS
HFYSVANFGLNKG---------WICGLGN-----NFYSFSIM--TGISGIL-YAFLK---
YKTKDT----ELGILLPNI----------------------------------------
>NC_005207.2|c1|19224-21977|+|NP_940773.1|NukM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MNNIKVEQFR
GFSNFI----------LKKYSKQE-----------------------LNTLIDWNYLRSI
ILDICGKSLIVL--IN-------EKRLNKK-----L----NGNTP--EER--YKYFDEEL
CEKGIIYEELNKSYPSIINDLEQTLNSYFSFLKEIENKFNQEKKKLLEAN----L-----
---------IKTEKETICHISI-LG--DLH-GGKAVTKVTT----DK-------SQLLYK
PRSLENDSFFLEFLEFMYS---------FQKNEISTYYKYKFIDYKDHGWMEYIE--KQP
TSKNK--INMYYKRLGYLLSIGYLLNISDLHFENI-LCSSNFPILIDLETIFHTSI----
--YESKFRNLATKNIEDKAANSVFATGMLPISKKDKKY------GGDISGILG----GVF
NKHERTISNP-NRDDIK-FEKRLVRVKRN----DHIPFYMENDKKRR---FSPEVFIEDI
QEGFKYGY-EL--FLNNRKEIL---HYIKKTSSEVEVRILPRSTIEYSVLIQAAKSPLYA
NK------RKS-LFNKLE------EYGENLLSDKLI-NSEIKQIETLSVPYFYTKVQSVS
VKD---------IKNNTVHHLLKNPLNVFLEKT-QRYSLKDLLFQCKLIKFSL-------
------ESQNKLFIDGNGFINYGYEIVNSDN--IDDAIDNLVSIIINNAVI----D--EK
DGSVNWMNL---GI---SKGEEIIFES--LSDDLYKGLSGIGIALLKYYEINKNLKDMSR
-------L---KKILSSIYSSIL--SNINTNSSKE---------KDLSFF--NGEIGKIA
FLY----NYQIEF-------KENCDSSKNYMKHILG----IILSSEFEMN----------
--DIIAGLPGIISYLYN--------------QEIFSKELVIMGDRL--------------
----------------------LKDLDNNPTM-----AYYAHGKSGVMVSLLYLYDLTKD
----K-----KYLV----KFHQEWKKENT---LKLEIGWK-----------DVRQNEETY
SVSW-CNGVTGQLISRLVALEIHDKVK---------IFDAVNKKLMQKEIEE-----LLY
LLKEEGL-------EQNNF----CLCHGVMGNLLVL-NYYQK---KFENTNIHLANKIDS
HFYSVANFGLNKG---------WICGLGN-----NFYSFSIM--TGISGIL-YAFLK---
YKTKDT----ELGILLPNI----------------------------------------
>DQ889451.1|c1|19442-22243|+|ABI63640.1|SboM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MENTEKNK
LFNKFTRNFIQTN------------------------------FSEYDMQNCEIEFLEDK
VLDIYMNTLILL--IN-------EKRLLGI-----L----KGSTS--EER--YEYFNDV-
LCGKYIIDEIAKRFPKLVSRSLTQLKNYLLLYRKVEQLFLKDVPKLIQNR----F-----
-------ISNQCENFKMEDLQITVS--GDFHNGSGVCILFY----KG-------ERVIYK
GKNNFANQLLIEIFSKLGD-----------EFEESLEFLPRYIDCGDYYWEEYIE--HTS
IRNSNISASEYYKRFGYLLAVAYLLNISDLHFENI-LASGDIPKLVDVETIFNLQP----
--YEILSETIADKDLLKRNAESVLLTGLLPLAGSNEVF------GGDTSGILG----GKF
VGEVRVIQNQ-MRDDIS-VKRQVVRKTNK----SHLPFYISEGEEQY---FEVKDYLREL
LFGFKKVT-SY--VENQKNTFL---SIIEKYSEKIDVRILFRNTKDYSIVRTLLLSPKYS
EN-------DNIIFEKFK------NKLVNYQSDELC-ESEIKQLEQMDIPYFSMKSNSCD
VYD---LYGN--AVWS----TYYSPIELIRKKI-QNLSVHIIEEQYKLIEFSI-------
------SSTLRLYNQEALPRINDVEDKSYSDSILYKGVQNIVDRLLGAIYL----S--NS
DQTCNWLTL---SI---NNVDCLELSP--MDCTLYGGLSGVALALIESMTLLEED--YRK
-------KV--RSVL----PYLY--NSILKKYEYL---------TNDSFY--MGRMGVL-
YTL-----------------KKLSKEVGKDLDNWVN----IEIDNVISRLNIGDT-----
--DFLTGISSVIPAIRL--------------ENLNKVTFEELSDIY--------------
---------IKQAKEKDNFVFWGNEQSNN--------VSLAHGNLGIELALVRLIKVLDN
----S-----NNKETISTLLKKAINFDNL---QRREHGWV-------------DNRNFSH
SANW-CHGATGVLLSRI---DLYNQLK-------NDKTATISSTDLQQDVIH-----SLQ
DIKEVGL-------NLANF----SLCHGVSGNLLTL-VHTQN---FFDENNIVNNYNLKK
FVRENFYKIHLYG-----LQNGWMCNFNT-----KYDSYALF--TGISGIL-YATTL---
YLKNDI----KSDVLLPNIVS--------------------------------------
>GQ857551.1|c1|11811-14594|+|ACX68644.1|SivM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
KYNQLYEQFDKFP---LFIIKQKF-------------------NYKSLENSNNRKVLEKI
ILDYYRPTLIYL--IN-------EKRVNGE-----L----KGNTP--EER--YDYFNQEL
CGSGKIFGEIEIRFPEINDRIELIVKKYLDLHERVKSTFVKDFRFLCDNK----F-----
-------LHSDKLKPDLDKLEIEVT--GDIHDGAGVCIISY----NN-------QKVVYK
RKSSIANRFLRKIDLMVSE-----------FFNEEIRFIPNILDRDGYFWEQYIN--NQK
LKNAN-EAREYYTNMGFLLFYAYIFNISDLHFENI-LSSGKSPILVDVETLFSTSP----
--FEIIADNFATKEITQRSRSSVLSSGLLPISEAEKIF------GGDLSGILG----GTL
VNEFKTVINN-YRDDIR-IEKVVQATKYQ----SHLPFFEYLGQKEY---LVATNYVNDI
IAGFKLVS-DF--FLNHKEEIL---EVYQQYSD-LKTRILFRNTHEYDVVSQLLISPIYS
QK------QDL-LFKKMS------EKLSHYDSSKLC-ESEVRQLLSMDIPSFYIEANSTI
VTD---GYS---DVWK----IRKTPLYSVTEKL-NKLTEDKISEQVELIRFSL-------
---QADRDSESTEMQELYKKYD-DFRNEENI--MINALNNLVDEILAKMYL----D--PD
DESINWMTL---KV---NDHNNFELVP--MDNSIYDGISGVALSLIECYSLLDKNRKRKV
-----------YRCL----CYLF--KTLVNVYSNI---------LDMTYY--VGRLGIL-
STL----VRISQI--------TKQEIPQKILNSKVS----LINQALQNTPA---------
--DFLTGFSSSILACEE--------------DEYSEEFLRTMINRF--------------
-------KELKQYDSNHNYIYWGKEESNN--------VSLAHGNAGIEISLLYLAGKLKS
----R-----DAKE----MYEDAKKFDDK---QRLDQGWI-------------DKRFSDS
NAQW-CHGSTGVLISRLAQLKLNQEFK----ILSIQEES-----LLVEDIQH-----AIK
QIILIGF-------DMNNF----TLCHGVGGNLLAL-TYYNNLYGGENSS--ELEEIINS
EYRKMLSFGIKYG---------WMCSLNT-----NFDSYGLM--TGLAGII-YSVSK---
YLKSDS----SLEILTPVF----------------------------------------
>DQ889747.1|c1|2452-5235|+|ABI54435.1|SivM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
KHNQLYEQFDKFP---LFIIKQKF-------------------NYKSLENSNNRKVLEKI
ILDYYRPTLIYL--IN-------EKRVNGE-----L----KGNTP--EER--YDYFNQEL
CGSGKIFGEIEIRFPEINDRIELIVKKYLDLHERVKSTFVKDFRFLCDNK----F-----
-------LHSDKLKPDLDKLEIEVT--GDIHDGAGVCIITY----NN-------QKVVYK
RKSSIANRFLRKIDLMVSE-----------FFNKEIRFIPNILDRDGYFWEQYIN--KQK
LKNAN-EAREYYTNMGFLLFYAYIFNISDLHFENI-LSSGKSPILVDVETLFSTSP----
--FEIIADNFATKEITQRSRSSVLSSGLLPISEAEKIF------GGDLSGILG----GTL
VNEFKTVINN-YRDDIR-IEKVVQATKYQ----SHLPFFEYLGQKEY---LVATNYVNDI
IDGFKLVS-DF--FLNHKEEIL---EVYQQYSD-LKTRILFRNTHEYDVVSQLLISPIYS
QK------QDL-LFKKMS------EKLSHYDSSKLC-ESEVRQLLSMDIPSFYIEANSTI
VTD---GYS---DVWK----IRKTPLYSVTEKL-NKLTEDKISEQVELIRFSL-------
------QADRDSESTEMQELYKKYDDFRNEENILINALNNLVDEILAKMYI----D--PD
DESINWMTL---KV---NDHNNFELVP--MDNSIYDGISGVALSLIECYSLLDKNRKRKV
-----------YRCL----CYLF--KTLVNVYSNI---------LDMTYY--VGRLGIL-
STL----VRISQI--------TKQEIPQKILNSKVS----LIKQALQNTPA---------
--DFLTGFSSSILACED--------------DEYSEEFLRTMINRF--------------
-------EELKQYDSNNNYIYWGKEESNN--------VSLAHGNAGIEISLLYLAGKLNS
----R-----DAKE----MYEDAKKFDDK---QKLDQGWI-------------DKRFSDS
NAQW-CHGSTGVLISRLAQLKLNQEFK----ILSIQEES-----LLVEDIQH-----AIK
QIILIGF-------DMNNF----TLCHGVGGNLLAL-TYYNNLYGGENSS--ELEEIINS
EYRRMLSFGIKYG---------WMCSLNT-----NFDSYGLM--TGLAGIV-YSVSK---
YLKSDS----SLEILTPVF----------------------------------------
>DQ835394.1|c1|6540-9326|+|ABI30229.1|McdM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MNQKE
QLYSQFDKFPKVV---IERLIPEV---------------------LNESDSLIKQIE-EK
ISDYYRSTLIYL--IN-------EKRINGT-----L----VGETA--ELR--YDFFNNVL
CRNGTILDEIEERFPKINQRVFISIKHYLDLLNCVKKHFVSDFLELKKLK----F-----
-------LKSNDESPDLNVLDIKVT--GDIHNGSGVCILDY----NR-------QKLVYK
KKSSRPNILLKELDSQASN-----------YLKKEIRFIPDFLDKNEYFWEVFVE--SKP
VSSLK-EANEFYKRMGYLLVYSYILNISDLHLENL-ISHSIQPILVDAETVFSTNP----
--YETVAENDATLKIVENSRNSVLSTGLLPISEADKIF------GGDTSGVLG----GTL
IGEAKVIINH-NRDDIH-VEKQKYKTENQ----NHLPYF-ESNLGIK-TYLNAEEYVEYI
KEGFIELS-KF--IINNKEALK---KLYLSFSD-IKTRVLFRNTRDYSLVRQLLLSPVYC
NQ-------DNILLEKMS------NKLTNYDSHNLC-QSEVKQLLNMDIPYFYVCASDIN
VKD---KDGNT-NIWK----LKKSSLSDTIEKL-EKFDLDTMEEQLDLVEFSI-------
------KTPNALYSTELQESYKIFQNSNSNHSILFTGINTIVDTILKNEKF------SKL
DGSTNWLTL------KVTDYDAFQLEP--MDSSIYEGIAGLSIALCEVYELVDDDRQQRI
-------YNCLRRIF----------MTLMKAYYST---------QNQSYY--VGKLGIL-
SAM----IRTQSI--------TGQEIPVSIFDINNK----YILDLNVQSA----------
--DFLSSFPSEIVALRN--------------SNVSIGNLQQSFEKL--------------
---------VDLKIISEDYIAWDKLESNN--------VSLAHGNLGIELGLLYLAVALNS
----S-----EAVE----LFYQATNFDSH---QKLSNGWI-------------DKRNNST
SANW-CHGSTGVLAARLAQLQLDKKFH---------TISKTKRSELEADMKH-----AAS
QIIEIGF-------DMTNF----SICHETSGNLLALSYYCSY---LSGNEREELEKILDI
EYRKLHSFGLENG---------WMCSFNT-----KYNVYGIM--NGLSGIL-YSTAK---
YLKKDD----SLDILIPTL----------------------------------------
>AF026542.1|c1|3050-5833|+|AAB92602.1|ScnM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MNPKE
LLYSQFDRFPKVV---IENNFPEL---------------------LNESSELIKDVE-DE
ISDYYRSTLIYL--IN-------EKRIEKN-----L----IGDSP--ESR--YEYFNNVL
CQNGLIFEEIDRRFPSINQRVMSTIKKCLELINFVKERFTLDFKELRETG----Y-----
-------IYSEAQTPKISEVKIKIT--GDIHNGCGVCILSY----EE-------QKVVFK
KKSSNPNVLLHELNIEVGK-----------FLQKDIDFIPDFLDKGEYFWEKFVS--SSP
LRTEE-DAKEFYRRMGYLLSYSYILNISDLHFENL-ISTSFSPKLVDVETVFSVSP----
--YQTVANNESTLEIINNSRNSILSTGLLPVSEAGKVF------GGDTSGVLG----GTL
IGEAKIVINH-NRDDIH-VEKQKFKTENQ----DHLPYF-IDSKGMK-EFLNAEDYVEYI
KEGFREVS-YF--FMNSQDFLK---KLYIKHND-IKTRILFRNTRDYSLVRQLLVSPVYC
EQ------SEI-LFETMA------NKLSEQNSRSLC-LSEKKQLLNMDIPYFYSNIDSCD
IKD----ENM--IIWN----LESSALSEAINKL-EKLSEEIINEQIELIEFSI-------
------KTPKALYSTELQEAYQKFEKVSSSENIIKTGIDTLVDIILENESN------SLK
DDSTNWLTL------KVTDYDAFELVP--MDDSLYEGLSGIAISLSEAYDFLDSGRQRRV
-----------KECL----KRIF--SVLSNSYMKL---------PNHSFF--VGKLGIY-
SAL----KRISVV-------TGQEIQNSIMNYNNLK----YTLDVDVLSA----------
--DFLSSFPNEITALRN--------------SDIKIDNLTQALDKL--------------
---------KELAIVQKDFISWDKLESNN--------VSLAHGNLGVEIALLYLAGKLES
----P-----EALN----LFHKAKMFDKH---QKLENGWI-------------DKRNSST
SANW-CHGSTGVLVARLAQLKLDDEYS---------LLSYSERIELENDMKH-----AAK
QILEIGF-------DMTNF----SLCHGTSGNLLAL-TYYQSYLTGADSE--KLKEILDR
EYRKLHSFGLENG---------WMCSFNT-----KYNVYGLM--TGVSGIL-FSTVK---
YMKGDD----SLDVLIPNF----------------------------------------
>EF060238.1|c1|1243-4029|+|ABK59358.1|MukM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MDQKE
LLYSQFDVFNKQV---IERYLPEV---------------------LDESDDIIQDIE-EQ
ISDYYRSTLIYL--IN-------EKRIDGS-----L----IGSSP--ESR--YNYFTNVL
CQQGMILDEIEERFPTITQRVVISLKKYLELSKYVKEAFTADFSELLAEG----Y-----
------LDGVASDISSDDVKIKITG--DIH-NGNGVCIVAY----QG-------KKVVFK
KKSSQPNQLLQTLEREVSQ-----------YLDKEVYFISPFLDKGEYFWEKFVS--SKP
LLSEE-EAKEFYCRVGYLLACAYMLNISDLHFENL-ISSHINPILVDVETVFSTST----
--FDTIANNDATFKIIESSRDSVLFTGLLPVSEADKVF------GGDTSGVLG----GIM
IGEARIVINH-NRDDIR-IEKQKYKTENQ----DHLPYF-SDSEGVK-TYLNAEDYVDFI
KSGFSELS-EF--FMHRKEFLK---TLYSEYGH-LQTRLLFRNTRDYSLIRQLLTSPVYC
EQ-------SHVLFEKME------DKFSEVDSHELC-QSEEKQLLNMDIPYFYAEIASRD
VRD---DEG---IVWQ----LTRTALSQVIKKL-DNLSSAVINEQLDLIEFSI-------
---KTPNALYSTELQDAYRDFE-NNQQTQDQDVLISGINELTDVILENEKN----S--QE
DGSTNWLTL---KV---TDYDAFELVP--MDDSVYDGLAGMAIALSEVYDLVDDIRQEKI
-----------RLCL----QRIF--TTLSNSYLEL---------QNQSYF--VGKLGLF-
SAL----SRISPI--------TGQELPDFVLDGDQD----YLVDLDVSTA----------
--DFLSSFTNEVVALRN--------------SDIKIGNLNQALDKL--------------
---------DELKIISEDFISWDKLESNN--------VSLAHGNLGVEVALLCLAGNLER
----P-----EALQ----LFRKAKRFDDR---QRLENGWV-------------DKRNSDT
SANW-CHGSTGVLVARLVQLRLDDRYK----LLSPSERT-----ALEADLQH-----ASK
QIIDLGF-------DMTNF----SLCHGTSGNLLAL-SYYQSYLPENDAQ--RLRAILDK
EYRKLHAFGLTKG---------WMCSFNT-----KYNVYGLM--TGLPGIL-YSTAK---
FLKGDD----SLDVLIPNL----------------------------------------
>NC_013928.1|c1|350881-353667|+|YP_003484244.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MDQKE
LLYSQFDVFNKQV---IERYLPEV---------------------LDESDDIIQDIE-EQ
ISDYYRSTLIYL--IN-------EKRIDGS-----L----IGSSP--ESR--YNYFTNVL
CQQGMILDEIEERFPTITQRVVISLKKYLELSKYVKEAFTADFSELLAEG----Y-----
------LDGVASDISSDDVKIKITG--DIH-NGNGVCIVAY----QG-------KKVVFK
KKSSQPNQLLQTLEREVSQ-----------YLDKEVYFISPFLDKGEYFWEKFVS--SKP
LLSEE-EAKEFYCRVGYLLACAYMLNISDLHFENL-ISSHINPILVDVETVFSTST----
--FDTIANNDATFKIIESSRDSVLFTGLLPVSEADKVF------GGDTSGVLG----GIM
IGEARIVINH-NRDDIR-VEKQKYKTENQ----DHLPYF-SDSEGVK-TYLNAEDYVDFI
KSGFSELS-EF--FMHRKEFLK---TLYSEYGH-LQTRLLFRNTRDYSLIRQLLTSPVYC
EQ-------SHVLFEKME------DKFSEVDSHELC-QSEEKQLLNMDIPYFYAEIASRD
VRD---DEG---IVWQ----LTRTALSQVIKKL-DNLSSAVINEQLDLIEFSI-------
---KTPNALYSTELQDAYRDFE-NNQQTQDQDVLISGINELTDVILENEKN----S--QE
DGSTNWLTL---KV---TDYDAFELVP--MDDSVYDGLAGMAIALSEVYDLVDDIRQEKI
-----------RLCL----QRIF--TTLSNSYLEL---------QNQSYF--VGKLGLF-
SAL----SRISPI--------TGQELPDFVLDGDQD----YLVDLDVSTA----------
--DFLSSFTNEVVALRN--------------SDIKIGNLNQALDKL--------------
---------DELKIISEDFISWDKLESNN--------VSLAHGNLGVEVALLCLAGNLER
----P-----EALQ----LFRKAKRFDDR---QRLENGWV-------------DKRNSDT
SANW-CHGSTGVLVARLVQLRLDDRYK----LLSPSERT-----ALEADLQH-----ASK
QIIDLGF-------DMTNF----SLCHGTSGNLLAL-SYYQSYLPENDAQ--RLRAILDK
EYRKLHAFGLTKG---------WMCSFNT-----KYNVYGLM--TGLPGIL-YSTAK---
FLKGAD----SLDVLIPNL----------------------------------------
>EU497962.1|c1|3798-6311|+|ACA51935.1|BovM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MEKLDLTINNESE
SFHKIIDNIVSDF---YLVILDAV-------------------QTNAELSNVHKYLY-KN
IRQVLLPILAQD--IN-------EWRLESK-----H----QKNDT--NQE--YIDYCYL-
FISKNRFAYLKNKYELLNLRIDTIISETKLNLKNFLKNIDKSVSSLKKVF----P-----
---------QCDFEIKKLKFIDFIG--DNHGLYQSIMFEVSG------------KVFFYK
CHGSEITNFIVTLQKEIPS--------------LNFLKLPTTYIDQEFIIQEKVT--HSS
VLIKD-DIEEYYHNMGKLLGILYLLNGNDMHNENI-IARGKNPIVIDVETLINPIE----
------------CDSDSKMDDSIFSVGMLPMKYNRNFEG-----IFDTSSLGQS---NIV
SEKVFKEYKP-FTSEIQLVLIDHTFSDLD----RYLP-R-YKEIHFD-----VIDYLGVV
EDGFIESY-HL--IMNHKKEIA---KVISREASNINCRIVLRNTRIYSEILKFLSTPSLL
KN---ITKAED-TLKRLL-----VKPRYIIHNWERYRQQEIKQLLNGEIPYFSFGKYGNT
SPN----------------DLNLSSVETSLQCKLNRFSDDDLKFQLILLRTSL-------
-------------NIDDDNFEIIGKENFRGK----------LKDLIKSSIY---------
--GTDIFTL--------QKDWCGNYIYGESNLGLYEGKLGIILSDSYFSDIFDVSS----
-------IR--REIL---------------------------FSRDISFI--DGRASLDV
FDI-----------------INNDSILSPVSVEISN----KYL-----------------
--DLIEGISGVILVRYKF----YCQKLPE--NISELEQLMRQFMRL--------------
--------YKNSSELK---------------------NGFAHGISGIKIIFYIAYQILGE
----E-----KYLD----EFKKLEILDFP---------------------------EKYT
NGSW-CNGLLGWITSEY---ILYTISG---------DKT------FKENILN-----HLP
RLMTYLI-------DLSDY----CLCHGSFGVLDFL-LTLSQ-KELLPKEFHDEYVKLEK
YHLEMITQCRILK-----------------------KDVSLF--TGISGIL-YYLNR---
KESGKN------SVLTFGF----------------------------------------
>NZ_ABOO01000006.1|c1|30250-32808|-|ZP_02952302.1|SalB
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MIKKSNIRENE
CFEVVIENISKTI---YKEVQRKI----QDIYRNKF---------LIILDKLYLEVY-QD
IRNLLIPILVQD--IN-------EWQESIE-----N----ESNDY--KKQ--YEIYCENF
FEGR--YTYLLNRYKRLADTINLYKVDLFFSINKFILNLIENRRKICLFF----L-----
---------LDTNKFIIE-FIKFVG--DKHSADRNICFKLNN------------IIFYYK
IRGMKVQLLADKINKEVFS-----------CK--YF-KFPKSIIFTNFMIQENVI--NND
CENIK-DIESFYFNTGVMLFYIYLLNGIDFHNENI-IADGRFPILIDTETVISTIS----
------------SKDIGDLGSSVFASAMLPMKYSKYYNG-----ICDTSGIGQK---NKI
LKKYIAFENP-FSSKIK-LKFIKILEDDIV---SFLP-K-FNGVNYD-----ALNYLHCI
VNGFQHGY-NL--AMKNKLAYK---RIIDNADN-LMPRFIFRNTCIYSELLQRLYAPDTM
KS---NIYTYN-FLKKFL---KNIPHVNSDKKEKYI-NQEIEQLLKGYIPHFKICSKNYI
LRSNSEEVLY--EDLS----ETLSVKKSLMTKL-MQLSKEDLFFQIELISVSL-------
-------------NINNHNFKK-INFNYNKP--ILRLIEESIHVINGKLLV---------
------LTL--------QKDWQGNYIYGNIKDGLYEGALGLLLAESQFNSYFSYQK----
-------IE--KNIL---------------------------DSKDIGLI--NGYSSIIL
YNY-----YVSNL-------EKEVYFLE-------D----IIFTQY--------------
--DVIDGLAGYILLVYRK----YIINKEELLLDYILKLIEKFMMFSIVNEEK--------
-------------------------------------IGFAHGLSGLKIIYIIAFKLTNK
----Q-----KYLD-----KYKVIDEKDD-------------------------I-SRYS
SGAW-CNGLTGYLVSEY------IMYK-----------------ITNKETHLIKIIDNLD
KLFIFAY------KI-DDY----CLCHGVFGILDFL-LTLQQ--NNLLND--EFKLKFKK
LEEDVFTTLDKKS---I-----------------LIKDISLF--TGISGIQ-YYYNR---
KKENRK------SILSLCY----------------------------------------
>NZ_GG658170.1|c2|1110293-1113331|-|ZP_04578914.1|predicted_protein
--------------------------------------------------MKMTDDMAFE
LSGKSRNLLEQGNA--------------------------------GCPEQLKEWFDDWC
R--------------------ISFDGDVQSFHRRLSLFAGATA-----------------
---------LAERDDSGTQRIARWVREIEKIN--ALMPTTRQRILSRIQYNPFGGDDLPE
DFFSFIAPVIVYL---ENRLKPVF------------------GLKTKNGDAFLEEAACQD
IVTNGTRHILQIYDFF-------SLDALNDMAPGIL----PLPFP--ALKKYYDAFSSQM
LDGG--LAGAFHECPVLGKMTIDYIDGYVGHLKECLSRMLHDSDKLRETF----G-----
------------CSGEISRLGLSQG--DSHNGGRSVVIAMFA---NR-------VKVVYK
PGNGRLDKAFEAFTDYLAE----------IGAIWPV-KLPKLVCAEDYCFKEFMS--HDP
LPSKE-AARRYYHRAGQLLCVVTLLGASDLHAENV-IAHGEYPVIVDLETVVTPVV----
---KRFATQDEDEIDKKGTGNSILDSGLLFARFDGF--------NGDKGGIAVT------
-----------HSDGMN------------------VPFF-ADRQEID-----DEDICSGL
KEGFEQTY-RA--MLKQQDSII---EKLNVFSG-CDCRFLVRPTQLYVDLLKQIRYPDAL
KD---GMSQGFEIEKSFS-AFSCCPDDAVLQKLYAVYEAEFLSLVKGDVPYFYTSTNKLS
ICS---GTNE--LYDG---YFEKSALENARECF-RGMSESGLSLQLHLLKRSL-------
-AAVWISEEKRPSNAFVFSSEDKVRRLTVAE--MLEEAERIFQDILDSAIR--------I
NGEQTWFVS---EIAA-SDASDEAISQKLMDNSFYNGFSGLSVFAGALYQSTGQQK-YRD
-------YA--RKWL----EKCF--QDAGRLKGKQ----------HGGVT--NGLGGLL-
MAS----ALLAQY-------LNEPQWLV-KANVLAE----AGLELSPEP-----------
--DYMSGLAGYIMALDRI--------------GARATLMTEVAEKL--------------
---------LALAKTVDGFHVWQCDQNSRPL------LGFGHGQSGCALALKKVFDRTHE
----R-----KYLD----AALSAMAFERQ--WHREGKGWP--------DLRLSDDSAFDG
MCGF-CTGGAGIGLASL---DMTGISR---------EID----EWMLDNIGF-----AIE
SVKRFDM-------Q-TSD----TLCCGNMSRVHFL-VSAGI---RLDRP--DLIDEAVN
RMSWVAARKKRFG--------HYILNTKA-----ELTEVGWF--NGLAGVG-YELLR---
LVKMGQK----------------------------------------------------
>FP929038.1|c1|162636-165566|+|CBK79125.1|Lantibiotic_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDIRELIKIINQNEEAKQFWKKFLN----------
--------KDILDELLKYPELLSMQDVKRAKIAKEEKEFFLKCIFSVSTENGIKFEKEER
VFDSFYEKLGQYI---KIVLKQKL----------------IASLTENMIDSLVKQIV-QR
VFWIPFRCLIAD--MH-------EKKDAGQ-----L----NGHSS--AEE--YDDYVSKY
LLNERECGEFLKKYPVMTDLLIRKIGDYINYVNEIFHHFYQDRETISKEF----H-----
---------IEQNAMKITKISFNQD--EEHFPERMVARVRLK---GG-------QKIYYK
PHSLLLTERYQKIENWLWE-----------KMGLEE-SRHLVVSGDDYGWEQEVT--EAA
CKCTK-EIKEFYYRCGAECCLTYVLGMTDIHMDNV-IAHGKYPVIIDTEFMFDRRI----
------EAGIQGKNLQQNLMDTVIHTGFVPNGMGTL--------HINVSVLNTCDE-QRL
SVKMPMVINK-GTSEMN-ISYHYPKLSHK----KNMP-I-YEGKYIS-----FENYMNEF
ISGFRRAY-DC--IKADPEVLVGMCQPIMK----KSVRYLFRNTQEYYMYITSFNFPELM
RN---QAKRQLSLWHMNR-----GLHCNETYRVKIL-TYEMQCVYDGIVPIFY--ADGKN
LLM---GDDE--YIEN---YFQRDNEQQLKLRV-EKLSDWDKDFQTKVIQSAL-------
-------LMYDKKKENWNGQLGQPQSKIGEL-----TAERIAKWVFNAAVL--------T
GDKMEWTSV-------IYGKDGWTKAGK-ADIYLYNGLSGIFLFFEAMWQKKHENF-YHS
-------VV--EQLK----------KQLCEHTDILIQNGSNHQSDRMGLF--DGEASVA-
FTY----WIMYKL-------TAEESYIV-YAKKQCQ----FVLDNDYQVTSD--------
--DLIQGRAGIIILLLLM----YKTTQ----DKMYLDIAQKVGTNL--------------
---------VESIQSKNCL------------------AGMAHGYSGMAVAMALLGRYTGE
----G-----NYKE----IVLELCRKEDQ-LFDCSMNNWL---------DIREGREHPRN
TVAW-CHGSAGILLARALIHKISGLTM---------DQL-----FKDIPLNQ-----VID
QMCQTEK---------TDW----CLCHGQAGLLIVE-RYIRH---VFGYEEEKWYENAAK
YLDKRLSIE-------------------------DVLNYGIM--QGLAGIGIFLLFWEWE
RDKDTK-----------------------------------------------------
>NZ_ACEX01000498.1|c1|20532-23537|+|ZP_05517469.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
-----------------------MSAVLRTYFPEVTSSELRERIRGRILH----------
----AVTAGDMAGDVGEGGREEERCEAGQPGP---------------YEPSLDADGRLRD
YFRHFVKPWADWI---RESVRSSP----------------VVDSANTIADDFLRAQT-VT
VAELMIRTMVGE--LY-------ARRSRGL-----L----DGQTP--EER--YESFRQW-
TNSEAGHRELTDRYPLLFRTVSRRTEESARYLLTVVREVEYGAWELPAPL----P-----
-----------VGEIKVSAIELGEG--DTHNGGKSVARVVFT---DG-------SRVIYK
PRSMASEAGFNAFVAWMNG-----------ELGLGL-RTVATLPVRHGGFAEFIP-----
TQEHTGGAENYFAQVGSLAGILFLLKATDIHFENM-VTCADGPVVVDAETLFTPTPRTRE
TGGDGAAPSPAPGLATRVLRESVVGTGLLPMVIRARGSGR----GMDVGAIGYDAG-QRL
PYKVLELRNR-GRDDMYVAMAAKEMTRAN----GNVAVQRATGPDVR-------VRRDLI
KAEFRRVL-EH--AAAHPHRVM---DAVERFLGDAQFRFVSSPTLFYGQLLRMATHPDAI
TS---PLVRAA-VLHRVA--------LRTTDVPGVV-EEEVRQLAAGDVPYFSYTARSRA
LTA----QGRTVCADA----LEEAPLDSVRDRI-LRLDTTVIERELDLIDFSF-------
-----VDKLPTEPEQTGFKPRAGGARNAVGESRYLAEAERIGDRLVATQIG---GA--DP
LQPATWIAP---QVTT-DSQSQWTPGP--LGYDLYGGSPGPALVLAALAHETGRRD-YAD
-------AA--RRVL----DPIE--RQLRGDHLDD-------AAISVGGM--TGMAGTV-
YAI-----------------AVGRELLGDRDGTRLS----DLAGKIARRCGPDALP----
--DYVSGMAGTLAVCMAL----YGRAESADEKRAVEESVRTVAAAE--------------
---------VAVLGGTDRADARVTGH-----------TGLAHGAMGIGPVLIQYGTVFDD
----P-----AARR----LGVRITGAVVD-AYDERDGDWP------------REWGGDRR
SYGW-CHGAPGLLQGGL---LAVSHA----------PSA-----VPVGALAR-----CAE
LTLDRGF-------G-NNP----TYCHGDLASADIL-AEAERQLPGLVGD--VAEDIYPR
LFAEVVEQYEKRA-------------DNK-----YAYSNSLL--VGQAGLA-WSILR---
HLDPVS----YPSVLWLE-----------------------------------------
>NZ_ACPD01000056.1|c1|22311-25391|+|ZP_04807200.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------MNNVKQLNINMK
SFTQTLTIEERLNAFKENQL--------------------------TTIEDTIILDEKWL
N--------------------IRSLVSPQVFIEELEHMDIKKEELAFALK----------
-----SFTDDEENILIEYLEKLDWFKLYKDLM----------------KQFETIYQNEPV
FCEQLVLPFKLFVKKELYNVKNDL---------------KNIKIEADLIEKLIDSIV-SQ
LDKLTWKCLIVE--IT-------DYKEENI-----L----EGKDG--RDR--YLNFLELC
YKSPTQIQLFYDKYPVLGRFVTQKMLDLLTSVKDMILDLDVNFVGINELF----N-----
-----------IGTNNIRDIKVSLG--DTHQQGKSVAEIQFD---NE-------KKYIYK
PRNSYIEKAFNKFIEFANK----------NSGLKDL-FINIVFYAKTFTIEQFIE--MQS
CKTIV-EVKDYYYRFGMLTALISLLSGSDMHFENL-IAHNQYPCIIDFETFFTQVN----
---FTHNIDDANVKVIDTQVLNLSGTGLLPMSFPMGHEGD----GIDISALSGGNT-KPI
TRKILIAKNV-HTDDMG-FEYENSYILNQ----NNNRST-LNGEFQE-----YKNFKGYI
YNGFNDTL-DW--ILKNIDELK--VFIKETFND-LQVRQVMKATAIYNNLVDYMDHPHYL
ND---MARIEK-LLENNW--------AYLYSDKRLV-KYEIMDMLHLEIPIFYTSTSKTY
LKT---SNGA--YISD---YFKEDVLSKVINTI-SNLTKEIAEKEQMKLCILL-------
---GDYSILVNERKKELAKEISKSNLRIYQDEEVIEVCNSIAEKIMQGAVI--------T
EKSISWEYI-------DDTEEISKFTY--LNNGLYSGRSGILLYFYYLNSIQKNED-IEN
-------FT--KGLI----------RDVRYYKEPV----------ENTVF--KGGAGSL-
YTL----LK-----------CDKDNNFKMIQDTIIF----INKDNMKMDKI---------
--HWLDGVSSLIKVIDNINKTKYK-------SDLVLKVADGVIESI--------------
--------CNNLDNQIVNTCS----------------VGFGHGLIGILYALLVGQLLLKK
----------DYNV----EIEKILALCEEQIHNLKAPKLL---------------DTSKD
ILSW-SNGIVGLGIGAL---GCKKYTE---------DSR------LDNYINL-----TID
AIKDYSF---------DEM----SLSNGLAGELDFL-ASLSL---IKDDP--LIKEMILM
KRNQMLDFYKRNG--------VFLIDELI-----QFRNYGLF--SGLSGIG-YSMLR---
TLFPDK----IPSVLTLD-----------------------------------------
>NZ_ACEZ01000137.1|c2|252828-255704|+|ZP_05533029.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MEEWLRGSEQYP------------FQHVVRTVAATLADTD
PLASFADLFADQ---------------------------------QAALVQLLERAE-VR
LRGVYMRPLVAA--IN-------HARENDL-----L----RGATP--RER--YEYFVKE-
SSRTSFTTVSGLSFPVLQDVTRILLRNETDSVGELCTRLRADRAAIEDTF----G-----
----------IDASDLLESFGLPEG--DTHHHGRTVAVLVFR---SG-------KRLVYK
PRDVSCEAAYVSIAGEVNA-----------HFGTSL-VAATVLERDRYGYVEYIE--AED
VSDIS---PEFLYASGELAAVLYLLNARDMHFENI-LPTRRGPLPIDLETILHPER----
--VHTGMIPEVTGNAYEMIAQSVYGIGILPLVMAGKGGDGG---HVDLGFLGAQGN-GNS
PFKAVQFKDP-YTDYIS-LAFQAAAAAER----RTVVNALTKHE--------VYDLGRHM
ADGFTKVY-RA--AMVDPDTWT---ALLRKTATDLRIRYVHNATVLYAQTLRMSSSPSAL
ED---TAPYLA-LLKRIA-------IASPASARQLV-RSELRQLAERDVPYFTVASTDTA
LMD---GEGT--EIGA---AFDRSPLDLVLAKA-ARLSEFDLSEQLRLIHSAF-----AS
RFPDNHLTPVAGLAPVPGRPGS-AALKSDNE--LKTVVRTLCDHLIATSLP---DR--FE
HLPRTWIGP---RASA-EADRPWPPCV--LGYDLYTGRTGPALALAAAGRLLDEGR-YRD
-------LS--AQIF----STTA--EILATESYET----RNIQQLGFGGY--TGMAGIL-
FAL----SAAGRI-------LGEDSWTR-AAQGAVP----LILDQV-SSVPPGKLPL---
--DVISGLAGAMSCITAI---------GG--PHA-NAAVTALTSILVDSFQG--------
----------------GASGEWLGPVLAQ--------SGFGHGISGILHALSRVHPRLSP
--GLR-----PLVE----STLQDLAGRLHGFFDAEERNWH-----------TSIDRPTSF
ATGW-CHGPAGIALALS---TYADVSG---------GNE-----VVR-MRDT-----AVD
YVLRQGF-------G-RNL----TWCHGDLGNHDAL-ITLAD----CGVT--SLRAEIEK
IEQRWLHPETFAR--------KLGDTSSR-----YAHTNSLL--VGTAGIV-LHLVN---
RVDPAGRI--SPTTFVASEGR--------------------------------------
>GQ900454.2|c1|35475-38552|+|ADA80223.1|putative_salivaricin_A_modification_enzyme;
-------------------------------------------------------MESTN
PLKRAANLTEMAEISSF-----------------------------KNDNNLNDELNNWL
E---------------------QSGLSKYDFEKKLYEKGISKDKFLEIIH----------
-----------SGPPTKLNFKNKWDEKLIYIL----------------NNFKGSKYTGAE
ILNSFSIPFYKYFIWEIKKFCKQF-----------PDLYIYILDIEKIILNLAERLN-NQ
LTNVCTQTLIWN--FY-------EFRKENN-----L---------------SFSNYLLIH
LNNNKNKYKLLEKVPVLARNIVEITENYITYIKEIIERYISDYTDIRKEF----L-----
----------EDKIVKLDSINIGQG--DTHKNGKSVAILNFQ---ND-------KKVVYK
PRSLSIDMGYNKFLKWLNT----------KKIKHKL-KIITSINKKQYGWQRYVE--NKE
CQTNG-QVERYYYRMGVLIGVLFTLNSTDMHYENI-IANGEFPEIVDLETIISNNI----
------YHSYEDNFPLKVVLNTILGSGITNTGSLFSETI-----DTDISALTGIPK-QKS
KKIKNSIINY-SEDGNPKLDFKYFETEEQ----KNLV-K-INGKWID-----PFEYMESL
KNGLLDCL-N---IVKVEKKYLVNELIDNCFDN-SFIRIVPRASQTYASFLNASYHPKYL
MR---GIDKEF-LYELLW---NVCKQEPKM--KKLV-NSEVIDLLNNDIPYFFTKTNSLD
LYN---SQNL--NLGR---LYTKTALEIIKEKV-SQIDRKFIILQLKLLELSL-------
------IDFKNKELTINEVEKL-SDTNKKFK--TNNYELEIGDCISNYALF--------D
HEKITWIGW-----FSDSSVNKFSLRS--ANYTMYNGSLGISLFLLELGRFYDNKK-YEE
-------IS--LKVA----------QFLINEAFNK------EKFLTVSAI--NGLGAIV-
YLS----FYIYSRTKNDWYYHQGVRLME-NLNNYNK----EKIPTK--------------
--DYMNGHAGIIHLLSNI----YRKFNIEKARSIACIYADHLSSYI--------------
--------YNHTNHFISSLIS----------------NGIAHGISGYRIAFENLNSLEDS
----------KYRN--IIKYLNKIENEKTALYNED---------------------NLKN
IGYW-CNGKLGMIYEKS-------------------YRE-----ILNCGVERKLDSNILK
ESKREIL-------NTERI----CLCHGTFGILNLL-ISLSK-----FNPTLIDIEVIRK
TRDRLLKSEEIRK----------KINYQI-----ETGQFGLF--IGISGIG-YTLLR---
TKDPS-----IPDIIHFDFPKEEDEVKNEKNTVY-------------------------
>NC_009480.1|c5|2221401-2224562|+|YP_001222710.1|putative_lantibiotic_modifying_enzyme
----------------------------------------------------MTITAAEL
SLLQASRLRERRAATR------------------------------ADARPVPELTRAWR
D---------------------DALVDDGTHAAYLAGQLLDGDDLVALLA----------
-----------GDAWTPRAASADWLARVDPWL-VHPPVSAEAYATANGHLVVEDTRVAGL
PFAALLGPMVGAQ---RAHLDGRP------------------WLSRTATADLLDGLA-ER
LATLSLRALLAE--LA-------RDPAPGR-----------------HAR------LDAR
LADPEHRAELLSRHPVLARDLVTAIGSWRAHVARILDRLHADHGDLVRMG----L-----
---------ATERLDALEAVDLSSG--DPHDGGQSVATLRFS---DG-------SLLVYK
PRDCRVFALYRDLVDALAP---------ALPGEIRL-RAAAVLPRDGYGWVEFVA--HAE
DAASAIPLSRHLGRLGSLLAVAHVLGASDLHLENV-IASADGPVPIDLETLIQNRS----
--EVDGEDGTALRRASRMLNASVLGSGILPVQLTTGEGT-----SIDVSVSTGGLHGAGT
TATVHQVVDA-ATDRMR-IEAREMPVGRS----RNQP---PGATLAR-----IRSGRAAL
ADGYERTF-RA--IVERRAEVR---AILSAAPD-ISSRHIVRATRSYSLLLTEMRRPRPL
RS---GIDRDH-LLRHLW-----TRVEEHPADAALV-EAEERALWRLDVPLFSTRMDARA
LIA---DDEE--AGPQ---RFARSTREDVLDRL-ARLTLDDLPESLRLVDESVLAATATP
DGDDDARDDARGRQAADATASL-ARAPRVDDDALREAARGQARILLASAVL--------G
RDDATWIGV-----SSSLDSSGLEYRP--AGPTLYDGLAGIAFAATHAHGVLPGLG-LDD
-------LA--GRAM----HAVT--AILDDWTRGL-------IDLPVGAY--SGATGLL-
HAL----AHHDAR-------VGGDGHRD-LRAAAVR----RLGEVAHEDPHL--------
--DVMAGVAGACAVVAGL---------PEGATEAGRHALRALAGRL--------------
--------MSTAVEVEGGALVWETGAERARL------GGFSHGASGVGWALARTAGVLGD
----D-----AIAD----AAVRALRFDDA-LFDPSRRRWR-------DARPEARSAAGSF
PAHW-CHGTAGIAMARA---DAAATLD---------RPD-----LLELALVG-----ARE
TASDALP---------SDD----SLCHGTLGNLIAV-RGATR---RTGVD-TGLAEFRDR
ALQRVLRAGPRSG---------LPQGVTS--------VRGLM--LGTAGAL-YALCR---
ELEPG-----IPDALLLEGPR--------------------------------------
>NC_013440.1|c9|2027054-2028367|-|YP_003265938.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MLVQVGR------------------------------
-----------DRQPS--------------------------------------------
----------------------------------------------------------YA
RANIAARVAYPARASWLYC-----------AT----------------------------
------------------------------------VAYLSSSLLVNVTA----------
------------------------------------------------------------
----------------------------------------------------------TI
AESMRSAH----------------------------------------------------
--------------------------------------------SEGDEPQREAKAD---
------------------------------------------------------------
------------------------------------------------------------
-----------------------------ASDDLYGGALGDAVFLAAYAQCSGAQW-ARE
-------LA--LRLA----QPTRRAANADTGASPQ----------RIGGF--VGVGAQI-
YGL----VTLARL-------SGESALVS-EADALAA----T-IELD--AIAA-DRKL---
--DVVHGSAGLILALLALDAAPHASP-EN--RAARLSRVRAACAHL---LAQ--------
--------QQAH---EPWRGAWMRSDSPVPQ------SGLAHGATGISLALTRAAAVLAD
----D-----ALLA----AAGAGLAFERA-HCAVAGGRWR-----------VAPG-DSRV
PVGW-CRGTPGGALGRH------LILVASRGAVP--EAA-----ALEREIAH-----SLS
YLSALPP-------L-PLD----HLCCGGMSVVDALLEFHHSDASWLSEPTKPLLALAHE
RATWILRAAKTRG--------HFSSGSE------SASDLSLF--QGLAGVG-YGFLR---
LAQPES----LPCLLSFA-----------------------------------------
>NZ_ACLX01000146.1|c1|3101-6178|+|ZP_04298130.1|hypothetical_protein
------------------------------------------MTIVVEEKNLKLDHYLSE
IFNKSMTIDEKIQFYNY-----------------------------QSEEVNCDKLKEWK
S--------------------IKSLVKDSHFEEMLNSRKLTEKQFAFGVS----------
-----------AMKLDVNHNFPFWLSLFKKMI------------------VNHTSSKDEK
GIIIAIAPFVNYV---KEKLKEKK------------NQTIHLSVEETVTDKFLESYA-LE
ITNIVSKIIVIE--LE-------IYKTENT-----F----KSENT--ENR--FDEFLQST
FNGKMAYAEFYSRYAVVGRLIATRTHFFLENYENLLLAIEECKSEICHLL----G-----
-----------KDELRLSDVNLSAG--DSHENGKSVIILNF----EN-------DQIVYK
PKNSSVSEGFEKFTSWINN----------SSNLLDV-KIPKGIYRDSFSFQEFID--YEE
CETQE-DVENFYLRMGHLIALSYILNMNDLHVENI-IAYKDYPVIIDGETLFHNEH----
--NLDLRDKPYAKIKLHISSETLMQSGLLPYSVQISDDHGN---LIDLSGTSGGN--NEI
IAKALKPVDF-NKDTFR-FENQEIKRKKG----NNIPKK--DNEYVG-----FKEYRHLI
IQGFLEMS-NF--IVEQKPLLLSEDSPLNYFKN-TKIRCLLKGTQTYSSILGFSSHPNYT
KE---MFYREK-LFENIW--------AYPHMDKRVI-LSEYNDLLNGDIPIFYSKVDSID
LED---SRGK--IIGD---FFRHSGLELSINRI-KNFDLHEIEYQLGFLLVSL-------
------EIVEENYIASKNNRKKLPSNNSKID--GLFYAKKIASKLEDKAVW----N--NR
HDEVSWMTI---DVM--MPSKRIGIHY--ANEGLYDGLSGISYYYLMLFIATKEDR-YFD
-------MY--KSVM----------KSAIDFANKC---------PLVSAF--EGCLSPI-
YPI----LIENKY-------LGSSTFNNYIFNTIEK----IDTSKMKEHECV--------
--DWINGLSGIMALMVEI----SRIFAIPKVDVIIEELQAELLIRL--------------
---------KDMQSEKQS-------------------IGFAHGYSGIAYALSKVDQKNKS
----D-----KNEK----IIIDLLEKEYG-------------------------LINNQK
DQRW-CWGIPGMLKARL---EMDKARS---------NEV--IAFQKNALVDL-----FLN
NIEEYSV---------QDD----TLCHGNSGILSIL-VKLKN-YELNTNQIEVINCYLNK
YSLMIVENQLISD--------NFSLLALP-----QIEPVGLF--TGISGIG-LSLLE---
TSFDVS----SDIQMLLS-----------------------------------------
>NZ_ABDV01000024.1|c1|5080-8073|-|ZP_02636763.1|putative_CylM_protein
---------------------------------------------------------MNK
LIEKARTIEEKRKEYS------------------------------KKSVIDYSYFKEWR
N--------------------VRTLLNDKYLEIMLKEMNLSKEEFSYLLQ----------
-----------PINMTVEIDEDNWYNNFKKII----------------DSFDYEKIDYKV
GVNLATLPFSKYLNREIKKVINQL---------------NEVKVSKEVVDSFVEAHV-VE
MFNIIGRIIALK--LE-------EYKQTHS-----F----ISKNN--KKR--FEEFLKST
FFSKESFLKFFEEYPVAARVATVRTMYLKKNFCDILQNIENDHKEIKNFL----M-----
-----------IDSLNLTKIKLSNG--DSHQQGNSVSILEF----HD-------KKLVYK
PKNLKICKSFEKFIDWYTN----------SSELLPI-SIPKGIYKDEYTYNEFII--PKF
CKNEK-EVENFYIRYGYLIALCYLLNLNDLHLENV-IAHGEYPVIIDIETCFQASV----
---EMQNNSIYVDLLRYLEVDSVSNSFLLPKQISIGSDD-----NIDLSALNGKE--VKL
SKTFLAPQEV-NTDKFH-YENVPGYFAGA----DNIPKL-SDNEEVE-----VKKYRLKI
LEGFDDFI-SF--IMANKNECI---DILEVFRG-QKIRLLTKGTEKYASMIRYASHPNYN
RE---MKYRER-LMMNLW--------AYPYLDKRII-KSEVNDLLFNDIPIFYSYTDSKN
LID---SKGF--LYKD---FHKLSGFELSVNKI-KGLSEKEIRMQRSIILNEL-------
------GLSDSYLNQKVTKRKL-NFDIQKFD--YLKQAKKIANKLINDAFK--------K
YNKCSFINL---DC---NEKNKWKYIP--SDESLYSGLSGISVLFLELYIRTEEKIYFKY
-----------YQML------IH--TAIEQAKNTG----------FESAF--TGWLSPV-
YPLILEYKYLNTI--------SDNEFLKFTIKKLES----LKIDDIKKASKA--------
--DYISGISGIVRLLSLI-----QMTFGD--NYISKDVIKIFSKTL--------------
--------LDKIENGKEKAMEN---------------VGIAHGISGVMLGLGSSGIVSPE
----------FIKT----YLLKEFQMKIP----------------------------KKD
TYKW-CWGLSGMIQARLQLLKINNLSV---------DKK-----QLEELIEN------FE
KSISLIL---------DED----SLCHGNGSIITTL-KMIYD---YTNQE--KWKSLLQL
WMSNLTMNSLFDC---------YKISKIG-----DMQTKGIF--DGISGIG-WLYLY---
ASSP------ISNLLLLETK---------------------------------------
>AF026468.1|c1|1-453|+|AAD01805.1|MutM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------TDR----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
SANW-CHGSTGALTSRLLWFKLNKKFN----ILNEHDIQ-----RVYLEIDH-----SVN
DIIDKGL-------SINNF----SLCHGIMGNLIAL-NEYSL---AFSNQ--KIQQLVQS
TLISLCSVGMKKD---------WLCGVND-----LFYNNGLM--TGLAGIL-YGIIK---
IYYDDNYDQHVLNLSFY------------------------------------------
>NZ_ACMJ01000159.1|c1|16981-19563|-|ZP_04231453.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MFDLE-KR
LYQVLRPSLIVY--IN-------KLRVEKA-----L----IGIDT--NEE--YKYFTNNF
FHFKKFHMNFFRMLPLLSEKIFTIIENEINYIIWLQGALEKDQKEIHKMS----G-----
------------FNIMHVEKVINLG--DYHNNGRRTILLEDK---FN-------NKVILK
PVDLTNSILYHSLINQLNK-----------DLNTDI-FIPQVVNKNNYGYMEYIN--HES
CESNE-QIKGYYYNLGVVLSVIYLINGSDIHNENI-IAKQTSPVIIDFETLGSTLN----
-------PSITEKTSSFKLSNSVLNSRMLPIRFSEGREV-----IRDYSAIGRV---MKT
LVKKIKIKNEFTSNPIE-IREETIVEDTV----QNLP-F-FYDDIYE-----YDNYIKDI
IKGFEDAY-NG--ALKNKEEYM---HILKSSVSKWNYRKVYRNTKIYTLLLDRLNVPDLL
EN---KLKTIK-YLRNIL-----EKNTYLATRKDII-QKEIEALLSYDVPYFSNKYEWES
CET-----------------FSNNEIDLEMKF--EKISYADFLLQRKIIEMSL-------
----SNQNDNLDQLNTVKETIN-FQTNLSTN----KIKEALTGKILDGSYI-------SK
DGDVDFIGL--------KTNWQGELEINHLNNGIYDGLLGISSLLRNNADPNHIEI-INK
-------LE--QKAL----------QEILNKNKNN-----------YGFV--NGSNAIIS
YYL----TNLPYI-----------TPLNEKVILQIF----MDINSDIEKDEYKDNTF---
--DILGGSAGLILTAVKF----YQIN-PK--YKILLKVAENLGDYI--------------
---------VNNMQTHNEFVYWKAHDTLNLEDSL---KGFVHGLSGQLLAFYKLKDILKT
----N-----KYDR----VIHCIHKSEKM------------------------SMNEYNY
TDSW-CKGFSGMGISRI---KILELYQ---------NED------IQSDLIF-----FKN
QILSTLY-------ENSDY----CLCHGLMGKLDFL-LELENRGMLERNE----KQIVMK
VTNNFLNNFAIEDF--------------------NPHKIALF--TGLGSIL-YFLQR---
LENDK-----LNSILYFNA----------------------------------------
>NZ_ACLV01000112.1|c1|44767-47592|-|ZP_04309311.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MKNNSREILN----------
------TIDNVSSLVTKEDLEKNFIIFLEDFS-----------------CNDVIKNDENY
NFQKIIQTYVAFF---KNMIINKI---------------DFFGNVERISESIMLDLE-KR
LYQVLRPSLIVY--IN-------KLRVEKA-----L----IGMDI--NEE--YKYFTRNF
FHFKKIHVNFFKMLPLLNEKIFTIIENEINYLMWLQGALKKDQKEIHKMS----G-----
------------FNIMHLEKVTNLG--DYHNNGKRTILLEDK---FN-------HKIILK
PVDLKNSILYHSLINQLNK-----------DLNTDI-FIPQVVNKKNYGYMEFIN--HES
CESNE-QIKDYYYNLGVVLSVIYLINGSDIHNENI-IAQGSSPVIIDFETLGSTLN----
-------PSIAEENSSFILSNSVLNSRMLPIRFSGGREV-----IRDYSAIGRV---MKT
LVKTIKIKNEFTSNPIE-IREETIIEDTV----QNLP-F-FNNDIYE-----YDNYINDI
IKGFEDAY-NS--VLKNKEEYM---YILKNSISKWNYRKVYRNTKVYTLLLDRLNVPDLL
EN---KLKTIK-YLRNIL-----EKNTYLATRKDII-QKEIEALLSYDVPYFFNKYEWGA
CES-----------------LSSNEIDLEMKF--QKISYADFLLQRKIIEISL-------
----SNQNDNLYKLNSVKETIN-FQTKLPTN----KIKEAITGKILDGSYI-------SK
GGDVDFIGL--------KTNWQGELEINHLNSGIYDGLLGISSLLRNNADPNYIEF-INK
-------LE--QKAL----------LEILTKNKNN-----------YGFV--NGVNAIVS
YYL----TNLPHI-----------TSLNEKVILQIF----MSINSDIEKGGYNDKHF---
--DILGGSAGLVLTAVKF----YQVN-PK--YKILLEVAENLGDYI--------------
---------VNNMQTDNEFVYWKAHDTLNLEDSL---KGFVHGLSGQLLAFYKLKDILKT
----N-----KYDR----VIHGIHKSEKM------------------------STSKYEY
TDSW-CKGFSGMGISRI---KILESYQ---------NED------IQSDLIF-----FKN
QILSTLN-------ENSDY----CLCHGLMGKLDFL-LELENRGMLERNE----KQIVMK
VTNNFLNNFDIEDF--------------------NPHKISLF--TGLGSIL-YFLQR---
LENNK-----LNSILYFNA----------------------------------------
>NZ_ACNK01000068.1|c1|23422-26250|-|ZP_04072861.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MKNNSHGILN----------
-----TIDNGSHSLVTKEYLEKNFVIFLEGFS-----------------CNDVIKKDESY
NFQKIIQTYVVFL---KNMIINKV---------------DFFGNVEGVSESIMFDLE-KR
LYQVLRPSLIVY--IN-------KLRVENA-----L----VGMDT--NEE--YKYFTKNF
FHLKKFYMNFFKMLPLLNEKIFTIIKNEMNYMIWLQGALEKDQKEIHKIS----G-----
------------FNIMHVEKVINLG--DYHNNGKRTILLEDK---FN-------NKVILK
PVDLKNSIIYHSVINQLNK-----------DLNTDI-FIPQVVNKKNYGYMEYIN--HES
CESNE-QIKDYYYNLGVVLSVIYLINGSDIHNENI-IAKQFSPVIIDFETLGSTLN----
-------SSITEETSSFILSNSVLNSGMLPIKFSGGREV-----IRDYSAIGRV---MKK
LVKTIKIQNEFTSNPIE-IKEETIVEDTA----RNLP-F-FNGGIYE-----YDNYIKDI
IKGFGDAY-NT--VLKSKEEYM---YILKNSVSKWNYRKVYRNTKVYSLLLDRLNVPDLL
ES---KLKTVK-YLQNIL-----GKNIYLATRKDII-QKEIEELLSYDVPYFFNKYEWGS
CES-----------------LSCNEIDLEMKF--KKISYADFLLQRKIIEISL-------
----SNQSDNLYKLNTVKETIN-VQTNSPTN----KIKEAITGKILDGSYI-------SK
DGDVDFIGL--------KTNWQGELEINHLNNGIYDGLLGINSLLRNNADPNHIEI-INK
-------LE--QKAL----------QEILNKNKNN-----------YGFV--NGVNAIVS
YYL----TNLPHI-----------TSLNEKVILQIF----MDINTDINEGKYNDRHF---
--DILGGSAGLILTAVKF----YQVN-PK--YKILLKVAENLGDYI--------------
---------VNNMQTHDEFVYWKAHDTLNLEDSL---KGFVHGLSGQLLAFYKLKDILKT
----N-----KYDR----VIHGIHKSEKM------------------------SMSEYEY
TDSW-CKGFSGMGISRI---KILESYQ---------NEE------IQSDLIF-----FKN
QILSTLH-------ENSDY----CLCHGLMGKLDFL-LELENRGMLERNE----KQIVMK
VTNNFLNNFDIEDF--------------------NPHKIALF--TGLGSVL-YFLQR---
LENNK-----LNSILYFNA----------------------------------------
>NZ_ACNF01000196.1|c1|3954-6779|+|ZP_04105813.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MKNNSHGILN----------
------TIDNGASLVTKEDLEKNFGIFLEGFS-----------------FNDIIKNDENY
NFQKIIQTYVVFS---KNMIKNKI---------------DFFGNVERISESIMFDLE-RR
LYQVLRPSLIVY--IN-------KLRVENV-----L----IGMDS--GEE--YKYFTKNF
FHFKRFYINFFKILPLLNEKIFKIIENEINYMIWLQGTLEKDQKEIHKMS----T-----
------------FNVMHVEKVTNLG--DYHNNGKRTILLEDK---FN-------NKVILK
PVDLKNSILYHSLINQLNK-----------DLNTNI-FIPQVVNKRNYGYMEYIN--HES
CESTE-QIKDYYYNLGVVLSVMYLINGSDIHNENI-IAKQSSPVIIDFETLGSTLN----
-------PSITEETSSFILSNSVLNSRMLPIKFSGGREV-----IRDYSAIGRV---MQN
LVKTIKIKNEFTSNPIE-IKEETIVEDTV----QNLP-F-FNGDIYE-----YDNYIKDI
IKGFEDAY-NT--VLKNKKEYV---YILKNSVSKWNYRKVYRNTKVYSLLLDRLNVPDLL
EN---KSKTIK-YLKNIL-----EKNIYLATRKDII-QKEIEALLSYDVPYFFNKYEWGS
YES-----------------LSSNEIDLEMKF--KKISYADFLLQRKIIEISL-------
----SNQNDNLYKLNTVKETIN-FQTNLPTN----KIREAITEKILDGCYI-------SK
NGDVDFIGL--------KTNWQGELEINHLNNGIYDGVLGISTLLRNNADPNHIEI-INK
-------LE--QKAL----------QEILNRNKNN-----------YGFV--NGVNAIIS
YYL----TNSPYK-----------TYIDEKVVLQIF----MDINSDIEKGRYNDKHF---
--DILGGSAGLVLTAVKF----YQVN-PK--YKILLKVAENLGDYI--------------
---------VNNMQTNDEFLYWKAHDTLNLEDSL---KGFVHGLSGQLLALYKLKDILKT
----N-----KYDR----VIHGIHKSEKV------------------------SMSEYEY
TDSW-CKGFSGMGISRI---KILESYQ---------NED------IQSDLIF-----FKN
QILSKLH-------VNSDY----CLCHGLMGKLDFL-LELENRGMLEQNE----KQIVMK
VTNNFLNNFDIEDY--------------------NPHKIALF--TGLGSIL-YFLQR---
LENNK-----LNSILYFNA----------------------------------------
>NZ_ACMO01000092.1|c1|12765-15590|-|ZP_04204173.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MKNNSHGILN----------
------TIDNGPSLVTKEDLEKNFGIFLEGFS-----------------CNDIIKNDENY
NFQKIIQTYVVFF---KTMIKNKI---------------DFFGNVERISESIMFDLE-RR
LYQVLRPSLIVY--IN-------KLRVENV-----L----IGMDS--GEE--YKYFTKNF
FHFKRFYIKFFEILPLLNEKIFTIIENEINYMIWLQGALEKDQKEIHKMS----A-----
------------FNIMHVEKVTNLG--DYHNNGKRTILLEDK---FN-------NKVILK
PVDLKNSILYHSLINQLNK-----------DLNTNI-FIPQVVNKRNYGYMEYIN--HES
CESTE-QIKDYYYNLGVVLSVMYLINGSDIHNENI-IAKQSSPVIIDFETLGSTLN----
-------PSMTEETSSFILSNSVLNSRMLPIKFSGGREV-----IRDYSAIGRV---MKN
LVKTIKIKNEFTSNPIE-IKEETIVEDKV----QNLP-F-FNGDIYE-----YDNYIKDI
IKGFDDAY-NT--VLKNKKEYV---YILKNSVSKWNYRKVYRNTKIYSLLLDRLNVPDLL
EN---KSKTIK-YLKNIL-----EKNVYLATRKDII-QKEIEALLSYDVPYFFNKYEWGG
YES-----------------LSSNEIDLEIKF--KKISYADFLLQRKIIEISL-------
----SNQNDNLYKLNTVKETIN-FQTNLPTN----KIKEAITEKILDGCYI-------LK
DGDVDFIGL--------KTNWQGELEINHLNNGIYDGVLGISTLLRNNADPNHIEI-INK
-------LE--QKAL----------QEILNRNKNN-----------YGFV--NGVNAIIS
YYL----TTLPHI-----------TSLNEKVILQIF----MDINSDIEKGQYNDKHY---
--DILGGSAGLILTAVKF----YQVNPK---YKILLEVAENLGDYI--------------
---------VNNMQTHNEFVYWKAHDTLNLEDSL---KGFVHGLSGQLLAFYKLKDILKT
----N-----KYDR----VIHGIHKSEKM------------------------SISEYEY
TDSW-CKGFSGMGISRI---KILESYQ---------NED------IQSDLIF-----FKN
QILSTLH-------VNSDY----CLCHGLMGKLDFL-LELENRGMLERNE----KQIVMK
VTNNFLNNFDIEDF--------------------NPYKIALF--TGLGSIL-YFLQR---
LENNK-----LNSILYFNA----------------------------------------
>NC_010612.1|c6|1112418-1115708|-|YP_001849230.1|lantibiotic_modifying_enzyme
----------------------------------MGDGVGDEWVDGSVAARHDRHALREW
LVVHAATIDELLSTRFEALPGRK-----------------------ADTDAAARRLAAWC
R--------------------SSASGDWAQFESRLARDGWDFASVLARFA----------
-----NARHTRSLPLPAWVADAMWSRASLCGS----------PGRATTTGSPEPEPTPPS
QFDALLLPLVDEA---QARLWSTT------------DAAATAILSDSARAGIRRSLL-QQ
LSDLCAPALYAL--FD-------SVRELATPDDAHA----QPRPD--SGVALYQRFVAE-
-MKAAGLSRLLEAKPVLWRLIATITRQWIDTTRELIERLAADLPSIRAGL----L-----
---------AGAPETRVAGIDGGLS--DPHNGGRSVRIVVFE---NG-------ARVVYK
PKDLRVDAALHALVGRLNR----------AAPPLAL-RAVRTIGREGYGWCEFIE--HAS
CADEE-GLELYFRRAGAWLALLHCLAATDMHHENF-IAHGDYPMPLDIETILQAST---Q
DPDDRDREGRAHQAACNLIADSVMAVGLIPSYRSSGVNGR--------SAVGGLIA-NDN
TTPTIRWEHV-NTDAMR-PNKAARPATSM----PNLPH--VNGHYAK-----FSDYVDAF
ITGFVSYA-KF--LVRQGAD-AGAGGLFQEFAG-LPVRRVWRPTTFYTMLLQQLTDHRTM
HDGVAWSAQAD-FVARLA-----DWNQDSDPRWPLL-QAERSALLSLNVPYFFMASDGVE
AHD---FAGVSFRCAG------MSGLERASARV-QDLDDRQIDWQVTVIRHNT-------
ETYAGQARSPGTAGPAPQPPQPDGGAWRPAEADFSAEADRIAGELALHAIR--------R
DAGAAWIGL-----DWSGDSDAAQLVC--LGAGLYNGVSGIGLFLAAHAAGSGCQR-SAE
-------LA--RAGV----AHVC--TELTGRNAPR-------VARSLGISGGSGLGSIA-
YAL----AVMAKC-------LEDDELLAHAHRAALL----VTDDLIETDRQL--------
--DVVGGSAGAILGLLRV----YRDTG----SGDVLARAIRCGEHL--------------
--------LRQPRVGPHGRRTWHRQVPGSCDL-----NGMAHGAAGYAYALGSLATATGH
----E-----EFAQ----YAAECLAFENA-SYDRQRGGWP----------ALDVDGGKGW
PAQW-CHGAPGIGLGRI---GLARRGW---------AQP------LSADIAN-----AVT
SVRQSWA-------EQQLD----TLCCGALGSIELL-SEAAT---TLDQP--DLQGLAAR
CLSDIVSAATQRG--------DYRWNSGD-----QAFNPGLF--RGIAGIG-YAALR---
RINRS-----LPNVLLWE-----------------------------------------
>NZ_ACBV01000040.1|c1|1-2052|+|ZP_04749211.1|lantibiotic_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------TM-------------
---------------------------------------------------------AEP
ADPDP-------------------------------------------------------
-------ESQAFRDALTLIADSAMSVGLLPSYERSPDNK-----IYASGGLVS----NWN
VKAPIRWTDI-NTDDMR-PTRSTEAGKTT----PNLP-Y-LGGRYAR-----FIDHLETF
VAGFRTYA-RF--LARWQIDTT-TGGLLDGFAG-LPVRTVARPTKFYAMLLARLHDHRSM
DDGALWSAQAD-FVARLA-----DWDKDDDPRWPLL-QAERSALITLNVPFFLSASDGAD
IRD---RTGT--CIRP----NGASGLQRASARV-RGLDSGEIDWQVTVIRQNM-------
ASFVKMAALTADSGDPAPNSGENIADIAPTREMFVAEADRAAAELVRYAVR--------R
GPSAAWIAL---DWS--SDSDTFQLIC--LGHDLYNGVSGIALFLAAHAAVTGSAP-SSE
-------LA--LAAV----AHLR--KEFRGGNAAP-----AARALGLGGG--SGLGSIV-
YAL----AVMSKC-------LRDDALLA-DAHMVAA----LITDDLISADRQL-------
--DVMGGSAGAILGLLRL----YRDTR----CGDVLARAARCGEHL--------------
--------LGERRVGPQGRRSWSRPDSGKAL------NGISHGAAGFAYALAALAAATGR
----E-----DFAL----AASECVAFENS-SYDPGRHNWP----------DLRGDEDMRW
PSQW-CHGAPGIGLARI---AMARLPG--------ADTA-----VLTADIRN-----AAV
AVESQWS-------VQLRD----TLCCGALGSVEFL-SQAGI---ALDQN--DLRELAAR
RLAGVISAAGERG------DYRWTAGNSR-------FNPGMF--RGLAGVG-YTALR---
QVDDS-----LPNVLVWE-----------------------------------------
>NZ_GG692840.1|c1|202659-205640|+|ZP_05424172.1|clyM_protein
---------------------------------------------------------MED
NLINVLSINERCFLLKQS----------------------------GNEKYDIKNLQAWK
E--------------------RKSVLKQDDLDYLIKYKYESLDNFGLGIT----------
----PIENFPDKEVAIQYIKDQSWYIFFESIL------------DSYNDSEEQLLEVDAS
YPFRYFLQYARLF---LLDLNSEL-----------------NICTKEFIINLLENLT-QE
LIHLTSKTLVLD--LH-------TFKKNEP-----L----KGNDS--SKR--FIYYLKKR
FNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCF----N-----
-----------IQSSELNSISESQG--DSHSRGNTVSTLTFS---DG-------KKIVYK
PK-INSENKLSDFFEFLNK-----------ELEADI-YTVKKVTRNTYFYEEYID--NIE
INNTE-EVKKYYERYGKLIGIAFLFNVTDLHYENI-IAHGEYPVIIDNETFFQQNI----
---PIEFGNSATVDAKYKYLDSIMVTGLVPYLAMKDKSDSKDE-GVNLSALNFKE--QSV
PFKILKIKNT-FTDEMR-FEYQTHIMDTA----KNTP-I-MNNEKIS-----FISYEKYI
VTGMKSIL-MK--AKDSKKKIL--AYINNNLQN-LIVRNVIRPTQRYADMLEFSYHPNCF
SN---AIEREK-VLHNMW--------AYPYKNKKVV-HYEFSDLIDGDIPIFYNNISKTS
LIA---SDGY--LVED---FYQESALNRCLNKI-NDLCDEDISIQTVWLEIAL-------
NIYNPYKYINDLKNQNSNKYIY-TGSELNSK--IIQACQKIEKKIFKRAIF----N--KK
TNTVNWIDI--------KLDQDWNVGI--LNNNMYDGLPGIFVFYVALKYITKNHK-YDY
-------VI----------ECIK--NSIYTIPSED----------ILSAF--FGKGSLI-
YPL----LVDYRL-------NNDINSLN-VAVEIAD----MLIEKKSINNGELKN-----
--DWIHGHNSIIKVLLLL----SEITEDEKYRKFSLEIFEKLSEEP--------------
--------YFNF-------------------------RGFGHGIYSYVHLLSKFNRIDKA
----N-----SLLH----KIKESYFEEEP------------------------------K
NNSW-CKGTVGELLATI------ELY----------DDN-----ISNIDINK-----TIA
YK--------------NKD----CLCHGNAGTLEGL-IQLAK----KDPE--TYQYKKNK
LISYMLNDFEKNN--------TLKVAGSE-----YLESLGFF--VGISGVG-YELLR---
NLDSE-----IPNALLFEL----------------------------------------
>NZ_GG670360.1|c1|1940-4921|+|ZP_05423864.1|clyM_protein
---------------------------------------------------------MED
NLINVLSINERCFLLKQS----------------------------GNEKYDIKNLQAWK
E--------------------RKSVLKQDDLDYLIKYKYESLDNFGLGIT----------
----PIENFPDKEVAIKYIKDQSWYIFFESIL------------DSYNDSEEQLLEVDAS
YPFRYFLQYARLF---LLDLNSEL-----------------NICTKEFIINLLETLT-QE
LIHLTSKTLVLD--LH-------TFKKNEP-----L----KGNDS--SKR--FIYYLKKR
FNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCF----N-----
-----------IQSSELNSISESQG--DSHSRGKTVSTLTFS---DG-------KKIVYK
PK-INSENKLRDFFEFLNK-----------ELEADI-YIVKKVTRNTYFYEEYID--NIE
INNTE-EVKKYYERYGKLIGIAFLFNVTDLHYENI-IAHGEYPVIIDNETFFQQNI----
---PIEFGNSATVDAKYKYLDSIMVTGLVPYLAMKDKSDSKDE-GVNLSALNFKE--QSV
PFKILKIKNT-FTDEMR-FEYQTHIMDTA----KNTP-I-MNNEKIS-----FISYEKYI
VTGMKSIL-MK--AKDSKKKIL--AYINNNLQN-LIVRNVIRPTQRYADMLEFSYHPNCF
SN---AIEREK-VLHNMW--------AYPYKNKKVV-HYEFSDLIDGDIPIFYNNISKTS
LIA---SDGC--LVED---FYQESALNRCLNKI-NDLCDEDISIQTVWLEIAL-------
NIYNPYKYINDLKNQNSNKYIY-TGLELNSK--IIQACQKIEKKIFKRAIF----N--KK
TNTVNWIDI--------KLDQDWNVGI--LNNNMYDGLPGIFIFYVALKYITKNHK-YDY
-------VI----------ECIK--NSIYTIPSED----------ILSAF--FGKGSLI-
YPL----LVDYRL-------NNDINSLN-IAVEIAD----MLIEKKPIDNGELKN-----
--DWIHGHNSIIKVLLLL----SEITEDEKYRKFSLEIFEKLSEEP--------------
--------YFNF-------------------------RGFGHGIYSYVHLLSKFNRIDKA
----N-----SLLH----KIKESYFEEEP------------------------------K
NNSW-CKGTVGELLATI------ELY----------DDN-----ISNIDINK-----TIA
YK--------------NKD----CLCHGNAGTLEGL-IQLAK----KDPE--TYQYKKNK
LISYMLNDFEKNN--------TLKVAGSE-----YLESLGFF--VGISGVG-YELLR---
NLDSE-----IPNALLFEL----------------------------------------
>NC_004668.1|c1|485112-488093|+|NP_814304.1|cylM_protein
---------------------------------------------------------MED
NLINVLSINERCFLLKQS----------------------------GKEKYDIKNLQAWK
E--------------------RKSVLKQDDLDYLIKYKYESLDNFGLGIT----------
----PIENFPDKEVAIQYIKDQSWYIFFESIL------------DSYNDSEEKLLEVDAS
YPFRYFLQYARLF---LLDLNSEL-----------------NICTKEFIINLLETLT-QE
LIHLTSKTLVLD--LH-------TFKKNEP-----L----KGNDS--SKR--FIYYLKKR
FNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCF----N-----
-----------IQSSELNSISESQG--DSHSRGKTVSTLTFS---DG-------KKIVYK
PK-INSENKLRDFFEFLNK-----------ELEADI-YIVKKVTRNTYFYEEYID--NIE
INNIE-EVKKYYERYGKLIGIAFLFNVTDLHYENI-IAHGEYPVIIDNETFFQQNI----
---PIEFGNSATVDAKYKYLDSIMVTGLVPYLAMKDKSDSKDE-GVNLSALNFKE--QSV
PFKILKIKNT-FTDEMR-FEYQTHIMDTA----KNTP-I-MNNEKIS-----FISYEKYI
VTGMKSIL-MK--AKDSKKKIL--AYINNNLQN-LIVRNVIRPTQRYADMLEFSYHPNCF
SN---AIEREK-VLHNMW--------AYPYKNKKVV-HYEFSDLIDGDIPIFYNNISKTS
LIA---SDGC--LVED---FYQESALNRCLNKI-NDLCDEDISIQTVWLEIAL-------
NIYNPYKYINDLKNQNSNKYIY-TGLELNGK--IIQACQKIEKKIFKRAIF----N--KK
TNTVNWIDI--------KLDQDWNVGI--LNNNMYDGLPGIFIFYVALKYITKNHK-YDY
-------VI----------ECIK--NSIYTIPSED----------ILSAF--FGKGSLI-
YPL----LVDYRL-------NNDINSLN-VAVEIAD----MLIEKKPINNGELKN-----
--DWIHGHNSIIKVLLLL----SEITEDEKYRKFSLEIFEKLSEEP--------------
--------YFNF-------------------------RGFGHGIYSYVHLLSKFNRIDKA
----N-----SLLH----KIKESYFEEEP------------------------------K
NNSW-CKGTVGELLATI------ELY----------DDN-----ISNIDINK-----TIA
YK--------------NKD----CLCHGNAGTLEGL-IQLAK----KDPE--TYQYKKNK
LISYMLNDFEKNN--------TLKVAGSE-----YLESLGFF--VGISGVG-YELLR---
NLDSE-----IPNALLFEL----------------------------------------
>NZ_GG692897.1|c1|20378-23359|+|ZP_05563604.1|clyM
---------------------------------------------------------MED
NLINVLSINERCFLLKQS----------------------------GNEKYDIKNLQAWK
E--------------------RKSVLKQDDLDYLIKYKYESLDNFGLGIT----------
----PIENFPDKEVAIQYIKDQSWYIFFESIL------------DSYNDSEEQLLEVDAS
YPFRYFLQYARLF---LLDLNSEL-----------------NICTKEFIINLLENLT-QE
LIHLTSKTLVLD--LH-------TFKKNEP-----L----KGNDS--SKR--FIYYLKKR
FNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCF----N-----
-----------IQSSELNSISESQG--DSHSRGKTVSTLTFS---DG-------KKIVYK
PK-INSENKLRDFFEFLNK-----------ELEADI-YIVKKVTRNTYFYEEYID--NIE
INNIE-EVKKYYERYGKLIGIAFLFNVTDLHYENI-IAHGEYPVIIDNETFFQQNI----
---PIEFGNSATVDAKYKYLDSIMVTGLVPYLAMKDKSDSKDE-GVNLSALNFKE--QSV
PFKILKIKNT-FTDEMR-FEYQTHIMDTA----KNTP-I-MNNEKIS-----FISYEKYI
VTGMKSIL-MK--AKDSKKKIL--AYINNNLQN-LIVRNVIRPTQRYADMLEFSYHPNCF
SN---AIEREK-VLHNMW--------AYPYKNKKVV-HYEFSDLIDGDIPIFYNNISKTS
LIA---SDGC--LVED---FYQESALNRCLNKI-NDLCDEDISIQTVWLEIAL-------
NIYNPYKYINDLKNQNSNKYIY-TGLELNSK--IIQACQKIEKKIFKRAIF----N--KK
TNTVNWIDI--------KLDQDWNVGI--LNNNMYDGLPGIFIFYVALKYITKNHK-YDY
-------VI----------ECIK--NSIYTIPSED----------ILSAF--FGKGSLI-
YPL----LVDYRL-------NNDINSLN-VAVEIAD----MLIEKKPINNGELKN-----
--DWIHGHNSIIKVLLLL----SEITEDEKYRKFSLEIFEKLSEEP--------------
--------YFNF-------------------------RGFGHGIYSYVHLLSKFNRIDKA
----N-----SLLH----KIKESYFEEEP------------------------------K
NNSW-CKGTVGELLATI------ELY----------DDN-----ISNIDINK-----TIE
YK--------------NKD----CLCHGNAGTLEGL-IQLAK------KDPGTYQYKKNK
LISYMLNDFEKNN--------TLKVAGSE-----YLESLGFF--VGISGVG-YELLR---
NLDSE-----IPNALLFEL----------------------------------------
>NZ_GG692921.1|c1|7873-10854|-|ZP_05564412.1|clyM
---------------------------------------------------------MED
NLINVLSINERCFLLKQS----------------------------GNEKYDIKNLQAWK
E--------------------RKSVLKQDDLDYLIKYKYESLDNFGLGIT----------
----PIENFPDKEVAIQYIKDQSWYIFFESIL------------DSYNDSEEQLLEVDAS
YPFRYFLQYARLF---LLDLNSEL-----------------NICTKEFIINLLETLT-QE
LIHLTSKTLVLD--LH-------TFKKNEP-----L----KGNDS--SKR--FIYYLKKR
FNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCF----N-----
-----------IQSSELNSISESQG--DSHSRGKTVSTLTFS---DG-------KKIVYK
PK-INSENKLRDFFEFLNK-----------ELEADI-YIVKKVTRNTYFYEEYID--NKE
INNIE-EVKKYYERYGKLIGIAFLFNVTDLHYENI-IAHGEYPVIIDSETFFQQNI----
---PIEFGNSATVDAKYKYLDSIMVTGLVPYLAMKDKSDSKDE-GVNLSALNFKE--QSV
PFKILKIKNT-FTDEMR-FEYQTHIMDTA----KNTP-I-MNNEKIS-----FISYEKYI
VTGMKSIL-MK--AKDSKKKIL--AYINNNLQN-LIVRNVIRPTQRYADMLEFSYHPNCF
SN---AIEREK-VLHNMW--------AYPYKNKKVV-HYEFSDLIDGDIPIFYNNISKTS
LIA---SDGC--LVED---FYQESALNRCLNKI-NDLCDEDISIQTVWLEIAL-------
NIYNPYKYINDLKNQNSNKYIY-TGLELNSK--IIQACQKIEKKIFKRAIF----N--KK
TNTVNWIDI--------KLDQDWNVGI--LNNNMYDGLPGIFIFYVALKYITKNHK-YDY
-------VI----------ECIK--NSIYTIPSED----------ILSAF--FGKGSLI-
YPL----LVDYRL-------NNDINSLN-VAVEIAD----MLIEKKPINNGELKN-----
--DWIHGHNSIIKVLLLL----SEITEDEKYRKFSLEIFEKLSEEP--------------
--------YFNF-------------------------RGFGHGIYSYVHLLSKFNRIDKA
----N-----SLLH----KIKESYFEEEP------------------------------K
NNSW-CKGTVGELLATI------ELY----------DDN-----ISNIDINK-----TIE
YK--------------NKD----CLCHGNAGTLEGL-IQLAK----KDPE--TYQYKKNK
LISYMLNDFEKNN--------TLKVAGSE-----YLESLGFF--VGISGVG-YELLR---
NLDSE-----IPNALLFEL----------------------------------------
>NZ_GG688435.1|c1|47376-50357|+|ZP_05600068.1|clyM_protein
---------------------------------------------------------MED
NLINVLSINERCFLLKQS----------------------------GNEKYDIKNLQAWK
E--------------------RKSVLKQDDLDYLIKYKYESLDNFGLGIT----------
----PIENFPDKEVAIQYIKDQSWYIFFESIL------------DSYNDSEEQLLEVDAS
YPFRYFLQYARLF---LLDLNSEL-----------------NICTKEFIINLLETLT-QE
LIHLTSKTLVLD--LH-------TFKKNEP-----L----KGNDS--SKR--FIYYLKKR
FNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCF----N-----
-----------IQSSELNSISESQG--DSHSRGKTVSTLTFS---DG-------KKIVYK
PK-INSENKLRDFFEFLNK-----------ELEADI-YIVKKVTRNTYFYEEYID--NIE
INNIE-EVKKYYERYGKLIGIAFLFNVTDLHYENI-IAHGEYPVIIDSETFFQQNI----
---PIEFGNSATVDAKYKYLDSIMVTGLVPYLAMKDKSDSKDE-GVNLSALNFKE--QSV
PFKILKIKNT-FTDEMR-FEYQTHIMDTA----KNTP-I-MNNEKIS-----FISYEKYI
VTGMKSIL-MK--AKDSKKKIL--AYINNNLQN-LIVRNVIRPTQRYADMLEFSYHPNCF
SN---AIEREK-VLHNMW--------AYPYKNKKVV-HYEFSDLIDGDIPIFYNNISKTS
LIA---SDGC--LVED---FYQESALNRCLNKI-NDLCDEDISIQTVWLEIAL-------
NIYNPYKYINDLKNQNSNKYIY-TGLELNSK--IIQACQKIEKKIFKRAIF----N--KK
TNTVNWIDI--------KLDQDWNVGI--LNNNMYDGLPGIFIFYVALKYITKNHK-YDY
-------VI----------ECIK--NSIYTIPSED----------ILSAF--FGKGSLI-
YPL----LVDYRL-------NNDINSLN-VAVEIAD----MLIEKKPINNGELKN-----
--DWIHGHNSIIKVLLLL----SEITEDEKYRKFSLEIFEKLSEEP--------------
--------YFNF-------------------------RGFGHGIYSYVHLLSKFNRIDKA
----N-----SLLH----KIKESYFEEEP------------------------------K
NNSW-CKGTVGELLATI---ELY-------------DDN-----ISNIDINK-----TIE
YK--------------NKD----CLCHGNAGTLEGL-IQLAK----KDPE--TYQYKKNK
LISYMLNDFEKNN--------TLKVAGSE-----YLESLGFF--VGISGVG-YELLR---
NLDSE-----IPNALLFEL----------------------------------------
>AJ536588.1|c1|2059-5325|+|CAD60521.1|CinM_protein
--------------------------------------------------MGMGNAYPLD
IAARAANLTERLRVVAAAGGEAAV----------------------RDNTVELDAFDRWK
A---------------DTLAGKLADKFHQESLHRGRPPQHTKDELAGVLS-------AYR
RLELGLDTADDDVRTLLGELQSAWLPAYRAAL-----DAHDAARDDERADAQPGEEPGWR
GFDVYYGRLAKACEPFLRELGRGL------GAARDAAQGEGAALSPQLAEDIQRHLL-DR
FELSLAWAVEADANVH-------CTQAGID----------KAEAT--RED--YLAYLDTT
FSDSAAYHRFYLKFPVLGRWLAHTTALLTAFGRDLFDSLAADAEAIGTEF----F-----
----------GQPVTAFTSLRLGDS--DPHAGARTVARVAVVLADGR------TGEFFYK
PRSVRSEAALQDVLARLAD-----------DGVVDF-ATRPVLPRDGYGYEALIPAGRNR
VETPE-EVTRIYRELGGYLALFYVLGGSDLHFENV-IVADGHAFVCDAETVLGVHP----
---------QGRAQSEGTLLDSVFKTGLLEWPRAASPGEEAAA-EMRISGYAGGEG-YDV
PVPVARRTGE-GLTFAASVVHKTGVHVET----SASNRVYLGEELVR-----PEDHVESI
MEGFNRVY-DW--FAEDPDASV--DYLMETFSW-VTARFINWGTQIYAQLLSAARHPRCL
TE---PLEVDL-LANTVR------TFPRTWDAEGVLAGREVAAMWQMDVPLFTAAAHARQ
LVH---GHGD--PLSA---RLDSSPIDHAAARI-RRLSQRNREQQSQYIAASL-------
------------------STGEISSPAFVAT--SLDYAARIGDRLCDELRA--------P
AAPAPWTSY---QL---SGESLAEVD---IEADLYQGSAGVVLFLAYLDQLVPRPA-YRK
-------AA--RQAL----------DHVLVHWDRD----------RLGAF--AGLGGVV-
YLL----THLHRL-------WGDEELLD-LAVRLSD----ELPARIDEDRHF--------
--DILHGAAGLIPVLLGL----AQET-----GGHGIEHAHRCAEHL--------------
---------LRHAEDDGTTLSWPPSAADETYGNL---TGFSHGSGGIGWALIQLGRHTGR
----S-----DYIE----AGRKAFAYEDR-HVDEQEKDWY----DLRINNGSAVKGARHF
SNAW-CNGAAGIGLARI---SSWAALD--------RSDE-----QLLRDAQQ-----ALS
ATLRNFP-------RLKNH----TLCHGTSGNAELL-LRFAR---LSDEP--AFQLEANV
QVQALWRSLDEAG---------GGAGGGS-----ADFFPGLM--IGISGFG-MHFLR---
LAAPDR----VPSVLLLDPPSHHEQ----------------------------------
>NZ_ADGX01000154.1|c1|12446-15796|+|ZP_06416734.1|Lanthionine_synthetase_C_family_protein
----------------------------------------------MSPERALDTWFPLD
IACRASNLREQTLLVASLRSWQPP----------------------AGSPHGLSEVDRWK
V----------------------GSLADRLAAQHLKDSHPATTPHRPDRDELVGVLERFR
TWALHLGDADEESRKLLAGMHGSWLPNYRAAL----EASDPADGSWAQTRPRPPDGSARA
DVARACEPFLAHL---RRKLGRAL--------DSANRAGPAEAFAPEIADGVTAHFL-DR
FELALAWAVEAD--AN-------VWRARSG-----N----DHDGT--AGQ--HERYLSET
FAGPRAYHGFYLHFPVLGRWLAQVSGMLGDNGQSLIGRLQRDREAIGDVL----L-----
----------GDEILRFRSVRLGMS--DSHAGGQTVALVTADLARSG-----Q-GTFVYK
PRCVHSQAALQGLLERLAK-----------DGVAGF-ATYRTLERDGYGYEALIPSGRNH
AASPA-EVTAIYEEVGGYLGVFHALGGSDLHFENV-LVADGHAYVCDAETALDVLP----
---------RGATRAAGTVIDSVYRTGLLEWPLPPTAEV-----AMRMSGTSGGES-YSL
PFAVPRIRRR-ATTGLA-VRHETGVHVQA----DPANRVWLDGELVG-----PEAFRDAI
VSGFTAVH-DW--FASRPAKAA--RQVSELFDG-ASIRFVSRSTQIYGQLLVAARHPRCL
RE---PLEVDL-VIGRLR------EQAPQWDRDGVLTDREARSLWQLDIPIFTTDARGRL
LTA---DHAD--TLPV---QLRLSPVELAAQRI-RGLSAEDRLRQVQYIAASL-------
------------------SSSEVHSPAFVGS--ALDHSGLIGRELREMLGD--------G
SDPVPWKRY---EI---ADGRAGTAG---VQADLYHGSAGVALFLAYLDSVAPQEG-VRE
-------AA--ERAL----------RHALTHHDRH----------GIGAF--TGVSGLI-
YVL----THLHGL-------WKDATLLD-RAVELTA----LIDDGVRGDRTF--------
--DVLGGSAGAIPVLIGL----ADACGTG------LGQAQRCARHL--------------
---------LDHAERTRAGLSWAPLQPGDAAANL---TGFAHGAAGIGWALIMLGTRTGR
----E-----EYIE----AGMEAFRYEKS-HFDEAEQDWY----DLRASIITMYPGRRHF
TNVW-CAGAAGIGLSRI---SSWAALG--------RSDE-----GLLGEAYI-----ALR
ATLRNFQ-------GLGND----TLCHGRSGNAELL-LRFAR---LCEEPPFQLEANVQA
QGQWRRLAGDPA----------WLRRDGD-----VPAYPGLM--IGLAGTG-MHFLR---
LAHPDR----VPSPLLLDPPPLLPDHELKGAQPPCPPTPVPRSSTRPGADLSYSRPSER
>NZ_AAUA01000001.1|c1|627808-630984|+|ZP_01470939.1|hypothetical_protein
------------------------------------------------------------
--------------------------------------------------MRENWKQQWL
D--------------------IVAPDEPHKLSRRLDWDELTEEEFREHLS----------
-----------TSPTKANRFEGHWQNCLNECR-------LAIQKAWEQPLLPISPDNQQR
PFEDLWRPICNEA---REILKKRL--------------SRLDGVGEGIFEQLTNSLL-NR
LCSIGEQVLWEK--FN-------SERSPGVMLLAHLGSNGDGSGP--PVREGYEQFIRN-
-HRQDGLTQLLGEFPELGRLIGTIVLLWLEGSQEMLERIDQDRQTLETLF----------
---------GIPKNAPLQTIHQGLS--DPHRGGRAVAILGFAGPGEE------QYKLVYK
PKDMAVDAAYQDLLKDINR----------SSSDKPL-KILKIHNGEGYGYMEYVS--HKP
ARDDK-ELGFFYKNAGRLTAVLHLLGCTDCHHENL-IACGDQLLLIDTETLLEAEL--PN
HINNDTSEAPELSALQKRCQRSILRSGLMPQWMFLGSEKI----AIDISALGISPP-KQE
TQKTSGWLGLNSDGMMPGVIERNADLP------TSLP-I-GIGSPNP-----FSLHLDTF
CEGFREQN-QT--LIEQKDQWLKEGTFLNRFKG-LRRRIVLRATRVYFAIQRQQLEPAAL
RS---PLIQAI-KLEQLS--RSFLLAEQKPLHWPVF-AAELEQMQQLDIPFFTHQIDSDA
LDL----NQAQTQLPG---YIETSGLSAAKERL-EQLDTSEVEFQIKLIRGTC------N
AQKIRRGASVETSVHSAQENQYTTQTKSAAD--HQVAATNVMNCLADLAIE-------DN
SGQMEWLGM-----DLGADGESFSFGP--VGFSLYGGSSGVAILDHTLQRLNGTNSQLSA
-------IQ--SGVL----QSIQ--QLAEKASEDQ--RLRWWRDQSLGL---SGCGGML-
-------LTLQCL--------GQTSWAQSLLKSGRQ----RFLEADRQL-----------
--DLIGGCTGLIGPLLHL------------KSPEALDLAIHAGKHL--------------
------------LEQQQEDGSWPGRAKNTPGL-----LGFSHGTAGHAAALAKLHQATHD
----N-----RFLE----GAKAALHHERA-HFDSKEENWP---------DFRDITQSGSF
MTSW-CHGAPGIGIARACLWQTELWDE-----------------QCRDEIHA-----AIR
TTSKSIG-------QLRSD----HLCCGKAGLAIILEMLCDGPWGVEAHVADLARERTIQ
IHTSLMNRTSSKM-------PDLICFAAKET---SLVLPGFF--TGLSGIG-MALLR---
DDQSKQTTRRLLTAGLWTE----------------------------------------
>NC_008820.1|c3|1865532-1868738|+|YP_001018107.1|MrsD-like_protein
------------------------------------------------------------
------------------------------------------------MTSPTSWKTSWL
A--------------------AIAPDEPHKFDRRLEWDELSEENFFAALN----------
-----------SAPTSLEEDDPCFDEALQDAL--------EALKAAWDLPLLPVDNTVNR
PFVDLWWPIRCHS---AESLRQIF-------------VSDSAGLADEIFDQLADSLL-DR
LCALGDQVLWEA--FN-------KERTPGTMLLAHLGAAGDGSGP--PVREHYERFIQS-
-HRRNGLAPLLKEFPVLGRLIDTVLSLWFQGSVEMLQRICADRTVLQQGF----------
---------AIPCGHHLKTVKQGLS--DPHRGGRAVAVLEFA---DPNSTANSSMHVVYK
PKDMAVDAAYQATLADLNA----------HSDLSPL-RTLAIHNGDGYGYMEHVV--HHF
CANDK-ELTNFYFNAGRLTALLHLLGCTDCHHENL-IACGDQLLLIDTETLLEADLPDHI
SDASSTTAQPEPSTLQRQFQRSVLRSGLLPQWMFLGESKQ----AIDISALGISPP-NKP
ERIAAGWLGF-NSDGMM-PGRVSQPVEIP----TSLP---VGIADVN----PFDRFLEDF
CDGFSMQS-KA--LIKLRNRWLDLNGILAHFAG-LPRRIVLRATRVYFNIQRQQLEPTAL
RS---SLAQAL-KLEQLA--RSFLLAESKPLHWPIF-AAEVKQMQQLDIPFFTHLIDADA
LQL----GGLEQELPG---FIQTSGLAAAYERL-RNLDSNEIAFQLRLIHGAV-------
--EARELHTTPESSPTLHPPATPEALMSASAETSLKAAKRIAHRLLELAIR-------DS
QGQVEWLGM-----DLGADGESFAFGP--VGLSLYGGSIGISHLLQRLQAQQVPLMDADA
-------IQ--TAIL----QPLV--GLVAQPSDDG--RRRWWRDQPLGL---SGCGGTL-
LAL--------AL-------QGEQAMANSLLAAALP----RFIEADQQL-----------
--DLIGGCAGLIGSLVQL------------GTESALQWALRAGDHL--------------
------------IAQQNEEGAWSSSSSQPAL------LGFSHGVAGYAAALAHLHAFSGD
----E-----RYRI----AAAAALAYERA-RFNKDAGNWP----DYRSISRDSDSDEPSF
MASW-CHGAPGIALGRACLWGTALWDE-----------------ECTKEIGI-----GLQ
TTAAVSA--------VSTD----HLCCGSLGLMVLLEMLSKGPWPIDNQLRSHCQDVASQ
YRLQALQRCSAEP-------IKLRCFGTKEG---LLVLPGFF--TGLSGMG-LALLE---
-DDPSRAV--VSQLISAGLWPTE------------------------------------
>NC_005071.1|c1|280135-283341|-|NP_894083.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------MESPSSWKTSWL
A--------------------AIAPDEPHKFDRRLEWDELSEENFFAALN----------
-----------SEPASLEEDDPCFEEALQDAL--------EALKAAWDLPLLPVDNNLNR
PFVDVWWPIRCHS---AESLRQSF-------------VSDSAGLADEIFDQLADSLL-DR
LCALGDQVLWEA--FN-------KERTPGTMLLAHLGAAGDGSGP--PVREHYERFIQS-
-HRRNGLAPLLKEFPVLGRLIGTVLSLWFQGSVEMLQRICADRTVLQQCF----A-----
----------IPCGHHLKTVKQGLS--DPHRGGRAVAVLEFA---DPNSTANSSMHVVYK
PKDMAVDAAYQATLADLNT----------HSDLSPL-RTLAIHNGNGYGYMEHVV--HHL
CANDK-ELTNFYFNAGRLTALLHLLGCTDCHHENL-IACGDQLLLIDTETLLEADLPDHI
SDASSTTAQPKPSSLQKQFQRSVLRSGLLPQWMFLGESKL----AIDISALGMSPP-NKP
ERIALGWLGF-NSDGMM-PGRVSQPVEIP----TSLP-V-GIGEVNP-----FDRFLEDF
CDGFSMQS-EA--LIKLRNRWLDVNGVLAHFAG-LPRRIVLRATRVYFTIQRQQLEPTAL
RS---PLAQAL-KLEQLT--RSFLLAESKPLHWPIF-AAEVKQMQHLDIPFFTHLIDADA
LQL----GGLEQELPG---FIQTSGLAAAYERL-RNLDTDEIAFQLRLIRGAV-------
--EARELHTTPESSPTLPPPATPEALMSSSAETSLEAAKRIAHRLLELAIR-------DS
QGQVEWLGM---DLG--ADGESFSFGP--VGLSLYGGSIGIAHLLQRLQAQQVSLMDADA
-------IQ--TAIL----QPLV--GLVDQPSDDG--RRRWWRDQPLGL---SGCGGTL-
LAL--------TL-------QGEQAMANSLLAAALP----RFIEADQQL-----------
--DLIGGCAGLIGSLVQL------------GTESALQLALRAGDHL--------------
------------IAQQNEEGAWSSSSSQPGL------LGFSHGTAGYAAALAHLHAFSAD
----E-----RYRT----AAAAALAYERA-RFNKDAGNWP----DYRSIGRDSDSDEPSF
MASW-CHGAPGIALGRACLWGTALWDE-----------------ECTKEIGI-----GLQ
TTAAVSS--------VSTD----HLCCGSLGLMVLLEMLSAGPWPIDNQLRSHCQDVAFQ
YRLQALQRCSAEP-------IKLRCFGTKEG---LLVLPGFF--TGLSGMG-LALLE---
-DDPSRAV--VSQLISAGLWPTE------------------------------------
>NZ_ACBV01000040.1|c1|8690-11926|-|ZP_04749218.1|lanthionine_synthetase_C_family_protein
--------------------------------------------------MELSHAERLA
LVSRASSLRERITHTDAFDSA-------------------------GVSREAAARLKKWC
K--------------------IVADGDAGQFRRRLSLDSLDQESVRALLG----------
-----------DVARPEVFAMPTWTEVLDEVL---RAGAAGGIGTGGDREPPFLHADTPV
PFEDLLLPFLAVA---ENRLTEAA--------------SDYRTLPVQVRGSMEHSLL-QA
LSRISSRVLELE--FRTYL----ACRQLDG-----LPCPDPARAH--ESRTAYLEFVAD-
-IRRTGWRPLFAEYCVMARLMAVAVLQWVANSAEFLARLRADRADIGRIF----G-----
----------IANPGDLAAIKMDLS--DPHFGGKSVVAIEFA---TG-------EMLIYK
PKDLALEAAYFRFTTWLNT----------LGADPAF-PVLKMLERDGYGWVEFID--NRA
CECDD-QVRRFYRRSGALLCLLYAFNGTDFHFENL-IACGEYPVPVDLETIYSHPM----
----ATDDSELTDEVARRLGRSVLATHFLPNPVKGQHR------HYDISAIARSAD-EEG
EYEVLTWQHI-NTDGLG-YRYGRVKAKQG----DNLP-R-FEEQYLS-----PDSNVEEI
VDGFQSVY-RL--LTSHREQLLAPDSPFREIFT-YPARFILRSTMHYMSVLNSACHPDCL
RE---GIDFDI-QLDVLS--RPFLHDKRRLELWPLV-REEVAACWRTDVPKFTARGDSDS
LVL---PSGE--TAQA---CFTDSAFNQSQQNL-SHFGEDDLCWQVKLIRGSM-------
----DARDARRFIWYAPPAEYDDEQMEPLDRAQLVDQAVALGRGLERAAIR-------QA
NGEPGWLVL-----KSLPQGDEFALRA--MELELYNGRCGVALFFAALEKVAPDLG-FGE
-------SA--RAAL----AIVR--RWLAKADSHD------IASLGIGGL--LGFPSVA-
YAL----ARVGVL-------LDDGGLVEEAVGAARR----IGPEMVNGDKAF--------
--DVLGGGAGAILCLLAC----WRAGN----DPELLAIAEACGRHL--------------
--------LDARSPTASGHRTWATLAGKHL-------TGMSHGAAGIAYALAALFGATDE
----R-----EFLE----AAREAVRFEAS-EFSPEKNNWH---DRREVRYPGMTVDQPGF
GVFW-CHGAPGIGLARL---GGLPALD---------SPE------IRRDIAA-----ALA
TTRDCGL--------LPRD----HICCGNMGLVETL-LTAGQ---VLDDP--SWTREALQ
ISSRVVARAGRIG--------DFAITFRH-----GFRSPNLF--MGAAGVG-YELLR---
VAYPDD----LPAVLLLT-----------------------------------------
>NC_013161.1|c3|2024324-2027560|-|YP_003137732.1|Lanthionine_synthetase_C_family_protein
-----------------------------------------------MNTRKIRESDLLL
IVSRATFLSEKIQDAFKKKVNQQE----------------------FDQNLIDKRLKNWS
R----------------------AIGGGDNLKKRINWDELDLNFLGYVLG----------
-----------SVDVFNNSSLPFWAETLKNIL----ESNLPLFHPINAQNNLPIDSDNPL
AFEEFYLPFIEFN---RYQLYNRF-----------SKNIIQELLTQQAYYALERRLL-EQ
LVNLGTETLLFE--FD-------KFRQNNI-----VTNKSTTSET--PEKARYNTFIETL
LQDKG--LRFFQQYPVLARLLTTILHLWLEYTVEFLQRLQADLSLIELTF----G-----
---------ETKNLGKVKEINTSLS--DYYHQSYVLDLTFL----SG-------KKIVYK
PKNLAIDAAFYKFQDWCNQ----------QNITLPF-KVIKIINQEKYGWQEFVS--PEA
FGEEK-EVKNFYQRAGMVLSMIYVLGGKNCQNIDL-VAQGEFPIIIDADFLMSPLK----
---------KESDESENWFSNSVVKTGFLPSWEGDYLLTAN---AQDSSVLGGIF--PQQ
INSSREWKFI-NTDQMN-LINKTVVIPPK----NNVVV--FQEKTVY-----PNNYLEEI
ITGFEEIY-RL--LSKHKEKLLSKESPLLDFKV-SQSKLTLYPAVSYKILCKQSLNPQYL
RN---GIDFSL-LLEGAA--RTYLASEKKPYCWSIL-PAEIKALQQLTIPYFQISCDNDS
LDI---GLDK--PLEH---FFTTSSYQKLMTQL-KSLDEKDLALQIQLIRLSF-------
---YAKKVHLTQGNLKDLGTYCQFSPLTSEE--LLEEAVRMGNALVNNAIH--------H
GDNCNWIEL-----EYMYKANRYRLKA--LDNSLFLGRIGVSLFLAALAKITGKNQ-FKE
-------VA--LASI----FPLR--KAIKQGQLPL-----TLSERNLGI---IGYGGLL-
YSF----TKISRF-------LEESTLLEDGKKIVNF----ITKKAITKDHQL--------
--DIIFGAAGAILGLLAL----YQETE----DQQVLDTAIDCGNHL--------------
----------LSQRTETFPKAWLTVSQSKKPL-----TGFSHGVAGIVLSLLRLFSVTGN
----T-----AYLE----AAKEGIEYEKN-TLDLSRQNLP------DLALEQTQINSMTL
LYAW-CNGSAGIGLSRL---GSLPILQ---------LED------IDSEIKA-----ALK
TTQRYCQ-------EINQDID--SLCCGTFGRTELF-VVASQ---KLNNQ--EWLQDARK
QAAWIMARRKENQ------EYCLFSHLAS-----SDLNPNFF--KGSAGIG-YQLLR---
LAYPES----FPSVLILE-----------------------------------------
>NC_011726.1|c4|2054077-2057313|-|YP_002372173.1|Lanthionine_synthetase_C_family_protein
-----------------------------------------------MNTRKIRESDLLS
IVSRATFLSEKIQDAFKKKVNQQE----------------------FDQNLIDKRLKNWS
R----------------------AVGGGDNLKKRINWDELDLNFLGYVLG----------
-----------SVDVFNNSSLPFWAETLKNIL----ESNLPLFDPINAQNNLPIDSDNPL
AFEEFYLAFIQFN---RYQLYSRF-----------SKNIIEELLTQQAYYALERRLL-EQ
LVNLGTETLLFE--FD-------KFRQNNI-----VTNKSTTSET--PQKARYNTFIETL
LQDKG--LRFFHQYPVLARLLTTILDLWLEYTVEFLQRLQADLSLIELTF----G-----
---------ETKNLGKVKEINTSLS--DYYHQSYVLDLTFL----SG-------KKIVYK
PKNLAIDAAFYKFQDWCNQ----------QNITLPF-KVIKIINQEKYGWQEFVS--PEA
FGEEK-EVKNFYQRAGMVLSMIYVLGGKNCQNIDL-VAQGEFPIIIDADFLMSPLK----
---------KESDESESWFSNSVVKTGFLPSWEGDYLLTAN---AQDSSVLGGIF--PQQ
INSSREWKFI-NTDQMN-LVNKTVVIPPK----NNVV-V-FQEKTVY-----PNNYLEEI
VTGFEEIY-RL--LSKHKEKLLSKESPLLDFKV-SQSKLILYPAVAYKILCKQSLNPQYL
RN---GIDFSL-LLEGAA--RTYLSSEKKPYCWSIL-PAEIKALQQLTIPYFQISCDNDS
LDI---GLDK--PLEH---FFTTSSYQKLMTQL-KSLDEKDLALQIQLIRLSF-------
--YAKKVHLTQGNLKDLGTYCQ-FSPLTSEE--LLEEAVRMGNALVNNAIH--------H
GDNCNWIEL---EYM--YKANRYRLKA--LDNSLFLGRIGVSLFLAALAKITGKNQ-FKE
-------VA--LASI----FSLR--KAIKQGQLPL-----TLSERNLGI---IGYGGLL-
YSF----TKISRF-------LEESTLLE-DGKKIVN----FITKKAITKDHQL-------
--DIIFGAAGAILGLLAL----YQETE----DQQVLDTAIDCGNHL--------------
----------LSQRTETFPKAWLTVSQSKKPL-----TGFSHGVAGIVLSLLRLFSVTGN
----T-----AYLE----AAKEGIEYEKN-TLDLSRQNLP------DLALEQTQINSMTL
LYAW-CNGSAGIGLSRL---GSLPILQ---------LED------IDSEIKV-----ALK
TTQRYCQ---------EINQDIDSLCCGTFGRTELF-VVASQ---KLNNQ--EWLQDARK
QAAWIIARRKENQ------EYCLFSHLAS-----SDLNSNFF--KGSAGIG-YQLLR---
LAYPES----FPSVLILE-----------------------------------------
>NC_003272.1|c5|2423195-2426482|-|NP_486065.1|hypothetical_protein
--------------------------------------------------MNVSKQSLIK
IIERSSNISERLSSSFIFNDRQ------------------------INANQNNAKLEKWY
Q--------------------FIAKGNQHNFEKRLLWDGLDTNTISCVLG----------
-----------NVNLADEKYLPNWVETLKAGMQVATFVIPENSNNKFLQQHRYLDPERPF
PFEEILVPFVDVA---KKKLIESA-------------GSSYYLLSQNAHIQMERSLL-EH
LTGICISPLELE--FS-------IFRSLKSSPLVRFINQLQSNCS--KQQ--YTDFVNKL
LKDG--LLSFFQEYSVLARLIATSVDFWVEATGEFLSRLASDSDKIQLTF----Q-----
---------PEQKLGQVVSVQLAMS--DFHNRGRAVIVIKFA---SG-------FKLVYK
PKSLGLEKAYFDFLDWINQ----------QKINLPL-KLLKIINCSNYGWMEFAE--ALP
CQDQD-AVKHYYQRAGMVLCIVYLLKGNDCHCENL-IACGDQPVLVDLETLLHHRT----
--WLSKDDADAKSIANECLQDSVVGTGFLPGWQILPYEQTEIL-KLDFSGLGGFGE-QEM
PYRAMKWKHI-NTDSMV-IVREYTKLLPK----KNRP-F-GENIDTS-----LNNHSKEL
IDGFRQMY-QF--LQQRKEELLASDSPITAFSN-QKVRLVIRNTTVYASILQNSLNHKCL
RT---GVEHSI-QLDLLS--RAFLSSEDKHPLWPLL-AAEKQALEQLDIPYFTAYSDSNV
IDI---SSEQ--TINK---FLSSSSYDDVIAHL-RQMDDADLAKQISLIRGSL-------
YSCLTNEQLNSLPLENPNLYMDIVAPIERRG--MLQQAIAIAQQLEQQAIR-------GK
DNSVTWIGM---GYL--FEAQRFQLQP--VGNSLYDGCCGISLFLAALASVTNRAE-FGE
-------LS--LASL----QSLR--KTLQDPHIDL--QQKLIGQMGIGGA--TGLASIV-
YAL----VRISEF-------LGEVELIQDAQQLASL----MVINEATVNQAP--------
--GVMTGVAGTILSLLAL----YKATK----EPATLQQAISWGNYL--------------
--------LDTRVTVDEVYQAWTNAEGKVL-------LGFSHGAAGIAYALLQLYAATDE
----P-----IFAS----AAREAITLEQR-LFSLSSNCQD-------LDLVSIDNSLLSS
TTEW-CSGLIGISVARL---GTLNILD---------TDE-----IRQ-ELDI-----NLH
TIHHSSL-------Q-VLD----NICCGNFSHIEML-LVASK---QLSHP--ELLETANN
RATQVLSRANQIG------YFQLLPHLPA-----DVYSFGFC--QGIAGIG-YELLR---
LSCPDL----LPSILLWQ-----------------------------------------
>NC_010628.1|c9|3989164-3992568|-|YP_001866601.1|lanthionine_synthetase_C_family_protein
MPGNPSTAMAHLLTFSLFGHINMLNEIATPELNISSDRTSTLLVKLDRLPCKISEYNLIK
IVEKASTISERLGKTFIPNKLD------------------------KEHYVIGSRLERWC
Q--------------------IVAKGDQESFIKRLSWDNLEIDSVRFALG----------
-----------SVALADTQYLPSWTDTLQKAMEIAGSIAEDVFSQDKQQQYQYLDPEEPL
PFEEICLPFVEVA---KQKLIERV-------------GSSYQLLSQAASIQIGRSLL-KQ
LTELFVESLDLEFSISRAYKSSQLVRLIGQ-----L----QGNSS--RKQ--YVEFVKGL
LSDG--LLAFFQEYSVLARLAAIATDFWIEATADFILRLASDWDEIQQTF----Q-----
---------SDRELGQVVDIKSSFS--DPHNCGRSVIIIKFT---SN-------LKLVYK
PKNLGLEQAYFEFISWINQ----------RGIALPL-KTLKIINCSSHGWIEFVN--PLP
CENQQ-VVKDYYQRAGMILAIVYTLKGTDCHCENL-IACGEQPVLVDLETLFHHGL----
--WMREDSPEAILIANEKLFDSVIATALLPGVRVFNYKQTNDLVNLDFCGLGDFND-KQI
VARMQKWVDI-NTDSMTRGEEECNLLSEN----NNQP-F-GENLDTS-----LSKHVEEL
IAGFKQMY-QF--FIQHQKALLAPDSPIAAFTG-QKVRLVLRSTQLYSTLLQNSLHPKYL
RD---GADRSI-ELDVLA--VGFTSLKDKHSSWPML-APEKQALEQLDIPYISAYSDSNA
III---NSDT--TIDK---FVETSSYNDVITRL-KELNDVNLAEQVSIILSSF-------
YSSQTFEKLDLSNLPNTTPNLDEIIHLSEEA--ILDRVIEIAQEIKQRAIY-------GS
NNTVAWLGM---TYD--FQGQYFQLRP--IAHNLYNGYCGVSLFLAALASVTNKAE-FGD
-------LA--LGTL----QSLR--KGLQERDPEL--EQALIKQMGMGGA--TGLASVV-
YTF----VRIAGF-------LSEPKLINDAQQIASW----LKVDATTVEEEL--------
--GLLKGAAGTILSLLAL----YKVTQ----ESDTLEQAIAWGNYL--------------
--------LDRRVTTDTGYKIWTNAEGEPL-------TGFSQGIAGIAYALLQLYAIAKN
----S-----DFLS----AAKEAIAYEQS---------------------CSIAADKLSP
LANW-CHGLPGIILARL---ASLSILN---------TEE------IRQEIET-----SLP
KIQQPSL--------KALD----NLCCGNFADVEVL-LVAAE---QLSRL--ELLETARL
QTSLVLHRSAITG------SFQLLPKLPL-----KVYHPGFS--QGTAGIG-YELLR---
LLYPNK----LPSVLLWQ-----------------------------------------
>NC_011884.1|c6|5342198-5345587|+|YP_002485891.1|Lanthionine_synthetase_C_family_protein
--------------------------------------------MDRARFNLNIENSLNQ
IIANSWYFWEVLAADQSCVGDRSFDSEGHEAT--------------PQKLINQNLLDRWC
Q--------------------VTAEGNWEIFEKRLQWQGWDLHKAQTDTT----------
-----------ATKPGQQWSPPDWSATLRQIM-ENAAVMVQEQSFSTFAPESCLSPDHPT
PFAEVFLPCLQVA---RQQLLQQL------AAAMPSDESPLTLLSNQAYLNLERGLL-SE
LVNLWIRPLMQG--FN-------LVRPCGE---PSLSSSSLAVEPS-NSKIYYEQFINQV
LENG--FVGWFEKYPVLGRLTATSINFWINSTITFLRHLQTDLAEIQAAFATDSL-----
------SDRPPANLGQVIKIEPCLS--DRHEQGKTVISLTFA---SG-------LKLVYK
PKNLDLDLAYSQFLSWCNQ----------TGLSPSL-KVLKVLSRNDHGWVEYVE--HFP
CADEV-AAQRFYQRAGMLLCIIYLLRGTDCHYENL-IASGEYPVLIDTETLLHPDV---K
PIAQSLEAMERQSTEQFKFWDSVLQTGLLPQWEVGKENSSV---AYDMSGLGSSFS-PSQ
SRQVQIWQDI-NTDRMR-LEWQAEPVPPN----KNVP-I-LDGEPLA-----GYVYLDNI
VGGFQQMY-DI--LTAHQNELLGPSELLTEFQA-KRVRFIFRPTQVYAKILHYSLSPKHL
QS---GLLRSI-SLDILS--RPFLAANKKPLMWDIL-TAELQAIASLDIPYFACSSDTTT
LSV---GVER--PIAA---YFFASSYELVRNRF-ASLKSADRAYQTSLIRGAF---YARV
AQSTPSPGDSKAQAFPLPDDFKTVDRLNQQK--LLAEAVEIATEIKQNALW-------EE
DGSVDWIGL-----TFLTQSNHFQFQP--LGDSLYHGRCGIALFLAALDLVSETQQ-YRD
-------LV--MGCL----KPGR--SLLCHSPAAL--TYRYLDYMGLGGS--TGLGSIL-
YAW----VRLSQF-------LQQPDLVEDALRASNL----ITPELIQADTSL--------
--DLVAGVAGTILGLLAL----YHATD----DPTVLARAIACGQHL--------------
--------CQTQIKEGTTAGGWVTLAQKRPL------TGLSHGAAGIAYALLQLYHATDN
----P-----TYLQ----AAQQGIAYEQR-VFNPQVGNWP--------DFRSGTEENPQF
MVSW-CHGAAGIGLARL---GGLDILD---------TPE------IRQDIEN-----ALE
TTQKSAQ--------FRID----HLCCGTMGRIETM-LVAAQ---KLARP--ELMDSEFG
KVTWVVNRAKAEG------TYQLFSNIPN-----AVFNPVFA--LGTAGIG-YQLLR---
LAYSDQ----LPSLLIWQ-----------------------------------------
>NC_011884.1|c1|2855759-2859139|-|YP_002483601.1|Lanthionine_synthetase_C_family_protein
-----------------------------------------------MKYNLNLENTLNQ
IVANSWYFWELLGADQSSNADLSFNEQDQEAG--------------PQRLFDQKLLDRWC
R--------------------VVAERNWEIFTKRLQWQGWDLDKVQSYPA----------
-----------ATKPGQQRSTPDWLATLRQIM-ETAAVMVQEQSISTFAPESCLSPEHPT
PFAEVFLPCLQVA---RQQLLQQV-----AATTPPEDESPLTLLSNQAYLNLERGLL-SE
LVNLWTRPLIHE--FN-------LVRPFNQ---NSLSSSILPVQP--SSRVYYQQFINQV
LEHG--FADWFQKYPVLGRLTATLIDFWLNSTLNFLRHLQTDLAEIQATF----A-----
--TDFLSDRPSANLGQVIEIEPCLS--DRHERGKTVTALRFA---SG-------LRLIYK
PKNLDLDLAYYQFLTWCNQ----------QAFSPSF-KVLKVLSRNDHGWVEYVE--HYP
CEDEV-AVQRFYQRAGMLLCIIYFLRGTDCHQENL-IASGEYPVLIDTESLLHPKV---K
PIDQSLEAMKRQSSENFKFWESVLQTRLLPYWEVVKQNSYG---LQDTSGLGSSFS-PFQ
NREVQIWQEI-NTDQMR-LEWQTESVPPP----KNVP-I-LNGKPLT-----AYVYSKDI
VSGFQQMY-DL--LTAHRNELLTPAGILAEFQT-KRVRFLFRNTKVYARILHYSLSPKHL
QS---GLLRSI-WLDILS--RPFLAATEKPLMWDIL-ASELQAIADLDIPYFASGSDTTT
LSI---GVER--PIAA---CFFASSYELVRNRC-ASLNPADRAYQTTLIRESF---YARV
DQAAPSPLDNPVQAFPLPSDFKTVERLNQQQ--WLGAAVAIATEIKQNALW-------EE
DGSVNWIGL-----AFQYRSKHFQFQP--LGDSLYEGRCGIALFLAALDRVTETQQ-YRN
-------MV--LGCL----KPAR--SLLCHSPAAL--TCNYLDLIGLGGS--TGLGSIL-
YSW----VRLGDF-------LQQPDLIEDALIASNL----ITPDL--IQADTSL------
--DLVAGVAGTILGLLAL----YRATA----DPTVLAGAIACGQHL--------------
--------CETQIKQGATAGGWVTLAQKCPL------TGFSHGAAGIAYALLQLYQVTDN
----P-----TYLR----AAQHGIAYEQR-VFNPQVGNWP--------DFRSGPEENPQL
MVSW-CHGAAGIGLARL---GGLDILD---------TPE------IRQDIAI-----ALE
TTQKSTE--------FGID----HLCCGTMGRIETM-LVASQ---KLARS--ELMDSELG
KATWVVNRAQTEG------TYRLFPNIHN-----PIFNPVFA--KGTAGIG-YQLLR---
LAYSEC----LPSLLLWQ-----------------------------------------
>NC_010631.1|c1|94655-98005|+|YP_001869999.1|lanthionine_synthetase_C_family_protein
--------------------------------------MEEREMINNEFKTTSTQVKVVQ
IASKATFLFERLINNNLSLNVTH-----------------------FNEKEADKRIVDWC
K--------------------VIAKGDLEVFHKRLEWSNWNIETIRDLFG----------
-----------TEPIFDSQNLPNWVKTLSDII------HILSESNIQKISPNASEPENPY
PFEEILLALVAVA---RQKLLNCL-----GFDSLSPDTLPLKILSEAAYLNLEKALL-QK
LFNLSAKALEFE--FS-------ISRSFGKNFLSQFIKNTKNVHS--TEL--YKTFIQKS
LADG--LLGFFQKYPLLARFIVTTIDFWVEATKEFLERLDADLGEIQQKI----H-----
---PLANTENYQAFDTVIEIKSAIS--DSHNQNRSVIALTFA---SG-------RKLVYK
PKNLGLEVAFCQFLEWCNQ----ELTLGQNHPSLNL-KVLQVINRGDYGWVEYIE--QKP
CEDEA-AAQRFYIRAGMLLCLLYVLGGTDCHNENL-IACGENLVLVDMETVMQHEA----
KLMGVSLDQSATSLATNQLFDSVLRTGLLPMWEFAANDSI----ACDFSGLGSVEV-QPV
PIPMPVWKFI-NTDDMH-QGYEKLDRPLE----ANIA-L-LNGMPLS-----PKNYINEL
VIGFEQMY-CF--LMRQKEVLLAANSPLNVFHA-QKVRFIFRPTRVYGMLLGQVMTPEFL
QH---GLDWSI-QVDVLS--RSFLTNGDKPLAWQIL-LEELKAISQLDIPYFSGLVDGDT
LPL---GEEK--AIVE---YFKTSCLSQVRSRL-QKLNENDLAQQLSIIQLAF-------
-YAKEARILQTNPSSSISQEAEYDSALVLTSAELLEQAQEIASEIQNRAIC-------GA
DDSLTWISL-----TYVLSAERFQLMP--LGYSFYDGNCGIAVFLAALARVTGKTL-YRD
-------LA--LRAI----QPLQ--NYLQTSDTKT--DLDTALNLGIGGA--TGLGSII-
YSF----VKISQF-------LEVPQLCA-DVQRFAN----LITPTAISADRKF-------
--DIIGGAAGAILGLLAL----AQE------QPMVLKQAIACGQHL--------------
---------LKYCNEVFGKTSNLKGL-----------IGFSHGAAGIAYALLRLYAVTQD
----T-----DYLD----AARMAIAYENA-LFYPSVGNWR------EITPVYDPASLPVF
WSTW-CHGAPGIALGRL---GSLSIDR---------SEQ------ILTDIEV-----ALK
TTQNTAL--------QTID----HLCCGNLGRCEVM-LVAAQ---KLHNP--DWYQAAQQ
LAAIAVARATRKG------RYELFGDLPN-----FVYNPSLF--QGAAGIG-YQLLR---
LAYPEE----LPSVLLWE-----------------------------------------
>NC_011884.1|c3|4009289-4012642|+|YP_002484655.1|Lanthionine_synthetase_C_family_protein
--------------------------------------------------MEMPELDLRQ
IVAQAHSLSECLDRPRYQSQNSN-----------------------ADSTVACQRLEHWC
E--------------------VAAQGDWSAFQKRLDWDDLDRESVNYVLS----------
-----------SPADPAPDGLPPWTDTLKAII--------ATANQPLPDSSLPIDSADPQ
PFEDILLPIVIAA---RQKLQNQL-QSSPAILNATINASVFELVSESGYLELEKEFL-KT
LINLSTKTLDHE--FT-------NFRPLGHNLLNFF----AGTQSTEPSKELYYKFVNGL
LQDG--LLTLFKQYPVLAKLIAIATDFWVESTLEFINYLAEDLPELETLFASSALTESQS
NWQSLSPSFHSAGLGQVVSVRPSLS--DFHNRGRSAIALTFS---SG-------LKLIYK
PKDLGLDVAFFDFLAWCNQ----------QNSPLDF-KILKILNRGSHGWVEYVE--QQP
CGARA-AAQRFYQRAGMLLCVLYLLGATDCHYENL-IASGEHLVLIDTETLLHPDA----
NPIDGSAVEMVTAATDLQLADSVLRTGLLPNWIFSADNRI----AYDLSGLGSCDP-QQA
PWRLPRWQFI-NTDEMR-LVNQDVTMPLQ----QNIA-V-LEGQPLS-----PDGYLAEI
LTGFEQMY-NL--FLEQRQYLQSSLSPLVPFNH-QPVRLIFRHTQVYGVILQKSLEPQWL
QD---GRDRSLQLEGLSW---ALLACEHKPLAWPLL-KVELAAMEQMDIPFFQASTSHDG
LEI---EPGL--VIPR---YFQAASYAQVLNRL-DKLNPADCTLQLAMIRGSF----QAR
IAHQPLTSKLPQGAVASISDRLPTQTLIPDQ--FLQEAIRLGHLLETEAIR-------GK
DGSATWLGF-----DYIANADRFQMVA--LKDALYEGASGVAVFLAALSRVTNQDR-FGG
-------LA--LGAL----QPLQ--KFLYSHDRPQ--LHHWAKQLGIGGA--TGLGSII-
YAL----TKISDL-------LQDRSLHQDALTIAQL----ITPELIAADQQF--------
--DVIGGAAGAILGLLPL----YRATG----DTSVLTTAQACGQHL--------------
------------LANQEKGGAWKNFAEQPL-------TGFSHGAAGIALALLQLAAQTGE
----E-----VYRQ----AAIAGISYEQS-LFSATAANWP------DLRSIVQQEGLPGF
SVSW-CHGAPGIGLARI---GGLDSYA---------TAA------IQQEIEI-----ALQ
TTQKQGA--------YGLD----HLCCGTFGRIELL-LVAAE---RFDRP--ELQETARY
LATQVVTKATEQG------GYRLFANLPP-----AVLNPNFF--QGIAGVG-YQLLR---
LTHPNQ----ISSVLLWE-----------------------------------------
>NC_011884.1|c2|3022764-3026030|-|YP_002483742.1|Lanthionine_synthetase_C_family_protein
----------------------------------------------MLQTAESETKSLQP
IWSGSHSLFTSLLSANPNFSAAP-----------------------MENAQLEARLKRWC
E--------------------VIAQGNWDKFKRRLQWDGLDLEQVRSLLD----------
--------------GSPQESEPEWTETLQAIM--------AASRSGMQPEPSPIDPENPQ
PFEDLWLPAIAVA---RQKLLVHL-------------EQTPVFLTEVALHQLERSLL-QR
LVGISIKTLDAE--FS-------RTRPLGQNLLTQLMGTVAKNSG--NEK--YQAFISKH
LADG--LLSFFSTYPVLARLVTTALEFWVEATAEFLQRLAKDLEQIQARF----H-----
-----------IQEPQVTAIQLNLS--DSHKRGRSVFILTFT---RG-------EKLVYK
PKDLSLEAAYSDLLIWCNQ----------NGAPLPF-KPLNVLNRGSYGWVEFIE--QQP
CSDYL-AAQRFYQRAGMLLCLLYVLRGTDCHHENL-IAWGEHPMLIDMETLLHHQA----
---NLLDETETADLAGLSFFNSVLRVGLLPRWDFNKDNRV----AYDISGLGSDVN-QSA
PRKAARWQGI-NTDDMH-LSYQEVPLPPC----KNLA-L-LNGQPLA-----IADYQEDF
LNGFEQMY-QF--LVSHRAQLLAADSPLRLFQD-QPIRFVFRATMVYGVILQNTCAPDLL
KS---GCDRSI-ELDILS--RAFLTVLQKPDAWPIL-HAELRAMEQLDIPYFVASSSSDA
LVL---EDGT--EIPH---YFKAPSYDQMIACL-EQLGQADLDRQMALIRGVL-----AA
KIARPVGFQAHSSTAATAANWQDLEPLSRDA--LIQQAQAIAAEIASRAIR-------GS
DGRVNWLGL-----SYVPNAERFQLQL--LSHNLYEGNCGIALFLVAVDHLTNSDR-YRE
-------PV--LAAL----QPFR--QILHRQEPEI--LQRMVQRMGLGGS--SGVGSMI-
YCL----VKISQL-------LNEPTLLSDAHLLARL----ITPKLIAADQSL--------
--DLIGGAAGAIVGLLSL----FSVTH----DPEVLAIAIACGQHL--------------
--------LQQQVSINGSPKAWKTTADCPL-------TGYSHGAAGIAYALLKLYEASKD
----M-----AYLD----AAVEAIAYEQS-VFSAAVGNWP------DFRSFAFVNGKPGF
MSSW-CHGAPGIALARL---GGLPILD---------TPE------IRRDLEV-----ALH
TTANNQF--------FGVD----HLCCGTFGRIEVL-LLAAELGLPSGES--NWQDIAFR
QATWVVQRAERTG------TFHLFANLPQ-----PIYHPGFM--QGTAGIG-YQLLR---
LVEPT-----LPSVLLWQ-----------------------------------------
>NC_010628.1|c10|4118476-4121793|-|YP_001866693.1|lanthionine_synthetase_C_family_protein
-------------------------------------MKNLAITQQLVPSQQITPHDLAI
IVANASFLGERLQTEQFVMDGDR-----------------------IHEQEINHRIDRWG
Q--------------------VVAQGSWDMLHKRLQWDGLELDSIRPRLG----------
------------SVRLAKQLLPDWAETLGQII------QTAKEFIPVREAFLPIESQNSI
PFEDLLLPAIQVA---REQLLSRL-----GFVQLTHDSLPLSIFTEAAYRSLERSLL-QQ
LARLCSKTLDLE--FS-------QVRSFGRNLLNLLELKTKSGN---NTQ--YTKFVNQL
LQDG--LLTFFQKYPVLGRLVATTVNFWVESTGEFIERLAHDTKDIQQIF----G-----
---------STSAKDKVAAVQTSLS--DPHKRGRGVILLTFE---SG-------LKLVYK
PKDLKLEAAFNNFLTWCNH----------HSQLLDF-KAIQVINRDDYGWVEYVE--HQP
CVDEA-AAARFYQRAGMLLCVIYVLRGTDCHYENL-IASGEHLVLLDMETLLHHEA---K
AIENSPDAQEWETIAMQQFWNSVLRTGFLPRWDLSSDRTV----AYDISGLGSTAL-QQS
PRKVPRWQLI-NTDDMY-LRYESVTLPIE----KNVP-R-IGDTVLS-----PHDYQAQI
VAGFEQMY-RF--LMAHKQVLLAPNSPLGVMQK-QQVRFIFRHTRLYGTILQKVLTPDYL
KC---GVDYSI-ELEQLS--RAFLVAQEKPNAWPIF-NAEVQAMEQLDIPYFSASAASDE
LCV---GEHL--SIPG---YFKQPSYQQTLAQL-LAMDETDLARQVAIIQGSF-------
----YAQLAQTSTGEHEKWQAESLPLLTTEQ--LIAEAQAIATQLETRAIM-------DF
DGSINWIGL-----VSVPEAERFRLQV--LDHSFYEGRCGIALFFAALAQITDDPRSYE-
-------LA--LKSL----QPLR--QQIQTLDLES--RQRMASFAGIGGA--TGLGSMI-
YAL----VKISQF-------LGDETLLQDAQALASW----ITSELIAGDKKL--------
--DIIGGSAGAILGLLSL----YQATG----NENILLKAIACGQHL--------------
--------LAYRYSETGATRAWQTLGKIPL-------AGFSHGAAGIAYALLRLYTVTQD
----Q-----SYLA----AAQEGIEYERT-VFSESRGNWP------VSHKAERTGGKVTF
PSQW-CHGAAGIGLARL---GSLEILN---------TAE------IQQEIEI-----ALR
TTENFGL--------EAID----HLCCGNMGRVEVL-LVGAQ---RCDRS--DWHQIALQ
NATNVVARANRTG------AYQLFANLPS-----SVFNPGLF--QGTAGIG-YELLR---
LANND-----LPCVLLWE-----------------------------------------
>NC_010628.1|c14|6251419-6254724|+|YP_001868329.1|lanthionine_synthetase_C_family_protein
-----------------------------------------MSQLFVQSSQQIPLSDLAT
IVTKASFLWERLNTKQFAIAAGL-----------------------LNEQKIDHRLERWC
Q--------------------VVAQGNWNTLQKRLEWEGLDFDTIRPQLG----------
-----------TVEFNAGQPLPKWAETLQKII------QTATEFQPELETFLPTDSENPI
PFEDIFLPIIKVA---RLELRTRL-----------EEHLPQLLLTETAYRNLERSLL-QR
LATFCTKTLHFE--FS-------QARPFGQNLLNLLGLETESEKT--KTH--YNKFVNQL
LQDG--LMAFFCKYPVLGRLVATVVNFWVDFTAEFLQRLAEDKADIQQIF----G-----
----EFGSEQPDYLGKVAEIKTSLS--DPHKQGRTVILLTFE---SG-------LKLVYK
PKDLGLEVSFNQFLDWCNQ----------HSHLLDF-KVIQVLNRNNYGWVEYVE--HQA
CIDEA-AAERFYQRAGMLLCVLYTLRGTDCHHENL-IASGEHLVLIDTETLLHHEA---N
LIENSPDMQGSEANAEQQLGNSVLRSGLLPRWDFSSDRRV----AYDVSGLGSTDP-QQA
PQKVPRWGLV-NTDEMH-LGYEFITLPIQ----KNVP-Y-IGEIGLS-----PNDYQAQI
AAGFEQMY-RF--LMDNKDMLFQPKSPLTVMGK-QQVRFVFRPTRVYSVILQKIWASDYL
KD---GIDYSI-ELERLS--CAFLVAQEKPNAWHIL-SAELRAMEQLDIPFFTANAASDE
LSV---SDDL--SIPH---YFKQPSYHHVLRQL-QAMSKTDLARQIAIIQGSF-------
---HAKLAQTSSEESEQWDVES-APLLSSAQ--LIEEAGAIANALEKTAIL-------DP
DGSINWIGL---NYV--PEAERFRLQV--LGSGLYDGRSGVALFLAALNKVAGEPR-LRD
-------LA--LRTL----QPLR--RQIQTFDLES--QQRMSRLMGIGGG--AGLGSLI-
YAF----VKVRQF-------LNDETLLA-DAQALAE----WMTPEL----IAADKKL---
--DIMSGAAGAILGLLSL----YEVTK----DATVLEKAIACGQHL--------------
--------LSRQVSYKGAPKAWQTLGEQPL-------TGFSHGTAGISYALLRLYTVTQN
----Q-----DYYE----AALAGIEYERS-VFCESQGNWP-------DFRSAEMNQPPGF
PVRW-CHGATGIGLGRL---GSLGVID---------SPE-----IEQ-EIEI-----ALQ
TTQNYSL-------Q-DSD----HLCCGNLGRIEVL-LVGAQ---RCSRS--DWHQIALQ
NAANVVAKAKQTG------AYQMFTNLPS-----SVFHPSLF--RGTAGIG-YELLR---
LATDD-----LPSVLLWE-----------------------------------------
>NZ_ABYI02000040.1|c1|14959-18105|-|ZP_03780146.1|hypothetical_protein
----------------------------------------------------MITYEVHM
SDTRESYLWERTYDNTEY----------------------------TPPKTDTEELKFWN
R-----------------------TMGEEFFKELYTNIPKIQSYLTN-------------
--------QPYETDRGEAARLFNKYECNERGI--------------PQEAADFIAKYESE
NFIQFYTPYLAAG---ILRLKHLI--------------VKDDICRPEVYEQYLRSLF-TK
IQKICIRTLIHE--IR-------QCKVNGE-----L----EGKDA--SGE--YEYFIKQ-
VVTGEWRNSLFGKYPVLARSVAEAVELSAQLYAEAVNRLSDASKEITEQI----C-----
---------EERTFTYITGIEGDIA--DSHRGGKSVLKISLD---NG-------MTVIYK
PHSLENETVFHELLRQLGN-----------RCGMEM-YRMKKVEGSDWGFCECVK--HQE
CACRE-EMERYYRRMGLCIFVFYLLGTNDIHSENI-IAHGEYPVLVDLENIMSAPE----
----EFEAMNITEKVQYFLHKSVLYSGALPSCKWISGGG-----NVNVSGVGGRGG-SRM
PFKVPRVVNS-RSSDIQ-IQYVHPVLDPD----DNIP-V-LQGRPAD-----PERYLDDM
TEGFKAAY-MW--ALCNRRELQQWTEPLKC----VESRYLLADTQRYVMCQNSSYHPALM
TD---GARRQI-YLYTMW----YGRSMESKGDRQVV-EWEVKDLLNHDIPFFYFISSEKH
LYH---ADGK--RLEG---YFARTSYDMLLERI-QDLNEADMSNELELIEMTI------V
LQSQAEKELMNEGTEDGGSVAGEFKPDEKNK--LLEMAVEIGERLLAGAVN-------VD
GSEKGWYMA----CVTTDGSLGWMIQP--VDMYLYSGVMGIAVFLHLLHEYSGSRE-FGC
-------AA--SQLD----------RQLFAYTDYM--RETKADDMASGIY--NGEASIV-
YGY----LFLYKR-------TGNEEYLT-YARRHGE----IVVRCACRDVNY--------
--DLLDGLAGAVYACCLL----YECTE----DEGWLKCAKEAAGRL--------------
---------IKAAVKTEDGLCWKNAQSEEAL------LGMSHGNAGIMTAFAALCRVCKK
----A-----EYME----AFRQALCYEDK-CYDPGLKNWT------DFRAVKSADRKLAD
TVAW-CHGAGGILMSRL---MSANMEQ---------EEL---GDLIEFDVKRASAK-LAG
KCVREGM----------------CLCHGSLGNLLML-QEYCK---FTGDK--EAEHIRQR
NLKYVYEKLKDND----------FCLLPQ-----ERYNPGLM--SGYTGVG-YGLL----
ALYDDR----LADILCLEI----------------------------------------
>NZ_ABFY02000050.1|c1|82478-84661|-|ZP_02433053.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MH-------VYKEKEK-----L----RGETP--IKE--YNYFCEKY
VSTFEFVHELFEIYPVLYRIIEEKIENFIKYYIEIFDFFEKDKNKIGEKI----C-----
---------GGKLVKRIEEIDFSLS--DSHKSGKRVAKLKLD---NG-------MWILYK
PRAMKNDEIYMQLIQWISH-----------HIGMKQ-YEYPFLTYEEHSWTYIVE--QSS
CNSEK-ELENYYVRFGIHLFLTYLLGAQDLHYENI-IAAGEYPVIIDLEALSGIPR----
----KQKGRSIDEIIYHQLVESVWNTGLLPFCWGTQRRK-----GVECSGINGKGG-QKY
LFKIPVVVEG-GTSNMH-IEYMCPISEEK----QNLP-K-IKEGFID-----ISHYKAKI
KEGFCKAY-HI--ALQRKQELY---CWVTKLKN-CECRCFMEDTQRYGMLLFSSYHPQLL
KD---GAEREI-FLQAMW--------DNRNKNDYLIVDSEVKELLRGDIPFFSFHMDSKN
LLL---GNGG--VISN---YFMNTPMELLYQKV-RLLNIKDMEKQCEYIDISF-------
DILQAPKQQCVNKVYKTCEKKVDCSVVERNNTANSKLVDMYIERLLKYKVF----N--YD
NTEISWYTI---QL---EDQYGWSVKT--MNIYLYDGLAGMFLISCFLQKYQNTRE----
-------IAKINKIL---------QSTLFHYTEKGYESMKNLQSQNVGAY--EGESSIL-
LTY----LIAYQY-------KKEKIYLD-YAKKHIK----IIEQLIQMDTNY--------
--DVLKGNAGAVLVLLKL----YGICP----EKKYLVLAEKAVDRL--------------
---------QERALNLEHGVGWEIEKQVPM-------AGMAHGNSGILMAFVGMWKKTNK
----S-----KYFE-----------FAKK-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------Y-------
-----------------------------------------------------------
>NZ_GG696053.1|c1|8505-11135|+|ZP_04857854.1|conserved_hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
LENICIRILILD--IS-------EKKSNHE-----L----YGFTV--HEE--YNFYIKHF
WKNESYKCDLAIRYAEGSRLQKLKEKYFVILQNEINEKINIDKDMISKKF----H-----
EN-------MNEFQM-LN-K--DQG--DIHKNGRSVSKIEFD---NG-------SILYYK
PHSLDKDIKYQQLYKYLCE---KA------GI--SC-REVRCLSRQTYGWEENIE--NKS
CNTKE-EIERYYFRLGIHLFLGYALGATDLHGENI-VAYGEHPVIIDMETYPGYITKNSG
S---S-TEEKAEIKIREKIMTSVLNTGILPVLTW---GTGNN--RVLMSAVNMHGK-IRT
PFKMPVVKDD-KTSNIH-IEYEQVEFEIK----ECIV-R-LNGEVVN-----SEEYTGEI
IRGFRMAY-TE--ILQNQK--LRNMLKT--FFQ-GKSRVILRHTQQYYMYLFASFHPDYM
KD---RKQREE-LLQVLHKK-GETQLQKEL----R--DYEIQSLLELDIPYFEIDGNSRS
IFDGN-GK----EYQG---YLPCTPYESWIEHM-KQLSCQDMEQQCDYIRLSM--GLLNH
G--YIGEKN-------PR----------WAD--ENTCIHQIAEWICRTAVI--D------
GADIGWAGL---HF---WDNGYWSLKP--CGMYLYDGIAGIVLFLAKYLDRYQDSS-CRQ
DVEKIYKLA--IEKL----EKYT--DLRCEQN-------EVPEPLATGLY--DGESSIV-
YVY----LILYEI-------TGQEKWIK-NAQKHFE----I-VA-K--LLPK-DENM---
--DYLSGNAGAIVAAMKL----YQLT-GE--IEY-CTAAVETEKDL---WKK--------
--------GQRM---EVGY-GWKLKNL-KYP--L---SGLSHGNSGFLMAYVELYKMTYD
----Q-----EYLK----KIKLLLSYEDI-LYSEDLKNWIDLR--D----P---D-GRKT
MRGW-CHGAPGILLSRM------SIMD---I-LP--DD------------KQ-----IKK
DILRAVSTLFHNERE-KKI----CLCHGMTGNLLIM-KKYLE---KNPDD--DLRQKYER
QFSNLKEQLQDMR---S---LMVT----------ETLNPAFM--NGITGVG-MAMML---
LNMD-------------------------------------------------------
>NC_008536.1|c4|8034431-8035573|+|YP_827626.1|lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MKPQYL
ET----------------------------------------------------------
------------------------------------------------------------
-------------------------------------ADRICARLCRDALW--------S
GGLCSWTAD---RSGG-RGGWHGALLP-----HLYSGTAGIALALWRVAAATGDSI-CRF
-------TA--RGAI---------ARSLVMLPVRQ-----------NGYY--AGCLGIR-
HAA----AEILGE-------LDEAALLREAEPNRET----L-------------------
--DIIGGSAGAIAALLDF----ARRT-RR--CAY-LEMAARHGDLL---IAE--------
--------AIRE----ADTWAWQTIPDHPPV------TGFSHGTAGIGWALLELWRATSE
----A-----RFRQ----AALGAFAYERS-SFHPG-GGWP----------DLRGD-APVY
QSVW-CHGAAGIAYSRL---RAWQILG---------DAE----CLDEARIGL-----AIV
RDGLGGL---------ENF----SLCHGSAGNGDLM-IYATE---VLGEQ--EWMAAAER
VGQDGIERYDRPR-------ALWPSGLMR-----AHETPDLM--WGTAGIA-YFYLR---
LAGAA-----APTLLLPCARSD-------------------------------------
>NZ_ABIB01000001.1|c2|528819-530081|+|ZP_02160368.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MNN
IATTQ---------------------KTDVHM----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------YVKTAHNIGKYLAKEALW--------Y
KDMCNWTGH---EVSVFDEKYQTVVKA--CSIDLYSGLTGIALFLTELYTKTQDPI-ILH
-------TL--NGAL----------NTINFNLKND-------KLNNFGYY--SGKIGAG-
YTL----WRIGKK-------LANEEIAA-TGLRYVK----SVKDEEIADYEV--------
--DIISGAAGSISVLLKL----YYAEQ----DEEYLAIAEKCGEFL--------------
---------LKKAMKNGNTYSWMTVDASNAL------TGYSHGASGIASALMEMYATTKK
----E-----EYWH----AAMGGYNYEKQ-WYNEQAQNWP-------DLRQYEGKKPLNY
GTMW-CHGAPGIAIAQLKAYEMTKHDY------FLHEAK----VALETTKRS-----VIQ
ETQINSK---------ANF----SLCHGLAGNADIL-LYASQ---LLENP--EYVQIARN
AANLGISQYDATGVIFPSGVNDPSGLTIG-----QQENPGLM--LGMSGTG-MFYLR---
LADIM-----IPSALVP------------------------------------------
>NZ_ACMS01000387.1|c1|379-3402|-|ZP_04183889.1|hypothetical_protein
--------------------------------------------------MTVMIQTVDK
RLIHALTIEERAEE--------------------------------TSYVHEPTAWEKWQ
G--------------------RKSLLKQVDVEFMLNHYKDEQSFKKGIQP----------
------VAEQDVEGMLLKVEKSEWYKLFNEVF----------------ATYEENERPATY
DYTYAVRFFLQYM---KRFLKEEL------------DTSTHYKFHIDAVVSIVQGYS-EE
LMGFMSRTFAHD--IQ-------VMKETHG-----L----DGGTG--KDR--FAYYMQHR
FENVEKAKEFFYDYPALLRLIAVKTTFFKRNISEFIKRLNDNVYEITEKL----------
----------GHSSRTIQRIGLSAG--DSHNQGKSVMLVYFS---EH-------ELLVYK
PKDLQYTKKLETFFNFLNE-----------TLGTDF-YSVQRIIREDYAFEQFIE--RQP
CESEE-DLRGFYRRYGELIGLAYMLRGTDFHYENI-IAYGNRPVLIDVETFLQQHV----
---PLEFGESAHVTAKERQLDSVILTGLVPFHILADRSENKQQ-GINISGLSYGT--QKA
PFKILKLNNH-STDEMK-FEYMEHYISGK----NNTPL--LNGEEVP-----YEAYREDI
LVGFENFM-KK--CMAHRHVII--EQVQMLFVD-SRVRNVVRPTQRYVDLLQFSYHPTCM
QN---MIEREK-VLHNLF--------AYPYRDKRIA-IFELQEMLEGDVPQFFNRTSQRH
LLN---NNDI--EIKE---IYKESIVDQIVNSL-MHLAPKQIEEQRLQMEMAM-------
-----------GIYNHTEHVPEQSNAVIQKD--VLVVVKEAARKLLKEAVY------DEK
THSMTWIDI--------LCKTDWKYEA--MNNQLYDGLPGMYAFFSALQATDKQRD-IDY
-------VDVKKRIL----------NTMLVIPSVP----------KASAF--YGNGALI-
YPL----LLDAQL-------NNNEEALSLACQIADQ----VMTFEVEKSN----------
--DWLTGQTSLIAIFKQL----ADVTK----NPTYNNYALTLSKQL--------------
--------------TYDKEFPY---------------VGFIHGNSSVYYVKALMDKQSPS
-------------------IYEWMREEDT---HWNENHWR-----------DPRPDKPNC
VHAV-CHGSTGILLNRI---MVEELTH---------KEV-----GVKQRLQV------MN
NLFNQKK----------ED----SICHGTAGDIELL-LTLQA------HDIGTYQPLLQQ
KVSQLLANYYEYG--------AFRLQGYE-----TIQSKGMY--TGVTGVL-YTLLR---
TLNPT-----LPSFVLLQLPTRKDG----------------------------------
>NZ_ACMT01000314.1|c1|139-1572|+|ZP_04177627.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MQN----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MIEREK-VLHNLF--------AYPYRDKRIA-IFELQEMLEGDVPQFFNRTSQRH
LLN---NNDI--EIKE---IYKESIVDQIVNSL-MHLAPKQIEEQRLQMEMAM-------
-----------GIYNHTEHVPEQSNAVIQKD--VLVVVKEAARKLLKEAVY----D--EK
THSMTWIDI--------LCKTDWKYEA--MNNQLYDGLPGMYAFFSALQATDKQRD-IDY
-------VDVKKRIL----------NTMLVIPSVP----------KASAF--YGNGALI-
YPL----LLDAQL-------NNNEEALS-LACQIAD----QVMTFEVEKSN---------
--DWLTGQTSLIAIFKQL----ADVTKNPTYNNYALTLSKQLTYDK--------------
--------EFPY-------------------------VGFIHGNSSVYYVKALMDKQSPS
-------------------IYEWMREEDT---HWNENHWR-----------DPRPDKPNC
VHAV-CHGSTGILLNRI---MVEELTH---------KEV-----GVKQRLQV------MN
NLFNQK----------KED----SICHGTAGDIELL-LTLQA------HDIGTYQPLLQQ
KVSQLLANYYEYG--------AFRLQGYE-----TIQSKGMY--TGVTGVL-YTLLR---
TLNPT-----LPSFVLLQLPTRKDG----------------------------------
>NZ_AAYG02000011.1|c1|197235-198383|+|ZP_02040706.1|hypothetical_protein
------------------------------------------------------------
-MKKSSYLSERVYNV-------------------------------NPSEINMESLEYWK
K-----------------------------ILKEEGLQYVKKNHLEYFFG----------
------FLNNCSFSSHEKCQHQNFVEMSSKRE-------------------TCRHECDEM
IFGAFYDPFVQVA---NKQLRETV--------------TQKRYIKESILVDFQKSLF-NL
LNNLCIRTLIYE--MY-------ICGQEGL-----L----EGNEF--EQ---YQYYIDHF
LKDKQYLNDFFSLYPVLERRINEIIQNTIDIYKEVIERIDTDANEIMREF----N-----
---------IVESAFIVEHLSTDFS--DSHKNGRRVFCVEFV---SG-------EKILYK
PRCLQNEIKLQEITNYFYK-----------ICNLGS-YEYCILDKGKYGWCEIVT--QKD
CESTE-ELSRYYQRIGVILFINYLLEGGDIHFENL-IACNEYPVIIDAETFIGNIE----
--------------------------------------------G---------------
----------------------------------------DNGKSAT-------------
----------------------------------EKVSNLLRKSVLYS------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------GILDARI-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>NZ_ABYU02000049.1|c1|6852-9962|-|ZP_05855760.1|conserved_hypothetical_protein
------------------------------------------------------------
-MKKSSYLSERVYNV-------------------------------NPSEINMESLEYWK
K-----------------------------ILKEEGLQYVKKNHLEYFFG----------
------FLNNCSFSSHEKCQHQNFVEMSSKRE-------------------TCRHECDEM
IFGAFYDPFVQVA---NKQLRETV--------------TQKRYIKESILVDFQKSLF-NL
LNNLCIRTLIYE--MY-------ICGQEGL-----L----EGNEF--EQ---YQYYIDHF
LKDKQYLNDFFSLYPVLERRINEIIQNTIDIYKEVIERIDTDANEIMREF----N-----
---------IVESAFIVEHLSTDFS--DSHKNGRRVFCVEFV---SG-------EKILYK
PRCLQNEIKLQEITNYFYK-----------ICNLGS-YEYCILDKGKYGWCEIVT--QKD
CESTE-ELSRYYQRIGVILFINYLLEGGDIHFENL-IACNEYPVIIDAETFIGNIE----
----GDNGKSATEKVSNLLRKSVLYSGILPFYSWNNAGDA----GINMSAISGEEG-QKF
PIKIPFIINP-KSVNMR-VVYDYPVSKRN----HNLAM--LKGKFIQ-----PSEFADKI
IQGFKSAY-LG--AMEHTETLL---KIIQQYSE-LEVRYLIRNTQQYVIVLSSSYHPELL
MD---GGARNL-FFYSLI------NGNLQNENSKLLIEHEIEDLLSGDIPYFYFRGNKKS
IYT---WDGR--EVKN---FFSKTALQQIEENI-QYLSYKNLEQQIQYIKITF-------
-----NMENAGTRKIKNERLKPALSNNIFKT--AEELAKELLCKIGTNAIY------SED
GTDVNWIGV----KLFGIKENQWMIQA--LPNTLYDGTVGINLVFHLYERIYQDKK-YHE
---ICDVLD--NRIL----------RYIDTISDGK----KSIAEFNTGVF--CGEGSIL-
YAL----NILYEI-------YDDSKYKL-YFDKWLS----CMETIISEDCLF--------
--DLISGNSGIVLVLINM----YKKTG----TPTYLQKAIQIAEQL--------------
---------IEDMVTDKGKVGWKSEVVPEVL------AGFAHGNSGFIEMFSRLYEVYPQ
----A-----KYLR----VLSRLVEYENS-LYSEKNNNWT------DLRKFPEEDQNRDQ
PIAW-CHGAAGILLSRLTLYNAIKNSG---------ETA--LFQQVIKDISL-----AKN
KLIEDGL--------HAGF----CLCHGNMGNLLIL-KRYAE---IFDDK--QVRSICDS
RFEQILEFLNDQN------------VLPT-----ELYNPGFM--TGLSGIA-YALLK---
YTMPE-----LPLIIGVEGIDDRNKD---------------------------------
>NZ_AAYG02000011.1|c1|199754-201688|+|ZP_02040709.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MSAISGE------------------------------
------------------------------------------------------------
---------------------------------------------EG-------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------QKF
PIKIPFIINP-KSVNMR-VVYDYPVSKRN----HNLA-M-LKGKFIQ-----PSEFADKI
IQGFKSAY-LG--AMEHTETLL---KIIQQYSE-LEVRYLIRNTQQYVIVLSSSYHPELL
MD---GGARNL-FFYSLI------NGNLQNENSKLLIEHEIEDLLSGDIPYFYFRGNKKS
IYT---WDGR--EVKN---FFSKTALQQIEENI-QYLSYKNLEQQIQYIKITF-------
-----NMENAGTRKIKNERLKPALSNNIFKT--AEELAKELLCKIGTNAIY----S--ED
GTDVNWIGV---KLFG-IKENQWMIQA--LPNTLYDGTVGINLVFHLYERIYQDKK-YHE
-------IC--DVLD----NRIL--RYIDTISDGK----KSIAEFNTGVF--CGEGSIL-
YAL----NILYEI-------YDDSKYKL-YFDKWLS----CMETIISEDCLF--------
--DLISGNSGIVLVLINM----YKKTG----TPTYLQKAIQIAEQL--------------
---------IEDMVTDKGKVGWKSEVVPEVL------AGFAHGNSGFIEMFSRLYEVYPQ
----A-----KYLR----VLSRLVEYENS-LYSEKNNNWT------DLRKFPEEDQNRDQ
PIAW-CHGAAGILLSRLTLYNAIKNSG---------ETALFQQVIKDISLAKNK---LIE
DGLHAGF----------------CLCHGNMGNLLIL-KRYAE---IFDDK--QVRSICDS
RFEQILEFLNDQN------------VLPT-----ELYNPGFM--TGLSGIA-YALLK---
YTMPE-----LPLIIGVEGIDDRNKD---------------------------------
>NZ_AAMN01000001.1|c2|1157439-1158767|-|ZP_00994493.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSAAT--HDR----------
--------ELESAMPT--------------------DPASQDRERVLDAA----H-----
---------------------------------RCVDLL---------------------
-------------------------------------VRTAVIDRAGPTWPAWEL-----
------------------------------------------------------------
--------------------------------------------GADGQALG--------
-----------------------------------------------------------V
VAGRRSLY-DG-------------------------------------------------
------------DAGVVW-----------------------------ALTHLGTALHRPD
ATE-----------------LAASGARTLLQAR-----PTDLGAPAGLLVGEA-------
---------------------------------GVDLLARAGDRV---------------
-----------------AAGWS-------EGSDLTDGLAGILLSLARARRHESHAA----
-------------------------SIVAELRHRSRK---------------EGWGRSW-
------------------------------------------------------------
---------------------------PD------LRLPGDSARPL--------------
-------------------------------------CGLAHGASGIAWALVEAAGVWPR
--VAP-----AALE----LAGEALAWEAS-WSDPARGGWP----------DLREG-DVTW
PDLW-CHGAAGAGAVRL---RLLELAAAGLDLPWSLDTT-----RAEAEMAVQRCGAAMH
EATDQAV-----SHGVDAVAGGWTLCHGAGGPAGVV-ALAAD---VFGVPEHRERAVAAA
AAQVRVAPTDPEE---------WPSGLKG-----ADGDVSLA--TGVAGTA-MLLTD---
LAQPGT----VPSLVLLGLGGVRSTGEASALGGRGPGVVAADRG---------------
>NZ_GG670379.1|c1|120720-123704|+|ZP_05474920.1|predicted_protein
--------------------------------------------------------MNCF
EKGKALTIEERMSLIKNK----------------------------IFDDKNSSNIQRWL
N--------------------RKTTVDSELFSKILNINNWKLEEFNHCID----------
----------ENFKIDSYSDRVTYSDFDSLIA------------------SIEDQNNLPS
TYVKLIRPFLTKL---ENGLIVDF----------------QDKLSEKAIENIFDCLA-SR
LINLSLKVFVLE--MD-------FIKNSNG-----L----HGETS--KER--FINFIDL-
YDDKEKLLNLYQKYPVMTRKLSITTLYFIDFMNEFLNNLFQSWDSIEDTF----F-----
---------DTEEKIYVESLIFEKG--DTHEKGKSVVIIEFN---LG--------KIVYK
PRNLYIEKNFQKIIKFFSY----------SNGFLNM-DIPKSLYNSTFTFVQFIE--QEP
CNNEE-EIERFYQRYGQLIALIYLTNGSDIHFENV-ISHGEYPVIVDYETLFSVPI----
--KLEGRQENIFSEIVGVIRNSVSSSIMLPGKMQLDSEGN----SVDISGLSGKT--QKL
EKKMYVPKNL-DNDNAK-FVLENVILEGS----NNNV-F-YKDKLIN-----YQDYYKEI
IAGFSNVM-DF--FLVNKEEYL---NLIEGMEN-NTIRILARNTNTYAQFLEFTKHPNCL
KD---FVELEK-ILENLY--------TFPYENKQIS-QLEYKDMVFDDIPIFFSKLDENC
IYN---SEGV--RIQN---VFENTPRIFLIDKI-KNIDSENISKQIGIIMMKI-------
------------KGEEGVVKQDVSSLVISKEDSYLQIAEKLAEKLIDSAYI----D--KN
EEYMTWLVI------NDGVVDEFDLGA--SKVNFYDGLIGIASLFKSLYKVTGKVK-YQR
-------YF--DYLV----KTTM--DLLDTMQTDS-------------AY--VGFHSFL-
--------QLFSI-------IEKEDTNYERITHYLN----LLQQNSQNFLEREGTV----
--DWLLGYGGIIPLYIDV----YKKTK----DNQYLEIAIFLGNKL--------------
---------IMFAEKDTNVMKN---------------IGIGHGISGLLISMVELYKVTKD
----R-----QYLE----YIKKLNERMSI-----------------------SLVQENED
VVSW-CNGILGYLLGQS---YLHKNNI---------KSA-----LSDKEKQR-----LLL
KIKNQYL---------ESD----CLCHGNCGIIQFY-IDLYL---LENSD--KYLEHAKK
IGNKMISEIIKNE--------YIQIREFE-----GFDNIGLF--NGISGVA-YTLVR---
LLEPEN----VPSVFV-------------------------------------------
>NZ_GG730158.1|c1|632782-635871|+|ZP_06329064.1|predicted_protein
---------------------------------------------------MNQMLLNNQ
EFVEALTIKERIELFKEMEEDYFN----------------------YDQEIIDSIFMEWI
N--------------------RKSSLKMEDFDEIITNQGYDYRYYKYVIS----------
--------QKYNYLLATSLNNKIWYKNINTII---------------DSHYSSHAASEEI
GYYLIYNPFLEKA---KDELYEYL---------QKSNEKLEIFNSKTLLKEFYEHIA-QL
MFNISNKAIITE--LH-------EQKSQGF-----L----KGRNE--KEE--LKYFLTN-
ISQKDNIIKFFNKYPVLCRKLYQVYKTQVDYMIALLQNIINDWSDIIEVF----------
----------GLKNEKLMSIHFGQG--DTHQDGKTVAILHFG---DS-------NKIVYK
PKNLHIAKLYNTLVNFLNK----------ENQFLDL-KYANILMKENYSYEEFIT--NSD
AKSLK-EVNNYYYRYGQIMGICYLLNASDIHFENI-ISSRDMPHVIDLETLFFNVI----
--PRVGMSDDVQLKAQEIILNNIDNTLLIPIELQLDSRGS----KVDFSGLSYET--QEI
SKKRYVLNNI-DNSNVK-YVESNIVIPQS----KNVVR--HQNEIID-----YKDFIENI
IEGFKCTC-AI--VMKKKDCII---KIIDDYKN-QIIRVIPRSTDKYVQFLQYTYHPSAL
KS---YLNLES-ILENLY--------ALPFKERKII-KSEYYDLLNGDVPVFFSRIDSKD
IID---SKGR--FINN---VYFRSNYSLVHDKI-NSLDNSICANQIAIVQSSI-------
---------NTLPDNDIDGFFIKDEKVNDKE--ILEIIEVTLESILGKGII--------Y
KDLITWIDM--------LQDGSGNKKPKILNTNLYDGISGISLVLVYIKKIYPEK--FDR
-------YM--ELTL----------NNSINRPNVD--------YSAISAY--NGFASNI-
YPI------LKHM---------DGSFRGKRYKRVLT----QFINSLESFEEKDINNY---
--DWLSGIGSLPSLINHI----YNMLP----DGHLLNILNKFADIL--------------
------------IRQKIEVFAIDN-------------LGLAHGLSGYLLSLKNVNLNIER
----E-----DVQN----LILEIEEKLIK-SYDSNLSGWK-----------FKRNKEMIC
TNYW-CTGSIGIALSLS---HLVSKKN---------EEK------INEIQKD-----LEE
YYIDTNK-------LLRSD----TLCHGNLGVIDYL-IYRYN---ITGNE--ILLEKAKK
IFSNIIRKQKKYG--------HYSLNSYG-----EYPSTSLF--TGKLGLC-YIGLR---
LLNPET----IDSVSILE-----------------------------------------
>NZ_GG730336.1|c2|603444-606533|+|ZP_06340736.1|predicted_protein
---------------------------------------------------MNQMLLNNQ
EFVEALTIKERIELFKEMEEDYFN----------------------YDQEIIDSIFMEWI
N--------------------RKSSLKMEDFDEIITNQGYDYRYYKYVIS----------
--------QKYNYLLATSLNNKIWYKNINTII---------------DSHYSSHAASEEI
GYYLIYNPFLEKA---KDELYEYL---------QKSNEKLEIFNSKTLLKEFYEHIA-QL
MFNISNKAIITE--LH-------EQKSQGF-----L----KGRNE--KEE--LKYFLTN-
ISQKDNIIKFFNKYPVLCRKLYQVYKTQVDYMIALLQNIINDWSDIIEVF----------
----------GLKNEKLMSIHFGQG--DTHQDGKTVAILHFG---DS-------NKIVYK
PKNLHIAKLYNTLVNFLNK----------ENQFLDL-KYANILMKENYSYEEFIT--NSD
AKSLK-EVNNYYYRYGQIMGICYLLNASDIHFENI-ISSRDMPHVIDLETLFFNVI----
--PRVGMSDDVQLKAQEIILNNIDNTLLIPIELQLDSRGS----KVDFSGLSYET--QEI
SKKRYVLNNI-DNSNVK-YVESNIVIPQS----KNVVR--HQNEIID-----YKDFIENI
IEGFKCTC-AI--VMKKKDCII---KIIDDYKN-KIIRVIPRSTDKYVQFLQYTYHPSAL
KS---YLNLES-ILENLY--------ALPFKERKII-KSEYYDLLNGDVPVFFSRIDSKD
IID---SKGR--FINN---VYFRSNYSLVHDKI-NSLDNSICANQIAIVQSSI-------
---------NTLPDNDIDGFFIKDEKVNDKE--ILEIIEVTLESILGKGII--------Y
KDLITWIDM--------LQDGSGNKKPKILNTNLYDGISGISLVLVYIKKIYPEK--FDR
-------YM--ELTL----------NNSINRPNVD--------YSAISAY--NGFASNI-
YPI------LKHM---------DGSFRGKRYKRVLT----QFINSLESFEEKDINNY---
--DWLSGIGSLPSLINHI----YNMLP----DGHLLNILNKFADIL--------------
------------IRQKTEVFAIDN-------------LGLAHGLSGYLLSLKNVNLNIER
----E-----DVQN----LILEIEEKLIK-SYDSNLSGWK-----------FKRNKEMIC
TNYW-CTGSIGIALSLS---HLVSKKN---------EEK------INEIQKD-----LEE
YYIDTNK-------LLRSD----TLCHGNLGVIDYL-IYRYN---ITGNE--ILLEKAKK
IFSNIIRKQKKYG--------HYSLNSYG-----EYPSTSLF--TGKLGLC-YIGLR---
LLNPKT----IDSVSILE-----------------------------------------
>NZ_GG730274.1|c2|605972-609061|+|ZP_06310555.1|conserved_hypothetical_protein
---------------------------------------------------MNQMLLNNQ
EFVEALTIKERIELFKEMEEDYFN----------------------YDQEIIDSIFMEWI
N--------------------RKSSLKMEDFDEIITNQGYDYRYYKYVIS----------
--------QKYNYLLATSLNNKIWYKNINTII---------------DSHYSSHAASEEI
GYYLIYNPFLEKA---KDELYEYL---------QKSNEKLEIFNSKTLLKEFYEHIA-QL
MFNISNKAIITE--LH-------EQKSQGF-----L----KGRNE--KEE--LKYFLTN-
ISQKDNIIKFFNKYPVLCRKLYQVYKTQVDYMIALLQNIINDWSDIIEVF----G-----
-----------LKNEKLMSIHFGQG--DTHQDGKTVAILHFG---DS-------NKIVYK
PKNLHIAKLYNTLVNFLNK----------ENQFLDL-KYANILMKENYSYEEFIT--NSD
AKSLK-EVNNYYYRYGQIMGICYLLNASDIHFENI-ISSRDMPHVIDLETLFFNVI----
--PRVGMSDDVQLKTQEIILNNIDNTLLIPIELQLDSRGS----KVDFSGLSYET--QEI
SKKRYVLNNI-DNSNVK-YVESNIVIPQS----KNVV-R-HQNEIID-----YKDFIENI
IEGFKCTC-AI--VMKKKDCII---KIIDDYKN-QIIRVIPRSTDKYVQFLQYTYHPSAL
KS---YLNLES-ILENLY--------ALPFKERKII-KSEYYDLLNGDVPVFFSRIDSKD
IID---SKGR--FINN---VYFRSNYSLVHDKI-NSLDNSICANQIAIVQSSI-------
---------NTLPDNDIDGFFIKDEKVNDKE--ILEIIEVTLESILGKGII--------Y
KDLITWIDM--------LQDGSGNKKPKILNTNLYDGISGISLVLVYIKKIYPEK--FDR
-------YM--ELTL----------NNSINRPNVD--------YSAISAY--NGFASNI-
YPI------LKHM---------DGSFRGKRYKRVLT----QFINSLESFEEKDINNY---
--DWLSGIGSLPSLINHI----YNMLP----DGHLLNILNKFADIL--------------
------------IRQKTEVFAIDN-------------LGLAHGLSGYLLSLKNVNLNIER
----E-----DVQN----LILEIEEKLIK-SYDSNLSGWK-----------FKRNKEMIC
TNYW-CTGSIGIALSLS---HLVSKKN---------EEK-----INEIQKDL------EE
YYIDTNK-------LLRSD----TLCHGNLGVIDYL-IYRYN---ITGNE--ILLEKAKK
IFSNIIRKQKKYG--------HYSLNSYG-----EYPSTSLF--TGKLGLC-YIGLR---
LLNPKT----IDSVSILE-----------------------------------------
>NZ_GG730183.1|c2|412465-415554|+|ZP_06325849.1|predicted_protein
---------------------------------------------------MNQMLLNNQ
EFVEALTIKERIELFKEMEEDYFN----------------------YDQEIIDSIFMEWI
N--------------------RKSSLKMEDFDEIITNQGYDYRYYKYVIS----------
--------QKYNYLLATSLNNKIWYKNINTII---------------DSHYSSHAASEEI
GYYLIYNPFLEKA---KDELYEYL---------QKSNEKLEIFNSKTLLKEFYEHIA-QL
MFNISNKAIITE--LH-------EQKSQGF-----L----KGRNE--KEE--LKYFLTN-
ISQKDNIIKFFNKYPVLCRKLYQVYKTQVDYMIALLQNIINDWSDIIEVF----------
----------GLKNEKLMSIHFGQG--DTHQDGKTVAILHFG---DS-------NKIVYK
PKNLHIAKLYNTLVNFLNK----------ENQFLDL-KYANILMKENYSYEEFIT--NSD
AKSLK-EVNNYYYRYGQIMGICYLLNASDIHFENI-ISSRDMPHVIDLETLFFNVI----
--PRVGMSDDVQLKAQEIILNNIDNTLLIPIELQLDSRGS----KVDFSGLSYET--QEI
SKKRYVLNNI-DNSNVK-YVESNIVIPQS----KNVVR--HQNEIID-----YKDFIENI
IEGFKCTC-AI--VMKKKDCII---KIIDDYKN-QIIRVIPRSTDKYVQFLQYTYHPSAL
KS---YLNLES-ILENLY--------ALPFKERKII-KSEYYDLLNGDVPVFFSRIDSKD
IID---SKGR--FINN---VYFRSNYSLVHDKI-NSLDNSICANQIAIVQSSI-------
---------NTLPDNDIDGFFIKDEKVNDKE--ILEIIEVTLESILGKGII--------Y
KDLITWIDM--------LQDGSGNKKPKILNTNLYDGISGISLVLVYIKKIYPEK--FDR
-------YM--ELTL----------NNSINRPNVD--------YSAISAY--NGFASNI-
YPI------LKHM---------DGSFRGKRYKRVLT----QFINSLESFEEKDINNY---
--DWLSGIGSLPSLINHI----YNMLP----DGHLLNILNKFADIL--------------
------------IRQKTEVFAIDN-------------LGLAHGLSGYLLSLKNVNLNIER
----E-----DVQN----LILEIEEKLIK-SYDSNLSGWK-----------FKRNKEMIC
TNYW-CTGSIGIALSLS---HLVSKKN---------EEK------INEIQKD-----LEE
YYIDTNK-------LLRSD----TLCHGNLGVIDYL-IYRYN---ITGNE--ILLEKAKK
IFSNIIRKQKKYG--------HYSLNSYG-----EYPSTSLF--TGKLGLC-YIGLR---
LLNPKT----IDSVSILE-----------------------------------------
>NZ_ACOK01000098.1|c1|8746-11682|-|ZP_06143782.1|lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKLNEIHDIIDNVL-------------PVGENTLKVTGFYDK
MFGSFYEPFTEYF---LRKLDTAL---------DDIGAGGYLVDREAFMLNSAGYFL-TD
QASLALSTLIIE--IN-------ERKESGV-----Y----DSDDI-------YSNFYED-
MRSAETIKAFAAKYPCLYDIIFHNADERVQLITDCLRGMIGHKDEIMETF----G-----
-----------FDCTQTGDLSISSG--DSHNGGKKVVIVKGP---SG--------TLVYK
PHALAPELLFEKVRDIVME---------KGKVKYSL-DTAKVLSCGDYGFQEFIR--QKP
VSTEE-EACRYYYRIGAFSAVFNALRCDDLHYENI-VCAGERPYFVDLETLVKNNS----
KESDTKNYPPFLRDVLSTFEDSVLGTMMYPMNSSFVFF------DFDMGGISGSPKQTSK
KWKSYSLCNE-GTDRIC-ITSGEGRLSEA----NNLL-Y-CNGKEVL-----PIYFAEEM
IQGYQDAM-NA--VIASKAQII---DAMKSSEG--TIRRVLRPTAMYGKFLQVASSPLYY
RD---KTARVK-LFSKLY---KGIDQSPREFSRVSC---EVEALMNNDIPFFEQKLNGKD
IIA---NHNY--TISD---YNTSSPSDGVEQFI-GKIDEDYIRRQTMLIRMSL-------
----ASSYNSKAEGEVFGRELPREKFALDSD--MTRAAEMIGEQLLSSALQ----A--KE
SDSISWFTE--------SLIDNIKLDV--LDVKMYDG-GGTVMLFLYLWKYTGREK-WLR
-------AA--ENVM----------SGAEELGYTK-------PKADVSFF--TGAAGLV-
YLW----YNFFAL-------TGDTSYVD-KINSYLK----ECLVKMKESPDDIRD-----
--DIIAGAAGTLVALSRM----NRQLRLDVIDEILEISAEHLAERF--------------
--------EKGETEVM---------------------TGFAHGYAGIALAFAEYGDYTGD
----E-----RYTA----LAAKAVDMENK-YFCEDEKNWK------------DLRDKGGF
GSFW-CHGAPGIGLARL---MMKKLRG-------FENNE-----TISEDILR-----GVH
ILLREGF------ASDMDH----SLCHGTFGTMDML-LTYAN---AIGSS--ELRETAVS
AAGRYMNEIEKEG---------FKAGIKG-----MSATPSGM--TGITGVA-YTLMR---
LAHPE-----MPALNSIEIPEIRRTDSGSAEHTDSEIYAFAVS----------------
>NZ_ABAG01000003.1|c1|150701-152701|+|ZP_01834979.1|lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MSKNYPIVIDSETLFTNPDLSCN
RNSTIQNPETVHDLFQKFIKDSVLDTLLLPNNFQSSLF------DFDLSPLTNYQQ-LSE
NITRFTIEND-FSHNIH-LKEVHVVLPSS-------------NVKKE-----TNKFYGKI
IDGFKACY-TI--LENSKNYFIEEIKLLSEKYP-LYLRQVLRPTMVYVKFLEASTHPDYL
TD----IKKQRKLFQKLN----SSLYKLDSTLGKQV-EIEINSLMKGDVPYFYTKFNSLS
IYS---------MENKICNFYATSIQSKLLERF-QKLGNKDMLKQLHVIFLSL-------
------STVKDTTFSDINQSPLHDFIIPVND--ENSLVLKVGDYVNHQVVW-------NN
NNEFCILPS---VT---QIDDKKVILP--VSYCLYDG-GGVVLLLYYLYLKFNEEK-YKI
-------VA--DGLL----------KGFESMIEIE-------TNRNFSAF--NGIGSVI-
YIY--IYYCLFIL-------TSEPDYHE-----KYK----FYLAMLEKQDIPLDQPI---
--DFL-GISSLIILLCNI----YKIEHSSKLFTLLKKCINYCISQL--------------
--------DNITV------------------------TGLAHGYSGVAMSLSYYYEINPS
----T-----DILK----CIEELLYKEDK-FFNNILKNWK----------DIRRNHNDSF
PNFW-CYGAPGILLARK---EIFDKTN-----------------IGNNDLSI------IE
NVLTNVE-------KIREL----NLCHGSVGTISCL-DAILK-----DEENLLIKESIDF
YFDNVVSQVIKPE---------LSTDLN------TMNTFSFM--LGVSGVV-YEISR---
-KQDDR----LLNVLLLELKRT-------------------------------------
>NZ_ACPD01000003.1|c1|12574-15420|-|ZP_04803845.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MEKLFGNYIKKSFEIKEINKIV---------------HRTKEYFGEFSRY
YLYIFYYEFDNAIIRKYGDLFDQF---------------------NSIIQQQLDIFF-KD
IFYISIRVLIVE--MN-------IMKDENK-----L----VGANS--QER--YLYYSEL-
LTKEEYIDYLISKYPVLNRILLEKCKNQIRLINECLSNYIQDFEPMCETF----E-----
---------ISAQSKIKQ-IIVTSG--DSHNGGKKVILLELS---EN--------KILYK
PHDFSSEKIFNEILESINK---------EQCIKYKL-KTIKNITRDNYAWQDYIK--AIG
CTKIQ-EVEEYYYKIGAYLAVLYSLGCEDIHKENI-IASGNNPYLIDMETLSNCQA----
--PLINDKATMLEHFFYENSQSVFGTMLLPTNSAVSIF------DYDIGGISGDDNIETS
KWEAFDIKNQ-GTDNLQ-FVKESKFITGG----CDNIVK-LNGEATR-----ARDYYKNI
IEGFSDCY-KI--FIKTPNKVV---DILKESE--VIIRQVLRPTAVYSKFLEASTYPTYL
TN---EESFRG-LFAKLD-------NLEEVKEKKKA-QIEIDSLYEFDIPYFYSDLNTTN
IYS----VKG--KVDN---YINYSVMDAISGKA-RKFSEKDLKVQIYYINLAL-------
----STQPNTSEMIYKYNLFSK-SQNLKNIT--INHIAKQIGDVIEEKLIW-------DY
RKQSCFFMI---DT---VVKEKRKYCS--MDSSLY-GSGGVILYYLSLYKATCDLK-YKH
-------IV--EGLI----NGHI--GLHSKKSLEE----------GIGLF--SGLTSLA-
YIY----YQCYRV-------LGKKQYLE-DVLEVLK----EIEENLHMWDEL--------
--DLSTGLSGVIIFLSEL----YKTE-NN--EQY-LLIANGLADKLYKLVLK--------
--------ANFNML-----------------------TGLAHGYAGVAWALYSIGHIVNN
----E-----DYIN----CAMKCIEEENM-YYDSEKNNWK------------DKRNGSSE
SFYW-CYGAFGIGIARL---KMYEIAH---------NDI-----LLK-DIEK-----CRY
IYINYNL----INSK-YNH----SLCHGLTGNLSAIKMFSDF---YKNDN--KLKKKYKE
MLDILLNDVVNGK---------VIWGDKE-----LIEDYSFM--IGLSGIG-YELLR---
HEATN-----SVNILALEV----------------------------------------
>NZ_ACMO01000224.1|c1|850-3903|+|ZP_04206897.1|Bacteriocin_formation_protein
---------------------------------------------------------MLT
NLHKSLNIRERYDLMSTYIK--------------------------DSKEYNSDALSNWR
T--------------------EMSILSDEEFEQMLKYNDYKMNAFSFAVD----------
----KNPSEEINNLYKQKAKESQWYNTFIEIM--------------ENTDLNEVLDPERA
GMLFILRPFIDFV---KKEISIFV-----------SKHDYHSIVSQNILESLIEQFA-IS
IAEVAQKSLVLE--LN-------LDRENEF-----L----VGTTP--EDR--FVFFVNQ-
YKDKDKLIDFFDKYIVLTRLLSTITPNFISNIKVLFNRIDKHKNDILQTF----T-----
----------IEVPLLLTDIKIGQG--DTHNKGNTVIELIFN---KN-------YKIIYK
PKNLEISKLYNEIIEYFNK----------KDDVLDM-KIVKGIYEDDYSFEEFIP--YEQ
CHNKV-QLAHYYERFGQVMAILYLLNASDMHLENL-IANGEYPVAIDLETLFQQPI----
--MHALDEYPILKKARLQMFNNVVSTMLLPHGTRSDREDEV---GIDLSALDGKG--VKI
NKKILQPVNI-GTDEMR-YEHLEFKTSDS----NNIPYLETVNNKVG-----YKDYIIEI
INGFRNVC-SI--ALNNKKDLI---ELCNDSGN-KIARVIVRDTSQYGNILQHSHHPDLL
QD---MLDREK-VLENMW--------THSFSNKEII-KHEIEDMLINDIPIFFNKIGTKD
VIS---SNGE--LMLS---IQQYDGKELVINKV-NNLTEDEINKQVSVMNISF-------
------GLYPEKEQMQKQPKLLQQNTFGEFD--LKEEAIRIADDILQNAIV--------E
EDKIMWIAV------NPEEGDKWSIGL--IDDDFYDGLSGVYLFLHTLYVETQKEE-YLD
-------YA--NRVL----------KTLNHHVVKN----------ELGMN--SSSIGIM-
HAV----SRIKNK-------KLSRALRE-ELKNQVN----YIDDQEIDITHT--------
--DYLNGSISLVNTLINI----YENGK----DANYLSLAIKYAEKY--------------
---------IKLPIKEKINND----------------ISFGHGYISIALVFFRLWKCTNN
----Q-----RYYNLGGDFYNEFYASFEE----------------------HKKEEFKDL
NFSW-CRGILGILIAEL---EIMNILD---------NEK-------HSSVVE-----ALE
PLLLNMD-------MSGND----GLCHGNIAVTEYF-LKKYE---YSNNE--EDLKMAQI
IVQNIINRHNREN--------RFMLRYAK-----GFKSIGLF--TGLSGIG-YQMLR---
VSNPEK----IKSILD-------------------------------------------
>NZ_ABAF01000008.1|c1|56524-58455|-|ZP_01833492.1|bacteriocin_formation_protein,_putative
------------------------------------------------------MKYKIK
NVHKTLFIKERYQILSER----------------------------NDNSLNNFSLNNWR
S--------------------TMSIISEKTFEEMLKLNNYNKKIFSNTVN----------
----YDYTEEQIRLYSEYAKNSEWYKFAEGSF--------------EIFRKHPQRINFKK
DFSRILEPFIINL---LKLINNYL----------ENKEYEWIDKNGNIFSSLVFYLE-DL
IYPWIVKPLVLE--IN-------SLREKGL-----L----EGESE--QQR--YKYFITL-
FDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEEL----G-----
------------LRGKLNDIKFGKG--DTHSQGKTVLILFF----DD-------AKIVYK
PKNLIINNSLNTIAEYIRK----------VDEKIRI-RIPRTIAYSDHSYEEFID--YLP
LEQKK-KLPEYYYNFGVLLAFIYLFNGSDIHFENL-ISYGDMPVIIDFETMLQQPL----
------FDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGL----DVEMSALTGNF--KKD
AFNGQVLINL-NTDKVK-FDIGKIDFEGG----KNLP---VRDGDIE-----FDKYIKDF
KKGFRDFY-LIFEELNKTEEFK--MLLKANLYG-LKTRVLFRDTNSYASVLSFLYHPDFY
EE---MLDREK-ALENLW--------SNKFSNQGIV-ASECEQMRLLDIPIFYTDTNINE
IYD---DFGN--HFIS---LHQFSGYDYFMKYL-PNNNLENLEKQLDIIEIYF-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------PSFDQRKKGYKLNLS--------
----------NRKK----------------------------------------------
------------------------------------TPK---------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>NZ_ABAF01000008.1|c1|55464-56474|-|ZP_01833491.1|bacteriocin_formation_protein,_putative
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MVINNIYDEYPI--------------------------------------------
------------------------------------------------------------
-------------------------------------------------WSIPVN-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------FKGSKWCLEQ--TGNDMYRGRAGILLFMYYVKLLKDKSS-YTQ
-------LY--NKML----SAIPPSVSLSKTT--------------------FGLTGDIG
YFI------VLSI-------IEDYDTNTLACLNYIK----SVLTELEKTDFASVSNKS--
--DYINGLLPLINTLVRY----YRRGIE---KERVLRLVLSLGDTL--------------
--------YNDVSERDNSNFG----------------YSFGHGLSGVIFTLKNIYKVTRL
----K-----KYKE----LILQLVPREKI----------------------------KIH
SLKW-CSGEFGTLVN---------------------HPQ------------------SVP
EGIVASL---------DND----TFCHGSMAIINFY-IDYMK---EMDTS-----MELES
LLCSVVMNKSKEG--------EYRIVQTS-----NFPDFSLY--TGVTGIA-YTFLRYIA
LNQNDKKIV-IPSLLEI------------------------------------------
>NC_003098.1|c3|1732567-1735557|+|NP_359359.1|bacteriocin_formation_protein,_putative
------------------------------------------------------MKYKIK
NVHKTLFIKERYQILSER----------------------------NDNSLNNFSLNNWR
S--------------------TMSIISEKTFEEMLKLNNYNKKIFSNTVN----------
----YDYTEEQIRLYSEYAKNSEWYKFAEGSF--------------EIFRKHPQRINFKK
DFSRILEPFIINL---LKLINNYL----------ENKEYEWIDKNGNIFSSLVFYLE-DL
IYPWIVKPLVLE--IN-------SLREKGL-----L----EGESE--QQR--YKYFITL-
FDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEEL----------
-----------GLRGKLNDIKFGKG--DTHSQGKTVLILFF----DD-------AKIVYK
PKNLIINNSLNTIAEYIRK----------VDEKIRI-RIPRTIAYSDHSYEEFID--YLP
LEQKK-NLPEYYYNFGVLLAFIYLFNGSDIHFENL-ISYGDMPVIIDFETMLQQPL----
------FDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGL----DVEMSALTGNF--KKD
AFNGQVLINL-NTDKVK-FDIGKIDFEGG----KNLP---VRDGDIE-----FNKYIKDF
KKGFRDFY-LIFEELHKTEEFK--MLLKANLYG-LKTRVLFRDTNSYASVLSFLYHPDFY
EE---MLDREK-ALENLW--------SNKFSNQGIV-ASECEQMRLLDIPIFYTDTNINE
IYD---DFGN--HFIS---LHQFSGYDYFMKYL-PNNNLENLEKQLDIIEIYF-------
---PSFDQRKKGYKLNLSNRKKLPNESLVTI--LHNEVENIADSLVINNIY---------
DEYPIW------SIPVNFKGSKWCLEQ--TGNDMYRGRAGILLFMYYVKLLKDKSS-YTQ
-------LY--NKML----SAIPPSVSLSKTT--------------------FGLTGDIG
YFI------VLSI-------IEDYDTNTLACLNYIK----SVLTELEKTDFASVSNKS--
--DYINGLLPLINTLVRY----YRRGIE---KERVLRLVLSLGDTL--------------
--------YNDVSERDNSNFG----------------YSFGHGLSGVIFTLKNIYKVTRL
----K-----KYKE----LILQLVPREKI----------------------------KIH
SLKW-CSGEFGTLVN---------------------HPQ------------------SVP
EGIVASL---------DND----TFCHGSMAIINFY-IDYMK---EMDTS-----MELES
LLCSVVMNKSKEG--------EYRIVQTS-----NFPDFSLY--TGVTGIA-YTFLRYIA
LNQNDKKIV-IPSLLEI------------------------------------------
>NC_011900.1|c3|1908536-1911526|+|YP_002511832.1|putative_lantibiotic_modifying_enzyme
------------------------------------------------------MKYKIK
NVHKTLFIKERYQILSER----------------------------NDNSLNNFSLNNWR
S--------------------TMSIISEKTFEEMLKLNNYNKKIFSNTVN----------
----YDYTEEQIRLYSEYAKNSEWYKFAEGSF--------------EIFRKHPQRINFKK
DFSRILEPFIINL---LKLINNYL----------ENKEYEWIDKNGNIFSSLVFYLE-DL
IYPWIVKPLVLE--IN-------SLREKGL-----L----EGESE--QQR--YKYFITL-
FDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEEL----------
-----------GLRGKLNDIKFGKG--DTHSQGKTVLILFF----DD-------AKIVYK
PKNLIINNSLNTIAEYIRK----------VDEKIRI-RIPRTIAYSDHSYEEFID--YLP
LEQKK-KLPEYYYNFGVLLAFIYLFNGSDIHFENL-ISYGDMPVIIDFETMLQQPL----
------FDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGL----DVEMSALTGNF--KKD
AFNGQVLINL-NTDKVK-FDIGKIDFEGG----KNLP---VRDGDIE-----FDKYIKDF
KKGFRDFY-LIFEELNKTEEFK--MLLKANLYG-LKTRVLFRDTNSYASVLSFLYHPDFY
EE---MLDREK-ALENLW--------SNKFSNQGIV-ASECEQMRLLDIPIFYTDTNINE
IYD---DFGN--HFIS---LHQFSGYDYFMKYL-PNNNLENLEKQLDIIEIYF-------
---PSFDQRKKGYKLNLSNRKKLPNESLVTI--LHNEVENIADSLVINNIY---------
DEYPIW------SIPVNFKGSKWCLEQ--TGNDMYRGRAGILLFMYYVKLLKDKSS-YTQ
-------LY--NKML----SAIPPSVSLSKTT--------------------FGLTGDIG
YFI------VLSI-------IEDYDTNTLACLNYIK----SVLTELEKTDFASVSNKS--
--DYINGLLPLINTLVRY----YRKGIE---KERVLRLVLSLGDTL--------------
--------YNDVSERDNSNFG----------------YSFGHGLSGVIFTLKNIYKVTRL
----K-----KYKE----LILQLVPREKI----------------------------KIH
SLKW-CSGEFGTLVN---------------------HPQ------------------SVP
EGIVASL---------DND----TFCHGSMAIINFY-IDYMK---EMDTS-----MELES
LLCSVVMNKSKEG--------EYRIVQTS-----NFPDFSLY--TGVTGIA-YTFLRYIA
LNQNDKKIV-IPSLLEI------------------------------------------
>NZ_ABGF01000008.1|c1|60195-63185|-|ZP_02716217.1|CylM_protein,_cytolytic_toxin_system
------------------------------------------------------MKYKIK
NVHKTLFIKERYQILSER----------------------------NDNSLNNFSLNNWR
S--------------------TMSIISEKTFEEMLKLNNYNKKIFSNTVN----------
----YDYTEEQIRLYSEYAKNSEWYKFAEGSF--------------EIFRKHPQRINFKK
DFSRILEPFIINL---LKLINNYL----------ENKEYEWIDKNGNIFSSLVFYLE-DL
IYPWIVKPLVLE--IN-------SLREKGL-----L----EGESE--QQR--YKYFITL-
FDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEEL----------
-----------GLRGKLNDIKFGKG--DTHSQGKTVLILFF----DD-------AKIVYK
PKNLIINNSLNTIAEYIRK----------VDEKIRI-RIPRTIAYSDHSYEEFID--YLP
LEQKK-KLPEYYYNFGVLLAFIYLFNGSDIHFENL-ISYGDMPVIIDFETMLQQPL----
------FDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGL----DVEMSALTGNF--KKD
AFNGQVLINL-NTDKVK-FDIGKIDFEGG----KNLP---VRDGDIE-----FDKYIKDF
KKGFRDFY-LIFEELNKTEEFK--MLLKANLYG-LKTRVLFRDTNSYASVLSFLYHPDFY
EE---MLDREK-ALENLW--------SNKFSNQGIV-ASECEQMRLLDIPIFYTDTNINE
IYD---DFGN--HFIS---LHQFSGYDYFMKYL-PNNNLENLEKQLDIIEIYF-------
---PSFDQRKKGYKLNLSNRKKLPNESLVTI--LHNEVENIADSLVINNIY---------
DEYPIW------SIPVNFKGSKWCLEQ--TGNDMYRGRAGILLFMYYVKLLKDKSS-YTQ
-------LY--NKML----SAIPPSVSLSKTT--------------------FGLTGDIG
YFI------VLSI-------IEDYDTNTLACLNYIK----SVLTELEKTDFASVSNKS--
--DYINGLLPLINTLVRY----YRRGIE---KERVLRLVLSLGDTL--------------
--------YNDVSERDNSNFG----------------YSFGHGLSGVIFTLKNIYKVTRL
----K-----KYKE----LILQLVPREKI----------------------------KIH
SLKW-CSGEFGTLVN---------------------HPQ------------------SVP
EGIVASL---------DND----TFCHGSMAIINFY-IDYMK---EMDTS-----MELES
LLCSVVMNKSKEG--------EYRIVQTS-----NFPDFSLY--TGVTGIA-YTFLRYIA
LNQNDKKIV-IPSLLEI------------------------------------------
>NZ_ABFS01000011.1|c1|21729-24719|+|ZP_02709201.1|CylM_protein,_cytolytic_toxin_system
------------------------------------------------------MKYKIK
NVHKTLFIKERYQILSER----------------------------NDNSLNNFSLNNWR
S--------------------TMSIISEKTFEEMLKLNNYNKKIFSNTVN----------
----YDYTEEQIRLYSEYAKNSEWYKFAEGSF--------------EIFRKHPQRINFKK
DFSRILEPFIINL---LKLINNYL----------ENKEYEWIDKNGNIFSSLVFYLE-DL
IYPWIVKPLVLE--IN-------SLREKGL-----L----EGESE--QQR--YKYFITL-
FDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEEL----------
-----------GLRGKLNDIKFGKG--DTHSQGKTVLILFF----DD-------AKIVYK
PKNLIINNSLNTIAEYIRK----------VDEKIRI-RIPRTIAYSDHSYEEFID--YLP
LEQKK-NLPEYYYNFGVLLAFIYLFNGSDIHFENL-ISYGDMPVIIDFETMLQQPL----
------FDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGL----DVEMSALTGNF--KKD
AFNGQVLINL-NTDKVK-FDIGKIDFEGG----KNLP---VRDGDIE-----FDKYIKDF
KKGFRDFY-LIFEELNKTEEFK--MLLKANLYG-LKTRVLFRDTNSYASVLSFLYHPDFY
EE---MLDREK-ALENLW--------SNKFSNQGIV-ASECEQMRLLDIPIFYTDTNINE
IYD---DFGN--HFIS---LHQFSGYDYFMKYL-PNNNLENLEKQLDIIEIYF-------
---PSFDQRKKGYKLNLSNRKKLPNESLVTI--LHNEVENIADSLVINNIY---------
DEYPIWSIP------VNFKGSKWCLEQ--TGNDMYRGRAGILLFMYYVKLLKDKSS-YTQ
-------LY--NKML----SAIPPSVSLSKTT--------------------FGLTGDIG
YFI------VLSI-------IEDYDTNTLACLNYIK----SVLTELEKTDFASVSNKS--
--DYINGLLPLINTLVRY----YRRGIE---KERVLRLVLSLGDTL--------------
--------YNDASERDNSNFG----------------YSFGHGLSGVIFTLKNIYKVTRL
----K-----KYKE----LILQLVPREKI----------------------------KIH
SLKW-CSGEFGTLVN---------------------HPQ------------------SVP
EGIVASL---------DND----TFCHGSMAIINFY-IDYMK---EMDTS-----MELES
LLCSVVMNKSKEG--------EYRIVQTS-----NFPDFSLY--TGVTGIA-YTFLRYIA
LNQNDKKIV-IPSLLEI------------------------------------------
>NC_003028.3|c3|1850902-1853892|+|NP_346378.1|bacteriocin_formation_protein,_putative
------------------------------------------------------MKYKIK
NVHKTLFIKERYQILSER----------------------------NDNSLNNFSLNNWR
S--------------------TMSIISEKTFEEMLKLNNYNKKIFSNTVN----------
----YDYTEEQIRLYSEYAKNSEWYKFAEGSF--------------EIFRKHPQRINFKK
DFSRILEPFIINL---LKLINNYL----------ENKEYEWIDKNGNIFSSLVFYLE-DL
IYPWIVKPLVLE--IN-------SLREKGL-----L----EGESE--QQR--YKYFITL-
FDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEEL----------
-----------GLRGKLNDIKFGKG--DTHSQGKTVLILFF----DD-------AKIVYK
PKNLIINNSLNTIAEYIRK----------VDEKIRI-RIPRTIAYSDHSYEEFID--YLP
LEQKK-NLPEYYYNFGVLLAFIYLFNGSDIHFENL-ISYGDMPVIIDFETMLQQPL----
------FDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGL----DVEMSALTGNF--KKD
AFNGQVLINL-NTDKVK-FDIGKIDFEGG----KNLP---VRDGDIE-----FDKYIKDF
KKGFRDFY-LIFEELNKTEEFK--MLLKANLYG-LKTRVLFRDTNSYASVLSFLYHPDFY
EE---MLDREK-ALENLW--------SNKFSNQGIV-ASECEQMRLLDIPIFYTDTNINE
IYD---DFGN--HFIS---LHQFSGYDYFMKYL-PNNNLENLEKQLDIIEIYF-------
---PSFDQRKKGYKLNLSNRKKLPNESLVTI--LHNEVENIADSLVINNIY---------
DEYPIWSIP------VNFKGSKWCLEQ--TGNDMYRGRAGILLFMYYVKLLKDKSS-YTQ
-------LY--NKML----SAIPPSVSLSKTT--------------------FGLTGDIG
YFI------VLSI-------IEDYDTNTLACLNYIK----SVLTELEKTDFASVSNKS--
--DYINGLLPLINTLVRY----YRRGIE---KERVLRLVLSLGDTL--------------
--------YNDVSERDNSNFG----------------YSFGHGLSGVIFTLKNIYKVTRL
----K-----KYKE----LILQLVPREKI----------------------------KIH
SLKW-CSGEFGTLVN---------------------HPQ------------------SVP
EGIVASL---------DND----TFCHGSMAIINFY-IDYMK---EMDTS-----MELES
LLCSVVMNKSKEG--------EYRIVQTS-----NFPDFSLY--TGVTGIA-YTFLRYIA
LNQNDKKIV-IPSLLEI------------------------------------------
>NC_009142.1|c20|4916931-4920044|-|YP_001106583.1|lantibiotic_modifying_enzyme
-----------------------------------------------------------M
IGEDALTLGEYLDLPPGECARP------------------------EVLKRIDAATAFWH
A------------------------DAGLAEAVPTSLDGRSGPELRRLVA----------
-----------ERRIDPGHPVAEATGELDDVL------------RAWTRTAEHDAGDWES
AVHDVIAPLVEAA---REHALREV---------AGHPAVLSADTARTACREWLRSPP-PS
LLQTVVGAFVVD------------MRAAQR-----L----AGEAS--SQRNWFAHHLAAV
CADSSSRKAFFGRYPLLTRFLRVRLRNWADAAVEFALRLDRDHGALTGLL----------
----------GTDRLTVARVETGLG--DAHNGGRGVARVVFE---EG--------AVAYK
PRSLRATRVLRDLLSLLEE---------RYGVSAEV-FLPEVIDQGEYGWAEWID--PEP
CRTAE-DVADHYRRLGELQAVVWLLGATDLHSANI-VASGGRPFLVDCETLLSPVS----
------AATGRGRTRPEILRESPMSTGVLPVDATLGIGH-----VRDISAFGGGV--GGA
EWRMPDWAAA-GTGDMH-ATTRAVRLPPG----ASLPTR-DDGVEVD-----PYAHDRHF
LAGMAGTS-AA--LARIAGDLAADPSFESLVSG-TPVRVLLRPTAEYVQVIQALRHPAVL
HN---AFLAEG-AFECLL----QEPVHADPAHQRTVYAAERAALLRGDIPYFEVHAHRRD
LIG---CDGS--VIAD---FYDASPIDHFRRRV-RRLAVGGEALG-WAAEAAV-----YC
GKLNAHGRRAHSAGKVAHHHRPDGARGGESH--LVAGATALAEWIARMSYD---------
--GRSWLSV------TLDENERWKVLP--AGGSLYLGTTGILLFLDVLCRETGGSAEVLR
-------V---RDTL--------WEHWIGSYPTEL-------HEGNRGAL--IGLAGDL-
HVT----QLFGHH-------SGDPRLRA-RAEALLD----RLADEVEGL-----------
--DLLTGTAGIVLVLSRV-----AADPDNPLRHRAAATAARHVRRL--------------
---------LREERSGSDGCLWDLDGDKRST------TGFAHGTSGIAYALHEFADVAHE
LGCWA-----ELVDPCRAAFDRACEWERS--CGPAAMKWP--------------------
--TW-CNGAAGLALARA---AVLRGSG---------RAS------LVRDLED-----AVG
SCLSAEL--------GRRH----TLCHGDLGVAEAL-LQGAR---ATGRR--DWRDAAMR
IGAEAATWARNSE-------GRIAETDAG-----DVLSPGLL--GGAAGVG-YELLR---
LARPAR----IPSILTLERPA--------------------------------------
>NZ_ABFV01000004.1|c1|83484-86651|+|ZP_06561438.1|lantibiotic_modifying_enzyme
-----------------------------------------MDGRRRAAIHRTDSGGGTV
IGEDALTLGEYLDLPPGECARP------------------------EVLKRIDAATAFWH
A------------------------DAGLAEAVPTSLDGRSGPELRRLVA----------
-----------ERRIDPGHPVAEATGELDDVL------------RAWTRTAEHDAGDWES
AVHDVIAPLVEAA---REHALREV---------AGHPAVLSADTARTACREWLRSPP-PS
LLQTVVGAFVVD------------MRAAQR-----L----AGEAS--SQRNWFAHHLAAV
CADSSSRKAFFGRYPLLTRFLRVRLRNWADAAVEFALRLDRDHGALTGLL----G-----
-----------TDRLTVARVETGLG--DAHNGGRGVARVVFE---EG--------AVAYK
PRSLRATRVLRDLLSLLEE---------RYGVSAEV-FLPEVIDQGEYGWAEWID--PEP
CRTAE-DVADHYRRLGELQAVVWLLGATDLHSANI-VASGGRPFLVDCETLLSPVS----
------AATGRGRTRPEILRESPMSTGVLPVDATLGIGH-----VRDISAFGGGV--GGA
EWRMPDWAAA-GTGDMH-ATTRAVRLPPG----ASLPTR-DDGVEVD-----PYAHDRHF
LAGMAGTS-AA--LARIAGDLAADPSFESLVSG-TPVRVLLRPTAEYVQVIQALRHPAVL
HN---AFLAEG-AFECLL----QEPVHADPAHQRTVYAAERAALLRGDIPYFEVHAHRRD
LIG---CDGS--VIAD---FYDASPIDHFRRRV-RRLAVGGEALG-WAAEAAV-----YC
GKLNAHGRRAHSAGKVAHHHRPDGARGGESH--LVAGATALAEWIARMSYD---------
--GRSWLSV---TL---DENERWKVLP--AGGSLYLGTTGILLFLDVLCRETGGSAEVLR
-------V---RDTL--------WEHWIGSYPTEL-------HEGNRGAL--IGLAGDL-
HVT----QLFGHH-------SGDPRLRA-RAEALLD----RLADEVEGL-----------
--DLLTGTAGIVLVLSRV-----AADPDNPLRHRAAATAARHVRRL--------------
---------LREERSGSDGCLWDLDGDKRST------TGFAHGTSGIAYALHEFADVAHE
LGCWA-----ELVDPCRAAFDRACEWERS--CGPAAMKWP--------------------
--TW-CNGAAGLALARA---AVLRGSG---------RAS------LVRDLED-----AVG
SCLSAEL-------G-RRH----TLCHGDLGVAEAL-LQGAR---ATGRR--DWRDAAMR
IGAEAATWARNSE-------GRIAETDAG-----DVLSPGLL--GGAAGVG-YELLR---
LARPAR----IPSILTLERPA--------------------------------------
>NC_011969.1|c3|4825918-4829076|-|YP_002532646.1|lantibiotic_modifying_enzyme
--------------------------------------------------MLIHSYINEK
AFAKSLNLKERYKTLMSRRDLL------------------------LSEDLNLAQLNKWI
D--------------------KMFRSNKADFDFKLKMNEMTKEDFASLIE----------
-----KIPESKEHLYIDELNEHVNLRVLEMGI--------------ELCDSKPLSAEEDL
GFIEFVRPFALYA---AEMIDSSL----------KYRLNKICYEHEEIKEMLVRSLV-EE
LLNNAVRSLVLE--FN-------IAKLREE-----L----IGETP--EER--FLSFVREK
ARNKENLIAFYEEYATLTRRLILRTEYFIQNVQMLLFRLNENWLQLQKEF----Q-----
-----------LQDASLSEIKVGLG--DTHQEGKTVVQLVFS---SG-------KEILYK
PKSMEITKSYHAFLEWMNE----------VSGSIQL-PSYKVLDCGEYGWEEKIL--YKP
CSSKE-EVERYYSRFGKLIGLMHMLKGADLHFENI-IAHGEYPYIIDSETIFHQYP----
---KLNFPDSAEVKLKYEQSDSVIGSGLLPQAMFQNIDGK----GIDLSALNGKE--QDL
PFKVLALNQN-SKDEME-FTMKEAKSQSA----KNLPKLGVEEIYVE-------DYLNFI
IDGFQEMC-KF--FIEYKDEILSERGPLITFKE-NKIRIVARATQQYCNFLQESTHPDYM
RD---SILLEQ-LFERVW--------YYPYENKELV-IHEIQDLLRADVPIFTTFTDSRD
LYS---STGE--KMED---FFKESGYEQVYNKI-YHFDEKELEKQRGWLKLAI-------
------QGNREIDIKVRRKESYRSELLENHQETILQEAINIGESLVENVVL----S--DD
KTTASWLQA-------NVIHDKWYVAP--MKQNLYDGLGGVALFLLYLNKVTGNEK-YLE
-------VA--HKAL----KSAM--NPLSKAKGLL------------STF--LGKYSLL-
YPL----AHFQSI-------SPRKEYQD-FLEEIKV----ELKERLKEEEEF--------
--DLLSGSAGVIQVALNV----FEMTK----DQDYLDLADMYSKHL--------------
---------AENVSILENGVAWKNKHTNSYL------GGFSHGTSGIAWSLWRSGIMNRN
----Q-----EYID----LAKKALAYDRS-LFDKEESAWK-----------DTRESEKKC
LHQW-CHGSTGIGLSRV----LVRSYE---------EDV-----EMDEEIRV-----AVD
NVRKYGF-------K-NND----TLCHGNMGDTELL-LAVSQ---LYGNK--ELYEQAIQ
IGIQVINNYRETG--------SYQCDAPD-----DIQSFGMF--VGIAGVG-MQLLR---
LLQPNE----IPSVMTLENVKG-------------------------------------
>NZ_ACNI01000070.1|c1|99525-102308|-|ZP_04085249.1|Lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MYKRTVEKHIKEYET
TFGDFYRPILLNLEDTIEDLLNTY--------------SEQINEKEIILNDIIKSLL-YE
LNRISFRTLLYE--FH-------LTKESTE-----------TNTQ--DHH--FKNYIQL-
LKDSNYITMILDKYEHLNKLINKKINFKIQLIKNIFESFSNDKSKLQQHI----D-----
-----------NQIHTIHGIEFSHG--DSHNQGKSVTILQTN---SG--------KLVYK
PHNLYTDQWFCDILNVLKE-----------DINIDI-PEIPLFTVDDYGWQGFIS--HKP
CTNKE-EISNYYYRMGIYLSVFYLLKTDDIHYENI-MASGEYPFILDLETIVANKK----
-IHSDEEKESLMYTFLESITDSVLGTMILPVNYKFSPF------DVDISALSTKEA-ESN
IWLSYVIEDA-GTDNIR-LIKQPSPLNKK----NNKV-M-LHNKVAN-----PFDFLNSI
ENGFSHGY-DS--ILKNKHKIT--EICHSNLVNKIHVRHIPRATSVYAKFLDASTHPTYL
RK---TETVNM-LFNKFK-------RGTSFTEIKQA-ESEILALFNHDIPYFTQPLISKN
LHC---NEVS--VIKD---YFQDRPIDLVLNRL-KNMDKKDKEKQVYYIKMSM-------
------VTDGGGSLANIHGNQVLGFQNTEID----SILKEVGNELIDTAII--------Y
KDTCTWMIH---EV---TDNEKVYIGP--LNYSLYDG-AGLLIFLLELASYSDNKK-YLQ
-------YA--EMGL----------KGLVTDVDLS-------KIDSYSIF--HGLGSYL-
YLY----ARFYNT-------TQKSEYYNKLLDGVKN----LNITYKKDLNI---------
--DFIGGLSGMIVFLTNC----YRAYG----DEIFYKKAHEFAELM--------------
---------ISIYKEKTEFL-----------------NGLAHGRAGISLSLASLYEINND
----A-----KIST----EVYKVLKQENL-HFNSTDNNWT-----------DLREFINTE
SVYW-CHGAPGISLARM---KTIQYLG---------INN-----LLNKDLTC-----GIR
KTLQDGF------SDYHDS----SLCHGVFGNLDIL-IEINK---YKKCE--TLRHFIDS
TFSNYIDNLTKFG---------YQSGIKN-----SLPINNFM--LGKFGIA-YTLLR---
YKNNK-----IPCILSLDI----------------------------------------
>NC_008024.1|c3|1678734-1681568|-|YP_603221.1|serine/threoninedehydratase_/_Lanthionine
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MIKRNELKLEYQQHQFYEYFNSIF----------------------------
-DYDILDTSISENIYLLREKTHKL-----------------------FYSEFENQLF-ET
IMFLSMKTLVLD--IN-------HFSKEIE-----------------NKSKAYEQYIQQ-
IREENGISNFFDRYPYLLKQINREVGLVVESYSLLFDRFLKDLSEIRSCF----------
-----------NITESLSNVEFSLG--DSHSQKQTVVKIEF----KG-------KSVYYK
PKSYDSYNILLELISLLKS-----------NNIPSF-SLPESLIKADYCWQLGVA--YTS
SNKDE--VAKIYFKYGVLAAFSEIFSITDLHMENV-IVSGGDLYLIDVETFFQRKL----
-NVQNQNFEGITVDTYQRIYKTSLSNGLFPVQFEKNS-------APNVSGISGKG--GKR
KKGKYELINK-NRGDMK-LVKTDYFQEDG----YNI--LTLNGKVVE-----PLDYANEV
IAGFRECY-TF--LMSQRAKVK---KILEDFPK-LKTRAIFRNTSDYGKFLQASTNPKYL
FS---EKKREN-LFSILH--------ESKHIEQFIV-VSEIKDLMNGDIPYFSMDTSG-N
VYN---SLGT--VIGN------LGETTSLFDNI-VTLNDERMKFTCELLGIVL-------
--KKPIKHWEREKGKSYQFLSISSEHNFSEE--ILDSIRRIFIDADKNSFS--------S
EEEITWLNI------DITETEQWVISP--QNITLYNGLIGNALGYLYAYQILGEEQ-YLV
-------SL--NKIL----------KTLETTKNLI-------ETSDMSVF--LGKGGLI-
YLY----FSLWKR-------LKLPQYQKLYLDIIKE----FSSQSLEEQNI---------
--DYISGVSGLLVVLCNI----YNVEQ----NKTVYHLINRISEFI--------------
---------IDNVKKEDDKVYWVSDFSDSEIL-----NGLSHGQSGIAYALLLSWKINKN
----Y-----NYFK----IAKSAIDFENT---RISDGNWI-----DFRNKGKRSELGMPE
PIYW-CHGATGIGLTRY---RESKWLN---------DKE------LKNNYEM-----AKQ
TVLNNGY--------LNSD----CLCHGKMGNMELF-MNLDD---SLKNE-----VDIEG
IILNIVRNSQKFG---------WESGLPQ-----HTRVFNMM--VGEIGIA-YQLLR---
YISNYE----VPSLLLLDVPKGSIENEKDYTD---------------------------
>NC_004070.1|c2|1661849-1664683|-|NP_665455.1|putative_salivaricin_A_modification_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MIKRDELKLEYQNHQFYEYVNSIF----------------------------
-DYDILDTSIRETSEVLRKKTHKL-----------------------FYSEFENQLF-ET
IMFLSMKTLVLD--IN-------HFSKEIE-----------------NKSEAYEQYIQQ-
IREENGINHFFDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIRSCF----------
-----------NISEPLSNVAFSLG--DSHSKKQTVVKIAF----KE-------KSVYYK
PKSYHSHSILLELTSLLKS-----------SNIPSF-SLPKSLVKADYCWQLGVA--YTS
SNKDE--VAKIYFKYGVLAAFSEIFSITDLHMENV-IVSGGDLYLIDVETFFQRKL----
-NVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNS-------APNVSGISGKG--GKR
KKGKYELINK-NRGDMK-LVKVDYFQEDG----FNIPT--LNGKVVE-----PLDYANEI
ISGFRECY-IF--LLSQRSKIK---EIVEGFPE-LKSRALFRNTSDYGKFLQASTNPKYL
FS---EKKRKN-LFSILY--------ETKHIERFIV-DNEIKDLMNGDIPYFSMDTRG-N
VYN---SVGT--LIGN------LGDTTSLFDSI-TILNDERLKFTCELLEIVL-------
--KKPIKYWEREKGKSYQFLSISSEHNFSEE--ILDSIRRIFIDADKNSFS--------S
EEEITWLNI------DITETEQWVISP--QNITLYNGLIGNALGYLYAYQILGEEQ-YLV
-------SL--NKIL----------KTLETTKNLI-------ETSDMSVF--LGKGGLI-
YLY----FSLWKR-------LKLPQYQKLYLDIIKE----FSSQSLEEQNI---------
--DYISGVSGLLVVLCNI----YNVEQ----NKTVYHLINRISEFI--------------
---------IDNVKKEDDKVYWVSDFSDSEIL-----NGLSHGQSGIAYALLLSWKINKN
----Y-----NYFK----IAKSAIDFENT---RISDGNWI-----DFRNKGKRSELGMPE
PIYW-CHGATGIGLTRY---RESKWLN---------DKE------LKNNYEM-----AKQ
TVLNNGY--------LNSD----CLCHGKMGNMELF-MNLDD---SLKNE-----VDIEG
IILNIVRNSQKFG---------WESGLPQ-----HTRVFNMM--VGEIGIA-YQLLR---
YISNYE----VPSLLLLDVPKGSIENEKDYTD---------------------------
>AY005472.1|c1|2722-3657|+|AAG32537.1|SalC
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MSVFLGK-
------------------------------------------------------------
----------------------------------------------G--------GLIY-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------LYFSLW--------------KRLK-LTQYQKLYLDIIKEFSSQSLEEQ
NID------------Y---ISGVSGLLVVLCNI---------------------------
-----------------------YNVEQNKT--VYHLINRVSEFIIDNVKK--------E
DDKVYWVSD------------------------------------------------FSD
-----------SEVL---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------NGLSHGQSGIAYALLLSWEINKN
----L-----NYFK----IAKSAIDFENT---RISDGNWI-----DFRNKGKRSELGMPD
PIYW-CHGATGIGLTRY---RESKWLN---------DKE------LKNNYEM-----AKQ
TVLNNGY--------LNSD----CLCHGKMGNMELF-MNLDD---SLKNE-----VDIEG
IMLNIVRNSQKFG---------WESGLPQ-----HTRVFNMM--VGEIGIA-YQLLR---
YISNYE----VPSLLLLDVPKGSVESEKNYTD---------------------------
>DQ889451.1|c1|671-3505|+|ABI63629.1|SalM
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MIKRDELKSEYQQHQFYEYFNSIF----------------------------
-NYDILDTSISENIYLLRKTTHKL-----------------------FYSEFENQLF-ET
VMFLSMKTLVLD--IN-------NFSKEIG-----------------NKSEAYEQYIQQ-
IKEENGINNFFDRYPYLLKQINREVRLIEESYSLLFDRFLKDLSELRSCF----------
-----------NITEPLSNVEFSLG--DSHSQKQTVVKIEF----KG-------KSIYYK
PKSYDSYNILLELISLLKS-----------NNIPSF-SLPESLIKADYCWQLGVD--YIN
SNNDE--VKRIYLKYGVLAAFSEIFSITDLHMENV-IVSGGDLYLIDVETFFQRKL----
-NVQTNNFEGITVDTYQRIYETSLSNGLFPVQFEKNS-------APNISGISGKG--GKR
KKGKYELINK-NRGDMK-LVKTDYFQEDS----YNIPT--LNEKMVE-----PLDYANEV
IAGFRECY-AF--LMSQRAKVK---KILEGFPK-LKTRAIFRNTSDYGKFLQASTNPKYL
FS---EKKREN-LFSILY--------ESKHIEQFIV-DNEIKDLMNGDIPYFSVDTSG-N
VYN---SLGT--VIGN------LGETTSLFDNI-ATLNDERMKFTCELIGIVL-------
--KKPIKHWERKEGKSYYFPLISSKQSFNEE--ILDSVRQIFIDANKNSFS--------S
EEEMTWLNI------DITETEQWVISP--QNITLYNGLIGNALCYLYAYQILGEEQ-YLV
-------SL--NKIL----------KTLETTKNLI-------ETSDMSVF--LGKGGLI-
YLY----FSLWRR-------LKLPRYQKLYLDIIKE----FSSQSLEEQNI---------
--DYISGVSGLLVVLCNI----YNVEQ----NKTVYHLINRISEFI--------------
---------IDNVKKEDGKVYWVSDFSDSEIL-----NGLSHGQSGIAYALLLSWKINKN
----Y-----NYFK----IAKSAIDFENT---RISDGNWI-----DFRNKGKRSELGMPE
PIYW-CHGATGIGLTRY---RESKWLN---------DKK------LKNNYEM-----AKQ
TVLNNGY--------LNSD----CLCHGKMGNMELF-MNLDD---SLKSE-----VDIEG
IMLNIVRNSQKFG---------WESGLPQ-----HTRVFNMM--VGEIGIA-YQLLR---
YISNYE----VPSLLLLDVPKGSIENEKDYTD---------------------------
>AY005472.1|c1|820-2466|+|AAG32536.1|SalB
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MIKRDELKLDYQRHQFYEYFNSIF----------------------------
-NYDILDASISENIYLLRKTTDKL-----------------------FYIEFENQLF-ET
VMFLSMKTLVLD--IN-------SFSKEIG-----------------NKSEAYEQYIQQ-
IKEENGINNFFDRYPYLLKQINREVRLIEESYSLLFDRFLKDLSELRSCF----N-----
------------ITEPLSNVEFSLG--DSHSQKQTVVKIEF----KG-------KSIYYK
PKSYDSYNILLELISLLKS-----------NNIPSF-SLPESLIKADYCWQLGVD--YIN
SNNDE--VKRIYFKYGVLAAFSEIFSITDLHMENV-IVSGGDLYLIDVETFFQRKL----
-NVQTNNFEGITVDTYQRIYETSLSNGLFPVQFEKNS-------APNISGISGKG--GKR
KKGKYELINK-NRGDMK-LVKTDYFQEDS----YNIP-T-LNEKMVE-----PLDYANEV
IAGFRECY-TF--LMTQRAKVK---KILYGFPK-LRTRAIFRNTSDYGKFLQASTNPKYL
FS---EKKREN-LFSILY--------ESKHIEQFIV-DSEIKDLMNGDIPYFSMDPNGNV
YNS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------LGTVIGNLGKTTSLFDNIATLND
----E-----RMKF----------------------------------------------
-----TCELIGIVLKKP----------------------------------------IKH
WERKDGK-----------------------------------------------------
----------------------------------SYYFPSI---SSKQSFN-EEILR---
----QR-----------------------------------------------------
>NZ_ACNI01000070.1|c1|102859-105849|-|ZP_04085252.1|Lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
---------------------------MQLYPELQSKEELEDLIYRVSST----------
--------TIDELYKQSKNDSENKFKFKSHKL--------------NTEDVIDIGISSDL
PFGSFCKSIVIDP---LNLFFKDL------------KKIKIINDYTYFTTNVADQLI-SR
IWELSYKTLIDE--LK-------TLKNEQL-----L----IGKTE--EAR--FAYFHDVL
LKNDEYIEYLLEDNQQLSSTLRIIINRTLKNILAILHRTQAEWNNLLNQF----H-----
----------INNDAKLTLIDVGMG--DTHQDGKTVCTLHFS---DD-------SRIMYK
PRNLEVDQAFQDFLKFLNT-----------KRITEF-NTVNFFSSSSDGWMEFIS--QKE
CTEEK-QINEFYKKTGQYLAILYILNANDIHYENI-IAHRENPILIDLESLFVPKP----
-NHYFEEFDSSFQKAQEFLHTSVNSIALLPTEITRSIDGTDL--YADLGGVSFNKK-QIS
PYKSVILNNK-NLESMD-FSLRNLELEPK----HNNP-V-LNGTTLE-----AYDYIQDI
QDGFKSMY-EW--AIENKEELV--SKIQQLFTG-KRIRFINKSTMFYSKLLDMSTYPIFS
KN---SFYKKL-LFHRVG--------LDGFKSGHPFLKHEYNDLLNMDVPYFSAITNTKN
IYN---SNGD--DIGD---ILNDTPLERCLTKI-NNLSLTDLSKQLKLIETSF-------
--LNKRKGHEDCTKISFVQEKSNHPKYTINYHSYLKSAKNIGDHLINEMIT--------A
DENGYWIAP---SLEG-EQENIWSPGL--VSLDLYSGNAGISIFLAQLYSCTGEMK-YKD
-------AA--YKAI----EPIR--KFITELEENS------QLPFPLGVF--SGTSGYL-
YAL----YKTGIL-------LGNTELEN-LFFDNID----KLKSFVIKDKTF--------
--DVIGGVTGTIHMLLNI----AANCHVTKNKNHLIRLSIELEKHL--------------
--------HQHPVFKDQGKIY----------------AGFSHGIAGIMSCYALLYKNTKK
----P-----IYKN----IAVELRDKLNN-FYSPVQQNWY------------NSNQNNDI
SNGW-CHGAPGILLSFL---ICMECGI---------EID-------DTYVRI-----AIN
STKDKAL-------G-NNI----TYCHGDLGTLSIL-ERCAN---QLNDS--VLSSQVEL
TFECLHQQYLKEI---------VSKNTIR-----HSYSFSLM--IGITGAG-LALIN---
KVNKI-----KTNILWIN-----------------------------------------
>NZ_DS999412.1|c2|3456169-3459069|-|ZP_05136619.1|Lanthionine_synthetase_C-like_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MTASPAAA
VFARITEHFLADA---RAALAAGL----------HDPAIDLQPDERKLLHGQGDAALREH
AQLKLNRVLLLE--LH-------AAARGGD----------IGPL---ESAGALDEFMAL-
ATSEGFQEHLQRRYPVLLPRLSRMLDGQCAAVVELAARIGSDRALLTELL----D-----
-----------RPAGAMRAVSLGRG--DLHGGGRTVARLQF----DG-------GTLMYK
PRSLRIDATLDGLLAAVFG-----------EGADRV-RVPRVVDRGSHGWAAFAA--HRY
CSGDE-ELRAYYRGLGHWLAILRLVGGTDIHLENL-IAVGPVPVVVDAESVFSRVI----
-DVEPSGLGDAYDTAVKLMRNSVLRTGIVPFRTTGLGME-----GVDLSAAGALPG-EQP
RVQVPVIIED-GTAPAR-LGLVEAEVAIA----QNHP-----SPQPD-----VSLYWDHI
SEGFVDAS-GRLRALDAKGELM---PLLAGFEG-CQVRDVRRPTMAYAELGRMLWHPASL
HNEAQAVERAVDLLVRNA-----AVSPAAPSDLDTV-RGEVDDLRYGDIPIFASLLDAPR
IHS---------IVAN----WRA-----------MRIDLEDVTIRSTLVATDL-------
----NQHALARAEARSGYSYAARQPRADGLDARRRALAARAVENLLRLAVH-------GE
DGSMTWITP-------EVTRSGWTVQP--VQPDLYFGLGGIAFALAAYRREAEQGR-ADP
-------VAGLEPAI----EGAI--AVFQTMCERH-------PAEIDGGF--VGTGSQI-
WTL----LALHDL-------LQRPALLALAEHCAEA----AERRGFQGPVKF--------
--ELIDGVSGMILPLLAL----AEATG----SARWLDLAAAAGRRM--------------
---------QDAAIVDADGARWPTPQFREPI------GGFGHGAMGMGWALARLARSSAG
----SATERAAWRQ----LAEEAFAFQAA-LFEPHTGHWR----------DIHLQDGQKN
FPTW-CHGSVGIGLAAA---DLYARTG---------DPA-----QLRDMRRA-----VAD
ARGKWGF----------SH----TLCHGDVSTRELL-VLAAA----LDPE--GCPYARDD
AAIEIVSSIEEHQ--------GMVGGLTR-----AAFTPGLM--IGLAGAI-YGFLR---
MHPACV----LPSPLLQETASARAGVTEPRFSSEQAAPAALAEA---------------
>NC_013131.1|c13|5051460-5054339|-|YP_003115146.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MTSRFSGEFAG
ALGCLAAPVSAGLAARLAAVEDLS-----------------DPERAAIAEAAERAIL-ET
VHRKVSRVLLLE--LN-------AARLSGR-----L----TAEDS--AGR--WDEFVNL-
ADSLTFWHSLSSRYPTLQQRLDTVMQRRADAAATLAERFAVDRRALRTLT----A-----
-----------IDPGELRHVTFGAG--DSHRGGQSVAILELA---EA--------TVVYK
PRPVEVDKALTHLLQTVLP---------DVPVATRI-RVPEVVVRDGYGWSEFIP--HRY
CASDA-ELTTFYRGVGHWLAVMRLLGGSDLHTENV-IAAGPVPIVVDCETLFSTIP----
-AGPPSGMGQAVDTASKLVDETVLRVGMLPNRGAALGWR-----GVDSSSVGALPD-EQP
SGQVPVILDA-GTDRAR-LGFAQATPQPA----ASLP-----SPKPN-----LADHWETV
AAGFEEGSAAL--AAADAAGIL--EPAMSVFSD-CQIRMVLRATDVYEEVARMLWHPVSL
HGEPAAVERATELFVQMA-----RQSPAAPGDPDVV-AAEIADLLTGDIPYFGTTPRSGR
LTG---PGGT----------HWLPEQDLVADAL-TRWRGADLEFDRGIIRATL-------
--VSAYLNADWTPSKGLRAPTDVSTQDFDKR--RRTLAAELVREVRDTATR-------GS
DGTATWIAP-------VLSLTGWVVQP--LSPDLYSGLPGVALLLAAYERESDAGR-ADR
-------LDDLPALL---DATIQTIRLAGDHAAKLRADGVAMRPREPGGW--VGLGSEL-
WTW----LTLRRL------GVVGDEALE-RSRTLAA----LIPEAIGDADEY--------
--EVCAGPAGAIVPLLQL----SAATG----EQRWTDIATHVGTVL--------------
---------CDAAIAKDVGMTWPTLRWPGGL------GGCAHGASGIGWALARLALATGD
----A-----RAAE----TARAAFAFEES-CYVPEVGGWS----------DLREIEPGLT
ANAW-CHGSVGIALTQL---DLLRRGW---------PAD-----GVEDLLRR-----AAN
AALGHGM-------G-WNH----TLCHGELGVWELMDAALRD---GFAPP----SVDREG
FEARIVASLEQNG---------AISGMAR-----DAFSPAMM--SGLGGVA-YQLLR---
MGAGSA----LPSVLVLDDPL--------------------------------------
>NC_009937.1|c3|3671088-3674003|-|YP_001526124.1|putative_lantibiotic_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MTPPLALTSGGSHRSGRQNGHRSVS--------------GSRHAEPTRTVLPM
PFSDILAPLAVAR---ATRLEAAL----SAAGAPLS---------AGARRGAIEALL-ER
LNAVAMPVLAEA--FTGDTPPPAVARLFDD-----P----PDFVP--RER--YAAFRAEL
MGADG--LPCLDRWPVLRDRLTKICADWEYNIAAFAAHLAQDADALRWLV----P-----
--------AWRERIPDIADLKGGLS--DPHAGGRSVWRVDFA---DG-------TRLAYK
PRSLAAECAFSRLLAELAG-----------DETVPAQRIPRVLDAGDHGWMEWIE--QAP
LADAD-DARSYMERCGGLLALVDLLRGGDIHPDNL-VPAGAFPVIVDLECLFQPAP----
---------ADLGQPDPLEDPHLFSNGILPVFTSFDG-------GARMVAIAAAGA-GPV
PLRPETVVRHPGTDWLF-LGNRQVPSF------ADGP-T-LEGRALD-----IRDHAADL
ARGYAATL-RG--LIRRREALLAPGGALDAFRK-VPCRLLCAATNIYALVLA----PALL
GE---GATSEAVFTAHLARAAGREPLMADASHWGHVLEAEAAALSRLDIPAFLFRPDGRE
AWS---VEGR--PLGP---VFAAPMFARVEARL-WALDEAAVADRARLIAAAV-------
----------------TPAPSA-RVVTGPAD--VAALLRHCADQVAALAVP-------QE
TDAVVWARL--------WEQIPALIAP--AGPGLYYGSSGIAVFLAEAGRVLDDPR-LLD
-------LA--RRAL----RPTS--ARVRAGAAGA-----IATGCGAGYA--QGLGGLI-
AAL----CWCADL-------LDDPGLMD-DAVALAR----ETPQALAASTGVP-------
--DLMQGAAGLALGLGLL----HQSA-----GDL-SPFLTACGHAI--------------
--------LEGSGLEANGTRHWPDGPQPGL-------PGLSHGTAGMAAALAHIHRVTGD
----A-----AYRD----AALEALAYEDT-MFNAEAGTWT---------GEGRASRLHHR
MSSW-CHGAPGIALARA---MVMATLG--------PAAA-----PLAPTLET-----ALE
LTRATPV-------P-AAD----DLCCGEAGRLEIL-SVLSA---RLGRS--DLMADVDQ
ALAQRLPDWARGE------ARLLAAAAPR-----APGDAALF--RGWAGVG-HLMVR---
RLAPHI----ARDVLLPWAV---------------------------------------
>GQ900454.2|c1|2548-5658|+|ADA80185.1|lantibiotic_mersacidin_modifying_enzyme
--------------------------------------------------------MENN
TFYKTLTLEERKELSDIT----------------------------KHIPPIKQAYPYWR
K--------------------LLEVEKQEFNDILEKYSNIHSDDLDKLYE----------
---------VENTNNKIFNSNKTSYNNIKKLY----------YNADYSINKDVLEKLELK
LFYPILIPIINLF---IDKFKKYQ---------------FNYMINKNCYLELINQIA-EE
TLQIFIKTLILE--LN-------LEKKAGK-----L----EGNTS--EEG--YNEFCKK-
LYEQKYLCELIDEYPVLFKLISDKIEGFTKLTTTILSSFKQDISELKKNM----L-----
--------ISSDFNGKINNLTASLG--DTHNGGFSVSIIELD---NS-------DKIVFK
PRDLNIDTKFNDFLSWINN---------QIDSDIYL-KGAITINKGSYGWVEFIE--HQT
VNDSN-QLHEFYNNLGAMLAVLYVLNATDFHYENL-IAYQQYPVLIDLESLVHHSI----
GESDRLTESNSVNKAAEFLKYSVLSIGILPHRKISVNNQ-----NFDISGINNTED-QVI
PFKSEKIENH-YTDNIK-ISKFYGKMRQA----SNAPYK--NTEEFK-----IESFMYDI
TDGFKEVY-TI--FLNNKNIVK---KELDKFKN-VKVRKILRDTMNYSRLLNLSLHPDFL
RN---QIDREL-LFLRLE--------KQEESNKTIL-KNEVQQMIVGDIPTFYSYTDKQD
IYT---YKEK--LENG---VFDVSGLDIINKKI-DNLSFNDLKNQTHLIESMI-------
---------LEFLPKQNKKLNSIFKNIDERN--VLEQVEKVANLILSSSLQ---HE--YS
DKELIWIGL---NMYG-INEEDWKFSV--SDLSLYDGNTGISLFFAYLWKVTNNEK-YKI
-------AA--YKAI----KPIL--LIMEDLFKSE--------KLTIGAF--EGISGPI-
YAL----HHLGKV-------FQDENLID-KCLYFTK----QLDKYIDSDRIF--------
--DIVGGSSGALMVILNL----YEDFK----EKWIFTIAERLSNHI--------------
---------INNSIKTKKGIHWPRIGESSNPY-----IGFSHGVTGVLTSLSLYYYYKPQ
----K-----NILD----LIKSGIQFEDS-FFSDKKYNWY-------------SDHLSSY
PIAW-CHGSPGILLGRK---LISENLK---------YPN-----IIQDSFLK-----SYN
SIIHREN--------NSNY----SLCHGELGLLDIL-CNLRD---FFEVD----------
---YEINNIKENL---------FLSDIKE-----QYKNYGLM--TGLSGLG-YGLLR---
MYFPNM----IPSVISLERPNLYKESK--------------------------------
>NZ_ACOK01000098.1|c1|5724-8798|-|ZP_06143781.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
--------------------MDQQNTQIARYMLSLYPEFEDYETLSRYLE----------
----EKCRITGDHFLSEFRSESEYTPEYTEES-----------RCDVFSEVKEILTSKNA
MFAGYFAGFLVKK---YKALSDAA------------EASEICSDPSAITADLVTQIY-SS
LSNIAMRTLIFE--LE-------SAKKHDL-----L----KGDTP--DER--FRYFRDTL
LEDEKYVERLHSEYRIMHSQLTETAGNAMDFAIEMLNNTASHINAIRQEI----F-----
---------GGRDMGKLVHISMSGG--DTHVRCRNVSTMIFE---NG--------RLVYK
PHSLKSEAAFQVLLGKLNE---------HLDEESRI-RLTKIVTEEDYGWTEFIE--HTP
VSNDG-DAKVFFRKSGILLALLYICNATDFHFENV-IASGTDPIPIDLETLFHCQP---A
DKDHDKDREGGYMNTLRFFGRSVHSIGLLPSYINFRGSDGKVK-PLSVGGMSGSAA-QRS
PFSTYRLENL-GSDEVS-MVRSEYDIGSS----NNSA-V-LDDVELD-----PRNYSGYI
TDGFTDAY-RI--ALAHRDELK--ELVLKLFAD-TRNRIVLKATFAYSNLLNISTHPDFQ
RS---EIFAKL-LFSRMG---------LVKPAEDFI-DYEIDSLLHRNVPIYYADFTKRR
LIS---GDGR--IFNN---VFEQSPQEEFIDKI-DSLSEHDLEMQTDLIKTSY-------
-----FIRNMAADHTAVDLHKIPVFRAKDED--LLRTASEIGDYLIDHRSIGGVNH--KG
KRDRFLIGC---EIER-TDHEDWTTVM--SDFNFYNGASGAALFLRYLGRATGEKK-YTD
-------AA--YELI----EPII--SVMEAGNFNY--------EKNVGAH--TGIAGYF-
YVL----NKFAEL-------DDDDGLRQLMKDSLSK----ITELAAEETKCFF-------
--DLISGVSGALAVTTGL----TADSSDSELRELAMKTSGELLDIL--------------
---------RSRTLRDGELIAENIEY-----------SGFAHGIAGAIPYIYRYYRQSGS
----E-----EALD----LFRKLLTYERTRFRQTENGTIK---------GWLSAEHEGSI
TASW-CHGTPGFLSARL---ILRQEGY---------TDD-----ETEAEIAA-----AVE
LMKRDSI-------G-TTL----TSCHGDLGNLAIL-RKYAD---MYGDN--KLYRQCTS
TFAELYNKYASKA---------KDSSEMT-----CQKYNGIM--LGLSGIG-YSCLR---
ETDDS-----IPDHLWLT-----------------------------------------
>NC_006270.3|c4|3946283-3949363|-|YP_081203.2|lantibiotic_modifying_enzyme
----------------------------------------------------MSMKEFEI
YLYKALYSNERGG-----------------------------------------------
---------------------QGQEHPSGFFPENGKTPSRPTDFHLSSVQ----------
--------HSPNEPVQLQGKMPEWAACLSEIM-----------KYNPKAVSELKHPLPHM
SFVTFFVPFLLFA---QERMSKAF-----SEFEKQEGGLSGIIDAAGYQDGIMSELH-QC
LDKLATRTLITE--LN-------VAREDGR-----L----KGASP--EER--YVYFVEQY
ISDPEIYREFFELYPVLGRLMAEKVLRVLEIHEEIIGRFLSDRSLIAKKF----N-----
-----------IASPELVGFEGDLG--DSHKNGQSVKVLVLN---NG--------KLVYK
PRSLSIDEHYRELLNWLNG----------RGMKYSL-RAAEVLDRGNYGWQEFVK--HEG
CSSEE-ELERFYFRQGGHLAILYGLRSVDFHNENI-IASGEHPILIDLETLFDNHV----
---SIFAQNQNLHVTALELKHSVLSSMMLPVKFKHDEVL-----DFDLSGIGGKGGQQSK
KAKGYAVLNY-GEDRMS-LKETSLTTEEK----LNAP-K-LNGRPVS-----AVFYTDFI
VEGFKNAY-AI--MMKHKEELAGPSGFLNLFKH-DEVRHVFRPTHVYGKFLEASTHPDYL
TA---GDKREQ-LFDYMW------MLAKQSEKANVFIPDEIVDLLLHDIPYFTFYAGGTS
LLN---SRGE--ESEG---FYETSSIDLAKKKI-QSFSEKDLNHQLRYISLSM-------
-------ATLIENVWDHAESGL-GQKETVAD--LGKEVKHIADDLLQKAIY----S--ER
GEGPFWISN---NA---GDEKMVFLSP--LPMGLYDGMAGLAIFFAQAGKVLNEQV-YTD
-------TA--RSMI----EEIQKEESYWVQNGNS-----------HSAF--FGTGSFI-
YLY----SYLGSL-------WEDDSLLE-RALNLIP----RVLDQPNQTQNP--------
--DFIAGDSGLLTVLVNL----YEIKQHPAVLDSIRQVLSRLNDRI--------------
--------GRLLDSIEQDAVSL---------------TGFSHGLTGIAFSIAKAAKVIHD
----D-----SCKE----LVLKLVEEEDR-YFQKDHLNWL---------DLRNDS-HTLS
PSYW-CHGAPGILLGRA---HIQAFIP---------ELT-----TRTLKLQE-----ALQ
SSLNLAD-------C-QNH----SLCHGLIGNLNIL-LDIKR----------LNRELHVP
DDIFCIYKTKNRG---------WKTGLHS-----DVESLGMF--VGTAGIA-YGLLR---
LLDES-----VPSVLTLDIPTGR------------------------------------
>NC_006322.1|c2|3946135-3949245|-|YP_093632.1|hypothetical_protein
------------------------------------------MVFFAKGMTRMSMKEFEI
YLYKALYSNERGG-----------------------------------------------
---------------------QGQEHPSGFFPENGKTPSRPTDFHLSSVQ----------
--------HSPNEPVQLQGKMPEWAACLSEIM-----------KYNPKAVSELKHPLPHM
SFVTFFVPFLLFA---QERMSKAF-----SEFEKQEGGLSGIIDAAGYQDGIMSELH-QC
LDKLATRTLITE--LN-------VAREDGR-----L----KGASP--EER--YVYFVEQY
ISDPEIYREFFELYPVLGRLMAEKVLRVLEIHEEIIGRFLSDRSLIAKKF----N-----
-----------IASPELVGFEGDLG--DSHKNGQSVKVLVLN---NG--------KLVYK
PRSLSIDEHYRELLNWLNG----------RGMKYSL-RAAEVLDRGNYGWQEFVK--HEG
CSSEE-ELERFYFRQGGHLAILYGLRSVDFHNENI-IASGEHPILIDLETLFDNHV----
---SIFAQNQNLHVTALELKHSVLSSMMLPVKFKHDEVL-----DFDLSGIGGKGGQQSK
KAKGYAVLNY-GEDRMS-LKETSLTTEEK----LNAP-K-LNGRPVS-----AVFYTDFI
VEGFKNAY-AI--MMKHKEELAGPSGFLNLFKH-DEVRHVFRPTHVYGKFLEASTHPDYL
TA---GDKREQ-LFDYMW------MLAKQSEKANVFIPDEIVDLLLHDIPYFTFYAGGTS
LLN---SRGE--ESEG---FYETSSIDLAKKKI-QSFSEKDLNHQLRYISLSM-------
-------ATLIENVWDHAESGL-GQKETVAD--LGKEVKHIADDLLQKAIY----S--ER
GEGPFWISN---NA---GDEKMVFLSP--LPMGLYDGMAGLAIFFAQAGKVLNEQV-YTD
-------TA--RSMI----EEIQKEESYWVQNGNS-----------HSAF--FGTGSFI-
YLY----SYLGSL-------WEDDSLLE-RALNLIP----RVLDQPNQTQNP--------
--DFIAGDSGLLTVLVNL----YEIKQHPAVLDSIRQVLSRLNDRI--------------
--------GRLLDSIEQDAVSL---------------TGFSHGLTGIAFSIAKAAKVIHD
----D-----SCKE----LVLKLVEEEDR-YFQKDHLNWL---------DLRNDS-HTLS
PSYW-CHGAPGILLGRA---HIQAFIP---------ELT-----TRTLKLQE-----ALQ
SSLNLAD-------C-QNH----SLCHGLIGNLNIL-LDIKR----------LNRELHVP
DDIFCIYKTKNRG---------WKTGLHS-----DVESLGMF--VGTAGIA-YGLLR---
LLDES-----VPSVLTLDIPTGR------------------------------------
>NC_002570.2|c1|479086-482058|-|NP_241318.1|lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MKTPLT----------
------SEHPSVPTTLPHTNDTDWLEQLHDIL-----------SIPVTEEIQKYFHAEND
LFSFFYTPFLQFT---YQSMSDYF---------MTFKTDMALIERQSLLQSTLTAVH-HR
LFHLTHRTLISE--MH-------IDKLTVG-----L----NGSTP--HER--YMDFNHK-
FNKTSKSKNLFNIYPILGKLVVNETLRTINFVKKIIQHYMKDYLLLSDFF----K-----
-----------EKDLRLTNLQLGVG--DTHVNGQCVTILTFA---SG-------QKVVYK
PRSLSIDKQFGEFIEWVNS----------KGFQPSL-RIPIAIDRQTYGWYEFIP--HQE
ATSED-EIERYYSRIGGYLAIAYLFGATDLHLDNL-IACGEHPMLIDLETLFTNDL----
---DCYDSAFPFPALARELTQSVFGTLMLPITIASGKLL-----DIDLSAVGGGKGVQSE
KIKTWVIVNQ-KTDEMK-LVEQPYVTESS----QNKP-T-VNGKEAN-----IGNYIPHV
TDGFRKMY-RL--FLNEIDELMDHNGPIFAFES-CQIRHVFRATHVYAKFLEASTHPDYL
QE---PTRRNK-LFESFW-----NITSLMAPFKKIV-PHEIAELENHDIPYFVLTCGGTI
VKD---GYGR--DIAD---LFQSSCIERVTHRL-QQLGSEDEARQIRYIKSSL-------
-----ATLTNGDWTPSHEKTPMSPASADREDGYFLREAQAIGDDILAQLIW----E--DD
RHAAYLIGV---SV---GMNEAVTVSP--LTPGIYDGTLGIVLFFDQLAQQTGETH-YRH
-------AA--DALL---------EGMFKQLKPEL---------MPSSAY--FGLGSLF-
YGL----MVLGLQ-------RSDSHIIQ-KAYEYLK----HLEECVQHEETP--------
--DFVSGLSGVLYMLTKI----YQLTN----EPRVFEVAKTTASRL--------------
--------SVLLDSKQPDTVL----------------TGLSHGAAGFALALLTYGTAAND
----E-----QLLK----QGHSYLVYERN-RFNKQENNWV------------DLRKGNAY
QTFW-CHGAPGIGISRL---LLAQFY----------DDE-----LLHEELNA-----ALN
KTISDGF-------G-HNH----SLCHGDFGNLDLL-LLYAQ---YTNNP--EPKELARK
LAISSIDQAHTYG---------WKLGLNH-----SDQLQGMM--LGVTGIG-YQLLR---
HINPT-----VPSILALELPSSTLTEKELRIHDR-------------------------
>NZ_ACMW01000264.1|c1|5631-8813|-|ZP_04160620.1|Lantibiotic_mersacidin_modifying_enzyme
----------------------------------------MDIFYLENILYKYIKGECCM
TLQHGTYLLEREN---------------------------------TKNTFDEERYQKWV
S---------------------KTGLNESTIDTLIQENSMELEHFKTVLS----------
-----------NKEHPELTTSLEWIAIVNKLI---------NDDTYYNKDIEYLDEFKNI
LFYTFYVPFFNYS---LEVISNKL--------KGIHEEKMSYITIETLKKNILSTVA-DR
ISGIGLKVLITE--IN-------MARTGDL-----L----SGENE--KER--YDSFMNDF
LQDKEYIQSLFNSYPVMVRLMVETVHSTVDAMFEIVYHYTEDRDQLIELF----------
----------GEDFNTLTSIDLGAG--DTHQNGRTVAMLNFT---NK-------GKLVYK
PRSLKTDELFNELLTWINK----------KGFKKPL-KNLTVLSRDEYGYQEFIT--GSE
CNTLQ-EVENFYYRQGGYIALFYILNSTDFHHENI-IADGEYPIFIDLETLFSNTI---E
FNNKLTDNKSAFMKLSLDIKDSVFQSLMLPAKFSDDPLI-----NYDLSGLGVSGELEVE
PSAVNALDNI-YSDQIK-MVKQTVKLQEF----NNTP-R-IKQKKTS-----ASEHVQEI
INGFTDMY-KL--ILNNKKEFTLENGPLYSFQE-TFARQVFRATEAYSRFVSASIHPEYL
KN---GVDRES-LFYYLW-----HGINLQPKFSRIA-KYEVQDLLRTDIPYFTFKVGSTS
LFS---ADKI--EIKD---FFDKTSIDIIKEKL-NKLSNADHDRQVEFIKLSL-----SA
IATNEQQEYTPYGFKEVEKSLLDTKNYHNNQ--FLNEAKKIGDEIVDRAIV------GDD
FKDALWFGL------NLDNNEQFKLSP--ISIDLYNGSLGIVLFLGILAKETNDEK-YKK
-------YA--VAGL----------NYIEEKVTHT-------NLHSTSAF--SGYSSIS-
YAY----AYLGKI-------WNDQKLIDKSREYITK----IDSLLIENETIY--------
--DFVGGLSSSLLVLVRL----YEKFN----FTELKPICDLIAQKL--------------
---------LNQASDQIKTNTLL--------------TGLAHGASGYAWPLLEYAYKMDQ
----N-----HLLN----DILTILDYENS-KVNVNQDNWL----------DLRGSENPDA
PAFW-CHGAGGIGTSRL---MMSQLIE---------DAT------INDDLQK-----CID
ILMTKGF--------GISH----TLCHGDFGNIDFL-LTYAQ---ITKNN--EYTKISRE
IGKYVLKQKEENG--------KWNFDQNG-----DVNIFGFM--IGTSGIG-FELLR---
LNNPD-----IPSVLSLDLP---------------------------------------
>NZ_ACLZ01000087.1|c1|26461-29586|-|ZP_04287189.1|Lantibiotic_mersacidin_modifying_enzyme
-----------------------------------------------------------M
TLQHGTYLLEREN---------------------------------KENIFDEERYQKWL
S---------------------KTGLNESIIDTLIQENNIELEYFKTVLS----------
-----------NKENPELNTSLEWIAIVNRLI---------NDNTYYNKDIEYLEGFENI
PFFAFYVPFFNYS---LEVISNKF--------KGVHEEKIFSINIENITKSILLTVA-DR
IGQIGLKVLITE--IN-------MARTGHL-----L----SGETE--KER--YASFINEF
LQDKEYIQNLFNSYPVMVRLMVETVHSTVDAMFEIVYHYAEDRDQLVAIF----G-----
-----------GDFNTLTSIDLGAG--DTHQNGRTVAMLNFN---NK-------RKLVYK
PRSLKTDELFNELLIWINK----------KGFKKPL-KNLTVLSRDEYGYQEFIS--GSE
CNTQQ-EVENFYYRQGGYIALFYILNSTDFHHENI-IADGEYPIFIDLETLFSNSI---E
FNNELTDNKSAFLKLSLNIKDSVFQSLMLPVKFSDDPLI-----DYDLSGLGISGELEVE
PSAVNALDNV-YSDQIK-MVKQKVKLKEF----NNTP-R-IKQKKTN-----ASDYIQEI
INGFTDMY-KL--ILNNKQEFTLDNGPLYAFKN-TFARQVFRATEAYARFVSASIHPNYL
KN---GIDREG-LFYYLW---HGINHQPKF--SRIA-KYEIQDLLRTDIPYFTFKVGSTS
LFN---SDKI--EIKD---FFDKTSIDVIKEKL-NKLSDIDHDQQVEFIKQSL-----GA
IATNEQKEYNPYGYKEVEKSLLDTKEYYKDQ--FLNEAKKIGDEIVNRAIV----G--DN
FKDALWFGL---NL---DNNEQFKLSP--ISIDLYNGSLGIVLFLGILAKETNDEK-YKK
-------YA--VAGL----------NYIENKLAHT-------KLQSTSAF--SGYSSLS-
YVY----AYLGKI-------WSDQKLIN-QSREYIN----KIDSLLIKNETTY-------
--DFVGGLSGSLLVLVRL----Y--------EEFNFTELKPICDLI--------------
--------AQKLLNQASNQIKTNTLL-----------TGLAHGASGYAWPLLEYAYKMDQ
----N-----HLLN----DILAILNYENS-KVNDNQDNWL----------DLRENESFDA
PAFW-CHGAGGIGISRL---MMSQIIE---------NTN------INGDLQK-----CIN
VLMTKGF-------G-TSN----TLCHGDFGNLDFL-LTYAQ---VTKNN--EYIKISRE
IGRHVLKQKEENG--------QWNLDQHG-----DVNILGFM--IGISGIG-FELLR---
LNNPN-----IPSVLSLDLP---------------------------------------
>NC_011527.1|c2|705015-707966|+|YP_002303280.1|lanthionine_synthetase_(lantibiotic
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MDFIELIKQSDSTSLLKWKTRITHSE-----------------KRETHLLILLS
ALFAHAEKFFLQLRNNHRTLSRII-------------------TEQTLTTVIQEDLT-RL
LLPLISRVCVYE--MH-------VATKHQK-----L----SGDTP--EKR--FDYFVSL-
FADPKTALSLFEKYSLLKKLIETVFQQYLQNQQELLQRLADDYEAICHLF----F-----
---------QKKSNYQLHNITSSAG--DRHNQGRCVAILELTNKKES-------IKLVYK
PRSLQIDQAFQQLLDWFNQ-----------HASVPL-YRQTILAKSEYGWCEFIT--YTD
CKDEN-DVTLFYQRMGLLLGISHLLASTDIHYENI-IAHGSHPVFVDFECTLRPVF----
--------EDNNHPSSEVPPHLVSDTLLLPGKFMTREDYN----GLDLSGIFMPDE-QET
PYRRMGWEKA-GTDEMV-LVREKGTLPAG----QNMP-R-LNGERVD-----PLRYAPMM
TDSFINCY-RL--ILEHKKELLSDHSPLNAFKN-APIRILFRATSVYAKLLFESYHPLLL
YE---EAKR---LEHFLW---LKENAKPLIFSEDIL-AAEIGDLLSNNIPYFSSTADGKT
AYS---AEKR--SLSL---AIRLSGLTRVKQHLTHHFNEKDLRLQLAIIENSF-----TA
LQLDQSGFLPREKKWSLKTPTLPAENIKNEA---LALAKKALDQLVDYAII--------G
EERIMWPSI---DL---VGIDAWSAGF--TDIDLYRGVAGVALAFAYGASINKNKT-YEK
-------IA--RLGL----NSII--DVLSTEKEKA--------IHSVGGF--SGLGGLI-
YAL----SIFNRF-------IPDKRIRP-TLATLLT----WADSFIEKDHTL--------
--DIVGGCAGFIASVIAA----RALID----SNTLMALLTIATDHL--------------
--------LTQYPEPDKLPDSLENKYSDQPL------LGFSHGITGFTWALAKANEFLHD
----K-----KIES----WIKNALAYERC-RFDAKKNNWP----DVRTAIREHAQTDNKF
MIAW-CHGAPGIGLARL---DMQTIWD---------DPL------MGQEIDR-----AMQ
TTFNEGF-------GFHT-----NLCHGDLGNLDFL-LEVSQ-----RNPSKNRQLAYQA
RAAFVVERIKKDG---------ISLQIKG-----TMPLPGLM--LGLAGVA-YQLMR---
IAKPQE----VPSILLLTNGS--------------------------------------
>NZ_AAUP02000001.2|c1|112636-115596|-|ZP_01946732.1|lanthionine_synthetase_C-like_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MIDIIEVIKASSPDATHQWKNLITALE----------------KREKHLLALLSS
LFAHAENFFLEIINETGSPLSQII-------------------TKQTLMDFIQRDLT-NL
LLPLISRVCIYE--MY-------VVAENHK-----L----QGETP--EKR--FDYFVSL-
LSDPKTALLLFEKYPLLKTLIDTVYQQYLENQTQLMQRLANDYKEICQFF----F-----
--------KKKIERPLFLTRITSAG--DRHNQGRCVSILEFSNEKDN-------FKLVYK
PRSLRIDQAFQQLIDWFNQ-----------KLSAQL-YCPKILLKPEYGWCEFIT--YTE
CKNKK-EVALFYQRLGILLGISHLLASTDIHAENI-IAHGSHPVFVDFECALRPLF----
-------KSDDQKPSPEVPPHLVSDTALLPARFMAREDYN----GIDLSGIFWPDE-QEA
PYRRMCWKKL-GTDEMY-LVREKSILPTQ----QNMPR--LKHDHVD-----PLSYEKEI
SSGFTRCY-QL--ILDHKKELLSDHSPLNAFQN-VPIRVLFRATVVYAKLLFESYHPLLL
YD---NDKRRD---HFLW---LKEHAKPLIFSEEIL-DSEINDLLSNNIPYFSCQADKEQ
VFS---PTHQ--QIAL---QFRFSGLERVKQHLIHRFNKNDLRLQLLIIENSF-------
MTLRLNRGLAYEKNIPVSDEIPSSSRNIKDE--AFMLAKKELDRLTDYAII--------G
DNRIMWPCI------EMVGSDAWSPAF--TDISLYKGIAGISLVFAYAASLFESKP-YER
-------IA--RLGL----------NSLIEVFSEQ--KKEAIVSMGVGAF--TGLGGLI-
YAL-------DQF-------IPDKRIRP-MLEILFT----WMDEFIEKDNIL--------
--DVLSGSAGFIPLLLSA----QSFIN----PKRKIMLLKKVAKHI--------------
--------LTQYPNPAKLFTGYKNPYANQPL------LGASHGAAGFIWALVKANYFLHD
----K-----NIEQ----WIKSALAYERS-HFDYEKNNWP-----SFQKQNREHYRGDKF
MTAW-CHGAAGIGLTRL---DSREFWQ---------DDL------IDEEIDR-----AIQ
TTLKEGF-------GLST-----TLCHGDLGNLDFL-LEASQ-----KNPSKKLQDIFHT
HAVFVVERIKKHG---------ISLDIRG-----TLPFPGLM--LGVAGVA-YQLMR---
VAEPQR----LPSILLLKLPTLW------------------------------------
>NC_009727.1|c2|1219782-1222751|-|YP_001424603.1|lanthionine_synthetase_(lantibiotic
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MIDIIEVIKASSPDATHQWKNLITALE----------------KREKHLLALLSS
LFAHAENFFLEIINETGSPLSQII-------------------TKQTLMDFIQRDLT-NL
LLPLISRVCIYE--MY-------VVAENHK-----L----QGETP--EKR--FDYFVSL-
LSDPKTALLLFEKYPLLKTLIDTVYQQYLENQTQLMQRLANDYKEICQFF----F-----
--------KKKIERPLFLTRITSAG--DRHNQGRCVAILEFSNEKDN-------FKLVYK
PRSLRIDQAFQQLIDWFNQ-----------KLSAQL-YCPKILLKPEYGWCEFIT--YTE
CKNKK-EVALFYQRLGILLGISHLLASTDIHAENI-IAHGSHPVFVDFECALRPLF----
-------KSDDQKPSPEVPPHLVSDTALLPARFMAREDYN----GIDLSGIFWPDE-QEA
PYRRMCWKKV-GTDEMY-LVREKSILPTQ----QNMP-R-LKHDHVD-----PLSYEKDI
SSGFTRCY-QL--ILDHKKELLSDHSPLNAFQN-VPIRVLFRATVVYAKLLFESYHPLLL
YD---NDKRRD---HFLW---LKEHAKPLIFSEEIL-DSEINDLLSNNIPYFSCQADKEQ
VFS---PTHQ--QIAL---QFRFSGLERVKQHLIHRFNKNDLRLQLLIIENSF-------
MTLRLNRGLAYEKNIPVSDEIPSSSRNIKDE--AFMLAKKELDRLMDYAII--------G
DNRIMWPCI---EM---VGSDAWSPAF--TDISLYKGIAGISLVFAYAASLFESKP-YER
-------IA--RLGL----NSLI--EVFSEQKKEA------IVSMGVGAF--TGLGGLI-
YAL----SVFDQF-------IPDKRIRP-MLEILFT----W-MDEF----IEKDNIL---
--DVLSGSAGFIPLLLSA------QSFIN--PKRKIMLLKKVAKHI--------------
--------LTQYPNPAKLFTGYKNPYANQPL------LGASHGAAGFIWALVKANYFLHD
----K-----NIEQ----WIKSALAYERS-HFDYEKNNWP----SFQKQNREHYR-GDKF
MTAW-CHGAAGIGLTRL---DSREFW----------QDD-----LIDEEIDR-----AIQ
TTLKEGF-------G-LST----TLCHGDLGNLDFL-LEASQ-----KNPSKKLQDIFHT
HAVFVVERIKKHG---------ISLDIRG-----TLPFPGLM--LGVAGVA-YQLMR---
VAEPQR----LPSILLLKLPTLW------------------------------------
>NZ_ABAG01000003.1|c1|146340-149375|+|ZP_01834975.1|lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
--------------------------------------------------MKDSMINYWL
N--------------------YFPEYSLETFEKELT-KHLGENYIEKLLN----------
--------FYKDYETVDVDIIFKYVSLNLEAI----------------PKQFKEIIEEKY
LFSSIIIPFISKY---FSEFSYTI------------SRNKSIEDSDEFLTYSVLDVA-DR
INTLLYRSIIGD--IS-------TLKARGV-----L----QGKTS--VNK--MDYYKNKY
IKEEKNLVDFYAKFSELTRLTSYVVKNTFEFYLEIIQQFQEQYVKILELF----Q-----
--------CKTDSKVLISKIELGNG--DSHKKNKSVSKIFLS---SG-------NTIIYK
PRSLNIEKSFEKMMEFLRD----------QNAILDY-KLPNIISTEKYGFCEYID--TEE
CMNDL-DVKGFYQRIGELLGILYSLNSVDFHYENI-IAKGAYPVPIDLETLIHPQI----
--VDRNNDLSAFKKASKKFESSVITTGLLPIFLK----------GNEVGGVSMNSE-QIS
TFKTDYIKDT-NSDNIH-IEREYYVISPK----NNNP-I-INGKIVD-----AKDYIFEI
IKGFQGIY-KW--IMNNRKIYI--EKIYELFSN-TVGRFIPRATLYYSQLLRISLSPEFT
QK---HFERKM-LLRRLY--------IGSENSETMLIDSEFKDLLEADIPYFSFIIGDNK
IFD---SKGV--EVKG---VNLTNFKEDFNSKI-STFCDEDLKEQIGYIKDSF-------
------ISRKNQSDSNDIKFQTYYNKLKPEL--WLSTATKIGDLIIDNSIE-GVNE--YG
RKDLAWISV---TMQG-FEEDVWLPSV--LTNDLYSGNAGISLFLINLWNITGKKR-FLE
-------YA--KKSV----ETSK--VLLGNKYIHS--------NHLVGAF--TGVGGMI-
YSL----AEIAHL-------TGDVKNKN-FIKKSIL----SLDELILRDTSN--------
--DLISGNTGLLAVILKL----VNSDSYYNTPDIKYVISKIVQKIL--------------
----------HESKFVDGLRFWECMPNRNY-------VGFSHGNAGIHSYLFKAMKYLGD
----S-----RAEE----ILQESLNYEKK-CFSSHKNDWY------------KSKDEKQI
SYTW-CHGSPGILLSKL---LLLSSGY---------NFD-----NLDNDIRL-----SIE
NTKAYGF-------G-NNP----TYCHGDLGNLEIL-NYASK---LLHKK--NLNNLCTN
IYQELFDTVLVKE---------WDKKNLK-----SSNTYGLM--VGLSGWG-YSMLS---
NYTDHS----LNNFLWLD-----------------------------------------
>NZ_ACPD01000003.1|c1|18151-21171|-|ZP_04803848.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
-----------------------------------------------MEDMISYYEKCWM
K-------------------------LYPEMKSIEELNTYLKKVFGKSLK----------
--------EKLQNERVEKVSVKEYNRNLKMFL--------------------DDNMLENM
RFSRFYGPIMVEY---IENLPKYI----EKTMIVKNI--------KLFMESMILQLS-DL
MCSIAFRTMVFE--IN-------NAKNKNL-----L----KGESP--EER--YKYFNNEL
LDDYQYRKSLYSEYCFLVETLDECAKNFVKYIEEILVNTSKNMCRIQSDV----N-----
---------SNIELGKLINIEFALG--DTHCRGKSVAKLIF----EN-------TIIYYK
PRNSIIDNKFQSVLNLINE----K----GILSGRKY-RVMNIHGTSECGWFENIK--YEE
CRSID-NVHDYYLKIGGLIGILYFFNATDFHHENI-IACAENPMLIDLESIFSVEM----
-KSKVFDENSAYNNAIEYLKSSVQSIGILPNKLHIGDLDD----KYETGGIVYKEK-QVA
PIKSLKVVND-ASDGIR-TELVNSIIEGN----LNAP-K-YNGNIIN-----PKEYVEDI
KEGFRLVY-KW--ILGNKKEFI--EFVETSFSE-TKIRIILKPTFMYAQINSIAKHPNFM
SS---EDENEL-INARIG---------IYADNIDII-KSEIRSLKRYEIPYFSALFNEEK
LFD---EDEN--VLES---RLIISPQLLFRNKV-CKATEIDLNNQIDFISISF-------
----LSKNPEELRTGIHYVEDA-VEIINTDS--YLNVAKEIGDYLYSIAII-GENQ--HG
KSDATWIGS---AVSK-IDVNDWTYSV--SDLDLYNGNSGIALFLLNLWKVTKDKK-YLD
-------LA--IQAA----ELII--SIIKNKTFNH--------STLIGGF--NGIGSYI-
YII----SKLVVN-------TNDEYFYS-TLIESID----LLEERIEAASEM--------
--DLVAGASGMLAVLLNV----YSEIDDKLIKEKVKPLLYMLFYKI--------------
--------QENVKSGGKLIRY----------------SGFGHGIAGCIPYLYKLYLIDEN
----R-----EVYQ----LFSELLSYERDHFYSKEEKDWV-----------MSDD-EVNY
SKAW-CHGAPGILLEKI---ILKELGY---------EDE-----YLDQEIKV-----ALN
NIKKKCI-------G-NNI----VYCHGDIGNLDII-QYAAK---ISKDE--KMIKECSN
TYDKLFQLHIKNN---------WNSEASA-----YSKCKGIM--VGVSGIG-LSLLR---
MINKYD----IDDFLWLS-----------------------------------------
>NC_012034.1|c1|1199942-1203064|+|YP_002572981.1|Lanthionine_synthetase_C_family_protein
-----------------------------------------------------MKQDNNW
LIYNLST---------------------------------------DKEFTFDDVINYWL
T---------------------LFPEIKKKEELEKLLQEISNTNFEKIRE----------
--------YYYSTEKHGEKFLGKYCNNIELVL---------------ELERLLAIIHNEY
KWVYFFKPIIRTY---FEYIYELT----QRSEFIHDK--------NEFMIQILKLAI-EN
LYKIAYRVLILE--LN-------IARIESK-----L----VGETP--EQR--ANYFSNIL
LRNDDYIEKLYMEYNELTRLMDLCMRNFCNYLREIIENTEREEKQLSKKL----L-----
---------DGKHLGKLKSIEFGAG--DMHNGGRSVAVLYFD---SG-------VKLIYK
PRALDLEVKFGEFIEWLNN----Q----CIPNFYSL-KTCRTYTIESAGWVEFIE--YKE
CCEID-EIKRFYYRAGEILCILYTLNARDMHFENI-IAEGENPVLIDLETLFHPDL----
-FDINRTETFASTEVLRILNNSVRGIGLLPTQIVNFKSGK----VFEIGGLCAEDE-QEA
PFHSLFVNNY-NTDEIK-IEYDYAIIKPK----SNNP-I-MKGKRIK-----SSEYVNEI
INGFVNTY-KW--ILKNKNEYI--KKVREKFQN-CKCRVIFKPTSIYAQLLATSYHPDLL
RN---SIDRKV-FLHRIG-------LVPYEEEKRIV-LSEIEDMLNGDVPYFTTFLNCNS
IIN---SKGE--KIEP---CYKQTPLDYVIKKI-ESMNEKDLERQVALINMSY-------
-LNKVTYDMGYHTNIRFKTCNN-IKKFDKQK--FLDIAKKIGDLILEKSIM--GKR--NG
KNERSWIGS---IG---IDDKFYFITD--VGYDLYSGNSGIALFLAFLGAITGSKK-YKL
-------AA--IEAM----VPVI--SYIENLGKVS-----NSKINRIGAF--SGVCGYF-
YAL----FHIGKC-------LDIKEFLD-IVYGKIG----ILSKAELITENH--------
--DIISGLSGTLGVLLSI----YDKT-AE--EKIREELLSICTKILYA------------
--------INEKSNKCKEGITWGEEGY----------VGYSHGNAGVTSQLIRLFYINHN
----S-----NIID----LIRLSLTYERN-MFDKRNNNWR-----------RSLL-EDGF
SFGW-CHGAPGILLSRI---NLIEKGY---------HDD-----YCFEEIKK-----AIE
ITKKYAF-------G-KDY----CLCHGDIGNLRIL-YYTAK---VLKDE--ELKISCLA
TLNEFLDRYFMGR---------WCNGEFN-----KIENYGLM--TGLSGVG-YAFLQ---
FCEYVQ----MPEILCLE-----------------------------------------
>NZ_ACGC01000076.1|c1|4915-8130|+|ZP_03930799.1|lanthionine_synthetase_C_family_protein
-------------------------------------------------------MKSIE
EFKNFAYSFERKDYELNF----------------------------KNYKIAKVRKKYWE
S--------------------FLGDDFINYEDYLLKAYNIDSDRFECILE----------
----ESNFKIKNTVEMKKIEKFLYYMQSQEYL---------EYKLPKFYVRNNKNKKVKP
LFYDFYKPFINVG---VINLKKCL---------------KFYNISEDIINQFTIQLI-NK
LINITYRTIILE--LN-------IAKENEK-----L----IGENK--YER--YEYFTEHY
IEEH--FWDILEEYPVMLRLMVEAVNNWVTATFEFIKHFYDDIHDLKKYF----F-----
------------ISDIITKVDLNIS--DSHNNGKSVIIVHSE---NG-------KSVVYK
PRTLELDEKFQETIKLFNR-----------LTNSNL-YTYKVIDKRDYGWSEYIS--YES
CSSEL-DMQNYYDELGKLLFILYVLRGNDVHYENI-IAHGKHPVLIDIETIFHNKM----
---VDKIHRGADDKIYETIENSVRRVGILPNIIWGRGKDI----GVDVSAMTNDES-KEI
PIETASILDI-LTDEMR-IDYKRSVLEKK----NNTP-F-IKNKVVD-----TFQYKQEL
KKGFINSYRQF--LSEDSKKIL--LKDVDKYNH-KESRQILRATQYYSSLIQLSFHPDFM
RS---GLDREM-LFSKLW-----TQVEEENKLKRIS-GIELLSLIKNDIPMFVSKIGTFS
IED---KDNN--KVEN---FYKETSINLVKKNI-ADISEEDLRFQILMITTAL-----NY
DPKYNFINNKELRHDRILKIIKKSSDLELKKSELIEISEKIANHLIELSYI-------GD
NNDISWMDM---NIVG-EKTNDWNIVP--VGMDLYNGISGILIYFIYLYKETKNHK-YFQ
-------VI--EQCF----ETIR--GYFNKRDKYK------DNKILFGGF--SGETPII-
YALIILEKELNEY-------FDSDELEL-MRSKIFN----SCEKSLINNQEH--------
--DVIIGSAGVILILLKY----YEHVK----DKKILSLAERYADKI--------------
---------MKDSIKIENALAWKSSFAKQPL------GGFAHGTSGIIFAFAKLYKYIKN
----D-----SYLE----IIEKGMKYEDM-LYRDSVKNWS--DRRETDDGIRYDDLENHI
PVAW-CHGASGILLSRLYIKNLEIPLT---------ESR---KSSIDSDISN-----AIE
TSLKFGF-------G-RSH----CLCHGDLGNIEIL-NYASR---VVEKR--KIKEKCDI
YMEYIKEDLMKGN---------WKCGIP------YDNSPGIM--VGLAGIG-YGVLK---
VYNPT-----IPSILILE-----------------------------------------
>NC_011900.1|c1|1236969-1240220|-|YP_002511204.1|putative_lantibiotic_synthetase
----------------------------------------------------MNRKLNIT
DFKDASYFSERKISSHDL----------------------------GDGLKSRKRKEYWD
N--------------------FIGEGSNEFWKYLQEKNDFSKHDLDIFLE----------
------EHTYDVKDIDSFSHMDEFIEFFFKRN----------DYTLPEFYIVDSEGKRKP
IFSNFVIPFLKFA---AYKLEDNL-------------SSQNLKVTRDVLNSLLIALF-QQ
ILNISYRTLILE--LQ-------VLKEQNM-----L----KGETG--EKR--FKYFSEIY
LSDH--FWDILKEYPVMFRLIIENIQNWVTNNVEFLTNLKEDKALLQEHF----S-----
------------INGELTKIESGVS--DFHNHGKSVYLLWFGT-----------NKLVYK
PRDLILDVKFQNLLSWYNL-----------KFNKNL-YVTNILNRGNYGWVEYIE--HLP
CTYES-DFIQFYTHLGYLLFLLFAMRGNDIHFENI-IAKGNRPVLVDIETLFHNTT----
--EYRKEYETADKLIFSLLEKSVKRVGILPNIVWGKDGNS----GVDISGLSSSAG-EMI
PIERASIMHS-MTDEMK-IGYEQSALQSK----DNQPFI-QSGKDVD-----LNSYKNYV
SAGFKEAY-EI--ISKDPSSIEEFLVEIEKFNN-AYSRQIMRPTQFYSNLIQTSYHPSFL
RS---GLDREM-LFSKVW-----KIVFEDKKVQRIA-SSEFESLLLGDIPLFQTKISDRF
LCS---------ELTKYQNFFNISGMELAIQQI-KDFCQKDMEFQLNLIETTL-NYDPSY
NLVQDSFVPLKPSVKVIRNLNQKEIQETKSR--IVPLTEKIADYLSKISYS-------GT
SGDICWVDM---NILG-EKTNDWNMVP--IGCDLYNGISGIMLFYLFLYLETKKKD-YLI
-------YL--KKCY----RSLK--YYLDSRKQFA-----THSQVLFGGF--SGETPII-
YVL----LLLKTR--------MPEHFNSDELDVYIY----DIIDDLKKGYRYDENF----
--DVLVGSAGAIIHLLNV----FEVTRDEELLILAHDLFSHLEKNS--------------
---------TKITVEGQDGRAWKGTMASNPL------AGFAHGVSGIVWALSKLSRYFPE
----DK----KLKT----IIKQGIIFENS-MFDTEKSNWS--DYRETESGIKYKDIVENI
PVSW-CHGAPGILISRL---ELYKNN----------TLNVEFRRTMKSDMDV-----AID
TTIKYGF-------G-KSH----CLCHGDLGNLNIL-FYVAK---KMSSE--HLYNVVYS
YLNTILDDLESEN---------WKCGLP------YKNSPSLM--SGIAGIG-LGLLT---
LNNLS-----IPSVINLEIW---------------------------------------
>NC_006322.1|c2|3949938-3953096|+|YP_093634.1|hypothetical_protein
------------------------------------------------------------
MNEKSAGYHERLPVAQ------------------------------TQSPLVNDKIKYWR
S---------------------LFGDDDKWLNKAVSLLSHDPLSSIAQSS----------
---------VSQSVGLKDSRRGPWQKMQKRIF------------ETPFSYKDSALQDSEL
LFDSLLTRFASAA---QDALEEQN-----------------IILSPPLCRQVLTHLK-QT
LLQIAHQTLILE--LN-------ILRLEDQ-----L----KGDTP--EMR--YLDFNDNF
LVNPGYLRTLFNEYPVLLRLLCTKTDYWVQNFSELWKRLRQDREQLQAAF----H-----
------------IAGDPVHIELGVG--DSHNKGKMAAILTYS---DG-------KKIVYK
PRSHDVDDAFQLLLSWIND----------RNSGSPL-KTLRLINKKRYGWSEFIP--HET
CHTKK-ELEGYYTRLGKLLAVLYSIDAVDFHHENI-IASGEHPVLIDLESIFHQYK----
--KRDEPGSTAVDKANYILSRSVRSTGILPFNLYFGRKNRDK--VVDISGMGGQEA-QES
PFQALQIKGF-FRDDIR-LEHDRFEIGEA----KNLP-T-LDHQHVP-----VADYLHCI
IEGFSAVY-RL--ISDHGESYL---ATIEHFKN-CTVRNILKPTAHYASLLNKSYHPDFL
RD---AVDREV-FLCRVE------KFEDADTDIAAA-KTELKELIRGDIPYFLSKPSDTY
LLN---GEEE--PIAA---YFETPSFTRVIKKI-SSFSDQDLKEQANVIRMSI-------
--LAAYNARHEKDAIDIDQNHP-SPRSGALQ--PLAIAEKAADDLAEKRIE----G--ND
GKDVTWIST----VIEGVEEISWTISP--VSLDLYNGNAGIGLFMSYLSRFAKRPETYSH
-------IT--EQCV----FAIQ--RALNELKEKE----EFLKYADSGAF--TGVSGYL-
YFL----QHAGTV-------QKKNEWIE-LIHEALP----VLEAVIEQDENC--------
--DIISGSAGALMVLMSL----YEQLD----DPVFLKLAEKCAGHL--------------
---------LQHKTNIENGAAWKDPHTQNYY------TGFAHGTSGIAAALSRFNKVFDS
----Q-----SLKK----IISQCLAFEKQ-LYIASEKNWG-------------SKGREQL
SVAW-CHGAAGILLSRS---ILRENGV---------NDP-----GLHTDILN-----ALE
TTVKHGL-------G-NNR----SFCHGDFGQLEIL--------RGFREEFSELNTIIQN
TEDRLLTYFQENP---------FSKGVSR-----GVDSAGLM--LGLSGVG-YGMLQ---
CQYGEE----LPELLQLSPPQALIKKNSKAFKRENVF----------------------
>NZ_ACLZ01000087.1|c1|75-3215|+|ZP_04287168.1|Lantibiotic_mersacidin_modifying_enzyme
-----------------------------------------------------------M
SVKHSAFIDEIKTND-------------------------------QIVPYSTDYINYWK
K--------------------TFENNENKFEGILKDLSGIQLSTLSQLEH----------
-----DEYSVDKVDALLSLTFSEFDSFQTYEF-----------------SPTIEEHLSKA
TFYNFFKKFMSYS---FSKVHKSL--------------NTYSFFEESQLLAPLEYMY-KR
LYELSHKTLILE--LN-------IQRVLEN-----L----KGETS--EER--YNHFCSY-
ISTNEFFVYFKDTYPALYRTMLTTLIHWSNNIITLYYNLEQDKVQIQETF----N-----
---------IDMQTNKLMTITLGLG--DEHNDGKTVSLIEFL---PN-------IKLIYK
PRSIGVEAAFNDLTAWINN---------QVNNKAQL-YSPKIIDKHSYGWVEYIE--NIE
CKTEE-QLKSFYFKMGSLLGVLYSLNAVDFHYENI-IAMGEYPVPIDLESLFHHAK----
--ILEEKNGSAHNKALNLINRSVRSTGIIPFLAFNSDNPNYK--GLDLSGLSDKNH-QLY
PLKVPSVEAK-NTDVMH-VDATYKYVKVNEFE-KNKP-I-FKGEKVS-----YKDHVDVI
IDGFKYIY-EW--ILNNKQQYS--NYISDKFKN-TIVRMILRPTAVYGELLRKSKHPDFL
QK---GYNRDI-YFHTLA-------LEPENKPKEII-KSEKTDLLNDDIPYFYTTVSSNH
LYH---REKI--CIQN---YFESSPLEAVIQKI-DDLNIVDCSQQIRIMRMSF-------
----LAHSATFGANEQAIDPYRKVHIHANKSKEFLIEARHIGDYLIANAIE------GDN
QSDLCWIST----VISASNEYKWDIYP--VDLDLYNGLSGISLFFSYLYHLTGRND-YKL
-------TA--EKSI----YPVI--NSLQRLPEQR--------MFNIGTF--SGVSGSI-
YAL----NHINQL-------SHTKQYEQ-LILDSMK----MVVSKLSQDKVF--------
--DIIDGTAGVIGVLIAL----YKDSG----NKEYLKLLNQASEYL--------------
------VNAAYHHPGKEGHVSWKQRDDISW-------IGYSHGTAGIITALVAANQYINN
----P-----NILK----LADKVLSYENS-FYDPKHKNWK-------------LPSKDNH
SVAW-CHGAPGILLSRL---MLKESNY---------ESS-----ILDQNIYA-----ALD
TTIDKSF--------GHNR----SLCHGDFGNLDIL-LYAAK---VLQDK--TSYERANS
IGIQLLEYSKTHN---------WKQGVST-----GTESFGLM--TGLSGIG-VGLLQ---
QSDYNS----IPSILRLEEAKL-------------------------------------
>NZ_ACMW01000278.1|c1|68-3208|+|ZP_04160683.1|Lantibiotic_mersacidin_modifying_enzyme
-----------------------------------------------------------M
PVKHSAFIDEIKIND-------------------------------NIVPDSTDYIHYWK
R--------------------TFGNDENKFKKILKDISGIPLANLSKLDQ----------
-----DEYNVQEIDALLSLTFSEFDSFQTYEY-----------------SPTIEEKLSKL
TFYGFFKKFMCYS---FSKVHQSL----NTYSFFE----------ESQLLAPLEYMY-KR
LYELSHKTLILE--LN-------IQRVLGN-----L----KGETP--EER--YTHFCSY-
ISTNEFLVYFKDTYSALYRTMLTTLIYWSNNITTLYYNLEQDKAQIQENF----N-----
---------IDIQTNKLITVTLGLG--DEHNDGKTVSLLEFL---PN-------MKLIYK
PRSIGVEAAFNDLTAWINN---------QVNDKAQL-YSPKIIDKHSYGWVEYIE--NIE
CQTEE-QLKSFYFKMGSLLGVLYSLNAVDFHYENI-IAMGEYPVPIDLESLFHHAK----
--ILEEKDGSAHNKALNLINRSVRSTGIIPFLAFNSDNPNYK--GLDLSGLSDKND-QLY
PLKVPSIESK-NTDVMH-IDAKYTFVKVNEFE-KNKP-I-FKGEKVS-----YKDHVDVM
IDGFKYIY-EW--ILSNKQQYS--NYVSDKFKN-TIVRMILRPTAVYGELLRKSKHPDFL
QK---GYTRDI-YFHTLA-------LDPENKPKEVI-KSEKTDLLNDDIPYFYTTVSSNH
LYH---REQI--CVQN---FFESSPLEAVVSKI-NDLNSVDCSQQIRIMRMSF-------
-LAHSATFGANEQTIDPYLKVN-IHANKSKE--FLTEASHIGDYLIANAIE--GD----N
QSDLCWIST---VISA-SNEYKWDIYP--VDLDLYNGLSGISLFFSYLYHLTGKQD-YKI
-------TA--EKSI----NPVI--NSLQTLSEQR--------MFNIGTF--SGVTGSI-
YAL----NHINQL-------SQTKQYEQ-LILDSMR----TVVGRL-----SQDKVF---
--DIIDGTAGVVGVLISL----YKNS-SN--KEY-LKLLTQASEYL---INT--------
---------AYYHPEKEGYVSWKQRDDISW-------IGYSHGTAGIITALVAANQYINN
----T-----NILE----LADRVLSYENS-FYDSKHKNWK------------LPS-KENH
SVAW-CHGAPGILLSRL---MLKESNY---------ENS-----IIDQNIYA-----ALD
TTIDKSF-------G-HNR----SLCHGDFGNLDIL-LYAAK---VLQDK--TAYERAHS
IGIQLLESSKTHN---------WKNGVST-----GTESFGLM--TGLSGIG-VGLLQ---
QYDYNS----IPSILRLEEVKI-------------------------------------
>NZ_ACMG01000140.1|c1|1343-4336|+|ZP_04248715.1|Lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MSNLEVGTIINLQRNDLTWKYQWEELL---------------KGTVEDRFSTTSP
LFSGFVERFLLLA---IDLLEKQG--------TIRGLDSHILHTSNSFFESLLPSLF-QK
IIDFSYKTLILE--LN-------VLSDQGL-----L----QGETS--EKR--YQYFENL-
LHDKEYLRQLANEYPELIRSLLRITEKWASHVSEVLNRFTADYSKIVSHM----P-----
---------EVKQFGKLVRLHIGVG--DTH-DGRSVTMLEFT---TG-------CKLVYK
PRSLRVDKGYYRILSWMRQ------------FGVPYMKIIENIDCGSYGWTEFVE--FSE
CKSLE-EISEFYKNMGVNLAMMYMFNATDFHYENI-IAHGSSPVVIDLESLFHRHI----
--SKKEFEHDANGHAYEILYYSVMSSGMLPQYIYNSETYS----GFDISGIFGSGG-KKV
PNAVSLVDR--GTDRMR-LERGMGESGKT----HNLPH--YNNEVVD-----SYRYINDI
EQGFAQAY-RI--MMENKHRLK---EMIREFDD-VRVRVIVRNTRAYGELMRTLYHPDLL
RD---ELDRKV-VLHRLW-----LQCLADPKHLKFV-PYEMRDIEDGDIPIFYTCPSERD
AWA---SNGE--RIPQ---LFEQSGIDIVINKI-DKMGEKDLKEQLQLLNMSV-------
--LASKPDLYSYRIPEIQLKDSNDALGSNWKAEYVRLATAIGENLVQSAII--PSN--TA
ADDITWIGL----VASGEDERKLRLIP--VGNDLYNGNSGIALFLGYLSELTANNQ-YKN
-------IA--RKAL----QPLL--EIMRDKCRSN------AVSLNIGAFEAGSIGGGV-
FAT----YQLSRL-------WNDEELLQ-IVKEYLP----YYCELVDKDTAF--------
--DYIGGAAGAIDVLLHI----YHGTG----WTEALQGAEKCAEHL--------------
--------LQNAQTLPDGSMAWLTTPNRKPY------VGYSHGVSGIIASLSSLYRVTQR
----A-----EYIE----YIEKGLQYERA-NYCAELKNWV--------------TPNDTA
RVTW-CHGAPGILLSRL---RLLENGY---------WDA-----HIDQEINI-----ALE
TTLKLGF-------G-TEP----VYCHGDFGQLEIL-LYANS---VLDRN-EDTINVVRA
YLLRLLNNQQWNN-----------TGVHR-----AFDIKGLM--GGLSGIG-FGLLK---
QAFPEK----VPNILNLENDKFFSDVSG-------------------------------
>NC_009328.1|c3|2187465-2190545|-|YP_001126159.1|lantibiotic_mersacidin_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
---------------------MNEIVENNLMEIIKDKLLYPSEKKKEIEN----------
--------NVPINELLFQEKTNKWIDLFYQYL-------NVCKNNIEVDQLYSNEENLSN
PFSSFFKEFLEIA---SRYLDSSL-----KSQVNNYDDLSRICNLTSIKNDIMKFIH-EN
LVYVSIRTLIQD--LN-------EEREKGN-----L----IGDTP--KER--YNFYVDQI
LSSPDKKFELIKKYPVLVRILIEFILNKIDSIVESIYRFLKDRSELVHIF----------
---------HLSDDDILTSLTLQSG--DSHNNGRSVIIFQFS---SK-------KKIVYK
PRSLSIDLHFQQFLEWING----------KKPSLQL-KTITILNKDQYGWQEFVE--YKP
CSSNN-ELSRFYERQGNYIAILYILNATDFHFENL-IANGEHPVLIDLEGLVQNTV----
--KLPRKASSAYDIAFSKLTDSVLSTGMLPATFMQANIY-----DFDLSGLGGDEG-QPT
GLETFTIENP-LTDEMR-VIKVPAFSQSS----KNKPYL-KEEKEIA-----VTDYSSEI
IKGFREMY-TL--LLHNKKELLSQNGPIYLFKG-DKVRIILRSTQVYSTFLDSSFHPDYL
KD---GYERER-LINFLW-----IGKENHPEYQDAI-MYECRDILNGDIPYFYCYTDSSD
LYH---PIGI--VKHN---FFYESSFNSLLEKV-KMINEEDLNFQIEILTNSL------L
AQYSNKTHSHANVSNRVYNLDKISGNFRRES--FLEVSEKIADNIKENAIF-------GK
ENDVTWLGL------NLTIEDKWTFKP--LDFDLYDGVLGIGLFYANLYNLNKRKE-YKI
-------LA--EKTV----QTAL--NYLEYYPAKL----------PLSAF--YGYGAYA-
YVL----GNFSII-------FNNSEYLT-YVKKVLN----KAANTIEDDQLL--------
--DFLGGAAGLIIVCIHL----YKKTG----EQYLLDIANKCGELL--------------
---------LRKKEKQAMGIGWRPNQVNKPL------AGLAHGSSGFTWALMALYKFTKN
----Y-----NYKE----TFLQSFEYEKS-LFNKKEENWL----------VLSDDGDYYG
NSMW-CHGAAGIGMSRI---MMSEYYN---------SHD------LKNDIEI-----AIR
QTLKSGF--------GGTH----CLCHGDLGNLDLF-LLASS---KFKNE--EMKETALK
IGEYIASDITYGN---------LKYGTPS-----GTKNLGLM--LGQAGIG-YGFLR---
LAYPEI----VPSVLTLQLNH--------------------------------------
>NZ_ABVH01000020.1|c1|12075-15155|-|ZP_03149642.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
---------------------MNEIVENNLMEIIKDKLLYPSEKKKEIEN----------
--------NVPINELLFQKKTNKWIDLFYQYL-------NVCKNNIEVDQLYSNEENLSN
PFSSFFKEFLEIA---SRYLDSSL-----KSQVNNYDDLSRICNLTSIKNDIMKFIH-EN
LVYVSIRTLIQD--LN-------EEREKGN-----L----IGDTP--KER--YNFYVDQI
LSSPDKKFELIKKYPVLVRILIEFILNKIDSIVESIYRFLKDRSELVHIF----H-----
----------LSDDDILTSLTLQSG--DSHNNGRSVIIFQFS---SK-------KKIVYK
PRSLSIDLHFQQFLEWING----------KKPSLQL-KTITILNKDQYGWQEFVE--YKP
CSSNN-ELSRFYERQGNYIAILYILNATDFHFENL-IANGEHPVLIDLEGLVQNTV----
--KLPRKASSAYDIAFSKLTDSVLSTGMLPATFMQANIY-----DFDLSGLGGDEG-QPT
GLETFTIENP-LTDEMR-VIKVPAFSQSS----KNKPYL-KEEKEIA-----VTDYSSEI
IKGFREMY-TL--LLHNKKELLSQNGPIYLFKG-DKVRIILRSTQVYSTFLDSSFHPDYL
KD---GYERER-LINFLW-----IGKENHPEYQDAI-MYECRDILNGDIPYFYCYTDSSD
LYH---PIGI--VKHN---FFYESSFNSLLEKV-KMINEEDLNFQIEILTNSL------L
AQYSNKTHSHANVSNRVYNLDKISGNFRRES--FLEVSEKIADNIKENAIF-------GK
ENDVTWLGL---NL---TIEDKWTFNP--LDFDLYDGVLGIGLFYANLYNLNKRKE-YKI
-------LA--EKTV----QTAL--NYLEYYPAKL----------PLSAF--YGYGAYA-
YVL----GNFSII-------FNNSEYLT-YVKKVLN----KAANTIEDDQLL--------
--DFLGGAAGLIIVCIHL----YKKTG----EQYLLDIANKCGELL--------------
---------LRKKEKQAMGIGWRPNQVNKPL------AGLAHGSSGFTWALMALYKFTKN
----Y-----NYKE----TFLQSFEYEKS-LFNKKEENWL----------VLSDDGDYYG
NSMW-CHGAAGIGMSRI---MMSEYYN---------SHD------LKNDIEI-----AIR
QTLKSGF-------G-GTH----CLCHGDLGNLDLF-LLASS---KFKNE--EMKETALK
IGEYIASDITYGN---------LKYGTPS-----GTKNLGLM--LGQAGIG-YGFLR---
LAYPEI----VPSVLTLQLNH--------------------------------------
>NC_013093.1|c18|5846003-5847709|-|YP_003102580.1|putative_lantibiotic_modification_protein
------------------------------------------------------------
------------------------------------------------------------
-----------------MSGARARPDTHGVVAEAVAARGLPSPTAGASDP-------AGP
RAHTPDELAAVAAAVHWTPPDHRWPAPAEVVP-----APPPEPVEPVAADLCGREGDPPL
GLLGLVFPAARAA---RDAAVRDV----------------RGLGLPGLARAVGASAPVAE
LHQAVLRAVLTD--LD-------RDRRAGV-----L----LGDTP--QAR--HEWFCAR-
LATPAGRRAVWDRYPLLAHHVRALCGRWRRAVVELARRLAADRPRPGGLV----E-----
-------------------LRLGAG--DGHRGGRGVAVAVF----EG-------GTAVYK
PRPADADLLFADLVDWFGS----------TGPRERL-SSPAVRPHDGYAWAEFVE--HRP
GHDRG----AYHRRAGALLALLYAVLGSDMHHENV-VARGDEPVLVDLETLCTPIG----
----------------RVADWTVARTGLLHRG------------PADISGLGGGDA-GPD
PVTSLSPRDK-GLDTAH-LVWAPAVRAEP----LPNRQV-VAGERVA-----PGAHVDSV
VEGFADAY-DR--LARARPLLLSADGPLRALGS-ARLRVLLRPTVAYGRLLADRAHPAHL
VP---GAPP--------W--------TPLDPAGDPVVACENAQLAEGDVPLFEFTPDRRD
LLG---GDGA-------------------------------------VLRGAL-------
----------------------------RRE--PRRGVEEVLERLSDADLE---------
------------------------------------------------------------
-----------RQAA---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------EIRA----------------------------------------------
--TW--------------------------------------------------------
------------------------------------------------------------
--------------------------------------------PG--------------
-----------------------------------------------------------
>NC_002570.2|c1|482858-486037|+|NP_241321.1|lantibiotic_mersacidin_modifying_enzyme
----------------------------------------------------------MR
ELQNALYFSEVVFGPN------------------------------LEKIVGEKRLNFWL
K---------------------LIGEDPENLKEFLSRKGNSFEEQTLPEK----------
-----EAIVPNRLGEEALEKVREELEFLNTYS--------------TKHVRRVKELGVQI
PFEGILLPFISMY---IEKFQQQQ------------LRKKIGPIHEEIWTQIVQDIT-SK
LNAILHRTLILE--LN-------VARVTSQ-----L----KGDTP--EER--FAYYSKTY
LGKREVTHRLYSEYPVVLRLLFTTISHHISFITEILERVANDREAIETEF----S-----
---------PCSPIGTLASLHLNSG--DAHHKQRTVTILEFS---SS-------LKLVYK
PRSLKVDGVFNGLLAFLND---------RTGEVIKDQYCPKVLQRDGYGYVEFVT--HQS
CQSLE-EVSDFYERLGSLMSLSYVLNSSDFHFENI-IAHGPYPVLIDLETIIHNTA----
--DSSEETSTAMDRAFRMLNDSVLSTGMLPSSIYYRDQPNMK--GLNVGGVSKSEG-QKT
PFKVNQIANR-NTDEMR-IEKDHVTLSSQ----KNLP-I-FQSAAME-----SVHFLDQI
QKGFTSMY-QW--IEKNKQEFK---EQVRKFEG-VPVRAVLRSTTRYTELLKSSYHPDLL
RS---ALDREV-LLNRLT-----VDSVMTPYLKEII-PLEVEDLLNGDVPYFYTLPEERA
LYQ---EASA--INST---FFTTSIFHKIDQKI-DKLGIEDHTQQMKILHMSM-------
-----LASNANHYADVADLDIQKGHTIKNEQ--YVEMAKDIGDYLMELSVE--GEN--QG
EPDLCWIST----VLEGSSEIIWDISP--VGEDLYNGSAGVALFYAYLFKITGEKR-YQE
-------IA--YKAL----VPVR--RSVAQFQHHP--------NWSIGAF--NGASGYL-
YAM----GTIAAL-------FNDERLKH-EVTRSIP----HIEPMIHEDKIY--------
--DFIGGSAGALKVFLSL----SGLFD----EPKFLELAIACSEHL--------------
---------MKNAIKTDQGIGWKPPWEVTPL------TGFSHGVSGVMASFIELYQQTGD
----E-----RLLS----YIDQSLAYERS-FFSEQEENWL-------------TPNKETP
VVAW-CHGAPGILVSRL---LLKKCGY---------LDE-----KVEKEIEV-----ALS
TTIRKGL-------G-NNR----SLCHGDFGQLEIL-RFAAE---VLGDS--YLQEVVNN
LSGELYNLFKTEG---------YQSGTSR-----GTESVGLM--VGLSGFG-YGLLS---
AAYPSA----VPSILTLDGEIQKYREPHEANH---------------------------
>NZ_ABYB01000199.1|c1|6414-9728|+|ZP_04695268.1|lanthionine_synthetase_C-like_protein
------------------------------------------MPDDASEHPTVRPAGAHL
PWRRAATLSERLAGTPSQ----------------------------TDPVRGEKRLAMWR
E-------------------LAPLTGELSTLDTRLEPLGVDTDRLTALLG----------
--------EDDASLAARMADEPDWHRTFRRWW-----------AEGMATTDATRRLDPDM
GLLEVIRPLVEGAVHELDALVEEA---------VRASDDPVMADPGHILDIVRATAPAAD
LLSHVQRTLVLE--LN-------IARVEDR-----L----VGETP--EER--FASYVEL-
LRSEGNALAIWDEYPVLARLIVGQLRFWIDTRAELITALVADLPVLRETL----L-----
---------AARPPQRLDRLEFGAG--DKHRRGRSVAMVEF----DT-------CTLVFK
PRSLAMDTAFDGLLAWVGR----------QNPTHDL-ARIGILERGDHGWVEEVD--TTA
TTDAA-GGDRYAWRLGALTALLYLLHATDFHFENV-LAAGEYPVLVDLEALLHNDK----
-TAAVVKIDGETDIAAVTLADSVQSVGILPNHLLVRGEDGTF--GLDVSGLAGHGG-QLT
PMPVPIWEDS-GTDRMR-LVKRRMEMDAE----RNHPMT-ADGEPID-----LVGRVDAF
VEGFTHVY-RL--LETGRDELLAPEGPLAAFGA-VRTRLIARPTHIYGRLLLESTHPDFL
RD---GLDHAR-SLARLA-----GGHVEMPESRNAMVLDEIAELTLGDIPMFTVDADSGT
LRG---------GLDGEPIGTRYPPLTAVRERL-AALGDADLAFQERVIRSCV-------
---AATAMGESDARWPNWHRPRMDGAADPGD--FADEALRLAHRLADLCVR--------D
AHGLGWIGL------DLVDEKYWQYAP--APIGLYTGTAGIAHALDAVAAVTGDER-TGE
-------LA--RAAF----DQVAKRSVLIAETLAGLAKKPGADEFGIGAF--GPFGGAI-
YAL----AHAAVR-------HDRPEYAE-AAATLLP----AIDELVEEDPLL--------
--DIVSGSAGAILALLAL----ETARP----GTGAARIAERCAERL--------------
---------LATRQETADGWGWATPINPEQPL-----AGFSHGASGIAYAFARLDRVTPR
----A-----EYRE----AVRHALTYERT-VFDPELRTWR--------DLRPANLGGRTV
MNAW-CHGAPGIAMARNAFQELGTAPE---------LAD-----LIERDRHT-----AVL
AAISTGL-DLDPVSGLGNH----SLCHGDIGNLLII-DAATR---ADQEP--EVAGLLPK
VWKTLLHEGRENG---------WLCGVPK-----GVETPGLM--TGLAGIA-WGLAR---
KAAPER----VPDLLTLAAPDTGRTTC--------------------------------
>NZ_DS999644.1|c6|4445763-4449002|+|ZP_06586193.1|MrsM_protein
------------------------------------------------------------
-------MSERLAGTPSQ----------------------------TDPVRGEKRLAMWR
E-------------------LAPLTGELSTLDTRLEPLGVDTDRLTALLG----------
--------EDDASLAARMADEPDWHRTFRRWW-----------AEGMATTDATRRLDPDM
GLLEVIRPLVEGAVHELDALVEEA---------VRASDDPVMADPGHILDIVRATAPAAD
LLSHVQRTLVLE--LN-------IARVEDR-----L----VGETP--EER--FASYVEL-
LRSEGNALAIWDEYPVLARLIVGQLRFWIDTRAELITALVADLPVLRETL----L-----
---------AARPPQRLDRLEFGAG--DKHRRGRSVAMVEF----DT-------CTLVFK
PRSLAMDTAFDGLLAWVGR----------QNPTHDL-ARIGILERGDHGWVEEVD--TTA
TTDAA-GGDRYAWRLGALTALLYLLHATDFHFENV-LAAGEYPVLVDLEALLHNDK----
-TAAVVKIDGETDIAAVTLADSVQSVGILPNHLLVRGEDGTF--GLDVSGLAGHGG-QLT
PMPVPIWEDS-GTDRMR-LVKRRMEMDAE----RNHPMT-ADGEPID-----LVGRVDAF
VEGFTHVY-RL--LETGRDELLAPEGPLAAFGA-VRTRLIARPTHIYGRLLLESTHPDFL
RD---GLDHAR-SLARLA-----GGHVEMPESRNAMVLDEIAELTLGDIPMFTVDADSGT
LRG---------GLDGEPIGTRYPPLTAVRERL-AALGDADLAFQERVIRSCV-------
---AATAMGESDARWPNWHRPRMDGAADPGD--FADEALRLAHRLADLCVR--------D
AHGLGWIGL------DLVDEKYWQYAP--APIGLYTGTAGIAHALDAVAAVTGDER-TGE
-------LA--RAAF----DQVAKRSVLIAETLAGLAKKPGADEFGIGAF--GPFGGAI-
YAL----AHAAVR-------HDRPEYAE-AAATLLP----AIDELVEEDPLL--------
--DIVSGSAGAILALLAL----ETARP----GTGAARIAERCAERL--------------
---------LATRQETADGWGWATPINPEQPL-----AGFSHGASGIAYAFARLDRVTPR
----A-----EYRE----AVRHALTYERT-VFDPELRTWR--------DLRPANLGGRTV
MNAW-CHGAPGIAMARNAFQELGTAPE---------LAD-----LIERDRHT-----AVL
AAISTGL-DLDPVSGLGNH----SLCHGDIGNLLII-DAATR---ADQEP--EVAGLLPK
VWKTLLHEGRENG---------WLCGVPK-----GVETPGLM--TGLAGIA-WGLAR---
KAAPER----VPDLLTLAAPDTGRTTC--------------------------------
>NZ_ACMX01000081.1|c1|737-3958|+|ZP_04153727.1|hypothetical_protein
-------------------------------------------------------MLANQ
ALKKAFFIEERVQKSTTSNLAQEM----------------------QPDDYSNLRISNWI
D---------------------GMGNNEDLFLKNLHLHNIEHKDLHKIMI----------
------------SNNYDSDSSAEWLSIIGELE---RFNYQEPELPRILQKIIALNPNEPI
AFFNFLLPFLKIG---VERIEKAI--------SLSEKKHGISLSKEKVLFQLVRNLA-ET
LSKVSFRTLTLE--LN-------IARLKEL-----L----VGETP--QER--YKYFSYTL
LTDKNYLAQLYKQYPVLVRILSRKTIRWADNFAEIYDHLLHDKKAIEQHF----F-----
---------NSTPITVIEDIKTNIS--DSHNGGKGVVIIKFN---DD-------MNLVYK
PRSLKIDEQFQQLLCWFNE---------LKEKKLRL-LPITLLDRDTYGWSEFIE--HKE
CSAEQ-EVKNFYRRMGYYLALLYSINAIDFHNENL-IASGEYPMLIDLETLFNQDA----
--VQSTESVTAQEVALKTLSQSVLATNILPVFTLYNKIEGR---GLNISGMANGEE-QIY
PSKVPVIQSN-NTDEQK-VERGYMKIPAS----SNYP-T-LNGKQVS-----VTMYVDDM
MAGFKEAY-DL--LTKNKDCLK---NEISRFKN-TRVRQILRATNRYGNLLAISYHPDYL
RD---GLDREM-LLGKLW-----LDTEMQPELTQVL-LAEKADLLEGDIPYFTTEPGQPH
IYD---SQGR--CYEN---YYKTSSLAKTLDKI-ERLGPKDYEEQLQIIKLSM-------
----LALESSPSDKKSNYIPSVPDNQIDRDS--FLEEAKRVADYLISRSIQ--GTN--NG
KEDVSWIGT---RLTD-NAESLWRIAP--LGNDLYDGISGIALFFGYLYKYTRDSK-YRV
-------YI--QKCL----PPIK--ESLQELLAYP-------KYASLGAF--TGVLSNI-
YTL----NHLTKI-------LDEPSLME-EVKKVMP----KLIESIPYMQEV--------
--DIIDGSAGSLIVCLDL----YKQTG----DEIFLEASKKFGEHI--------------
---------LQKAIPQATGIGWKISVSEDAL------PGFSHGTSGIVWALHELYQLTGE
----Q-----MLYD----ALKQGLAYERS-LYMEEKRNWA----------LPSAAELPQL
PCAW-CHGAAGVVLSRL---LLKKAGY---------SDS-----LIDIEIRV-----GLE
TIIKEGF-------G-RDH----SLCHGDTGNSAVL-LLASK---VLKED--LWKQYSYA
VGEHVLDEIQQGG---------WKSGLPQ-----YLETYGAM--VGISGVG-LGLLK---
LYDING----VPSITHLESITALK-----------------------------------
>AJ250862.1|c1|6891-10079|+|CAB60261.1|MrsM_protein
---------------------------------------------------MHTKFKRNS
VWNRSSSISERKVRRSLNT---------------------------NWDELTNRRFERWK
S--------------------LVESDEGIRIEDVLATQNIDEETLKHTIN----------
---------AKEVEFINEGDHQGWLEIIQLVD-------------EQSYKNVNIEVRKDI
LFFSFIKPFLKIA---RGKLEEVL-------YSHSTKSLIKEELSPSVIDDLLNNLG-ET
LSAISSRILILE--LN-------VARVSGK-----L----RGETS--EER--ASYFNQAL
LNDPAYVRSIREEYIVLTRLLATKTMYWIQNTSDLLVRFHQDKGILESEF----S-----
---------NGQKLGKIISIDTGSGVSDTHNKGKTVAILNFE---TG-------IKIVYK
PRSLEIDVKFNKFVNYLNG----------KNLSFDL-KTVHTLNKKSYGWTQFIS--YKE
CQEEL-QIGKFYWRIGSYLAILYAMNAVDFHMQNL-IADGEYPILVDLESLFHNNS----
----TYTDTSAFSRAQEHIERSVLRIGLLPRKINSKAGFE----GIDLSALGAQEG-QVS
PHKTSTIVDR-DKDTVR-IEEKNFPIPVS----QHRP-M-LHGQIIN-----TVAYEGNI
IKGFEETY-FL--FMKYKQDML---EQIDSFKG-VTVRQILRGTSRYANLLKISLHPDFM
RD---GLDREM-ILDKLW-----LDTKLNPRLNQVV-NSEKEGLFLGDIPYFTSKPESTN
MWD---SSGR--KINN---FFKTSALNETKEKI-NEMNESDCHEQVSFIKTAI-------
-----LVIKDSYRKHKVFDINPRLHVFNPKD--FFQEAIKIGDFLASRAIE-GEQL--DG
QEDVSWIG----SFVDNQREDQFKISA--ANSSLYEGVGGISLFLAYLGRLSNNEK-YTK
-------LS--KKAL----------VAVHKNMSAS---------SDLGAF--GGIASYL-
YLL----DHLSKL-------WNDEQLLKNELYSALN----KLDSLIERDENN--------
--DILTGVAGTAVILINL----FKRYK----EEQILNLITKCGNRL--------------
---------IQNINVMEKGVGWKVPANPTPA------SGFAHGASGIIWALYEIYAITKQ
----T-----VFKE----VAEKALEFERT-LFIPEKNNWA-------DIKLENGQFRNDN
FVAW-CNGAAGIGLSRI---LILPHN----------QNE-----LIKDEAHV-----AIN
TTLKYGF-------E-HDQ----SLCHGDLGNLDIL-MYAAE---NFNKK---LSVNVTE
LSHKILNDIKLRG---------WLTGFEK-----NNESPSLM--MGYAGIG-LGLLK---
IFAPVE----VPSVLRLQSPLELKL----------------------------------
>NC_013947.1|c4|3688878-3692159|+|YP_003512242.1|Lanthionine_synthetase_C_family_protein
------------------------------MKPEAGVADVPASGFASLATERTTVNFVSD
PRTAALHLAEPLADRLASTPL-------------------------TDGSEATARLERWR
D--------------------REPFDNERHWRDRLAADGLDEDLLARLLG----------
---------ETSADLERRLPRPWWTGWLTEAA-----------TEPQVAPEEAPSTEGEP
FLAPVADDLVGPA---VRRLRADL---------ERLCERAARFDPAALVEQLRTGLA-WR
LHAMLGRTMTLE--LH-------LARNRGE-----L----TAAEP--AER--FAQFLTL-
ARDPAWRRGLFFRYPVLARQLTIGVEQWYANNLRLAERIAADTEVLSRRF----A-----
---------DGADLGKVTSISADAG--DQHRGGQTVAIVTWD---SG-------LRLVYK
PRSMRLDQTFSALVDWLND----------AGLTHPL-RTVECLDRGDYGWSEFLV--AEP
CRDAA-GVRRFYHRQGALLALLGLLRTNDMHAENL-MALDEQPVLVDLETLFQPRL----
-PDTNEQLTGAEQLAQQATAASVLQVGLLPAPAWVTREGR----AVDISGLGHLPG-QQT
SMPVPTLSGI-GTDDMR-VKLERVAMDLP----DHRP-V-AADIPLN-----LLDYADDL
LAGYTEMH-RL--CRTRRADLLAEDGPLAAFGG-MRVRVLLQSTVTYSTLFRTGFHPDVL
RD---ALDRER-HFDFLW-----RRIERTPALTAAI-AAERRDLWRNDVPYFEADTDGPV
VYD---SEGA--AVEG---LTVIGGLDLTRDAL-RDWDEEHLREQLAQIRGSL-------
--AAAAINTVARFEYPVYSSPEVAEPAAPEE--FVRAADRIGVHLRSRAFV--------A
GDSAQWLGL------SSHMGRNWSLGP--LTPDLFNGVAGVALFLAELSRATGDSS-YAV
-------LA--RQAT----------VTIRRQVERD--------PHILHGM--AGLPGIA-
YTF----CRLADL-------LGDESLRD-DAVGLAE----RTRAHDSPDAEF--------
--DIVGGAAGTIAALRVL----HDQRP----ESPAAEVIRAAADRL--------------
---------LDAAEAQDAGIAWLPAMMRENNLASRPPSGFGHGTGGIAWALAQAGGVLGE
----D-----RYAR----AAQDAITYERS-LFRPGDGTWQ----------DVRDPDGKAM
TCAW-CHGAVGIGLSRV---GMRDLVP--------GDRA-----AIDEEITV-----ALD
TARRDGF-------G-ISH----SLCHGDMGAVELF-LSAAS---LHDGP--ELRDETIR
RATSVLRTVETEG---------WICGLPF-----GEPTPSLM--VGLAGIG-YGLLR---
LNDPTR----VPSVLTMAVPTPPQRIQR-------------------------------
>NZ_GG753627.1|c1|45121-46839|-|ZP_06711240.1|lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
----------------------MAPAPSPRQADQAPHRDRQRSACSNRAG----------
---------PPPSGGLSASGTGAIPGSRGTRT-------------PAEFFEARPSPPRPA
TRSGRSGPLPEHGRLRRRARAVSPSWPGRRLRARLTPAIDRSAELDGILREFTATTA-AA
LGGLAARALVLE--LQ-------VARVEGR-----L----AGATP--QAR--FRDFVAD-
AGTGAGLVRLFTEYPVLARLAGRSCVNAVAAMAELLDRYAEDRAELVARL----L-----
---------AGRDPGPLVAVDRTAG--DAHRRGRRVAVLRFA---DG-------SRVVYK
PRPLAADRHFGELVDWYST-----------RAGTPVLRTPALLTRPGHGWSELIE--ARP
CASPA-ELDRFYRRLGALLALAHVLDLTDLHHENL-IACAGHPVLVDLETLFHPPL----
-----PEDPAADDPAGRALDASVQRIGLLPQLVLGDEG------ALDLSGLGGGAE-RRS
PVETAGWGGR--------------------------------------------------
----------------------------------GHRRHAAGPPARH-------------
-----GPRRDQ-------------------------------------------------
------------PPPA--------------------------------------------
-----------------------GRRPGRTR-----------------------------
-------------------------RP-------HRGAGGRLP-----------------
-------------------------RGLPRTPGAP-----------------AGTGRPA-
-------EPFRRR-----------------------------------------------
--RGPGGDPGH-------------------------------------------------
-------------------------------------PGLRDGP-------RRSHPPRRA
----A-------------------------------------------------------
-----RVGRPGRPAA---------------------------------------------
-----------------------AARHGRGGRPGLAGVARSR------------------
--DRRVARRRRAG---------------------VHRPPRPH----------RPVER---
HRRPRPRRP-RPAKDWPG-----------------------------------------
>NC_009953.1|c1|390871-393861|-|YP_001535270.1|lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
-----------------MPAAGGEVETEPGFAARLADLGMPQDPRLGESP----------
------------AELAARIRRPAWAVLVEDVL----------AAARPLPSDARPAADWRE
AFARVLAPFVDAA---LTQIRRHD---------------GRHVDLDRVAATVGDTLG-PR
LVGIAARALVTE--LH-------RWRAEGR-----L----AGGDS--QAR--FHDFVRQ-
LTAPTGLGEVLARYPVLARLLAQDTATTADATVELLDRFGLDRDALIATL----L-----
---------GGTDPGPVTSVLTSRG--DRHAGGRSVAFVDFD---DG-------RRIVYK
PRDLAPHTQLTVILEYLST-----------ATPGLFPRTPRTLARTGYGWAEHIA--ALP
LFTWE-DADLFYRRQGALLALLHLVRAADVHYENL-VAHGDQPVLVDVETLFHPGL----
------TPGGSGDPAADALAASVHRTALLPLVFVGEQG------VADVSGLGGDP--SAS
PSTVVDWLDA-GTDRMR-LTRRAADMAAA----ANRP-V-LNGRLVE-----PHEHDRAI
VGGFRHAY-DT--FIAHRDALT---ALVRDCAD-LEVRVVVRATWMYQTLLDETTHPDVL
RD---AVDRDR-ALSVLY-----HGRTEQPLLAQLL-RPELAALWAGDIPMFTASVGTGR
IRT---TSGA--EMPE---LLPQPGLAAALATL-ASLDEVSRRGQEWIISATL-------
---ASRARVAPHPDAAPIAAQPEGAAAHPDE--LLAAACAVADQLVAEANA--------G
GGRVNWLGL---EA---VEDHRWLVLP--LGASLGSGYLGVALFLAQLAAVTGIHR-YAE
-------QA--RAAT----ADLP--QLVAALDKRP----DLVAVIGCGGL--DGLGGIA-
YGL----ARIGTL-------LDDSALTD-AAARTVP----LAMAAATPGASL--------
--GWSAGLAGCLAALTAV----HTELK----LPEAADAARRCADLL------VAPLTESD
GVPGLMYRTHHGVSTDRAGGAWPAS------------GGFADGLAGVGWALTTIGPDDHH
----------HAAG----RRLATLLGDRG----------------------------EQV
AAGW-CRGTAGAVLART---ALSAATG---------PRS------LAGCVET-----LAN
APVRRDL----------------SLCHGELGVTEVL-AQLAG-----SDRRTLAAQALRR
RAGLVLDVLRRHG---------SLCGVPG-----GARSPGLL--TGLAGIG-YGLLR---
HAAPQR----VPSVLLLQHTMLAP-----------------------------------
>NC_013729.1|c10|6992599-6995490|+|YP_003384323.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MLDSATAATAHPTAWWSAGLA----------
-------------PHESGAQRPAWAEYIERST-------------ATTHEPEAATGDWQH
DLLRCLAPLLATA---RNDLLAAG-------------------HTGPVTDQFLQRLG-HR
LLKLSARTLVLE--LH-------RARVRGD-----L----TGATP--NER--FLDFTHR-
LAGGSELADLLAEYPVLARILGEACRQSVAAHHELLTRLAEDRELLVTTL----F-----
---------HGRDPGELAGVDPG-G--DPHRGGRCTTVLTFA---DG-------RKVVYK
PRPLDLHEHFNQIVDWLNS-----------RTAAAL-RTVRIVRRPGYGWMEFIE--HAP
CDDLA-AVRRFYHRQGALLALLYVLDGTDMHHENL-IAGGDQPVLVDVETLFHPAM----
----ASTGPLGQDPAHTALLSSVSRTALLPLMVVGEHG------AADLSGIGGDD--GVA
PHEVVDWADA-GLDSMH-LVRRAGKNQYR----DNRP-T-LRGSVTE-----PRDHEVSL
LAGFRSAY-EA--IARHRAELLGPAGLLTRCSA-DEIRYVPRPSRIYATLLDESTHPTAL
HD---ADGHSS-LLDLLW--------DANQELRQVV-PSELADLWSGNIPLFTTRPQTRD
VWA---SDGT--RVPG---LLRTEGLAAVEAKV-AAMGEVDQDRQCWVISASL-------
----ATRPAPVLHSSTATRPGLGTAEADPEQ--LLAAATDIADEVMAQVLG-------DN
GSQANWLGL---EL---LDDHHWTILP--MGAGLTNGYLGTALFLAQTGVLTGATK-YCE
-------LA--YDAI----RPIP--QVLEVLAASP----DAGQTVGAGL---HGLGGIS-
YGL----SRLAEL-------LDDSSLLS-----WLD----LSLQLMENAASRSEGVP---
--SYVEGAAGGLTAVQAI---------GS--GPRTTKLAAQYADEL--------------
--------LAAVNLHLQQAEP----------------AGFARGYAGIAWAL-GHYAAADS
----------QYHH----AARVAVERAEQ---------------------------TTAA
NPGW-CSGQAGTLLAGL---RAGGPVD------------------LDAYLRH-----ATE
RPMLADL----------------SLCHGELGAVEPL-LWLTE----RDHP--AVAAVRRR
RAGLVLAAVQQHG---------PQCGTPR-----AVPSPGLL--TGLAGIG-YGLLR---
LGFHGQ----IPSVLLQEPARPAPITAPAGHQPTGETS---------------------
>NZ_DS999641.1|c10|6903392-6905152|-|ZP_06580578.1|lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MFSPGA----
------------------------------------------------------------
---------------------------------HNRP-L-PAGRFLE-----GADNRAAL
LEGFRAAY-AA--LAADGHELLGEEGPLVSGAD-RPARLIARATRLYAALLEESTHPSLL
GD---ALAREG-VFAVLW-----TESEHDEARRRLI-EHETAALWRGDVPLFTHRPSGTA
VRA---DDGT--WLPG---VLPVAGLTSVRGKI-ARMDEVDCHDQEWIITATI-------
---AARGAGSPLRRPRSELAVGPVPAVAPDASRLLAAACGIADELAARAVR--------D
GGRTNWLGL------ERVSGPHWAVLP--MGAGLAQGYCGVALFLAHTDALAGAGR-YAA
-------LA--REAV----RPLP--ALLKALADDP----ELSAAAGPGAY--DGLGGIV-
YAV----LRLSAL--------LGPGPAD-CLPDALT----ALGHAASASPEP--------
--GFAGGTAGALTAAAAV----HEATG----APAALRLADVLADRL--------------
---------LGAVTGADGSVPSGAGGSGRPNGLP---AGFADGAAGIAWALLRYAARRPR
----D-----TAAH----TAAARALLDTA----------------------LRDAGAAPA
DASW-SRGLAGAAAVAA---HFSPAPG---------PPG------------------VAV
RPADTGV--------RPDL----SLGQGTLGTLEALAVHA-----GLGDR--AATDALTR
RAGQALALVEAQS---------HRCATPD-----HVPSPGLL--DGLSGIG-YGLLR---
LAHPGT----VPSVLLLSHPDH-------------------------------------
>NC_013131.1|c9|4203864-4206902|+|YP_003114474.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MSVAETWRYPQNPAHLEWAAFAARVL----------AGAAGDGAEPGDDRAGVR
GLIPVVEPFARAA----AEVARWEIGREVGHSIEPGSGGGSELDVDAVAAGFREALA-VR
LARLAARTLVLE--LN-------TARVSGR-----L----GAADA--ERR--FAEFVRA-
ASGRAGLAMLQRRYPVLIRLLAQTCLGRAAALAELVRRFRADRPELVRVL----L-----
---------HGVDPGPLLAVDGFAG--DGHRGGRAVAVLRFA---DA--------ALVYK
PRPVGVHRVFNEVAQWCNS----------RLAPWDL-RTLGVVERAGYGWTEFVA----P
EGTDPDGLDRFYHRHGVLLALLYVLDGTDIHFENV-IAHRDHPVLVDVETLFHPRF----
--------GRSPDPAAAALAESVYRTMLLPRMVVGDDS------VLDISGLGGERA-GRW
PLAAPDWAGA-GTDRMR-LVRRPPGFAGA----ANRPSLAGTKADATKTEAEPGRYAEAV
VEGFGAAY-DL--IQGSQSAWIGPGGLLGRFAE-HEVRVLIRDTAAYAVLLDESTHPDLM
RE---EERYHR-TFRELREQLGLTVALGEPADDDLA-DDELAELLAGDIPVFTARPGSAD
LWS---GPGR--RRPD---ALAETGLAAAERRV-RALSRADRDRQEWIIRSAL-------
----AARSPDPPHRFRAGPPAAPPSAAGPKH--LLTAARDIGDRLLAQACRAAADERAAS
EERINWLGL---EL---LADRFPHFGP--LGASLGTGYCGVALFLAQLAAVTGDAD-YAR
-------AA--RQAV----RPLP--GLLARLADRP----DRLAAIGSGAW--AGLGGIS-
YGL----AHIGAL-------ISELEFAE-AAILATD----LAARAAADETEH--------
--GVHGGTAGGLAALLAV----HQTTG----SAQAWDAATACADRL--VTSQVMADQAGA
GADHIAPDHPDPAAAASAHATRHQPHHHPEPSDPTPPTGFSHGPAGIGWALTRFADAGGG
----S-----RYAE----AGLTALRRAVA-----------------------QHTDAPGT
DPSW-CRGLAGVALAVA---DCPRAQT---------DPD------LSGFLAA-----AVH
RVRELPA--------PADP----GLCHGGSGVLELL-AAMGE--------------SVDG
YAGRLLAAAEASD------------GAPA-------ASPGLL--SGLSGLG-HGLLR---
AGFGKL----VAPVLLLRLPGG-------------------------------------
>NZ_DS999645.1|c1|66785-69889|-|ZP_06589146.1|lanthionine_synthetase_C_family_protein
-----------------------------------------MCPHPPRGTMGHAAGRQGP
RRDRGGGTLERNASGPGCGAAHPA------------------------------------
---------------------PGPVPAGRGAVALLENGQRHTGDAAWWLP----------
----------ALRPGERTGQAPDWAVWVERVL----------ATTPAVLAAPEGRYEGLS
GFERVLAPFAEAA---GERMAAAL-----------GGAERRLVDLTAVRAGLVRTVG-PR
LARIAARVLVTE--LH-------RAREAGG-----L----AGDDS--RAR--FRDFLRR-
TGERQGLTALLTAHPVLARLLGRVSLDAADAFAELLHRLAADQAALAEAG----------
-------LPCGADGHLLVDVEAGAG--DSHGGGRTVALLRFA---DG-------ARLVYK
PRPVAVHRHFNDLADWLGR----------LPGAPRL-RTLTVVDSQTHGWVEFVE--VLP
CRTGP-QVREFYRRQGALLALLHALDGTDLHHENL-IAHGEHPLLVDVETLFHPAL----
------PIADSDDPASRALHDSVHRVGLLPQFLLGDDS------ALDMSAVGGGRA-ALS
PVALAGWADC-GTDTMR-LVRRPGRFRES----ANRPR--LHGRPAE-----PAAYTAEL
REGFRAAY-AA--LGEARAELLGPTGLLERFRR-DEVRVVARPTAVYATLLDETTHPELM
RE---AGARDA-VLARLR-----DGTLGRPALSGLE-DEEIAQLWSHDVPVFTVPAGGTA
LTG---VTGR--AVPG---TVPLSGLARATRKI-AALDSVDRQDQEWVIRAAM-------
---VSASTAPVHHPAGAGRGPRPAAAPEPER--LLAAARSLGDQLVSLAYR--------T
ADRANWLGL------ELLGDRYWRLGP--MPADLAAGYCGPALFLAQLAGVTGVAR-YAE
-------TA--SAAL----APVA--GLLDALHEDP----TAPPAVGSGAF--AGLGGIT-
YTL----LETERL-------LGEPVCAE-SLPAALR----LLEAAAAGERET--------
--GVGAGTAGGLAVLLAA----HRATG----RQETLRAAGRCAERL--------------
---------LAAGPPAG--------------------TGFLDGSAGTGWALLRYAERTGS
----P-----RIRE----AGLEALRAAVA----------------------LLPAAKDEA
QGGW-CHGRAGTALAVA---DSPAALA---------DPR------LAAWLTT-----TAH
LLRRTEP--------RPDD----SLCHGEAGRLELLGHAALA----------GARAGLVH
RTGVLLAAVEDDG---------PRCGTPD-----HVPHAGLL--TGLAGIG-HGLLR---
AGFPDR----VPSVLLLDQPTRLITPDHRL-----------------------------
>NZ_ABYC01000011.1|c1|1722-4565|-|ZP_04700356.1|putative_lantibiotic_modifying_enzyme
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MWVERVLATT-------------PAVLAAPEGRYEGLS
GFERVLAPFAEAA---GERMAAAL-----------GGAERRLVDLTAVRAGLVRTVG-PR
LARIAARVLVTE--LH-------RAREAGG-----L----AGDDS--RAR--FRDFLRR-
TGERQGLTALLTAHPVLARLLGRVSLDAADAFAELLHRLAADQAALAEAG----L-----
--------PCGADGHLLVDVEAGAG--DSHGGGRTVALLRFA---DG-------ARLVYK
PRPVAVHRHFNDLADWLGR----------LPGAPRL-RTLTVVDSQTHGWVEFVE--VLP
CRTGP-QVREFYRRQGALLALLHALDGTDLHHENL-IAHGEHPLLVDVETLFHPAL----
------PIADSDDPASRALHDSVHRVGLLPQFLLGDDS------ALDMSAVGGGRA-ALS
PVALAGWADC-GTDTMR-LVRRPGRFRES----ANRP-R-LHGRPAE-----PAAYTAEL
REGFRAAY-AA--LGEARAELLGPTGLLERFRR-DEVRVVARPTAVYATLLDETTHPELM
RE---AGARDA-VLARLR-----DGTLGRPALSGLE-DEEIAQLWSHDVPVFTVPAGGTA
LTG---VTGR--AVPG---TVPLSGLARATRKI-AALDSVDRQDQEWVIRAAM-------
--VSASTAPVHHPAGAGRGPRP-AAAPEPER--LLAAARSLGDQLVSLAYR--------T
ADRANWLGL---EL---LGDRYWRLGP--MPADLAAGYCGPALFLAQLAGVTGVAR-YAE
-------TA--SAAL----APVA--GLLDALHEDP----TAPPAVGSGAF--AGLGGIT-
YTL----LETERL-------LGEPVCAE-SLPAALR----LLEAAAAGERET--------
--GVGAGTAGGLAVLLAA----HRATG----RQETLRAAGRCAERL--------------
---------LAAGPPAG--------------------TGFLDGSAGTGWALLRYAERTGS
----P-----RIRE----AGLEALRAAVA----------------------LLPAAKDEA
QGGW-CHGRAGTALAVA---DSPAALA---------DPR------LAAWLTT-----TAH
LLRRTEP--------RPDD----SLCHGEAGRLELLGHAALA----------GARAGLVH
RTGVLLAAVEDDG---------PRCGTPD-----HVPHAGLL--TGLAGIG-HGLLR---
AGFPDR----VPSVLLLDQPTRLITPDHRL-----------------------------
>NZ_ADFD01000018.1|c1|111348-114485|+|ZP_06274997.1|Lanthionine_synthetase_C_family_protein
------------------------------------------------------MAETDA
IDGTTPPGVPRASAAPGGTA----------------------------------------
---------------------VGPALGAPAHEHPGTLPAYGPDAGAETHDRALGTASLLA
ARERGGPWWLPGVVGQPPVREPDWAVFVREAV-------AAAPAAPADVPVADRDYPGLT
GFELVVAPFADRA---AERVAHAP------------SGRGAGPCPAAVLDGFRQDVA-GR
LARLAARTLVLE--LH-------EARTGGR-----L----AGDGT--RER--FRDFLRL-
AGSRSRLGSLATRYPVLARVLAQTALDAADAFAEMLGRLAADREPLASSGVLGSG-----
------GTPGGCGPEALTGVVPGAG--DSHRGGRSVMLLRFA---DG-------TRLVYK
PRPLAAHRHYTTLVDWFNS----------LAGSPDL-LTPRVLDRGAYGWAEFVE--DGP
CRSVE-ETALFYRRLGALLALLHVLDGTDLHHENL-IARGPHPVLVDVETLFHPPL----
------APTGFTDPAARALHASVHRVGLLPQLLVGDTS------ALDVSAVGGGRA-ASS
PVEGAGWAAA-GTDTMH-LVRTAGRFTES----ANRP-R-LDGVRTD-----PSAFTDAL
CEGFRAAY-TA--VSDARDELLGENGLLRLFSR-DEVRFVPRPTWAYATLLHESTHPDLM
RD---ATERQR-VFALLR-----TGALGPSALPGLE-DEEIAELWRGDVPVFTTRPDTTD
LWS---GTGR--AVPG---PAGATGLERVEAKV-RALDTVDRQDQERIIRTAM-------
---ASTSTEPPHRAVTGGRARVAAAAPEPER--LLSAARSVGDQLVSLAYH--------D
AGRTNWIGL---EL---LGERYWRLTP--MAADLACGYTGPALFLAQLASLTGESR-YAD
-------TA--RAAL----SPVP--GLLDALHQRV----DDLGPLGSGAF--AGLGGIA-
YAL----AEAGTL-------LDDPQVLD-WAGPATR----LSCAASSAEDGY--------
--GVRGGAAGGLVSLLAV----HRTTG----RAEAWRGAERCAERI--------------
---------AAAPLPAA--------------------GGFADGAAGIGWALLRYAGAGGG
----P-----RYRE----AGLSALRRAVR---------------------------GAHE
GQAW-CEGTTGIALALA---DSPDALA---------DPE------LSGWLAG-----RTG
ELAETGP--------LADD----SLCHGELGVLELLGHGALP----------QARPHWLR
RTGTLLAAADRAQ---------PHCGTPG-----HVPHPGLL--TGLSGIG-HGLLR---
AGFPDR----IGSALLMRHSPGADHRTPELSTTDQ------------------------
>NZ_ADFC01000059.1|c1|20476-23814|+|ZP_06282880.1|Lanthionine_synthetase_C_family_protein
----------------------------------------------MTEKDLIDRGPSRR
PAAAVPFASAPVAPGASAPAVSAESAP-------------------AVPVGSSPAVSVES
APVVPVGSAPAVSTGSTPAAPVGSGPVVSGASAPVVPVGSAPAVPVGSSPTAPVASVAAL
FSTLGEPWWLPGVVGGGPSGEPGWAVFAREAV----------ASAPRDVEVADRAYPGLS
GFGPIVAPFVEAS---ARRLQDAP-------AVGGSAAEGPTGDGSALLADFRRQLT-RR
LSRIAARTLVTE--LH-------EARRLGR-----L----SGEGA--KER--FRDFVRR-
TARRDGLALLVTGYPVLARLLATACLNAGDAFAEMAARLAADRHLLAPS-----GVLGDR
AGSPEGGRGGSTGPGALTGVEAGAG--DSHRGGRSVMLLRFA---DG-------TRLVYK
PRPLAAHRHFNALAEWFGS----------LSGAPEL-RVLRVLDRGEYGWAEYVE--ERP
CATAA-ETRLFYRRQGALLALLHTLDGTDLHHENL-IACGPHPVLVDVETLFHPPL----
------GPARSSDPAARALHDSVHRVGLLPQLLVGDTT------ALDMSAIGGGRA-ASS
PIETADWADA-GTDRMR-LVRRAGLFTES----ANRPR--MGGVAAD-----PSAFTEAL
CGGFRAGY-TA--ISEHRDELLGSDGLLRLFAR-DEVRVVPRPTWTYTTLLDESTHPDLM
RD---AAERHQ-VLSLLR-----TPLLGVPALPGVE-DEEVAELWCGDVPVFGTRPGSTE
LWS---GTGRTVPGQPDGETAGPTGLARVEAKV-RAMDTVDRQDQERIIRAAM-------
---VSTSPEPPHRSAPGGRSRSAATAPEPEQ--LLSAARSVGDQLVSLAYR--------H
ERRTNWIGL------ELLGERYWRLTP--MAADLAGGYTGPALFLAQLAALTGASR-YAE
-------AA--REAL----TPIP--GLLDTLHGRA----DELGALGSGAF--AGLGGIA-
YAL----TEVGTL-------LGDREVLD-QAGPAVR----LSCAASAAEDGY--------
--GVRGGAAGGLVSLLAV----HRATG----RPEAWRGAERCAERI--------------
---------AAAPLPDA--------------------AGFADGAAGIGWALLRFAGAGGD
----A-----RHRS----TGLAALRRATAGANRATAVGTA-----------PEPAARAAT
GPAW-CDGVAGIALAIA---DSPDALV---------DPE------LSGWLAA-----RSA
ELAGIGP--------LADD----SLCHGESGLLELLGHRALP----------AARPAWMR
RAGTLLASADRAG---------PQCGTPG-----RVPHPGLL--TGLSGIG-HGLLR---
AGFPDR----IGSALLLRPSGAP------------------------------------
>NC_010572.1|c18|5655167-5658604|-|YP_001826321.1|putative_lantibiotic_modifying_enzyme
--------------------------------MGATPPCAPTRSPATMDAGGPTGAGPGP
GRCGAVTEKDLIDRGPSRRPAAAVPFASAPVTPGASAPAVSAESAAAVPVGSSPAVSVES
APVVPVGSAPAVSTGSTPAAPVGSGPVVSGASAPVVPVGSAPAVPLGSSPTAPVASVAAL
FSTVGEPWWLPGVVGGGPSGEPGWAVFAREAV----------ASAPRDVEVADRAYPGLS
GFGPIVAPFVEAS---ARRLQDAP-------AVGGSAADGPTGDGSALLADFRRQLT-RR
LSRIAARTLVTE--LH-------EARRLGR-----L----SGEGA--KER--FRDFVRR-
TARRDGLALLVTGYPVLARLLATACLNAGDAFAEMAARLAADRHLLAPSG----V-LGDR
AGSPEGGRGGSTGPGALTGVEAGAG--DSHRGGRSVMLLRFA---DG-------TRLVYK
PRPLAAHRHFNALAEWFGS----------LSGAPEL-RVLRVLDRGEYGWAEYVE--ERP
CATAA-ETRLFYRRQGALLALLHTLDGTDLHHENL-IACGPHPVLVDVETLFHPPL----
------GPARSSDPAARALHDSVHRVGLLPQLLVGDTT------ALDMSAIGGGRA-ASS
PIETADWADA-GTDRMR-LVRRAGLFTES----ANRP-R-MGGVAAD-----PSAFTEAL
CGGFRAGY-TA--ISEHRDELLGSDGLLRLFAR-DEVRVVPRPTWTYTTLLDESTHPDLM
RD---AAERHQ-VLSLLR-----TPLLGVPALPGVE-DEEVAELWCGDVPVFGTRPGSTE
LWS---GTGRTVPGQPDGETAGPTGLARVEAKV-RAMDTVDRQDQERIIRAAM-------
---VSTSPEPPHRSAPGGRSRSAATAPEPEQ--LLSAARSVGDQLVSLAYR--------H
ERRTNWIGL---EL---LGERYWRLTP--MAADLAGGYTGPALFLAQLAALTGASR-YAE
-------AA--REAL----TPVP--GLLDTLHGRA----DELGALGSGAF--AGLGGIA-
YAL----TEVGTL-------LGDREVLD-QAGPAVR----LSCAASAAEDGY--------
--GVRGGAAGGLVSLLAV----HRATG----RPEAWRGAERCAERI--------------
--------AAAPLPDA---------------------AGFADGAAGIGWALLRFAGAGGD
----A-----SHRS----TGLAALRRATAGANRATAIGTA-----------PEPAARAAT
GSAW-CDGAAGIALAIA---DSPDALV---------DPE------LSGWLAA-----RSA
ELAGIGP--------LADD----SLCHGESGLLELLGHRALP----------AARPAWMR
RAGTLLASADRAG---------PQCGTPG-----RVPHPGLL--TGLSGIG-HGLLR---
AGFPDR----IGSALLLRPSGAP------------------------------------
>NC_012489.1|c5|4585042-4588533|-|YP_002763400.1|hypothetical_protein
---------------------------------MACHHGAETRLRISVSPSTNPTMLTDD
AFRRALTLRERAAAIRWHARPMLHQPGLQRDVPAHTSTPAATIAPTAALTPTQRRTARWQ
D--------------------QCSAGNAKRFAQRLGTEQLSIHDLPLLLD----------
------SEALPADRFTPAGTSAWWSDAAEPIPAAAPAAAPAAAPAAAPAAVPAPDNTSAP
NTSGSRQAFLGFLLLAAPQLRGAQ-ARLLHALRVLPGLRPLCRSPEHLAELACSALA-SD
IAECVSKVLILE--VN-------VMRLRGE-----L----VGETS--DER--FQHFIRT-
LDSDAARSAIFNEYPVLLRTIEQRVDHWYRHSLEVLQRLSSDRHAIEARL----L-----
---------NGATLGVLTEITYGAG--DKHHQGRCVTILGFD---SG-------RHIVYK
PRSLAVDLAFQQLVGWAAT-----------GMGDHAWRQPTHLPCGAYGWSEFVA--HQP
CADTE-GIHTFYRRLGAQLALLFALDATDMHLENV-MAQGDTPVLVDLEALFHPRF--DD
VVYDGDTATMQPDGGWSAYHDSVMRVGLLPSWSYHNTDGE----AIELSGIGGVAD-QLL
PEEQPTFSAI-GQDTMC-IVRQRARLPQA----KNQP-Y-LAGQRID-----PAAYADAI
VHGFRAAY-LH--LVEHGDELLGNEGLLEAFRQ-VDVRTVFRHTKVYGTLLRDSHHPDLL
RD---AIDRDI-HFDALW---RTVETRPWL--DRLI-PHELTDLQLGDIPHFTTRPASTS
VWA---SDGT--EIPG---FFARDAFGRAQERL-QSLSRADCDRQCWFIQAAL------A
ALATDPHGTPSPVADGGGKEKPSTTLNIQEY--ARYYVRWIADRLIHLAVQ--------R
DDDANWLGV---SL---VNEKHWSLQP--LGDDLYNGRLGVALFLLECDRLLGHPE-ARA
-------LA--SKTLESCARRMQ--WRVDQRPALS----EQPRSFGGSAF--HGHAGEA-
FVL----AHAARV-------WHEPRYAA-LAESLIE----YAGQDIARDDQL--------
--DVIAGVAGYLLVSSTL---------LDESVGISPAVRERIAEHMQQAGQQ--------
--------LLRNAERREDGWAWTTPIDASHPL-----TGFSHGASGIALALHRAGRRLGR
----A-----DLID----AAYQAVRYERH-AYEAANGRWP----DYRRIAIQPPEGGWPS
MHAW-CHGAPGIGLSRM-----ALLAD---------QPDVHAMQALHTDLER-----TVR
DTVRWGF-------T-GNH----SLCHGMLGNYALL-HDAAR---TTDGG--ITRDESDF
IATRVLESIDRAG---------VQCGIPR-----GTETPGLM--TGLAGVG-LGLLK---
MSGEQ-----VIDVLTLTLPERGTA----------------------------------
>FJ547091.1|c1|21837-24998|+|ACR33053.1|actagardine_modification_enzyme
--------------------------------------------------MSPVPSLNST
SVRDSAYLHERTVTGED-----------------------------QPAPAAQARIASWR
D---------------------SAFLDDRVLDIRLRQWGIDRATFGRLLT----------
-----------DDDFTVPGRLLAWADELATVL----ATDTTPVTGLELSTKLWSQGFDRL
LFAGLLHPFLAHY---EQRLHERV----------------PRPIAGSLRRPLLESLA-NR
LLAVAARTLLLE--LN-------VARVHGR-----L----TGDTP--QQR--YDDYDRRL
LTDPAYLAALFEEYPVLGRCLVECGRRWVDHAAELFNRLHDDEPELRAAG----L-----
---------LPPSAEALRSVRLDLG--DPHNGGRSVVQLTFD---DG-------TDLVYK
PRPVGSERAYAETMAALAR----------HGLPVPV-TAPRVLDRGGHGWCEFVR--PAP
CADAA-ELSRFYRRAGSVLAAMLLLGGVDMHMENV-IAAGSSFTPIDLETVLQSGE----
---LGDGATDAYGRALDLLNRSVLAIGILPARAFGGRQRK----SVDVSALGGGEP-QTA
PRPVPRIVDA-YTDTAR-LEAVEATMAGA----QNRPS--LPGAEVR-----PWEHTADV
VAGFTDAY-DI--MLAHRADFD---RLLRGFHD-VEVRYLPRPTRRYSIFLTESYHPDYL
RD---ASDRDR-LLDKLW-----TAADARPELIPII-ESEKRQLLAGDIPCFRSVAGSRQ
IRT---ASGP--LHPE---FFTAPAVTVLTRRL-GEFGPVHRAAQVRIIRDSM-------
---ATMPGPRPAAQPSPDRAAGPRPRVTGAD--PATLADRIARRLADEAIL--------G
DRDVSWIGV---SIEG-VAQETYSYKP--MATGLYDGVAGLALTFAYAARTLGDDR-YLD
-------LA--HRAA----RPVA--GYLRYLAEHR-------IVETVGAY--SGTAGLL-
YAL----DHVAHA-------TGDDSYLD-AVSEAVP----WLRECATREECP--------
--DLIAGLAGCALISLDL----HGRHR----IDGLREVAAICAERL--------------
---------AALAVDVDGAAGWPATPDGPLL------GGFSHGAAGIAWPLHRLATELGD
----P-----SLRE----LARRAVQFDRD-LYVPAAGAWR--------DLRPEMAGTDSY
PALW-CHGAAGIGLSRL---LIAQHDQ---------DTR------LAAEATA-----ALD
LVGAHGF-------G-HNH----SICHGDFGALALFDLAART---GFDPG------RHDA
AAAAVTADIAANG---------ARCGLVG-----DIHMPGLM--LGAAGIC-LSLLR---
IAHPAQ----VPAVAWLQPPLT-------------------------------------
>NC_009972.1|c6|2204861-2208103|-|YP_001544639.1|lanthionine_synthetase_C_family_protein
-----------------------------------------------------MTTHKQL
GWGATLPLAMRSMHVQQCCDQ-------------------------PLNAANQRRFDRWR
A--------------------QTPFQDSDWFSQRLAQNQLTPEQLQQFLQ----------
---------TPAQQFEADQAAPDWVALFEMAY--------RTPLSERLPYSAKLLQHPMH
GLLYLVEPLLAYA---VQHLQQQL---------SAVQPRQAFLQPAQWVTLWFEALA-QR
CLWMISRVTVLE--LH-------IARVQAQ-----L----NGTTP--EER--YQDFVQQ-
LQDRQRAQQLLQAYPVLIQQLCLTIQRWQTNSMTIFERLNHDWPALQQLF----P-----
---------VLQQTDGLIGIQTGAG--DVHAGGQSVVILSF----SN-------AKLVYK
PRSLAIDQAFQELLHWINQ----------HSSMLPL-RLLKILDRHDYGWSEWVD--HAM
LSDSA-AIERFYQRQGIYLALLYVLNASDFHHENI-IAAGEDPMFIDLESLCGPQV----
---HSDNQLENEFMANQVLTNSVLRVSLLPERFQARAGKT----GIDISGLGTRDG-QTS
MDTMPLWVEA-GTDSIR-MTKQTVSLSGS----QHSPIATVSAEQIG-------SYLNCV
VSGFEAMY-DF--LLAHRSELLADSSPLANLYR-CKIRVIARHTAYYTKIYQESFHPDVL
RD---ALDRDW-LFDRLW-----FEVKYNQRLVELI-PYEHRDLWQGDIPLFTTVVDSCD
LWS---SDGQ--RIAD---YLPRSGKTMVLERL-HQLSSNDLANQVRLISFSF-------
----ATMSASLHNSYRSDERYLLPTSIQPSHADWLLAACGVGDELLATALQ--------N
DHSITWIGL----------TQQLELQM--VGLDFYDGLPGIIYFLAYLGAISGVER-YTQ
-------AA--ERAL----QTLE--LLLEQHQATL---------TDVGAF--VGWGGLS-
YLY----WHLSSL-------WQQPALLE-KAKTWLA----QIPSLLANDSTF--------
--DLMAGAAGSLLVGLRL----YAQQP----SAELYTSLVACGEHL--------------
---------LANSQAEELGRSWQTITDAEQPAL----GGLAHGTAGIAWALIELAQLTND
----Q-----RYRE----SGLQALAYDNS-LFVADQQNWR-DIRTAKTKGNQQSDDLVIC
MAAW-CHGASGIGISRL---AMLRCLD---------DPT------INHDLQQ-----ALA
TTLTQGF-------G-MNH----SLCHGDFGNLALI-QAAAK---HYADQ--QLADQAQT
IASELFASIQRDG---------YRCGVQY-----GAQPPGLM--TGIAGIG-YGLLQ---
QAAPNV----VPLVTFLESPAIFPTNEPLLEVISRG-----------------------
>NZ_AAMD01000013.1|c1|28797-32015|-|ZP_01460524.1|MrsM_protein
----------------------------------------------------MHTLSPEL
SWRKAAFLHERAAPGRAAPPEEG-----------------------AALQHAQRRARAWR
Q---------------------VMSADERLLEERLRSAGLDREGFLQILA----------
----------HAEGGGDPSQHPSWEGLLQEVL----EDRAVNEPLPSFLAAPVSASGPGL
PFSGFLHPFLRLG---AARLRAGL------EALGARVPSPLPLVAPGIDALLLGGLA-AQ
LHELASRVLILE--LN-------VARLMDR-----L----QGSTP--QER--FHHFSTGV
LGAADTRAALLEEYPVLARLMATLLERWLETGLEFLAHLAEDRARLEETF----L-----
---------EGRALGPLVALQGGVS--DLHRGGRGVFLLQFG---SG-------LRLVYK
PKSLAVDRQFQQLLRGLNG----------AGLRHPH-RVLTVLDRGGHGWVEFVE--AGG
CDSRE-ALQRFYWRQGSFLAVLHLLSAVDFHLENL-IAAGEFPVGVDLEALFHHRP----
---PLGPSGKAYGRAWALLDQSIVAVGMLPISLFGRPGRA----GLDMSGLGGEAG-QLT
PQRMPTLEDS-GSDTMR-VVRRQGRMEGS----RNRP-R-LGAAPVD-----PTEFTEEL
IQGFEETH-AL--LIRQREALI---PQLRAFAG-VEVRYIARATQRYAMLLQESHHPDFL
RD---GLERDK-VLDHLW-----AEAVHVPLLRRLL-PFEHADLRLGDIPFFTARPGERH
LWS---STGE--CIPD---FFTQDSLGDVLRRL-DRMDAEDCALQVSFIRKAM-------
--VSLDKGRAPARALAAPAGEEPLPMATPEE--CLAAAVAIGERLAAKAIR--------G
DRDVSWIGL---NLED-LQQWRWSLSP--LGTELYEGLGGLALFFAHLAARTGRAD-FEA
-------LA--RAAL----EPVR--EDWRKLGQHG--------GTEVGVF--VGRGAAV-
YVL----GHLAAL-------WKEPFLRD-ELREGLP----ALEALIETDTRL--------
--DLLSGAAGLAVALLGL----YRTTG----EARWREAARRCGERL--------------
--------VATATPQPGGGVGWKGEVGMQPL------AGFSHGVAGIAWALLELAEATED
----P-----RYAD----LAHRGLAYERS-LFVPERGQWK---------DLRAPDTEGHF
MAMW-CHGASGIALGRL---LALRHLE---------GAE------VREELST-----ALE
TTLRTGF-------G-GNH----SLCHGDMGNLEVL-HLAGT---VLGER--QWTQAALR
CATAVLRQGREED---------WRCGLPR-----GSESPGLL--MGLSGIG-YGLLR---
LSAPGH----VPSILSLASPTGE------------------------------------
>NC_008095.1|c6|3327756-3331079|-|YP_631068.1|putative_lantibiotic_modification_protein
---------------------------------------MEITQRQDKAMPGANTPSRFA
RWARATPLTERVEFTLKANTTQQ-----------------------DTSGAARKRLDAWR
Q--------------------QEPFGQADWWQRRLQSSGLTEAELLTLLE----------
--------VPTEAPWTPPAEVPRWVQVLEHTY--------AEPSHAPVPWPERTEGPDRS
AFLPLVDPLVSRA---VTQLTAAL-------KPMKHAAPGLDLEPSVVVSTMLGHLP-QV
LAPVLGRAMVVE--LH-------AAQLEGL-----L----AGDTP--EAR--FQDFTRR-
LRQPQVALDILERYPVLARCVVLRIGEWESNCLGLMKRLTRDAPLLWQRF----N-----
---------AGQSPGALVEARGGFS--DPHRGGQGVFILRFE---SG-------LRIVYK
PRSLGAEAGLQQLLTWLNA-----------RGATPMMKGAEALDRGEYGWMEYVD--PAP
CASAE-EVRRFYERQGAYVALMHALDGTDLHFENL-IAAGEHPVLVDVETLFHPLS----
----GTRTLRDSEHAVEAPPVSVLRSGLLPQQFWGTRKKA----GVDLSGLGARAG-QLT
PQAYLMTTER-GTDRMR-FERRPVEMPGS----NNLP-R-LEGETAP-----VLDYRDAL
ADGFTRMY-GL--LLEHREALLAEDGPLAAFAH-VPMRVLFRNTAVYGALLFESYHPHAL
TD---GLERQR-FFDHLW-----RAVVPAPDFAALV-PLETEQLERGDLPYFTARADSKD
LEA---GSGQ--RLPD---FFQETGMARVRRRL-VGLSPEDQTRQRWVLERSL-------
---DVLLLSSQTVARPTYPFREHTQPGLRDA--LLVEARRAGERLLPLAFE--------R
RDEAHWLGL-------DAGDGGWRLGS--PGPDVFQGRAGIALALGYLADVTQDAR-FTR
-------LA--RATL----RTQA--RLLAEEPASV---------VGLGIL--NGWGGIL-
YAL----THLGVL-------WKDDALLD-EAAGYVR----RLRPLVEKDTVL--------
--DVGAGAAGCLLALLVL----GEHRP----SDTLWATVDACGQRL--------------
---------LETSTPQARGAAWLCEAAGNRYL-----AGMAHGAAGISLALLRLFARTGD
----T-----RLRD----AAVAGMEYERG-LYTPEERNWP-DLRAGAKELAAAAEGTEHF
LWAW-CTGAPGIGLARL---SGLPFVD---------DAE------VREEIAI-----ALD
STLARGF--------GRNH----GLCHGDLGNADFL-LEAAA---TLGDS--KLQERTNA
VAGGILRGISEHG---------YLFGLQG-----STETPGMM--VGLAGIA-YGLAR---
LAMPER----LPSLLTVAPPRIVRGEGLGTPDGRPSSRNQELS----------------
>NC_008095.1|c18|7869017-7872286|+|YP_634512.1|lanthionine_synthetase_C_family_protein
---------------------------------MEALSQTRRRTTRTPQAAAWIGEGVTS
HWVLGHALEERLPSLRMRGTPDA-----------------------VDEARARRRLERWR
K--------------------QEPLTRDSLWAERLRASGLTEAELHTLLG----------
--------EPAEALHARMGAPPPWQRVIEQAY----------ASEISPPFSWPEPTPPGA
ALLGLVEPLVHAA---HARLVSAL-------DTCLRDTPEAPFEPEHTARMLLAPLP-RM
LMPLLGRTLAVE--LR-------IAQLEGR-----L----QGDTP--EAR--FLDFAQH-
LRRRDVALDILARYPVLARQAVEYVTAWEATGVELMQRLARDAAALWHRF----H-----
---------GGVPPGLLVEAQGGLS--DPHRGGRTVFLLRFA---SG-------LRLVYK
PRPLTAEAVFQQLLSWLNA----------RGLTPPL-RTVEVLSSDGYGWMEYVE--AAP
CQSAE-EVRRFHLRQGALVALLYALDVTDIHYENL-IAVGEHPVLVDLETLFHPHT----
---LAASIRDVEKQPGAVLNGTVLKSGLLPQPAWRAKDGT----EVDFSALGAGEG-QLT
PLGYLVATAH-GTDQLR-FERRRMEIPGA----ANRP-R-MEGQDVS-----VTAQADAL
AQGFSALY-RL--LAEHRDALLAPGGPLAAFEH-APVRVLFRGTASYDALLHESMHPHAM
GD---ALDRQR-FFDHLW-----LAVKERPYLAALI-PFEHEELQRGDIPRFTALPGSKD
LWS---GAGR--HLPD---FFDDSGLERARRRL-TGLSPDDHERQLGLLRSAL-------
---GRVRLAASPGDRPRYPFREPPAPAHPDA--LLAAARRVGERLVALSFT--------G
AGHSHWLSL---EM---SDTKEWRLVQ--VGVDFYQGLSGIALVLAQLGALTGEAR-FTQ
-------AA--RGAL----RHLT--WRLEAAPMQV---------RGVGIL--NGWGGIL-
YAL----THLGAL-------WGERALFE-TAESFVD----AMAPRVEQDEHL--------
--DLGSGCAGALLGLLTL----VGRHP----SERASRLARVCGEKL--------------
---------LQTATPQSHGMGWLSPATGGQAL-----CGLAHGGAGIALALLQLASATGE
----S-----RFHT----TALEALAYERG-RFSPEAGDWP----DLRADAGVHGGDGPAF
MCGW-CNGAPGIGLARI---SGLPVLD---------DHQ------VREEIAA-----AVR
ATLAGGL-------G-YNH----GLCHGDLGNVLFL-LEAAR---ALHDD--TLLRRTYQ
LAGGILQGIESHG---------YLHGLPD-----SIETPGLM--VGLAGIA-HGLLR---
LAAPER----VADLLSVAPPVS-------------------------------------
>NZ_DS989847.1|c1|224829-228119|-|ZP_05025883.1|Lanthionine_synthetase_C-like_protein
---------------------------------------------------MHQTSFQSS
AWYNAIPLTERITFLRTQQSKTPKVE--------------------VNVALAQRRMQRWK
S--------------------QFPFTNDSYFDQRLTMDAITEKEFIYLLG----------
--------EPTDVMKTRFSAIPDWLTDLAQAF-----FHPTYSNATIILPPQKLGEQKES
GFLYAIEPLISQG---LDRLHEGI-------QKLIQTYQNLPFDPTTIKALLFANLP-GE
LLWMLNRTMILE--LN-------VARLQGL-----L----VGDLP--EDR--FQSFLER-
LHQHEVVIFILKEYPVLARQLVISINQWVSYSLEFLQHLCTDWSDIRTTF----S-----
---------PEAETGVMVQIDGGVS--DTHRGGRSVLIAKFS---SG-------FQIVYK
PKSLAVDVHFQQLLEWLNQ----------RGNYPPF-RTIKIINRGTYGWVEFVT--AKG
CNDPE-CLQNFYKRQGGYLALLYALEATDFHLENL-IAVGEHPVLVDLESLFHPRI----
---ESIDIKKSEQLAINTIDNSVLRVGLLPQRFWANAESE----GAEISGLGGKEG-QLT
PHRVSYSEEI-GTDEMR-VARKQMPMSGS----QNRPT--LNDAEVN-----VLDYTEAI
ITGFTNIY-QL--ILQYRDELLSENSPLARFAE-DEVRFLLRQTRSYGLLLHESFHPNLL
RN---ALDRDR-FFDRLW-----VGIEKQPYLTKVI-AAERDDLWQGDIPMFTTRPNSRA
IWS---SFNK--KIAD---FFDETGMTLVQRRI-QQLSNADLKQQIWFVRASL-------
---STLAMAEEQAKWPTYHLNKPQNSASYEQ--LVAAAQVVGDRLEKLALN--------G
EKDISWIGL-------TLIEKHWTLTA--LEIDLYEGLPGVILFLAYLGALTEQKR-YTA
-------LA--KAAL----VTMQ--RQVESSREYI---------KSLGGF--SGWGGVI-
YTL----TQLGVL-------WNEPELLT-EAESLVE----QFPNLISKDEQL--------
--DILSGTAGGLASLISL----YRCRP----SQRTLAAAIQCGERL--------------
---------ITTAKPMEYGVGWTTQIAELKPL-----TGFSHGVAGIAWVLLELASLTGE
----Q-----RFKT----TALAAIEYERS-LFRPEVGNWPDLRDFSSSILADKDDNQPTC
MTAW-CHGAPGIGLGRL---RSLPHLD---------DAK------IRTEIDT-----ALK
TTLEHGF--------GSNH----SLCHGDLGNLELL-LQASQ---TFDDP--QWKTQVDR
FAAIILESIDKYG---------WLCGVPL-----GVETPGLM--TGLAGIG-YGLLR---
LAAPDR----VPSVLVLEPPKLNRAVQKSTDCAIAI-----------------------
>NC_007410.1|c1|266582-269758|-|YP_320138.1|lanthionine_synthetase_C-like
---------------------------------------------------MKKFNYEDA
TWYRAVSLTERIAAMSLTAP--------------------------LNADLGQRRFQRWR
M--------------------QSPFMNEALFVQRLAIDGLKVDDFCYLLG----------
--------------QTAPQIPQAWLGKLTAVF---------SNPEDEEIIEIQGLPDPHL
GLLNAIAPCIRQG---MMQLRVGV-----------DNLQNIPIDISNIDSIFLQGLP-EQ
LLFMLHPTLVLE--LN-------VARLQGL-----L----TGDTA--EER--FSSFVQR-
LQTGEARLMLWQEYPVLARLIIEEIQRWVTTSLEFLQRLGDDWEEICHHF----Q-----
----------PNNPGKLIKIQRGAG--DSHHGGRSVFILEFE---SG-------WQLVYK
PRSLAVDEHFQELLLWLNQ----------QGTHPPF-KTLKILNRGDYGWMEFVK--AQK
CTSLE-EIQRFYQRQGGYLALLYVLSATDFHFENL-IAVGEHPILIDLESLFHPRS----
---HEATTTAAATLDREMIADSVLRVGLLPQLVWGNTQAA----GIDLSGLGGAAG-QVT
PERVPQLEKI-GTDTMR-IVRRQVVLAGS----QNRP-T-LNEKEVN-----VQAYTPAI
TQGFTDVY-RT--LLQHRQELL---KILERFVA-DEVRVVLRPSRSYALLLRESYHPDVL
RD---ALERDR-LFDKLW-----VDVQNRPLLTQVI-RAEHQALWQGDIPLFTTHPHSCD
LWS----RDTNLHLPN---FFTQSGMELVHHRI-QQLSERDLQRQQWFIQSAL-------
---ATLGINTNTDQHQVKHSASISNSQIPTPHSPLTAACIIADRLELLAHK--------N
GELINWMGV---TV---TNNHQWTLAP--LGTDFYEGVPGIAFFLAYLGEITQNYH-YTR
-------LA--KAAI----KTLQ--QQLIRDTDTI---------KFIGAF--SGWGGII-
YTY----THLGTL-------WQNPDLIA-DALTLVK----KLPGLIVQDEQL--------
--DMIAGVAGCIASLLSL----YQVFP----NDLILDVALECGEHL--------------
---------LNQAQIMDDGIGWISPSGGKQPL-----TGFAHGAAGFASVLLELAQITGK
----Q-----EFQT----AAIKAINYERR-HFSPEAGNWL----------DLRTPAQNQF
MTAW-CHGAPGIGLGRW---RALKYLD---------DPE------IHKEIAI-----AIH
TTINQGF-------G-DNQ----CLCHGDLGNLDLL-LLASK-----IQP--ELTSHTSP
ITNQILNQIHQHN---------FYCGVPL-----AIETPGLM--TGLAGIG-YGCLR---
LDHPEK----IPSILLLEPPHTNSKFKIQN-----------------------------
