>NC_010080.1|c1|642081-643292|+|YP_001577104.1|hydroxymethylglutaryl-CoA_reductase
------------MKFYQLKPEQRREILQSEGINLEDIDDQVL-------------NRLDK
LSENVVGQLRLPLGVVQNFLLNGQSYMVPMAVEEPSVVAAANHGAHIFARNG--GVKATS
KRTGIYGQIVLKVNHDF----SLPDLKKKFPD---LIDLANKEFASLIRHGGGTRSIEAE
R--------KGD----------------LVYLKVLVDPAEAMGANKTNSILEFLAAKLK-
QFPGIEEKLFAILSNYPS--QLTKATVTLDPKTM------------GGRKVAERVALLSK
IGYEDPYRAVTNNKGIMNGVDAVLIATGNDYRAIESATAVLASQDGHYRSLSKWTMQD--
GKLVGELTLPMAIGVVGGSIKARKDVQQSFAILGKEINSAKLAEIIVSVGLANNLAALLA
ISTVGIQAGHMKLQARNIVSELDASDEEKKKVLAQIIKQ--KDYSESYAQAVLKQIREGK
--------------------------------
>NC_010163.1|c1|214499-215728|-|YP_001620225.1|3-hydroxy-3-methylglutaryl-CoA_reductase
-------MNKLLKNFYKKSIEERIEALESIDRFDAS------------LNKSAGDIVFDH
LIENFITTYEVGLGVAPDFLIDDVLYHIPMATEEPSVIAGAAHAAKIIYRNG--GFKIDE
INRVMIGQIIFKNVSDPKA--LIDYLNSHKET---FKDIAYKAHPQIHNLGGGLLSFKVE
DK-------TQG----------------FVCFYASINTLDAMGANTINTILEAISHFVTI
DY-K-AEVLMSILSNLAV-DALVSASVKIDPKHL-----------KNSDVIHKDIAAAST
YAHIDPYRAATHNKGIMNGISALMLATGNDTRSIEAGAHAYASVSGKYIPLTKWYVKDDF
--LVGEIKIPLALGTVGGSMGILPKVKLSHKILGVK-NAMELMKVAACLGLAQNFAALYA
LTTDGINKGHMRLHARNVALEAGAQPSNINEVVNHLVTS--KEITVANAKEFIKTLS---
--------------------------------
>NZ_ACGF01000109.1|c1|56407-57732|-|ZP_03937088.1|hydroxymethylglutaryl-CoA_reductase
-----------MAAFRELSVEQRIKTLESEGTLSGDYTQLLLAQLAQSSETNIPASVANS
MIENQIGRFSLPVGVVRGLKVNGVMQNVLMATEEPSVIAAACNGAKIAAKSLENGVVAHS
AHYVTRAQIVFEDADGSVAK-KLDSIMRNESKRTAIREVARSAHPSIYQRGGGLERAQAA
A--------LTG----------------FAKLTLDINACDAMGANIANTIGEAVKTQLE-
SWVG-RKALVAILANSS--RAATVAEVRIPVEALVPSAKTAAAGDADGMRLARRIAALSS
LAAVDAERAATHNKGILNGIVAAALVSGNDTRALQAAAHEWAAKSGRYMPLSTWTLQNSG
QILYGRIEIPLQIGTVGGAIASLPMSKVALQVSKVN-NANDFRNVLAAVGLVQNLAALRA
LAGPGIQAGHMRLQAANIAIASGARGDEIQKVAHALLNENSSDLNTNSARMILDNLRKDK
NT------------------------------
>NZ_GG770319.1|c1|583916-585319|+|ZP_06751841.1|hydroxymethylglutaryl-CoA_reductase,
------------MKFHQMDPERRRETLVSEGVLTPEQAEELG------RTGGLDPDVARN
LIENVIGQYSLPLGVARNLTVNSKTYQVPMVTEEPSVVAAASNGARIANLNG--GVAASP
AQRLVTGEVVFCADSGPQAEEVKTILESHRED---VFSLAAAAHPSIVSYGGGLTDLWVD
LIPAQGPLGSSAPLKPLGPSRLSGFSGYFVKLSLLVNPCDAMGANIVNTISEAVANAAE-
AWTG-RPRLVAILTNNSPLAAAVTAHVELAPETF-----AT--KTMAGQKIAGRIALLSD
LAQSDPDRAVTHNKGIMNGISAAVLATGNDTRAVEAGAHAFAARTGTYLPLSQWSLNGQ-
GKLCGQLTLPLQVGLVGGATSSLPLAGLAKKMLACQ-STDEFQCLLAALGLVQNLAALRA
LAGPGIQEGHMALQARSLAMAAGAQGEEIEQVSDLLQKD---DKSLARAKVLLAGIRDQR
DQRERGERKNQNEYKDQREDKEQA--------
>NC_013198.1|c1|1868099-1869358|-|YP_003171584.1|hydroxymethylglutaryl-CoA_reductase
------------MKFYEQTPEARRQQLVQEGSLTSADAALLA------AVRTLPDATATR
LIENAIGEFSLPMGIARNLMVNGQQHQVPIVNEEPSVVAAASNGARMVAENG--GVLAHV
GTHEVVAEVVLTDLADLNA--ARQILLAHQAT---IAAVANASHPSMVQRGGGFSKMTVT
IL-------ANR----------------FLKLRLTLNPKEAMGANYANTVAEAVADAVT-
AWVD-GTVLASILTNAP--GELVTATVKLTPATL-----AT--KTLSGDEIAHKIVQLSD
LAFVDPERAVTHNKGILNGVIGAVLATGNDTRAVAASVGAFAAATGQYQPLSRWLMRD--
GKLEGHLQMPLPLGVVGGAIGALPLAQAARRLGGYR-DLATMQQVIAALGLVQNLAALRA
LAGPGIQSGHMKLQANALAIAAGAQDQEVPTLVAALRAG---EMDLAHAKMYLATIRSKQ
KAGH----------------------------
>NZ_ACIZ01000074.1|c1|8605-9849|-|ZP_04441361.1|possible_hydroxymethylglutaryl-CoA_reductase
------------MKFYEQTPEARRHQLVQEGSLTSTDAALLA------AARTLPDATATR
LIENAIGEFSLPMGIARNLMVNGQQHQVPIVNEEPSVVAAASNGARMVAENG--GVLAHV
GTHEVVAEVVLTDLADLNT--ARQILLAHQAT---IAAVANAAHPSMVQRGGGFRNLTVT
IL-------ANR----------------FLKLRLTLNPKAAMGANYANTVAEAVADAVT-
TWVD-GTVLASILTNAPS--ELVTATVKLTPATL-----AT--KTLSGDEIAHKIVQLSD
LAFVDPERAVTHNKGILNGVIGAVLATGNDTRAVAASVGAFAAATGQYQPLSRWLMRD--
GKLEGYLQMPLPLGAVGGAIGALPLAQAARRLGGYR-DLATMQQVIAALGLVQNLAALRA
LAGPGIQSGHMKLQANALAIAAGAQDQEVPALVAALRAG---EMDLAHAKMYLATIRSK-
--------------------------------
>NZ_ABWJ01000010.1|c1|26253-27512|+|ZP_03211417.1|Hydroxymethylglutaryl-CoA_reductase
------------MKFYEQTPEARRQQLVQEGSLTSTDATLLA------AARMLPDATATR
LIENAIGEFSLPMGIARNLMVNGQQHQVPIVNEEPSVVAAASNGARMVAENG--GVLAHV
STHEVVAEVVLTDVADLNA--ARQILLAHQAT---IAAVANAAHPSMVQRGGGFRNLTVT
IL-------ANR----------------FLKLRLTLNPKEAMGANYANTVAEAVADAVT-
TWVD-GTVLASILTNAP--GELVTATVKLAPATL-----AT--KTLPGDEIAHKIVQLSD
LAFVDPERAVTHNKGILNGVIGAVLATGNDTRAVAASVGAFAAATGQYQPLSRWLMRD--
GKLEGYLQMPLPLGAVGGAIGALPLAQAARRLGGYR-DLATMQQVIAALGLVQNLAALRA
LAGPGIQSGHMKLQANALAIAAGAQDQEVPALVAALRAG---EMDLAHAKMYLATIRLKQ
KAGH----------------------------
>NC_007576.1|c1|1460261-1461529|-|YP_396094.1|hydroxymethylglutaryl-CoA_reductase
---------MTSPKFYQLSKSERLARLVEANQLSEKDAQFLA------QSQPLADELADS
MIENYIGQYHLPLGIVQDVMVAGKVYQVPMAIEEPSVIAAANNAAKMMRLNG--GVTIES
GQRVMFGEVVLTDLPQLAD--AVKWVDNHFAI---LQTVAQKAHPSIVKRGGGLQKITTT
IV-------ENR----------------FLKLNLEIDTKAAMGANIVNTICEAIAHAVQ-
ATLG-GTILLSVLTNAAF-GSVVKASVTLNPETL-----AT--ATLTGDAVAQRLIDATQ
FAQLDVARAATHNKGIMNGIDAVIMATGNDWRAIEAGAHSYAARTGHYQPLTDWSWTSDH
Q-LRGQIAVPLPVGIVGGSIGILPTVQVAQRLMVIE-TAEELAGVIAAIGLGQNLAALKA
LVSDGIQKGHMALQAKSLAIAVGATASELTTLLPQLLKA--PHLNTETATTLLSQIRAEN
R-------------------------------
>NC_012121.1|c2|1886752-1888026|-|YP_002634974.1|putative_hydroxymethylglutaryl-CoA_reductase
-------MKALGKDFRHLSRKDKLQRLKENGWILDESRQELW------DYPLLSEEVADS
LIENVITQGALPVGLLPDIEVDGKHYAVPMMVEEPSVVAAASYGAKLVNKTG--GFHVES
SERLMIGQIVFMDVEQPNK--LAEQLLEKEAQ---IHQIADTAYPSILKRGGGYQKIDVD
TFS------EEQ----------------LVSLKVYIDTKDAMGANMMNTILEGISGFLKG
EWPD-INVLMSILSNHAT-ASVVRVSGEIDIANL-----AR--GDMDGAEIARRLEAASV
LAYVDPYRAVTHNKGVMNGIHAVVLATGNDTRSAEASAHAYACKEGQYRSMTKWEYLPSK
ARLRGTIEIPMTLATVGGGTKVVPIARLAQELLHVD-SAKELGEVAAAVGLAQNFSACRA
LVSEGIQEGHMSLQYKSLAIVAGAKGDEIEKVADALKTA--DTANMAKAKEIIADLRE--
--------------------------------
>NC_013893.1|c3|494299-495588|+|YP_003470723.1|Hydroxymethylglutaryl-CoA_reductase
-------MTSLSKDFRHLTRSQKLNQLETHGWITSETHDILL------NHPLIDEDIANS
LIENVIGQGTLPVGLLPKIIVDDKEYVVPMMVEEPSVVAAASYGAKLINRTG--GFKTII
SERLMIGQIVFDNVKDTAS--LATLIKQLESQ---IKAIADESYPSMIARGGGYRRLDID
TFP------QDG----------------FLSLKIFVDTKDAMGANMLNTILEGITNYLKH
EFPE-HDILMSILSNHAT-ASVVKVQGEIDVEDL-----NR--GDYRGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASVHAYASRAGQYRGVATWQYHRQR
QKLIGTIEVPMTLATVGGGTKVLPIAKASLELLNVG-SAQELGHVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIQQVANELKKT--DRANTTVATQILKQLRRND
ELK-----------------------------
>NC_007350.1|c1|357196-358479|+|YP_300416.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
-------MEALDKSFRHLSREDKLNTLVQKGWLNEENKNTLL------NNPLIPEEIANS
LIENVIGQGTLPVGLLPEIIVDDKSYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKVIS
SERLMIGQIVFDGVSDTEI--LSQQIYNLETQ---IKQIADEVYPSIIERGGGYRKIDID
TFP------NEG----------------LLSLKVSVDTKDAMGANMLNTILEGITAYLKN
ELKD-VDILMSILSNHAT-ASVVKVQGEITVDAL-----SK--GDRDGEAVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEATAHAYASKDGQYRGLATWKYDEER
QTLVGTIEVPMTLATVGGGTKVLPIAKASLDLMKVD-SAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAQGEEIAQIADMLKTQ--PRANTAVAQQLLDELRLQK
Q-------------------------------
>NZ_ACLP01000020.1|c1|24807-26084|-|ZP_04060294.1|hydroxymethylglutaryl-CoA_reductase,
-------MKSLDKNFRHLSREDKLKQLVDYGWLDKTNYQTLL------SNPVIDEEVANS
LIENVIGQGTLPVGLLPKIIVDEKEYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTIK
SERLMIGQIVFDDVKDTED--LTQRIQKQENQ---IKRIADEAYPSIIRRGGGYRGIDID
AFP------NEQ----------------LLSLKVFVDTKDAMGANMLNTILEAVTAYLKN
ELTD-QEILMSILSNHAT-SSVVRVEGEIDINDL-----NR--GDYSGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYAARDGQYRGMATWKYDKAR
GRLVGTIEVPMTLAIVGGGTKVLPIAKASLDLLNVE-SARELGHVVAAVGLAQNFSACRA
LVSEGIQKGHMSLQYKSLAIVVGAKGEEISKVAEQLKQE--PKANTEAAKRILKSIRQS-
--------------------------------
>NC_003923.1|c5|2626758-2628038|-|NP_647283.1|hydroxymethylglutaryl-CoA_reductase
-------MQNLDKNFRHLSRKEKLQQLVDKQWLSEEQFDILL------NHPLIDEEVANS
LIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTVS
SERIMIGQIVFDGVDDTEK--LSADIKALEKQ---IHKIADEAYPSIKARGGGYQRIAID
TFP------EQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAFLKN
EFPQ-SDILMSILSNHAT-ASVVKVQGEIDVKDL-----AR--GERTGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGIATWRYDQDR
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVE-SAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIAKVAEALKKE--PRANTQAAERILQDLRSQQ
--------------------------------
>NC_002758.2|c4|2687648-2688925|-|NP_373069.1|hydroxymethylglutaryl-CoA_reductase
-------MQSLDKNFRHLSRQQKLQQLVDKQWLSEDQFDILL------NHPLIDEEVANS
LIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTVS
SERIMIGQIVFDGVDDTEK--LSADIKALEKQ---IHKIADEAYPSIKARGGGYQRIAID
TFP------EQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAFLKN
ESPQ-SDILMSILSNHAT-ASVVKVQGEIDVKDL-----AR--GERTGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGIATWRYDQKR
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVD-SAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIAQVAEALKQE--PRANTQVAERILQEIRQQ-
--------------------------------
>NC_007622.1|c5|2553966-2555246|-|YP_417868.1|hydroxymethylglutaryl-CoA_reductase
-------MQSLDKNFRHLSRQQKLQQLVDKQWLSEEQFNILL------NHPLIDEEVANS
LIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTVS
SERIMIGQIVFDGVDDTEK--LSAEIKALENQ---IHKIADEAYPSIKARGGGYQRIAID
TFP------EQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAFLKN
EFPQ-SDILMSILSNHAT-ASVVKVQGEIDVKDL-----AR--GERTGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASKDGQYRGIATWRYDQER
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVD-SAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIAQVAEALKQE--PRANTQVAERILQDLRSQQ
--------------------------------
>NC_002952.2|c4|2709121-2710401|-|YP_041970.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
-------MQSLDKNFRHLSRQQKLQQLVDKQWLSEEQFNILL------NHPLIDEEVANS
LIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTVS
SERIMIGQIVFDGVDDTEK--LSADIKALEKQ---IHQIADEAYPSIKARGGGYQRIAID
TFP------EQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAFLKN
EFPQ-SDILMSILSNHAT-ASVVKVQGEIDVKDL-----AR--GERTGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASKDGQYRGIATWRYDQER
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVE-SAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIAQVAEALKQE--PRANTQVAERILQDLRSQQ
--------------------------------
>NZ_ACKI01000038.1|c1|58274-59554|+|ZP_05687792.1|hydroxymethylglutaryl-CoA_reductase,
-------MQSLDKNFRHLSRQQKLQQLVDKQWLSEEQFNILL------NHPLIDEEVANS
LIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTVS
SERIMIGQIVFDGVDDTEK--LSADIKALEKQ---IHKIADEAYPSIKARGGGYQRIAID
TFP------EQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAFLKN
EFPQ-SDILMSILSNHAT-ASVVKVQGEIDVKDL-----AR--GERTGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASKDGQYRGIATWRYDQER
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVD-TAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIAQVAEALKQE--PRANTQAAERILQDLRSQQ
--------------------------------
>NZ_GG730183.1|c1|180745-182025|-|ZP_06325646.1|hydroxymethylglutaryl-CoA_reductase
-------MQSLDKNFRHLSRQQKLQQLVDKQWLSEEQFNILL------NHPLIDEEVANS
LIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTG--GFKTVS
SERIMIGQIVFDGVDDTEK--LSADIKALEKQ---IHKIADEAYPSIKARGGGYQRIAID
TFP------EQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAFLKN
EFPQ-SDILMSILSNHAT-ASVVKVQGEIDVKDL-----AR--GERTGEEVAKRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGIATWRYDQER
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVD-SAQELGHVVAAVGLAQNFAACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGDEIAQVAEALKQE--PRANTQVAERILQDLRSQQ
--------------------------------
>NC_007168.1|c1|525545-526822|+|YP_252426.1|HMG-CoA_reductase
-------MKSLDKTFRHLSREDKLKQLVDYGWLTDESYDVLL------KNPLINEEVANS
LIENVIGQGTLPVGLLPKIIVDDKEYVVPMMVEEPSVVAAASYGAKLVNNTG--GFKTVK
SERLMIGQIVFDDVSDTDA--LAQAIYDLEPQ---IKQIAAEAYPSIIERGGGYRRIEID
TFP------ENQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAHMKN
EFPN-RDVLMSILSNHAT-ASVVRVQGEIDIKDL-----NK--GDRSGEEVAQRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDEQYRGIATWKFDKER
GRLVGTIEVPMTLAIVGGGTKVLPIAKASLELLNVQ-SAQELGQVVAAVGLAQNFSACRA
LVSEGIQKGHMSLQYKSLAIVVGAQGDEIARVAEALKAA--PKANTAIAQQILKDLRQQ-
--------------------------------
>NZ_ACPZ01000005.1|c1|37242-38522|-|ZP_04676838.1|hydroxymethylglutaryl-CoA_reductase,
-------MKKLDKGFRHLSREDKLEQLESYGWLSSDNHDILL------NHPLIDEDVANS
LIENVIGQGTLPVGLLPEIIVDDQSYVVPMMVEEPSVVAAASYGAKLVNNTG--GFKTVS
SQRLMIGQIVFDGVTDTES--LSQAIQDKEDQ---IHQIADEAYPSIKARGGGYQKIEID
SFP------DQQ----------------LLSLKVYVDTKDAMGANMLNTILEAITAHLKN
EFPD-EDVLMSILSNHAT-ASVVKIQGEIDIKDL-----NK--GGRDGEAVARRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGIATWTYDQER
QRLIGTIEVPMTLAIVGGGTKVLPIAKASLDLLNVK-SAQELGHVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIIVGAKGDEIAQVADALKQE--DKANSAKAKAILEQIRQDK
--------------------------------
>NC_004461.1|c3|2152086-2153363|-|NP_765664.1|hydroxymethylglutaryl-CoA_reductase
-------MKSLDKGFRHLTRKDKLKKLVEYGWLDDENYEILL------NHPLINEEVANS
LIENVIGQGALPVGLLPRIIVDDKEYVVPMMVEEPSVVAAASYGAKLVNQSG--GFKTIS
SERLMIGQIVFDDVEDTGT--LANSIYQIESQ---IHQIADEAYPSIKARGGGYQRIEID
TFP------NHR----------------LLSLKVFVDTKDAMGANMLNTILEAITAHLKV
KFSN-QNVLMSILSNHAT-ASVVKVQGEIDIEDL-----HR--GERSGEEVAQRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGVEASAHAYASKDGHYRGIATWEYDRSR
NKLVGTIEVPMTLATVGGGTKVLPIAKASLNLLNVE-NAQELGQVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGEEIAQVAEALKYE--SQANTAKAQEILMNIRKS-
--------------------------------
>NZ_ADMU01000021.1|c1|20342-21619|-|ZP_06613901.1|hydroxymethylglutaryl-CoA_reductase
-------MKSLDKGFRHLTRKDKLKELVEYGWLEDENYEILL------NYPLINEEVANS
LIENVIGQGALPVGLLPQIIVDGKEYVVPMMVEEPSVVAAASYGAKLVNQSG--GFKTIS
SERLMIGQIVFDDVDDTGS--LANSIYQIESQ---IHQIADEAYPSIKARGGGYQRIEID
TFP------DQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAHLKV
KFSN-QNVLMSILSNHAT-ASVVKVQGEIDIEDL-----HR--GERSGEVVAQRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGVEASAHAYASKDGHYRGIATWEYDRSR
NKLVGTIEVPMTLATVGGGTKVLPIAKASLDLLNVE-NAQELGQVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGEEIAQVAEALKYE--SQANTAKAQEILMNIRES-
--------------------------------
>NZ_ACJC01000155.1|c1|14692-15969|+|ZP_04798122.1|hydroxymethylglutaryl-CoA_reductase
-------MKSLDKGFRHLTRKDKLKELVEYGWLEDENYEILL------NYPLINEEVANS
LIENVIGQGALPVGLLPQIIVDGKEYVVPMMVEEPSVVAAASYGAKLVNQSG--GFKTIS
SERLMIGQIVFDDVDDTGS--LANSIYQIESQ---IHQIADEAYPSIKARGGGYQRIEID
TFP------DQQ----------------LLSLKVFVDTKDAMGANMLNTILEAITAHLKV
KFSN-QNVLMSILSNHAT-ASVVKVQGEIDIEDL-----HK--GERSGEVVAQRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGVEASAHAYASKDGHYRGIATWEYDRSR
NKLVGTIEVPMTLATVGGGTKVLPIAKASLDLLNVE-NAQELGQVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIVVGAKGEEIAQVAEALKYE--SQANTAKAQEILMNIRES-
--------------------------------
>NZ_ACJB01000022.1|c1|55060-56337|-|ZP_04817763.1|hydroxymethylglutaryl-CoA_reductase
-------MKSLEKGFRHLSREDKLKQLVEYGWLHTDNYESLL------NQPLINEEVANS
LIENVIGQGALPVGLLPKIVVDDKEYVVPMMVEEPSVVAAASYGAKLVNQSG--GFKTIS
SQRLMIGQIVFDGVEDTEQ--LSSDIERLESQ---IHQIADEAYPSIKERGGGYQRIEID
TFP------EQN----------------LLSLKVFVDTKDAMGANMLNTILEAITAHLKN
EFPD-KEVLMSILSNHAT-ASVVKVQGEIDVKDL-----NR--GERSGEDVAYRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGHYRGIATWEYDKDR
GKLIGTIEVPMTLAIVGGGTKVLPIAKASLDLLNVE-TAQELGHVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIVVGAEGEEIAKVAEALKQE--PRANTAKAKEILENIRQS-
--------------------------------
>NZ_ACFR01000001.1|c1|87840-89117|+|ZP_03612671.1|hydroxymethylglutaryl-CoA_reductase,
-------MKSLEKGFRHLSREDKLKQLVEYGWLSTDNYDSLL------SHPLINEEVANS
LIENVIGQGTLPVGLLPKIIVDDKEYVVPMMVEEPSVVAAASYGAKLVNQSG--GFKTIS
SQRLMIGQIVFDDIEDTEQ--LSKDIQALEPQ---IHQIADEAYPSIKERGGGYQRIEID
TFP------EQH----------------LLSLKVYVDTKDAMGANMLNTILEAITAHLKN
EFPE-KDVLMSILSNHAT-ASVVKVQGEIDVNDL-----NR--GERSGEEVAHRMERASV
LAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGIATWKYDKER
GKLIGTIEVPMTLAIVGGGTKVLPIAKASLDLLNVA-SAQELGHVVAAVGLAQNFSACRA
LVSEGIQQGHMSLQYKSLAIVVGAQGEEIAKVAEALKHE--TRANTAKAKEILEELRQS-
--------------------------------
>NZ_GG670306.1|c1|1234224-1235483|-|ZP_05675897.1|acetyl-CoA
---------MAKKKFYQLTPSERRSQLVEKGVLTQENALIF-------EEQTLSEELSDH
MIENQVSEVEIPMGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKI---CG--DICAET
PQRLMRGQIVLSGKSEYQA--VIDAVNHRKEE---LILCANESYPSIVKRGGGVQDISTR
EFMGS----FHA----------------YLSIDFLVDVKDAMGANMINSILESVADKLRG
WFPE-EEILFSILSNFAT-ESLASACCEIPFERL-----GR--SKEIGEQIAKKIQQAGE
YAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAARNGLYQGLTDWQIKENK
--LVGKLTVPLAVATVGGASNILPKAKVSLAMLDVD-SAKELAQVMAAVGLAQNLAALRA
LVTEGIQKGHMGLQARSLAISIGAVGEEIEQVAQKLREA--EKMNQQTAIQLLEKIREK-
--------------------------------
>NZ_ABQA01000004.1|c1|8146-9336|+|ZP_06681281.1|hydroxymethylglutaryl-CoA_reductase,
--------------------------------MTQENALIF-------EEQTLSEELSDH
MIENQVSEVETPMGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKI---CG--NICAET
PQRLMRGQIVLSGKSEYQA--VINAVNHRKEE---LILCANESYPSIVKRGGGVQDISTR
EFMGS----FHA----------------YLSIDFLVDVKDAMGANMINSILESVANKLRE
WFPE-EEILFSILSNFAT-ESLASACCEIPFERL-----GR--SKEIGEQIAKKIQQAGE
YAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAARNGLYQGLTDWQIKENK
--LVGKLTVPLAVATVGGASNILPKAKVSLAMLDVD-SAKELAQVMAAVGLAQNLAALRA
LVTEGIQKGHMGLQARSLAISIGAVGEEIEQVAQKLREA--EKMNQQTAIQLLEKIREK-
--------------------------------
>NZ_GG670388.1|c1|20314-21492|+|ZP_05647279.1|hydroxymethylglutaryl-CoA_reductase
---------------------------------------MVF------QEMTLNKETANH
LIENQISEVEIPLGVGLNLQVNGKAYNVPLATEEPSVIAAMSNGAKM---AG--PITTTS
QERLLRGQIVFMDVQDPEA--ILAKVESEQAT---IFAVANETYPSIVKRGGGLRRVIGR
NFSPAESDLATA----------------YVSIDLMVDVKDAMGANIINSILEGVAELFRK
WFPE-EEILFSILSNLAT-ESLVTATCSVPFDKL-----SK---TGNGRQVAGKIVHAAD
FAKIDPYRAATHNKGIMNGVEALILATGNDTRAVSAACHGYAARNGRMQGLTSWTIIEDR
--LIGSITLPLAIATVGGATKILPKAQAALALTGVE-TASELASLAASVGLVQNLAALRA
LVSEGIQQGHMSMQARSLAISVGAKGTEIEQLAAKLRAA--TQMNQEQARKFLTEIRN--
--------------------------------
>NZ_GG670300.1|c2|1947870-1949033|+|ZP_05656194.1|hydroxymethylglutaryl-CoA_reductase
--------------------------------------------------MTLNKETANH
LIENQISEVEIPLGVGLNLQMNGKAYNVPLATEEPSVIAAMSNGAKM---AG--PITTTS
QERLLRGQIVFMDVQDPEA--ILAKVESEQAA---IFAVANETYPSIVKRGGGLRRVIGR
NFSPAESDLATA----------------YVSIDLMVDVKDAMGANIINSILEGVAELFRK
WFPE-EEILFSILSNLAT-ESLVTATCLVPFDKL-----SK---TGNGRQVAEKIVHAAD
FSKIDPYRAATHNKGIMNGVEALILATGNDTRAVSAACHGYAARNGRMQGLTSWTIIEDR
--LIGSITLPLAIATVGGATKILPKAQAALALTGVE-TASELASLAASVGLVQNLAALRA
LVSEGIQQGHMSMQARSLAISVGAKGTEIEQLAAKLRAA--TQMNQEQARKFLTEIRN--
--------------------------------
>NC_008527.1|c2|1571437-1572669|-|YP_809583.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
----------MRKKFYQMSPQERLNSLN----LSEKSQEIL-------SEMALDTTILDN
LIENQISEFELPMGIAQNFVINGQSFLIPMVTEEPSVIAAASNGAKI---AG--NFVAEI
KERLMRGQIVFYDVKNSDK--IANEILEKQEK---IFEQAELSYPSIVKRGGGLREVSSR
IFS------SQK----------------FLSVDVKVDVKDAMGANIINSILEGIAELFRR
WFPD-EKILFSILSNYAT-ESLVKVTCEIPVERL-----SK---KADGYEIGQKIMAASQ
YSKIDPYRASTHNKGIMNGINAVILATGNDTRAISAAIHAYAAKDGAYQGLANWELQE--
KMLVGELEIPLSVATVGGGVKVLPKAQAAMEILDIS-DAKELAKVIAAVGLAQNLAALRA
LVSEGIQQGHMSLQARSLALSVGAQADEIAILSQQLRKE--KVMNQEVAQNLLKNLRK--
--------------------------------
>NC_009004.1|c1|901117-902349|+|YP_001032255.1|MvaA_protein
----------MRKKFYQMSPQERLNSLN----LSEKSQEIL-------SEMALDTTILDN
LIENQISEFELPMGIAQNFVINGQSFLIPMVTEEPSVIAAASNGAKI---AG--NFVAEI
KERLMRGQIVFYDVKNSDK--IANEILEKQEK---IFEQAELSYPSIVKRGGGLREVSSR
IFS------SQK----------------FLSVDVKVDVKDAMGANIINSILEGIAELFRR
WFPD-EKILFSILSNYAT-ESLVKVTCEIPVERL-----SK---KADGYEIGQKIMAASQ
YSKIDPYRASTHNKGIMNGINAVILATGNDTRAISAAIHAYAAKDGAYQGLANWELQE--
KMLVGELEFPLPVATVGGGVKVLPKAQAAMEILGIS-DAKELAKVIAAVGLAQNLAALRA
LVSEGIQQGHMSLQARSLALSVGAQADEIAILSQQLRKE--KVMNQEVAQNLLKNLRK--
--------------------------------
>NC_002662.1|c1|1610684-1611916|-|NP_267726.1|hydroxymethylglutaryl-CoA_reductase
----------MRKKFYQMSPKERLDSLN----LSEDTQEVL-------SEMALDTNILNN
LIENQISEFELPMGLAQNFVINGKEYIVPMVTEEPSVIAAASNGAKIAE-----SFTAKI
DERLMRGQIVFYDVKKPEE--IIKKISECKNE---IFEQAKLSYPSIIKRGGGLREISSR
LFS------SEK----------------FISVDFKVDVKDAMGANIINSILEGVAELFRG
WFSE-EKILFSILSNYAT-ESLVKVSCEISVDAL-----SK---KTNGLEIAQKIAVASQ
YSKIDPYRASTHNKGIMNGINAVILATGNDTRAISAAIHAYAAKEGTYQGLAKWEVHAEK
--LFGELEIPLPVATVGGGVKVLPKAQAAMEILGIT-DARELAKVIAAVGLAQNLAALRA
LVSEGIQQGHMSLQARSLALSVGAKADEIAVISQQLRQE--KVMNQEVARRLLNSLRN--
--------------------------------
>NC_013656.1|c3|1750992-1752224|-|YP_003354113.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
----------MRKKFYQMSPKERLDSLN----LSEDTQEVL-------SEMALDTNILNN
LIENQISEFELPMGLAQNFVINGKEYIVPMVTEEPSVIAAASNGAKIAE-----SFTAKI
DERLMRGQIVFYDVKKPEE--IIKKISECKNE---IFEQAKLSYPSIIKRGGGLREISSR
LFS------SEK----------------FISVDFKVDVKDAMGANIINSILEGVAELFRG
WFSE-EKILFSILSNYAT-ESLVKVSCEIPVDAL-----SK---KSNGLEIAQKIAVASQ
YSKLDPYRASTHNKGIMNGINAVILATGNDTRAISATIHAYAAKEGTYQGLAKWEVHAEK
--LFGELEIPLPVATVGGGVKVLPKAQAAIEILEIT-DARELAKVIAAVGLAQNLAALRA
LVSEGIQQGHMSLQARSLALSVGAKADEIAVVSQQLRQE--KVMNQELARRLLNHLRN--
--------------------------------
>NC_013515.1|c1|1412518-1413738|-|YP_003306620.1|hydroxymethylglutaryl-CoA_reductase,
----------MWKDSYKKSREDRIKLLKENGNISEDTFNILN------DSDVLSDEMADK
FIENQIGVYGIPLGLATNFLINGKEYIIPFAIEEPSVIAAACNAAKIIKKSG--GFKAQI
TDRLIIGQIAIYDVKDFEK--AKNDIYSIKDR---LLKIANDSQKSIVNLGGGARDIKLE
K--------KED----------------FLIIYLYVDAVDAMGANTVNTMLESIAPVIV-
EICL-GTKLMSIISNYST-SSMVKAECFVEIE----------------EDLGKKIEKAIE
FANADIYRAVTNNKGIFNGIDAISLATGNDWRAIEAGAHAYASRDGKYKSLTSWKYKN--
GILHGIIELPLAIASFGGSVGVHPTSKISLEILGNL-NAKELSEITACVGLAQNFAALRA
LVTVGIQKGHMKLQLKSFAMYLGLEDEKIKILEKEFENE--THITLDKVKEKIKYID---
--------------------------------
>NZ_ABHH01000002.1|c1|83811-85112|+|ZP_02184034.1|hydroxymethylglutaryl-CoA_reductase
------MDKTYLDKFYKKSPTERKKALVAADVLTADDF-LLT------HNLHLADELADN
MIENYLANYELPLGVALNFLVDDKDYIVPMAIEEPSVIAAASAGAKIIAQAS--GFKTTI
SDRIMIGQVALKEVPDLTL--AKSNLAKYKQD---ILKKANEAHPSIVKRGGGATELFVR
VIEANPEAATPA----------------FLMVHLHVSTLEAMGANIINTMMEGITAYLE-
ELTG-GTALMSILSNYAT-ECLATAVCQIPVHLL-----KRPNSNYSGEEVRDRLIEAGQ
LAYVDPYRAVTHNKGIMNGIDAVVLASGNDWRAISAGAHAYASRSGQYRALSTWK-KAEN
GDLIGQLTLPLPVGSVGGSISIHPAAQFSKRLLGYE-SAKELEAVIVSVGLAQNFSALKA
LVTEGIQKGHMGLQARSLAISAGATGTAIEQVAEQLKHA--KNMNLATAKELLSHINVLD
N-------------------------------
>NZ_AAWV02000001.1|c1|1088663-1089952|-|ZP_04431165.1|hydroxymethylglutaryl-CoA_reductase,
------MEKQPLHKFYEKNRLERIKALEQAKAISAEDAALLE------KGLVLPDETADH
MIENQIAKYELPYGTALNFLIDGKEYVVPMAIEEPSVVAAASSAAKIINKAG--GFRTTV
SNRMMIGQVALMEVPDPIR--AKTVVMAHEEE---LLQTANEAKPSIVKRGGGARKLEVR
LIPADEKAGTPA----------------FFVVHLHIDTLEAMGANIIDTMAEAIKPHLE-
EWTG-GRALMGILSNYAT-ECLATAECRIPVSLL-----EK--NGMSGEEVRDRIIEAAQ
FAYADPYRAATHNKGIMNGVDAVVIATGNDWRAIEAGAHAYAARSGKYRSLSIWS-KAEN
GDLLGSLTLPLPVGTVGGQISIHPAAGFSKRLLGYQ-NAKELESIIVSAGLGQNFSAIKA
LVTDGIQKGHMALHAKSLAITAGASGSEIDRVAEKLKQS--GTIDLATAKEILKEIRG--
--------------------------------
>NZ_ACDZ02000008.1|c1|175017-176285|-|ZP_04776430.1|hydroxymethylglutaryl-CoA_reductase,
-------MGKIWSGFYKKNINERLEVIEQADILSEEYLSVLK------NNEVLDFDMANN
MVENVIGTFSLPFSVVPNFVVDDKEYVVPFVTEEPSVVAACSNAGKIVAKSG--GFKTEV
LDRKMVGHVALYNIADTDE--AVERILQSKDL---LLKTADEAYPSIVARGGGARDIEVK
VLSED----GTD----------------FVVVYLIVDTLEAMGANMLNTMLEALKVSLE-
SLTE-GVVLMAILSNYAT-RSLVTAKCAIPFENL-----G-----ENGEYLAQRIELASK
FAKADVYRAATHNKGIFNGIDSVVIASGNDWRAIEAACQSYAAKDGKYQGLSTWRCDEEA
KMLIGEITSPMPVASVGGSIGINPTVKVSRGLLNNP-DAKTLASILVSVGLAQNLAALKA
LVGDGIQKGHMKLHAKSLAILAGATNDNIELIVEELRKE--KHMNLASAKKIVERCNK--
--------------------------------
>NC_013192.1|c2|936160-937452|-|YP_003163749.1|hydroxymethylglutaryl-CoA_reductase,
-MKKENQKKLNWLGFQKKERLERIQMLKANGFLTDEFEQILK------KNENLPLETANQ
MAENGIGTFALPFSIAPNFVIDGKDYAVPMVTEEPSVVAGCSYAAKIIGKSG--GFTTEI
LDRKMIGQVALYDILDFEN--AISMILENKNE---ILKIANDAHPSIVARGGGAINIEVK
N--------IDE----------------FLIVYLIADVKEAMGANILNTMLEAIKIPLE-
NITN-GKSLMAILSNYAT-ESLVKAECEVNVKLL-----SS--SMETSIETAKKIELASK
FSKLDIYRATTHNKGIFNGIDAVVIATGNDWRAIEAGGNAFAVKNGKYEGLTTWTFDEST
NKLKGELILPMPIASVGGSIGLNPSVKAAFNILGNP-DARTLASIITSVGLAQNFAAVKA
LVTTGIQHGHMKLQARSLALFAGAKGKEIDIIVERLLES-GKSINLENVKKILEEIKSTR
--------------------------------
>NZ_ADAD01000030.1|c1|24892-26322|-|ZP_06010848.1|hydroxymethylglutaryl-CoA_reductase,
----MKNNKNIWLGFHNKDKNTRINILKENDFLNEEYSEILK------SNVTLPCEIAGQ
MSENNLGTFALPFGIAPNFLINEKEFAVPMVTEEPSVVAACSYAAKIISRSG--GFTAEV
INRKMTGQVVLYDVNDINT--AIENIEKNKDL---ILKIANEAHPSIVVRGGGAEDVKVQ
AFS------EKNITNNSSITADSDITADFLTVYLIADVKEAMGANIINNMLEGIKPLLE-
DITK-GTALMSILSNYAT-ESLITASCEIDIKYL-----SN--DISYAANVAKKIGLAGK
YAKIDMYRASTHNKGIFNGIDAVLIATGNDWRAIEAGGHAYAVKNGRYEGLTDWTFNPET
NKIKGKLTLPMPIASVGGSIGLNPTVKAAFNILGNP-DAKTLSQIIVSVGLAQNFAALKA
LVTTGIQKGHMKLQAKSLALLAGADPEQIDTVVEKLLEA--RHMSLEKAKEIIKVLKEPF
YSEANINRLEKSIENVESGKSALKEHELIETE
>NZ_AAFA03000010.1|c1|8857-10143|+|ZP_03624915.1|hydroxymethylglutaryl-CoA_reductase,
--------MSTFSGFYKKSRQERIDILRQNRSLSEDSLDILY------KDENLPEAIAGK
MAENHLGTFSLPFSVLPELLVDGQTYSVPMVTEEPSVVAAASFGAKIIAKSG--GFTTTI
HNRIMIGQVALYDISDHSR--ATQAILDHKES---ILETANQAHPSIVKRGGGARELTVE
S--------KDE----------------FLIVYLQVDVQEAMGANVLNNMLEAIKDDLE-
ELSK-GQALMGILSNYAT-ESLVTAQCHIAISSL-----AT--SSAIAQETAQKIALASK
LAQVDPYRAATHNKGIFNGIDAVVIATGNDWRAVEAGAHAYASRDGQYKGLSTWSIDGEH
--LVGSITLPLPIASVGGSIGLNPKVAVAFDLLQQP-KARQLASIIASVGLCQNFAALRA
LVTSGIQAGHMKLHAKSLALLAGAEEHEVDQLAQLLRKE--KHSNLETAQNLLAKMREHW
EWERTRPR------------------------
>NC_009442.1|c1|1556743-1558023|+|YP_001199008.1|hydroxymethylglutaryl-CoA_reductase
--------MSTFSGFYKKSRQERIDILRQNRSLAEDSLDILY------KDENLPEAIAGK
MAENHLGTFSLPFSVLPELLVDGQTYSVPMVTEEPSVVAAASFGAKIIAKSG--GFTTTI
HNRIMIGQVALYDISDHSR--ATQAILDHKES---ILENANQAHPSIVKRGGGARELTVE
S--------KDE----------------FLIVYLQVDVQEAMGANILNNMLEAVKDDLE-
ELSK-GQALMGILSNYAT-ESLITAQCHIAISSL-----AT--SSAIAQETAQKIALASK
LAQVDPYRAATHNKGIFNGIDAVVIAAGNDWRAVEAGAHAYASRDGQYKGLSTWSIDGEH
--LVGSITLPLPIASVGGSIGLNPKVAVAFDLLQQP-KARQLASIIASVGLCQNFAALRA
LVTSGIQAGHMKLHAKSLALLAGAEEHEVDQLAQLLRKE--KHSNLETAQNLLAKMREHW
EWERHP--------------------------
>NZ_ADMV01000012.1|c1|228576-229850|+|ZP_06611616.1|hydroxymethylglutaryl-CoA_reductase
-------MKRSWNGFSKKSYHERLELLKAQALLSPEKQTSLE------QDEQVSLAVADQ
LSENVVGTFSLPYSIIPELVVNGKDYTVPYVTEEPSVVAAASYASKIIKRAG--GFTAQV
HERQMIGQVALYQVADPEQ--AQEKIASKKAE---LLELANQAYPSIVKRGGGARDLHVE
QIKG-----ETD----------------FLVAYLHVDTQEAMGANMLNTMLEALKPVLE-
ELSQ-GQSLMGILSNYAT-DSLVTASCRIAFRYL-----SP--QRDQGREIAEKIALASQ
FAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGLSQWTLDMEK
EELVGQMTLPMPVATKGGSIGLNPRVALSHELLGNP-SAKELAQIIVSIGLAQNFAALKA
LVSTGIQQGHMKLQAKSLALLAGASESEVAPLVERLIAD--KTFNLETAQRYLENLRS--
--------------------------------
>NZ_GG730097.1|c1|986902-988176|-|ZP_06199477.1|3-hydroxy-3-methylglutaryl-CoA_reductase
-------MKISWNGFSKKSYHERLELLRAQALLSPEKQRSLE------QDEQVSLTVADQ
LSENVVGTFSLPYSIIPELLVNGQDYTVPYVTEEPSVVAAASYASKIIKRAG--GFAAQV
HQRQMIGQVALYQVAEPEQ--AQEKITSKKAE---LLELANQAYPSIVKRGGGARDLHVE
QIKG-----EAD----------------FLVVYLHVDTQEAMGANMLNTMLEALKPVLE-
ELSQ-GQSLMGILSNYAT-DSLVTASCRIAFRYL-----SP--QRDQGREIAEKIALASQ
FAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGLSQWTLDMER
EELVGEMTLPMPVATKGGSIGLNPRVALSHELLGNP-SAKELAQIIVSIGLAQNFAALKA
LVSTGIQQGHMKLQAKSLALLAGASESEVAPLVERLIAD--KTFNLETAQRYLENLRS--
--------------------------------
>NC_013853.1|c1|1667523-1668797|-|YP_003446720.1|3-hydroxy-3-methylglutaryl-coenzyme_a_reductase
-------MKISWNGFFKKSYQERLELLKAQALLSPERQGSLE------QDEQMSVTVADQ
LSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAACYASKIIKRAG--GFNAQV
HERQMIGQVALYQVADSDL--ALEKISDKKAE---LLELANQAYPSIVKRGGGARDLHVE
QIKG-----ETD----------------FLVVYLHVDTQEAMGANMLNTMLEALKPVLE-
ELSQ-GQSLMGILSNYAT-DSLVTASCRIAFRYL-----SR--QKDQGREIAEKIALASQ
FAQADPYRAATHNKGIFNGIDAILIATGNDWRAIESGAHAFASQDGRYQGLSRWTLDLER
EELVGEMTLPMPVATKGGSIGLNPRVALSHELLGNP-SAKELAQIIVSIGLTQNFAALKA
LVSTGIQQGHMKLQAKSLALLAGASESEVACLVERLIAD--KTFNLETAQRYLENLRS--
--------------------------------
>NC_011900.1|c2|1669483-1670757|-|YP_002511613.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
-------MKISWNGFSKKSYQERLELLKAQALLSPERQASLE------KDEQMSVTVADQ
LSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAG--GFTAQV
HQRQMIGQVALYQVANPKL--AQEKIASKKAE---LLELANQAYPSIVKRGGGARDLHVE
QIKG-----EPD----------------FLVVYIHVDTQEAMGANMLNTMLEALKPVLE-
ELSQ-GQSLMGILSNYAT-DSLVTASCRIAFRYL-----SR--QKDQGREIAEKIALASQ
FAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGLSCWTLDLER
EELVGEMTLPMPVATKGGSIGLNPRVALSHDLLGNP-SARELAQIIVSIGLAQNFAALKA
LVSTGIQQGHMKLQAKSLALLAGASESEVAPLVERLISD--KTFNLETAQRYLENLRS--
--------------------------------
>NC_003028.3|c2|1629797-1631071|-|NP_346163.1|3-hydroxy-3-methylglutaryl-CoA_reductase
-------MKISWNGFSKKSYQERLELLKAQALLSPERQASLE------KDEQMSVTVADQ
LSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAG--GFTAQV
HQRQMIGQVALYQVANPKL--AQEKIASKKAE---LLELANQAYPSIVKRGGGARDLHVE
QIKG-----EPD----------------FLVVYIHVDTQEAMGANMLNTMLEALKPVLE-
ELSQ-GQSLMGILSNYAT-DSLVTASCRIAFRYL-----SR--QKDQGREIAEKIALASQ
FAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGLSCWTLDLER
EELVGEMTLPMPVATKGGSIGLNPRVVLSHDLLGNP-SARELAQIIVSIGLAQNFAALKA
LVSTGIQQGHMKLQAKSLALLAGASESEVAPLVERLISD--KTFNLETAQRYLENLRS--
--------------------------------
>NC_009009.1|c1|330979-332253|-|YP_001034344.1|hydroxymethylglutaryl-CoA_reductase,_putative
-------MKVNWTGFSKKNPAERLQMLKEKGLLQDEHWQLLD------SQQTLPLETANQ
MSENVLATLALPYSLVPDFLVDGKSYQVPFVTEEPSVVAAASFAAKIIKRSG--GFETEV
HKRQMIGQIALYQVDNADR--AIKDILMKKKE---LLEQANQAYPSIVARGGGARDLWLE
P--------KED----------------FLIFYLSVDTQEAMGANMLNTMLEAITLPLK-
DLTG-GKSLMAILSNYAT-DSLVTARCVIGYRFL-----SR--DTAEAELLADKMQLASK
LAQVDPYRAATHNKGIFNGIDALVLATGNDWRAVEAGAHAYASREGSYRGLSTWTADPDK
RQLHGQMTLPMPIATKGGSIGLNPAVAASFDLLGQP-QAKELASLIVSVGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALQAGAQGEEIAAVASCLTVK--KTFNLATAQEILADLRKQD
K-------------------------------
>NZ_GG704939.1|c1|271566-272840|-|ZP_06059648.1|hydroxymethylglutaryl-CoA_reductase
-------MKINWTGFSKKTPAERLQMLKEKELLQDEHWQLLD------SQQTLPLETANQ
MSENVLATLALPYSLVPDFLVDGKTYQVPFVTEEPSVVAAASFAAKIIKRSG--GFETEV
HKRQMIGQIALYQVDNADQ--AIKDVLRKKKE---LLEQANQAYPSIVARGGGARDFWLE
Q--------KDD----------------FLIFYLSVDTQEAMGANMLNTMLEALTLPLE-
ELTG-SKSLMAILSNYAT-DSLVTARCVIDYRFL-----SR--NKAEAELLADKMQLASK
LAQVDPYRAATHNKGIFNGIDALVLATGNDWRAVEAGAHAYASREGSYRGLSTWTADPDK
RQLHGQMTLPMPIATKGGSIGLNPAVAASFDLLGQP-QAKELASIIVSVGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALQAGAQGEEIVAVASRLTAK--KTFNLAAAQEILADLRKQD
K-------------------------------
>NC_009785.1|c1|259985-261259|-|YP_001449562.1|hydroxymethylglutaryl-CoA_reductase,
-------MKINWTGFSKKTPAERLQILKEKGLLQDEHWQLLD------SQQTLPLETANQ
MSENVLATLALPYSLVPDFLVDGKTYQVPFVTEEPSVVAASSFAAKIIKRSG--GFETEV
HKRQMIGQIALYQVDNADQ--AIKDVLRKKKE---LLEQANQAYPSIVARGGGARDLWLE
Q--------KDD----------------FLIFYLSVDTQEAMGANMLNTMLEALTLSLE-
ELTG-GKSLMAILSNYAT-DSLVTARCVIDYRFL-----SR--DKAEAELLADKMQLASK
LAQADPYRAATHNKGIFNGIDALVLATGNDWRAVEAGAHAYASREGSYRGLSTWTVDPDK
RQLHGQMTLPMPIATKGGSIGLNPAVAASFDLLGQP-QAKELASLIVSVGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALQAGAQGEEIAAVASHLTAK--KTFNLAAAQEILADLRKQD
K-------------------------------
>NC_012004.1|c1|747978-749258|-|YP_002562107.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
------MPKLNWSGFYKKTPQERMQLLKEYQLLDERSEDILM------QQELLSLETANQ
MTENVVGRLALPFSIVPDVFVNGKTYHIPMVTEEPSVIAAASFAAKIIKRCG--GFKTKV
HNRQMIGQVALYDLEDMEV--AKLAILTQKDD---LINLANQAYPSIVKRGGGARELSAQ
I--------KDQ----------------FLIIYMTVDTQEAMGANMVNTMMEAITPELE-
QLSS-GKALMAILSNYAS-ESLVSAECSIDFRFL-----SR--DPNEAKVLAKKMVLASH
LAQIDPYRAATHNKGIFNGIDAVVMATGNDWRAIEAGGHAFAAKDGTYRGLSTWTVDEEN
HCIIGQLTLPMPIATKGGSIGLNPSVQMAHQLLHNP-NAKELAQVIVSLGLAQNFAALKA
LTNTGIQAGHMKLQAKSLALLAGATEKTLPKLVPLLLKE--KHMNLETAKALLQKLDERK
EP------------------------------
>NC_004368.1|c1|1436362-1437645|+|NP_735824.1|hypothetical_protein
------MTKISWTGFSKKSPEERIHYLEEQDFLADSSLEIVT------NQDLLSLSLANQ
MAENVIGRIALPFSLVPDVLVNGKVYQVPYVTEEPSVVAAASFAAKIIKRSG--GFLTTV
HNRKMIGQVALYDVQDSQH--AKESILNQKQQ---LLEIANAAHPSIVKRGGGACDLTIE
I--------KEG----------------FLIVYLMVDTKEAMGANMVNTMMEALSSPLE-
DISK-GKSLMSILSNYAT-ESLVTATCRVDLRFL-----SR--QKEEAIKLAQKMTMASQ
LAQVDPYRASTHNKGIFNGIDAIVLATGNDWRAIEAGAHTYAVKDGQYRGLSKWSYKVDD
NFLEGTLTLPMPVATKGGSIGINPSVQLAHDLLGRP-NAKELASIVLSIGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALLAGAKEEQISEVVKQLLDS--KHMNLETAQKIVNKLTKSK
KRI-----------------------------
>NZ_AAJS01000117.1|c1|1827-2413|+|ZP_00784155.1|Hydroxymethylglutaryl-coenzyme_A_reductase
------MTKISWTGFSKKSPEERIHYLEEQDFLADSSLEIVT------NQDLLSLSLANQ
MAENVIGRIALPFSLVPDVLVNGKVYQVPYVTEEPSVVAAASFAAKIIKRSG--GFLTTV
HNRKMXGQVAIYDVXDSQH--TKESILNQKQQ---LLEIANAAHPSIVKRGGGACDLTIE
I--------KED----------------FLIVYLMVDTKEAMGANMVNTMMEALSSPL--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------
>NZ_AAJR01000044.1|c1|9498-10781|-|ZP_00785881.1|hydroxymethylglutaryl-CoA_reductase,
------MTKISWTGXSKKSPEERIHYLEEQDFLADSSLEIVT------NQDLLSLSLANQ
MAENVIGRIALPFSLVPDVLVNGKVYQVPYVTEEPSVVAAASFAAKIIKRSG--GFLTTV
HNRKMIGQVALYDVQDSQH--TKESILNQKQQ---LLEIANAAHPSIVKRGGGACDLTIE
I--------KED----------------FLIVYLMVDTKEAMGANMVNTMMEALSSPLE-
DISK-GKSLMSILSNYAT-ESLVTATCRVDLRFL-----SR--QKEEAIKLAQKMTMASQ
LAQVDPYRASTHNKGIFNGIDAIVLATGNDWRAIEAGAHTYAVKDGQYRGLSRWSYKVDD
NCLEGTLTLPMPVATKGGSIGINPSVHLAHDLLGRP-NAKELASIILSIGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALLAGAKEEQISEVVKQLLDS--KHMNLETAQKIVNKLTKSK
KRI-----------------------------
>NZ_AAJO01000043.1|c1|7077-8360|-|ZP_00780827.1|hydroxymethylglutaryl-CoA_reductase,
------MTKISWTGFSKKSPEERIHYLEEQDFLADSSLEIVT------NQDLLSLSLANQ
MAENVIGRIALPFSLVPDVLVNGKVYQVPYVTEEPSVVAAASFAAKIIKRSG--GFLTTV
HNRKMIGQVAIYDVQDSQH--TKESILNQKQQ---LLEIANAAHPSIVKRGGGACDLTIE
I--------KED----------------FLIVYLMVDTKEAMGANMVNTMMEALSSPLE-
DISK-GKSLMSILSNYAT-ESLVTATCRVDLRFL-----SR--QKEEAIKLAQKMTMASQ
LAQVDPYRASTHNKGIFNGIDAIVLATGNDWRAIEAGAHTYAVKDGQYRGLSRWSYKVDD
NCLEGTLTLPMPVATKGGSIGINPSVHLAHDLLGRP-NAKELASIILSIGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALLAGAKEEQISEVVKQLLDS--KHMNLETAQKIVNKLTKSK
KRI-----------------------------
>NC_004116.1|c1|1324220-1325503|+|NP_688315.1|3-hydroxy-3-methylglutaryl-CoA_reductase
------MTKISWTGFSKKSPEERIHYLEEQDFLADSSLEIVT------NQDLLSLSLANQ
MAENVIGRIALPFSLVPDVLVNGKVYQVPYVTEEPSVVAAASFAAKIIKRSG--GFLTTV
HNRKMIGQVALYDVQDSQH--TKESILNQKQQ---LLEIANAAHPSIVKRGGGACDLTIE
I--------KED----------------FLIVYLMVDTKEAMGANMVNTMMEALSSPLE-
DISK-GKSLMSILSNYAT-ESLVTATCRVDLRFL-----SR--QKEEAIKLAQKMTMASQ
LAQVDPYRASTHNKGIFNGIDAIVLATGNDWRAIEAGAHTYAVKDGQYRGLSRWSYKVDD
NCLEGTLTLPMPVATKGGSIGINPSVHLAHDLLGRP-NAKELASIILSIGLAQNFAALKA
LVSTGIQAGHMKLQAKSLALLAGAKEEQISEVVKQLLDS--KHMNLETAQKIVNKLTKSK
KRI-----------------------------
>NC_012891.1|c2|831065-832342|-|YP_002996555.1|HMG-CoA_reductase
----MTNMNLNWAGFSKKTFEERLQLIKQFELLTPEHLQTLE------EDCLLPIETANQ
LTENVLGRFALPFSIAPDFLINGVSYQVPFVTEEPSVVAAASFAAKLIKRSG--GFASKV
LKRQMIGQVALYDIDQVEE--AKQTILANSDK---LIAAANDAYPSIVKRGGGAREIRLE
E--------KGD----------------FLIFYLTVDTQEAMGANMVNTMMEALIPDLE-
SLSK-GQSLMAILSNYAT-ESLVTASCQVDIRFL-----SR--DKTEAQQLAKKMVLASQ
LAQADSYRAATHNKGIFNGIDAVVMATGNDWRAIEAGGHAYASRNGAYQGLSHWEFDQEQ
EVLLGQLTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQVIVSVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGAKEEEVAPLVTSLLAD--KPMNLEKASQHLAILRNA-
--------------------------------
>NC_006086.1|c1|705961-707238|-|YP_060021.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDILLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DR--DKTKSLQLAQKIELASR
LAQVDPYRATTHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGQMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGATQDEITPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NC_008021.1|c1|727206-728483|-|YP_596474.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDVLLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DR--DKTKSLQLAQKIELASR
LAQVDPYRATTHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGRMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGATQDEIAPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NC_007296.1|c1|686848-688125|-|YP_280134.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDVLLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DH--DKTKSLQLAQKIELASR
LAQVDPYRATTHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGQMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQTGHMKLHAKSLALLAGATQDEIAPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NC_003485.1|c1|768566-769843|-|NP_607084.1|HMG-CoA_reductase
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDVLLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DR--DKTKSLQLAQKIELASR
LAQVDPYRAATHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGQMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGATQDEIAPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NZ_AAFV01000003.1|c1|8043-9320|+|ZP_00366612.1|COG1257:_Hydroxymethylglutaryl-CoA_reductase
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDVLLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DL--DKTKSLQLAQKIELASR
LAQVDPYRATTHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGQMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGATQDEIAPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NC_008024.1|c1|751564-752841|-|YP_602272.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDVLLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DR--DKTKSLQLAQKIELASR
LAQVDPYRATTHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGQMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGATQDEIAPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NC_002737.1|c1|727593-728870|-|NP_269079.1|putative_3-hydroxy-3-methylglutaryl-coenzyme_A
----MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLK------TDVLLPIQTANQ
MTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG--GFKAQT
LNRQMIGQIVLYDIDQIDN--AKAAILHKTKK---LIALANKAYPSIVKRGGGARTIHLE
E--------KGE----------------FLIFYLTVDTQEAMGANMVNTMMEALVPDLT-
RLSK-GHCLMAILSNYAT-ESLVTTSCEIPVRLL-----DH--DKTKSLQLAQKIELASR
LAQVDPYRATTHNKGIFNGIDAVVIATGNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDK
QVLLGQMTLPMPIASKGGSIGLNPTVSIAHDLLNQP-DAKTLAQLIASVGLAQNFAALKA
LTSSGIQAGHMKLHAKSLALLAGATQDEIAPLVNALLAD--KPINLEKAHFYLSQLRQS-
--------------------------------
>NZ_ACLO01000092.1|c1|162097-163368|+|ZP_04062874.1|hydroxymethylglutaryl-CoA_reductase,
------MTKLSWTGFSKKTPQERKEHLKTNALLSQENQNLLD------KDQQLTLETANQ
MAENVIGRFTLPFAICPDVLVDGVTYQVPMVTEEPSVVAAASYASKLIKRSG--GFATTI
HDRQMIGQVALFDVPDKDD--ASRKIQAASQD---LIEIAKEAHPSIVKRGGGPRKLWTE
T--------KGD----------------FLIVYLAVDTQEAMGANMVNTMMEALVPELE-
NLSK-GQSLMAILSNLAT-ESLVTATCRLSTRFL-----SR--NKEEAHDLAKKMEMASQ
LAQVDPYRAATHNKGIFNGIDALVIATGNDWRAVEAGSHAFASKDGSYRGLSTWTYDQEA
KELVGELTLPMPIATRGGSIGLNPSASIAHDLLNHP-DAKTLASIIVSLGLAQNLAALKA
LTSTGIQAGHMKLQAKSLALLAGASPEEMPQVLAELLKA--KHMNQETAQAILEKLRTP-
--------------------------------
>NC_008532.1|c2|562549-563820|-|YP_820083.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
------MTKLSWTGFSKKTLQERKEHLKNNALLSQENQDLLD------NDQQLTLETANQ
MAENVIGRFTLPFAICPDVLVDGVTYQVPMVTEEPSVVAAASYASKLIKRSG--GFTTKI
HDRQMIGQVALFDVPDKAT--AASKIQAASQK---LIDIAKEAYPSIVKRGGGPRKLWTE
T--------KGD----------------FLIVYLAVDTQEAMGANMVNTMMEALVPELE-
NLSE-GQSLMAILSNLAT-ESLVTATCRLNTRFL-----SR--NKAEAHNFAKKMELASQ
LAQVDPYRAATHNKGIFNGIDALVIATGNDWRAVEAGCHAYASKDGSYRGLSTWTYNQET
KELVGELTLPMPIATRGGSIGLNPSVSIAHDLLNHP-DARTLAGIIVSLGLVQNLAALKA
LTSTGIQAGHMKLQAKSLALLAGANPEEMPHVLSELLKA--KHMNQETAQAILEKLRNP-
--------------------------------
>NC_006448.1|c3|546146-547417|-|YP_139097.1|3-hydroxy-3-methylglutaryl-coenzyme_A_reductase
------MTKLSWTGFSKKTLQERKEHLKNNALLSQENQDLLD------NDQQLTLETANQ
MAENVIGRFTLPFAICPDVLVDGVTYQVPMVTEEPSVVAAASYASKLIKRSG--GFTTKI
HDRQMIGQVALFDVPDKAT--AASKIQAASQE---LIDIAKEAHPSIVKRGGGPRKLWTE
T--------KGD----------------FLIVYLAVDTQEAMGANMVNTMMEALVPELE-
NLSE-GQSIMAILSNLAT-KSLVTATCRLNTRFL-----SR--NKAEAHNFAKKMELASQ
LAQVDPYRAATHNKGIFNGIDALVIATGNDWRAVEAGCHAYASKDGSYRGLSTWTYNQET
KELVGELTLPMPIATRGGSIGLNPSVSIAHDLLNHP-DARTLAGIIVSLGLVQNLAALKA
LTSTGIQAGHMKLQAKSLALLAGASPEEMPHVLSELFKA--KHMNQETAQAILEKLRNP-
--------------------------------
>NC_004350.1|c1|892870-894153|-|NP_721341.1|putative_hydroxymethylglutaryl-CoA_reductase
MVKSMNPKKINWSGFSRKTLQERLKHLEKHQLLSTEELKKLC------QNQQLPLETANQ
MVENVLGTFSLPFALAPDFLIDGKEYQVPFVTEEPSVVAAASFAAKIIKRSG--GFSTKI
HNRQMLGQVALYDVDDFDK--AHKNILDKKAL---LLSLANEAHPSIVKRGGGACDLMTE
I--------KGS----------------FLIVYLSVDTKEAMGANIVNTMLETLAAPLE-
ELSG-GQSLMAILSNYAT-EALVTAQCQVNLRFL-----SR--DKTKAKKLARKMDLASQ
LAQIDVYRASTHNKGIFNGIDALVLATGNDWRAIEAGGHAYASRDGHYRGLPTWSYDDKN
EILKGKISLPMPIATKGGSIGLNPTVQCAYDLLGNP-TAKELAAIIAAVGLAQNFAALKA
LTSTGIQAGHMKLQAKSLALLAGAKEKEVSTLVSQLLKA--KHMNLETAQTLLKNLR---
--------------------------------
>NZ_ABJK02000012.1|c1|68063-69334|-|ZP_02919507.1|hypothetical_protein
-----MTNKVTWGGFSKKTLAERLEHLEKNELISAERLETLK------NNELLSLETANQ
MAENVLGTFSLPFSLAPDFQIDDKTFNVPMVTEEPSVVAAASFAAKIIKRSG--GFKTQV
HSRKMIGQVALYDVPNKSA--AKKAIVEHTEQ---LISLANDAHPSIVKRGGGARELSID
E--------KDD----------------FLIVYLTVDTQEAMGANMVNTMMEALVPSLE-
ELSG-GKSLMAILSNYAT-ESLVTADCQVDLRYL-----SR--NKEEAQELARKFHLASK
LAQEDVYRASTHNKGIFNGIDAVVMATGNDWRAIEAGANTYACKDGQYRGLATWTFDEEA
QVLRGQLTLPMPIATRGGSIGLNPTVKIAHDLLGHP-DARQLARIIVSVGLAQNFAAIKA
LTSTGIQAGHMKLQAKSLALLAGVKDKEVSEVVKALLEA--PHMNLETAQHILLNLRN--
--------------------------------
