>NC_011991.1|c1|77770-78636|-|YP_002551455.1|3-hydroxyisobutyrate_dehydrogenase
----------------------------MTERPRIGLVGVGKMGRALATRLL-SCGVEVF
GCDPAAQNPP-------D-G--LQ--FVATPRQLADCCDV---VMGCVSGQEAFREVTLG
-PNGIRGG--TRVHTYANVGTTGPSLVKEIAH-GLA-EVD-IRTIDVPMTG--GPRRAAR
G---EVTVIASGPLKVLQ-AVSPTLEKYS----SK--------------------IVYV-
--GPGVGQAQYVKVINNLVTAGNLAVAIEALTLAKKA-----------------------
--TI--SR---ELLLEVIN----S-GSAASDVST-------SKIPSHVLTRTFD-FG-AS
LALVDHDLSCC--LHEARLIDCEMRVSKAVLDVYRSAI----------------------
--------------------------EAG---SALDDIT---------------------
------------------------------------------------------------
-------------------TLAVYLENR-------------------------------
>NC_004547.2|c1|565471-566364|+|YP_048607.1|putative_2-hydroxy-3-oxopropionate_reductase
------------------------------MTHSVSLVGVGVLGKAISLRLL-QRHFSLS
VFNRTHSKTNDVAA---E-G--AQ--AVPELHQLFTQEKQ--IVLICLKDAEAIRDVFQS
--EDVIHKLSLYRPLFLNISTIGPEESRWMET-FFH-QHG-AHYVECPVSG--GPEGARQ
G---RLAAWVGPYADDFASAVNDIVSCLS----DH--------------------YVLM-
--ES-NHSAQTMKVINNYCEAVHLLVAAEALLLAEAH-----------------------
--GI--AP---DVLANALT----L-GRGRSTYMEVMLDRY-------LNPRETV---SVP
LSIRLKDLDLA--NTLFQRSAIHSEFFDTARQLYQSTA----------------------
--------------------------DLS---ADPQDQT---------------------
------------------------------------------------------------
-------------------ACFAYLSRTLPKGRD-------------------------
>NZ_ABCM01000007.1|c1|150074-151474|-|ZP_01884196.1|6-phosphogluconate_dehydrogenase
-----------------------------MNKYTLGMIGLGTMGRNLLLNMA-DNGFSVT
GYDKSADMLKKLEE---D-GKAHQLKGFADLSDFVQSLELPRRIVLLVPAGKIVDSVI--
--EELLPL-LDKGDLIIDSGNSHFTDTTRRSL-ELA-DQG-IHFFGMGISG--GEEGARF
G----PSMMPGGDKKAYE-AVKPILEAVS----AK--------------VNGDPCVTYI-
--GP-GASGHFVKMVHNGIEYSMMQILAETYDLLKNS-----------------------
-LGY--NNEQIYSVFEKWN----E-GRLKSFLLE-VTRDVFKVKDEKTGGYLID----VI
KDEAKSKGTGK--WTSQVSMDLQLPIPTINESVSARDL-----SKFKTLRVELSEALPHV
KEAIDNKEEFEVQLEQAVYFAMITSYAQG---LHLLSQA-SKEYKYELNLQEISQIWRGG
CIIRAVLLEDIYQAYKKQTDLPHLYADAGIQKQLQEIIPGTRNVVITAIKHGVAMPCFAS
ALTYYDSLRTANSPLNLTQAQRDFFGAHTFERTDSEGIFHADWN---------------
>NZ_ABCQ01000022.1|c1|9852-11354|+|ZP_01898864.1|6-phosphogluconate_dehydrogenase
----------------------------MNKNIDIAVIGLGVMGANMALNLA-ERGFSVA
AFDINESRRTDIIKRHQP-LTAAKLIAVADLAELINQLEVPRRIVLSVPAGPVVDIIC--
-NDLIAAG-LEANDIVVDTGNSQWRDSIARAD-TYA-GKF--SFFTCAISG--GEVGARF
G----PSLMPSGDKAAWE-RLKPMWQAMSAKVDPETGVEIARTHVDQPLPEGEPCAEYI-
--GP-IGSGHFVKMVHNGIEYADMQMIAEVVQFMRQI-----------------------
-LGM--SAVEVGEVFSEWN----K-GKLQSYLIE-ITGNILKVVDEATGKPMVD----VI
MDQAGQKGTGN--WTAREALELGVPANAIAESVFARCL-----STQKSIRQVGATKLAGP
TVTIEDRNVWLEKLADALYCSKICSYAQG---FELMSAA-QKEHNWTLDYVAIAKIWRAG
CVIRAHFLDDIAKAYQAEPELLNLMLADRFTNTLAESQMAWREVLAKAIMQGMPMPSISA
AMSYYDCYREADSSASLIQAMRDYFGGHTYRRKDQDASQSFHYDWHFGTGEHKAQH---
>NZ_ACEX01000734.1|c1|35917-37371|-|ZP_05520534.1|6-phosphogluconate_dehydrogenase
----------------------MPSPSSTQPTAQIGVTGLAVMGSNLARNFA-RHGHTVA
VHNRSSAKTKALIE---EHGHEGSFVPAETAAEFVAALQRPRRLVIMVKAGAPTDAVI--
--EEFAPL-LEEGDVIIDGGNAHFDDTRRREK-ALR-ERG-LHFVGTGISG--GEEGALN
G----PSIMPGGSSESYK-SLGPLLESIS----AK--------------VDGTPCCTHI-
--GP-DGAGHFVKMVHNGIEYADMQLIAESYDLLRRA-----------------------
-LGL--TPGEIAEVFRTWN----G-GRLESYLIE-ITAEVLAHTDAATGKPFVD----VV
QDQAEQKGTGR--WTVQTALDLGVPVSGIAEAVFARSL---SGHADVRDASQGLPGPAAK
QLTGKAAERFADEVEQALYASKIVAYAQG---IHQIEAG-SQEYGWDIDPGAVARIWRGG
CIIRARFLNRITEAYGKDNKPVTLLADDYFAQALGEAQDAWRRVVSTSVELGVPAPGFSA
ALAYYDALRSERLPAALVQGQRDFFGAHTYRRTDREGSFHTLWGQDRSEREA-------
>NZ_ABYC01000045.1|c1|2033-3490|+|ZP_04700645.1|6-phosphogluconate_dehydrogenase
----------------------MSETAQPTGTAQIGVTGLAVMGRNLARNFA-RNGYTVA
VHNRTAAKTEELVS---GFGDEGTFLPASTPEELVESLERPRRVLVMVKAGAPTDAVI--
--EEFAPL-LEEGDMIIDGGNAHFEDTRRREK-ALR-ERG-IHFVGTGVSG--GEEGALH
G----PSIMPGGSAASYD-ALGPMLEKIS----AK-------------ADDGTPCVTHV-
--GP-DGAGHFVKMVHNGIEYADMQLIGEAYQLLREV-----------------------
-GGY--SPAEIAEIFRTWN----T-GRLDSYLIE-ITAEVLAHTDAATGEPFVD----VV
LDQAEQKGTGR--WTVQSALDLGVPVSGIAEAVFARAV---SGHADLRKASRHLAGPTPR
KLPEDDAATFADQVEQALYASKIVAYTQG---FHQIAVG-SEQYGWDIDLGRIAAIWRAG
CIIRAAFLDRVTQAYDAQPGMVSLLADQGFADETAAAQDDWRTVVATAVTNGVPTPGFAA
TLAYYDSLRAPRLPAALTQGQRDYFGAHTYHRTDRPGTFHTLWGGDRSETEA-------
>NZ_DS999641.1|c4|815604-816842|+|ZP_06575043.1|6-phosphogluconate_dehydrogenase
----------------------------MSSSAQIGVTGLAVMGRNLARNFA-RNGYTVA
VHNRTAARTHALVE---EFGHEGSFVAAETAKEFVAALERPRRLVVMVKAGEPTDAVI--
--EEFAPL-LEPGDMIIDGGNAHFADTRRRER-ELR-EKG-IHFVGTGISG--GEEGALN
G----PSIMPGGSKESYG-SLGPMLEKIS----AK-------------AADGAPCVTHV-
--GP-DGAGHFVKMVHNGIEYADMQLIGEAYQLLRDV-----------------------
-AGY--SPARIAEIFRTWN----T-GRLDSYLIE-ITAEVLSHVDAATGKPFVD----VV
VDQAEQKGTGR--WTVQIALDLGVPVSGIAEAVFARSL---SGHAALREASRGLAGPKAA
PLGEAEAAAFADRVEQALYASKIVSYTQG---FHEIAAG-SEEYGWDIDLGAVSAILLLS
CF----FF--------------------------------WRPFWTASAPPTTRGP----
------TCRA----CCPTRRSR---GRSPRRRT----------TGARC-----------
>NC_009142.1|c20|4924503-4925942|+|YP_001106590.1|6-phosphogluconate_dehydrogenase
----------------------------MSTSAQIGVTGLAVMGRNLARNFA-RNGYAVA
VHNRTASKTRELMD---EFGQEGDFVAAESAEDFVAALERPRRLVVMVKAGDPTDAVI--
--REFAPL-LEHGDVIIDGGNAHFADTRRRER-ELR-EHG-IHFVGTGISG--GEEGALH
G----PSIMPGGSDESYA-SLGPMLEKIS----AK-------------AADGAPCVTHV-
--GP-DGAGHFVKMVHNGIEYADMQLIAEAYHLLREV-----------------------
-AGF--SPARIAEIFRTWN----T-GRLDSYLIE-ITAEVLSHVDAATGEPFVD----VV
ADQAEQKGTGR--WTVQIALELGLPVSGIAEAVFARSL---SGHTALRAASRGLAGPTPA
PLGESEAAAFADQVEQALYASKIVSYTQG---FHEIATG-SAEYGWNIDLGAVAAIWRAG
CIIRAAFLDRVRAAYDARPDLPSLLSDEAFAREIAAAQDDWRAVLVAATRQGVPTPGFSA
ALTYYDTLRADRLPAALTQGQRDYFGAHTYRRTDREGVFHTLWSGDRSEVPV-------
>NC_013715.1|c1|851839-853311|+|YP_003362444.1|6-phosphogluconate_dehydrogenase
--------------------------MTENKKAQIGVTGLAVMGANLARNLA-RNGYTVA
LHNRSVEKTDALLA---EHGADGDFIRTESLQELVDSLESPRRILIMVKAGAPVDAVI--
--EQLTPL-LDEGDIIIDGGNSHFPDTIRRER-ALA-EKG-LHFVGVGVSG--GEEGALW
G----PSMMPGGSAESYK-HIGPMLEKIA----AK------------APQDGAPCCAWI-
--ST-DGSGHFVKMVHNGIEYADMQVIGEAYDLLRSV-----------------------
-AGI--EPAEQAEIFKTWN----E-GDLSSYLIE-ITAEVLAQVDAKTGKPLVD----VI
VDAAGQKGTGL--WTAKAGLDLGSPVSAIAESVFARALSSSEREQREQAQRELPAGLIAT
TGIGAGDPEFVEDVRRALFASKLVAYAQG---MDLLTRA-GKEYGWDLKLDTIASLWRAG
CIIRAELLGDIMAAYADEA-PANMLLAPAFKNLMEELVPSWRRVVAKATALGIPVPVFAS
ALSYYDGLRRDRLPASLIQGQRDFFGAHTYGRIDEEGAFHTMWSGDRSEVNAADIHVH-
>NZ_ACVO01000001.1|c1|43670-45142|+|ZP_05367056.1|6-phosphogluconate_dehydrogenase,
--------------------------MTENKKAQIGVTGLAVMGANLARNLA-RNGYTVA
LHNRSVEKTDALLA---EHGADGDFIRTESLQELVDSLESPRRILIMVKAGAPVDAVI--
--EQLTPM-LDEGDIIIDGGNSHFPDTIRREH-ALA-EKG-LHFVGVGVSG--GEEGALW
G----PSMMPGGSAESYK-HLGPLLEKIA----AK------------APQDGAPCCAWI-
--ST-DGAGHFVKMVHNGIEYADMQVIGEAYDILRSI-----------------------
-AGI--EPAQQAEIFKTWN----E-GDLSSYLIE-ITAEVLAQVDAKTGKPLVD----VI
VDAAGQKGTGL--WTAKAGLDLGSPVSAIAESVFARALSSSEREQREQAQRELPAGLIAT
TGIGAGDPEFVEDVRRALFASKLVAYAQG---MDLLTRA-GKEYGWDLKLDTIASLWRAG
CIIRAELLGDIMAAYAGEA-PANMLLAPAFKNLMEELVPSWRRVVAKATALGIPVPVFAS
ALSYYDGLRRDRLPASLIQGQRDFFGAHTYGRIDEEGAFHTMWSGDRSEVNAADIHVH-
>NC_010168.1|c5|2959986-2961422|-|YP_001626452.1|6-phosphogluconate_dehydrogenase
------------------------------MSAQIGVTGLAVMGANLARNLA-RNGFTVA
LHNRSVSRTDELLA---KHGDEGNFVRTETLQELVHSLEKPRRVLIMVKAGAPVDSVV--
--DQLVPL-LEEGDIVIDAGNSHYTDTRRREA-DLA-TKG-LHFVGIGVSG--GEEGALN
G----PSIMPGGSKESYQ-ALGPLLEKIS----AH-----------V--D-GQPCCAWI-
--GP-DGAGHFVKMVHNGIEYADMQVIGEAYDLLRSG-----------------------
-AGI--EPAEQAEIFKEWN----K-GTLSSFLIE-ITAEVLGHVDAKTGKPFVD----VV
VDAAGQKGTGR--WTVISALELGSPTSGIAESVFARAL-SSQSAQRVEAQGTLASAEVQ-
--LELGN-DFIEDVRQALFASKLVSYAQG---LDMLTGA-AKEYNWDLKLDEIASLWRGG
CIIRAELLKDITKAYSATDKPGNLLFAPAFTQAIAEALPAWRRVVSTAVQLGIPVPVFSS
SLAYYDGLRRKRLPAALTQGLRDLFGAHTYQRVDVDGTFHTLWGEDKSDIEAVDSH---
>NC_006370.1|c1|1620181-1621680|+|YP_129657.1|6-phosphogluconate_dehydrogenase
-------------MVFRFRRSQSASVKESMMKGDIGVIGLAVMGQNLILNMN-DHGFKVV
AFNRTVAKVDEFLAGPAK-D--TNIIGATSLEDLVANLEAPRKVMLMVRAGDVVDHFI--
--DSLVPL-LDKGDIIIDGGNSNYPDTNRRVA-DLE-AKG-IYFVGTGVSG--GEEGARF
G----PSIMPGGSPEAWP-HVKPIFQVIS----AK-------------TDQGEACCDWV-
--GK-DGSGHFVKMVHNGIEYGDMQLISEAYHFMKEG-----------------------
-LGL--SYDEMQAIFKEWN----D-TELNSYLVEITADILGYRDE--DGEPLLE----KI
LDTAGQKGTGK--WTGINALDLGIPLTLITESVFARCL----SAIKDQRVEAEALFGKTI
QPIDGDKKEWVDALRQALLASKIISYAQG---FMLIREA-SEENNWSLNYGNVALMWRGG
CIIRSAFLGNIRDAYEATPDIKFLGTDPYFKDILVDSLPAWRKVAAKAMEVGLPMPTMTS
ALTFLDGYTTGRLPANMIQAQRDYFGAHTYERLDQPRGQFFHTNWTGTGGDTASTTYDV
>NC_009725.1|c7|2354228-2355637|-|YP_001421809.1|6-phosphogluconate_dehydrogenase
-----------------------------MSKQQIGVIGLAVMGKNLALNIE-SRGFSVS
VYNRSSSKTEEFLEE-AK-G--KNVVGTYSIEEFVQSLETPRKILLMVKAGTATDATI--
--QSLLPH-LEKDDILIDGGNTYYKDTQRRNK-ELA-ESG-IHFIGTGVSG--GEEGALK
G----PSIMPGGQKEAHE-LVKPILEAIS----AK--------------VDGEACTTYI-
--GP-DGAGHYVKMVHNGIEYGDMQLISESYFILKQV-----------------------
-LGL--SAEELHEVFAEWN----K-GELDSYLIE-ITADIFTKKDEETGKPLVD----VI
LDKAGQKGTGK--WTSQSALDLGVPLPIITESVFARFI---SAMKEERVKASSLLSGPDV
KPVTENKEELIEAVRKALFMSKICSYAQG---FAQMKAA-SEEYNWDLKYGEIAMIFRGG
CIIRAAFLQKIKDAYDREPELDNLLLDSYFKNIAESYQGALRQVISLAVAQGVPVPSFSS
ALAYYDSYRTAVLPANLIQAQRDYFGAHTYERTDKEGIFHTEWMK--------------
>AM778942.1|c1|57835-59262|+|CAO90629.1|
-----------------------------MTKRTFGVIGLAVMGENLALNVE-SRGFPIA
VYNRTASKTKEFMETRAV-G--KDVKAAYSLEEFVQILERPRKILVMVKAGPPVDAVI--
--EQLKPL-LEEGDMIIDGGNSLYEDTERRTR-DLE-STTKLGFVGMGVSG--GEEGALH
G----PSLMPGGTEFAYR-ELEPILTKIA----AQ--------------VDDGPCVTYV-
--GS-GGAGHYVKMVHNGIEYGDMQLIAEAYDVLKNG-----------------------
-LGL--SNQQLQETFAEWN----RTDELNSYLIE-ITADIFKCVDPETGHHLVD----LI
LDSAGQKGTGR--WTVLSSLELGVPIPTIYAAVNARVM----SAYKDERVAAAKELPGPG
ETYPGDAALFVDKVRDALYCSKMCSYAQG---MALIAKA-SQEFNYNISLPESARIWKGG
CIIRASFLDKIRKAFAENPGLPNLLLAPEFKQSILDRQEAWREVLVLANKLGIPVPAFSS
SLDYFDSYRRANLPQNLTQAQRDYFGAHTYERTDKPRGEFFHTEWMTES----------
>NC_010546.1|c4|3882816-3884321|-|YP_001805160.1|6-phosphogluconate_dehydrogenase
-MFPRHTSTVKQDQSFLDQTTRRVGRNHYMTKRTFGVIGLAVMGENLALNVE-SRGFPIA
VYNRTASKTEEFMKTRAQ-GKDVK--AAYSLEEFVQILERPRKILVMVKAGAPVDYVI--
--EDLKPL-LEEGDMIIDGGNSLYEDTERRTK-DLE-STG-LGFVGMGVSG--GEEGALN
G----PSLMPGGTKAAYE-ELEPILTKIA----AQ--------------VDDGPCVTFV-
--GP-GGAGHYVKMVHNGIEYGDMQLIAEAYDIMKNA-----------------------
-MGL--SNQELHEVFKEWN----TTDELNSFLIE-ITADIFKYVDPDSNKHLVD----LI
LDSAGQKGTGR--WTVVSSLELGVPIPTMYAAVNARVM----SSYKEERKAASQQLTGPE
IKFDGDKKAFINKVRDALYCSKMCSYAQG---MALIAKASAEYYNNQVSLPESARIWKGG
CIIRAGFLDKIKKAFVDNPNLPNLLLAPEFKQTILDRQDAWREVLILANQVGIAVPAFSS
SLDYFDSYRRADLPQNLTQAQRDYFGAHTYERVDKPRGESFHTEWAA------------
>NZ_AAXW01000003.1|c1|204879-206300|-|ZP_01727589.1|6-phosphogluconate_dehydrogenase
-----------------------------MTKRTFGVIGLAVMGENLALNVE-SRGFPIA
VYNRTASKTEEFMKTRAQ-GKDVK--AAYSLEEFVQILERPRKILVMVKAGAPVDYVI--
--EDLKPL-LEEGDMIIDGGNSLYEDTERRTK-DLE-STG-LGFVGMGVSG--GEEGALN
G----PSLMPGGTKAAYE-ELEPILTKIA----AQ--------------VDDGPCVTFV-
--GP-GGAGHYVKMVHNGIEYGDMQLIAEAYDIMKNA-----------------------
-LGL--SNQELHEVFKEWN----TTDELNSFLIE-ITADIFKYIDPDSNKHLVD----LI
LDSAGQKGTGR--WTVVSSLELGVPIPTMYAAVNARVM----SSYKEERKAASQQLTGPE
IKFDGDKKAFINKVRDALYCSKMCSYAQG---MALIAKASAEYYNNQVSLPESARIWKGG
CIIRAGFLDKIKKAFVDNPNLPNLLLAPEFKQTILDRQEAWREVLILANKVGIAVPAFSS
SLDYFDSYRRADLPQNLTQAQRDYFGAHTYERVDKPKGESFHTEWAA------------
>NZ_AAWV02000001.1|c1|1066084-1066992|+|ZP_04431146.1|6-phosphogluconate_dehydrogenase,
--------------------------------MEIGIVGLGKMGLNLSLNML-DHQVDVK
AYDTSRDATAQLSS---L-D--SRAKCFPSLEALVQNLEVPRKVWVMVPSGEPTNETI--
--HKLSNL-LSAGDIVIDGGNSHYTDSCRHYT-LLQ-NKG-IHFLDVGTSG--GISGARN
G----ACLMIGGDKPVFD-QLEPLFEKIS----EK------------------DGYLYT-
--GK-PGSGHFLKMVHNGIEYGMMEALAEGFEILEKS-----------------------
--PYDYDN---QAVAKVWN----NGSVIRSWLVELLEDAF-------SKDAHLD----EI
SGVMASSGEGK--WTVETALDLQASIPVIALSLMNRYR----------------------
--------------------------SLEKDTFTGKVVA---------------------
------------------------------------------------------------
-------------------ALRNEFGGHAVTRSGQ------------------------
>NZ_CM000913.1|c7|3428540-3429415|+|ZP_06772385.1|6-phosphogluconate_dehydrogenase,
--------------------------------MQLGLVGLGKMGGNMRERIR-RAGHTVI
GYDRNPDIS-----------------DVHSLQELVDSLEGPRVVWVMVPAGAATQSTI--
--DELAEL-LSPGDIVVDGGNSRWTEDERHAV-ELG-IKG-IGFVDCGVSG--GVWGLEN
G----YALMYGGAPEHVA-QVQPVFDALK----PS----------------GPYGSVHA-
--GK-VGAGHFAKMVHNGIEYAMMQAYAEGWELLEKV-----------------------
--DSVTDV---REVFRSWQ----EGTVIRSWLLDLAVNAL-------DEDEHLD----KL
RGYAEDSGEGR--WTVEAAIDNAVPLPAITASLFARFA----------------------
--------------------------SRQDDSPQMKMIA---------------------
------------------------------------------------------------
-------------------ALRNQFGGHAVETK--------------------------
>NC_008596.1|c1|1721-2614|+|YP_884425.1|6-phosphogluconate_dehydrogenase-like_protein
--------------------------------MQLGLIGLGKMGFNMRERLR-EAGHEVI
GYDPRPEVS-----------------DVANLEELAGALSAPRVVWVMVPSGTITHSTIVE
-LAGV----LSPGDLVIDGGNSRYTEDGPHAE-LLG-EKG-ISFIDAGVSG--GIWGLTE
G----YGLMVGGSDDDVA-RAMPIFDALR----PP--------------GDVADGFVHA-
--GP-VGAGHYAKMVHNGIEYGLMHAYAEGYELLAAE-----------------------
--ELIKDP---QAVIQAWS----NGTVVRSWLQSLLAKAL-------KEDPGFA----EI
SGYTEDSGEGR--WTVEEAIAHRVPMPVIAASLFARFA----------------------
--------------------------SRQEDSPTMKAVS---------------------
------------------------------------------------------------
-------------------ALRNQFGGHAVKRISESG----------------------
>NC_010628.1|c10|4108447-4109469|+|YP_001866686.1|6-phosphogluconate_dehydrogenase-like_protein
--------------------------------MELAMIGLGRMGANMAQRLM-RAGHHVV
GYVRRTEKLSAMVN---E-GVIAA--GASSIADLVSKLSKPRTVWLMVPAASVDETI---
--ETLIPL-LEPDDIIIDGGNSYYHDDIRRAA-TLK-DRG-IHYVDCGTSG--GVWGLER
G----YCLMIGGEQVAIK-RLDPIFATLA----PGVGEIDRTPGREKAGGTAEQGYLHC-
--GP-IGAGHFVKMVHNGIEYGVMAAYAEGLNILHHA-NIGNNQREIDAETTPLRNPEHY
QYDF--NL---GDIAEVWR----RGSVIASWLLDLTAIAL-------LESPNLE----RF
GGRVSDSGEGR--WSAIAAIDESVPTPVLSAALFARFS----------------------
--------------------------SRGEADFADKLLS---------------------
------------------------------------------------------------
-------------------AMRYQFGGHYEKANS-------------------------
>NZ_ABIN01000060.1|c1|3027-4049|-|ZP_05224689.1|6-phosphogluconate_dehydrogenase-like_protein
--------------------------------MQLGMIGLGRMGANIVRRVV-AGGHECV
VYDHNPDAVEAMAG---EDK--TT--GVSSLQELAEKMTAPRVVWVMVPAGTITTGVI--
--DELAET-LESGDIVIDGGNSYYRDDISHAK-TLS-EKG-IHFLDCGTSG--GVWGRER
G----YCLMVGGDDEAFA-RAEPIFATVA----PGVDAAPRTPGRDGEVATSEQGYLHC-
--GP-AGAGHFVKMVHNGIEYGMMASLAEGLNILRNA-DIGKHVQEGDAETAPLSNPEFY
QYDF--DI---PEVAEVWR----RGSVIGSWLLDLTAIAL-------HESPELK----EF
SGRVSDSGEGR--WTSIAAIDEGVPSPVLTTALQSRFA----------------------
--------------------------SRSLDDFANKALS---------------------
------------------------------------------------------------
-------------------AMRKQFGGHAEKPAN-------------------------
>NZ_ADDL01000060.1|c1|14992-16011|-|ZP_06239787.1|6-phosphogluconate_dehydrogenase,
--------------------------------MQLGMIGLGRMGANLVRRLQ-RAGHECV
VYDVNKDAVAALAA---E-G--AT--GTTTLEEFAAALSTPRAAWVMVPAGLTGDTVF--
---KLADL-FEPGDIIIDGGNSYYRDDVDRAK-ALH-AKG-LHYVDVGTSG--GVFGLER
G----FCLMIGGEPEVVS-HLEPLFATIA----PGIGTAERTPGRSGEPTPAEQGYLHC-
--GP-PGAGHFVKMVHNGIEYGMMAAFAEGLGVLNKANIGKALAGEHDAETSPLTHPEYY
QYDL--DL---PAITEVWR----RGSVVASWLLDLTAAAL-------VEDPELA----QF
GGRVSDSGEGR--WTVLAAVEEGVPAHVLTASLYERFS----------------------
--------------------------SRGEALYSDKILS---------------------
------------------------------------------------------------
-------------------AMRKQFGGHSEKPAS-------------------------
>NC_009921.1|c19|6801545-6802567|+|YP_001509864.1|6-phosphogluconate_dehydrogenase-like_protein
--------------------------------MQLGMIGLGRMGANLVRRLM-RDGHECV
VYDVNPETVKSLAA---E-G--AV--GVNSLADFAAALSTPRAAWVMVPAGLTGQTVF--
---ELAEH-FEAGDIIIDGGNSYYRDDVDRAA-KLA-ERG-LHYVDVGTSG--GVFGLER
G----YCLMIGGEPEVAA-RLEPLFETIA----PGVDTAPRTPGRTGEIAQAEKGYLYC-
--GP-NGAGHFVKMIHNGIEYGMMAAFAEGMGILEKAGIGRSEAALHDAETAPLAHPEYY
QYDF--DI---ASVAEVWR----RGSVVSSWLLDLTATAL-------AEDPRLS----EF
GGRVSDSGEGR--WTVLAAVEEGVPAHVLTASLYERFS----------------------
--------------------------SRGESLFADKLLS---------------------
------------------------------------------------------------
-------------------AMRKQFGGHAEKKAEG------------------------
>NC_007777.1|c3|1099680-1100702|-|YP_480049.1|6-phosphogluconate_dehydrogenase-like_protein
------------------------------MKMQLGMIGLGRMGANLVRRLI-RGGHECV
VYDVNPEAVKALAA---E-G--AT--ETRSLAEFAAALRPPRAAWIMVPAGLTGETV---
--SALAEH-FAPDDVIIDGGNSYYRDDILRAA-SLV-ERG-IHYVDVGTSG--GVFGLER
G----FCLMIGGEPGVVA-RLEPLFETIA----PGVGTIPRTPGRTGEITQAEKGYLYC-
--GP-NGAGHFVKMVHNGIEYGMMAAFAEGFAVLDKA-NIGTTSAEHNAETAPLGNPEYY
QYDL--DT---TAIAEVWR----RGSVVSSWLLDLTAAAL-------QEDPGLT----EF
SGRVSDSGEGR--WTVLAAVEEGVPAHVLTASLYERFS----------------------
--------------------------SRGEGLFADKLLS---------------------
------------------------------------------------------------
-------------------AMRKQFGGHAEKPAG-------------------------
>NC_008278.1|c5|1677855-1678880|-|YP_711812.1|6-phosphogluconate_dehydrogenase-like_protein
--------------------------------MQLGMVGLGRMGANLVRRLI-RDGHECV
VYDVNAEAIKALEA---E-G--AT--GAGTLAEFAAALRPPRTAWIMVPAGLTGQTV---
--DAVAEH-FAPDDVIIDGGNSYYRDDIHKAA-ELA-TKG-IHYVDVGTSG--GVFGLER
G----YCLMIGGEPAVVA-RLEPLFETIA----PGVGAVPRTPGRAGEPVQAEKGYLYC-
--GP-NGAGHFVKMVHNGIEYGMMAAFAEGLAILDKA-NIGREALEHNAETAPLGDPQYY
QYDF--DT---AAIAEVWR----RGSVVSSWLLDLTATAL-------QEDPELA----EF
SGRVSDSGEGR--WTVLAAVEEGVPAHVLTASLYERFS----------------------
--------------------------SRGEGLFADKLLS---------------------
------------------------------------------------------------
-------------------AMRKQFGGHAEQHAPKAG----------------------
>EU240558.1|c1|59338-60198|+|ABY83183.1|Azi45
------------------------------------MIGLGPMGQAMTRTLL-TAGHPVT
VWNRTAGRADGVVT---D-G--AT--LAATPSEAVEASDL---VILSLTDYQAMYDIL--
---GSATA-SLAGRTLVNLSSDTPDRSREAAT-WAA-GHD-ATFLTGGVMVPAPMVGTEA
A-----HVYYSGRDQVME-RHLAALTLLG----TP---------------------KYL-
--GEDPGLAQMMYQAQLAVFLTTLSGLMHATAMLGTA-----------------------
--GM--KA--KEALPELLS----SADSIGDILRAGEENPG-----TALDAGEHP-GDLST
VTMMGATSDHI--VETSTSLGLDLALPLAVQAHYRRAI----------------------
--------------------------ENG---HGSDNWT---------------------
------------------------------------------------------------
-------------------RIIDSIRGPR------------------------------
>AB254080.1|c1|184113-185042|-|BAE95580.1|putative_dehydrogenase
-------------MPDNPSTKGRMMRNQQAEHTPVTVIGLGLMGQALAGAFL-GAGHPTT
VWNRTAAKAEPLVA---R-G--AK--SAGSVAEAVAASPL---VVVCVSDYDAVHALL--
--DPLDGT-ALQGRTLVNLTSGTSAQARERAA-WAD-GRG-ADYLDGAILA--GPAAIGT
A---DAVVLLSGPRSAFD-PHASALGGLG----AG--------------------TTYL-
--GADHGLASLYDAAGLVMMWSILNGFLQGAALLGTA-----------------------
--GV--DA---TTFAPFITQ---GIGTVADWLPGYARQ---------IDDGAYP-ADDAA
IDTHLATMEHL--IHESEFLGVNAELPRFIKALADRAV----------------------
--------------------------ADG---HGGSGYP---------------------
------------------------------------------------------------
-------------------ALIEQFRTHSGK----------------------------
>NC_013729.1|c9|6801130-6802017|+|YP_003384148.1|6-phosphogluconate_dehydrogenase_NAD-binding
--------------------------MTDHSRTPVTVLGLGPMGQALAAAFL-AAEHPTT
VWNRTPGKGDQLAA---Q-G--AT--VASTAAEAAAASGL---IVVCVLDYDAVEQILAA
-AEPVLAG-----RTVVNLTADSPDRARQTAQ-WAA-ERG-IQYLDGAIMTPTETIGGPE
A-----VVLYSGPKDLYA-GHAPALAALG----GT--------------------QSHL-
--GEDPGRAAAHDVALLGIFWTALTGIMHAFALAKAE-----------------------
--NI--AA---RDLAGFAR----GITDLLSPSIDGFAANI---------DAGEH-PG-TT
TNLLSAAAGIAHIVHASEQHGIDAGLLRAAHALTRQAI----------------------
--------------------------ADG---HGTDEFT---------------------
------------------------------------------------------------
-------------------RLTDTLLRHATR----------------------------
>NZ_ADFC01000003.1|c2|248668-249585|-|ZP_06276878.1|6-phosphogluconate_dehydrogenase_NAD-binding
------------MIDSGLGASLIGMAPNTVEKTPVTLLGLGAMGTALARTWL-AAGHPLT
VWNRTSARATALAA---E-G--AR--AADTAADAVAANTL---IVVCLLDDTSLEQVLAG
-------T-DLAGRDLVNLTTGTPAQARARAE-WAR-ERG-ARYLDGGIMAVPPMIGVPE
A---GGYVFYSGSRELFEAHRETLATPAG--------------------------TTYV-
--GEDAGHAALHDVALLSAMYGMFAGAAHAFALIRKE-----------------------
--DI--DP---ASLAPLLA----D------WLVA--MAPSVHQTADQLRSGDYT-KG-VV
SNLAMQVAGAPTFLSTAEQQGVSPELLSPYFELMRRRL----------------------
--------------------------AEG---SGEEDLT---------------------
------------------------------------------------------------
-------------------GVIDLLVR--------------------------------
>NC_010572.1|c25|7900361-7901242|+|YP_001828124.1|putative_dehydrogenase
------------------------MAPNTVEKTPVTLLGLGAMGTALARTWL-AAGHPLT
VWNRTSARATALAA---E-G--AR--VADTAADAVAANTL---TVVCLLDDTSLEQVLAG
-------T-DLAGRDLVNLTTGTPAQARARAE-WAR-ERG-ARYLDGGIMAVPPMIGVPE
A---GGYVFYSGSRELFEAHRETLATPAG--------------------------TTYV-
--GEDAGHAALHDVALLSAMYGMFAGAAHAFALIRKE-----------------------
--DI--DP---ASLAPLLA----D------WLV--AMAPSVHQTADQLRSGDYT-KG-VV
SSLAMQVAGAPTFLSTAEQQGVSPELLSPYFELMRRRL----------------------
--------------------------AEG---SGEEDLT---------------------
------------------------------------------------------------
-------------------GVIDLLVR--------------------------------
>NC_008312.1|c3|4619069-4620061|-|YP_722600.1|6-phosphogluconate_dehydrogenase,_NAD-binding
--------MYTGLNINMSPSKNTSETNPPLNYPTLGIIGCGNIGGRQAANFI-AQGYPVY
VYDINLDRMTELES---L-G--AH--ITHSCAELATYSDV---IFTSLPTPADVVRAVLE
GDGNLSQG-LRSRSIYIDITTNSPETIFKLSK-AME-ELG-VEMLDAPFND--CPEGAKS
DGGMGLAVMASGSRKTFE-RVEPILQLMA----DR--------------------VIYC-
--GT-LGNGTRCKLIHNAVNAVAVQAVTEGITLGLAQ-----------------------
--GI--PL---ETIWDALR----F-GAFGQNAGD-IHGLPHYWFSRRCDDLSQH-PD-FT
VKLLHKDLQLA--LEMASQQNISVPQFSLTVKDYEEAV----------------------
--------------------------RRG---FSDYSTT---------------------
------------------------------------------------------------
-------------------KVRCLQEEQARVMAKTT-----------------------
>NC_013161.1|c4|3110127-3111020|+|YP_003138756.1|6-phosphogluconate_dehydrogenase_NAD-binding
----------------------------MTEKMNIGVLGTGLMGKPLAQRLL-QANLSVT
VYNRTFSQVVELES---M-G--AN--LAKTPLEAIQLSNV---LILMLTDANAIREVILS
-TESASAL---QNRTVIQMGTIAPDESRTIQQ-EVQ-ARG-GDYLEAPVLG--SIPEAKA
G---KLLVMVGARKSQFE-EWKGLLQHFG----EQ--------------------PQHI-
--GE-VGTASALKLALNQLIAALTSGFALSLGLIERQ-----------------------
--GV--DV---DKFMAILR----E-SALYAPTFDKKLDR--------MKQRNFDNPN-FP
TKHLLKDVDLF--LSQAEENGLNTEGLKGVRGLIQKTI----------------------
--------------------------ALG---LSDSDYS---------------------
------------------------------------------------------------
-------------------ALFSAIHQEEHDNIIH------------------------
>NC_011726.1|c5|3187212-3188105|-|YP_002373182.1|6-phosphogluconate_dehydrogenase_NAD-binding
----------------------------MTEKMNIGVLGTGLMGKPLAQRLL-QANLSVT
VYNRTFSQVVELQS---M-G--AN--LAKTPLEAIQLSNV---LILMLTDANAIREVILS
-TESASAL---QNRTVIQMGTIAPDESRTIQQ-EVQ-ARG-GDYLEAPVLG--SIPEAKA
G---TLLVMVGARKSQFE-EWKGLLQHFG----EQ--------------------PQHI-
--GE-VGTASALKLALNQLIAALTSGFALSLGLIERQ-----------------------
--GV--DV---DKFMAILR----E-SALYAPTFDKKLDR--------MKQRNFDNPN-FP
TKHLLKDVDLF--LSQAEENGLNTQGLKGVRGLIQKTI----------------------
--------------------------ALG---LSDSDYS---------------------
------------------------------------------------------------
-------------------ALFSAIHQEEHDNIIH------------------------
>NZ_DS999213.1|c3|1410034-1410984|-|ZP_05099703.1|2-hydroxy-3-oxopropionate_reductase,_putative
--------------------------------MKVGFIGLGNVGGKLSGSLL-RNGIDLS
VHDLNADFVAAKVA---M-G--AK--DGKSPADLMQNCDV---VITCLPSPAASAAVL--
--DKMMPH-VGRGKIWMEMSTTDAAEVERLGR-TVI-DAG-GAAVDCPVSG--GCHRADT
G---NISIFAGCDRTSFD-RILPLLTIMG----RR--------------------VLHT-
--GD-LGSASVLKVMTNYLATVNLISVCEAMTVMKAA-----------------------
--GM--DL---ATTFQAIS----M-SSGTSFVHETESQLIL------SGSRDVN----FT
MDLVQKDIGLF--QKLADEFLVPLEVSPLIIDIMTDGQ----------------------
--------------------------KR----YGERAQS---------------------
------------------------------------------------------------
-----DRIIERLEDATGLKILADGFPQELVDDEPEERGYEVAARSSL------------
>NZ_ABFY02000013.1|c1|50241-51164|+|ZP_02431078.1|hypothetical_protein
--------------------MNNNEHKERKRKMKVGFIGLGIMGRPMAKNMV-KAGVDLM
VADLNKEAVADVVA---A-G--AK---EGTYAQIGAECGV---VFTIVPNGDIVKSILFD
-EGGVAST-LKAGSIVCDMSSVTPVESKECYT-RLK-EKG-VGFIDAPVSG--GEPGAVA
G---TLAIMAGGEEKDFQ-ALKEYFDILG----SS--------------------ALLI-
--GG-SGSGSVTKLANQIIVNNTIAVVSEAFVLAAKA-----------------------
--GA--DP---QKVYEAIR----G-GLAGSAVLD-AKIPM-------IVERNFK-PG-GP
IRINHKDIKNV--VNTAHAVDVPIPYTAQLYEILQTLK----------------------
--------------------------IHG---HMEDDHA---------------------
------------------------------------------------------------
-------------------GIVQYFEKLADVEVKKFD----------------------
>NC_012490.1|c10|3672570-3673514|+|YP_002766831.1|oxidoreductase
--------------------MTESAPKASASKTRLGYIGLGNMGAPMAQRLL-DWPGGLM
VCDARAEALEPFTT---A-G--AS--AASTPADVAAQASI---ISVTVLDDAQVREVVCG
-PHGILST-AQPGTVVAIHSTISDTTAVELAD-ICQ-QRG-VLLVDAPISG--GAGGAAQ
G---RLAVMIGGSDEAFE-AVREPFGSWA----EL--------------------VVHA-
--GD-VGAGTRMKLARNLLHFVSFTATTEAARLAEAA-----------------------
--GL--DL---RTLGKVVRHTDAITGGAGAIMLRDTTAPV------SEDDPWFS-ILRHV
RNLGEKDLALA--IDLGDRLNLDLPLAHLALAGLGAGL----------------------
--------------------------GVG---NDSEDRP---------------------
------------------------------------------------------------
-------------------AEPSTASSASTTREHA------------------------
>NZ_ACNO01000066.1|c1|16200-17135|-|ZP_04386551.1|hypothetical_oxidoreductase
--------------------MTESAPKASASKTRLGYIGLGNMGAPMAQRLL-DWPGGLV
VCDARAEALEPFTA---A-G--AS--AASTPADVAAQASI---ISVTVLDDAQVREVVCG
-PHGILST-AQPGTVVAIHSTISDTTAVELAD-ICQ-QRG-VLLVDAPISG--GAGGAAQ
G---RLAVMIGGSDEAFG-AVREPFGSWA----EL--------------------VVHA-
--GD-VGAGTRMKLARNLLHFVSFTATTEAARLAEAA-----------------------
--GL--DL---RTLGKVVRHTDAITGGAGAIMLRDTTAPV------SEDDPWFS-ILRHV
RNLGEKDLALA--IDLGDRLNLDLPLAHLALAGLGAGL----------------------
--------------------------GVG---NDSEDRP---------------------
------------------------------------------------------------
-------------------AEPSTASTTREHA---------------------------
>NZ_DS995281.1|c1|349032-349931|-|ZP_05078363.1|hypothetical_oxidoreductase_YihU
-------------------MTTDAISPPPRPALRVAVLGAGLMGAPMARNIA-AAGCQVS
VWNRTPDKALSLAA---P-N--IT--PAADPAGAALHADV---IVTMLKDASAIADVMSA
-LPDADSV-PAAPVCWLQMSTVGPADMPGLET-LAA-RKG-LTLIDAPVLG--TRQPAEA
G---QLLVLAAGPDSTKE-AVQPVLDAVG----KA--------------------TRWL-
--DTAPGMATRLKLALNSWVFALTHGAAESLALARGL-----------------------
--GL--DP---QLVADTLR----G-GPLDTPFFQMKAQA--------MASGNFT-PA-FT
IDNAVKDSALI--VDAALEAGVRADLAEAGLTRYRRAQ----------------------
--------------------------AQG---HGSADMA---------------------
------------------------------------------------------------
-------------------ATYLASQ---------------------------------
>NC_003155.4|c8|1885125-1886015|-|NP_822718.1|dehydrogenase
----------------------------MTDTLTVSVLGTGIMGAAMARNLA-RAGHTVR
AWNRTRAKAEPLAA---D-G--AH--IADTPAEAVEGADV---VLTMLHDGDAVLGVM--
--RQAAPA-LRPGTAWIQSTTAGLDALTGLAD-FAR-EHR-LAFFDAPVLG--TRQPAEA
G---QLVVLAAGPTESRE-TVTPVFDAVG----SR--------------------TLWTG
EDGA-AGSATRLKLVANSWVIAATNATGEVLALAKAL-----------------------
--GV--DP---QNFFDAIA----G-GPLDMGYLH-AKADL-------VLNNGLT-PASFA
VSTAEKDARLI--VQAGQEHGVRLDGAEASAERLHRAA----------------------
--------------------------AQG---HADEDMA---------------------
------------------------------------------------------------
-------------------AVYYASFDETRTP---------------------------
>NZ_ACMW01000053.1|c1|6248-7138|+|ZP_04157044.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---D-G--GI--IGLSIANLAETCDL---IFTSLPSPRAVEAVYFG
-EEGLIEN-SHPNVVLIDTSTVAPQLNKRLAE-AAN-DKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KGLPVMEVLG----AN--------------------VFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---EKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNLYDEAG----------------------
--------------------------KAG---YGEKDMA---------------------
------------------------------------------------------------
-------------------ALYKKISEQVISSHE-------------------------
>NZ_ACMV01000136.1|c1|29861-30751|+|ZP_04162794.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---D-G--GI--IGLSIANLAETCDL---IFTSLPSPRAVKAVYFG
-EEGLIEN-SHPNVVLIDTSTVAPQLNKRLAE-AAN-DKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KGLPVMEVLG----AN--------------------VFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---EKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNLYDEAG----------------------
--------------------------KAG---YGEKDMA---------------------
------------------------------------------------------------
-------------------ALYKKISEQVISSHE-------------------------
>NZ_ACNF01000058.1|c1|65131-66021|+|ZP_04102079.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLA-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-EKK-VNFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNFKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACNK01000049.1|c1|55349-56239|+|ZP_04071951.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSILKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKKVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNFKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPISEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_011772.1|c4|2177751-2178641|+|YP_002445716.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSILKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-VAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNFKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACNB01000078.1|c1|7923-8813|+|ZP_04126416.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSILKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNFKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACNC01000080.1|c1|16381-17271|+|ZP_04120324.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-ERK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKDVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ABDA02000007.1|c2|285716-286606|-|ZP_03232489.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNIVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPEKYE-PG-FT
MNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACLV01000044.1|c1|139594-140484|+|ZP_04306062.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNIVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGLKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACMM01000313.1|c1|4978-5868|+|ZP_04215618.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNIVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACLT01000052.1|c1|8001-8891|+|ZP_04317415.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-ERK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACND01000063.1|c1|8030-8920|+|ZP_04114747.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACMA01000044.1|c1|8005-8895|+|ZP_04278770.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSGYTVY
GVDLNKEAEASFEK---E-G--GI--IGLSISKLAETCDV---VFTSLPSPRAVEAVYFG
-AEGLFEN-GHSNVVFIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKDVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACLY01000042.1|c1|21218-22108|+|ZP_04289288.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKEVEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYD-KTESIMEVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--NL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQFISNQK-------------------------
>NZ_ACMR01000095.1|c1|1909-2799|+|ZP_04186122.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKEAEASFES---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVALIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEKIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--DM--DL---DKMFDILN----V-SYGQSRIYERNYNSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACLW01000055.1|c1|20531-21421|+|ZP_04300587.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKEAEASFEN---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKR-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IATENYD-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_003909.8|c1|2271769-2272659|+|NP_978691.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKNAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IAPENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYDEAS----------------------
--------------------------QAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACLS01000062.1|c1|92839-93729|+|ZP_04323310.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKNAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKKVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_011658.1|c1|2287268-2288158|+|YP_002338407.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKNAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_008600.1|c2|2244666-2245556|+|YP_894910.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KAESIMAVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACLZ01000032.1|c1|84346-85236|+|ZP_04284033.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GLDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSHVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ABDL02000001.1|c1|528175-529065|-|ZP_03234778.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGGLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_011969.1|c2|2242658-2243548|+|YP_002529997.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-EEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_011773.1|c2|2251777-2252667|+|YP_002451322.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEVSFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKS-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ABCZ02000004.1|c1|157689-158579|-|ZP_03101255.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKS-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_ACNE01000047.1|c1|18919-19809|+|ZP_04108301.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASEDYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NZ_AAEK01000006.1|c1|67294-68184|-|ZP_00236749.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSSYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>NC_012581.1|c1|2050373-2051263|-|YP_002814845.1|putative_2-hydroxy-3-oxopropionate_reductase
-------------------------------MKKIGFIGLGNMGLPMSKNLV-KSNYTVY
GVDLNKDAEASFEK---E-G--GI--IGLSISKLAETCDV---IFTSLPSPRAVEAVYFG
-QEGLFEN-SHSNVVLIDTSTVSPQLNKQLEE-AAK-EKK-VDFLAAPVSG--GVIGAEN
R---TLTFMVGGSKEVYE-KTESIMGVLG----AN--------------------IFHV-
--SEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKN-----------------------
--NM--DL---DKMFDILN----V-SYGQSRIYERNYKSF-------IASENYE-PG-FT
VNLLKKDLGFA--VDLAKESELHLPVSEMLLNVYEEAS----------------------
--------------------------EAG---YGENDMA---------------------
------------------------------------------------------------
-------------------ALYKKVSEQLISNQK-------------------------
>DS985220.1|c1|1524510-1525686|-|EEY20205.1|ketose-bisphosphate_aldolase_class-II_family
------------------------------------MIGLGAMGQGMASSMI-RGGFAVH
GYDVYEPAIQKFVS---G-G--GKASAATSPADAARGAEV---LVLMVQNATQATDALFG
-SGDAAAA-LPDDAIVILSSTVPPSFVRSLEKRLAGLGRG-ITLLDAPVSG--GVVRAAN
G---NLTIICSGEESTISKANGVLLSMTG----LA--------------------TNLCQ
VKGG-VGAASSVKLINQLLAGVHIAAAAEAMAFAARL-----------------------
--GL--DT---RQIFELLK----N-AAAWSWMFE-NRVPQ-------MLEADWT-PH-SA
LAIFVKDLGIV--LDETKRLMYFAPMSSAAHTLYLAGA----------------------
--------------------------AKG---WSKEADA---------------------
------------------------------------GVVRWWEGAGVSVSGSAGRPEPHT
TNEALRAAAQPLPAKETIEALPAEFPYDVLESTKKPCRASSRGSREASSS---------
>NC_009720.1|c3|1179742-1180734|-|YP_001415935.1|3-hydroxyisobutyrate_dehydrogenase
MPMPSQRSSLFEDQVMTEQFSPEVAISGATGTGGAAVIGLGSMGYGMAQSLK-RAGFDVA
GFDVNAAAVERFAA---E-G--GR--GASSPAEAARDADV---VVSVVVNAAQTETILFG
-ADGVAQT-LADGAVFLSSATMDPEIARTLAA-RLE-ATG-RLYLDAPISG--GAQRAAE
G---ALTILASGSPAAFA-KARPALDAMA----AK--------------------LYEL-
--GDAPGQGAAFKMINQLLAGVHIAAASEAVAFAARQ-----------------------
--GL--DI---AKVYEVIT----A-SAGNSWMFE-NRMPH-------VVDGDYT-PR-SA
VDIFVKDLGII--QDMARSAKFPVPVSAAALQMFLATS----------------------
--------------------------AAG---MGRDDDA---------------------
------------------------------------------------------------
-------------------SVARLYARITGTKLPGDPA---------------------
>NC_010086.1|c2|422837-423727|-|YP_001583476.1|3-hydroxyisobutyrate_dehydrogenase
------------------------------MSRNVGVIGLGAMGLGVARSLL-RAGFRVH
ACDVREAVLHAFAA---E-G--GI--ACATPAELGAQCDV---VVTLVVNAAQTETVLFG
-EHGAVAS-MKPGGVVIASATVAPDFAVSLGA-RIE-AAG-LQMLDAPVSG--GAARAAS
G---EMTMMTSGPAAAYA-ACEDVLAAMA----GK--------------------VYRL-
--GDTHGVGSKVKIINQLLAGVHIAAAAEAMALGLRE-----------------------
--GV--DP---DALYDVIT----H-SAGNSWMFE-NRVPH-------ILNGDYT-PL-SA
VDIFVKDLGLV--LDTARRSKFPLPLSAAAHQMFMSAS----------------------
--------------------------SAG---HGGEDDS---------------------
------------------------------------------------------------
-------------------AVIKTFPGITLPAAR-------------------------
>NZ_ACFD01000006.1|c1|96413-97303|-|ZP_03573325.1|3-hydroxyisobutyrate_dehydrogenase_family
------------------------------MSRNVGVIGLGAMGLGVARSLL-RAGFRVH
ACDVREAVLHAFAA---E-G--GI--ACATPAELGAQCDV---VVTLVVNAAQTETVLFG
-EHGAVAS-MKPGGVVIGSATVAPDFAVALGA-RIE-AAG-LQMLDAPVSG--GAARAAS
G---EMTMMTSGPAAAYA-ACEDVLAAMA----GK--------------------VYRL-
--GDTHGVGSKVKIINQLLAGVHIAAAAEAMALGLRE-----------------------
--GV--DP---DALYDVIT----H-SAGNSWMFE-NRVPH-------ILNGDYT-PL-SA
VDIFVKDLGLV--LDTARRSKFPLPLSATAHQMFMSAS----------------------
--------------------------SAG---HGGEDDS---------------------
------------------------------------------------------------
-------------------AVIKTFPGITLPPAR-------------------------
>NZ_ABIA02000005.1|c2|316329-317198|+|ZP_02166795.1|putative_dehydrogenase/reductase
-------------------------------MATVAFIGLGVMGYPMAGYLKTKGGHDVR
VYNRTTAKAEKWAA---EFG--GT--ACALPSEAATGADF---VFTCVGNDDDLRAVTLG
-ANGALDG-MKEGAILIDNTTASAEVARELAE-ACA-KKG-CGFLDAPVSG--GQAGAEN
G---VLTVMVGGDEATFA-KAQPVIDAYA----RM--------------------VGLM-
--GP-VGSGQLTKMINQICIAGLVQGLSEGIHFAKKA-----------------------
--GL--DI---EKVVEVIS----K-GAAGSWQME-NRHKT-------MNAGEYE-HG-FA
IDWMRKDLDIV--LNEAKRNGATLPVTALVDQFYADVQ----------------------
--------------------------AMG---GNRWDTS---------------------
------------------------------------------------------------
-------------------ALLARLEK--------------------------------
>NC_007925.1|c3|2260439-2261308|-|YP_531938.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MAKVAFLGLGVMGFPMAGHLVAKGGHEVT
VFNRTQAKANIWAE---KFA--GR--TAPTPREAAEGQDF---VMACVGNDDDLRSVTIG
-DDGAFAG-LDAGAIFVDHTTASAEVARELDA-EAT-KRG-FAFVDAPVSG--GQAGAEN
G---VLTVMCGGSAEAYA-RAEPVIAAYA----RM--------------------CKLM-
--GP-AGSGQLTKMVNQICIAGLVEGLSEGIHFAKKA-----------------------
--GL--DV---NAVIDTIS----K-GAAQSWQME-NRHKT-------MTEGKFD-FG-FA
VEWMRKDLAIC--LSEARRNGASLPVTALVDAFYAEVE----------------------
--------------------------KLG---GRRWDTS---------------------
------------------------------------------------------------
-------------------SLLARLER--------------------------------
>NC_003030.1|c2|3514815-3515693|+|NP_349934.1|3-hydroxyisobutyrate_dehydrogenase
---------------------------MINKNTKIGFIGTGVMGKGMIKNLL-KGGYTVH
VYNRTKEKALPLVE---I-G--AV--LETSIKELSQRCDV---IITMVGYPSDVEEVYFN
-DNGILNN-LKPQSYVVDMTTSKPSLAKKIYA-AAK-ERN-IFALDAPVSG--GDIGAAE
G---TLSIMVGGDKEAFD-ALMPIFELMG----KN--------------------IVLQ-
--GS-AGSGQHTKMCNQIAIASNIMGVCEALSYAKKS-----------------------
--GL--NA---ETVLKSIG----A-GGAASWQLS-AYAPR-------ILKGDFN-PG-FY
IKHFVKDMKIA--LEEADEMGLKTPALELSKKLYDKLI----------------------
--------------------------KEG---KEDLGTQ---------------------
------------------------------------------------------------
-------------------ALYHLYNED-------------------------------
>NC_011883.1|c1|1569759-1570664|+|YP_002479900.1|2-hydroxy-3-oxopropionate_reductase
----------------------------MAEKLRIGWIGTGVMGLSMAGHLQ-DAGHSLT
VYNRTRAKADPLLA---K-G--AQ--WADTPRQAAANADV---VFTIVGYPQDVESVILG
-EEGVLQG-LPSGGIVCDMSTSSPSLAERIAE-AAL-LQS-CLSLDAPVTG--GDVGARN
A---TLSIFVGGDKDGYE-RLESCFKSMG----KN--------------------ILHC-
--GG-PGFGQKAKLANQVAIAGVMFSVCESCLFAQEA-----------------------
--GL--DV---VQWLELVV----M-GAAGSKAMDTLGRR--------ILKNDFA-PG-FF
INHFIKDLGLC--LEECRRMQIVLPGIGLAEELYRSMQ----------------------
--------------------------ARGQGNLGTQALI---------------------
------------------------------------------------------------
------------------DCLASLSGKHWQQHSS-------------------------
>NC_012522.1|c8|2519391-2520290|+|YP_002779535.1|putative_hydroxyacid_oxidoreductase
------------------------------MTTTVGFVGLGNIGGRVVAHLV-KAGHDVA
VYDLNTASVDAAVA---L-G--AR--SVASPAEAATKAEA---LFLSLPTPAIVEGVV--
--AEVLQQ-RNQGLVIVDHSTIDPDTTRRLAQ-DAQ-AAG-ASFLDAPVSG--GVQGAEA
G---TLAVMLGGDEASVK-KVIPLIETYA----GN--------------------IFHV-
--GP-SGSGQAIKLANNQVTAANIVALGEGLSSAVAA-----------------------
--GV--DL---DTAVAVLT----K-SSANSNVLSNYFPKT-------LFTEERP-TG-FA
LDFMHKDLGLF--LDAAGKSELPTPITSLVRDLFSIGQ----------------------
--------------------------RDG---RGGKDFT---------------------
------------------------------------------------------------
-------------------SVVEFYEDFTGIRLQTKGNHQ-------------------
>NZ_CM000913.1|c17|6456743-6457654|+|ZP_06774956.1|3-hydroxyisobutyrate_dehydrogenase
------------------------MEERKMPDTTVAFIGLGTMGRPMAERLL-AAGHRLT
VHDRLTGATAALAA---A-G--AA--TAPSAREAASGAAV---VITMLPNGPHVREALTG
-PDGALAA-MRPGAVLVDMSTIDPSTSKEMAA-LAE-RHG-VRMLDAPVSG--SSAGAVE
G---TLTVMVGGDPGTLD-ELRPLLGELG----RT--------------------VVHC-
--GP-NGAGVSVKLANQIIAGASMAAVAESYALAQRL-----------------------
--GV--DP---RLLFDVVS----A-SSGDCWALR-TRPPVPGVLPTSPADDGFR-PG-FK
GALMCKDLDLA--LATAADWSVDLPVTMHARDLYARMS----------------------
--------------------------EEG---LGERDFS---------------------
------------------------------------------------------------
-------------------AVFALLSKQG------------------------------
>NC_008463.1|c7|4846783-4847679|+|YP_792542.1|putative_3-hydroxyisobutyrate_dehydrogenase
-------------------------------MKQIAFIGLGHMGAPMATNLL-KAGYLLN
VFDLVQSAVDGLVA---A-G--AG--AARSARDAVQGADV---VISMLPASQHVEGLYLD
-DDGLLAH-IAPGTLVLECSTIAPTSARKVHA-AAR-ERG-LAMLDAPVSG--GTAGAAA
G---TLTFMVGGDDEALE-KARPLFEAMG----RN--------------------IFHA-
--GP-DGAGQVAKVCNNQLLAVLMIGTAEAMALGVAN-----------------------
--GL--DA---KVLAEIMR----R-SSGGNWALE-VYNPWPGVMENAPASRDYS-GG-FM
AQLMAKDLGLA--QEAAQASASSTPMGSLALSLYRLLL----------------------
--------------------------KQG---YAERDFS---------------------
------------------------------------------------------------
-------------------VVQKLFDPTQGQ----------------------------
>NZ_GG704953.1|c1|68918-69808|-|ZP_06059137.1|3-hydroxyisobutyrate_dehydrogenase
--------------------------------MNIAFIGLGNMGGRMAHNLL-KAGIKVY
GYDLSEVAIQHFAE---A-G--GV--VCDSPQAAAKQADV---VITMLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAH-SKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADEQTFN-EVKPVLSHMG----KN--------------------IVHC-
--GE-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----S-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPILLGGMVQQLYQQMC----------------------
--------------------------MRG---NANLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>NZ_GG753605.1|c1|75091-75981|-|ZP_06693498.1|conserved_hypothetical_protein
--------------------------------MNIAFIGLGNMGGKMAHNLL-KAGLKVY
GYDLSEVAIQHFAE---A-G--GV--VCSSPQDAAKQADV---VITMLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAH-GKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADDQTFN-EVKPVLSHMG----KN--------------------IVHC-
--GD-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----T-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPVVLGGMVQQLYQQMC----------------------
--------------------------MRG---NANLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>NZ_GG704516.1|c1|15050-15940|+|ZP_05825497.1|3-hydroxyisobutyrate_dehydrogenase
--------------------------------MNIAFIGLGNMGGRMAQNLL-KAGLKVY
GYDLSEVAIQHFAE---A-G--GI--VCDSPQNAAKQADV---VITMLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAQ-SKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADDQTFN-EVKPVLSHMG----KN--------------------IVHC-
--GD-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----T-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPVVLGGMVQQLYQQMC----------------------
--------------------------MRG---NAHLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>NC_009085.1|c1|123404-124108|+|YP_001083192.1|3-hydroxyisobutyrate_dehydrogenase
------------------------------------------------------------
----------------------------------------------MLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAH-SKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADEQTFN-EVKPVLSHMG----KN--------------------IVHC-
--GD-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----T-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPVLLGGMVQQLYQQMC----------------------
--------------------------MRG---NAHLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>NC_010611.1|c1|146557-147447|+|YP_001844789.1|3-hydroxyisobutyrate_dehydrogenase
--------------------------------MNIAFIGLGNMGGRMAQNLL-KAGLKVY
GYDLSEVAIQHFAE---A-G--GV--VCDSPQDAAKQADV---VITMLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAH-SKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADEQTFN-ELKPVLSHMG----KN--------------------IVHC-
--GD-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----T-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPVLLGGMVQQLYQQMC----------------------
--------------------------MRG---NAHLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>NZ_GG704579.1|c1|68212-69102|-|ZP_05829849.1|3-hydroxyisobutyrate_dehydrogenase
--------------------------------MNIAFIGLGNMGGRMAQNLL-KAGLKVY
GYDLSEVAIQHFAE---A-G--GV--VCDSPQDAAKQADV---VITMLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAH-SKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADEQTFN-EVKPVLSHMG----KN--------------------IVHC-
--GD-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----T-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPVLLGGMVQQLYQQMC----------------------
--------------------------MRG---NAHLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>CP000521.1|c1|123218-124108|+|ABO10590.2|3-hydroxyisobutyrate_dehydrogenase
--------------------------------MNIAFIGLGNMGGRMAQNLL-KAGLKVY
GYDLSEIAIQHFAE---A-G--GV--VCDSPQDAAKQADV---VITMLPAAKHVKEVYLG
-ENGVLEV-LKAGSLCIDSSTIDPQTIKDIAA-VAH-SKN-IKICDAPVSG--GTIGAQA
G---TLTFMVGADEQTFN-EVKPVLSHMG----KN--------------------IVHC-
--GD-VGAGQIAKICNNLILGISMAAVAEGMALGVKL-----------------------
--GI--DP---QALAGVIN----T-SSGRCWSSD-VCNPWPHINENAPASRGYQ-DG-FA
TQLMLKDLGLA--VEAAGQVKQPVLLGGMVQQLYQQMC----------------------
--------------------------MRG---NAHLDFS---------------------
------------------------------------------------------------
-------------------SIIQQYLPQEA-----------------------------
>NW_002196564.1|c1|239602-240498|-|YP_002254778.1|3-hydroxyisobutyrate_dehydrogenase_protein
--------------------------------MNIAFIGLGNMGAPMAHNLL-KAGHALN
VFDLNAQAVQSLTD---A-G--AH--AAPSPKAAVTGVDC---VITMLPAAAHVRSVLTA
-DDGILAG-IPKGVPIIDSSTIDPDSAKAFAA-LAA-AHG-NVFVDAPVSG--GTGGAAA
G---TLTFMVGGSTAAFE-QVRPVLSAMG----KH--------------------LVHC-
--GA-TGAGQGAKICNNLVLGITMAGVAEAMSLGEAL-----------------------
--GI--DP---KVLGGIIN----T-STGRCWSSD-TYNPFPGVVETAPSSRGYT-GG-FG
TDLMLKDLGLA--GDAARSVRQPVYLGALAQQLYQAMS----------------------
--------------------------SKG---AGKLDFS---------------------
------------------------------------------------------------
-------------------AVIRLYRPEGAAQ---------------------------
>NW_002196568.1|c1|874636-875532|-|YP_002257485.1|3-hydroxyisobutyrate_dehydrogenase_protein
--------------------------------MNIAFIGLGNMGAPMAHNLL-KAGHALN
VFDLDAQAVQSLTD---A-G--AH--AAPSPKAAVTGVDC---VITMLPAAAHVRSVLTA
-NDGILAG-IPKGVPIIDSSTIDPDSAKAFAA-LAA-AHG-NVFVDAPVSG--GTGGAAA
G---TLTFMVGGSTAAFE-QVRPVLSAMG----KH--------------------LVHC-
--GA-TGAGQGAKICNNLVLGITMAGVAEAMSLGEAL-----------------------
--GI--DP---KVLGGIIN----T-STGRCWSSD-TYNPFPGVVETAPSSRGYT-GG-FG
TDLMLKDLGLA--GDAARSVRQPVYLGALAQQLYQAMS----------------------
--------------------------SKG---AGKLDFS---------------------
------------------------------------------------------------
-------------------AVIRLYRPEGAAQ---------------------------
>NC_003296.1|c2|825302-826198|-|NP_522210.1|3-hydroxyisobutyrate_dehydrogenase
--------------------------------MKIAFIGLGNMGAPMARNLL-KAGHALS
VFDLDARAVQSLVD---A-G--AS--AAPSPKAAATGADC---AITMLPAAAHVHSVLTA
-DDGILAG-IAKGVPIIDSSTIDPDSAKALAA-LAT-AHG-NPFVDAPVSG--GTGGAAA
G---TLTFMVGGGAAVFE-QVRPVLSAMG----KN--------------------LVHC-
--GE-AGAGQGAKICNNLVLGITMAGVAEAMSLGEAL-----------------------
--GI--DP---KVLGGIIN----T-STGRCWSSD-TYNPFPGVIETAPSSRGYT-GG-FG
TDLMLKDLGLA--GDAAKSVRQPVYLGALAQQLYQASS----------------------
--------------------------SQG---AGKLDFS---------------------
------------------------------------------------------------
-------------------AVIRLYRPAGAAR---------------------------
>NC_008358.1|c3|1884138-1885028|-|YP_760528.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MTKIAFIGLGNMGGGMCANLV-KAGHAVA
AFDLNGEAVAAAAA---K-G--AR--AAASVADAVKDADV---IVSMLPAGKHVLGVYFG
-PDGVGAH-AAKGTLLIDCSTIAVTDAREAHS-QAE-QAG-FLMVDAPVSG--GVAAAEA
G---TLTFMAGGTAAAYE-RAAPILKAMG----KN--------------------IFHA-
--GG-AGNGQAAKIANNMLLGISMIGTCEAFNLAEKL-----------------------
--GL--DA---ETFFRISS----V-SSGQCWSMT-SYCPAPGPVPTSPANRDYK-PG-FA
VAMMLKDLHLA--ADAAKAAGADIRLGEMAEGIYQNLS----------------------
--------------------------ERG---FDGLDFS---------------------
------------------------------------------------------------
-------------------GVMKDLKGEL------------------------------
>NC_008146.1|c2|1157822-1158694|-|YP_638232.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MTTIAFFGLGHMGGPMAANLA-KAGHTVR
GFDPVPALRTAAED---N-G--IS--TFESGTEAVAGAEV---VITSLPNGAIVKSVY--
--DEVLPA-AADGTLFIDTSTISVDDAREVNA-AAA-AKG-FAQLDAPVSG--GVKGATA
G---TLAFMVGGDDAAVE-RARPVLEPMA----GK--------------------VVHC-
--GA-SGTGQAAKLCNNMVLAVQQIAIGEAFVLAEKL-----------------------
--GL--SA---QSLFDVIT----G-ATGNCWAVH-TNCPVPGPVPTSPANNDFK-PG-FA
TALMNKDLGLA--MAAVSSTGASAPLGSHAAELYQTFA----------------------
---------------------------ED---HADKDFS---------------------
------------------------------------------------------------
-------------------AIIETLRG--------------------------------
>NC_009077.1|c2|1165650-1166522|-|YP_001069387.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MTTIAFFGLGHMGGPMAANLA-KAGHTVR
GFDPVPALRTAAED---N-G--IA--TFESGTEAVAGAEV---VITSLPNGAIVKSVY--
--DEVLPA-AADGTLFIDTSTISVDDAREVNA-AAA-AKG-FAQLDAPVSG--GVKGATA
G---TLAFMVGGDDAAVE-RARPVLEPMA----GK--------------------VVHC-
--GA-SGTGQAAKLCNNMVLAVQQIAIGEAFVLAEKL-----------------------
--GL--PA---QSLFDVIT----G-ATGNCWAVH-TNCPVPGPVPTSPANNDFK-PG-FA
TALMNKDLGLA--MAAVSSTGASAPLGSHAAELYQKFA----------------------
---------------------------ED---HADKDFS---------------------
------------------------------------------------------------
-------------------AIIETLRG--------------------------------
>NZ_CH482384.1|c5|3049320-3050210|-|ZP_04935323.1|hypothetical_protein
---------------------------MSASLPSLAFAGLGLMGVPMCRRLL-AAGYPLA
VWNRSPGKREVLAA---E-G--AK--AVEVPAELAADAEI---LMLCLADTAAVREVVFG
-AGGIVEN-ARPGQLLVDFSSAEPAATREMAA-ELEARCG-VRWVDAPVSG--GTPGAES
G---SLAIMAGGRAADIE-RLRPVLSQLG----QR--------------------LTRM-
--GE-VGAGQVTKVCNQMIVACNALVIAEVVALAERA-----------------------
--GV--DA---SLVAPALA----G-GFADSKPLQ-ILAPQ-------MAESRYE-PVKWH
VRTLLKDLDTA--VKLSREQGAATPMSGLAAQLMRLHG----------------------
--------------------------SQG---YLERDPA---------------------
------------------------------------------------------------
-------------------TLVEQYRTAVE-----------------------------
>NZ_AAQW01000001.1|c4|4413256-4414188|-|ZP_01366762.1|hypothetical_protein
-------------MALPVPIRCVLEFAMSASLPSLAFAGLGLMGVPMCRRLL-AAGYPLA
VWNRSPGKRELLAA---E-G--AK--AVEVPAELAADAEI---LMLCLADTAAVREVVFG
-AGGIVEN-ARPGQLLVDFSSAEPAATREMAA-ELEARCG-VRWVDAPVSG--GTPGAES
G---SLAIMAGGRAADIE-RLRPVLSRLG----QR--------------------LTRM-
--GE-VGAGQVTKVCNQMIVACNALVIAEVVALAERA-----------------------
--GV--DA---SLVAPALA----G-GFADSKPLQ-ILAPQ-------MAESRYE-PVKWH
VRTLLKDLDTA--VKLSREQGAATPMSGLAAQLMRLHG----------------------
--------------------------SQG---YLERDPA---------------------
------------------------------------------------------------
-------------------TLVEQYRTAVE-----------------------------
>NC_011770.1|c3|1887021-1887911|+|YP_002439357.1|putative_3-hydroxyisobutyrate_dehydrogenase
---------------------------MSASLPSLAFAGLGLMGVPMCRRLL-AAGYPLA
VWNRSPGKRELLAA---E-G--AK--AVEVPAELAADAEI---LMLCLADTAAVREVVFG
-AGGIVEN-ARPGQLLVDFSSAEPAATREMAA-ELEARCG-VRWVDAPVSG--GTPGAES
G---SLAIMAGGRAADIE-RLRPVLSRLG----QR--------------------LTRM-
--GE-VGAGQVTKVCNQMIVACNALVIAEVVALAERA-----------------------
--GV--DA---SLVAPALA----G-GFADSKPLQ-ILAPQ-------MAESRYE-PVKWH
IRTLLKDLDTA--VKLSREQGAATPMSGLAAQLMRLHG----------------------
--------------------------SQG---YLERDPA---------------------
------------------------------------------------------------
-------------------TLVEQYRTAVE-----------------------------
>NC_002516.2|c4|3714915-3715805|-|NP_252002.1|putative_3-hydroxyisobutyrate_dehydrogenase
---------------------------MSASLPSLAFAGLGLMGVPMCRRLL-AAGYPLA
VWNRSPGKRELLAA---E-G--AK--AVEVPAELAADAEI---LMLCLADTAAVREVVFG
-AGGIVEN-ARPGQLLVDFSSAEPAATREMAA-ELEARCG-VRWVDAPVSG--GTPGAES
G---SLAIMAGGRAADIE-RLRPVLSRLG----QR--------------------LTRM-
--GE-VGAGQVTKVCNQMIVACNALVIAEVVALAERA-----------------------
--GV--DA---SLVAPALA----G-GFADSKPLQ-ILAPQ-------MAESRYE-PVKWH
VRTLLKDLDTA--VKLSREQGAATPMSGLAAQLMRLHG----------------------
--------------------------SQG---YLERDPA---------------------
------------------------------------------------------------
-------------------TLVEQYRTAVE-----------------------------
>NC_011988.1|c2|742158-743030|-|YP_002547512.1|oxidoredutase
-------------------------------MTRIAFLGTGLMGEPMARHLA--ADFEVV
VWNRSPQKAQALSD---V----AR--VAASPADAARGADV---VISMLLDGPATRATLED
--SGAMAA-AGEGALIIDMGSVEPACDRDLAS-LAR-QMG-KRFLDAPVSG--GVAGAKA
K---SLSIFVGGAPEDFA-AAVPILEKLG----RP---------------------TLM-
--GP-VGTGQTAKLANQLIVAVTIGAVAEAFRLAQSA-----------------------
--GC--DP---ATLRDALR----G-GFADSRILD-LHGER-------MVTGNFT-PG-GR
SAAQLKDLNNA--LSVAAEHDLTLPLSETVRAGFTDLV----------------------
-------------------------QNKG---GADLDHS---------------------
------------------------------------------------------------
-------------------A-YYLWLQQIQPVKD-------------------------
>FJ915123.1|c1|16772-17647|+|ADB23388.1|3-hydroxyisobutyrate_dehydrogenase
-----------------------------MAARKVAVLGLGGMGGGMAHRLL-DSGVELT
VWNRTAAKAAGLVA---A-G--AR--QADSPAEAVADADV---VLVSLADEEAVEQVLFG
---AVCPA-ARPGTPIIDTSTVSPTYAREAGE-RAA-KAG-VKRIEACVVG--NPHQARN
G---ELRVLTAGTQADLA-EVSDVLALLG----PQ--------------------VVYL-
--GP-PGMAATMKLVFNAMLGAQVASMAEAVAYGERS-----------------------
--GL--DR---DMLLMAVE----R-SGFSSKVMS-FRAAL-------MRERKYE-PAAFR
TRLMNKDLRLA--LAEAAKVGVDMPVIERSAVTFTEAI----------------------
--------------------------DAG---YGDQDAA---------------------
------------------------------------------------------------
-------------------AVHEMLSRNDA-----------------------------
>NC_013595.1|c14|4617104-4617988|-|YP_003339794.1|3-hydroxyisobutyrate_dehydrogenase_family
-------------------------MTVVSSDNELAFVGLGGMGAGMALCLR-GAGFPLV
VHNRTAAKAAPLAE---A-G--AR--VAASGAEAAHGARI---VILSLSDQAAVEEVLFG
---ELAGR-LRPGALVVDTSTVSPAYSADATE-RLA-RTG-ARRVEACVLG--NPAMARA
G---KLRIFTAGRREDAA-GAHDVLEALG----QD--------------------VLHV-
--GP-AGSACVLKLSFNLILGNQIAALAEAVLLADSA-----------------------
--GL--DR---DLLLTAVT----KSGFSSPTLA--FRAEL-------MRTRHYEPPA-FR
SALMEKDLRLA--VGEAALHGLELPVTAGAADRFTEAV----------------------
--------------------------LAG---DGDKDAA---------------------
------------------------------------------------------------
--------------------VVAELRSTVR-----------------------------
>NZ_CM000914.1|c4|1059102-1059989|-|ZP_06776173.1|3-hydroxyisobutyrate_dehydrogenase
------------------------------------------MGGAMARNLL-TAGFPVT
VHDIRREAAAAHLA---A-G--AD--WADSAADCAAAVDV---LITMLPGPRQVEAVLLH
--AGAAAA-LRPGSTWIDMSTSAPATARRIAEQQLD-GRG-VRHLDAPVSG--MAKGAEA
G---TLQIFAGGDAAVYT-ELRPVLTAMG--DPER--------------------IFHV-
--GP-RGTGYTVKLMINLLWFSHLVATSEVLTLGVKA-----------------------
--GV--DL---AVLRDSLI----A-SPANSNFLEHDIQDL-------LTAGDYD-ES-FA
MALACKDLGLA--VDLGRDVGVPVELSALVEQIYRRGL----------------------
--------------------------AQYGGPAGEMIPV---------------------
------------------------------------------------------------
-------------------RLYEELAGIELRIPAGPGDAR-------------------
>NC_009767.1|c3|3486120-3487028|+|YP_001432789.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MERLGFIGLGRMGQAMARRLL-TAGFPLT
VHNRTRSRANALIA---A-G--AV--WADTPSEVAARSDM---VFTILTDEQAVEAVYRG
-QGGLLST-DAPGRLFIEMSTIRTATILALAE-AVE-QRG-AHLLDAPVSG--TVAPARD
G---QLLILVGGRASDVE-RARPALQVLG----RR--------------------IIHL-
--GG-QGAGTTMKLALNMTMACFWGALAESLAIGRQF-----------------------
--GL--SL---DAMLDVYL----D-SPVAPPALRSKTPTLL------GETSEVA----FD
VAGVRKDLRSM--VATAQDAGVPAAVAAAALAHFAAAT----------------------
--------------------------AAG---YGERDLA---------------------
------------------------------------------------------------
-------------------AIVEYLADVARRTARPVFTLGEP-----------------
>NC_009445.1|c5|6419658-6420554|+|YP_001208054.1|putative_3-hydroxyisobutyrate_dehydrogenase
-------------------------------MSNITCLGLGAMGSRMAASLL-KTGHRVT
VWNRSAERAAALVA---A-G--AV--VADTPRAAVRQADV---VMAMTRDDNTSREIWLD
PATGALDG-MREGAIAVESSTLSPAWVQDLAR-HAA-ARA-IRFVDAPVVG--SRPQADA
G---QLIFLAGGDAADVA-LAAPVLECMG----SA--------------------VHRT-
--GP-VGSGALLKLAINALFAVQVTAMAELIGALDAA-----------------------
--GA--DI---AGAIEIIG----A-TPVASAAAKGAASA--------MLSGRFA-PL-FP
VELVAKDLAYV--RQLGTPVAAGMPMTTAAAGVMQSAL----------------------
--------------------------AHG---FGGDNLT---------------------
------------------------------------------------------------
-------------------GIVRLFRPGTAQPSDTRA----------------------
>NC_013440.1|c9|2034055-2034909|-|YP_003265943.1|3-hydroxyisobutyrate_dehydrogenase
-------------------------------MDTIAFLGMGAMGERMARRLL-DAGHALR
IYNRSAARTAPLVA---A-G--AS--AFATPREAASGADV---VIAMVTDDQASRTVWLA
PESGAASG-LAPEAIAIECSTLTPGWIHELGA-AVP------RLLDAPLLG--SRPQAEA
G---ALAFLVGGEGELLE-RARPLLSLMG----GA--------------------IHHV-
--GA-RGTGAMLKLAVNALFGVQVAALGELLGALARA-----------------------
--GL--DP---AHTVEILG----T-LPVTSPAVRAAAGLV-------IAGRDAP---LFP
IDLVAKDFRYA--VAMAAGRGAELPVSAAAGEQYERAR----------------------
--------------------------AAG---LGDRNIH---------------------
------------------------------------------------------------
-------------------AVARLFNG--------------------------------
