>NC_007777.1|c4|1181033-1183123|+|YP_480105.1|FAD_dependent_oxidoreductase
----MAAGSGCGASQQSPLVSSTPVLCAYDEVNLCETKHARPDAKIQPVGEADRVSRKLR
QRSDLMTNEKAHSPKGLPVIRQTTSE---TDVVVVGAGIIGLANALQLAKR--GLRVTLI
DNLRDK----KHSYKVGESFLVF----------------TSAFLRTVGELDEFITE--ES
FAKLGVWF--SHGTENRSDFH------------DATEWAINADPHPPHYLYDLAPDKKWF
RCMFLDMQIVRPEAEDSMCAAVRRRAGITFVDTARVSDIQIS--------------PGA-
-DWHQVEWLDGT--TGHSNII----RTRWVVDCSGRNRLLARGRGHAAERRELTDGFQ--
T-TAVWGQFEG--VTDGLFGDEWTHTFPNGRDTQRDLY--TVHLWG-----A-GY---WI
WVIRL-------SKE-RISVGATFDQRSA-PPG----RTPQEQ--FWNLIRRH-PV----
----LDK--VIAPESLLE-----FRTYRNV-QHWTDTFVSP-QRYAMVGDAGSIIDAYYS
QGIALALVTSWHLANIVQDDV--RSGNLDRAY---IERVNRAT--RQDWHM-LRAMVRE-
-KYTAAIADPRFFVLSHVLDMMVFWSVGST-------------------RSALT-----R
WLVDTEGD-------TTRETPKNRRVRR-----------------------RLQSTLFYS
RAPLWRWLPPETVHWIQSRLQANL-AARARWR-------LDHGVKLPTVRSVQNVTAPLP
KLWWLAI-------------------GGDRGRDISAHDLVEPAELRPEGTATWLDRLPVP
A-------------NTRLRWVIRLRPYALLAGFSAAYLWDGADTAIRRLRLLVRRPSDSA
TASELANHEALLRKNE
>FJ483966.1|c1|37950-39179|+|ACN64845.1|PokO1
------------------------------------------------------------
--------------------MEEHTR---TDVCVVGGGPAGMTLALLLLRS--GARVTVV
ERSSSL---SR--EYRGEILQPG----------------GLAVLDEIGVLKGATDR--GA
HVLERFRL--VEHGR------------------VLMSFDYRRLQSPYNYLL---------
-------SLPQAHLLAELLDR-CQEFPEFRYVVARVNGLIRE--------------GD--
-AVRGVYAKAQD----VTHTV----RAACVVAADGRHSQVRRLAG---IDHVRQDVFD--
Q-DVVWFRLPATERLGEVM-------------VNRAGGNPVLAYDS-----H-PG-----
----------------AVQMGWTLPKGEW-KRLAP--LGIGEV--RRRITAAT-PQ----
----FAD-RVEGALRSFA-----DVSLLDVFGAAAERWTG--DGLVLIGDAAHTHGPLGA
QGINLAVQDAALLHPILLAAV--TDGDVSAAR---LGEFERIR--RPHIKA-VMKFQAV-
-QSRMMLSADSLA-----TFLRPKLARVVM-------------------RTPIG-----A
KFTQR----------IAFGAPGIRVADN--------------------------------
-------------------------LFTVNEK-------E--------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_011884.1|c2|3019980-3021110|-|YP_002483738.1|geranylgeranyl_reductase
------------------------------------------------------------
----------------------MFLE---YDLIIVGGGPAGTTLALFAHRA--GLKTLLL
DKARFP----R--DKICGDAIILP---------------GIKILEELELTAALHQG----
PHSYSVNF--------------------------HCFTESEHLQAPGSHCL---------
-------MVKRLYFDHVLFT--AAKAVVDTCEGAEVEQLLQQ--------------EG--
-QVYGVRGRLQN---QEEFEF----TAKVVVGADGCGSVVAKKAG---VFKFEPQHYG--
--VATRAYYRH---------------------LPLPYGKAIEFYYF-----Q-ECLPGYL
WIFPV-------DQE-TVNVGVGVEPSPN--------QALPKL--HQQLLES--PL----
----LKS-RFAEAELIGQ-----IQAWSLPLASKQRKIHG--NGFILIGDAAGLIDPFWG
DGIDKAMLSAKVAAQVLAEVC--RGQDYSAAA---LQDYPDSL--WSQLGA-KFQYSCR-
-LRQR-FHKPPFF-----PLMTRM-----------------------------------E
ILNQF-------------------------------------------------------
-------------------------YFRNQGK-------IIKPD----------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_003296.1|c3|1793199-1794506|-|NP_522982.1|putative_transmembrane_protein
------------------------------------------------------------
----------------MSATMQSETV---YDAVIVGGGVAGGTAALLLRQR--GCSVALL
EKRPL-----DYYKALCTHFIQPS---------------AVPILRRVGLDHVLEPE-AST
RTKASFVT--SEG--------------------VIDTPGGYTDDAATAYAY---------
-------NLERRVLDPALRAR-ARSEGVDLLDEATVTACRLQ--------------ADGL
WRVEADADTDTD-----GARHPRVLRARVVIAADGRRSQMAQWLN---NAAVQHDNQR--
--AAVFAQFEG---------------------IAVPGGNRSLFILA-----E-RE---MG
FVYPL-------TGG-RTLLSAYVEKDRA-AQWRHSADAGAPL--LDFFARLA-PG----
----L---DLAGARLLTP-----VLGYADYPSQFRQPVCG---AVPFIGDAALSLDPMSG
VGCGFAMEAAALLDEHLGPALQAQGNSAIGPA---LDAYASRF--DTHFAAHARGIVAD-
-SLIA-----KQP-----AAQAALYRAVIA-------------------DPALQ-----R
DYLAL----------TGRLITPQAFQR---------------------------------
-------------------------AYFSAHV-------RSQRAATTHAHPPERASELS-
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ACEZ01000180.1|c2|116456-117700|-|ZP_05534728.1|monooxygenase,_FAD-binding_protein
------------------------------------------------------------
--------------------------------------------------------MALL
ERRSSM----DAHKVLCTHYIQAA---------------AYPVISELGLTDALDGI--GA
IRNSADYW-TKW---------------------GWIRPEAETGPGVLPHGY---------
-------SVRRQSLDPLLRRTAAGTDGVDLRLGHTVNELLVE--------------DG--
-RTTGVAGTSAD----GSFDL----RAPLVVGADGKDSTVARLAG---APSETAENHR--
--FSYFAYFRG---------------------LRHPEGRTSARVYY-----LDPD---NA
YVMPN-------EDG-VTVVAAVVSKARL-DDFR---EDIEGA--YLDFVRSL-PE----
-----GP-DIDKAERISK-----VIGTVNY-PLIARQPSG--PGFALIGDAALTSDPLSA
VGCAWAMQSASWLVEATAPAL--TGDDPLDGA---LADYAKRH--ATETGA-HQHLIAD-
--YALA---RPFN-----EIEAFMFEGAAR-------------------DARLA-----E
HFHIF----------GSRLITVE-------------------------------------
-------------------------DYMAPEI-------VARTEKVTGWSLSEES-----
--------------------------LRILSGGAPGAGTHTTGPDGTRQESTEAAR----
------------------------------------------------------------
----------------
>NC_013235.1|c4|5715060-5716295|+|YP_003204388.1|monooxygenase_FAD-binding
------------------------------------------------------------
---------------------MRRAH---FDVVIAGASLAGCTAATLFARQ--GLSVVLL
EAHRDP----NHYKRACTHFIQPT---------------AWPTISRLGLGAAIRQA--GG
QPNRLSIW-TRWG--------------------WLDFPGPAGHTGHGEIGV---------
-------NIRRAQLDPLVRAQAAREPRVTVLMGQRVSQVVVR--------------AG--
-RAVGVRAGDPG----RETEY----FGRLIVGADGHRSRVADAVG----PAVTSPHGR--
--FVYFAPFTGVG-------------------LPDDAS--------------------RM
WMLEPDIAYAFPNGE-VTILSVMPTLDQL-PDFR---KDLRGN--YFARLGRL-PD----
-----GP-DLSRAEQVGE-----LSGVLNY-ACAARPPAA--PGLALVGDAAMTSDYLWG
TGCSFAFRSAAWLVDATAPEL--IRGADPQVG---LRRYATQH--RRALAG-HHRLMSD-
------YATGRAF-----NPVERALYAGAV-------------------RDPLL-----A
RHVAA----------FGERRIGVRQFLA--------------------------------
-------------------------PGMLARS-------VLANRPRPTAAA---------
------------------------------------------------------------
------------------------------------------------------------
----------------
>FP565575.1|c1|594157-595380|-|CBE67770.1|putative_Electron_transfer_oxidoreductase
------------------------------------------------------------
-----------------------MPQ---TTVIIVGAGPAGSVLAGLLARR--GIDALLL
DKATFP----R--EKICGDYLSPG---------------TVGLLDQLNLLDLVRSA--GA
RRLLGMTI--ISPDGTTF---------------TAEFPAISRINAGPPFAL---------
-------SIPRAILDSLLLKW-ARGFGARCVEGLRVTDLILE--------------NG--
-QVCGVTGIGPT----GPETY----RGRIVVGADGRDSVVARRLG---LYQPHPTLHR--
--MALVAYYEGVSTLQDHGLISI---------GDRSYC--ILNSIG-----E------W-
----------------LTNAAIVVDQGIV-QGWK---GQLDEL--FDGTLQAF-PL----
----ALS-ALRDTVRRGS-----VRCLGPL-AFRASRSAM--AGALLIGDAAGFYDPFTG
EGVGHALCGAQLAASEIVSACAEGDGGLTEAH---LARFDHHQ--RNAVRG-RRRLGIA-
-LQAI-IRRPRVA-----NAVARLLCR----------------------RQSLA-----N
LLLGI----------IGDLLPPHA------------------------------------
-------------------------LLSPPAL-------FNVLHRT--------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ACEB01000009.1|c1|1715-2929|-|ZP_03709979.1|hypothetical_protein
------------------------------------------------------------
-----------------MSTKKERRI---ADVVIVGGRVAGASLAVRLASL--GLEVLVL
ERGKIG----S--DTLSTLYIHQP-----------------GVEELRGLGIEMGDTLEGA
PAISKMVY--EVN--------------------DIRIVGKGPWYGKGNVSY---------
-------APRRSRLDRALCIK-AERAGAIILHEAKVTSVNFH--------------GG--
-RACGVTFRRAG----NEYSV----RAHLIVGADGMRSLVAEEVG---AVSYLERPKL--
T-CCYYGFFRGLE-------------------RPFSQY---------------QGHRRWI
GVIPT-------SD--SHLVACYVPQDEF-TKAKS--DPKGTF--FSSLQQVS-SS----
----LSQ-EVAQAQQIGR-----LIGMGDQ-QNFFREASG--PGWVLVGDAGHHKDSLTA
YGITEALQQSSFLAEELA-----KVPIDVPEA---VDSATKMFGTRRDDES-LPRYIPT-
-LSVA---RLEVS-----DARMTMLRRIQD-------------------DPEMC-----D
LYFSA----------MAGVIPTDD------------------------------------
-------------------------FYKKLSD-------QGILIKK--------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_008278.1|c9|2763770-2764906|+|YP_712763.1|putative_hydroxylase
------------------------------------------------------------
---------------------------------------------MLFARQ--GYRVLLL
EKAQFP----R--DTLSSHYIHQP---------------GVALLDRWGLLGDLRDA--GC
QPIDQQSY--TAP--------------------GVRLAGFSLPVDGNRTTY---------
-------APRRFVLDPILAAG-AVAAGVEFRESCEVTDLLFD--------------GD--
-RVVGVQYTTPG---GAVATD----RAWLVVGADGMRSVVARRAG----AGNVIEHPR--
MTCTYYSYWAG---------------------VPAHFE--LYERPG-----R------WI
GVIPT-------NDD-LTLVMTYFPQAEF-TRVR---TRVEAA--YLEAVRATAPA----
----LYE-RMAAGRRVER-----LYGTGQQ-ENYFRKAFG--PGWVLLGDAVHHKDSITA
RGITDAFIQARLLTERIGQGL--HDEAALEVA---LKAYEEDL--RDEFLNLYQGVLNV-
------------------AEL----------------------------RPEGR-----T
ELLGK----------LVGHQELIDRYFS--------------------------------
-------------------------TVSGACS-------LDDFYNDELLAVLDQS-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_013093.1|c14|5316799-5317956|+|YP_003102177.1|monooxygenase_FAD-binding
------------------------------------------------------------
-------------------------M---YDTVVVGARCAGASTALLLARR--GWRVLLL
DRAEFP----S--DTMSTLYVHQP---------------GVALLRRWGLLDAVIAS--GA
PALDSVRY-------------------------RVEDVDLAAP-APEQPGY---------
-------GPRRRVLDSILVEA-AVAAGAEFADRSTVVDLLRE--------------GD--
-RVAGVRFRGPD---GRERRA----HARLVVGADGMRSRVAELAG---AATTAEDPRL--
S-CVYYSRWAG---------------------LDTGFG----FHER-----T-GR---WI
ATIPT-------HDG-ETMVATYFPQSRF-DEVRA--DARAAH--LDALATTA-PS----
----VAA-QLEGGEQVDR-----LLGTGDQ-RNFFRRATG--PGWALVGDAGHHLDTITA
RGITNAFTQADLLAGSVGDA---PGDQAA------LDGFAARR--DEAMVDGYAATLALA
RLEVT-------------PARLALLRAVAR-------------------RPEWT-----R
DYFAV----------VAGLMPME-------------------------------------
-------------------------DLLDGEL-------LDLI-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ADBZ01000015.1|c1|66432-67616|-|ZP_06217414.1|monooxygenase_FAD-binding
------------------------------------------------------------
-------------------------M---YDVVVVGARCAGAPTAMLLARQ--GHRVLLL
DRSAFP----A--DKLSTLYIQQP---------------GVARLARWGLLDALRAT--GC
PPLDHVVY--ELG--------------------DVRVEGCCSGIDGIRAAY---------
-------APRRSILDPLLAGA-AVDAGAEFRDDCRVTGLLWE--------------DD--
-RVVGVRTDRGDE------------RAALVVGADGMRSTVAGLTG---APTTTSHPPL--
T-CAYYAFWDG---------------------PKTHFE----MYEG-----D-TG---WV
SAVPT-------NDG-AVLIAAYYPQQRF-DEVRH--DARAAY--LDNVRTNA-PR----
----LYE-QMERGRQIGG-----VHGTGDQ-QNFFRRAHG--PGWALVGDAGHHKDSLTA
RGISDAFMQADLLAESVGEHL--ADRTRLDAA---LADYDREREQRLMENYQATLLVAQ-
-AEAR-------------DKRRALLRAVGS-------------------SPELT-----T
RYFDA----------VAGIVPLRE------------------------------------
-------------------------LYTPELM-------ALMSAPTAP------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_003155.4|c7|1553040-1554224|+|NP_822426.1|hydroxylase
------------------------------------------------------------
-------------------------M---FDAIVVGARCAGASTAMLLARS--GYRVLLL
DRSAAG----S--DTLSTHLVHQP---------------GVAALARWGLLENVRAS--GC
PPLDRAVY--EVA--------------------DIHLEGCARGVEGQRASY---------
-------APRRHVLDAILVDA-AVAAGVEFRDRCQVTGLLRD----------------GT
GRVVGVEGRHGG----RSFTE----RARLVIGADGMRSTVARLVE----APYTVTDPR--
LTCAYYTYWPD---------------------VPA-----TLELYE-----RTGS---WV
AAVAT-------NDA-ATLVLAYFPQVRF-EEVR---TDARGA--YLEQIRTTAPA----
----LHE-RLRGKEPAER-----LRGTGDQ-QNFFRQATG--PGWVLVGDSGHHKDSITA
RGISDAFLQVDTLVRHVDGPL--GGDPVRLDA--ALEKFAEER--DSALTP---------
-GYESTLAVARLA-----PHEQRLSLLRAVQT-----------------DPELT-----A
IYFDM----------VAGIGS---------------------------------------
---------------------------------------AGALYTPKLLALL--------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_013947.1|c2|1229517-1230710|-|YP_003509953.1|monooxygenase_FAD-binding_protein
------------------------------------------------------------
-------------------------M---FDAIVVGARCAGSPTAMLLARA--GHRVLLL
DRAAFP----S--DTLSTHLIHQP---------------GVAALDRWGLLDKLRDT--GC
PPLEKAVY--EVA--------------------DVRLEGCSRGVDGHRAAY---------
-------SPRRHILDAILVDA-AVAAGAELRQNCRITGLLRD----------------ED
GRVTGVSGVHQG----RRFTE----RARLVIGADGMRSSVARLIK----APYTATDPK--
LTCAYYSYWADVPAD-----------------LELYEQ-------------P-GS---WV
AAVPT-------HD--ATLVLTYFPQQCF-RQVR---ADASRA--HLDRVKDTAPQ----
----LFE-RLRGKKRLER-----LRGTGDQ-RNFIRQATG--PGWALVGDAGHHKDSITA
RGISDAFFQAEALVRNIAEPLT-EDPDLLDKA---LRRYARER--DGALTP---------
-GYESTLTVARLE-----PPHAERLAVLRAVQS----------------DPELT-----S
IYFDM----------VAGIAG---------------------------------------
---------------------------------------PSALLTPRLYELLTVQ-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_013131.1|c4|2921921-2923114|-|YP_003113336.1|monooxygenase_FAD-binding
------------------------------------------------------------
-------------------------M---YDVIIVGARCAGAATALLLARQ--GVRVLLA
DRTTFP----S--DTVSTHLLHPA---------------GVARLREWNLLEPLLAT--GC
PPLDAISY--HAAE-------------------DLVLRGAPYAYEDVTISV---------
-------APRRTVLDALLVEA-AVAAGAELREGASLRNVLWE--------------DG--
-RVVGAEFGSGADSSGGSGVFTE--RASLVIGADGRHSTVAREVG--AKLVRDAGTFG--
--CQFYGYWSG---------------------LPDEG---TQIFIG-----G-GQ---AV
LAYPT-------HDR-HHLVLVGWPHARF-AEVK---QDIDRH--FLAAVATSAPA----
----VRE-HLTDDARSER-----ITGSGDL-ANYVRESSG--PGWVLVGDAAMAKDAVTA
QGIGDAFSQAQSLAERLPAALAAGPRAVDAST---AAHVADRD--RDGATA-FETTVAFA
MGGNS-------------SELLPVLRAIAD-------------------RPDLV-----S
MFYGI----------YAGRVTMDEFAA---------------------------------
-------------------------AVG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ABYB01000313.1|c1|19120-20313|+|ZP_04696966.1|putative_oxidoreductase
------------------------------------------------------------
---------------------MSESR---YDVIVVGARCAGSPTAMLLARK--GYRVLVV
DRAVFP----S--DTLSTHLVHPP---------------GVAALRGWGLLDRLVAT--GC
PPIHTYEF--DF---------------------GSLVLPGAPGTEAEPYAY---------
-------APRRTVLDKLLVDA-AREAGAEVREGFTVTGLVLG--------------DAG-
-DVVGVRGRGPH---GPEVTE----RARVVLGADGLHSLVARAVD---APRYNENPKL--
M-VGYYSYFSG---------------------LDMDGVFKAHSRPY-----R------SF
GAWPT-------HDG-LTLVGGCWPFAEF-NDIRK--DIEGNY--FKNF-ALA-PA----
----WEE-RIRDARREDR------IVGAAL-PNFFRKPFG--PGWALVGDAGYCKDFFTA
QGISDAFLSAEMCAGSLDDAL--SGRAPFDTA---MAAYQAAR--DRHARP-VYDFTLQ-
-VSTL----EPLS-----PEFEKVLEGIDG-------------------NQQGM-----D
AFARV----------NAGVTSME-------------------------------------
-------------------------RFSADWG-------GAV------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_007777.1|c16|3463795-3465003|-|YP_482021.1|monooxygenase,_FAD-binding
------------------------------------------------------------
-------------------------M---YDVIVVGARCAGSPVAMLLARR--GHRVLLV
DRVSFP----S--DTISTHYLQQA---------------ALLRLREWGLLDALTAT--NC
RPITDMTV--SHL--------------------GVVIRGFADPVDGLAFSM---------
-------APRRIVLDKLLLDG-AVAAGVEVREGFSVRDLIRH----------------DD
GTVAGIVGRDAT---GAVVEE----RATLVVGADGRNSVVADLVG----ADFYKVVPA--
ASFIYYSYFSG---------------------LDWQFHSRFGDHEQ-----C-AG---WP
T-----------HDG-LTLVTAMRNLEDF-EEFR---ADIDGS--LRRTFRSVAPE----
----LAEDLDSHGVQEDR-----YYGIRYP-DNYYRTSYG--PGWALTGDAGYHKDPVTG
LGITDAFRCADLLTEHVDQAL--RGDRPMDEA---LAEYQRLR--DEESAG-AFNFTTT-
------LGELNFP-----PHLVALWRALPN-------------------NETAR-----A
QFFGM----------IAGVVPSSVFLA---------------------------------
-------------------------PENVESI-------MLAAAAV--------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ABYC01000006.1|c1|6511-7701|-|ZP_04700335.1|monooxygenase_FAD-binding_protein
------------------------------------------------------------
---------------------------------------------MLLARQ--GHRVLVV
DRSSFP----S--DAVSTHYIHQA---------------GLLKLREWGLLDEIVAA--KT
PELKKMHY--SYR--------------------GIHLNGFAAPVDGLDAVY---------
-------APRRRVLDEILVNA-ARRAGAEVLESFTVTDVVAV--------------EG--
-QVVGIRGREGD---GPEREF----RATVVVGADGFHSTVAKKVG----AELYNVRPA--
AGFIYYSYYSG---------------------LDWGLH---HKAGL-----N-EQ---WF
GTWPT-------NDD-LSMLAVICSRAQL-KEFR---QDVENR--FHAVFDDVDPD----
----MGAQLRDQGRREED-----FKPMRYP-DNYYRRPYG--PGWALVGDAGYHKDPYTG
WGMTDAFLHGELLADRLHQGL--AGERPMDEA---LAEYHKVR--DEESAG-VYDFTTT-
-LAPL----TELP-----PFFRVTMDAMSK-------------------SQEWT-----D
RMLGL----------IGGVVEDHEIYA---------------------------------
-------------------------PDALERL-------YDDAGVPQDQRIYDPAG----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_DS999645.1|c1|44999-46240|-|ZP_06589126.1|monooxygenase_FAD-binding
------------------------------------------------------------
-------------------------M---YDVIVVGARCAGSPVGMLLARQ--GHRVLVV
DRSSFP----S--DAVSTHYIHQA---------------GLLKLREWGLLDEIVAA--KT
PELKKMHY--SYR--------------------GIHLNGFAAPVDGLDAVY---------
-------APRRRVLDEILVNA-ARRAGAEVLESFTVTDVVAV--------------EG--
-QVVGIRGREGD---GPEREF----RATVVVGADGFHSTVAKKVG----AELYNVRPA--
AGFIYYSYYSG---------------------LDWG----LHHKAG-----LNEQ---WF
GTWPT-------NDD-LSMLAVICSRAQL-KEFR---QDVENR--FHAVFDDVDPD----
----MGAQLRDQGRREED-----FKPMRYP-DNYYRRPYG--PGWALVGDAGYHKDPYTG
WGMTDAFLHGELLADRLHQGL--AGERPMDEA---LAEYHKVR--DEESAG-VYDFTTT-
-LAPL-------------TELPPFFRVTMDAMSK---------------SQEWT-----D
RMLGL----------IGGVVEDHEIYA---------------------------------
-------------------------PDALERL-------YDDAGVPQDQRIYDPAG----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ADGX01000129.1|c1|9111-10346|-|ZP_06416263.1|monooxygenase_FAD-binding
------------------------------------------------------------
-------------------------M---YDVIVVGARCAGSPLAMLLARQ--GHRVLVV
DRSTFP----S--DTVSTHYMHQT---------------GLARLRDWGLLDRLIAT--GV
PPIRNLTF--YYT--------------------GMLVEGFADPIEGIDAVY---------
-------CPRRTVLDKLLVDA-AREAGAEVIEGFTVTDLLFD--------------AG--
-RVTGIRGQVGD---GPEQEF----RSAFVVGADGRTSTVADKVG----ADFYKVVPA--
EGFIYYSYFEG---------------------LDWAMQHRTGLGEQ-----QFGT---W-
---PT-------NDG-QHLLSIIRPRAAF-SEFR---ADVEGS--FQAIFDNVLPE----
----LGEDLRARGRRVEE-----FRPMRYP-DNYYRRSNG--PGWALVGDAGYHKDPFTG
WGITDAFLQAQLLADRLHAGL--AGERTLDDA---AAEYVKIR--DEESHG-TFELTCT-
------LSKLVLP-----PFLDSVFNATAA-------------------SPRYI-----K
KFFAM----------IAGGADGHDFFE---------------------------------
-------------------------RESLAEL-------YEEVGTPADKRLLPAA-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_009921.1|c12|4739732-4740967|-|YP_001508255.1|monooxygenase_FAD-binding
------------------------------------------------------------
-------------------------M---YDVIVVGARCAGSPLAMLLARQ--GHRVLVV
DRSTFP----S--DTVSTHYMHQT---------------GLARLRDWGLLDRLVAT--GV
PPMRHLTF--SYT--------------------GLHLEGFADPIDGITEVY---------
-------SPRRIILDKLLVDA-AREAGAEVIEGFTVSDLLFD--------------DG--
-RVTGIRGRTGE---GPEQEF----RAAFVVGADGRTSTVADKVG----ADFYRVVPA--
AGFIYYSYFEG---------------------LDWTFQHRTGFGEQ-----QFGA---W-
---PT-------HDG-RHLVSIIRPRSAF-SEFR---ADVEGS--FQAIFDAVVPE----
----LGEDLRTRGRRVEE-----FRPMRYP-DNYYRRSHG--PGWALVGDAGYHKDPFTG
WGITDAFLQAQTLADRLHSGL--AGERTLDDA---AAEYVKIR--DEESHG-TFELTCT-
------LSHLVLP-----PFLHSAFAATAQ-------------------SPRYT-----K
KFFGL----------IAGGVPGHDFFH---------------------------------
-------------------------PDNLAEL-------YEEVGMPAEKRLLSAS-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_008278.1|c13|3462339-3463574|+|YP_713402.1|putative_hydroxylase
------------------------------------------------------------
-------------------------M---YDVIVVGARCAGSPLAMLLARR--GHKVLVV
DRATFP----S--DTVSTHYIHQA---------------GLSRLQDWGILDRLVAT--EP
PAMRHLTF--SYT--------------------DIFLEGFADPIDGITEVY---------
-------SPRRTILDEILVDE-ARKAGAEVVEGFTVTDVIFA--------------DG--
-RAAGVRGRIGD---GPEREF----TARFVVGADGRNSTVAGLVG----AEIYRSVPA--
ACFVYYSYYDG---------------------LDWTFQHRTGFGQQ-----QLGA---W-
---PT-------HHG-QHLVAVMRRKERM-REFR---ADVEGS--FHEIIDQVVPE----
----LGEDLRANGKRAEN-----FRAMAYP-DNFYRRSAG--PGWALVGDAGYHKDPFTG
WGITDALKYSEVLAEKLHEGL--SGSRPTDEA---VEEYTKIR--DAESNG-TFELTCS-
------LAELSLT-----PYYDSVFRATSM-------------------SPEYT-----T
KFFGL----------IAGGIPGEEFFA---------------------------------
-------------------------PANLERL-------YEDVNMPADRRIVTRS-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ACEX01000652.1|c1|3635-4852|-|ZP_05519818.1|putative_hydroxylase
------------------------------------------------------------
----------------------------------MGARCAGSPLAMLLARQ--GHRVLVL
ERSTFP----S--DTVSTHYIHQA---------------GLSRLQAWGLLDRVIAS--GV
PPIRQLNF--EYT--------------------GIDIAGFADPIDGIDAVY---------
-------CPRRTVLDAILVDA-AREAGAEVIEGFTVTDVLFD--------------GD--
-RVTGVKGREGE---GPEREF----RATVTVGADGRNSVVADKVG----AEIYRRVPA--
ACFVYYSYYDG---------------------LDWGMHHRTAFGQQ-----QIGT---W-
---PT-------NDG-QNLLAVMRKNDRF-GAFR---RDVEGS--FQEVYDQVAPE----
----LGEELRDSGVRTEN-----FRPMRYP-DNYYRTSYG--PGWALVGDAGYHKDPFTG
WGITDAFKYGELLAEQLHLGL--SGQSPMDAA---LAEYVKLR--DEQSNG-TFELTCS-
------LAELSLT-----PYYDSVFRAASQ-------------------SPSYT-----A
KFFGL----------IAGGIHGDEFFA---------------------------------
-------------------------PQALEAL-------YEEVGFPQDKRLLTQA-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ABCS01000122.1|c1|16752-18476|+|ZP_01912459.1|halogenase
------------------------------------------------------------
-----------MKPPTETTAMTTSPTPMSSDVLVLGSSISALMSAAWLRRSDPSLSVTVL
GPPVGA----EKRPVVGESTVEP----------------AILFFRALGLGPYLDQR---H
ELKNGLTF--YHKLAPSQP--------------EDRRYTVHMPMAPLHHTAC--------
-------QLHRPAFDLELGRV-AAELGVRFVHG-RARDIALG-------QGQGQGQGNHK
DAEHRVEASLDG---GGEASL----RARFVIDATGRSRVLGRKVT----SYAKPSAQR--
--SAFWFRVRNFEALLPKLELSWRRP------AEYELWKSTHHFMG-----E-NN---WI
WAIPM----RDEQGEAVLSMGITWRPDLV-DHGI---RTLDDF--LAHVDDEH-PA----
----IAE-LVRSGEVLDT------NSYRNY-LYEAEQVYSD-EGWFLVGDAARSVDPLYS
TGLSMTVIQIEQIAEIIRRR---RGAGITAAQ---IAELEGLW--TAIAEVRQADIADQ-
-YETM---SDPFQ-----ACMRRYWNLSGWFNGVLPLWYAGYFN-----DPEAA-----T
ILRRM----------LGKGRPATHAAWR--------------------------------
-------------------------LFASTAR-------TLGEVEQADFDRTLDFDWMIN
RAFDRPVSEVGAQVGA----------MLQKRAHLRLNLIRLGGWRELPSQARYLARELAL
AKLVPLAFARNPALRRGEHEQEHEQAPATTWVGAWQPT----------------------
----------------
>NC_013131.1|c18|7306482-7308302|-|YP_003117048.1|FAD_dependent_oxidoreductase
------------------------------------------------------------
---------------------MSEDR---YDVAILGSGIGGSMLACILAKH--GVRTLLL
EGATHP----R--FTIGESLIPETGIRLRIIGEKYGVPEIGWIGAFHQLRDRVSSN-CGV
KRSFSFMY--HSEGEEHR---------------AGEVNQLPTLTPPIGPDS---------
-------HLFRQDVDAYLAAL-SIQYGAHFRQGTRIEDIKFG------------------
--EDEVELHAAG-----GVSF----KAKYLIDAAGMRSMVSDQLG----LRDETPRFKTD
T-RTLYTHMMNVPSADLLLPDPQRRG------VPSPLGQSTMHHIF-----D-GG---WI
WVIPFNNHRQATNP--LTSVGMMLDRRKH-PDAQ---GAPEEE--FRDIISRY-PT----
----IRR-HFDSAVAARP-----WIGSGRL-QYSSPHILG--PRVLQLPHAAAFVDPLFS
SGMSVLTVAVDLIAEQLLAAV--REDDFATER---FQFVEDVV--NTGFDH-YDMIVSG-
-AFDS-FASYDTW-----NAWNRNWALGNM-LG----------------AFGPL-----S
LLIRY----------LQSGDPSHLAKTT----------------------------EPGR
IGVLGSHLPNVVETMRGSQDEIE--AATRGEI-------THEEAGRRIFQRLGNLDFVPK
YMGFGDPAQGATATFTLLSGVRHVNWYRRHGSEAWKENCTFPLRTYAREALKWALESRRD
GLRRGRSGIRDILFADNQDWRYMPAAMSAHGTFWPPIPPAAEPESQAVQEITA-------
----------------
>NC_004129.6|c3|3089672-3091180|-|YP_259890.1|alkylhalidase_PltM
------------------------------------------------------------
-----------------------MNQ---YDVIIIGSGIAGALTGAVLAKS--GLNVLIL
DSAQHP----R--FSVGEAATPESGFLLRLLSKRFDIPEIAYLSHPDKIIQHVGSSACGI
KLGFSFAW--HQENA------------------PSSPDHLVAPPLKVPEA----------
-------HLFRQDIDYFALMI-ALKHGAESRQNIKIESISLN------------------
--DDGVEVALSN-----AAPV----KAAFIIDAAAQGSPLSRQLG----LRTTEGLAT--
DTCSFFTHMLNVKSYEDALAPLSRTRSP----IELFKS--TLHHIF-----E-EG---WL
WVIPFNNHPQGTNQ--LCSIGFQFNNAKY-RPT----EAPEIE--FRKLLKKY-PA----
----IGE-HFKDAVNARE-----WIYAPRI-NYRSVQNVG--DRFCLLPQATGFIDPLFS
RGLITTFESILRLAPKVLDAA--RSNRWQREQ---FIEVERHC--LNAVAT-NDQLVSC-
-SYEA-FSDFHLW-----NVWHRVWLSGSN-LG----------------SAFLQ-----K
LLHDL----------EHSGDARQF------------------------------------
-------------------------DAALEAV-------RFPGCLSLDSPAYESLFRQSC
QVMQQAR-------------------EQARPVAETANALHELIKEHEAELLPLG------
------------YSRISNRFILKV------------------------------------
----------------
>NC_011770.1|c4|2752984-2754498|-|YP_002440178.1|putative_alkylhalidase_pltM
------------------------------------------------------------
----------------------MSRT---YDIVIIGSGIAGSISAAILAKH--GLKTLIL
DAGQHP----R--FSIGEAMTPESGLLLRLLAQRFGIPELAFIASPEQIVRHIGSSACGI
KLAFSFAW--HAAG-------------------VDSAAEHVVAPPLDAPEA---------
-------HLYRQDIDFYALLL-ALQHGANARHHTRIEGFEFL------------------
--PEGVAIRLAD-----GESL----QARYVIDAAAQGSPLARQLG----VRTTDGLAT--
HTCSFFTHMLNVKAYEEVASNTDQSP------IPLFQS--TLHHIF-----E-EG---WL
WIIPFDNHSESTNR--LCSVGFQYNCLKY--QPS---GTPEQE--FSRLLDRY-PS----
----IAR-HFTEARVARD-----WVHAPRL-NYRSRTILG--ERFCLLAQAAGFIDPLFS
RGLITTFESILRLMPRLIDAV--RQDHWQLDR---FASVERHL--RNAVAV-NDRLVSC-
-SYEA-FRDFPLW-----NAWHRVWLSGSNL------------------GGAYL-----G
GLLQA----------LRDGQSGSAFDAHL-------------------------------
-------------------------ESARCPG-------HLSFDAPGYEDFFESACRVMD
GVR-----------------------QKRLSSADAISTLHRLLGQHAADLLPYD------
------------YANLDNRFLRKCRVQ---------------------------------
----------------
>AY394844.4|c1|1-844|-|AAQ90171.1|putative_halogenase
------------------------------------------------------------
----------------------MSRT---YDIVIIGSGIAGSISAAILAKH--GLKTLIL
DAGQHP----R--FSIGEAMTPESGLLLRLLAQRFGIPELAFIASPEQIVRHIGSSACGI
KLAFSFAW--HAAG-------------------VDSAAEHVVAPPLDAPEA---------
-------HLYRQDIDFYALLL-ALQHGANARHHTRIEGFEFL------------------
--PEGVAIRLAD-----GESL----QARYVIDAAAQGSPLARQLG----VRTTDGLAT--
HTCSFFTHMLNVKAYEEVASNTDQSP------IPLFQS--TLHHIF-----E-EG---WL
WIIPFDNHSESTNR--LCSVGFQYNCLKY-QPS----GTPEQE--FSRLLDRY-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_010995.1|c2|3521243-3523000|-|YP_001983453.1|halogenase_A
------------------------------------------------------------
----------------------MNKQ---HQVIILGSGIGGTVMAAILARH--GISVLIL
DKQAHP----K--FAIGESTVGHTSSMIQLIADRYDVPEIHNLVSFSRVRKHVCSS-SGV
KRGIGFVY--HRNDGTQR---------------EDEANQFIIPPHLHGLEN---------
-------HLFRQDIDAYIFQV-AVGYGADFKVDVNINDVDFT------------------
--EEGVTVHTNK------GNF----KADYVVDATGYRSVIADKLG----LRPKQNTMETN
T-RSAFTHMCHVAPYDDCIPANYHNMP-----IPWFQT--TVHHIF-----E-GG---WI
WVIPFNNTRTGTNP--LCSVGYTLDINKF-PDSG---QSAEDE--FLSIIQRF-PS----
----VKK-QFEFSKPARE-----WVKTGRL-QYNCENSVG--DRYVLLGHATGFVDPLFS
RGLAITMDCIFHLGNRLIQAV--RTQKFDARD---FAYVDQVT--RGGVSY-NDQLVSS-
-AYRS-WKDYRVW-----NAWQRVWAIGEAGLD----------------QLRLI-----K
QHELF----------LETGDENDLLKLE----------------------------CVTH
PGHLCPDSPEFATLFSEGKKLVD--AFDRNEI-------SAEEASSRIFQLIHDHELISP
KLRVFDPKV-----------------RNFGHKQIANLLSVLWGKTKSKQHIRRYYEIPVR
HMLKLFFKHGHEFFNPEFNIARRSDHFVSAKVAAQTNAKSLEPSVSTNPVA---------
----------------
>NZ_ABBE01000764.1|c1|1361-3061|-|ZP_02381196.1|halogenase_PrnC
------------------------------------------------------------
------------MTQNSPANGQDSNH---FDVIILGSGMSGTQMGAILAKQ--QFRVLII
EESSHP----R--FTIGESSIPETSLMNRIIADRYGIPELDRITSFYSTQRYVASS-TGI
KRNFGFVF--HKPGQEHD---------------PKEFTQCVIPELPWGPES---------
-------HYYRQDVDAYLLQA-AIKYGCTVRQKTNVTEYHAD------------------
--KDGVAVTTAQ-----GERF----TGRYMIDCGGPRAPLATKFK----LREEPCRFKTH
S-RSLYTHMLGVKPFDDIFKVKGQR-------WRWHEG--TLHHMF-----A-GG---WL
WVIPFNNHPRSTNN--LVSVGLQLDPRVY-PKTD---ISAQQE--FDEFLARF-PS----
----IAA-QFRDAVPVRD-----WVRTDRL-QFSSSACVG--DRYCLMLHANGFIDPLFS
RGLENTAVTIHALAARLIKAL--RDDDFSPER---FEYIERLQ--QKLLDH-NDDFVSC-
-CYTA-FSDFRLW-----DAFHRLWAVGTILG-----------------QFRLV-----Q
AHARF----------RASRDEGDLDHLD---------------------------NDPPY
LGYLCADMEGYYQLFNDAKAEVE--AVSAGRK-------PAEEAAARIHALIDERDFARP
MFGFGYC----------------------ITGAKPQLNNSKYSLLPAMKLLHWTQTSAPA
EVKR--------YFDYNPMFALLKAYVTTRIGLALK------------------------
----------------
>NZ_AAYX01000016.1|c2|211461-213119|-|ZP_01770174.1|putative_halogenase
------------------------------------------------------------
------------------MSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGMHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----ALTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIDVKPFDACR-EVPKALQQP---VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASACTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WSHYPLW-----NAWFRLWLLTGN-YG----------------QLHLQ-----R
VMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEEAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPERIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NZ_AAHO01000064.1|c1|10459-12117|-|ZP_00439134.1|halogenase_A
------------------------------------------------------------
------------------MSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIGVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASACTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
VMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEAAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NC_008835.1|c3|442203-443924|-|YP_001024264.1|halogenase_PrnC
---------------------------------------------------------MPA
GFPDGFIDEDSTTGWRNTMSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIGVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASACTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
VMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEAAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NC_009075.1|c7|1426594-1428252|+|YP_001062478.1|putative_halogenase
------------------------------------------------------------
------------------MSNNQVRK---YDVVIIGTGIGGTTLGAILARY--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIDVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASACTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
AMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEEAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NZ_CH899760.1|c1|502792-504513|+|ZP_04899514.1|putative_halogenase
---------------------------------------------------------MPA
GFPDGFIDEDSTTGWRNTMSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIDVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASACTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
AMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEEAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NZ_ACKA01000024.1|c1|10394-12115|-|ZP_03790882.1|halogenase_A
---------------------------------------------------------MPA
GFPDGFIDEDSTTGWRNTMSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIDVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASECTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
VMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEEAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NC_007435.1|c1|20115-21773|+|YP_335162.1|halogenase_PrnC
------------------------------------------------------------
------------------MSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIDVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASACTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
VMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEEAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>NZ_ACOJ01000001.1|c3|699867-701525|+|ZP_04521939.1|halogenase_A
------------------------------------------------------------
------------------MSNNQVRK---YDVVIIGTGIGGTTLGAILARH--GLRVAMI
DSGTHP----R--FAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPS-CGV
KRNFGFVY--HRE--------------------HTEQNPQEVNQALVVNEV---------
-------HYFRQDIDAYMLHV-AIRYGCDAYQNTVVDDIRID------------------
--AGGVTVTTRG-----GLTF----EADFVADGAGYRSVLADKLG----LRETPCRAKTH
A-RGLFTHMIDVKPFDACREVPKALQQP----VPWHQG--TLHHLF-----D-GG---WM
WVIPFNNTPESKNP--LVSVGLMLDPRKH-PKPD---VRPEQE--FADFIAKH-PD----
----MAR-QFADARAVRE-----WVSSGRI-QYSASECTG--DRFCLLSHATGFIDPLFS
RGLFNTMQTTNALAGLLIEAA--KDRDFSKAR---FAPVEKLQ--QGLIDF-NDRLVNC-
-SYLS-WGHYPLW-----NAWFRLWLLTGNYG-----------------QLHLQ-----R
VMMKY----------RQTGDARWLEPAD-----------------------ALLPGAFTT
LEPIMRLFEEAAVCVE---------RYGAGEL-------SGEAAERAIYALLEENAALLP
PFFDFV-------------------------SPAERITWPSTPEKIAALLLEWVERLPED
VRAE--------YFDYDVRALLQQPVVKDTITADVA------------------------
----------------
>EF140903.1|c1|1-1752|+|ABO15878.1|halogenase
------------------------------------------------------------
---------MPRSTRPTKPTMNKKPD---TDVVILGSGLAGAALAAVLSRN--GANVLVL
DAGTHP----R--FAIGESTIPYTSMLMRLVSERYDVPEIKYLTTFENVQGKIATT-SGI
KKNFGFLY--HREGDRQ----------------KYHEAHQFPIPRITHIEN---------
-------HFFRQDIDAWMLNV-AVKYGARVQQRTKIVDVSFD------------------
--DAGGTLTDDR-----GNTY----RTRFVVDASGFRSPIAEKLG----LRDTPTRMRHH
S-RSLFTHMVGVANYDDLLPKVSHGHP-----TPWYQG--TLHHLY-----E-GG---WA
WVIPFNNHARTTNP--LVSVGINLDPRIH-PDFD---GTPEEE--FRAFIARF-PD----
----IRR-QFVNATAVRP-----WVRTGRL-QYSSSKTVG--ARWCLTSHASGFVDALFS
RGLSNSFEIINALTWRLLEAL--KDDDFTEER---FEYVQRLE--QGLLDF-NDNLVAN-
-AYTS-FGDYDLW-----DTWFRVWSLGQILA-----------------TFEIN-----S
AYAKF----------LGSHDVRDLARLE-----------------------SIAPDGSIP
AYAPARELMTFVSDRVR--------EVQDKRA-------DPKVAAKEIMAALVKADFVPP
AFG----------------------------LADPDNRWFNASPLKVAETIRWSRNQAPK
DIGA--------IVDEGLTLFIKKRLSPEEFNLTEELKHIVATWPVIGRKLRSPLAP---
----------------
>EF140901.1|c1|18641-20395|+|ABO15852.1|halogenase
------------------------------------------------------------
---------MPRSTRTTKSTKIERPD---TDVVILGSGLAGAAMAAVLSRN--GANVLIL
DAGTHP----R--FAIGESTIPYTSMLMRLVSERYDVPEIKYLTTFENVQGKITST-CGI
KKNFGFLY--HREGERQ----------------KYHEAHQFPIPRITHIEN---------
-------HFFRQDIDAWMLNV-AVKYGARIQQRTRIVDVAFD------------------
--DAGGTLTDDQ-----GRTY----RTRFVVDASGFRSPLAEKLD----LRDQPTRMRHH
S-RSIFTHMVGVPDYDDLLPKVSHGHP-----TRWAQG--TLHHIY-----E-GG---WG
WVIPFNNHARATNP--LVSVGFSFDPRIH-PDFD---GTPEEE--FRAFIDRF-PD----
----IRR-QFVDATAVRP-----WVRTGRL-QYSSSKTVG--ARWCLTSHAAGFVDALFS
RGLSNSFEIINALTWRLLEAL--RDDDFTEER---FEYVQRLE--QGLLDF-NDNLVAN-
-AYTS-FGHYDLW-----DTWFRVWSLGQILA-----------------TFEIN-----S
TYAKF----------LESHDVRDLTRLE-----------------------GIAPDGSIP
SYAPARELMNFVSDQVS--------QVQEKRN-------DAGVAAKAIMEALQKADFVPP
AFG----------------------------LADADNRWFNASTKKVMETIKWARNSAPR
EIGT--------LVDEGLTLFIKKRLSRDEFDLAEEAKHIVAAWPVIGRKFRSPSLSY--
----------------
>NZ_DS570913.1|c1|22968-24605|+|ZP_05017425.1|halogenase_B
------------------------------------------------------------
--------------------------------MILGAGIGGSITGAILARQ--GAKVVLV
DAGQHP----R--FAVGESQNPQLVEWLHILAVRYDVPEIKHLLDIKAVTKYIGAH-HGR
KQSFGFVR--HVPDREP----------------DPREATMFVIPKMLTEAS---------
-------HMFRQDTDTYYFNV-AAKYGCTLRQNWRATDLDFD------------------
--DDGVTVTGQN-----GEVF----RAKYLIDASGFRSPLAQKFD----LRDKPSRIKHH
A-RSMFTHYVGIKPYDDVC-NYPEALRPPAE-SPFHGG--TLHHLI-----E-RG---WF
WIIPFDNHVDSRNP--VCSVGLTFDERLY-PQPKD--MTPDEE--FNHYLDMY-PA----
----VKR-QFEGARRVRE-----WVSTPDRIQYSSKQTIG--DRWCLMSHAAGFVDPLYS
RGLSNTFEVVDALCYRVLEAL--RDGDFSAKR---FEYVERLE--QGLLTY-NDMIVDS-
-SYIA-FSHFRLW-----NAVFRVWACFTTPA-----------------TMRQI-----Q
ARQEF----------MLDGDDRHFREME---------------------NSPYPGLWWPD
SHAFKHLLDVTHETCV---------RYEQGEI-------DGDKAADIVFQAINDCESVNT
PFGW---------------------------KDGEDHRFYRATTPTMIKFMWWASTNGPK
EMRD--------LGRSMLKGVVKSAARGRKVS----------------------------
----------------
>NC_013131.1|c7|3965884-3967575|+|YP_003114298.1|FAD_dependent_oxidoreductase
------------------------------------------------------------
-------MSTIVTATGKAPGEGKVQH---CDVFILGSGLAGSTAAAILQHN--GCNVVLV
DASAHP----R--FAVGESMIPQLVEWLHILAERFDVPEIKNLASIGASTKNIGPS-FGS
KGHFGFMR--HEPGKEP----------------NPKEATQLAIPKVLTQAS---------
-------HLFRQDSDSYMFNV-AAKYGVTTRQYWRAADLDFD------------------
--DDGVTVTGQN-----GEVF----RAKYLIDASGFRSPLAEKYG----LREQPARFKHH
S-RSMFSHYIGIKPFDDVVDHPASVRPP----MRWHNG--TMHHLI-----D-RG---WF
WIIPFDSYKDSTNP--LCSVGLTIDERTYPKNKD---MTAEEE--FNFFLDQY-PA----
----VKR-QFEGAHKVRE-----WVSTDRL-QYSSSRSIG--DRWCLMSHAAGFIDPLFS
RGLSNTFEVINSLAYRILQGM--KDGDFSAER---FEYVEKLE--RGLLQY-NDDLVNS-
-SFIS-FSDFDLW-----NSVFRVWGAFITPG-----------------VMRLT-----R
ARMLF----------LKTGEDKYFQELE---------------------DAEHTGLWWPE
STTVKNMLERTAEICE---------KHEVGEL-------TSKEAANQIMTMVQDCDLINP
TFG----------------------------WKDPEHTFVHPTTFTMAKFMYWASVKSPG
EMHD--------LGREFLKGILKAGRKVRKLL----------------------------
----------------
>AB097904.1|c1|4513-6156|+|BAD38872.1|putative_halogenase
------------------------------------------------------------
--------------------MNRSDQ---YDVAILGSGMAGGMLGAVLARN--GVKVLLL
DAGTHP----R--FAVGESTIPYTSGLTRLIADRYRVPELRALSSFKGIREQVSRN-CGQ
KQNFGFVY--HREGSPQ----------------DWQEINQLVVPSVLRTET---------
-------HLFRQDIDAYLFHV-AVKYGAHPRLGTRIVDVETD------------------
-PDTGAVLRTDG-----GEEF----RAHYVVDGSGFRSPLAEKFA----LRETPTRARTH
S-RCLFTHMIGVEPFDKAPAARRHDQP-----NPWHHG--TLHHVF-----D-GG---WL
WVIPFDNNEHSLNP--LCSVGLTLDPRVH-PKGD---RTPQQE--FDDFLARY-PE----
----IAH-QFRGAKAVRP-----WVSTGRL-QYSAKQVVG--ERFCLTSHAAGFIDALYS
RGLTNTMELVNALGWRLIAAS--KDGDWSMER---FGYLEDLQ--QGLFDF-HDDIVYS-
-SFVG-FRDYELW-----NAVNRTWMLGTMLG-----------------NVMLE-----D
AYYRF----------ERTGDDGVFRELE---------------------EFGHPGSPLPV
SEGFTRMGPLTRELCE---------AVDQGTE-------TSGEAARKILSYIRDADFIAP
SFRFGER-------------------DTRCFAMSPAKMAMNARWCRKDAPPEIGPRMIN-
------------ASKGLVRMRLRAGK----------------------------------
----------------
>EF140903.1|c1|1787-3445|+|ABO15879.1|halogenase
------------------------------------------------------------
-------------------MISKAQR---FDVAIIGAGMGGSMLGAALARN--GVKVLLI
DGGVHP----R--FAVGEATIPYTNVSQRIIAARYNLPELTTLCTLEDCAKTIGPT-FGT
KTHFGFLR--HEQGKPQ----------------NPRETNEFHTPGLLHEAH---------
-------HLYRQDVDAFVFHL-AVQCGCTPLQNWRVADVDFD------------------
--GSGASLHGED-----GSEY----RARYVVDASGFRSPLAQKFN----LRDEIPVYKHQ
S-RSMFTHVYGITHTDDLWPDRKPEYVPP---VPWYEG--TVHHTF-----N-RG---WA
WVIGFDNTPLSRNP--LCSIGLTVDPRVWPKDPN---LSVQED--FDRITGLY-PD----
----IRR-QYEGVTPVRE-----WVSTDRL-QYSSKQTVG--DRWCLLSHAAAFIDPLFS
YGLANTGDAVNKLAWRLIRAC--KDDDFSAER---FDHIEQWQ--QARFHY-NDEIVNA-
-GFTA-FDHFEFW-----KAVFRVWVWGNNYG-----------------TFRAR-----A
GLTKF----------EKDGNDHHFRDLE---------------------KGQYLGYDWPD
HEGFKHLFDTMVANVD---------SFQAGKI-------TADEASEALWDEIEAANFFPK
PFG----------------------------FQNRSVHFMSPKPPVIAKTAVWLMRHGDP
DVRKM-------LLRSGRQAVKLRLTGRKIF-----------------------------
----------------
>EF140901.1|c1|20429-22087|+|ABO15853.1|halogenase
------------------------------------------------------------
-------------------MISKANR---FDVAIIGAGMGGSMLGAALARN--GVKVLLI
DGGIHP----R--FAVGEATIPYTNVSQRIIAARYNLPELTTLCTLEDCTKAIGPT-FGT
KTHFGFLR--HEQGKPQ----------------NPRETNEFHTPGLLHEAH---------
-------HLYRQDVDAFVFHL-AVRCGCTPLQNWRVADVDFD------------------
--GSGASLHGED-----GSEY----RARYVVDASGYRSPLAKKFN----LRDEIPKYKHH
S-RSMFTHVAGITHTDDLWPDRKPEYVPP---VPWYEG--TVHHMF-----N-RG---WG
WVIGFDNTPLSRNP--LCSIGLTVDPRVWPKDPS---LSVQED--FDRITGLF-PD----
----IKR-QYAGVTPVRE-----WVSTDRL-QYSSKQTVG--DRWCLLSHAAAFIDPLFS
YGLANTGDAVNKLAWRLIRAC--KDDDFSAER---FDHIEQWQ--QARFHY-NDEIVNS-
-GFTA-FDHFELW-----KAVFRVWVWGNNYG-----------------TFRAR-----A
GLTKF----------EQDGNDQHLRDLE---------------------KGQYLGYDWPD
HEGFKHLFDTMVRNID---------AFEAGKI-------TADDAAEEMWAVLEEVNFMPK
PFG----------------------------FQDRSVHFMSPKPPVIAKTAVWLARHGDP
TVRKM-------LLKSGRQAIKLRLTNRKIF-----------------------------
----------------
>NC_009142.1|c23|5504029-5505699|-|YP_001107118.1|halogenase_B
------------------------------------------------------------
-----------------MNTQRHSNDKTPYDVAILGTGIGGSMLGAILARH--GAKVLLI
DAGQHP----R--FAIGESTIPYTLLTLRILADRYDVPEIKALATFTDTSRTIGNT-FGV
KKHFGFLL--HHENEPQ----------------DPREVSQFNTPGLLHEAA---------
-------HLHRQDTDAYLFHV-AIRYGCTARQNCRVAEVEFD------------------
--DSGVTLETVN-----GEQF----RTRYVVDASGFRSPLAEKFG----LREDPCRFKHH
S-RSLWNHMLDVTPTDKVLDRPREHRPP----VPWYEG--TVHHMF-----E-RG---WF
WVIAFDNNKLSSNP--LCSVGLTLDERRYPKPTD---ISPEED--FYRHAARF-PD----
----VAR-QYEGAKPARE-----WVSTPRL-QYSSSHTVG--DRWCLLAHAAGFIDPLFS
RGLSNTAEAVNSLSWRLIRAV--KDDDFSAER---FEYVDRLQ--QRLLDH-NDELVNA-
-AFIS-WCDYDLW-----TAVFRAWASGTNAG-----------------SYRLS-----K
AITEF----------AKDGRDEHFMALE---------------------EPPHLGLYWPD
HDGFAKFFESMVSQCD---------LVEQDML-------SPRQAADNIYTQLREADFVPK
HFG----------------------------FAERGQRFINPTPMRFIKTVRWAMREGDP
KLRGL-------IINNAKEALKARVKGQKLY-----------------------------
----------------
>NZ_AAMY01000003.1|c1|117999-119246|-|ZP_01045314.1|hypothetical_protein
------------------------------------------------------------
-------------MAAAPLLDPAWTT---WDVVIVGAGPAGAATAITLANC--GQRVLLV
EKRGSP----S--FKLGESLPPAS---------------IGLVRHFLGDPESPDQQLPGL
FRTAGNIA--LWGNEQAE---------------ITDFFFT-----PTGHGL---------
-------CVDRLAFDEALCTK-AIAAGATLLRDVRFQSCTRI------------------
-ESGNFNWQLTLTSRAGIRQV----RARYLVDCSGRQAVVARMLG---VPRLYQ------
G-DRLFAY------------AQWFSCS-GGD-DDRYTR--I--EAT-----P-HG---WW
YSNRL----PGSGGN-ETRRLVVLHTDKDLPAARL--AASRQG--FDQLLDGS-TH----
----IALLLKARGYRSCG----SIRGAPAH-SQRLRDFCG--DAWMAVGDAAQAYDPLSS
QGIDKALRTASHAGHMIHYAL--TDSSQGATGLDGRNPYIHRY--DQEQHRLWQAFSSQR
NFYYG---VQTRW-----SDQV-FWQRRR--------------------QPANE-----S
SQFST----------DETEPGGNGAI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_010296.1|c3|2504779-2506575|+|YP_001657790.1|hypothetical_protein
------------------------------------------------------------
------------------MVTTDTKV---YDVVIMGAGFAGVCQARHLLLNVPNIKIALI
DPRPEERTNKD--LKIGESMVEIA---------------TLFVCKELGLYEYMIEN---H
PPKFGLNF--HWPKKKDKTTT------------TDDYYHIWNNRQPPLASF---------
-------QMNRAKFERDLLKM-NKAMGATFYQG-RVVDVDLT--------------SKDE
LKTVIAKVENEQ------ITL----KAKHVIDAAGRKFIIGQKTD---NLLFGADNLFGL
DTGSVWVRVNNIDRTIFHDGYDPYGTT-----CSHYYA--TNHWFG-----H-GH---WL
WMIPTE------KDSQEISIGIAYHRSAI-ADKQ---INTKEK--FYAFLKANHEI----
----LYR-LVNSGENID------FHYLPRP-SHTSKTMFSA-DNWYVIGDAACIFDPFYS
LGSSMISYQIECTTEIIRSKL--VGEAIGEKKQAAYNDFILTY--TRFNNHLIKHHDQQ-
-LGDASIMSWRIY-------HDYIWWFGVQVPMYTGKWFL---------DLDFL-----T
RYTPG----------LKEHQMGYCEHLY-----------------------QQFNEVIAQ
GKNLGFMDCHRGDQLWGDYHTLKHFDDFVENA-------KLEPRRCNVFACMKTTNFYTA
IWYANFLWKG----------------FGVTAFVKPKNLFYLLKHLQGVIQADIAERVYKH
FTKGIPSNRKIAEMRQEFTTYHYQPELNSWEQETAPLASQKITVTV--------------
----------------
>AM778943.1|c1|91233-92996|+|CAO88202.1|
------------------------------------------------------------
------------------MNTTQALH---YDVVIMGAGFAGLCQARHLMLNIPNIRVALI
DPRPENRPDTD--LKIGESTVEIA---------------ALLICKELGLHDYMIEN---H
PPKAGLNF--HWPKNPAETDS------------IDDYYHVWINRQPPIPTF---------
-------QINRAKFERDLLKM-NKEMGAIFYNG-RVVDVDLT--------------EGDQ
LKTVTVKLEDTT------IEI----TAKHIVDAAGRRFIIGKKTD---NLIFGSDQLLGV
NNGSAWVRIKDVDRTIFHSGYHPAGTT-----VSHYYA--TNHYFG-----P-GH---WL
WMIPID------RDSKELSLGVIHHHDVI-PAAT---INTQEK--FTAFLKANHTV----
----LYK-LLQNSELVD------FHYLHRV-AHKSKVMFSP-DNWYVVGDSACIFDAFYS
LGTTMIAIAVESITEIIRAKL--TNEANAEEKRAVYNDFNLAF--TDSVNTFMQEHQKQ-
-LGHASIMSWRIY-------FEYMWWFGVLVPMYIGKWHL---------DPAFL-----K
QFTGP----------FRTFLNGLFVDVY-----------------------QDCNQLVER
GVNMGLMDAIRADQLIGSYYTFKHFEDFLENS-------KLEPQRCNIFTSMKNTFFYVA
IWYAMFQWKG----------------FGWRGLLKPRNLAHFSYLLAQSGLSALGEMQHNF
LTRSLPDNSEIEEMRQEFKEYRYQGKLQPWSAELS-------------------------
----------------
>AM778943.1|c1|93089-94852|+|CAO88203.1|
------------------------------------------------------------
--------------------MTQDKE---YDVIIMGAGFAGLCQARHLMLKIPNIKVALV
DPRPEQRTDKD--LKIGESTIEIA---------------ALFLAKELGLHDYLIEN---H
APKQGLNF--HWPKNPAKTET------------IDDYYHAGSNRQVPIPSF---------
-------QINRSKFEQDLLKM-DKAMGINFYNG-QVVDVDLT--------------PGDA
IKTVKIKVGDER------MEL----QAKHVIDAAGRKFIIGRKTD---NLLFSPENLMGL
NTGSAWVRVKNVDRTIFHSGYDPLNAS-----TSHYYS--TNHYFG-----E-GH---WL
WMIPID------TQTMELSIGVIHHHDVI-NSTQ---VNSREK--FHDFLRNNHQI----
----LAN-IIDSGEAVD------FHYWPRI-SHTSKTLFSP-DNWYVLGDAAYIFDAFYS
YGTTTIALAIEGITEIVRAKL--AGEADAEQKRAAYNEFNLAY--SRSVNCLYRGHAKQ-
-LGQASVMSWRIY-------FEYMWWFGVQVPMYVGKWHL---------DLTYI-----P
IFLKT----------LNSNIDGLFADLN-----------------------EQFTELADK
DVNIGLMDCYRGDQLFKGYHTLKHFDDFLENT-------KFEPRRCNVFAGLKATCFYAA
LWYALFQWKG----------------FGIQGCLNPRHIYHFLRLLGLSGQATIGELIYKF
KTKGLPANSEIEAMRQEFKTYQYQPKLQPWLAEATNS-----------------------
----------------
>AM778943.1|c1|94938-96746|+|CAO88204.1|
------------------------------------------------------------
----------------MNYTITQSRE---YDVVIMGAGFAGLCQARHLMLNIPNIRVALI
DPRPVERTDKD--LKIGESLIEVA---------------ALFLCKELGLHDYLIEN---H
PPKSGLNF--HWPKDPAKTET------------LDDYYHVWANRQTPVGSF---------
-------HLQRAKFEQDLLVM-NCQMGADFYEG-RVKDVALT--------------SGDE
LKTVYAKVGEEN------ITL----QAKHVIDAAGKNFIIGRKTD---NVLSGPENLLGL
NNGSAWLRVKNIDRTIFHSGYHPEGAS-----TSHYYA--TNHYFG-----Q-GH---WL
WMIPID------KHSMELSIGIIHHHDVI-PAQS---INNLEK--FSNFLKSNHTI----
----LSR-LIESGEVVD------FHYWPKI-AHKSKVLFSP-DNWYVIGDAAHIFDAFYS
YGTTMIAFEVESVTEIIRAKL--AEEAAAEQKRSAYNDFNLAY--ARTVNCLYRDHAYQ-
-LGHASVMSWRIY-------FEYMWWFGVHVPTYIGKWHL---------DLNFI-----P
RYVTI----------ADGNVNGIFADLC-----------------------REFHQLVSQ
GANIGLMDAYRADQLLGGYGTLKHFDDFLENT-------KFEPRRCNVFASMKAAYFYIA
IWYALFQWKA----------------FGIAGWLNPKHWYYFGRMLKLSIQATIAEVIYKR
KTRGIADNSQIEKMREEFKNYHYQPQKKSPSVVQNVVGERVTIESFPA------------
----------------
>NC_009953.1|c16|3641729-3643483|+|YP_001537957.1|tryptophan_halogenase
------------------------------------------------------------
------------------MGREIGSE---YDVVVMGGGPAGSTLGALLARR-TTLSVAIF
EKEEMP----R--EHIGESFAHQ----------------MIPAIEQSGALEKVLAS-KCW
VKKYGGVF--NWGEVPMV---------------AFFDHRNYLNDGVPRFAM---------
-------HVNRAEFDHILLQH-AADSGVKVFEDTPVKQFESH------------------
--ADGCTITLGD-----GTVV----RSKYFVDASGRRNSIAAKQR-----REWLSTYR--
N-IAIWQHFLGGERVQDLPGDWNI--------FREGNQSPIGCFAF-----Q-DG---WC
WYIPVPKIIDGKRRL-TYSVGIVTIPEIL-KQTGSD-FTDQKT--FIDTIRRV-PY----
----LKD-LIADAEPIAD----KMLTATNY-SMVNGRFSDYDERWLLVGDSAYFVDPLFS
SGVAFATNQAVNAAMLLEHTL--TGELNEQGCRDLWRDYDEGW--HGMAET-FALSIDQ-
-WYHALGGQ---------DPESIYWRHRSSSPDLDIQERTFDVLLNTSVTPNLM-----Q
LITGAPMQGEGP---LTRANERAEPAAI-----------------------DVDATLTLA
PGVVVRETVGLDVPGF---------KGHLPPP-------PFDDEVSEATKAGIATYWADP
VTNRDVI-------------------ESPSALPVPAHRIGFADGAIDVEIRGLAREGTAE
LLGYLAAGVTMRKLDGQLTMSQHQLLKRLVRAGLVVAAG---------------------
----------------
>NC_008095.1|c2|1501578-1503392|+|YP_629542.1|tryptophan_halogenase
------------------------------------------------------------
-MFPVRPLQSNGCVRCMELLMSGAWEGKLYDVIVMGGGPAGATLAARLRKD-PGLSVAIF
ESERFP----R--EHIGESFVPS----------------AVSSLQESGALGRVLSS-DCW
IKKGGGYY--SWDAVRPWS--------------TFFEHKAYERDGYRRWAF---------
-------HANRAELDDILLRH-AEENGAEVFEGTPVKQVY--------------------
-RRDGFTEVDLG----EKGSA----RCKVFVNASGRYSV--TSLG---GPREFLSSYR--
N-IAIWSYIRKGKPAQSLPGDWNI--------FRESGVSPIGSFAF-----E-DG---WF
WYIPIPLEVDGRREV-VHSLGLVTDPRGLKSKRD---YMSPSV--FMETARKV-PF----
----LCD-LVADAELIYD----EFRTTANY-SRISHQMCSWENREIRVGDAAFFVDPLFS
TGVHFALHHTAAAAVLVRAAF--DEAMPEQHREDLWHDYDQML--RKQAQV-FSLAIDQ-
-WYNEISLAHPGSVYWRERSERATFEVRNATFHYLV-------------NGSLD-----E
DLLHV----------ISQGNDAVEALSE--------------------------TGAWRT
SFAQLQRLRPADDALVQLMPNVKFRQSVTLEH-------PIADSAEDKLDARPQAFDHGP
YWESPERHAHEV--------------APRFGRPSPCLRFYFEDGDHQDTVRILWNRPNSA
LLERLSQPHAYGPLLAGCSLSERGLLDQLLLKGMMRVIP---------------------
----------------
>NC_008596.1|c15|6816577-6818328|-|YP_890976.1|halogenase
-----------------------------------------------------MRAQISH
LDPTTREALATRIRNQLSRADATSTD---HDVAIVGGGAAALTLALQLRRERPGTRVVMI
APEVRPVPEMT--HTVGESTVEIS---------------AHYLRDRLDLADHLNTA---Q
IRKMGLRMFFSHNGNTD----------------ITERMELGGSSFVPQVTY---------
-------QIDRGRLENELHRR-CVAAGVQVLCG-RVRSVDLT------------------
--TRTLTYQCDD----ATATT----TARWIVDASGRNRLLGRELD----LKRTTGHHC--
N-AAWFRVATEIDVGAWSDDPAWQGRL-----VEGERAMSTNHLMG-----D-GY---WV
WLIRL-------ASG-ATSVGIVADPDHH-AFDRF--NTLDKA--KAWLREHE-PQ----
----CAAVLADHEHQIRD-----FRVMKHY-SHGAAKVYDGRERWCLTGDAGIFLDPLYS
SGLDLVAIGNGLIADMITRDL--DGEDVSARA----QISDTLY--RSLTDM-WLRVYQD-
-QYTL-MDTPAVMSAKIIWDVAFYWGFIGLLYM----------------NNRYARVADDP
EFVPQ----------LEGLIALSNRMQS-----------------------FFREWAAVE
DRATTVPFVDLYAPL----------NFMVSLH-------TAMAEPSVDFTGQFATNATVL
RQLAGQLAETVLAHK-----------ASRFDDDGVVRMVQAWQRDSLLRDLRATYRREQA
------------TNPLSSDWIITASPALATG-----------------------------
----------------
>NC_013440.1|c7|1723770-1725500|-|YP_003265760.1|monooxygenase_FAD-binding_protein
------------------------------------------------------------
---------------------MSLQS---YDVVILGGGLAGLALSVQIKLRNSDISVLIL
EKRKESAPDAA--FKVGESTIETS---------------AEYFARVIDCREYLNTQ---Q
ITKPGLRFYFSAGDNSD----------------IARRVEIGHGTYPKYLEY---------
-------QLDRGRFENHLGEK-TTGMGSVLIQGATVTDISID------------------
REGHEVMYRHEG----EEHTV----QCKWVVDATGRRGLLKRKLK---LEKKLDHPIN--
--ATWFRVKEKVDISNWSEEKEWQDKPEIQG-LRWPA---TNHLLG-----N-GY---WV
WLIPL-------ISG-STSIGIVADERIH-PLNTF--NSFDKA--MAWLAENE-SQCHEK
VLRALARSKLEPNTDVDENGLMDFHVLKQL-GYDCEQVYSG-DRWCLVGEAAAFNDPFYS
PGGDLIAHGNSYTTELIVRNM--AGEDITERA----EKYDNMY--LKFFFGSLQTVYRD-
-QYEV-MGNAQVFTAKVTWDYFAYWCTVSLLFF----------------QNKLQD----L
EFLSL----------IQDELDKYWVLNG-----------------------KVQEFFVQW
NRLDPEERTDKYVDQDAMDLLNKVHNELGEPL-------TDAELVERFRENMRLLEELAR
QLYQ----------------------RASLSIPEHPETRTIDPYQISLDPRLWKEEGFFK
ETPTPDLAMKL-NKELEEIWLPRASERAA-------------------------------
----------------
>NC_008392.1|c2|455620-457167|-|YP_777807.1|FAD_dependent_oxidoreductase
------------------------------------------------------------
------------------------ME---ADVAILGGGLAGLSLARQLRLEKPDIRIVVL
ERGKRPAQEAS--YKVGESSVEVA---------------AHYYGERLKLKAHIDEA---Q
LPKLGLRFFFPHGDNSD----------------VTQRLEIGPSDYPTVPSY---------
-------QLDRGRFENFLHDQ-VLADGVTVFDRARVQRVELR--------------PG--
-ELHEIGFVHGD----EVKTV----TCRWVVDAAGRSKILKRKLD-----LEKDGNLR--
N-GAVWFRLGAEVDISEMSDDPDWLARTG---PSRRFS--TNHFMG-----P-GY---WV
WFIPL-------GSG-STSVGIVFDNTMH-NVKEM--NSFEKS--MEWLRRNE-PQ----
----CADMVERYRDTLQD-----FLCYQDY-SYSCKQVYSA-DRWCITGEAGVFIDPFYS
PGSDFIAYSNEFVGDLILRDL--RGEDIAPLA----RAYDRVF--LQLAEV-VFMLYEG-
-LYPK-FGNGFVMTQKILWDSVIYLGVTCLLYF----------------HHKWHD----L
AFLGR----------IDNELARYNDLLR-----------------------SVAD-----
-------------------------HFKRQPI-------LHDASLAGEYVDLTKTFLFGR
NLNQELL----------------------IEHPDDDALIAKLRENIGLLEELAVSIHNNV
------------DISRNLQPLRAAEPA---------------------------------
----------------
>AM778955.1|c2|170037-171020|-|CAO90435.1|
------------------------------------------------------------
------------------------------------MGLVNSFIHRLYQYW---HCDTVT
RQDIHP----LKNYHNYELAFQWL---------------RENEPVLAAHLEGKSPE--DF
RKMPKYSY--SSKQ-------------------VFSFNRWTCVGEAGLFPD---------
-------PFYSPGSDSIGFGNSLTTQMIELDLKGQLTPERVD------------------
-DANHFYLTYHD-----GLTF----NIQNSYNCMGNGIVLSTKFI---------------
-----WDTLAG-----------------------------------------------WT
FS------------------GLMMFNSIF--------LDPELKMKVQQINAEFFPL----
-------------------------------SYRMQQLFR---DWA---------NQSLG
R---VSFEFIDYLAIPFVNEL--RTRNLQSNK--TEAEITEAY--RASLKL-LEEFAQVI
FQIALEDTSPELLPKINEHPWLNAWAISLD-------------------ASKWE------
---------------TDGLFSPKSEPRN--------------------------------
-------------------------LHIIKKQ-------YLEAINR--------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>FJ609416.1|c1|4610-6487|+|ACM68683.1|AerJ
----------------------MKTVEFLSDLNHLGVTIWMEGDKLRYRSPQGVMTPDLL
EQLKEHKEELIVLLREQADNFSSETD---YDVAICGGGLAGLTLARQLKLKQPNLSVVVL
DKMARPLPEAG--FKVGESTVEVG---------------AFYLANTLQLTDYFNNQ---H
LSKLGLRY--FFKPQETE---------------FHKRPELGLSEFHAPKSY---------
-------QIDRGKLENDLRQF-NIEAGIDLKENCSVKDIEFA---------------EGL
QQQHKIIYTQGSGANQKTHCI----KSRWVVDAMGRRRFIQKKLG---LAKPNHNNY---
--SAVWFRVEGRFDVSNFVPASEEKWHRRVPNNNRYYS--TNHLCG-----E-GY---WV
WLIPL-------STG-YTSIGIVARQDIH-PLKNY--HNYELA--FQWLRENE-PV----
----LAA--HLEGKSPED-----FRKMPKY-SYSSKQVFSF-NRWACVGEAGLFPDPFYS
PGSDSIGFGNSLTTQMIELDL--KGQLTPERVDD-ANHFYLTY--HDGLAFNIQNSYNCL
KNGTA-MATKVIW------DTLAGWTFGCLMMFNSIFL-----------DPELK-----M
KVQQI----------NAEFFPLSYRIQQ-----------------------LFRDWANQS
LGRVSFEFIDYLAIPFVNELRT---RNLQSNK-------TEAEIIEAYRASLKLLEEFAQ
VIFQIAL-------------------EDTRPELLPKINEHPWLNAWAISLDASKWETDGL
FSPK--------SEPRNLHSIKKQYLEAINR-----------------------------
----------------
>AM778955.1|c2|170960-171919|-|CAO90436.1|
-----------------------KTVEFLSYLNHLGVTIWMEGDKLRYRSPQGVMTPDLL
EQLKEHKEELIVLLREQADNFSSETD---YDVAICGGGLAGLTLGRQLKLKQPNLSVVVL
DKMARPLPEAG--FKVGESTVEVG---------------AFYLANTLQLTDYFDHQ---H
LPKLGLRY--FFKPQETE---------------FHKRPELGLSEFHAPKSY---------
-------QIDRGKLENDLRQL-NIEAGIDLKENCSVKDIEFA---------------EGL
QQQHKIIYTQGSGANQKTHCI----KSRWVVDAMGRRRFIQKKLG---LAKPNHNNY---
--SAVWFRVEGRFDVSNFVPASEEKWHRRVPNNNRYYS--TNHLCG-----E-GY---WV
WLIPL-------STG-YTSIGIV-------------------------------TL----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>AJ269505.1|c1|31507-33384|+|CAC01605.1|putative_halogenase
----------------------MKTVNFLSHLNDLGINVWVENDKLRYRSPKGVIIPELL
QELKERKEELIAFLRQQAEDLNQAET---YDVVICGGGLAGLTLARQLKLQKPNMAIAVL
DKMSGLSPEAS--FKVGESTVEVG---------------AFYLANTLQLTDYFEEQ---H
LVKLGLRY--FFNNSATN---------------FQERPELGLSEFHAPNSY---------
-------QIDRGKLENDLRQF-NMEAGVELREGCLVNEIALA---------------EGL
QQHHKVVYTQGDGDNRKNKII----KARWVVDAMGRRRFLQRKLG---LDKPNNDNF---
--GAVWFRVNGRFDIGDFVPSSEEKWHNRVPNKNRYYS--TNHLCG-----E-GY---WV
WTIPL-------STG-HTSIGIVAPQDIH-PLKNY--YNHELA--YQWLQKNE-PV----
----LAC-HLKDKEPED------FRKMPKY-SYSSKQVFSS-NRWACVGEAGTFPDPFYS
PGTDNIGFGNSLTTQLIALDL---EDKLTKEKVEDANYFYISY--SDGVTLNIQNAYNC-
-LGNGIVMATKFI-----WDTLSGWTFSGLMMFNSIFL-----------DQDFR-----T
RVQEI----------NSKFFPLSYRMQQ-----------------------LFRDWANKS
LNRVNFEFIDYLAIPFVDELRT---RNLKSNK-------TKSEIIENYLSSLKLLEEVAQ
VMFHLAL-------------------EDTMPDMLSKVNSNSWLNAWAISLDISKWEADGL
FTPK--------SEPRNLNLIKQQLWEAIGK-----------------------------
----------------
>DQ075244.1|c1|24728-26605|+|AAZ03553.1|McnD
----------------------MKTVEFLAYLNSLQINLWAENDKLRYRSPQGVMTPELL
GKLKERKEQLIALLRQKAEDLGEAEV---YDVVICGGGLAGLTLARQLKLQKLNISVIVL
DKIARPLPEAS--FKVGESTVEVG---------------AFYLANTLQLTDYFEEQ---H
LVKLGLRY--FFNNSATN---------------FQDRPELGLSEFHLPNSY---------
-------QIDRGKLENDLRAF-NVEAGVELRENCLVNEIELA---------------VGL
QQHHKIVYTQDKGDHKKTNVI----QARWVVDAMGRRRFLQKKLG---LDKPNNAQF---
--GAVWFRVEGRFDISDFVPSSEEKWHNRVPNKNRYYS--TNHLCG-----E-GY---WV
WTIPL-------STG-HTSIGIVARQDIHPLKTY---YNYELA--YQWLQKNE-PT----
----LAF-HLADKQPED------FRKMPKY-SYSSKQVFSY-NRWACVGEAGTVPDPFYS
PGTDNIGFGNSLTTQLITLDL--EGKLTQEKVKD-ANHFYLSY--SDGVTLNIQNAYNC-
-LGNGMVMATKFI-----WDTLSGWTFSGLMMFNSIYL-----------DQEFR-----T
KVQQI----------SSKFFPLSYRMQQ-----------------------LFKDWANQS
LHRVNFEFIDYLAIPFVEELRSRNLRYNQTES-------EIIENYLSSLKLLEEVAQVMF
HLAL----------------------EDIMPEMLPKVSSNSWLNAWAISLNASKWESDGL
FAPK--------SEPRNLDLIKQQLWEAIGK-----------------------------
----------------
>NC_005027.1|c1|202881-204269|+|NP_863882.1|alkylhalidase
------------------------------------------------------MSAQQP
FGYTRRLLTLQFPIELPLSNMSTPKMKDFYDCVVIGGGPAGGAAASIVADS--GVSTLLI
ERDPVP----R--FHVGESLMPE----------------CYWPLERLGLIDQVKRS--GW
QAKKSVQFVTHTGKE------------------SAPFFFREHDERECSTTW---------
-------QVERSEFDKMLYDR-ASELGADCFDQTRLIDVQTE-----------PGETEDQ
PIARAVVVRTAD---GTEKTI----GCKVVVDATGQQAFLAGKMG----LKEINPDLK--
K-AAIWTYYRDAVRGE----------------GDNDGATIILNTKS-----R-DS---WF
WFIPQ-------SRG-ITSVGCVGDNDYL-LKGR---GTPEEI--FEEELANC-PG----
----LQP-RLANATRVGK-----ITTAKEF-SYMTRRHSG--PGWVLIGDALGFIDPVYS
SGVYFALEMGVRAGDAIVEGL--KKDDLSAEQ---LGKWTDDF--KEGASK-VRQLVHA-
-FY---------------NKDFSIGRFMKE-------------------HPEYR-----G
NVTDL----------LIGRVFHEDAGK---------------------------------
-------------------------MFPALDR-------SIEMARADAMSKADSMAETKP
MST---------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ABCS01000022.1|c1|28163-29446|+|ZP_01907891.1|putative_halogenase
------------------------------------------------------------
-------------------------------MVIIGGGPAGTSAATQLAKK--GYDVVLF
EKAKHP----R--EHVGESLIPH----------------FWRYTDELGVSEKILAE--GF
QEKTGGTV--VWNGRIQ----------------QVSFSDFAYDRRAL-------------
-------HVERARFDHILFQH-CQENGAKTFERVMVKSVRFA---------------EEA
GGKQTVVWRDID--AATDGEI----ECEFVVDASGQASVLGRQLD----IWEIDEDFR--
F-VSLWGYFKGAKYVALDGKAHPFE-------KSREIKPTTFVTAL-----K-DGDGAWS
WLWHI-------TMRENTSVGLVISREEL-ARAKANYESLEAY--YRETCSTT-PI----
----INQ-LLEDATYEGE-----FSAIRDF-SYRVKQAAG--PGYLMIGDAATFIDPVFS
QGIVLAFYTANLASWAIDRAM--KRPEDTERT---MAMYSHQLLMRADMAR---SMALP-
-SYMP-------------PEVSEAGRTAVGF------------------ESKQE-----Q
KLMRV----------AAGLTNRSQNFH---------------------------------
-------------------------TLVGGQE-------DEEDTIKILESIEF-------
------------------------------------------------------------
------------------------------------------------------------
----------------
>NZ_ACFA01000763.1|c1|22277-23623|+|ZP_05542402.1|alkylhalidase_PltA
------------------------------------------------------------
---------------------MSDFD---YDIGIIGGGPAGSTMASYLAKA--GISAIVL
ESAEFP----R--PHVGESLVTAT----------------TPVLQEIGALAKVDAA--GF
PKKYGAAW--TSAAKETVPEMGFTGMTQGFRLASVEFQERDQPGVDQAYTY---------
-------HVDRGKYDQLLLQH-AAELGARVRERTRVQDVEFT------------------
--DDGVVLTAVG--DEGTERL----RVRMVVDASGRQTMLGRKKK----LKVPDPVFN--
Q-YAIHAWFDGLDRKALAD-------------DPEQEDFIFIHFLP-----VSDT---WV
WQIPI-------SET-TTSVGVVTQKAKV-KSSG---QEREEF--FWECLGTR-PE----
----LRA-ALEKAERVRE-----FKTEGDY-SYGMKEVVG--DRWALIGDAARFVDPIFS
SGVSVAMNSARLLAKDIVSAV--ERDDFSKKS---FGDYERVL--RRGVSS-WYEFISI-
-YYRL-------------NILFTAFVQ----------------------DPRYR-----L
DVLKM----------LQGD-----------------------------------------
-------------------------VYGEEEP-------KALTRMREIVRRVEEN-----
----------------------------------PDHLWHPYLGTLRAPAAAPLF-----
------------------------------------------------------------
----------------
>NC_004129.6|c3|3092974-3094323|+|YP_259893.1|alkylhalidase_PltA
------------------------------------------------------------
---------------------MSDHD---YDVVIIGGGPAGSTMASYLAKA--GVKCAVF
EKELFE----R--EHVGESLVPAT----------------TPVLLEIGVMEKIEKA--NF
PKKFGAAW--TSADSGPEDKMGFQGLDHDFRSAEILFNERKQEGVDRDFTF---------
-------HVDRGKFDRILLEH-AGSLGAKVFQGVEIADVEFL------------------
-SPGNVIVNAKL--GKRSVEI----KAKMVVDASGRNVLLGRRLG----LREKDPVFN--
Q-FAIHSWFDNFDRKSATQSPDK---------VDYIF---IHFLPM-----T-NT---WV
WQIPI-------TET-ITSVGVVTQKQNY-TNSD---LTYEEF--FWEAVKTR-EN----
----LHD-ALKASEQVRP-----FKKEADY-SYGMKEVCG--DSFVLIGDAARFVDPIFS
SGVSVALNSARIASGDIIEAV--KNNDFSKSS---FTHYEGMI--RNGIKN-WYEFITL-
-YYRL-------------NILFTAFVQ----------------------DPRYR-----L
DILQL----------LQGD-----------------------------------------
-------------------------VYSGKRL-------EVLDKMREIIAAVESD-----
----------------------------------PEHLWHKYLGDMQVPTAKPAF-----
------------------------------------------------------------
----------------
>AY394844.4|c1|2808-4157|+|AAQ90172.1|putative_halogenase
------------------------------------------------------------
---------------------MGDYD---FDVGIIGGGPAGSTMASYLAKA--GISCAVF
EKELFE----R--EHVGESLVPAT----------------TPVLLDIGVMDKIEKA--NF
PRKFGAAW--TSADSGPEDKMGFQGLDHDFRAAEILFNERQQEGVDRDFTF---------
-------HVDRGKFDRILLEH-AGSLGAKVFQGVEVADVDFV------------------
-KPGDVRLNVKL--GNQKVGI----RTRMVVDASGRHVLLGRRLG----LREKDPVFN--
Q-FAIHAWFDNFDRRSATRNPDK---------VDYIF---IHFLPL-----T-NT---WV
WQIPI-------TET-ITSIGVVTQKQNY-TKSG---LSYDDF--FWEAVKTR-EN----
----LYD-ALKASEQVRP-----FKKEADY-SYGMKEVCG--DSFVLVGDAARFVDPIFS
SGVSVALNSARIASKDIIAAV--RNNDFGKAS---FAEYEGMI--RNGIKN-WYEFITL-
-YYRL-------------NILFTAFVQ----------------------DPRYR-----L
DVLQL----------LQGD-----------------------------------------
-------------------------VYSGERL-------KVLDKMHEIVATVESD-----
----------------------------------PDHLWHKYLGDMQVPTAEPAF-----
------------------------------------------------------------
----------------
>NZ_GG753626.1|c7|4839331-4840686|-|ZP_06710469.1|FADH2_dependent_halogenase
------------------------------------------------------------
------------MRAGQGDRAMSATD---FDIAVIGGGPAGSTAASYLARA--GLSVIVL
ESDTFP----R--PHVGESLVPAT----------------TPVLLEIDALDKIDEA--GF
PRKYGASW--TSAESRDIPRLGFSGLQHDWTA-DIQFVERDQKGVDRDYTY---------
-------HVDRSRFDAILLRH-AQEQGASVVNGARVLGVDFG------------------
--DPEVTVRTRI--AGKEMSY----TVGMVVDASGRQTMLGRQLR----TKVSDPVFD--
Q-YAVHAWFEGLDREALSTS------------AAQAEHIYVHFLPI-----K-DS---WV
WQIPI-------TDK-ITSIGVVTQKKRF-KEGS---GDLDDF--FWEFVGSR-PE----
----LYD-ALKGCRQVRP-----LKAEGDY-SYSMKEITG--DRYVLIGDAARFVDPIFS
SGVSVALNSARIASQDIIAAH--AAGDYGKDR---FAGYESKL--RRAVKY-WYEFISI-
-YYRL-------------NVLFTAFVQ----------------------DPRYR-----K
DVLKM----------LQGD-----------------------------------------
-------------------------VYDDEEP-------KALIAMREAVAAVEAN-----
----------------------------------PDHLWHPYLGTLKASG----------
------------------------------------------------------------
----------------
>EF140901.1|c1|46328-47671|+|ABO15865.1|halogenase
------------------------------------------------------------
----------------------MDAE---FDIGIIGGGPAGSTAASYLAKA--GLKVAVF
EAETFP----R--EHVGESLVPAT----------------TPVLIETGAMPKVEAA--NF
PKKFGAAW--TSAEDRNIDHNGFRGLTHDFRAAEILFNERDQDGVDRDYTF---------
-------HVDRGKFDQILLQH-AESLGAKVFHGIRIGKVDFD----------------GE
MPVLEAKIGSKS------VDI----PVRMVVDASGRQTRLGNQLK----FKVPDPIFN--
Q-YAVHSWFDNFDRKALAVNKDQ---------ADYIF---IHFLPV-----T-DT---WV
WQIPI-------TDT-ITSIGVVSQKKRF-QEFA---GDREKF--FWDTVASR-PE----
----LLD-ALKNSDQVRP-----FKTEGDY-SYGMSQIAG--DNFVLIGDAARFVDPIFS
SGVSVALNSARLACKDIIAAA--EAGDFKKER---FGTYERKL--RKGVSN-WYEFIQI-
-YYRL-------------NILFTAFVQ----------------------DDRYR-----L
DVLKM----------LQGD-----------------------------------------
-------------------------VYDDEEP-------KALAAMREIVKAVEDD-----
----------------------------------PTHLWHPYLGSLKAPSAKPQF-----
------------------------------------------------------------
----------------
>DQ116941.2|c1|10544-11893|-|AAZ77674.1|ChlB4
------------------------------------------------------------
----------------------MQPD---FDAAIVGGGPAGSAMASYLAEA--GLSVAVF
ESEMFP----R--PHIGESLVPAT----------------MPVLDEIGVMPDIEAA--GF
PKKYGAAW--TSAESRDVPHNGFTGLDHDFKAAEVMFVERDQPGVHRDYTF---------
-------HVDRGKFDLILLKH-AESRGAQVFQKTRVLKADFD--------------TDPD
LVTLNCRLGPRT------LDF----TTRMVIDASGRQTMLGNQLK----VKVPDPVFN--
Q-YAIHAWFEGLDRTAMALDPAK---------RDYIY---VHFLPL-----E-DT---WM
WQIPI-------TDT-ITSVGVVTQKHRF-KAAS---ADREKF--FWDIVSSR-KD----
----IYD-ALQKAERIRP-----FKAEGDY-SYAMRQICG--DRFLLIGDAARFVDPIFS
SGVSVALNSARLAAKDVIAAH--RAGDFRKES---FATYEEKL--RRAVRN-WYEFISV-
-YYRL-------------NILFTAFVQ----------------------DPRYR-----I
DVLKM----------LQGD-----------------------------------------
-------------------------FYDGEEP-------KALKAMRDLVTKVEND-----
----------------------------------PEHLWHPYLGTLRAPSAAPTF-----
------------------------------------------------------------
----------------
>NZ_GG657738.1|c16|6383116-6385086|-|ZP_04609040.1|alkylhalidase_cmlS
MRGHQTEGRTDPDGRSEARAGISFRQGRTVQDPIEGHGGRLHRDVGPPEEDTVPTRKQRG
VNGVDRYRDQPQEVFVSPYTEIRECEMARSRVAIIGGGPAGCVAGLTLHKL--GHDVTIY
ERDRFP----R--YRIGESLLPGT----------------MSILNRLGLQERIDAE--DF
VKKPSATF--LWGQDQAPW--------------TFSFAAPKVAPWVFDHAI---------
-------QVKREVFDNLLLDE-ARSRGIAVLEETPVTGVDLS------------------
-GADGVALTIRQ--DGKATRV----ESDFVIDAGGSGGPLVRQLG----VRRYDEFYK--
N-FAVWSYFQRKDPFE----------------GDLKGT--TYSITF-----E-DG---WV
WMIPM-------KGD-LYSVGLVVDRTKS-AEVRQ--LGADAF--YRSTLAKC-GK----
----AMD-LLAGAKMVDD-----VRIVHDW-SYDTEVFSA--DRFFLCGDAACFTDPLFS
QGVHLASQSAVCAAAAIDRIT--HNKDETDAV---HAWYNRTY--REAYEQ-YHEFLAS-
-FYTFASFTEPDS-----EFWRKRRISESD-------------------DERLSRR---K
WFEKLARDGQDSGVTLDGFRDRASTMISIGRHQRQQLSDEFSEAELNAARVRWISDLTAR
LNSITRLRWTGSKAILKPYYRVDALSFRLEPR-------EILSNEDDLDMNQYPLDEATR
QVFQDLA-------------------EEEFGYKTLVKRLGGVGRQELSTQIVLRLMEAGL
LTG---------YDSDGAKVTVQGRLHFGGVGVEYEV-----------------------
----------------
>NC_013093.1|c4|3689718-3691043|-|YP_003100941.1|tryptophan_halogenase
------------------------------------------------------------
-------------------------M---LDAIVMGGGPAGAVCASVLARQ--GRSVLVL
ERQEFP----R--FHIGESMLPY----------------MVGLLERHGLLDAVREQ--GY
VVKRGGEF--IDPTGTKFFRAG-----------VFRADFAKTGDGRHHETF---------
-------QVERSHFDRVNLDQ-ARAAGATVREGAQVVGLLEE--------------GG--
-RVVGVRYREGG----VEREE----RARYVVDATGRAGVVANRFG----LRRMIEDLR--
M-VAVFHHRDGLDEAH----------------NPGHEG--DIQVGS-----HADG---WI
WAIPL-------SAD-RISVGTVMHRDRL-RG-----RTPAEA--FAEHVERV-PR----
----INQ-RLTGTTATSD-----FWVETDY-SYHSDQVTG--PGWVMVGDAGCFGDPMFS
GGVLVGMATGAEAAEALGRAL--DSPADEEQA---LTGYSNFF--KTGYDT-YVRLIFS-
-FYEG-----ELL-----PALAEAHSEAGDLS-----------------EADME-----M
YVVRL----------LGG------------------------------------------
-------------------------DFWSARN-------PVANALRANPA----------
--------------------------WSTFSPFEPVHRCPVYPELDVAELGGLAGAVGR-
------------------------------------------------------------
----------------
>GG698948.1|c2|156367-158084|+|EEU34964.1|hypothetical_protein
------------------------------------------------------------
--------------------MSVPSQ---TSVLIVGAGPAGSYAACVLARE--GVDVVLV
DADKFP----R--YHIGESMLAA----------------IRFLLRLIDAEEAFDKH--GF
EKKFGATF--KITDK------------------REAFTDFSEALGPGGHSW---------
-------NVIRSEADELLFKH-AANNGAKTFDGTKVDSINFEPLPDFEMGEGSHLANPG-
-RPVSADWSRKD---GTRGNI----KFDYLIDASGRNGIICTKYL---KNRKFNEGLK--
N-LAQWTYWKGAKRFNVSKRNEN---------SPFFEN------LD-----DASG---WV
WAIPL-------HNG-TLSVGIVARQDLFLAKKKELGLSGQEF--YREYLKLA-PQ----
----ISE-MLSNAEIVAD-----VKQASDW-SYSASAYAG--PYFRVAGDAAAFVDPYFS
SGVHLALNNGLAAAVSIQASR--RGQADERAA---AKWHATKV--AENYTRLLLIVMAV-
-QRQLRLKHEELITSNSEDGFDTAF----------------------------------K
AIQPV----------IQGVADTHESDAS-----------------------VQNKAVESV
NFALE--------------------SFEVTPE-------QEKLMTEKVVQAAQRAPETLQ
KMTPE---------------------EVDILKRMSHRVLHRNTNRNNKGLVDFTGQVIDG
FSA---------ILERGDVGLIKVED----------------------------------
----------------
>EU520419.1|c1|8912-10848|+|ACD39771.1|non-heme_halogenase
------------------------------------------------------------
--------------------MSVPKS---CTILVAGGGPAGSYAAAALARE--GNDVVLL
EADQHP----R--YHIGESMLPS----------------LRPLLRFIDLEDKFDAH--GF
QKKLGAAF--------------------------KLTSKREGSHGPRGYSW---------
-------NVVRSESDEILFNH-ARESGAQAFQGIKINAIEFEPYEEEYPNGEKVANPG--
-KPTSAKWSSKD---GSSGDI----AFKYLVDATGRIGIMSTKYL---KNRHYNEGLK--
N-LAIWGYYKNN--------------------IPWAQGTPRENQPFFEGMRDGAG---WC
WTIPL-------HNG-TVSVGAVMRKDLFFEKKKSLGENATNTQIMAECMKLC-PT----
----IGE-LLAPAELVSD-----IKQATDY-SYSATAYAG--PNFRIVGDAGCFIDPFFS
SGHHLAVAGALAAAVSINASI--KGDCTEYEA---SRWHAKKV--DEGYTLFLLVVMAA-
-LKQIRMQENPVLSDVDEDGFDRAFQFLRPEAVKKF-------------TKEDV-----A
QTIDFAVHA------LNNMAELDMDIPE--------------------------------
-------------------------HMINGDK-------EGENGVTNGNNGAAKTAGLAS
NMEKLTN-------------------DEEKVLNGLRILGKAAPGGTLADFEG--------
------------TAIDGLMPRLEHGKLGLNKV----------------------------
----------------
>EU980390.1|c1|7828-9693|-|ACM42402.1|RadH_flavin-dependent_halogenase
------------------------------------------------------------
--------------------MSIPKS---CEVLVAGGGPAGSYAASALARE--GVDVVLL
EADKHP----R--YHIGESMLPS----------------IRPLLRFIDLEETFEKH--GF
QKKLGAAF--KLTAK------------------REGYTDFVAAHGPNGYSW---------
-------NVVRSESDELLFKH-AAKSGALTFQGVKVDSLEFEPYDSDFPSGGKVANPG--
-RPVAARWSAKD---GRSGTI----SFQYLVDATGRAGITSTKYL---KNRKFNEGLK--
N-LAIWGYYKGA--------------------RPWAEGTPRENQPYFEGMRDGAG---WC
WTIPL-------HNG-TVSVGAVLRSDLFFAKKKSLGEDVTNAMIMAECMKLC-PT----
----IKE-LLEPAELVSD-----IKQATDY-SYSASAYAG--PYFRIVGDAGCFIDPFFS
SGHHLAMAGALAAAVSIRASM--KGDCSEYEA---SNWHARKV--DEGYTLFLLVVMAA-
-LKQIRMQEEPVLSDIDDDGFDRAFQFLKPVIQGSG-------------SAEIV-----K
RFTKKEV--------SEAIDFAVLALDN--------------------------------
-------------------------MAGAGEHANETNGSNGTGETNGDAKTLENITVEDE
KVLSGI--------------------RILAKVAPSADMKDLEGTAIDGFMPRLEHGHLGL
NRV---------------------------------------------------------
----------------
>NC_013131.1|c5|3119401-3120921|+|YP_003113480.1|tryptophan_halogenase
------------------------------------------------------------
--------MSRSDRRILTKRMVFSEM---TEVIVVGGGPAGSTAAALLAKN--GVSVTLL
EREAFP----R--YHVGESITYS----------------CRGVLDYIGALEKIEAR--GY
TRKTGVLL--RWGQE------------------LDWAIDWTAQFGPDVRSW---------
-------QVDREDFDQVLLQH-AAECGAQVLEQAQVKRVVFE--------------DG--
-RAVGVEWTPQG--HSEPQIT----RADLVLDASGRAGLISAQHF---RDRRATEIFR--
N-VAIWGYWDGGEL------------------LPDSPSGSINVISS-----P-EG---WY
WVIPL-------SGN-RFSVGYVTHKSVF-VERRKDYDTLDDM--LAAVVAES-PT----
----VSE-AMAKGTVRPG-----ARVEQDF-SYAADSFCG--PGHFLVGDAACFLDPLLS
TGVHLAIYSGLLAAASVLSIE--NGDVTETEA---YAFYESRY--RNSYER-LFTLVAG-
-FYQKHAGKDRYF-----ELAKALTREHKGL------------------EGSAD-----L
AFGEI----------TSGITDLREAKD---------------------------------
-------------------------DSGLGDR-------PIRESVAEAASRRSKVQDLLS
A-------------------------TEQAQQRAEAGLPNTGGDRGRSRVQIDADDLY--
------------DAATGLHLVMEPRLGIQRAAVPAAG-----------------------
----------------
>NZ_GG657738.1|c12|4379493-4380971|-|ZP_04607391.1|halogenase
------------------------------------------------------------
------------------------MS---SKILVIGGGPAGSTAAALLARS--GLSVTLL
EKETFP----R--YHIGESIASS----------------CRTIVDFVGALDEVDSR--GY
PQKNGVLL--RWGN-------------------EDWAIDWAKIFGPGVRSW---------
-------QVDRDDFDHVLLNN-AGKQGAKIIQGAAVKRVLFD--------------GE--
-RATAAEWFDPE--SGEVRTI----DFDYVVDASGRAGLIPSQHF---KHRRPTETFK--
N-VAIWGYWQGGSL------------------LPNSPSGGINVISA-----P-DG---WY
WVIPL-------RGD-RYSIGFVCHQSRF-LERRKEHASLEDM--LAALVQES-PT----
----VRG-LTANGTYQPG-----VRVEQDF-SYISDSFCG--PGYFAAGDSACFLDPLLS
TGVHLALYSGMLASASILATI--HGDVTEEEA---RAFYESLY--RNAYQR-LFTLVAG-
-VYQQQAGKRAYF-----GLADALVHDSG--------------------EPEYEKVDGAR
AFAQL----------VAGLADLDDAAEGRHDS----------------------------
-------------------------TAAAAPA-------EQDNSVRQLFLAAEEARRMAD
ARTPSAPV------------------SEAPGKLDSHDLFDSATGLYLVTTPRLGIRR---
------------AKPADTQAAAEQSA----------------------------------
----------------
>AM179409.1|c1|38459-40027|+|CAJ46693.1|tryptophan_halogenase
------------------------------------------------------------
--------------------MQLPSS---TKILVVGGGPAGSTAATLLARE--GFEVTLV
EKAIFP----R--YHIGESLLIS----------------VQPIIDLLGAREAVEAH--GF
QRKKGVLW--EWGG-------------------ERWLFDWKKLR--YDYTF---------
-------HVKREEFDEILLRN-AQKNGVKVFEGIDISRLEFD--------------GE--
-RPVAAKWSKSS--TGESGTI----QFEFLLDASGRAGLMATQYL---RSRMFMKAFQ--
N-VATWGYWKGATIPE----------------VEVEGPITVGSIPY-----G------WI
WGIPL-------RDQ-TMSVGLVIHQELF-KEKRAT-QSVEEI--YHEGLKAS-PL----
----FQDVVLKGATLEPQ-----IRTETDY-SYISRTLAG--PGFFLVGDSGAFIDPLLS
SGVHLAMHSALLAAASVKSII--AGEVDMASA---TEFYQRCY--QGHFLR-WALIVAS-
-FYEV------NA-----RKETYFWTAQQLAHEELGVFNMS--------QADMK-----D
VFATM----------VSGVVDLGDAQNA-----------------------GRLQKGAER
VH-----------------------QYLDDDG-------REEDVTALLQKSKQRIFEYLD
RVKNRDS-------------------RAAMQRYKAGGTETFSMGLDADGAVGGLYVTTEP
RLGLLRKVVEERAEAATEAPAPAAPPPAVAEV----------------------------
----------------
>EF159954.1|c1|48796-50271|+|ABM21576.1|CrpH
------------------------------------------------------------
-------------------MSTLPNS---TQILIIGGGPSGSTAATLLARE--GFDVTLL
EREVFP----R--YHVGESLLPSA----------------LEIFDLLGVREKIEAY--GF
QRKPGAYI--EWGT-------------------EKWSLNFGELTGDNTYSF---------
-------QVRRDEFDHLLLEH-SKSQGVKVFEGTKIRQLSFD--------------GD--
-RPRSATWSQSN---DTTGEI----SFDFMIDASGRAGIMATEYL---KNRRLHDVFQ--
N-VGIWGYWKNALR------------------LPKGQSGAIALGSI-----P-DG---WV
WGIPL-------DEE-IMSVGVVMHKSTY-KERLT--KNLKDI--YVEAIAEC-PL----
----IAD-LVALGELVSD-----VKVEQDY-SYTSDSFSG--PAYFISGDAACFLDPLLS
SGVHLATYSALLAAASITSVI--RGEVTESQA---ASFYDQSY--RQAYLR-FLVFVSA-
-FYDQNRGKDSYF-----WEAQRLSRRDFG-------------------SSNLK-----L
AFLNL----------VSGVEDLEDAKEG-----------------------IADFVMAEM
SQRIQSSH-----------------SIRQDKQ-------ALAIEREKGNEVMKTNAQFFN
AVEGFSI-------------------LSAVGAVDGLYVTTQPKLGLVQVIPLQRNSLLHT
------------------------------------------------------------
----------------
>NC_013595.1|c14|4630503-4631915|+|YP_003339808.1|putative_tryptophan_halogenase
------------------------------------------------------------
----------------------MRES---TQILIIGGGPAGSTAAGLLARE--GFQVTLL
ERDRFP----R--YHIGESILPS----------------CRPIFELLGVWDKVEAH--GF
QPKGGAFF--QWGP-------------------EEWEVRFSNLGDDTPNAW---------
-------QVIRSEFDQLLLDH-ARELGVEVIEGVSVRDIEFD--------------GD--
-RAVAARWYDTK-DPERSGRI----EFGHVIDASGRGGVLATRHL---KNRRFHDVFR--
N-VAAWTYWKNAKP------------------LSKGPSGAIAVCSV-----E-DG---WF
WAIPL-------HDG-TLSVGLVTGRDLFNDSRGRLNGDIQAV--YDEALAKC-PT----
----VLE-LLDGAEQVSG-----MKVEQDY-SYVAENFAG--PGYLLSGDAACFLDPLLS
TGVHLATYSAMLGAASLSSVL--RGEVAEQDA---WRFYNTVY--HHAYQR-LLILVSV-
-FYESYRGKEHHF-----YNAQRLTSDERD-------------------HLNLQ-----A
AFDRI----------ITGIADLNDAEQ---------------------------------
-------------------------AYRLVQE-------HLRGGESGDPNPLNNLNRVHE
V------------------------------KQSPFDPANAVGGLYLVTEPRLGLRSNGA
TPSDPS------------------------------------------------------
----------------
>AM988861.1|c1|5294-6832|-|CAQ43074.1|halogenase
------------------------------------------------------------
-------------------MSTRPEV---FDLIVIGGGPGGSTLASFVAMR--GHRVLLL
EREAFP----R--HQIGESLLPAT---------------VHGICAMLGLTDEMKRA--GF
PIKRGGTF--RWGKEPE----------------PWTFGFTRHPDDPYGFAY---------
-------QVERARFDDMLLRN-SERKGVDVRERHEVIDVLFE--------------GE--
-RAVGVRYRNTE---GVELMA----HARFIVDASGNRTRVSQAVG----ERVYSRFFQ--
N-VALYGYFEN--------GKRLP--------APRQGN--ILSAAF-----Q-DG---WF
WYIPL-------SDT-LTSVGAVVSREAA-EAIK---DGHEAA--LLRYIDRC-PI----
----IKE-YLAPATRVTTGDYGEIRIRKDY-SYCNTSFWK--NGMALVGDAACFVDPVFS
SGVHLATYSALLVARAINTCL--AGEMSEQRC---FEEFERRY--RREYGN-FYQFLVA-
-FYDM------NQ-----DTDSYFWSARKIINT----------------EERAN-----E
AFVRL----------IAGRSNLDEPVFQ-----------------------SVAKDFFTE
REGFGAWFGGLVTSMAK--------GDGGGLM-------VGEGATDATESTGFAPENFMQ
GFTREI---------------------------TELQHLAMFGEDRGPETPLWSGGLV--
------------PSRDGLAWAVESGEDAAG------------------------------
----------------
>AY271660.2|c1|46957-48513|-|ABY66006.1|halogenase
------------------------------------------------------------
-------------MSERTETYDRTEE---YDVVVVGGGPCGSTVSTLVARQ--GHRVLVL
EKESFP----R--YQIGESLLPAT---------------VHGICKLLGVTEELERA--AF
TVKRGGTF--RWGANPEPW--------------TFAFAVSSHFAGDAATAY---------
-------QVERMTFDKILLDN-ARRNGVEVRERVSVVDVVEE--------------DD--
-RVAGVRYVDTD---GTRREV----RARFVVDASGNKSRIHDRVG---GRRHYSEFFR--
N-LALFGYFEGGKRMP----------------APNEGN--ILAVAF-----D-AG---WF
WYIPL-------GPD-LTSVGAVVQPEAL-DRIR---GDREEA--LRSLIADC-PM----
----IAD-YLSGARRVTEGPYGEIRTRKDY-SYIKEAFWK--PGMVLAGDAACFIDPVFS
SGVHLATYSALLAARSINTVL--RGDATEADC---FAEFEDRY--RREYAR-FHDFLVA-
-FYDMHH-----------DENSYFWKAKKVTRN----------------AASDL-----E
AFVEL----------VGGGSSQENALVA--------------------------ADAYAS
DAPPSEE------------------SYSAGRHA------AFRELSDIVERPVDAAGEDRD
LLGSALA-------------------RSVSREGTRIQVQAALGGNADEHVPVRPGGLV--
------------PSADGMHWSVPAAPAGTAD-----------------------------
----------------
>DQ403252.1|c1|41890-43404|-|ABD65950.1|halogenase
------------------------------------------------------------
-------------MPGGRMSTGQHEE---FDVVVVGGGPSGSTLSTLVAMQ--GHSVLLL
EKETFP----R--YQIGESLLPST---------------IHGICHLLGVTDELAAA--GF
PHKRGGTF--RWGASPKPW--------------NFSFSVSSKVSGPTSFAY---------
-------QVERSKFDKILLDN-AARKGVVVRQDRTVTDVVDD--------------ADG-
-RARGLRYTDPD---GTEHEV----SARYVVDASGNTSRIHKRVG---GSRTYSDFFK--
S-LALFGYFEN--------GKRMP--------APYAGN--ILCVAF-----G-SG---WF
WYIPL-------SST-LTSVGAVVRREDA-AKVQ---GDPESA--LRGLIDEC-PM----
----IKE-YLADATRVTTGQYGQLRVRKDY-SYHHTTFWR--PGMVLVGDAACFVDPVFS
SGVHLATYSALLAARSLNSVL--AGRIDERRA---FDEFEARY--RREYGV-FYEFLTS-
-FYDM------HV-----DEDSYFWTAKKVTRS----------------SHAEL-----E
SFVEL----------VAGMSSTDFDLSD-----------------------AESS-----
-------------------------VLRLKQQ-------SAEFADAVDDMAGRQEENMAP
LFRSSAV-------------------SRAMQEGSQVQTRAQLGEYAGEDVPLFDGGLV--
------------ASSDSMFWEEPHPS----------------------------------
----------------
>AF386507.1|c1|39504-40997|+|AAK81830.1|non-heme_halogenase
------------------------------------------------------------
-------------------MAAVTEE---FDVAVVGGGPAGSTFAALVAKQ--GHRVVVL
EKENFP----R--YQIGESLLPST---------------IHGVCRLSGAADDLAKA--GF
PLKRGGTF--RWGARPEPW--------------TFAFSVSPRMAGPTSVAY---------
-------QVERSKFDDILLKN-ARKQGADVREGCSVRGVIEE--------------GE--
-RVRGLTYADAD---GNEREI----RARYVVDASGNKSRLYNKVG---GTREYSDFFR--
S-LALFGYFENGKR------------------MPEPNRFNILCVAF-----E-SG---WF
WYIPL-------SDT-LTSVGAVVRREMA-EKIQ---GDPEKA--LRALIDEC-PM----
----IAD-YLSDATRVTEGQYGEIRVRKDY-SYHHTTFTR--PGMMLVGDAACFVDPVFS
SGVHLATYSSLLAARSLNSVL--EGKVDEDAA---MKEFEARY--RREYGV-FYEFLVS-
-FYEMHR-----------DENSYFWQAKKVTANS---------------EPEL------Q
SFVEL----------IGGVSSGEQGLMN--------------------------------
---------------------TDALSERLADN-------SEEFATAVEKFAANEDGSSVP
LFSSSVV-------------------RNAMQEAGQVQMRALLGEDAEPETPMFPGGLV--
------------SSPDGLYWLPATTA----------------------------------
----------------
>NC_007777.1|c14|2905915-2907402|-|YP_481561.1|tryptophan_halogenase
------------------------------------------------------------
--------------------MTDSAE---FDVVVVGGGPAGSTLAALVAMQ--GHRVLVL
EKEHFP----R--YQIGESLLPST---------------IHGVCRLTGAADELAKA--GF
PLKRGGTF--RWGATPEPW--------------TFAFSVSSRMAGPTSFAY---------
-------QVERSKFDEILLRN-ARRVGAEVHEGCSATDVIED--------------GD--
-RVVGIRYTDDG---GNRREA----RASFVVDATGNKSRIYHRVG---GTRQYSEFFR--
S-LALFGYFEGGRR------------------MPEPNRNNILCVAF-----D-SG---WF
WYIPL-------SDT-LTSVGAVVRSEMA-EKVQ---GDSEQA--MKALIEEC-PM----
----ISD-YLAPARRVTTGQYGQLRVRKDY-SYHQTTFWR--PGMVLVGDAACFVDPVFS
SGVHLATYSALLAARSINSVL--AEIVDEKTA---MQEFEARY--RRDYGV-FYEFLVS-
-FYEMHH-----------SEDSYFWQAKKVTGNS---------------QPEL------E
AFVEL----------IGGVSSGESALTD--------------------------------
---------------------ADALALRLQAN-------TADFTTAVDALVANNSESMVP
FMKSQVI-------------------RGVMHEGSQMQMRALLGEDAEPETPLFPGGLV--
------------SSADGMFWLPTDA-----------------------------------
----------------
>U82965.2|c1|4960-6267|-|AAM80530.1|StaK
------------------------------------------------------------
---------------------MSAET---FDVVVAGGGPAGSTAASLVAMQ--GHRVLLV
EKEVLP----R--HRVGESLLPST---------------VHGVCRMLGVTDELAET--DF
PVKRGATF--QWGGRAEPW--------------AFSFGASSRLTDATSFAY---------
-------QADRARFDEILLKN-AKRKGVVVREGCSVTAVVEE--------------GD--
-RVTGLRHTDPD---GGEHEV----GARFVIDASGHESPLSASVG---GTRDRAGSFR--
G-LALSGYFGN-----GCKRLP----------EPRSGD--GLSVTF-----D-GG---WF
WYVPL-------FGG-LTSVGAVVSEERA-EKLQ---DDREEA--FKALIAEC-PA----
----ISD-LLSEGMRVTAGKYGKLRVREDY-VYHRTTFWR--PGMLLVGDAACSVDPLFS
SGVHLATYSALLAARSINSVL--AGDVDEKTA---LTEFEARY--RRELGA-FSELLTT-
-FHTMTGEEHPEP----------------------------------------------E
SFVDV----------AAGVSSGEWALAA--------------------------------
-------------------------QGGGAAA-------PGEPMFRGGLA----------
------------------------------------------------------------
------------VSPDGMKWLPAASKEREDAR----------------------------
----------------
>EU874252.1|c1|38009-39484|+|ACJ60955.1|Veg13
------------------------------------------------------------
---------------------MSVED---FDVVVAGGGPSGSTVATLVAMQ--GHRVLLV
EKEVFP----R--YQIGESLLPAT---------------VHGVCRMLGVTDELAGA--GF
PIKRGGTF--RWGARPEPW--------------TFHFGISARMSGATSHAY---------
-------QVERARFDEILLNN-AKSKGVVVREGCSATDVVED--------------GE--
-RVTGLKYTDAD---GNGREV----SARFVIDASGNLSRLYSKVG---GKRNYSEFFR--
S-LALFGYFEG-----G-KRLP----------APVSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-LTSVGAVVRREDA-DKIQ---GDREKA--LNALIAEC-PL----
----ISE-YLENATRVTTGKYGELRIRKDY-SYQQESYWR--PGMVLVGDAACFVDPVFS
SGVHLATYSALLAARSINSIL--AGDLDEKTA---FNEFEARY--RREYGV-FYEFLVS-
-FYQM------NV-----NEESYFWQAKKVTQN----------------QSTDI-----E
SFVEL----------IGGVSSGETALTA--------------------------------
-------------------------ADRIAAR-------SAEFAAAVDEMASGDGDNMVP
MFKSTVV-------------------KQAMQEAGQVQMKALLGEDAEPEMPLFPGGLV--
------------TSPDGMKWLPYHPA----------------------------------
----------------
>AJ223998.1|c1|1076-2551|+|CAA11780.1|PCZA361.26
------------------------------------------------------------
---------------------MSVED---FDVVVAGGGPAGSTVATLVAMQ--GHRVLLL
EKEVFP----R--YQIGESLLPAT---------------VHGVCRMLGITDELANA--GF
PVKRGGTF--RWGARPEPW--------------TFHFGISAKMAGSTSHAY---------
-------QVERARFDEILLNN-AKRKGVVVREGSPVTDVVED--------------GE--
-RVTGLRYTDAD---GNEREV----SARFVIDASGNKSRLYSKVG---GSRNYSEFFR--
S-LALFGYFEG-----G-KRLP----------APVSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-LTSVGAVVRREDA-EKIQ---GDREKA--LNALIAEC-PL----
----ISE-YLANATRVTTGKYGELRVRKDY-SYQQETYWR--PGMILIGDAACFVDPVFS
SGVHLATYSALLAARSINSVL--AGDLDEKTA---LNEFEMRY--RREYGV-FYEFLVS-
-FYQM------NV-----NEESYFWQAKKVTQN----------------QSTDI-----E
SFVEL----------IGGVSSGETALTA--------------------------------
-------------------------ADRIAAR-------SAEFAAAVDQMASGDGDNMVP
MFKSTVV-------------------KQAMQEAGQVQMKALLGEDAEPELPLFPGGLV--
------------TSPDGMKWLPHHPA----------------------------------
----------------
>Y16952.3|c1|38634-40109|+|CAA76550.1|halogenase
------------------------------------------------------------
---------------------MSVED---FDVVVAGGGPGGSTVATLVAMQ--GHRVLLL
EKEVFP----R--YQIGESLLPAT---------------VHGVCRMLGISDELANA--GF
PIKRGGTF--RWGARPEPW--------------TFHFGISAKMAGSTSHAY---------
-------QVERARFDEMLLNN-AKRKGVVVREGCAVTDVVED--------------GE--
-RVTGARYTDPD---GTEREV----SARFVIDASGNKSRLYTKVG---GSRNYSEFFR--
S-LALFGYFEGGKRLP----------------EPVSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-LTSVGAVVRREDA-EKIQ---GDREKA--LNTLIAEC-PL----
----ISE-YLADATRVTTGRYGELRVRKDY-SYQQETYWR--PGMILVGDAACFVDPVFS
SGVHLATYSALLAARSINSVL--AGDLDEKTA---LNEFELRY--RREYGV-FYEFLVS-
-FYQMNV-----------NEESYFWQAKKVTQN----------------QSTDV-----E
SFVEL----------IGGVSSGETALTA--------------------------------
-------------------------ADRIAAR-------SAEFAAAVDEMAGGDGDNMVP
MFKSTVV-------------------QQAMQEAGQVQMKALLGEDAEPELPLFPGGLV--
------------TSPERMKWLPHHPA----------------------------------
----------------
>AJ605139.1|c1|57509-59029|+|CAE53362.1|halogenase
------------------------------------------------------------
------MTSLSSDDSIDGWWKMPVEE---FDVVVAGGGPAGSTVATLVAMQ--GHRVLLL
EKETFP----R--YQIGESLLPST---------------VHGVCRMLGVSDELAAA--GF
PVKRGGTF--RWGARPEPW--------------TFSFAVSPLMNGPTSFAY---------
-------QVERARFDEILLRN-AQRKGVDVREGCSVTGVIEG--------------DE--
-RITGVRYTDPD---GGEHEV----SARFVVDASGNKSRLYSQVG---GVRNYSEFFR--
S-LALFGYFENGKRLP----------------EPYSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-MTSVGAVVRREMA-EKIQ---GDREKA--LQALIAEC-PL----
----ISD-YLADARRITTGRYGELRVRKDY-SYHQTSYWR--PGMILVGDAACFVDPVFS
SGVHLATYSALLAARSINSVL--AEDLDEKTA---LSEFEARY--RREYGV-FYEFLVS-
-FYQMNV-----------NEESYFWQAKKVTNN----------------KHTEI-----E
SFVEL----------IGGVSSGEAALAT--------------------------------
-------------------------AGRIAER-------SAEFAAAVDQMAASADGNMVP
MYKSEVV-------------------KQVMQEGGQVQMKAVLGADAEPELPLFPGGLV--
------------VSPDGMKWLPYRPA----------------------------------
----------------
>AJ632270.1|c1|50931-52406|+|CAG15020.1|halogenase
------------------------------------------------------------
---------------------MPVEE---FDVVVAGGGPAGSTVATLVAMQ--GHRVLLL
EKETFP----R--YQIGESLLPST---------------VHGVCRMLGVSDELAAA--GF
PVKRGGTF--RWGARPEPW--------------TFSFAVSPLMNGPTSFAY---------
-------QVERARFDEILLRN-AQRKGVDVREGCSVTGVIEG--------------DE--
-RITGVRYTDPD---GGEHEV----SARFVVDASGNKSRLYSQVG---GVRNYSEFFR--
S-LALFGYFENGKRLP----------------EPYSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-MTSVGAVVRREMA-EKIQ---GDREKA--LQALIAEC-PL----
----ISD-YLADARRITTGRYGELRVRKDY-SYHQTSYWR--PGMILVGDAACFVDPVFS
SGVHLATYSALLAARSINSVL--AEDLDEKTA---LSEFEARY--RREYGV-FYEFLVS-
-FYQMNV-----------NEESYFWQAKKVTNN----------------KHTEI-----E
SFVEL----------IGGVSSGEAALAT--------------------------------
-------------------------AGRIAER-------SAEFAAAVDQMAASADGNMVP
MYKSEVV-------------------KQVMQEGGQVQMKAVLGADAEPELPLFPGGLV--
------------VSPDGMKWLPYRPA----------------------------------
----------------
>AJ561198.1|c1|18152-19621|-|CAD91205.1|halogenase
------------------------------------------------------------
-----------------------MEE---FDVVVAGGGPGGSTVATLVAMQ--GHRVLLV
EKEVFP----R--YQIGESLLPST---------------VHGVCRMLGVTDELAAA--GF
PVKRGGTF--RWGARPEPW--------------TFSFSVSPRITGPTTFAY---------
-------QVERARFDEILLGN-ARRKGVVVREGCSVTEVIED--------------GD--
-RVTGLRYVDPD---GGEHAV----SARFVIDASGNKSRLYSSVG---GTRNYSEFFR--
S-LALFGYFEG-----G-KRLA----------EPYSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-LTSVGAVVRREMA-EKIQ---GDREKA--LAALIAEC-PL----
----ISE-YLAPARRVTTGKYGQLRVRKDY-SYHQTKFWR--PGMILVGDAACFVDPVFS
SGVHLATYSGLLAARSINSVL--AGDVEEKIA---LHEFEARY--RREYSV-YYEFLLA-
-FYEM------NV-----NEESYFWHAKKVTNNK---------------EYTEL-----E
SFVDL----------VGGLSSGETALAT--------------------------------
-------------------------SGRIAER-------SAEFAAAVDQMADGDDSSMVP
LFKSQVV-------------------KQVMQEGGQEQMRAVLGADAEPEQPLFPGGLV--
------------TSPDGMRWLTHHP-----------------------------------
----------------
>U82965.2|c1|7534-9072|-|AAM80532.1|StaI
----------------------------------------------------------MD
GLSGDPLPSTIAKDSIEGWWEMSVET---FDVVVAGGGPGGSTVAALVAMQ--GHRVLLL
EKEVFP----R--YQIGESLLPST---------------VHGVCRLLGVTDELAAA--KF
PVKRGGTF--RWGARPEPW--------------TFSFAVSPRMTGPTSFAY---------
-------QVERARFDEILLNN-AKSKGVTVREGCSVTAVVEE--------------GD--
-RVTGLRYTDSD---GGEHEV----GARFVIDASGNKSRLHASVG---GTREYSEFFR--
S-LALFGYFENGKRLP----------------EPYSGN--ILSVAF-----D-SG---WF
WYIPL-------SDT-LTSVGVVVRREMA-EKIQ---GDREKA--YNALIAEC-PL----
----IAE-YLSDARRVTTGNYGELRVRKDY-SYHQTKFWR--PGMILVGDAACFVDPVFS
SGVHLATYSALLAARSINSVL--AGDLDEKTA---FDEFEGRY--RREYGV-FYEFLVS-
-FYQMNV-----------NEESYFWHAKKVTNN----------------EHTEF-----E
SFVDL----------VGGVASGETALA---------------------------------
-------------------------ASRLAER-------SAEFAGAVDQMAGGDDGDMVP
LFKSHVV-------------------KQVMQEGGQVQMKAVLGEDAAPEEPVFPGGLV--
------------SSPDGMKWLPYRG-----------------------------------
----------------
>EU874253.1|c1|41226-42707|+|ACJ60999.1|Teg16
------------------------------------------------------------
---------------------MSVEE---FDVVVAGGGPAGSTVASLVAMQ--GYRVLLL
EKEVFP----R--YQIGESLLPST---------------VHGVCRLLGVTDELAKA--KF
PVKRGGTF--RWGARPEPW--------------TFSFAVSSRMTGPTSFAY---------
-------QVERARFDEILLNN-AKRKGVVVREGCAVAGVIEE--------------GE--
-RVTGLRYTDPD---GGEREV----SASFVIDASGNKSRLYSSVG---GTRNYSEFFR--
S-LALFGYFGG-----GTKRLP----------EPNSGN--ILSVAF-----D-SG---WF
WYIPL-------RDSGLTSVGAVVRREMA-EKIQ---GDREKA--FNALIAEC-PL----
----ISE-YLSGAQRVTAGKYGELRVRKDY-SYHQTTFWR--PGMVLVGDAACFVDPVFS
SGVHLATYSGLLAARSINSVL--AGDLDEKTA---LTEFEARY--RREYGV-FYEFLMS-
-FYEM------NV-----NEESYFWHAKKVTNN----------------EHTEL-----E
SFVEL----------VGGVSSGEAALTA--------------------------------
-------------------------AARIAER-------SGEFAAAVDQVADSDDGSMVP
LFKSQVV-------------------KQVMQEGGQVQMKAVLGEDAEPEVPLFPGGLV--
------------ASPDGMKWLPYYPA----------------------------------
----------------
>EF397638.1|c1|21698-23038|+|ABS50460.1|NapH2
------------------------------------------------------MRGGGL
HANRWCGRIGTGRSYMSSNVVGFSGD---FDVIVIGGGPAGATTAALLSKR--GRRVLVL
DRERFP----R--YHVGESLIPG----------------VMVPMEELGLKERMEAK--GF
ERKYGGTL--VWGNN------------------EVPWNFSFSTGGRIPYAF---------
-------HTRRADLDALVLDR-ARELGAFVVEDATVKDTIEE--------------DG--
-RVVGVRYALRG--LGGTQEA----RASLVIDASGQARVIGRKYT----EVNWNEQLR--
N-VAVWTYFDN-----CHRLPG----------DEWSN---ILIEGT-----S-DG---WF
WGIPI-------DKG-VFSVGYVTRSELA-TESG---KSLEDL--FQSEIAST-TK----
----LKE-LLKDATQAAG-----YRSARDW-SYTNDRFYG--KGWALVGDAAAFVDPLFS
TGVALATLAGSTLSKVVDQIL--QYPAIEEKA---LDRYSNAY--QEFFHD-IRKFVEG-
-FYDRSKTKGFYF-----NMAQEMVDPEK--------------------ENAAE-----V
DFVKL----------VSGLSGR--------------------------------------
-------------------------QGGLFEL-------NVDDLIEDAKSTPTGS-----
------------------------------------------------------------
------------------------------------------------------------
----------------
>NC_009953.1|c7|2324552-2325793|-|YP_001536892.1|tryptophan_halogenase
------------------------------------------------------------
-------------------MRQPVAE---YDVIVVGGGPAGACTAGLLALE--GHRILLL
EREKFP----R--YHVGESLITG----------------VVPTLTALGLLDRMAEL--RF
QVKYGGSL--LWGENQTE---------------PWSFRFREIRGGRYEYAW---------
-------QVRRAEFDAMLLDR-ARELGVHVVEGATVRDALTD--------------GD--
-RLAGVRYQLKG--ESGSVPA----RATMVVDASGQHRWLGRRFG----LVDWYDDLR--
N-VAVWSYWQGALRYP----------------GEHEGD--LLTESC-----R-QG---WL
WYAPL-------SPE-LTGIGYVTTSDRL-VASG---LTPEQL--LERHIAES-SE----
----VSW-LTAGAKRVDI-----YRAARDW-SYTCQQFSG--PGWVLVGDAAAFIDPLLS
AGVTLAMRAASSVAKAVHETL--TAPDKERHV---MKDYEDRY--RDFLGS-LLELVRF-
-FYDGAHGKEELH-----LRAQAIVDPDRSL------------------PPKLS------
-FVSL----------LSGLVRGDESLG---------------------------------
-------------------------ADAVDEY----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
