>NC_007520.2|c2|1868822-1869724|+|YP_391974.1|pseudouridine_synthase
-----------------------------------MTTTQNIARFELHFTLQQSEKTLLE
ALSEHLPNEVHFSNQQLKRFCQQGAVWISEPGNQPDQQTKKVRARRAKKQLKKGSEVSFY
FNESVLNATIPD------------PVLIEDADDFSVWYKPKGVLSQGSKW-GDHTTLNRW
---IETHYLFKEPPEKRP-CWI-------VHRLDKATDGLILIAHNKKSAQMLARRFEA-
-----HQIGKSYQAWVKGKF-----------------------------GE-TER-VF--
---DQDV-NG---KTALSKAHQLV---------YNSDNDCSLVQVTIATGRKHQIRIHLS
KAGFPIIGDRLYGD------AQE--------G-------DPDLQ-----LTAVEITFLSP
-QGTIEQRFQ---------LPDNLRPSVSI------------------------------
---------------------
>NZ_GG770381.1|c1|74784-75674|+|ZP_06747435.1|tRNA_pseudouridine_synthase_A
---------------------------MMEFIIDEEYETVRIDRFLRKHLK-NIALSEIY
KMLRKAKIKVNNKKV-SQDYRLILGDIIFVFLPENFKEKNEDET----------------
-FIELNEIRKEK----------LKSMITYENENLFIINKNLGDVIHKGSG----------
---HDISLLEEFRAYYSN-NKVN---F--VNRIDKLTSGLVIGAKNIKTAREIAKEIQL-
-----GNITKKYYILVYGKIEKEEFILENYLKKDE--------------EKVIVS-----
---DIEK-ED--YKKSITHYKRIN-----------GNDDYTLLEAELKTGRTHQLRAQLN
HIGHTIVGDTKYGK------NIK----------------EETMY-----LFSYYLKIDLY
-----DLELE-------MGIPDFFFKKYNIQ--K--------------------------
---------------------
>NZ_GG657936.1|c2|885229-886116|-|ZP_04571219.1|tRNA_pseudouridine_synthase_A
---------------------------MIEFIIDEEYETVRIDRFLRKHLK-NIALSEIY
KMLRKAKIKVNNKKVSQDYRLVLGDIIFVFLPESFEEKNEETFI----------------
-ELNEIRKEELK------------SMIAYENENLFIINKNLGDVIHKGSG-------HD-
---ISLLEEFRSYYSNNK-INF-------VNRIDKLTSGLVIGAKNIKTAREIAKEIQL-
-----GNILKKYYILVYGKIEKEEFILENYLKKDE--------------EKVIVS-----
---DVEK-ED--YKKSITHYKRIN-----------GDNDYTLLEAELKTGRTHQLRAQLN
HLGHTIVGDTKYGK------N-----IKEDI-----------MY-----LFSYYLKIDLY
-----DLELE-------LRIPNFFLKKYNIQ--K--------------------------
---------------------
>NZ_ADBD01000013.1|c1|155840-156547|-|ZP_06080638.1|pseudouridylate_synthase_LSU_rRNA-specific
------------------------------------------------------------
------------------------------------------------------------
-----------M------------FDILFTHPDFLLINKHPNVSVHKDDG----------
----DTMLLQEVVTQTGD-GQLY---L--VHRLDKMTSGILLLARNAAAASELSQGFAM-
-----RKVEKFYLAIGSKKPKKKQGLICGDMERSR----------------RSSWKLL--
---NSQS------NPAVTQFFS-----------ATAALGERLFLCKPHTGKTHQIRVALK
SIGSAIVGDPIYNT------IE---------G-------ADRGY-----LHAFALRFTYQ
---GEVYQWLCDPRQF-PHLGTKWHEDAVNQ--GVENWLSPWDLPWPALKVGAKG-----
---------------------
>NZ_ACIQ02000013.1|c1|353441-354499|-|ZP_06598559.1|pseudouridine_synthase,_RluA_family
---------------------------MRELRIGENEAGQRLDKLLRKYLR-RAENGFLY
KMLRKKNITLNGRKASGKELLKEGDLLKLFFSEESFQKLCAPLT----------------
-PLPEEKKREEGRAKAEWEGEAFSSRIVYEDENLLLFNKPAGLLSQSDGS--------GL
PSVNELCLSYLMEKGELGREQLASFRPGAANRLDRNTTGLLLFGKTLPALQELSFCLKK-
-----RTIGKYYLAVVRGHT-PERGRIEGFLRKDP--------------DKNRVFLQE--
---EASG-GA---KEVQSEYRRLFAGE------SGEQISFSVLLVHLISGKTHQIRAHLA
SVSHPILGDPKYGD------RDLNRLLQKRTG-------LRSQL-----LHACELHFPKL
-PEDSRLSYLSEKNFYASPPRSFLPFLPKKY--RLPEGSRLF------------------
---------------------
>NC_013515.1|c2|1575200-1576069|+|YP_003306741.1|pseudouridine_synthase,_RluA_family
---------------------------MKKYILNEKAFRLKVSQYLREFHN-YSGRS---
--LRSIEVFLDNKQIRTTTKLPKIGILTVI----------EKEK----------------
-GSNIVPIKMN-------------LDIVYEDDDLLIVNKEPYLLTHPTLKKVDKTLANG-
---IVYHFIEKYNKNLVP---RF------ISRLDMNTSGLIMIAKNSFSQSFIQSGKAN-
-------VTKKYLALAENMFEKEEIIVEEKIYKDG--------------DELAR------
---IIDD-RG---QYAKTKFKLIK---------NYPHLDISLIECELFTGRTHQIRVHLK
HLGHPIIGDSLYNP---------DSIFNK--I-------AKRQM-----LHSYKLSFTHP
-SSGKRIDVE-------IPIYHDMLDILKI------------------------------
---------------------
>NC_013947.1|c3|2108220-2108984|+|YP_003510778.1|pseudouridine_synthase
------------------------------------------------------------
---------------------MTGEDW---------------------------------
-------KSIVD------------KYALVDNDQVLALNKPTGISVMGE------------
---RHDTDVARLAAE-AG-DKLH---P--VHRIDKATSGLVLFARDLKCHGVLTRQFNK-
-----RTVDKTYLAVVNSAEVPAAARIDLPLSVGRKNRVRVAAPREAITNTGTDW-TVPE
TDVFTHV-KT---YPSVTEYDTL-----------WTGDGLSLLAVRPISGRRHQIRVHLA
WTGFAITGDSLYDK------NPA-----------------TRML-----LHSWRLAVEAP
WLGGERTTLEA------APGPDFWEPLP-----GVDAATVLPGVTPDQRR----------
---------------------
>NC_005027.1|c3|3427166-3427936|-|NP_867282.1|ribosomal_large_subunit_pseudouridine_synthase
------------------------------------------------------------
----------MPDSKFALADSPIGGETFFI------------------------------
----RDSRNMSE------------VDVIYEDNHLLVVNKPTKLATMGAAG---QPTLHS-
---LGCDYIRRTCNKPNK-VYLG---I--VSRLDSMTSGVIVMARTSKAASRLTPQFANH
S---GDGAKKTYLAVVSGRVEQQQGTLVDDVYKDD--------------AAHRMR-VA--
---HHSRSDA---KEARLEYEVLG-----------CDRELTLLMVKPLTGRKHQIRLQWA
EVGFPILGDTKYGS--------------------------ERSWPTGIALHSWRLSIMHP
-TKKERMTFE-------APIPDAWASRLGTN--LLAKP----------------------
---------------------
>NC_008700.1|c1|1380060-1380836|+|YP_927008.1|pseudouridylate_synthase
------------------------------------------------------------
------------------------------------------------------------
---MAFADTAPA------------IEILYEDEAMVAIHKPAGLLVHRTYL-------AR-
---KEHWFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANSLCGQFAS-
-----HSIRKHYLALVRGNM-FDAGVLDYALKEEL--------------DELADK-DV--
---DPDK-PA---QEAITAYRPLLNSEIPYSSGRYPSSRFALMHLQPQTGRKHQLRRHMA
HLRHPIVGDTTHGD------GKQNRFFREHFG-------VNRLW-----LIAKRLELTHP
-LTGAPIAIE-------TELEPEWLDVFSGL--GWDEETLALSPSMLIA-----------
---------------------
>NC_008577.1|c2|3373305-3374159|-|YP_870457.1|tRNA_pseudouridine_synthase_C
------------------------------------------------------------
--------------------MNLDDDWLDMP------EDKFNPT----------------
-ESDEQSEPAPE------------LRVLYQDEHLVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAN-
-----HSIEKQYLALVRGNM-HESGVLDYALKVEL--------------DEVADK-FA--
---NQDK-AA---QDAVTQYEPLLNTEIPYPSGRYATSRFALVKLSPKTGRKHQLRRHMA
HLRHPIIGDTTHGD------GKQNAFFRTHFD-------INRLW-----LIAKKLTFTHP
-VTQARLSIE-------TELEPEWETVFSGL--GWDDAALCCEPSVLIAEQTTTV-----
---------------------
>NC_008322.1|c2|3214485-3215339|-|YP_738759.1|tRNA_pseudouridine_synthase_C
------------------------------------------------------------
--------------------MNLDDDWLDMP------EDKYNPS----------------
-ESDEQSEPAPE------------LRVLYQDEHLVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAN-
-----HSIEKQYLALVRGNM-HESGILDYALKVEL--------------DEVADK-FA--
---NQDK-AA---QDAVTQYEPLLNTEIPYPSGRYATSRFALVKLSPKTGRKHQLRRHMA
HLRHPIIGDTTHGD------GKQNAFFRAHFD-------INRLW-----LIAKKLTFTHP
-VTLERLSIE-------TELEPEWETVFAGL--GWDDATLCREPSVLIAEQTTTV-----
---------------------
>NC_008321.1|c2|3157324-3158178|-|YP_734778.1|tRNA_pseudouridine_synthase_C
------------------------------------------------------------
--------------------MNLDDDWLDMP------EDKYNPS----------------
-ESDEQSELAPE------------LRVLYQDEHLVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAN-
-----HSIEKQYLALVRGNM-HESGILDYALKVEL--------------DEVADK-FA--
---NQDK-AA---QDAVTQYEPLLNTEIPYPSGRYATSRFALVKLSPKTGRKHQLRRHMA
HLRHPIIGDTTHGD------GKQNAFFRAHFD-------INRLW-----LIAKKLTFTHP
-VTLERLSIE-------TELEPEWETVFAGL--GWDDAALCREPSVLIAGQTTTV-----
---------------------
>NZ_AAWY01000002.1|c1|211981-212808|+|ZP_01704397.1|pseudouridine_synthase
------------------------------------------------------------
-------------------------MWLDMP------DDELDHV----------------
-VLDNTDEQAPD------------IRILFEDEHIVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAE-
-----HSIEKQYLALVRGNM-HESGILDYPLKVEL--------------DELGDK-HA--
---RQDK-TA---QDAVTAFKPLLNTEIPYPSGRYPTSRFALVQLTPKTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNTFFREHFG-------INRLW-----LIAKKLTFTHP
-VTQTRLSIE-------TELEQQWETVFTGL--GWDDVVLSNDAPFLIAKN---------
---------------------
>NC_009438.1|c1|1518411-1519238|+|YP_001182866.1|pseudouridylate_synthase
------------------------------------------------------------
-------------------------MWLDMP------DDELDHV----------------
-VLDNTDEQAPD------------IRILFEDEHIVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAE-
-----HSIEKQYLALVRGNM-HESGILDYPLKVEL--------------DELGDK-HA--
---RQDK-AA---QDAVTAFKPLLNAEIPYPSGRYPTSRFALVQLTPKTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNTFFREHFG-------INRLW-----LIAKKLTFTHP
-VTQSRLSIE-------TELEQQWETVFTGL--GWDDVVLSNDAPFLIAKN---------
---------------------
>NC_008750.1|c2|3158378-3159220|-|YP_964135.1|pseudouridylate_synthase
------------------------------------------------------------
--------------------MNQDNMWLDMP------DDELDHV----------------
-VLDNTDEQAPD------------IRILFEDEHIVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAE-
-----HSIEKQYLALVRGNM-HESGILDYPLKVEL--------------DELGDK-HA--
---RQDK-AA---QDAVTAFKPLLNAEIPYPSGRYPTSRFALVQLTPKTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNTFFREHFG-------INRLW-----LIAKKLTFTHP
-VTQSRLSIE-------TELEQQWETVFTGL--GWDDVVLSNDAPFLIAKN---------
---------------------
>NC_011663.1|c2|3422299-3423162|-|YP_002358820.1|pseudouridine_synthase
------------------------------------------------------------
--------------------MNQDDIWLETP------ENALNAS----------------
-QEDDSEAQAPE------------IEILYEDDHLVVIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAS-
-----HTIEKQYLALVRGNM-HESGILDYALKVEL--------------DELGDK-NA--
---DPNK-AA---QEAVTAYEPLLNTEIPYPSGRYPTSRFALVRLSPKTGRKHQLRRHMA
HLRHPIVGDTTHGD------GKQNAFFREHFG-------INRLW-----LIAKKLSFTHP
-VTQVRLSIE-------TELEPEWETVFAEL--GWDEAILSQQAELLIATDEIPAGNA--
---------------------
>NC_009052.1|c1|1671758-1672621|+|YP_001049829.1|pseudouridine_synthase
------------------------------------------------------------
--------------------MNQDDIWLETP------ENALNAS----------------
-QEDDSEEQAPE------------IEILYEDEHLVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAS-
-----HTIEKQYLALVRGNM-HESGILDYALKVEL--------------DELGDK-NA--
---DPNK-AA---QEAVTAYEPLLNTEIPYPSGRYPTSRFALVRLSPKTGRKHQLRRHMA
HLRHPIVGDTTHGD------GKQNAFFREHFG-------INRLW-----LIAKKLSFTHP
-VTQVRLSIE-------TELEPEWETVFAEL--GWDEATLSQQAELLIAKDEMPAGNA--
---------------------
>NC_009997.1|c1|1772425-1773288|+|YP_001553905.1|pseudouridine_synthase
------------------------------------------------------------
--------------------MNQDDIWLETP------ENALNAS----------------
-QEDDSEEQAPE------------IEILYEDEHLVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGVLLFAKSSEVANALCEQFAS-
-----HTIEKQYLALVRGNM-HESGILDYALKVEL--------------DELGDK-NA--
---DPNK-AA---QEAVTAYEPLLNTEIPYPSGRYPTSRFALVRLSPKTGRKHQLRRHMA
HLRHPIVGDTTHGD------GKQNAFFREHFG-------INRLW-----LIAKKLSFTHP
-VTQVRLSIE-------TELEPQWETVFAEL--GWDEATLSQQAELLIATDEIPAGNA--
---------------------
>NC_014012.1|c1|1432081-1432959|+|YP_003555973.1|tRNA_pseudouridine_synthase_C
------------------------------------------------------------
------MMNWINSSVKQDKEDKQVSDMTQCK------LTDDNLV----------------
-GEETIEETPPE------------IEILFEDDDIVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDKVG-CHVF---P--VHRLDRPTSGVLLFAKSCEMANALCVQFAD-
-----KTIEKHYLAIVRGNM-HEAATLDYPLKVEL--------------DDLGDK-DV--
---NQDK-PA---QDAVTSYQPLLNTEIPFTSGRYASSRYALVKLSPHTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNKFFREHFS-------VNRLW-----LIAKQLTFNHP
-RTGERMIIE-------TELEQQWFDLFKGL--GWDEEALGSGTSYLLA-----------
---------------------
>NZ_ABIC01000024.1|c1|59764-60618|+|ZP_02158305.1|tRNA_pseudouridine_synthase_C
------------------------------------------------------------
--------------MNQDKQDKQVSDMTQLQ------QVADNLV----------------
-GEETIEETPPE------------IEILFEDDDIVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDKVG-CHVF---P--VHRLDRPTSGVLLFAKSSEMANTLCEQFAD-
-----KTIEKHYLAIVRGNM-HEAATLDYPLKVEL--------------DDLGDK-NV--
---AADK-PA---QDAMTSYQPLLNTEIPFSSGRYASSRYALVKLTPHTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNKFFREHFS-------VNRLW-----LIAKQLTFNHP
-RTGERMVIE-------AELEHQWLDLFKGL--GWDEETLASEASSLLA-----------
---------------------
>NC_009901.1|c1|3530330-3531184|-|YP_001502744.1|pseudouridine_synthase
------------------------------------------------------------
--------------MSDNTKNPSQSEQLDE-------SLLEQDL----------------
-CQDEEQEIAPH------------IEVLFEDDDIVVIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDLVG-CHVF---P--VHRLDRPTSGILLFAKSSEMANVLCEQFAA-
-----HTVDKEYLAIVRGNM-HEAGTLDYALKEEL--------------DELGDK-DV--
---DPNK-AA---QDAVTSYKPLLNSEIPFSSGRYATSRYALVQLSPHTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNKFFRSHFG-------INRLW-----LIAKKLSFNHP
-RSGERMSVE-------TELEAEWLSLFEGL--GWHEETLSLDAQPIIIA----------
---------------------
>NC_010334.1|c1|3633571-3634410|-|YP_001675196.1|pseudouridine_synthase
------------------------------------------------------------
--------------MSDETREVADSELLDI------------------------------
----EAEEIAPH------------IEVLFEDDDVVAIHKPAGLLVHRSYL-------AR-
---RERFFAMQLTRDKVG-CHVF---P--VHRLDRPTSGILLFAKSSEMANALCGQFAD-
-----HTVDKEYLAIVRGNM-HEAGTLDYALKEEL--------------DELGDK-DV--
---DPNK-AA---QDAVTSYQPLLNSEIPFSSGRYATSRYALVQLSPHTGRKHQLRRHMA
HLRHPILGDTTHGD------GKQNKFFRSHFG-------INRLW-----LIAKKLSFNHP
-RTGERIEIE-------TELETEWLQLFEGL--GWHEDTLSVDKQPLIIANGCKI-----
---------------------
>NZ_AAEW02000015.1|c1|44105-44989|+|ZP_01313369.1|pseudouridine_synthase
--------------------MAISRYCSKLVLPHAQPPYPDLVAFLAGYFPHVTYEEWAR
RVDDGKVLDADQQPLGRDGYRPQQVIYYYR------------------------------
-EVEEQPLIPFA------------ETILYQDDALLVACKPHFLPVHPGGR--------Y-
---VTENLVYRLRLATGN-DQLA---P--VHRIDRFTAGLVLFAQRSEDRARYNALFSQ-
-----GNIKKRYDAVAHCPEEPQQRHWQVANRIEQ----------------GDPWFRW--
---QVVA-GD---VNARSSIELLD-----------LRQGYGLFSLQPITGKTHQLRLHMS
GLGFGLVNDRYYPN------LLPE--QPDDF--------STPLQ-----LLAKEVIFTDP
-VTGKHHHFE-------SPRTLAWAF----------------------------------
---------------------
>NC_013929.1|c18|8154673-8155590|-|YP_003492892.1|putative_RNA_pseudouridine_synthase
----------------------------MRVRLPQGSAWATVRDHLVERLA--AGAGVID
GMLDAGLIVDADGRAVSRERAYVPGMSVWF------HRD---------------------
-LPHEVPVPFP-------------LDIVYRDDHIVVVDKPHFLATTPRGS--------H-
---ITETALARLRRELAV-PTLS---A--AHRLDRLTAGLVLFTVRPGERGAYQSLFRD-
-----RLVTKEYEAVAPYDP-----SVVLPCTVRS--------------RIVKER-GV--
---MAAR-EVEGEPNAVSGVELLD--------RRAGG--PARYRLLPRTGQTHQLRAHMA
SLGLPILGDPLYPL------VRDP--VPPGDF-------RRPLQ-----LLARALEFTDP
-VTGLAHRFVS------GRVLQAWSSYE-----TWAEPAPRTRPDGIS------------
---------------------
>NC_006361.1|c4|807653-808582|-|YP_116958.1|putative_RNA_pseudouridylate_synthase
-----------MRRRQQPPLPKRHGLDPARLRLPEAGEWATIRDHLVHRLPRVAPERIDE
LLRAGAIVDLDGPIAPDAPYVPGGAVWFHR------------------------------
-DLPDEVEVPFD------------LTVVHRDETVLVVDKPHFLATIPRGQ----------
---HIRQTALVRLREQLGLPDLV---P--AHRLDRVTAGLILFVVDPARRGAYQTMFHR-
-----RTVRKQYEAIAPFDP-----ELALPRVVRS--------------RIVKEK-HV--
---LAAR-EVEGEPNAETLVELLE---------HRDG--LGRYRLTPHTGRTHQLRLHMN
SLGVPILGDDFYPV------LTDK---PVHEF-------TRPLQ-----LLAAVLEFTDP
-VTGEPRRFET------TRSLQAWTDYP-----GWAG-----------------------
---------------------
>NZ_ADGV01000046.1|c1|31744-32688|-|ZP_06400263.1|pseudouridine_synthase,_RluA_family
-----------------MTSAFAADGDTRSLPVPDGLDGMRLDQAVSRLL--GLSRTAAA
GLIDAGDALVDGVAR-PNSYKVKAGSWLEV-------TLPAPAA----------------
-PPAVVPQAVPG------------LTVVYADDDIVVVDKPVGVAAHPSPG-WTGPTVIG-
---GLAGIGHRISTSGAA-ERQG---V--VHRLDVGTTGIMAVAKSERAYTALKRAFKY-
-----REVEKRYHAVVQGHPDPLRGTIDAPIDRHP--------------HHDYRW-----
---AVVS-GG---KPSITHYDTLE---------AFPA--ASLLDVRLETGRTHQIRVHFS
SMRHPCVGDLTYGA------DPT---LSARLG-------LSRQW-----LHARSLSFAHP
-GTGDEVTFV-------SEYPDDLARALEIL--RD-------------------------
---------------------
>NZ_ABQH01000179.1|c1|25060-25944|+|ZP_03536527.1|pseudouridylate_synthase
---------------------------------------MRVDTGLARLL--GLSRTAAA
ALAEEGAVELNGVPA-GKSDRLVSGALLQV-------RLPEAPA----------------
-PLQNTPIDIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVH-ERQG---I--VHRLDVGTSGVMVVAISERAYTVLKRAFKY-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GHEW-KF--
---AITK-NG---RHSLTHYDTLE---------AFVA--ASLLDVHLETGRTHQIRVHFA
ALHHPCCGDLVYGA------DPK---LAKRLG-------LDRQW-----LHARSLAFAHP
-ADGRRVEIV-------SPYPADLQHALKIL--RGEG-----------------------
---------------------
>NZ_GG663492.1|c1|105300-106226|+|ZP_06432738.1|pseudouridylate_synthase
-------------------------MADRSMPVPDGLAGMRVDTGLARLL--GLSRTAAA
ALAEEGAVELNGVPA-GKSDRLVSGALLQV-------RLPEAPA----------------
-PLQNTPIDIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVH-ERQG---I--VHRLDVGTSGVMVVAISERAYTVLKRAFKY-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GHEW-KF--
---AITK-NG---RHSLTHYDTLE---------AFVA--ASLLDVHLETGRTHQIRVHFA
ALHHPCCGDLVYGA------DPK---LAKRLG-------LDRQW-----LHARSLAFAHP
-ADGRRVEIV-------SPYPADLQHALKIL--RGEG-----------------------
---------------------
>NZ_ABLL01000101.1|c1|87893-88804|+|ZP_03420010.1|pseudouridylate_synthase
------------------------------MPVPDGLAGMRVDTGLARLL--GLSRTAAA
ALAEEGAVELNGVPA-GKSDRLVSGALLQV-------RLPEAPA----------------
-PLQNTPIDIEG------------MKILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVH-ERQG---I--VHRLDVGTSGVMVVAISERAYTVLKRAFKY-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GHEW-KF--
---AITK-NG---RHSLTHYDTLE---------AFVA--ASLLDVHLETGRTHQIRVHFA
ALHHPCCGDLVYGA------DPK---LAKRLG-------LDRQW-----LHARSLAFAHP
-ADGRRVEIV-------SPYPADLQHALKIL--RGEG-----------------------
---------------------
>NZ_ABOW01000101.1|c1|17848-18759|+|ZP_03432490.1|pseudouridylate_synthase
------------------------------MPVPDGLAGMRVDTGLARLL--GLSRTAAA
ALAEEGAVELNGVPA-GKSDRLVSGALLQV-------RLPEAPA----------------
-PLQNTPIDIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVH-ERQG---I--VHRLDVGTSGVMVVAISERAYTVLKRAFKY-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GHEW-KF--
---AITK-NG---RHSLTHYDTLE---------AFVA--ASLLDVHLETGRTHQIRVHFA
ALHHPCCGDLVYGA------DPK---LAKRLG-------LDRQW-----LHARSLAFAHP
-ADGRRVEIV-------SPYPADLQHALKIL--RGEG-----------------------
---------------------
>NC_010612.1|c13|2851113-2852024|+|YP_001850666.1|RluA_family_pseudouridine_synthase
------------------------------MPVPEGLAGMRVDAGLARLL--GLSRSAVA
VIAENGGVELDGVPA-GKSDRLTAGAWLHV-------QLPEAPP----------------
-PPENTPVEIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRISTSGVH-ERQG---I--VHRLDVGTSGVMVVALSERAYTVLKRAFKQ-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHP----------------GGEW-KF--
---AVTK-NG---RHSLTHYDTVE---------AFVA--ASLLDVHLETGRTHQIRVHFA
ALHHPCCGDLVYGA------DPK---LAKRLG-------LQRQW-----LHARSLAFAHP
-ADGRRVEIV-------SPYPPDLQHALDVL--RDEG-----------------------
---------------------
>NZ_ACFI01000117.1|c1|7434-8345|-|ZP_05217195.1|hypothetical_protein
------------------------------MPVPEGLAGMRVDAGLARLL--GLSRSAAA
ALAEDGGVELDGVPA-GKSDRLTGGAWLHV-------RLPEAPA----------------
-PPQNTPVDIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVP-ERQG---I--VHRLDVGTSGVMVVALSERAYTLLKRAFKQ-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GGEW-KF--
---AVTK-DG---RHSLTHYDTVE---------AFVA--ASLLDVHLETGRTHQIRVHFS
ALHHPCCGDLVYGA------DPK---LAKKLG-------LQRQW-----LHARSLSFAHP
-ADGRRMEIV-------SPYPPDLQHALDVL--RDEG-----------------------
---------------------
>NC_002944.2|c3|1331504-1332430|+|NP_960185.1|hypothetical_protein
-------------------------MTERSMPVPEGLAGMRVDAGLARLL--GLSRSAAA
ALAEDGGVELDGVPA-GKSDRLTGGAWLHV-------RLPEAPA----------------
-PPQNTPVDIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVP-ERQG---I--VHRLDVGTSGVMVVALSERAYTLLKRAFKQ-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GGEW-KF--
---AVTK-DG---RHSLTHYDTVE---------AFVA--ASLLDVHLETGRTHQIRVHFS
ALHHPCCGDLVYGA------DPK---LAKKLG-------LQRQW-----LHARSLSFAHP
-ADGRRMEIV-------SPYPPDLQHALDVL--RDEG-----------------------
---------------------
>NC_008595.1|c9|3329289-3330173|-|YP_882412.1|ribosomal_large_subunit_pseudouridine_synthase
---------------------------------------MRVDAGLARLL--GLSRSAAA
ALAEDGGVELDGVPA-GKSDRLTGGAWLHV-------RLPEAPA----------------
-PPQNTPVDIEG------------MTILYSDDDIVAVDKPAAVAAHASVG-WTGPTVLG-
---GLAAAGYRITTSGVP-ERQG---I--VHRLDVGTSGVMVVALSERAYTLLKRAFKQ-
-----RTVDKRYHALVQGHPDPSSGTIDAPIGRHR----------------GGEW-KF--
---AVTK-DG---RHSLTHYDTVE---------AFVA--ASLLDVHLETGRTHQIRVHFS
ALHHPCCGDLVYGA------DPK---LAKKLG-------LQRQW-----LHARSLSFAHP
-ADGRRMEIV-------SPYPPDLQHALDVL--RDEG-----------------------
---------------------
>NC_013194.1|c2|4485708-4486835|-|YP_003169101.1|pseudouridine_synthase,_RluA_family
MENPQKKKAPADASIKDSGPADYSANAGIALRVPTACGGQRLDQVLARLLS-QHSRSRLQ
DWIREGRVAVGGAVTVEPRFRLWGGETIAL-------TESTDER----------------
-AEASAPEEIP-------------LRIVFEDDTLIVLDKQAGLVVHPGSGNWRGTLLNG-
----LLHHAPQLARV----PRAG---I--VHRLDKDTTGLMVVAKTLEAQTDLVRQLQA-
-----RSVKRCYQALVRGIV-EGAGIVDAPIGRHP-----------------TVRTRM--
---AVVS-GG---RPARTHYRVLE---------RFVA--CTLIECALETGRTHQIRVHMT
SIAHPLVGDPIYGG------GASR--VPQGAV-------FPRQA-----LHACRLALVHP
-ASGKAMLWR-------SGVPADMAALIDRL--RLESLAAHGAEQLAEGADDEDDWDEGD
DRAEMIDLGDEDPDDGDLGEQ
>NC_010995.1|c3|3822906-3823868|-|YP_001983659.1|pseudouridine_synthase,_RluA_family_subfamily
----------------------MKDVVELSAQVPIQMNGMRFDQAASELFP-DFSRSRLQ
GWIKDGLLTVDGRVA-KPKDKLIGGETLAL--------HAELEA----------------
-QGDWEPEAIE-------------LDIIHEDDDLLIINKQAGLVVHPAAG-----NYTG-
---TLVNALLNHAPSLVNIPRAG---I--VHRLDKDTTGLMVVAKTLEAHTDLVAQLAD-
-----RSVSREYEAVAVGAM-TGGGTVDAPIGRHP--------------LQ-RKL-MA--
---VLSQ-GG---KRAVTHYRVAK---------RYPH--HTHIRVKLETGRTHQIRVHMA
HVGHPLVGDQTYGNRFKIPKGANQQLIEALKH-------FPRQA-----LHAFKLGLEHP
-GTGEYTEWT-------APLPADFRKLLDALDQGYQQED---------------------
---------------------
>NZ_AAMD01000203.1|c1|14336-15034|+|ZP_01466412.1|ribosomal_large_subunit_pseudouridine_synthase
------------------------------------------------------------
------------------------------------------------------------
---------MSE------------LRVLHEGAGLLVVAKPPGTLVIPGRG--------E-
---GDTSLREQLEAQLRR--KVF---V--VHRLDRDTSGALVFALDAERHRALSMAFEE-
-----GRVHKRYLALVEGRV-EAPRLVEEALVPAR---------------KGRMR-PA--
---RPGE-EG---KPSRTRIRPVE---------TFAQ--ASLVEAEPLTGRTHQIRVHLR
SLGHPLLVDHQY--------GRAEPLVRRELGGEGEAVVLSRTP-----LHAARIEWPPL
-PGVEAGAVE-------APLPGDMALALELL--RSVGE----------------------
---------------------
>NZ_AAQN01000001.1|c1|2614034-2615020|-|ZP_02243458.1|pseudouridylate_synthase
------------MTDPQPPTPPTDRVGVRILKVPEDRAGQRLDNFLLGQLK-GAPRSLIY
KLVRSGQVRVNGGRA-KAERKLEGGEEVRIPPVRVNEEGDKA------------------
-APPSSFMARLE------------AAIVFEDARLLALNKPSGVASHGGSG----------
----ISFGAIETLRALRPNQNLE---L--VHRLDRDTSGLLIVAKKRSALTELQALMRED
DRVEGRGITKRYLSLLIGRMPDGVMSVDAPLHIGL--------------RQGGER-HV--
---QVNA-IG---KPSLSHFKLLE---------RRGG--HSYCEVRIETGRTHQIRVHAQ
HLGHPVAGDDKYGE------ADVNKRLRDQLG-------LKRLF-----LHAASLEFALD
-AGQTPYVLS-------APLAPELAEALDQL--GR-------------------------
---------------------
>NC_003919.1|c1|2468719-2469705|+|NP_642429.1|pseudouridylate_synthase
------------MTDPQPPKPPADRVGVRILKVPEDRAGQRLDNFLLGQLK-GAPRSLIY
KLVRSGQVRVNGGRA-KAERKLEGGEEVRIPPVRINDEDDKA------------------
-APPSSFMARLE------------AAIVFEDARLLALNKPSGVASHGGSG----------
----ISFGAIETLRALRPNQSLE---L--VHRLDRDTSGLLIVAKKRSALTELQALMRED
DRVEGRGITKRYLTLLVGRMPDGVMTVDAPLHIGL--------------RQGGER-HV--
---QVNA-IG---KPSLSHFKLLE---------RRGG--HSYCEVRIETGRTHQIRVHAQ
HLGHPVAGDDKYGE------ADVNKRLRDQLG-------LKRLF-----LHAASLEFALD
-AGKTPYVLS-------APLAPELAEALDQL--GR-------------------------
---------------------
>NC_012779.1|c1|2276255-2277217|-|YP_002933783.1|23S_rRNA_pseudouridylate_synthase_C
--------------------MNTQNTSVKLVTIAADEAGQRIDNFLRNQLK-GVPKSMIY
RIVRKGEVRVNKKRI-KPEYKLEAGDQVRIPPVRVAERDEAPVS----------------
-ARLDKVAALNG-------------CILYEDDYLLVLNKPSGTAVHGGSG----------
----LSFGVIEGLRALRP-EARF---LELVHRLDRETSGVLLVAKKRSALRSLHEQLRE-
-----KGMQKDYLALVRGQWQSHCKVVQAPLLKNT--------------LQSGER-VV--
---RVNA-EG---KPSETRFKVEE---------RFAN--ATLVKASPVTGRTHQIRVHTL
HAGHPIAFDDRYGD------RDFDRELADT-G-------LNRLF-----LHAAALRFVHP
-HSGETLRVE-------APLDAALRHCLNAL--RARSALS--------------------
---------------------
>NZ_ABIC01000024.1|c1|64490-65449|-|ZP_02158312.1|RluC
------------------MNTEAPKPKVQLVTIDEDHLGQRIDNYLMTKLK-GVPKSRIY
RIVRKGEVRVNKKRI-KPEYKLQDGDIVRIPPVRVSDKSDRPGP----------------
-SAKLTKVSQLE------------DRIVFEDKFIIVLNKPSGIAVHGGSG----------
----VDFGVIEAMRALRP-TQKF---LELVHRLDKDTSGVLLIAKKRSALRHLHDQLRF-
-----KKMQKDYQALVKGTWQARDKVIKAPLLKLT--------------LKSGER-IV--
---RVNQ-EG---KECETRFKILQ---------RYQG--ATLVQASPVTGRTHQIRVHCQ
YAGHPIACDDKYSE------QRFDDTMRVH-G-------LNRLF-----LHAAQLRFTHP
-GTEEIMIVQ-------APLDPVLTETLDKL--VKA------------------------
---------------------
>NC_005027.1|c2|1131677-1132375|-|NP_864762.1|ribosomal_large_subunit_pseudouridine_synthase
------------------------------------------------------------
------------------------------------MVGTLGIA----------------
-STLIGDQDPAM------------IEILWQCHACVVVNKPVGLPTTSPKG------TDS-
---LESCLREQFAQAGNPVSYLT---A--VHRLDRPVSGLVLIALRKKAARLLSEQFRL-
-----RHVQKKYIAMVQGNA--LEACKQEPWHDTI--------------AKLTDE-ARVE
IVGLDST-DG---RQAETKVSFLE---------YDSESDTSRIELRPVTGRMHQLRIQSA
HRGHPIVGDPLYGT------AE---------D-------ESALR-----LVAAKLSFRDP
-TNGRAVEVE-------LPELPF-------------------------------------
---------------------
>NC_008800.1|c1|2854263-2854961|+|YP_001006830.1|putative_ribosomal_large_subunit_pseudouridine
------------------------------------------------------------
-------------------MSKIVDTFI--------------------------------
-----APLCHDK------------IETLYQDDHLVLINKPTGLLSLSGKN-------PQ-
---NLDSVHHRLVQIFPG-CTL-------VHRLDFGTSGLMVIARNKAINAALCQQFSQ-
-----RTVTKVYSALLCGHLDDNEGVIDAAIAKDP---------------ALFPL-ML--
---ICAT-HG---KPARSGYRVVERFYHELEDGRSLP--LTRVQLIPETGRTHQLRIHCQ
QLGHPIWGCDLYGG----------RLLPGTEQ-------TPRLM-----LHASELHFVHP
-ISEEWIKIS-------NASPF--------------------------------------
---------------------
>NC_012660.1|c5|4820605-4821240|+|YP_002873907.1|ribosomal_large_subunit_pseudouridine_synthase
------------------------------------------------------------
------------------------------------------------------------
-------MPLSN------------IHILYQDAAVLVVNKPTLLLSVPGRA-------DD-
---NKDCLITRLQENGYPEARI-------VHRLDWETSGIILLARDADTHRELSRQFHD-
-----RETEKAYTALAWGQPELDSGSIDLPLRYDP--------------PT-KPR-HV--
---VDHE-FG---KHALTFWKVLE---------RCGD--WCRVELTPITGRSHQLRVHML
SIGHPLLGDGLYAH------EQALA------A-------WPRLC-----LHASMLSFTHP
-QSGERLRFE-------CPAPF--------------------------------------
---------------------
>NC_013855.1|c3|989677-990357|+|YP_003450841.1|ribosomal_large_subunit_pseudouridine_synthase
------------------------------------------------------------
------------------------------------------------------------
----MTPAQIQD-------------RILYRDGLMLILDKPAGLPVHAGPA--GGPNLER-
---HFDALRFGFPKPPSL-----------AHRLDRDTSGCLILGRHAKALRKIGILFQN-
-----GKVDKTYWAVVAGGPPQDSGRIELPLAKIS--------------NKTGGW-RI--
---VGSP-DG---QSAVTDYVV-----------RGQADGLTWLELTPHTGRTHQIRVHCA
SIGCPLIGDPQYG-------GP---------E-------GKPLH-----LHSRAISLPLY
-PKRDPVGAV-------APVPPHMRAALEAC--GFSEIA---------------------
---------------------
>NC_009523.1|c3|3274329-3275228|-|YP_001276963.1|pseudouridine_synthase
----------------------------MPLTIPTTSPGALLCDALTAALG---DATEAL
WLIARGGVWVDGVRVRDPGMRLPADATIVV---------QRPPD----------------
-GIYREPVVTPE-------------MILYEDDDLIALNKPIDTYVEATPW-------DAE
GHLRAALARFLALRNGTA-PPLH---L--AHRLDRDTSGVLLISKTPDVNAALQRVFRD-
-----GAAHKTYLAICAGLPSFDEIEIETGHGRGR--------------GGMFRV-FPPE
AIGRTLP-QGGTVKSMRTRFRVVR---------RLDD--AALVRAWPLTGRTHQIRLHLA
FLGHPLIGDSKYGG---------LSIWRGTPA-------FHHH------LHAERLELPHP
-QSGAPLVIV-------AP-APEWAQ----------------------------------
---------------------
