>NZ_ACHJ01000147.1|c1|4711-6172|-|ZP_03979536.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------VSPQ-----QAFNSVREFHTSY-------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------P
RTLNVNSVESHP----------------------------WELTLDSLQVWSDG--T--Q
VHLCD--EDGSPLRFRPTSMVGVG------AYPEWLMQIAMAA-TGSTPNINWSWGTISD
HVD---YLPGVRHG-RVIVSRPAFRYRGLE--------------------DVNAFNEWA-
-DSHGISEWVRMGDSDRKILLKRTAPGFSE-AVRSQLR-----RSDGWVYESFDS-----
ELTPLVRDHQDRPIFSEICLT-FGISSPAPDPDA----LRT-----TAQSLSVVATNQDK
ELIPGI--SDTANLTIVPRDGFRERVIRRLFSTEETAAG---------AYFIRYPT----
DSG--ESGLRLRYPRRT----------STGAAVETAIREMTSSG--WLLGLEEKAHSLEF
ERYGG-PAVFPLFAELFSLESRVVAHLSA------------ASSTDTIDERLHLPILDRW
LNL-FPDYRSV-----IVEFAVQS-EDSSTVQKAASALLREADSLGDL------------
------------ASADLIDP---------------------SIRAHM---KSLANKI---
-----SAHSVGTYELQSAAHLFCNRV-G-ISTDREKALWAALSKIERRNHHANDTHPHRS
RAS-----------
>NC_013730.1|c6|5101205-5102188|-|YP_003389014.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------MNWNEHFAANL-
------------------------------------------------------------
---------------------------HNTTLGPRTWLSGHIFYTDDLTHLIIDSLFCWA
E---------------------------------------------------TLRKQEII
EGFFFIRYAENGPHLRLRLLGQ-------------------PDKLLAEAV----------
------------------------------------------------------------
-------------------PFLEEKTKI-------------------YFIQRPSKKVITR
LSEWY----------PNDSLVWIAYEPE-IDRYGGPIAIRLAE-----------------
------------------------------------------------------------
----------------------------------------------------------KH
FQASS--------------------------------------ETIGRGI-ASAELTYSH
S--------------------VG-----------------LAIQLHAVY----------S
FFMLDT------------------------------------------------------
------IAERIDF-------------------------------------WNTFTANW--
-SMYMLKTQNLKNTSNYNMLLDTYNKYEAI-FDKQKLA----------------------
------------------LTPFFS------------------------------------
--------NLWIMLNTQSDFQES-------------------------WYM---------
----------------------------------DWIEHMRQHR----------------
------------------------------------------------------------
------------------------------------------------------------
------------RDIDVLVQ----------------------SGQMK---TPYTTNP---
-----LSIAGRQYLLHSYIHMSNNRL-G-ISNYDEGYIGYIMQKLLSTC-----------
--------------
>NZ_ACUY02000006.1|c1|159152-162421|+|ZP_06162153.1|lantibiotic_biosynthesis_protein
--------------------------------------MTVEGSFSPLAAARHFTLRTAA
R-----PLRLAPAENDVLLAAAGRESL---------------------VEYIRDAYRDP-
AFAQAVIHAAPALWESVQRALGDPASM-----KPNRLRRVALSTRKFLNRISSRPTPFGL
FAGVSAGEFAGDPENSRVRFTQGR---REAVADFR-WLSPVVRSLEQRPEVLKGLTVCRN
PLLRWRANEILVFGA--------DRADVSQSRTAIGRTPVLDCVLDKCGGNDGIAVEDLC
EGVAK-EFH-ASPGGVLGLVARLVGLEILYTSLRPKLTGGDPLEEVVRSL-----QRAGV
DA---------------EGLLDIHRRIRAL--SGPATADDAGEEYSRTYAAMAE------
------VDG--ADKADGAGNRIHFVLNS---GVQL------------RLPDRIRQD-AEE
GMHILQRLSHM----RLGMRGLRKYHMDFLERYGIERTVPLLTLVDPARGIGV-PE-DYS
WPKQVSEKKPPSPDEVNEK------------------------REERLAALYSKALAEGG
REIGLTEA---DIDELSHGPFDESE-----CQLAAELYLNLAARSWSRLAE-------GD
YRVSLGSNPGTHSSLCTTGRFLGLLPEMNEDPELR--------PFVDDEREYSASLSYYP
RSHAATNLVNTRPLGVKLIG-VDTPH-------AAGT---DYVPLSRIGVKATM--D--G
LFPVDM-SDGRAVRIHSRNSVYTP--AQAPNAVRFLADME--T-ELQRLWEPWDWG-RLG
YFP---FVPRVRHG-RFVLSPARWSLKELK----------RSGFLKGSD-CLETFNRWK-
-ERWGVPRHCLAVTMDLRLLLDTENPGDVE-LLQAELA--K--ADNLVLEELPGGAQTPR
DAWGWLSDG-EDVYVSELVLS-FKRRDAAS--------AFA-----PERFLLGVDATPEL
RYLPG---SQWHSFRLYTPADEITHLLKGKIGEAVERIAEAGGATP---FFVRYI-----
DGV--GSHLRVRFQNSS--E---SDGQGQSAEFEGILREICEGA--GATTFVQDGYVPEF
ERYGG-VDLLDTTHDVFSEDSLAVLKALRGP---S------CDLFSGLEEYVVLSWTETF
VKF-FQGFG---------SALDETGMDEAVEAADSPEAIGDAAEAIDDPIAILETWTRKM
GLASSRGDESYDRHRERWSEIVRSHLLRDQRGDDSLRRHGLGRTAPFLAGKGFADVV---
--AAGNAHVSAFRIVGSYMHMTFNRVFG-PDQANEQRLLGILRSVAARLSRERSAREAAN
ERG-----------
>NC_013440.1|c9|2024740-2025813|-|YP_003265936.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MPQPP
LPGTSET--------------------PIAEVDTARWL---------------------S
HHLFTAGDR---------------------------------------------------
--------------------------NALLTQIVGPAAVELLDGGIIDRF----------
------------------------------------------------------------
------------------------------------------------------------
----------------------------FFIRYAENG-----------------------
------------------------------------------------------------
--------------------------------PHLRFRVRLAADVEPALAA-------EK
TLAALRRPRQPR-------------------------------PQEGDAE-THAPLVLDP
GDIRPAE---------FELE-------------------------------TER------
-------YGGPAHFPHSLEFFVLS----SLDAVEFVT----------------NWGSKRR
SVQ-----------------------------------------------LVETLTRLA-
-----------------RYALGFARDREEL-LALADYA----------------------
------------------------------------------------------------
--------AHW----------------REQMAPIVARA----------------------
-------------------E---SMYEHNGAALSQRIQAVLNQA--ALPG--------DD
DAEGDAGPAAANPLQVSVAHAQTLAASVD--------------DLDDTRRRTVLGSQLHM
AANRLGLTNPE-----EV------------------------------------------
------------YLSVLLSR----------------------CLEGL-------------
-------YACPEDLDAALLSRSAAPTPSEAARGLTELAERGLRQLVASHAVAAAPE----
--------------
>NZ_DS570404.1|c1|42330-45542|-|ZP_04999344.1|conserved_hypothetical_protein
--------------------------------------MRTSDPMNLYTPAGYFLLRTPT
L-----PFTPYAQALDGTGAA-----G---------------------RDRIREVAGQP-
LVRQALRVASDSLAEQLR--------------KDARDDRTDASLLRYVSRMSSRPTPYGL
FAQVAAGEFGPRTSLTRTGARPAA---TRTRADMG-WLEQLVQQIEDDRDVRPGLTVVLN
PLLQRSHDRLTLPVSH-------SLRPTDQRVSSVRITRAVETVLDRAAT--RPTWAELT
ARAAR-DFPAVPAARIDALLDRLWDLRMLTSDLRPPMTHPLPETAVLDRL-----AGLAG
AE--------R----YRGALGRTRDLAARA---DAAPPEHAERLLAELQTYQRT------
------LVPGHTE------SPLQLDARAALATDTTAAAAATVTDPAATLSAAVADA-AAD
AADVLLRLGHH-----TRDTALAAYHEHFLDRYGSGAEIPVLELLNPETGLGA-PD-GYH
FPARELPLELGPRPRPAT-------------------------GRSALTALAAAALHQGA
TEVELTDA---FLAGLPSANGGGAG---PRPRPGLDVLGQLMAESRQDLDT-------GR
WRFVLT-TGAVRDGGRIGARFFDLLGEDFGRRMKRYAEAE---EARCPGV-LFAELNYRP
LHSRGGNIAIHPSVRSHEIC-VNTEP-------TAGV---GQIGLDDVLVGATS--E--R
LYLRSA-AHDQELKVTQSHLFNW---STAPNVCRFLLEVS--Q-DGWAALAEFEWGDLLE
AAD---FLPRVTRG-RVVLKPARWRFGPGAPGFP---AGLASGTPEAER-FFEIFQKWR-
-RDWHVPRWVNLAMLDNRLLLDLDSSVCVA-EIQRELRSTAPHKGGNLIMEEALF---DP
LRPQWLRDGAGRSYTAEIAVPLLARNTAAGAAVPVAPATAV-----AAGRTAARRPALAK
HQLPG---GDWSHLKLYAAASRHEDLLTGEVPRLVHGLREEGLIDR--WFFIRYA-----
DPH--P-HLRIRVRRRP--G---AAPHAAMNRLVDWAGDLVGHG--PARDAALISYDRET
ERYGG-PVALEALEAVFEAGSDMTTAVLAL----L------RDRPGMELDVVGALALHRL
YEA-WGHQDGA-----PADTAPHH-TVEARDREAFRAVRTTLCDLVAP----------WD
ARPDARARQWAPDLDRLLAI----------------------QDQAVRQAGDLVRRL---
-ARAGELTGTEQDVLGSLAHMQSNRLLG-IDRTRELRSHSFRALALRAVRGRP-------
--------------
>NC_009921.1|c3|1601904-1605104|+|YP_001505690.1|lantibiotic_dehydratase_domain-containing
--------------------------------------MDIRGGPLACAPLDAALFRAAV
M--SDESAKALAAGSWPGANCDDVDRW---------------------CTWLADVWAQP-
AVAEAIDTASPALAVGVEDACRGSRP------SVRRVRRLGLAVARYLVRMSRRATPFGL
FAGVAPLRFDVEPVLRWTGSDR-----PYPRVDSV-WLAAVVARLESMSSVRAALTVVAN
DLAMVRGERLVVPWRPHAHP---PTETFLPAEVSVRHGRPVQAAVASAAA--PVRFVDLV
DSVVV--ALGLSRPGVEEMLAQLLTCGVLVSSLRPPATCTDGVAHLLDALNGIENTRVPA
ATDRTDDSTSDPSHGLVGDLRMIQAELGAA---RDADSSLGRPRLAALRERMRA------
---VCAVVE----------QPLAVDLRL---DCTA------------VLPELVAVE-AAA
TAGALLRLTPH----PAGNPSWRDYHHRFLAKFGESALVRVDQLVDPVIGLGY-PA-HFG
VAEPPPTGGVSP-------------------------------RDEYLLQLAQRAAFDGQ
QEVVLDEA---ALDTMSAQTAGSWP------EPHAEICVEVLAPSMAALSQ-------GA
FTLLV--TGVSRTGAAMSGRFLDLLPEADRLRMIDVFRRL---PPTAEGA-VPVQLSFPP
AHARLENVTRTPHVLADWVS-LAEHR-------DSQR---GRLPWTDLAVTAND--E--Q
LHLVSL-SRGAVVEPLLTNAAAR---QTFPPLARLLHELP--R-ASSGAVAPFSWG-AAS
CLP---FLPRVRHG-RAVLAPARWRINPSD--LP-------GPGAGDQE-WADALARLR-
-ERSGLPRWVSTGRADVRLRLDLDERMDRD-LLRAELD--R--AGALTALEAPGP-----
DDYGWADG-----RAHEIVVP-VATTAAPRPA------PAI-----VTTPGPMPVSDATS
GILPG---SRVLFAKLYCHPDVVSTILTDHLPALLDAWGVPPQ-----WWFIRYR-----
DPA--S-HLRLRLHVAPDADGVTDSYGRAAARVGAWAEQLRARR--LIGDLVLDTYHPET
ARYGD-GEALVAAEHLFAADSAAVVIQLAAQ----------NANRALHPAALTAVSMVDL
TCA-LLGGRQT-----GMRWLLEN--RRASGAPTQRPVLRQAIALSRTCDDEPAPNAAIP
QLPA--------PLRAVWGV----------------------RRRAA---ERYAAQL---
--AALPGLPASSEVLGSLLHLHYVRSHG-IDSSAERTCHRLARAVALAWHNTGQHPPLDL
ARAEGP--------
>NC_009953.1|c3|681963-684992|+|YP_001535521.1|lantibiotic_dehydratase_domain-containing
----------------------------------------------MFRSVDAATIRIAA
H-SWPDSPAPWPGRSGASGIA----------------------------YWLQATWRKV-
GLAEAVWAASPEFAARVEAVLASGSA------APDRGWRMALALARYLVRAQRRATPFGL
FSGVATLRFDTVAAVVPAGQPAIR-----VRPDAS-WLASLIARLEADPDVHRRLPVQAN
NLALVNGSRIVGARR--------PHASARTESTSVRSTAAVRLAMSLTPT--PLPWAELV
DAVAA-AFPGFPRASADAMVAGLVDHGVLISALRPPSTCTDPIRHVLDTLDAMFDGAPGG
QR--------A----LRAELRSLHDRLGGT-------SAGSTTYLCGLADDMRR------
------VAP--AT------QPLAVDLQL---ADQV------------ALPEQLAAE-IAA
SVEVLRRLTPD----PAGRPEWCAYRARFVDRYGMTAVVPLARLVDPLVGLGF-PA-HFA
TVADAPVALLSD-------------------------------RDERLLAMAQQVVIDGA
REVVLDDA---AVEWLAGTGRVTGS-----VSPHVDVSAEVRAVSLEALTQ-------GR
FTVAL--TGMGRSAMATSGRFLDRLPYADRELMCREFARL---PVAVAGA-MPAQLSFPP
RKLHSQNVLNSRQVLPWLVS-LAEHR-------HVAE---NVIGLDDLGVTAGC--D--R
LVLVSM-SRRRVVEPTVGHAAAV---HTMPLLGRFLLELP--R-ATDARLKPFDWG-AAS
CLP---FRPALRYG-RVLLAAARWRVDPAA--LP-------GAEAGDDE-WLTAWEALR-
-TRLRLPAWVQVGNGDQRLRLHLDQSMDRA-LLRAHLD---ASAGPVTVVDAASP-----
EDFGWLSG-----RAHEIVVP-VASTVAPAAA------PAA-----VTARGAWPPPAPPE
PIIPGA--SGLLSASVAVEPSTMELVLMRGLPALFADWPEPPL-----WWFVRLR-----
RST--P-HLRLRLH-----T---DDYGDAAVRVGRWVAGLRQQR--LAGDWSLDTYHPES
GRYGC-GTALAAAEELFAADSTAALAQLV-----A------QPESGIDRQALTALSMVDL
AAS-MLGSRTD-----GCEWLVAR-PEQTGQAPIQRAVLRQAVTLDPG------------
KLPE--------PIQQAWQE----------------------RSRAA---TRYAAEL---
--SAVAGPLTPASVLASLMHLHVVRALG-PDEDAEQLTYRLARHVALAAVRRRVRAVGAS
R-------------
>NZ_ADBZ01000079.1|c1|3222-5876|+|ZP_06220825.1|Lantibiotic_dehydratase_domain_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MRPDAE-WLASLIARLETDPNVRNGLFVQAN
NLARVSGLRIIVQCRP-------HASAPVDGVSSVRRTEAVRLAMSLSAE--PVRWTELV
EKIAV-GYREFPRASVEALVAGLVEQGVLISALKPPSTCTDPIKHLLDQL-----DAAPH
IG-----YVGQ----TVEQLQALQRRLGAT--------AGQAIDLRGLAARMRE------
------MAV--GT------QPLAVDLRL---ADEV------------VVPHQVTAE-VVA
SVEVLRRLTPH----PEGRPEWRGYHARFVDRYGMAAVVPLAEVVDPVAGLGY-PE-HFD
GADRATPLSG---------------------------------RDERLLVLAQQAVLDGI
REVVLDDA---AVRALAGPDHDEDS-----VSPHVDVSAEVRAVSLRALEE-------GQ
FLVVV--TGMGRSAMATSGRFLDVLPYAERELMRGKFARL---PVAVEGA-MPAQVSFPP
RRLHAQNVLRSPQILPWLVS-MAEHR-------PVAG---DVIGLDDLGVAAGA--D--R
LVLVSM-SRRRVVEPTVAHAGAV---HTMPLLARFLVELP--R-ALDARLKPFDWG-AAS
CLP---FRPAVRYG-RVVLSAARWRIDPAR--LP-------GADASDGE-WSAAWAALR-
-ERLRLPRWVQVGSGDQRLRLDLDQAMDRS-LLRAHLD--ATSDGAVTIVEAAGL-----
EDFGWLSG-----RAHEIVVP-VASTAAPAAV------PAA-----VAARGSWPPPVPAG
PVLPGS--SGLLSGSLAVEPSMVELVLWRGLPALFADWPESPM-----WWFVRLR-----
RPY--S-HVRLRLH-----T---DDYGDAAVRVGRWAAALRRQG--LAGDLRLDSYRPET
GRYGD-GRAMSAAEELFAADSRAAVAQVA-----A------KDDSPLDRRALTAASMLDL
AAA-MLGSRDD-----GCEWLVAR-PAHPGRAPIDRGVLRQAVTVDPT------------
SVPE--------LVQRAWQE----------------------RSRAA---SRYAAAL---
--SASGSPLTPAQVLTSLVHLHFVRAHG-PDDAAEQVTYRLARHIALAAVRRRARTAGAG
R-------------
>NC_007777.1|c9|2156428-2159652|+|YP_480926.1|lantibiotic_dehydratase-like
MPTIRDPGGSAAPRSAIPRATPSEVRDSDLASGPQVAGLGARASDALYRVAGPGVVRVAE
P-MPGLAALPWPDLGDGGEET---ERW---------------------CQWLREAWACA-
PFAAAVQAASPVLARRIAQVCAGGDL------PARQARSAVLSLMRYRLRLVSRATPFGL
FAGVGPARPGTALTVYEDP-THHR---MLARVDTA-WLFDVLDQLEGVPGVLDVLPVRAN
DLAFVRDGRLVLPFEGPRAG---SDAEVSTAETSVRYTQAVAAVMKAAAG--PVLVGTLA
AQLGT-EFPAAPARVLRGMLSTLVERRFLLSGLRPPSTELDPLGAVLATLRAIGADPVPE
AA--------D----LVDALRRRSRGLADITEPWTSQPATPDTAAPTSSPSGRR------
-------------------PPIALDMRA---GVGL------------ELPRLLLRE-VEA
AVDLLVRLAPA----PRGNAAWRDYHDRFLERFGAGAFVPVNSLINCETGLGL-PA-GYR
GTTLGPATAGPLSD-----------------------------RDALLLALAQTAAARRD
REVTLDAE---SLALLRTSDAVGWT-----CQPHTELRFRLHAADRRAVER-------GA
FDLAV--EGVSRAAGTTLGRFLDLANEADREEMTSALRAL---PTRQPGA-LLVQLSGGT
LSATAANVSRAPRILDHLIA-LGEYQ-------PPDR---GMIPVTDLAVTADG--S--G
LWLVSL-SLGRPVEPVAFHAVELT--RHGHPLLRFLSEIG--T-SRAAPCAPFSWG-AAR
RLP---FLPRLRHG-RTILAPARWLLAPAD--LP-------GPDATFAR-WSDDLAAWR-
-DQWGVPDQVFLGSDDRRLLLDLTEPAHLH-LLRADLG--R--ATRATLREAPPP-----
DAAGWIGG-----RTHEIVLP-LAAPPTPT--------AEV-----PRPRRPARIATSAD
AHLPGD--GAWLYAKLYAQPDRQVTILTERLASLWEHWDTPPL-----WWFQRYQ-----
DPA--P-HLRLRIRLID--P---DGFGDAARRVGRWATALRQAG--LLDQLQFDTYLPET
GRFGG-ASTLAATETLFAADSTAALAQLA-----A------SARGATHPHALVAVSLLDL
AAGCLPGDDAA-------RWLVEQ-LPRTQGPPIDRAQHDAAVHLADP----RESQATMH
TLPGGK------EILTAWAR----------------------RRARL---ADYQTAL---
--TSAGDGLTTRGLLPTLMHLHQFRMTG-PSVQAERDCARLTRAVALSVLRRREMA----
--------------
>NZ_DS570630.1|c1|58767-61844|+|ZP_05003917.1|conserved_hypothetical_protein
--------------------------MNRGARPTAAGHHAPRWEPPVYEYLDASLLRAGA
W-ASNDLAQPWPDPDGDTSS------W---------------------RAWLERTLRIP-
GFAEALEQASPALAQRVQGIRDGKEL------PAPAVRKATFAVLRYLLRASSRATPFGF
FAGVAPVWIG-DAAGVRIG-TGHR---AVVRPDAV-WLAEAIEHLEADRALLPLLAVQAH
ALVVEKDGHLVLDHRGP------GSAGGAPARVQVRATPPVRSALDAARR--PIRVADLL
SELAG-DFPRVPTEVIGKLLADLTAQRFLTTNLRPPITATNPLNHLLGALEAAGAERVPT
TT--------A----TVARVRALADTLSRP---------RTGEHWAGLASG---------
-----------SG------PRPGIDLRI---DGEA------------TIPTAVADE-AAR
AATVLVRLARQ----PFLSRAWSSWHGRFLERYGPRALVPVLDAVDGDTGLGY-PA-GFL
GGPPAPADTPLTE------------------------------RDGKLLVLAQNAALRRQ
HEIVVDDV---VIAELDESGPDTGV------QPTTELIVRVSAPSTKALAD-------GE
FTLAV--TGVSRTAGTVTGRFLDLLDPDDRDRMAKTYAMA---ATATDGT-LPVQISAPP
LHTSTENVARVPPVMPALLT-WGEYH-------DPDG---EQVPLDDIAVTADV--H--R
LYLVSR-SRQRPLEFVTLNAVEPV--HRTHPLIRFLTEAT--H-AMSTPCAVFDWG-AAT
TLP---FLPAVRHG-RTTLSPARWLLTTAD---------LVGREADQPA-WDTSLAVWR-
-EQVGAPSTAYVGDGDQRLRLDLDEPAHRV-LLRAQVQ--R--SGTAVLRADAAP-----
-DTGWIGG-----RPHELVVP-LTRTGPG---------QKA-----PWWLDRATGTANGY
GHLPGC--DGRFLVKLYARPERHGGIL-RRLPELLAELGGTTR-----WWFLPYR-----
DPD--E-HLRLRLVVP---A---DHAVGAPAAIGGWTRALRRAG--LISRVRWDTDFPET
ARFGG-PTAIDAAEGFFAADSEAAAAQIAS----S------AMAGGPPAQALTAASMLDL
TTG-LIGNPAD-----AMTWLINR--ARTTSTAPARDVYEQAVALGNP-----YDHGVLT
RQPGGE------RITATWAR----------------------RRKSL---AEYKAVL---
---DTAGTVQADVLLAELLHLHHTRVAG-IDLDAEGQCLHLARAAALSWTARGRTGS---
--------------
>NC_007777.1|c11|2390630-2393725|-|YP_481136.1|lantibiotic_dehydratase-like
----------------------------------------------MYQHLDSLVVRAAV
N-PPVDVAERWPDLVGPAATP---ESW---------------------RLWLREVMQNR-
AFEMALEQASPVLARRVREIRDGRQV------PQAGVRRAVLSVMRYRLRASGRATPFGL
FAGVAPVRVA-DHASVRAG-VAHR---AVARVEAG-WLCAVVDRLEADPVVRARLDVVAN
NLVFERDGHLVLEHRAA------GGTDGVPTRVQVRAHAPVRAAMGIGRR--SVRFSDLA
ARLAS-EFAPVPADVVDRLLADLVAQRFLLTNLRPPMTASDPLRHVVGVLQTTLNGGPVT
VE------AAW----VAERLNGIVDGLRSH--DSASSWTVARSSRERLGEDMAE------
------VHP--SA-----EPALRVDLRM---DWAL------------AVPRAVAVE-AAA
AAGVLVRLARR----STLSSGWDAWHGRFLERYGPCALVPVFDAVDPEIGLGY-PA-GYA
GSPAPAGVTFTD-------------------------------RDAKLLALAQNAALRRE
REIVLDDR---MISDLTVVDQDAHV------QPTTELTLRVHATSTRSLDD-------GA
FTLAV--VGVSRRAGTTTGRLLDLFDAKDSARMRALYAGL---PTASRDA-LSVQISAPA
RYTNTDTVGRAPQIMAHRLS-LGEYD-------DSEDG--DSLPLDDIVVTADV--H--R
IYLLSL-SRRQLVEPVALNAVEPV--RRAHPLARFLAEAP--A-ALSVPCAPFDWG-VAA
QLP---FLPALRHG-RTVLSPARWLLGTAD--LP-------GSAAGWTE-WDRALASWR-
-EQVNLPSAVYLGDGDQRIGLDLSEPAHRV-LLRSHLD--R--SGAALLRAAPDT---DA
A--GWVSG-----HAHEIVVP-LAAVAAP---------AAT-----PGWFSRAQVVGRDH
GHLPGC--DARFSVKIYAGLGCQDDILTRHLPHLVHELNGQQAAGEARWWFLRYH-----
DPD--D-HLRLRLAVT---A---DGVAPTADRIGAWTQRLRRAG--LISRAQWDTYFPET
SRFGG-TAAMDAAEAYFAADSAAALAQLAA----S------REKSGPDRRALTAASMLAI
VTG-LIGDTAE-----ATSWLISH--TRTEPSAPARALYQQTVALANP-----ADPRALA
AQPGGE------HVLSCWAH----------------------RREAL---TAYRHVL---
---QETRAEAPTSLLPDLLHLHHVRMAG-VSLAGERACLHLARAAALSWTARTRNPS---
--------------
>NZ_ADGX01000049.1|c1|44919-48017|+|ZP_06413705.1|Lantibiotic_dehydratase_domain_protein
----------------------------------------------MYQHLDTVVVRAAV
NPPADAVDEQWPDLVGPAATP---ESW---------------------RLWLREVMQNC-
AFEMALEQASPVLARRVQEIRNGRQI------PEAGVRRAVLSVMRYRLRASGRATPFGL
FAGVAPARVA-DHASVRAG-AAHR---AVARVEAG-WLCAVVNRLEADPAVRARLDVVAN
NLVFERDGHLVLEHCAG------GGTDGAPTRVQVRANAPVRAAMGIGRR--SVRLSDLA
AGLAS-EFAPVPTDVVDKLLADLVAQRFLITNLRPPMTATGPLRHVVGVLQATLDGGPVT
AE------TAW----VAERLNGIVDGLRSH--DSAPSWAAARSRRERLGVDMAE------
------VHP--SA-----EPALRVDLRM---DWSL------------AVPRSVAAE-AAA
AAGVLVRLARR----STLSSGWDVWHGRFLERYGPCALVPVLDAVDPEIGLGY-PA-GYA
GSPASPEGVTFTD------------------------------RDAKLLALAQNAALRRE
REILLDDR---MVSDLTVIDKDDRV------QPTTELTVRVHAASTRSLDE-------GA
FTLAV--VGVSRRAGTTTGRFLDLFDAQDGARMSALYAGL---PTASRDA-LSVQISAPA
RYTNTDTVGRSPQVMAHRLS-LGEYD-------DSEGG--GSLSLDDIVVTADV--H--R
IYLLSL-SRRQLVEPVALNAVEPV--RRAHPLARFLTEAP--G-ALSVPCAPFDWG-AAA
RLP---FLPALRHG-RTVLSPARWLLGAED--LP-------GSAAGWTE-WDRALASWR-
-EQVNLPSAVYLGDGDQRIGLDLSEPAHRA-LLRSHLD--R--SGTALLRAAPDA---DA
A--GWVDG-----HAHEIVVP-LAAATAQ---------AAT-----PRWVSQAQAVGRDH
GHLPGC--DARFSVKLYAGLGVQDAILTHHLPHLVDELNGQATGEAR-WWFLRYH-----
DPD--D-HLRLRRTVT---T---DGVGPAADRIGAWTRRLRRAG--LISRAQWDTYFPET
SRFGG-TAAMDTAEAYFAADSVAALAQLAA----S------REKYGPDRRALTAASMLAI
VTG-LIGDTVE-----ATRWLISH--TRTEPSAPARALYQQTIALANP-----ADPRALA
AQPGGE------DVLSCWTH----------------------RREAL---AAYRHVL---
---QETRAESPTTLLPDLLHLHHVRMAG-VSLPGERACLHLARAAALSWTARTRNPS---
--------------
>NC_007777.1|c5|1340702-1343791|-|YP_480236.1|lantibiotic_dehydratase-like
----------------------------------------------MYRSLDVPLLRMAV
V-PTDVDLPPWPDLDDTTDGA--VAGW---------------------TDWLRDIWARP-
VFADAMRLASPSLAARVASVFDGQCH------DRRTARRAVTATARYVLRMTGRATPFGL
FAGVGPADFG-PRARVRLG-DDHR---VHARPGGA-WLAALADDLEAFDTLLRRLPVTAD
GIPVARGDRLFIGPVARSGD---DAGPESVVEVSVRRTRAVEAALLHAVS--SLPVPELV
ARLAA-DKPAPAAGQIETMVIELVRRRFLHTPLRPATTITDPLSEVADQLAAARIDDLPP
LA--------G----RLNVIRDLQDLLAHH---DNTRSASHRRTLRTQAETLQR------
----RVVPS--AD------PDLDVGLVL---NADV------------VLPAAVAEE-AGA
AARALARLTGP----TAVPPEWADWHEAFLERYGPAALVPLLEAVNPDTGLGL-PA-TFR
GSTRSHRPRGNAA------------------------------RDQRLAALTQRAALDGA
LEARLGDA---AIAALAGDTAPDRV------PPHAELIAEVHANDLPALSR-------GL
FTLRV--TGGGRAAATTTGRFLHLLDPASFDRFRDIYAAL---PTMRAGA-TAAQVSCPP
LPAATVGVARSPRLTDTVIT-LAEHH-------DAGP---CVLRPADLAVGADA--E--G
LYLVSL-PDRRLVEPSAAHAVEFQ--YHTHPLTRFLCELP--T-ARVAVSIPFSWG-AAG
GLP---FLPRLVHR-RTVLAPAHWNLTAAD--LP-------SRAESAQE-WREALARWG-
-GTIPVPTRVQLVETDNRLRLDLHVDAHLA-LLRDHLH--R--HGSARLDEDAAP-----
EAFGWLAG-----HAHELVIP-LATTAAPLP-------GPA-----PERLAATVPAARSD
AQLPGV--SPWLSARLYGHPDRATDLLAR-LHDLLDAWPDPPA-----WWFLPYR-----
DTE--P-HLRLRLAVNE--P---GGYGLAATRLGTWAAVQREAG--LLSHLHLDTYQPET
GRYGY-GPAMTAAEGVFSADSAAALAARR-----L------AASARLSVGALTVAGLVDM
AIA-FTGALST-----GMRWLRDV--LPHEPARVPRAERTTTLHLANP----ADSFAHLR
AVPGAD------AVLSAWQP----------------------RATAL---AAYRDAL---
-----AAQRPPDQALASLLHLHVVRTLG-LNPAAEQTCIALARATAARALATTEATVS--
--------------
>NZ_ADGX01000188.1|c1|6086-8425|+|ZP_06417290.1|Lantibiotic_dehydratase_domain_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MAERNLATLRTVTVVTN
ALGYRRGGVWVLPCA--------RAEGSQVWDVEIDLTDPVRVAVETASA--PIPFRELA
AKVAD--DHASDTAAAERLVTALVQAGVLLSAVRPPMTVTDPAAHLTRHI------ALPD
SG----------------------------------------------------------
-------------------ARIAVDLRV---DCSV------------TLPPTVVRE-VRE
AASVLVAVAPH-------LPGWAAYHRAFLERWGPGAAVPLREVLQV---LGF-PA-GYR
GSPRRDPALFTA-------------------------------RDSLLASLAQQSVLDGC
TEVVLDDD---LIGSLRGGDDRPPI-------PHAELRFTLAAETAHDLER-------GA
FTLTV--VSGARHAGVAAARFLHLLTPAELDRFRGVYAGL---PTALPGA-ATVQVSGPP
LDTRLAAVARTPELLP-VLP-VGDFH-------PD-----PPWMLDDLAVAGDG--Q--R
LWLVSR-TTGQPVEPLLFNCVLLP--TAQQPLVRFLTEIW--T-AWTAPCARFTWG-HAR
ALP---FLPRIRRG-RSILHPARWTLPANA--LP-------ARTAPWPQ-WKAAWQQYR-
-EHRRLPREVLIGDDDMRLRLDLDENAHLT-MLRSDLD--R--HGRITLTEAGGR-----
--PGWIDG-----RPAELLLT-LTRT------------PPP-----DCPTTRPVRPASTL
QHRPGR--SRWLDTRLYGHADH----ILARLASLSELPAG--------WWFLRYP-----
HPE--P-HLRLRIPLRD--T---GRFADVAHDLALWAQRLHNDG--LLADYTLATYRPET
-RYGH-GPTLAAAEAVFAADSHAVLGRLA-----------------GDRQATTAAGMITI
AQG-FTGD--------GARWLVDH-APHRSGPRLEPTQLAGA------------------
------------RLPYEDDH----------------------LATAL---ATYRTLA---
----VQDGLDVDQLLADLLHLHHARMIG-ADTASERHCLRLARAIALTDLARRATP----
--------------
>NC_009921.1|c23|8215996-8218743|-|YP_001510995.1|lantibiotic_dehydratase_domain-containing
----------------------------------------------MYQAAHAALIRAAS
Y-PRDLTLPTWPDLTANQADE-----W---------------------LEWLREVWALP-
EFAAAVGQAAPDLADQITHVLAQESM------PARRVRRLVETTVRYLLRWTTRPTPFGR
FAGVAPLAFG-PRAAVWWG-DQHH---EVVRLDDR-SVAEYTAVTERDLAVLRGVTVMTN
TLGYRRGGVWVLPCA--------RVEGDRVWDVEINLTAPVLVAVEKARA--PIPFRELA
ATVAE--DQAIGTAKAERLLGALVGAGVLLSAVRPPMTVTDPAAHLARHI----------
---------------------------------ALPNPG---------------------
-------------------ERSAVDLRV---DCSV------------TLPPAVVRE-AQE
AAAALVAVAPR-------LPGWAAYHSAFSERWGPGAAVPLREVVGI---LGF-PA-GYR
GSLRRDAATFTA-------------------------------RDALLATLAQRSALDGC
AEVLLDDD---LIGQLRSEDDRPPI-------PHTELRFTLAAGTLQDLDR-------GA
FTLTV--VSGARHAGVAGGRFLHLLTPTELDQFRSIYTSL---PTALPGA-DAVQLSGPP
LDPRLATVARTPELLP-VLP-VGDLH-------AD-----PVCTVDDLAVAADG--Q--R
LWLVSR-LTGRPVEPLLFNCVLLA--THQQPLVRFLTEIW--T-AWTAPCARFDWG-HAR
TLP---FLPRVRRG-RSILHPARWTIPAEA--LP-------ARTATWPQ-WRAAWHQHH-
-ERRQLPQEVLIGGDDVRLRLDLDENAHLA-VLRSHLD--R--HGRAVLTETDGP-----
--SGWIDG-----RPAELLLT-LTRT------------PPA-----HRLAARRARPVSVP
AHRPGR--SRWLDARLVGQADH----VLARLSEFPGLPAG--------WWFLRYP-----
HPE--P-HLRLRIPLRG--I---AQFADVARGLAGWAEQLHDDG--LLADYTLATYRPET
-RWGC-GQTLAAAEAVFAADSRAALTWTS-----------------GDRQAGTAAGMIAI
AGG-FTDDGA--------RWLVEH-APHGGGSRLEPAQIAGA------------------
------------RLTYGDEA----------------------LTATL---ATYRTLA---
----ARDGLDLDQVLADLLHLHHARMIG-PDLASERHCLRLARALAQTTLARRPS-----
--------------
>NC_008278.1|c10|2950457-2953204|-|YP_712916.1|hypothetical_protein
----------------------------------------------MYQAANVALIRAAS
Y-PRDLRLPAWPDLTANQAGE-----W---------------------LEWLREVWALP-
EFAAAVGQAAPELAAQITHVLAQEPM------AARRLRRLVETTVRYLLRWTTRPTPFGR
FAGVAPLAFG-PRAAVRWG-DQHH---EVVRLDDR-SVADYTAAAERDLATLRKVTVMTN
TLGYPRGGVWVLPCA--------RAEGDQVWDVEIKLTDPVRVAIEKARA--PIPFRELA
ATVTD--GQATATAKVERLLAALVGAGVLLSAVRPPMTVTDPAAHLARHI----------
------------------------------------------------------------
-----ALPN--PG------ERIAVDLRV---DCSV------------TLPPAVVRE-AQD
AAAALVAIAPR-------LPGWDAYHSAFSERWGPGAAVPLREVVGV---LGF-PA-GYR
GSRRRDAAMFTA-------------------------------RDALLATLAQGAALDGC
AEVVLDDD---LFGRLRSEDKRPPI-------PHTELRFTLTAETLQDLDR-------GA
FTLTV--VSGARHAGVAGGRFLHLLTPTELDQFRNVYAEL---PTALPGA-DAVQLSGPP
LDPRLATVARTPELLP-VLP-VGDLH-------PD-----PVCTVDDLAVAADG--Q--R
LWLVSR-LTGRPVEPLLFNCVLLT--TRQQPLVRFLTEIW--T-AWTAPCARFDWG-HAR
TLP---FLPRVRQG-RSILHPARWIIPAEA--LP-------ARTAPWSQ-WRAAWHQHH-
-ERRRLPREVLIGGDDVRLRLDLDENAHLG-VLRSHLD--R--HGHAVLAETDGP-----
--AGWIDG-----RPAELLLT-LTRT------------PPA-----HHPPARPAHPVSIL
AHRPGR--SHWLDARLHGHTDH----ILTRLGELPGLPTG--------WWFLRYP-----
HPE--P-HLRLRTPLCG--A---ARFADVAHDLAGWAERLHNDG--LLADYTLATYRPET
-RWGR-GPTLAAAEAVFAADSRAALAW-----------------PSGNRQGATAAGMITI
ADG-FTGDGA--------RWLVDH-APHGGGPRLEPAQLAEA------------------
------------RAPYGDDG----------------------LTAAL---ATYRTLA---
----ARDGLDLDQMLADLLHLHHARMIG-PDLASERHCLRLARATVQTDLARIRS-----
--------------
>NC_013131.1|c10|4470099-4472288|+|YP_003114660.1|Lantibiotic_dehydratase_domain_protein
------------------------------------------MSPRLYHSADAVMLRAAA
R--VAVPLPPWPFAPDGQREV-TVEQW---------------------RAWLAEVWSDT-
ATAEAVQYASPVLAERVQAAVGGAVL------SAKRARRAALSLAGYAVRASSRATPFGT
FAGVTSAAFG-PATSVRVG-LHHR---AEGRMDPI-FLQAAITRLESDCVLMAEVKVCAN
TLCRVHDGRLIAP-------------ASGTSEFSLRLTGALELVLEAAAV--PLTCAELA
GKLAA-QFPIATAEHTAKLLEDLLHHRVLVSELHAPATDPDPLGHLLTVLTAAGADRSAS
AA--------A----LLHDLEDLRQAVAGI--GDALDADERSQRSRAALHAMNR------
-----AVPE--AG------GHPGVDLRV---DVDV------------TLPAEVASE-IET
AATWLTRLAAY----PAGTPAWAKYKAAFADRYGEDALVGVLDLTDPDTGLGF-PV-ETA
PATSG--------------------------------------RDRALLALAGTAALEGT
RRIKLTAD---LVNTLEAAAGGPAN----QIGPHLEMCVQVLAVSAEAINR-------GQ
FRIRV--LTASRAAGAMAGRFLPLLDPGDRLRFTQLYASL---PTVQEGA-AAAQLSFPP
ARIAADLMTRTTPILPTVIS-VGEHR-------PIG----GVLRPEDLAVGLRD--G--R
LFLACR-ATGQPVEPLATTAVNLRMPVHTAPLARFLAEIA--R-SGCAQVTGFDWG-AAL
ALP---FTPELHAG-RTTLIPARWRVEAAE--LP-------GRQASLTE-WTRELHALL-
-HRRRAPLRLTLAEADQHLQLDLETGVHAA-LLRQAVH--R--ASHATLLDSPPA-----
DGNGWIGG-----LANALLVPMIAT-----------------------------------
------------------------------------------------------------
ENR--P------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------
>NZ_ADBZ01000021.1|c1|78679-81792|-|ZP_06218015.1|Lantibiotic_dehydratase_domain_protein
-----------------------------------------MLPQRTFEPVGPALVRAST
D-PGNLGPEPGPDLIGPAAST---EAG---------------------LAWLAGQWSRP-
DVRDAISIASPHLARRVDQLLAADASGT----TAAAVRRAVLATCGYLLRWQRRTTPFGL
FAAVTTATVG--PASATFG-DKHR---AVARVDGE-WLTCVVDRLEAHHALRRRLFVVAD
SAAVVRDGRVIVAAWPPVG----QRTPGMLRETSTRNTAAVRLALQVAAW--PIRFDRLL
AQIMH-EVPHVAVATVEAMLHGLIDGGFLITNLRPPMTAVDGLTHVIDALHSAEAAELPQ
VT--------A----SLDQLCAIRQELARH--DAQVDGSEAMLIRAAVTEPMTV------
------LAP--NA-----EHQLAIDVRL---DAQI------------SLPPPVLAE-AAL
AVDLLLRLSTQ----PFGSVAWLDYHARFRDRYGPGALVPVRDLL-ADSGLGY-PT-GYL
GAPRARPAWRVITE-----------------------------RDTHLQALIQQAILDNT
GEIHLTDA---DIEALTVGDHHTAV-----RPPRVELAFAVHATAADAIDR-------GE
FTVQV--TGAPRTPSSMAGRFSYLLEPTEQEQVTASFST----RGRDADEELAVQVSFPP
RLPRNQNVTRVGRILPFVLP-LSEQP-------DW-----PDISLDDVAVTADS--E--Q
MYLVHQ-PTGRRIVPHIPHALDTI--VQTPPLARFLAEVA--D-ARSIAFGPLDHGAAAR
NLP---YIPRIRYR-RVILAPARWLLNAAD--IPPHTPPGAGDTEGR---WDAALTEWR-
-RRWRVPARVVACQNELQLPLDLDSPLDRA-LLRARLG--G--AERLELREDAPA---DG
Y--GWTGG-----HPAEFLSA-MT--------------PTA-----PPARRLPVTAPPGD
TLRPGT--STFIHTQIAGNPARFDELLTTHLPRLADRLAGLGLQR---WWIRRDRDTIRV
EAD--Q-RLSLFLRLNE--P---AAHAAACAILAEFAADLARRA--LPAQLIFAPYHQHP
ARYGH-GPAQHAAEEVFAADTTAAIAQLR-----T------AEQTDIPAQALAAASMARL
AAA-FAPDPDT-----GYGALLAC--LQQAAAPAERTITDLARRLADP----TTDYRSVR
ALPGGD------AIADAWRA----------------------RDHAL---SAYYERL---
-----LPQRDPTTVLRTLLHEHHVRAVG-VDPDFERATNHAARAAAMRCLAAADTR----
--------------
>NC_013510.1|c7|5259048-5262176|+|YP_003302206.1|Lantibiotic_dehydratase_domain_protein
-----------------------------------------MAVSRRFRHTGLVLVRATT
C-PPDVTPPGDVDLADHAAVA---REG---------------------AAWVRRVWQRR-
EVREAVEMSSPDLAAGIERLLTDGCP------AGRRLRRTVASPASYLLRWERRATPFGM
FAGVTAAALG--PAAVKID-TGHR---AVVRADSE-WLATLIDQVERHPALRMRLTVVAD
NTGVVRDGRFIVLRRAAVG----ARSPGPLQEASVRLTTPIAYALEQAVR--PQRLAALA
DRMSR-RFPSADTGRIHTLLHGLIDGGFLITDLRPPSTAEDPLNHLIQALHRAGVREAGD
AE---LTEITK----LLDHLEVINRQLMEH--NTAADPARAAPLRAAAAGRMRH------
-----LARG--TG------PVLAADLRL---NAHI------------AIPEPVVHE-AER
AADVLLRLSTQ----PFGTTAWLDYHARFRARYGTGALVPVRELV-TDSGLGY-PR-GYL
GAPRARPVWRTLTQ-----------------------------RDTTLMGMIQQALVDGR
EEITLSEA---DIAALTTGDHGDVV-----VPSRIELGITLHATSTDAINR-------GD
FTLQV--VAAPRAHTSMIGRFAHLLDKADRAKLART-------YAPDDDV-VVAQLSFTP
RRPHNDNVVRVAPHAGTVVLPLAEHPGTAPGRSGSGGTEVGVLSLDDLAVTADA--D--Q
MYLVQR-STGRRVRAYIPHALDTT--VQTPPLARFLAEIA--D-ARSAVFGPFDLG-AAR
ALP---YVPRIRYR-RTVLSPARWLLTRGA------------LAAPGED-WDAALHRWR-
-HRWRVPARVVLCQGELRLPLNLDRPLDRR-LLQARLN--A--AERLELREDASS-----
IAWGWVG------RAAELVIP-MV--------------AAA-----APKGRPPVTAPPGI
IHQPGD--ALLLRAHLVGNPAHFDTILTRHLPAFVQQLGVPIRR----WWASRHRDLIRL
EAD--Q-YLVVLFRLAE--R---SQYGAVAARLAAFAQELRTRG--LLEQLFLAPAAEQP
GRYGH-GPALEAAEEVFAADTAAAIAQIA-----M------AQAAGVAAQAVAAASMTHL
AAA-FASDTAA-----GYRTLVRR--AKRRSGPVDAVVRDAAFRLADP----AAGFAAVR
ALPGGD------AVAAAWQR----------------------RADAL---AAYHRLL---
-----AQQRDPADLVTTLLHGHHVRAFG-PDPEHEATTIRPARAAALRNLATASPAAGAP
--------------
>NC_008278.1|c18|6900335-6903463|-|YP_716479.1|hypothetical_protein
----------------------------------MRRDGIAMTVSLRFQHTGAVLVRATT
D-PGDLELPTWLNLSDPAAVE---QEG---------------------RAWLAKIWVRP-
EVREALQLASTALAARIDQLLDEGARPH----TAKEMRRAIVSVASYLLRWQRRATPFGL
FAGVGAAALG--PAMAEVG-AGHR---AVVRADAE-WVTTLIDQLERRPELRPRLTVVAD
NTRTVRDGRVIVHSRAEVG----ASSPGPLRESSVRLTRPVQVALAAAGS--PIRLDALA
ARMTT-RFPSASPGKIRMVLDGLVDGGFLITSLWPPMTAVDALAYLICALRSAGGEDLAD
LG--------A----LLHELDDISAQLACH--NSTSNLEQAAKIRNAVIGQMTA------
-----LVPV--AG------HALAADVRL---DARI------------AVPERVLTE-AAL
AASVLLRVTTQ----PFGSAAWLDYHARFRARYGPGALVPVREMV-ADSGLGY-PT-GYL
GAPRARPAWRMLTE-----------------------------RDAALLALIQQATVDGA
EEIELTDA---DIEALTIGEHADIV-----PPQRIELGVEVHAVSTEAIDR-------GD
FQLRV--TAAPRAPTSMAGRFAHLLDDADRARLAATFTAEP--EAGAPDGAVAVQMSFPP
RRPHNENVVRVAPLLPDVVS-LSEHP-------ESTHPDVRVIEVDDLAVTADA--D--Q
MYLVQR-STGRRVIPRVPHALDTV--VQSPPLARFLAEVA--D-ARSARFGGFDLG-AAR
VLP---YVPRIRYR-RTVLAAARWILTAAD--LP-------GPPAGGGA--QDALGSWR-
-QRWRVPARIVLCHGELRLPLDLDQELDRA-LLRAQAE--R--AGRVELQEAGPA-----
GCEGWIG------RPAELLIP-LT--------------AIT-----SPARPLPATAAPGA
VLRPGD--SAVLHAQVVGNPARFDEILTAHLPRFLDDLDGLVRF----WWVRRHRNLILP
ESD--Q-HLAVFLHLGS--P---EQYGPAAAKVAAFASELEARG--LPCQLTLASHPQHP
ARYGD-GPALAAAERVFATDTAAAIAQIA-----T------AQASGVPAQALAAASMAHL
AAA-FAPEPES-----GCRALVAC--LRQEHGPLDRTLRDHALGLAEA----DGRYRAIR
TLPGGD------AVAAAWAA----------------------RDTAL---TAYHRAL---
-----AEQRDPAAVLRTLLHEHHVRAIG-VDPTHERETGRLARAAALRRLARAGAR----
--------------
>NC_009921.1|c1|69424-72531|-|YP_001504430.1|lantibiotic_dehydratase_domain-containing
-----------------------------------------MPMPPRYQHTGFIQVRAST
D-PGGLDLPTDLDLSDSAAVEQE---G---------------------RAWLAKTWARP-
EVREALRLASADLCARIEQILDDGAGRR----SGAEIQRALTAVASYLLRWQRRATPFGM
FAGISTATAG--PATAEVG-RAHQ---AVARADAE-WVTALADQLERHPELRGRLTVVTD
SARIVRDGRVIVHRRAEVG----APSPGPLRESSVRLTRPVFFALAEAGN--PIRLDALV
ARTAT-RFPTASPDKIRALVHGLVDGGLLITSLRPPTTGVDALTHLADALRAAGLEGLAD
VS--------D----LLREIDCLRAMLAAH--NRITDPQPAAQTRRTVAARMAS------
-----LAPG--AG------QMLAVDTRL---DANI------------AVPGRVLTE-AAL
AASVLLRLSRQ----PFGSTAWLDYHARFRARYGPGALVPVRELV-AESGLGY-PG-GYL
GAPRARPAWRMLTD-----------------------------RDTALLALIQRAAVDGA
EEIALTDA---DVEELAVGERGDVV-----PPQRVELGVEVWAVSTRAIDR-------GD
FRLRV--TAAPRTGTSMAGRFAYLLGPADRDRLAATYAASA--EAGERDQPLAAQLSFPP
RRPHNENVVRVEPLLPAVIS-LSEHP-------DPAHAKVRLIDLDDLVVTADA--A--Q
MYLVQR-STGRRVIPRIPHALDTS--VQSPPLARFLAEVA--D-ARTAVFGGLDLG-AAR
VLS---YIPRIRYG-RTVLAVARWTLTSTD--LP--------RGQSGDG-RQEALCAWR-
-QRWRVPARVVLCHSELRLPLDLDRHLDRV-LFLTRLE--R--AGRIEVQEDGPP---DA
Q--GWIG------RPAELLIP-LT--------------AIS-----PPARPLPVTAAPGA
VLRPGD--AAVLHAQLVGNPARFDDILTGHLPRLADSLEGLVCL----WWVRRHRDMILP
ESD--Q-HLAVFLRLRS--T---DHYGPVAAAVASFAADLETRG--LPGQLTLASSPQHP
ARYGD-GDALAAAESVFAADTLCATAQIT-----A------AQTSGISAQALAAASMVDL
AAA-FAPDPLA-----GYQALVGC--LRQEHGALDRTLRDQALDLADP----GGNHQAVR
ALTGGE------AVVSVWNA----------------------RAIVL---ASYYQAL---
-----ARQRDPRTVLRTLLHEHHVRAVG-VDPTLEKETGRLARASALRHLALAGAR----
--------------
>NZ_CM000913.1|c9|5091892-5094948|+|ZP_06773862.1|Lantibiotic_dehydratase_domain-containing
---------------------------------------MTATTGAGHRWQGVALLRATT
S-TGTADLPRTLDLDNTVLLQ----------------------------GWLARIWQRD-
DVREALRFTAPVLCETVEAVIEGRQT------QARKIRRAVLSIASYLLRWQHRPTPLGL
FAGTAPLLVG-PDPSVSWG-TKPK---ATVRADAD-WLTEIIQRLQASPGLRDRLPVMAN
APVRIRDDRLVAPGSPADA----YASHLAPEEIAVWNTRSLAAAMEAARL--PIPYRELR
ECLRT-RFPRAAAGQIDTLLQELVSHHLLITSLWAPMTTVDAFGHLCTELRKADAETVDE
VR--------E----TVQELYAIHAELSRP-RSDRTTLGATIARMQTVSSVTRT------
--------------------PVLLDTAL---DCEV------------RIPQLVVDE-VQR
AVAALYRITPQ----PYGYQHWRDYHHEFLAEYGTGTLVPVLDLV-SDTGLGL-PA-DYT
GSVRERAPKQLTD------------------------------RDGILLRMVQETVMAGR
DELVLTDAMTETLAKAVGTDDRTLV-------PRVEVAFEIHSASTTALAR-------GD
FQLLV--TGVPRPGSSMAGRFAHLLPTEHREALAAT-------FTDNTGA-VATQLSFAP
RRRRNENVARVPHLLSHVIP-LAEHR-------EPED---GSIPLTDLAVTADD--R--S
FHLVQI-STGRPITVRVPHALEAA--VQTPPLARFLAEIA--T-ARHAVYKPFDYG-AAA
RLP---YLPRVRYR-RTVLTPARWLLAAQD--LP-------SQTATTKE-WDHAFDAWR-
-ERLRVPEHVTMTEHDQRLPLDLTHSVHRH-ILRTHLD--G--ADRLVLRESPGT-----
DAYGWMG------RAHEVWLP-LHTVPGED--------DSE-----RPARISTALVSEGE
AHLPGA--GTVLRARIYAHPRRYDAILVRHLPRLVGRFGSAPPM----WWFTRRS-----
DVT--P-HLDLVLHIEP------GTYGTGAEHVHEWARSLHDKA--LVSNLTLTDFRPHP
GEYGH-GPALDAAHQLFAADSATVLAQIRFT----------DQNPDLSPQALAAASILDL
VQK-FAATPEH-----GEEWFIEH--TPQGSGRLDRSLREQALGLSTP-----GDRAALS
ALPGGT------EVVEAWTT----------------------RATAV---RAYRRAL---
-----IDQREPLTAARSLIHQHHARALG-PDTTTEAATLRLARTTALHHRHRRQTR----
--------------
>NZ_DS570516.1|c1|115942-119076|+|ZP_04991806.1|lantibiotic_dehydratase_domain-containing
---------------MGRAKRFARPTGPLPSRAASWKGLMASRAAAGYLWQGVAMLRATT
S-PGPADIPRTLDLDNVAVTR----------------------------GWLNRIWQRE-
DFRSALELATPVLSDAIEAVVRGRQT------EPRHVRRTALSTVSYLLRWQHRPTPLGL
FAGTAPVSVG-PRASARWR-DKHR---ATIRPDAE-WVTDMVLRLQRTPALLERLPLVAN
NAARARGDRLVAPGPPSDG----HAVLLAPVEISVRNARPVAAALDAART--PIPYRGLH
GHLRD-LFPQATPEKIDALLASLVEQRFLITSLWAPMTTVDAFQHLCRELDGLQADNIPE
VR--------D----LVHELYALRDELSAH---QPTLSDTSVSTVATRMRALTP------
------VTP----------TPLLIDTAL---DCET------------TLPQAVIAE-AQA
SVSALYRTTPQ----PYGYQHWRDYHRRFRARYGVGALVPVMDLV-ADSGLGL-PA-GYV
GSERGAALKVRTD------------------------------RDELLLAMMQQVLLDGG
RELRLTDD---MVDALEKAAGKDER----LFVPRVEVAFEVHSSSTRALSS-------GA
FDILL--TAVPRPGSSMAGRFAHALPPEHQDALAAT-------YHGAPNS-LTAQLVFPP
RRHRNENVTRTLRLLPHVIE-LSGHQ-------ETDA---TTIPLADIAVTVDP--R--S
FHLVQL-STGRRIDVRVLHALEGG--TQTPPLARFLAEVA--N-GRFAAYKPFDFG-AGS
RLP---FLPRVRYR-RTILTQARWLLMADD--LP-------GRKASIQE-WESAFAAWR-
-DRLRAPEQVAMIEYDQRLPLDLSHPVHLR-VLRAHLD--N--TRRLELRELPDA-----
DAHGWIG------RAHEIWLS-LGRSE-----------PAA-----EVPRPRTAPSAAPD
RHLPGA--GDVLLAQLHAHPRRYDEILSRRLPSLLAAFGDAPPL----WWFTRHREMARP
DAD--Q-HLDLTLHLP---P---DAYGAAAQHVRRWADSLHGTG--LAAGLVLAPYQPQT
GRFGH-GTAMDAAHRVFAADSAVALAQIQLT----------ERTDALAPQALAAASALHL
VTP-LAPDTAA-----AEEWLVRN--LPQGTGRLNRALRAQVLELAAP-----NGDSVLA
ALPGGP------AVVEAWRA----------------------RAAAV---DTYRTAL---
-----TDHRDPLDVARSLLHQHHVRALG-VDPRAEETTIRLVRTAALQHRRAAR------
--------------
>NC_010572.1|c15|4507619-4510684|-|YP_001825359.1|putative_lantibiotic_dehydratase
---------------------------------------MVTRAVADYRWQGAAMLRATT
S-TGPADIPRTLDLDNVAVTR----------------------------EWLNRVWECD-
GFRNALELATPVLSDAIEAVVQGRQS------EPRHVRRTAVSTVSYLLRWQHRPTPLGL
FAGTAPVTVG-PRASARWR-DKHR---VLIRPDSE-WVTDMVLRLQRIPALLARLPLVAN
NAARTRGDRLVAPGPPSDG----HAVLLAPVEISVRNARPVAAVMDAARS--PIPYGALY
GHLRD-SFPQATPEQIDALLTSLVEQQFLITSLWAPMTTVDPLQHLCHELEQHDADNIPD
VR--------D----LVHELYALRDEVSAH---QPTLSDISVSALATRMRALTA------
------VTP----------TPLLIDTAL---DCET------------QLPQTVIAE-AQA
AVSALYRTTPQ----PYGYQHWRDYHRRFRARYGVGALVPVMDLV-ADNGLGL-PA-GYV
GSERGASLKVRTD------------------------------RDELLLSLMQQVLLDGR
DELRLTDD---MVHALEKAAGTDER----LFVPRVEAAFEIHAPSTRALSS-------GT
FDLLL--TAVPRPGSSMAGRFAHVLPPAHQNALATS-------YRGAPDR-LAAQLVFPP
RRHRNENVTRTSRLLPHIIE-LSGHL-------ERDE---TTIRLADIAVTADP--R--S
FHLVQL-STGRPIDVRVLHALEGG--TQTPPLARFLAEVA--N-GRYAAYKPFDFG-AGS
RLP---YLPRVRYR-RAILTQARWLLMAHD--LP-------ARKAPRQE-WEDAFTAWR-
-NRLRVPRQVAVIEYDQRLPLDLSHPVHLR-VLRAHLD--N--ARRVELREVPDA-----
DAHGWIG------RAHEIWLS-LGRSEP----------DTP-----YVPRLSSTTSPGTE
RHLPGG--GNVLHAQLHAHPRRYDEILSHHLPRLLAAFGEDPPT----WWFTRHREMARP
DAD--Q-HLGLTLLLP---P---DSCEVGARHVRAWADSLHTMG--LASGLALAPYQPQT
GRFGH-GPAMNAAHQVFAADSAAALAQIQLA----------ERTDAFAPQALAAASALHL
VTP-LAPNAAA-----AEEWLVGN--LPQGTGRLDRALRGQVLELTGP-----NGASALA
SLPGGR------QVAEAWRA----------------------RAAAV---DFYRTAL---
-----VSERHPLDVARSLLHQHHVRALG-VDPRTEETTIRLVRTAALQHRMADR------
--------------
>NZ_ADDL01000007.1|c1|175802-178864|-|ZP_06235527.1|Lantibiotic_dehydratase_domain_protein
----------------------------------------MATGAAELSWSPVGLLRITT
E-PGGLDLPESLDLSPTAPVG-------------------------PLLVWLTTTWKRA-
EIREALVSASPALCAQIETVLADSGA------APARVRRVAASLASYLLRWQRRQTPFGL
FAGVGPARFESAAAKVRCG-TGHR---YAVRADAG-WLGEVTARLGPCPELAARIPVVAC
NAIVRRGGRLVAPGTAPDA----GPPGEAALEVSVRATGPVVFALDAATA--PVPLDELR
ELLAS-RFPAASADQLDGVLRGLVGNRFLISALRVPISEPDALRAVCQVLQDVDAAAIAE
VA--------D----LVGELYAIRDALPAD---PVDTVPAGVSARMIAQAPAAR------
-------------------SPLLIDTVA---DCEA------------EIPPAVARE-IRD
AVTVLYRLSPH----PFGHPAWREYHNAFRARYGTGALVPVLDLV-ADSGLGL-PA-GFL
GSARETPPRQLSE------------------------------RDEKVMALVQEAMASG-
GELLVTDA---VIAGLCADSGAGPV-----LPPRTEVAFEIHAWTVAQLQA-------GR
FTLEV--TGTPRPASSMAARHAYLLPPEEFAAVRRTF------EPGEPGL-VAAQLSFAP
RRQRSENVTRNGRWSPKLIS-LAEHR-------RPGA---DVIDLSDLAVTADD--Q--G
FDLIQL-STGDRVAPLVPNALEAS--VHTPPLARFLAEVS--I-ATCAMYGSFSFG-AAS
RLP---YLPRVRYR-RTILSPARWLLDAAQ--LP-------GRRAAPAE-WEQALAGWR-
-AHWQVPDHVALVEHDRRQPVDLRHPAHRH-LLRSRLQ--S--ARRLELRETAPP-----
EQLGWIG------RAHELLLP-LTRVERDV--------VPV-----SRKRPSSRPVLAAA
LRLPAA--SSVVAARLYAHPERFDDILADHLPRLLRRLSGDPA-----WWFHRYRNLQDH
QGD--Q-YLALFVDVGE--P---GAYAAAAGQLADWAEELDRER--LAAQLTFASWQPPT
GRYGH-GAALDAALGAFRADSAAALAQIR------------AARTGTDPQALTALSFLDL
ASA-FAGDAAT-----GREWLLDT--VPQSHGPLDRALRCQVIAL-------AEGPGPLA
EMPAGR------AVTAAWQD----------------------RAAAL---TTYAREL---
-----VSQREPAGVLGPLLHLHHLRTVG-ADPDAERVTGRLARALALHAQAIHANG----
--------------
>NC_013929.1|c11|3631218-3634346|+|YP_003488857.1|putative_Lantibiotic_dehydratase
--------------------------------------MTAGAERLLYRLAGVPIVRATT
R-PDGAPLAEGLSLSGSPEAV--VAEG---------------------LAWLTQAWQHE-
EARRAVETASPALAQQISGLLEGRSV------PVRQVRRLVVSLASYQLRWQGRATPFGL
FAGVSTAEVG-TGAYVRWG-ESHR---TVARADAQ-WLGAVIAPLEQHPRLLERLTVITN
PVAFVRGDRLVVPGEPPDD----SPGVLAPIEISVGHTRPVRTATEAARE--PIRFQELL
TLLAA-EYPSAPPEQIRSLLAGLVAQHLLLTNLRASMTVPDALGHLRAQLEAADADELPD
LT--------S----LVHDLRLIHDDLSCH-NDTVASPTAAYAMRAAVAERMNA------
---ICDIAP----------QPLVVDTAL---DCDV------------SLPEAVIHE-AET
AASALLRLTPY----PFGYPRWKDFHVRFRQRYGVGAVVPVVELI-GDTGLGL-PA-GYL
GSPVANTARTLTE------------------------------RDETLLALVQQAVIDGA
EEIVLTEP---LVRQLAVGDPSEML-----PPARAELTFQIHATSPQAVEK-------GA
FRLLV--SSAPRPGSSMAGRFADLLPEADRKILADTYAAL---STDAPGA-IAAQLSFFP
RRRRSENVVRTPQLLPHTIS-LAEHR-------DPHP---DLIPLHDLAVTADA--R--Q
FHLVQL-STGRRVEPRVVHALEAG--TLTPPLARFLAEIT--T-ARCAVYKPFDWG-TAV
RLP---YLPRLRYG-RSVLSPARWLLTAAD--LP-------KPAATPAE-WDKALATWR-
-RRLRAPEAVVACESDLRLPLDLSQPLHRA-LLRNRLD--A--AREVELQEAPTP-----
ADLAWMG------RAHEFFLT-LRLAQPRAA-------ERN-----TVMSSPLPAVKRDA
GHLPGR--SEWLYAQVHGHPDRQDEVLTEHLPRLLDGWTGLRQ-----WWFRRHRDTTRP
DSE--Q-YLDLHLRLPT--P---GEYGQAAARVGEWAADLRGCG--LLAHLQLATYCPEA
GRYGH-SEAMDAAHEVFAADSAAALAQIT-----L------AIHTGLPPKAVTAAGLVDL
AAS-YAESPDI-----GMRWLIDR--LPHEQGKLDQKLRDTGMRLADP----ADDWATLR
ATPGAE------TVTRAWER----------------------RRTAL---TTYRTHL---
-----ARQRDPYSVLRSLLHMHHVRTIG-VDPDRERVTHRLARASALRQSAREHWRTP--
--------------
>NC_007777.1|c18|3927165-3930248|-|YP_482401.1|lantibiotic_dehydratase-like
---------------------------------------MAVRSPAMYQWAGAALLRAST
D-PGGLDLPADLDLFGADAAE----EG---------------------SAWLSAMWRRE-
EIRAAIAQASPALIQQVDTVLTSSGH------DVRVVRRTVLSVASYLLRWQRRPTPFGL
FAGVALARID-AGAKVRWG-RDHR---VEARVDAG-WLGDVLARLQRCPTLRERLSLVAN
GAGLVRGDRFGAPAPTPDG----IADELAPIEVSVRHSRPVCAALEATRK--PVTFSELR
TLLME-RFPSAPAQRIDEMLTGLLDQGILLSNLSAPMTCLDALGHACAQLEAVDAHSIPE
VS--------D----LVRSMFEIHKEVSAT--------SQVLGSRSAVTEQMHA------
------LSE--AA-----EVPMIVDTIL---ECDV------------HIPDQVAQE-ARN
AVQVLYRLSPY----PLGYPAWRDYHSRFRTRYGTGAFVPVMDLI-SDSGLGV-PA-DYL
GSARRRAARQVSE------------------------------RDEKLLALIQRATLSGG
GEIVLTDQ---MIEELAVSDPADVH-----LPARVEVAVEIRSMSVEALAR-------GR
FTVAV--TGTPRPGSSMAGRYAHLLPADGRDLIAGTF------AAAGTDA-IPAQLSFAP
RKRRNENVARTQQLLTHVIP-VAEYR-------DGDE---RLIPLTDLAVSVDD--R--R
FYLAQI-STGRYVEPRVAHALEAG--VHTPPLARFLAEIT--T-ARAAVYKAFHFG-AAA
QLP---YLPRVRYR-RTVLSPARWLLAAGE--LP-------GRGASTAE-WDAALEDWC-
-SRWWVPGHVAMVEHDRRQPVDLGHPLHRL-LLRTRLE--R--ADRLELRETSTL---ED
V--AWLG------RAHEVLIP-MVLDPQPA--------TDP-----GPGISTRRVVAVDA
GHLPGE--STVVSAHLYGHPARVEELLTQHLPHMIDAFGVH----RPRWWFRRNREMRRP
EID--Q-YLAVYLWLSE--P---SAYGPAAACLARWADDLRRQH--LLAHVSLTTYDPQS
GRYGH-SPALDHVQDVFAADSACAIAQIS-----A------SIRAGVHPQALAAASLVDL
AVS-YAGSPQD-----GLDWLIRE--LRQEHGRLDPALRQQTLELADP----HGSWTRLQ
SLPGGR------DVLAAWGT----------------------RASAL---AAYRDAL---
-----ADQRDPMPVLRSLLHLHHNRAVG-VDPAVERATGRLARACALRHTAHRTET----
--------------
>NC_003888.3|c21|7696262-7699360|-|NP_630996.1|hypothetical_protein
--------------------------------------MGSRKDCPLYRCADTALVRAAR
S--ARLPLPAWPDLTDDTPDC--EVRW---------------------QTWLRDVWSLS-
EAADSIEQASPLLAQQVQALCSVASP------ETRQLRRAVVSVMRYLLRMTGRATPNGL
FAGIAPASFG-ERPGWSWG-EWHR---PVIRADGD-WIADLVARLEADPELLRHLHVMAN
NTILIRGDRLIMPYPPRSC----RTDGSPAAEVSVRYTSAVRIAVDAAAS--PVPVHAVV
ALMRS-EFPDVPADRVEGLVSSLVERGVLISSLHAPSATLDALDHLVEQA---EAAAAPS
AT--------G----LVADLRTVRDAIARH--NQVLAPADGRRLRTALRRKMTA------
------LSS--VK-----AQPFTLDLRM---DCSL------------TLPPQVARE-AEQ
AATVLARLSAY----PFGTPAWKDFHNRFFERYGINSLVPVRDLVDPDVGLGF-PV-GYR
DAQPEQGEALTA-------------------------------REQRLLSLAQAAVLDGR
DEIHLDED---LIRTLTVGDRNAPH-----VPAHTELRFRIRATSQEALES-------GD
FVLHG--IAPSRGIGTTIGRSLGLLAPDEQARVAVMLEEL---PVNTPGA-VPTQVSFTP
LDRGDTNVTRVTELLPAVIS-LAEHR-------PVDA---RTIPLDDLAVGCDR--R--R
LYLVSL-SRACLLDPMTLHALDLR--GHTPPLGRFLTEIS--R-AQTAVLTVFPWA-SAT
ALP---YLPRVRYG-RAILSPARWRLDRSE--LP-------DRRASWGE-WHKAADEWR-
-ARRRVPDEVAVAEGDQLLPLDLSERAHLA-LLRAHLD--T--HESVILTEAESE-----
--EGWFDG-----RSHEIIAP-MTAVRPPQ--------WPA-----VPPVTADQLVTRDH
GYLPGA--ASWLLVKLYGHVDRQPEILADHLPALLGQWDEPPT-----WWYMRYR-----
DPR--W-HLRLRIAVPS--E---QDFALTARRVSSWANGLRRAG--LLADMQFATSYPET
GRWGP-GPLMNLAEDVFAADSRALAVQFA-------------QSSRPHQQVLAAANFVSV
AAA-FTGSTAA-----GMNWLIAH-GRITDPRPMDRTVRGQALRLADP----ADGWAALR
AAPGGD------AIASAWSE----------------------RDAAL---ARYRQKL---
---DAFGGIDLDLVLDSLLHAHHIRAAG-IDKDDERMCVRLAHAAAMAWTHRGDHHESA-
--------------
>NZ_ACEZ01000152.1|c1|1-2837|+|ZP_05533394.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------DVRRTALSVARYLLRSQHRATPFGL
FAGVTTAEFG-SQTRACWG-AEHV---AVGQASAE-WLAAVVERMESCPDLLEWLPLVVN
NTVTSRSDRLIVPFQSDA-----QDDRTRAVEASLALTEPVRAVLAATRA--PIPVAALA
DKLQA-EFPEAGPEKVRRLLVELIQRRVLITSLHAPSTETDALGYLLDQLDAIDADTLLP
VA--------E----MARELRAIRTGLNEC--TSRGGRDSVAARMRALVPGLRR------
-------------------HPVALDLRL---DAQL------------VLPDAVARE-IER
AALILTRVSAR----PYGTAAWGAYHQRFYERYGIGTMVPLQEVV-ADSGTGY-PD-GYP
GTPSGARRPRLSA------------------------------RDDALVRLAQAAALDGR
EEVVLTDE---LIDALDVGPDEPRV------PPHLEVGVRVHAASVGELQR-------GR
FRLEV--VSVSRGAGVSTGRFLSVLTSAGREPLTAELADL---PTADSNT-VPVQLSFPP
LLPESAHVTRAPQVLPTLIG-LQEHR-------APAD---DVLTPADLAVGCDG--R--R
MYLAAP-ERGQRIEAVGMHALNLH--THTPPLVRFLTELS--R-AQCAQVTVFDWG-AAA
AMP---FLPRLRYG-RTVLAPARWRLEATE--LP-------GRSHRRAE-WDTTLTDWR-
-ARRRLPRWVYLVEDDRRLFLDLDEAGHRT-LLRHYLD--R--VRVAVLVEAAEP-----
GALGWCDG-----RAHEVVVP-LKATRPPA--------WPT-----LPAPTPARALSTAQ
MQVPAA--SSVLLATLYGDARRQDTLLARHLPDLLERLGGPP------WWFIRFR-----
DPE--Q-HLRLRIALHT--P---EAFAETARTVSTWADELRGAG--LLADLRYPTSYREM
GRWGS-GTAWDAAEKVFRADSRAILAQL-------------SQPRRPHHRTLVAAHTVSI
ASA-FLGSTQA-----GMRWLIDR-IPPTAPASLPRPQFTDAVRLADP----GNDWAALR
GAPGGA------AIVSAWAD----------------------REAAL---AAYRRHL---
-PGPHTQGIALDDVLTSLMHVHFVRHIA-VNFPEEEVCLYLARAAALAWTARTTGRTP--
--------------
>NC_009921.1|c6|3311180-3314245|+|YP_001507128.1|lantibiotic_dehydratase_domain-containing
---------------------------------------MVDVEVPLYRHAGGAMLRAAV
L-PLSQQPEDWPTLSDPDSCR----------------------------SWLRAVWALP-
GFADAIRYASGSFAAQVEAVLDDQAA------GGKQVRRVTLAVVRYLLRSLGRPTPFGW
FAGVAGVRIG-DDVRARWG-SAHR---LVLRADTL-WLDDVVERLEMLPDLLAHLDVMAC
DLLVERGDRIEMP--------------RGPGRVTVRNTAVMRLVRNLAAK--PIPFHLLL
DQVAL-AFPAAPATAVRRVLGDLITQGILITGLRAPMTVADPLTHVIAVVEGAMIGDGEA
VA--------A----VLGDLRAAQQVIRTH-NDDHVEPGTQARLREEASERMRR------
------LSP--AG-----RTSLAGDLHL---DCDI------------AVPTDLADE-MAH
TVGALLRLTCQ----PRPDQGWNDWCREFWDRYGTGALVPVLDAVHPDTGIGW-PA-GFP
GSMLAEPEDTVSH------------------------------RDQELLRLAWDTVTAGH
HELVLTDT---LIATITADKPVDPR----WIPPHVELGARVHATSVQALAA-------GD
YTFGVHP---AWAFGTLTCRFGAAVGRAGLDTVFAAA------PSAVEGA-LPVQMSFPP
LFPHSENVSRVPRWLPQVLP-VGEHR-------ADES---TVIRLDDLGIVAVA--D--G
LHLVSI-SRRQVLEPQVFHALALR--KQAPPLARFLATLT--R-GFLARFTEFDWGPLAT
GLP---HTPRVRYR-RAILSPATWRINTAD---------HTALRADGHS-WEEAFARWR-
-QRGACPDIVELHDDHRSLRLDLTVDAHLA-ILREHLD--K--HGRATLTETDSV-----
EDTGWMGG-----HIHEIVLP-FVRAVPA---------APN-----LVTGALPLVTSANA
AHRPASPHGSWLYTQVFTHPERLDDILRTHLPRLLDLLDGDRS-----FWFARYR-----
SVRETD-HLRLRIRTAG--Q---EEYAAVACAVGQWGQQLCDAG--AASRLTLATYHPEI
GRYGS-GAAMDAAEAVFAADSHAVATALQ-----L------PTPLAVHPMALVAIGMVDI
ADG-FHSDPVH-----ANTWLLEH-LAAKATPGADRTVTEQV-----------TRWAARR
TLPGDTSLPA--ALVQTWQA----------------------RREAL---IRYRLAL---
-----PGNADADQVLSALLHMHHNRARL-IDRADEATCRRLARQIALTRRAHTTADSP--
--------------
>NZ_ACFA01000759.1|c1|48-2993|+|ZP_05542347.1|lantibiotic_dehydratase_domain-containing
---------------------------------------------------------MPA
VLPVGARPDDWPDVESLDDCR----------------------------QWLARVWADD-
SFVVPLQAASPRLVNFVEEILDGRTV------PQKRVRSATLSVAGYLLRATSRPTPFGL
FAGVAFAGVG--PVSANVG-TNHQ---ALARPDTL-WVDHVRRTLERRADVLPHVTIQVS
TLSFQRGDAI-------------GASRSGGRLASTPVTRPLAVLLSAAST--PTTGRHLL
DVLAT---AGGTPAQATRLIGQALDAGYLTSDLAAPMTVDDPLGHIVRTLRPHAGTLDPA
TV--------R----ILDHLEETRLALAVH---DQSGHEEVGELRDLADDRMRK------
------IQPADCR------SRISLDLRI---DAQM------------TVPHHLLDE-VER
AAHALARLTRA----QGESPVWAAYQTHFWERYGAGVLVPVRDAADLAAGIGL-PA-DYP
MSVWSEPPLTVLP------------------------------RDEQLAAWAMQAAMTGT
RELVLREQ---DVDDLAGSEPDRPT------APHVEIAFKIRAASKEAVSS-------GD
FTLDVRP---AWTAGVLSGRFTAVLGRRLSDLYRTL-------PTMTEGA-LPAQLSFMP
SFPHAQNVARIPALLPYVIP-VGETR-------TAAD---HLIGIDDLAVYSTG--R--D
LYLVSL-SRRRIVEPHVLHPLALE--KQAPPLARFLAQLG--R-GFATAWTAFDWGPVAS
ALP---YLPRVRHR-RAVLAPARWKLPATD--LP--------TGPFGPA-WHKALGEWA-
-ATWQCPARLQLLDDDRTMPLNPAESLHAR-LIHQHLR--R--HSHAVFTEAVSD---EE
L--GWLG------HAHELTIP-LATTHA----------PAP-----HPDLTHAPVVTNQD
LDHPGDAEQRWTQAKVFTHPTAMDQIVTARLPRLLDVLGTSQ------VWFVRYR-----
SLQETD-HLRIRVATGV--P---DSHEATVRALSAWTKQLTADR--LASQLVLDGYRPET
GRYGT-GAAMDKAEDVFVADSLVTRYALT-------------DVPTLEREAVCALSMIDI
AEG-VLGTHEG-----R-AWMAETPVRGIGRLEVTRQTVDQV-----------KTGPLVH
TTP---------RLARAIAQ----------------------RRTAL---EAYRAQT---
------DESRLGEALQSLLHMHHNRLIG-PDRDSEAAARHAARQACRSLVLRGTT-----
--------------
>NZ_DS570387.1|c1|57540-60668|+|ZP_04997226.1|conserved_hypothetical_protein
-----------------------------------------MTSVNYFQATEPILLRISS
LTPDGLRSSPPRSGDGELPDSEQL------------------------ISYIQEMMKDD-
FFREAVAVSSVSLASALAKVERRAVM------SRKNLLSTAVSLTRYFLRITGRPTPFGL
HAGVAEVRTGDRARAVFTGTAR-----KAVRLDAG-WLAGAADSWLALPAVRRAVDVVAN
DLCTVRGDRLVLPYVTASPV---DGTPATGRELSLRHTTLTAWIRDRART--TLRYGDLL
ADAVK-VFPTAGEERLDGVLLSLVRSEVLLTSLSPRLIDEKFLARTMSVL--------GP
SS--------D----EAAGLRDVLSALVDY---RSAPPGDGAGAWTALEDAGRA------
------VHP--DG-----RSVAQVDLRS---PAEV------------ELPRAVLAE-AEA
YAGALWRIAPE----GKSHRRMRAYYEAFVEKYGEGAAVRLPDLIDPHRGLGY-PG-GYL
NPRVSNDPRLYVHERALEGERPGD-------------------RLERIAALIQRGVVNPD
RELVLSDE---DIARITIDSRPSAL------PHSLDLCFQLLADSAEGIDA-------GD
FRLLASPMVGAGLAGATAARFAYVSRTEEAVARLVD-------PAGADDA-ITAQVVFRP
QIPRLLNVVQVPELTRYDIP-VGAFP-------AGNGN--RHIDWRTLFVESDG--E--R
LRLLLP-DSGREVRPVVPHMLSMS--SVAPNLARFLGELR--FTGERKVWQPWDWA-GYG
LSP---WQPRVRIG-KVVASPLTWRPSPEM-----------RHLTNQRDDWSRAVDHWR-
-REVRVDDEVTVVSGDKAYGIDLRDAFHRE-VLRRDLA-----REDLVLTETPRA---LG
FGHGWSAG-----RSNEICIPLVAHPPRP---------PRA-----PHVPVAAKTICVPE
RHPVG---SLWTSIHIHAVLEAHDALV-RGLGDLTAQVTDTVDR----WFYLRYF-----
SPE--P-HVRLRLRSPD--A---ASAAVVRQIVLEHLHRARETG--LLREFSAQAYEPET
TRYGG-PRALDAAEEVFCRDSRTAVAQLTLLG---------SGRSPVPLHLMMCAGHAML
LES-LGDWDWR-------GWAARQ-FPKCTDGSVTRGDVEAAARLIQP----GRTAANLA
AACGIP------GIETLWRE----------------------P-------SGLGRELGLS
GDAGHRADRRRDTALVSLLHMQHNRLIG-NDLASESRAIVLLGHVARQQLGRALNGKTQS
--------------
>NZ_ACFA01000003.1|c1|109624-112752|-|ZP_05536743.1|hypothetical_protein
------------------------------------------MRDDHYTAQDFLFVRVTA
LPRTGPGGGADGSPLGASAER------------------------------VREAAADP-
LFREALNVASGSLAASLDKLDAGVDL------GTKRLRRTALALSRYALRAGTRPTPFGL
FAGVAPARVAAATKVDIAGPGS-----KTVRLDAA-WLTERVAAWLERPEVRHGVDVVLN
DLCRKRGDRLVL--------------TGKGKETSVRATPLVAWVCARTEH--PVRYAELL
EQACA-GFPRYASAQVDTVLSQLVRAGLLVTSITPQDLDEALYDRLASAL-------IPV
PE-------------AWSELERIRAALDAY---AAARPGQGHAAWRELMRLADP------
-------QSTATR------PPVHVDLRM---QADV------------HLPRTVTDE-AAR
YASAMWEISGT----WQTHAHMRRYQNRFLEAYGTTGIVPLGRLVDPHRGIGL-PP-GYG
PSAEYTGDGPMPGQEADPLPKE---------------------RRALTHDLVQEALLGGE
DEVRLSPR---VIDLLATAGRTDET--TVPPPRSLELCFSLLAESGQALDR-------GD
FRLLSPPYLGSWTAGATAGRFAGLLGMESELTSLL--------AGLGDERTVPAQVVYRP
HTVRGLNMAQVPRLLPHRIP-VGVYA-------DRSEP--GTLDWRQLLVTPGP--F--G
LRLVLP-EDGRDVLPVVPHMLALD--REAPPVARLLVELA--Y-GRARTWTGWNWC-GLE
GLP---YLPRVTYG-RVTLSPRRWIPDRHL-----------REAMEDPSGWDETVKAWR-
-ERYRVPDEVNLARWDRMYRVDLRDPWHRE-VFRQEIR--G--GGSLAIMEDLTD---GG
RRLGWSAG-----HSAEVVVP-LTRPSPAERYEDENR-PRP-----GSRMPAPRPTNHST
RHLPG---EDWLYAKFYADEDTQDELLRAAIPTLVRGTGTHLRH----WHYLRYR-----
DPE--P-HVRLRLHGAA--E---DLRALVLPRLAELSRAWEEAG--LIRGMVIDTYRPET
DRYGG-PDALPHAERMFCLDSQSALTQLRMRT---------RGALTVPAPVLAAVNHALL
LES-LGDWNWT-------AWIGEV-LPKGPAHAAFRKFEDQATALIVPGRTAHSAAPALG
E-----------ALTSAWTT----------------------TPET----RAYGALL-LS
DEGRAPGSEQHAEAVLSLLHMQHNRLLG-IDRVGEDTGYAVLRGVARAHQGRLAHAQADD
QAEEESR-------
>NZ_GG657756.1|c10|8086352-8089513|-|ZP_06533438.1|conserved_hypothetical_protein
----------------------------------------MAAESEAQRAAAVFEVREPV
LVRMASRPRGAAPATVDAAEP---------------------------VSGARQLAADP-
LLGQAVRVASGSLAHSLARLTTDEGASAL---GRKRTLSAARTLTRYARRAGARPTPFGL
FAGVGAARFG---SVAKAGPGTGE---VAVRLDGA-WLRRRVLAWLEEPSVRRRVDVVLN
DLCFVRDGRLYL--------------RTGAQEQSVRDNALVGAVRERARN--PVPYADLL
VSLAE-RFPALDAERLDGQLAGLLQHGFLLTSITPHRIDVALLDGIEAVL----DGALPD
DA---------------RALRDVRAACARH---QQDPPGMGGDSWQDALDAVRR------
------LDVPGTGDDAHARPPLHVDLHV---PGEF------------VVPEAVGRE-VCR
YAAAIWAITPQ----WTTLAYMRDYRERFIERYGTACAVPLGELVDPHRGLGL-PS-EYG
AEPVYARGGPGDEADGP--------------------------RRAMIGELLQEAVLSG-
GDLVLTDE---VVGRLGEVAGHDPA---AAPPRSLELCFQVLSESTAALDR-------GE
FRLLGSPHIGAWTAGATAGRFAAAAGLTDELARLAA-------ESTDDTV-ITAQVELMP
HEPRGLNIVQVPRLLPYRIP-VGVPD-------DRRDP--RCLDWRSLLVAAGS--D--G
LRLLDP-RSGRPVRPVLPHMLALD--TQAPPVARFLMDLA--T-ARPRVWSGWNWA-GHD
ALP---YLPRVRYG-RVVAVPGRWLPGRRL---------RDAARAQGAGAWEQGLDAWR-
-RRLAVPDRLQIARNDQMYPVDLRERWDRD-LLRAELT---AAQPRFVLYEDLTA---DG
AGLGWNGG-----HSTEIVVP-LAAARRATGRTAPRRAEPARGRTVPPVRPVPVRPAPVR
IHLPG---EDWLFVKWYAEPSAHDALLTEHLPALLSEVEDEVDR----WFFLRYL-----
DPE--P-HLRLRFHGDP--G---ALNGRVLPAISRVTRALVESG--ALRTMALDTYRPES
DRYGG-EAVQEAAERFFRTDSLSALVQLRALR---------GPARALPGAVLAGLGHAVL
LES-LGDWDWC-------GWVDRM-FTKTVEHEVYQRHRAVADRLIGP----GRAVSSAA
AALGAP------SLGALWSE----------------------SPEP----RAYGELI---
---LSAPEADRDEALLSLLHMRHNRLFG-IDRAAEARGYAVLRGAVRTHAGRRRHESGSG
IGSGR---------
>NC_003888.3|c3|256526-259687|+|NP_624599.1|hypothetical_protein
----------------------------------------MAAESEAHRAAAVFEVREPV
LVRMASRPRGAAPATVDAAEP---------------------------VSGARQLAADP-
LLGQAVRVASGSLAHSLARLTTDEGASAL---GRKRTLSAARTLTRYARRAGARPTPFGL
FAGVGTARFG---SVAKAGPGTGE---VAVRLDGA-WLRRRVLAWLEEPSVRRRVDVVLN
DLCFVRDGRLYL--------------RTGAQEQSVRDNALVGAVRERARN--PVPYADLL
VSLAE-RFPALDAERLDGQLAGLLQHGFLLTSITPHRIDVALLDGIEAVL----DGALPD
DA---------------RALRDVRAACARH---QQDPPGMGGDSWQDALDAVRR------
------LDVPGTGDDAHARPPLHVDLHV---PGEF------------VVPEAVGRE-VCR
YAAAIWAITPQ----WTTLAYMRDYRERFIERYGTACAVPLGELVDPHRGLGL-PS-EYG
AEPVYARGGPGDEADGP--------------------------RRAMIGELLQEAVLSG-
GDLVLTDE---VVGRLGEVAGHDPA---AAPPRSLELCFQVLSESTAALDR-------GE
FRLLGSPHIGAWTAGATAGRFAAAAGLTDELARLAA-------ESTDDTV-ITAQVELMP
HEPRGLNIVQVPRLLPYRIP-VGVPD-------DRRDP--RCLDWRSLLVAAGS--D--G
LRLLDP-RSGRPVRPVLPHMLALD--TQAPPVARFLMDLA--T-ARPRVWSGWNWA-GHD
ALP---YLPRVRYG-RVVAVPGRWLPGRRL---------RDAARAQGAGAWEQGLDAWR-
-RRLSVPDRLQIARNDQMYPVDLRERWDRD-LLRAELT---AAQPRFVLYEDLTA---DG
AGLGWNGG-----HSTEIVVP-LAAARRAAGRTAPGRAEPARGRTIPPVRPVPVRPAPVR
IHLPG---EDWLFVKWYAEPSAHDALLTEHLPALLSEVEDEVDR----WFFLRYQ-----
DPE--P-HLRLRFHGEP--G---ALNGRVLPAISRVTRVLVESG--ALRTMALDTYRPES
DRYGG-EAVQEAAERFFRTDSLSALVQLRALR---------GPARALPGAVLAGLGHAVL
LES-LGDWDWC-------GWVDRM-FTKTVEHEVYQRHRAVADRLIGP----GRAVSSAA
AALGAP------SLGALWSE----------------------SPEP----RAYGELI---
---LSAPEADRDEALLSLLHMRHNRLFG-IDRAAEARGYAVLRGAVRTHAGRRRHESGSG
IGSGR---------
>NZ_ACFA01000915.1|c1|40687-43767|-|ZP_05543598.1|hypothetical_protein
-----------------------------------------------------MLVRMAS
R-----PRDAALARVDAAEPV----------------------------SGARQLASDP-
LLGQAVRVASGSLAHSLTGLTSDEGAAAL---GRKRTLSAARTLTRYARRAGARPTPFGL
FAGVGTARFG-SAAKAQPG-TGE----VAVRLDGA-WLRRRVLAWLAEPSVRRRVDVVLN
DLCFLRGGRLYL--------------RTGGQEQSVRDNALVSVVRERART--LVPYADLL
ASLTE-RFPALDAERLDRQLAGLLQHGFLLTSITPHRIDVALLDGIEAVL----------
--------DAA----LPEDAQALRDIRAACARHQEDPPGLGGDSWQRLLDEVRR------
----LDVPG--THSDTHARPPLHVDLHI---PGEF------------VVPEAVGRE-VCR
YAAAIWAITPE----WTTLAYMRDYRDRFIEHYGTACAVPLGELVDPHRGLGL-PP-EYG
TQPAYARSGPGDEADGP--------------------------RRAMIGELLQEAVLSG-
GDLVLSDD---VVRRLSEVARHDPA---AVPPRSLELCFQVLSESTAALER-------GD
FRLLGSPHIGAWTAGATAGRFAAVAGLTGALARLAADTA----GTPDDTV-IPAQVELMP
REPRGLNIVQVPRLLPYRIP-VGVPD-------DRDDP--RCLDWRSLLVAAGS--D--G
LRLLHP-DSGRPVRPVLPHMLALD--TQAPPVARFLMDLA--T-ARPRVWSGWDWA-GHD
VLP---YLPRVRYG-RVVAMPKRWLPGRRL--------RDAARAQGAEA-WEQGLDAWR-
-RRLAVPDRLQIARNDQMYPVDLRDRWDRD-LLRAELT---APHPRFVLHEDLTA---DG
AGLGWNGG-----HSTEIVVP-LAGTRRPAGRTAPE--DAE-----RAHTAPSVRPAPTG
IHLPG---EDWLFVKWYAEPSAHEALLAEHLPAVLAEIEDEVDR----WFFLRYQ-----
DPD--P-HLRLRFHGDP--E---VLYGRVLPAVSRVSRALVESG--ALRTMTLDTYRPES
DRYGG-EALQEAAERLFRTDSLSVLVQLRAP---R------GVARALPADVLAALGHAVL
LES-LGDWDWC-------GWVDRM-FTKTAEHEVYQRHRAVADRLIRP----GSAVSSAA
EALGAP------SLSALWSE----------------------SPEP----RAYGRLI---
---LSAPEADRDEALLSLLHMRHNRQFG-IDRSAEARGYAVLRGAVRTHVGRRRHESRGG
R-------------
>AM238664.1|c2|357598-360735|+|CAJ88053.1|putative_dehydratase
----------------------------------MAAESEAQQATSAFEVREPVLVRMAS
R-----PRGAALATVDAAEPV----------------------------SGARQLASDP-
LLGQAVRVASGSLARSLAGLASDEGATAL---GRKRTLSAARTLTRYARRAGARPTPFGL
FAGVGTARFG-SAAKAEPG-TGE----VAVRLDGA-WLRRRVLAWLAEPSVRRRVDVVIN
DLCFLRDGRLYL--------------RTGGQEQSVRDNALVGAVRERART--PVPYAELL
VTLTE-RFPTLDAERLDRQLAGLVQHGFLLTSITPHRIDAELLDGIEAVL----------
--------EAA----LPNDAQALRDVRAACARHQEDPPGLGGDSWQQLLDEVRR------
----LDVPG--TDGDAHARPPLHVDLHI---PGEF------------VVPEAVGQE-VCR
YAAAIWAITPE----WTTLAYMRDYRERFIERYGTACAVPLGELVDPHRGLGL-PP-EYG
AEPVYARNGPGDEADGP--------------------------RRAMIGELLQEAVLSG-
GDLVLTDD---IVGRLAEVAGHDPA---AAPPRSLELCFQVLAESTAALDR-------GD
FRLLGSPHIGAWTAGATAGRFAAAAGLTGELARLAADTA----VDPDDAV-IAAQVELMP
HEPRGLNIVQVPRLLPYRIP-VGIAD-------DRDDP--CCLDWRSLVVAAGS--D--G
LRLLCP-ESGRPVRPVLPHMLALD--TQAPPVARFLMDLA--A-ARPRMWSGWDWA-GHD
ALP---YLPRIRYG-RVVAMPGRWLPGRRL--------RDAARAQGAEV-WEQGLDAWR-
-RRLAVPDRLQIARNDQMYPVDLRESWDRS-LLRAELT---AAHPQFVLYEDLTA---DG
AGLGWNGG-----HSTEIVVP-LAGARRPAGRTAPE--DTA-----RARTALPVRPAPAR
IHLPG---EDWLFVKWYAEPSAHDALLVDHLPAVLAEVEDE----VDRWFFLRYQ-----
DPE--P-HLRLRFHGDP--A---ALNGRVLPVVSRVSRALVERG--ALRTMTLDTYRPES
DRYGG-EALQEAAERFFRTDSLSALVQLRAL---R------GVARALPAAVLAGLGHAVL
LES-LGDWDWC-------GWVDRM-FTKTPEHEVYQRHRAVADRLIRP----GNAVSSAA
EALGAP------SLGALWSE----------------------SPEP----RAYGQLL---
---LSAPEADRDEALLSLLHMRHNRLFG-IDRAAETRGYAVLRGAVRTHAGRLRHEGGSG
R-------------
>AJ862840.1|c1|50889-54206|-|CAH94359.1|putative_lantibiotic_biosynthesis_protein
--------------------MAGPAPRSRSETLPEDTMTTPVAAGALYAPVGMALMRSPV
LPVDDPALRALLPDDAPGPAPGTVGDGTADGSGTAGATDRAAGEADRLRRAILQLAAEP-
LVAEALALASPSLADRVDGLLDGRPA------TLPQLRRCFRSVLRYRIRMGGRSTPFGL
MAGVTPVRFT-DTLSLRFA-AAHR---KAVQPDAA-WVAEVTSRWERRPAILAHLRLSAN
GLCVRRGERLVLPYAAAETG---TADGRPGDEVSVRCTEAVRAALAFART--PVTHAELT
ARMRD-SLPEPPAGAVEGVIAELVAHSFLLTDLPPAPDAPDPLRHLTDRL-----ATVPA
AA--------E----ETARLREVAADLADW---GARPPGQGLTELRRAVRRMRG------
------LQP--CE------RPVTADLAL---DADV------------ELPRAVEQE-AAR
AADLLWRTGPP----VRWRRPLSAYHEAFLHRYGTERAVPLDELLDPVDGLGH-PP-PFA
PRTGGGADDGR--------------------------------RERVLLALAEEAVLSGR
HEIDLSDR---DIAALEDDAGVPP--------PSAEAVFHLLAPSPDALER-------GD
FTLVMAPLTGSWPAGALWGRFAPLLPGAAQGLGDLAATALTGGSDGAPDTPLPVQLVFRP
GDARCGNVIRTPRWTGHTLA-AGTFG-------ERSAP--GALGLEDLAVIAAR--D--R
LRLVSPVHGGREVAAGTFHMLNTG--THAPAHVRLLQLLT--A-DGVRPLYGWDWG-AAR
DWP---YLPGVRHG-QTVLTRARWLVRDPD---------VLDSTADTPR-WLPALRAWQ-
-RRWRVPDRVEAGTFDQRLPLDLTRPADLA-LLRQELR--H--RPDTEIHASIDP---DG
SGSGWLTGPTGGRHTAEICVPLLRRTAPAG--------ASG-----PTRPRATASNGRPP
RHLPG---GDWVFAKLYCPGWAQNTVLVHHLPTLLDGLADDVDR----WFFVRYA-----
DPD--P-HLRLRLHGGS--R---TLTARVLPRLHDLAEELRRRG--LAGRLVLDTYEPET
ARYGGTADAMAAAERVFHADSAAALEHLRLLDAPSAPHGPAGASAPPDPLLLAAAGQAHL
AFH-FPVPDDTSAERARARLLLSI-APRGEHHSTFRAHRREALRIVDP----FDGFAALR
ALPETA------PLMKAWDA----------------------TAASL---RSYGHHL---
----SGTDAQAVPLLASLLHLHHNRVSAGLSRSAESAVYATARGAVEAHLARHAATTTV-
--------------
>NZ_ADDL01000089.1|c1|14980-17784|-|ZP_06240729.1|Lantibiotic_dehydratase_domain_protein
------------------------------------------------------------
--------------------------------------------------------MDP-
VLAEGITLTSRTAVPSVLGACGDG--------------RLAATVRAFDRRARLRPTPRAV
FAGVQTVVVAERGCALRLG-GDHR---SRSAPSPV-SLTVLAEKLLDAPGVVERLTLTTN
NLVRRRGQRFERERP--------ALGSGAPELVSIRATAATTLVLRSCEQ--GAGYDAIR
AAVID-RWPAVPEAVMRGMVVEMTRQGFLLTDLLPDDLGDDPIRHLLGRL--------PD
GC--------D----VDGPLAGLRDQLRAA---DELPLGSARRLAALTSARESS------
----AHVCG--QD------NPLCVDVAA---DAAI------------TVPRRLLQD-AAE
AVSVLWTMSCA-------MPTLAAYHAHFVERWGHGRFVPFLEVVDPVLGLG--DE-GIE
TSIQSAQASPE--------------------------------RLAVLAAVLGDATVRGQ
AEVVLDEA---TIAALGAPGAEPPP-------PGAEAYARVLASSEQDLAA-------GR
LHLALY-VGGTQDAGSSAGRFTSLLPGSQPRV-----------PDPPAGA-LVAEVVVRP
RIPVLATVAPPTGVAQLRIP-VGVPT-------RH-----GDLRLDDLLVVADT--D--R
LTLWSQ-ERGCQVVPVLNSRIGPR--Y-LPAEARLLALLG--R-SGSRPWCLFSWG-SLR
DTA---FQPRVRYR-STIVAPARWRLPRLL----------TDAASEPSV-WAAQLTSWRL
STVPPLPNVVVTDDGERQLPLDLDDPRDAE-LLRRYVR-----RGLRAVTEQPGG---DG
TIQDVVTGP-SGRHLLELVIP-LAATKPL---------PAP-----PRPISALPRPAGAG
LHLPG---GPWLSLTIGAPTDQHDEILTG-LAALLPGLRGL----FDRWFWLRYR-----
SPAIGP-HLRVRFHGAP--A---ILGGQLLPAVSEWGARLVADA--LARGFSVEPYDQEI
ERYGG-PSTIEAAEEVFAVDSDLVLAAL------A------ATDEPDQRLVVAALTAATV
ARTVADGDPAA-----LGRPRLDR-ASHRRLAELRRLVTDAV----------RDGTIALP
------------LSHPAWER----------------------QSDAL---RAYHDRL---
------AAGRRADCASSVIHMHANRLLG--DTAQERIARALAAGLLARETASR-------
--------------
>NC_013947.1|c5|3827197-3830091|+|YP_003512355.1|Lantibiotic_dehydratase_domain-containing
-------------------------------------MLMDNSKRGGAAGTGPFRLADPR
F-----GLARLALLPDNDPGP--------------------------------ATPTDP-
VVVEGMFLSSEVDADT----------------APDHADRRLATQRAFDIRARRRTTPQSV
FAAVADVEFTDASPDLAIG-TAHR---VRTYPNPV-WLHQVCDQVLDSTEVLRGLRFTAN
NLTARRGDRLEADLPS-------NDSLTKPQHASIRATEAVDVIMDACRA--SATWSRIA
TAIRH-RWPHVPESVIDTALRQLVRSGIVVTDLTPPDACTDPISHVLDKL--------PD
TE--------P----LAKTLTRLRETLATA---DAHPPGDAARMTALKTAHRIT------
----DRLNK--TW------RPLCADTAA---EARI------------RLPKEAADQ-IAQ
AAGVLWRIAPH-------TDPLSTWHERFLHRYGAGRLVPVLEACDLVTGLGHDPN----
EPAAPHYRA----------------------------------STDALARLLNDALTCGA
LEVQLDAS---VIDALDQRRPGDQA------EPSAEIYTRIVVASSTASD--------GD
FCFAV--TNTASPAGSTRARFTGLVPDGPVV------------TDTGQDT-MVTELAFRP
LSFAVAALTGRAEPAPWRIP-IGTVP-------RP-----GDLLPDDLAVISNG--Q--R
LGLWSI-RHHRPVKAVHHNQLGH---HLMPPLAGFLCRLS--Q-HGTVAVRPWTWG-PFE
SAA---FTPRVRFG-NVILAPARWRLPEDL-----------RQAAKGRTPWDAALKRWRT
STRPALPITVVVEDTDRHLPLDLDRDDDRE-LFRRYVS-----RGVAAVTEPPGG----P
QAIQAVVPGAAGRHALEIVVP-LAAIAQP---------EPV-----TPLYSASVRCPCDG
AFLPG---GPWLSLAIDAPPSTQDAVLAR-ITHAATDVADLWKR----WFWLRYD-----
TPQRGP-HLRIRFHGDP--A---TLGGQLLPILGQTCAALTTEG--LSSGFGIETYHQET
ERYGG-PGAIELVEDVFHHDAHLTARLLS------------SHPSANDRLAVAAVSAAEI
ARIVADGDRAA-----LTPYRLDR-AARHVQGRLRP--RARAFDDTTP------------
------------LHPPLWED----------------------RAAAL---KIYRAFL---
------PPQRRVNCASSLIHMHANRLLG------DNNRERIARALAADLIARTTP-----
--------------
>NC_013947.1|c10|5748756-5751662|+|YP_003514142.1|Lantibiotic_dehydratase_domain-containing
--------------------------------------MLGQLLMTSHSTRRGTAFTTPF
RVADPRSGLARLPLLHNDPSP--------------------------------NTSIDP-
VVAEGMFLCSEIHADV----------------SPDSAEQRRATERAFDIRARRRTTPQGV
FAGVTELDINVAASTLSVR-TEHK---VRSYPNPV-WVHEIGDRVLDSAAVLHALTYTTN
NLAARRGDRLDVQRPS-------SDPRTGPQRMSVRRTEAVEVVLDVARS--GASWKQIT
TALTQ-RWPSIQDTTVEVVMRQLTRSGFLLTDLDPVDTCTDPLGHLLAKL--------PA
SE--------P----VREPLSWLRAALAEA---DAHPPGHPARMAALKTARNIA------
----DDLFA--TW------RPICTDTAM---NAHI------------SIPARVAEE-AAQ
AANVLWRMPPR-------HDPLAEWHERFLHRYGTGRLVPLLEVCDPVTGLGCDPG-NTE
VVPPPE-------------------------------------STEALARLINVALTSNK
MEVQLDAA---TITALDQRRPSDAC------EPSAELYATVVARDEHDRDA-------GK
FVLAV--TNMASPAGSTRARFAGLLPDASVA------------SDPGHGT-MTAELAFRP
TSHTVAALTGRADNAPWRIP-IGTIP-------QS-----GDLALDDLAVVSDG--A--R
LRLWST-QNNRPVRPVHHNQVGH---HLMPPVAAFLCLLG--Q-HGNTGLSPWTWG-PFE
RAP---FTPRVRFR-DVILSPARWRLPEEV-----------RDAATDRSTWATALRRWRT
SARPAPPATVVIDTSDRKLPLDLDRGDDRE-LLRRYVN-----RDVTAVTEPPGG----P
DAVQAVALGERGHHVLEIVVP-VSASHT----------EET-----APPAPALARQSRHS
VFTPG---SEWLSLAIDAPPSTQDAVLAR-LADAAHHATGLWHR----WFWIRYH-----
TPARGP-HLRVRFRGDP--R---PLGGQLLPLLGDTCANLTTDG--LSGGFGIEEYRQEI
ERYGG-EHAIEYVEDTFHHDANLVAHLLA------------ESSDPDERLALTAASAAEI
VRIVADGNRAA-----LVPHRLER-ADRRTHARVRPRARS--IDDGTP------------
------------AHRPLWYE----------------------RTAAL---TAYRAVL---
------PPDRRIDCASSLIHMHANRLLG------DNHRERIARALAVDLIAREAP-----
--------------
>NZ_AAWS01000009.1|c1|201960-205235|-|ZP_01689156.1|lantibiotic_dehydratase,_C_terminus_family
--------------------------------------------MNTFEPGNFYVLRTPL
L-----ERSYLKPPVGVAQGI---EQV---------------------RQHLQAMYALP-
ALQQALYIASPNLFAQLDRWHTLVALPAPNKKQSKDLQNLEQKLWMFLARAAYRCTPFGT
FAAVTAGEFRLQRHSSLAL-DGLGPMRTSSRLDMV-YLLRLRAALEADTEVREQLLYFPN
NTLYCNGDDMLCSFF--------DEQTLQHVASSKEFNEVAWELFATCRQAGGMRIQEMI
AHLMT--DPDLTEADCYEFVEYLINHHLLISELYPSLNGAEYLEQLHTRV-----KQIPA
AQ--------E----YLDIIEHIRRQLALI--DATPDPAQSLGLYQQLAGYLSAQPFYQA
QETAITAHP--NEKTASKKELIQVDAFR---DENGQ-----------ALSKTVPRHLVRQ
IATLIDNVGEV----PTTKADLTSFAQAFFKRYE-NEAVPLLLAMDEVTGVGY-PC-GKR
VAALPTYLQELGVVIGEGGAMPQVA---------DPKTGQTSALDSLLEQKYVEALQKGL
TEIRLSKV---EIQGLKASKPKAKEKQAPPLPPAMMAMGKLLYQTPDDLEHNPKQGNPRN
FRFQLYHASGPV-VGNLLGRFCYGSPLLKEKLSATLAQV----EPDNDHL-VYAEVDHLP
GQ-RVGNVIIRPRLRDYSIA-LGGAN-------TNDA---HQIPVTDLWLSTQEGGK--R
LVLHSR-RLGKQVVPRMSNAHNYA--HNAHPLYKFLCDLQ--YQEEYRQLPPFFKVQRWQ
QRS---YLPRLVYDDNLILSPRQWRVSRQL--LEAVQLQKKEDLHTTISTWTYKIERLR-
-QQLRLPQTVLLVEADNKLYIDFANPLSVGVFLQKVFV-----GKEVVLEEVIEE-----
---HVPSQS----YSNELIFP-ITNTVPPIH-------KQT-----QGLAAQTLPQSIQK
NFALG---SEWVYFKIYLGALGSDRLIVEDLYPLSKELKDSEHIDQ--WFFIRYT-----
DPDYGP-HLRWRLHLCHH-P---KELGEVVQVFSQKLLALKQQG--KIIHYVPDTYQREL
NRYL--PYNIALSEKWFALDSDFVGHILELLAQ-D------ETATDALKSALAIKRIKAL
LDA-FDLPKET-----REKIIHQGRVNFSREFGFDTHPQAQR----------LKKALAKH
TLPPWLPP----AYRLLFDQ----------------------LTEQE---VPLAQQIKAN
LQQHGANEAQLCSLLSSYIHMFNNRLFV-GGQRLEEM-----------WGYWKLEG----
--------------
>NZ_AAWS01000084.1|c1|6342-9611|-|ZP_01694962.1|lantibiotic_dehydratase,_C_terminus_family
--------------------------------------------MNTFEPGDFYVLRTPL
L-----ERSYLEPPVGVAQGT---GQV---------------------RQHLQAAYRLP-
ALQQALYIASPDLFAQLDRWHTLAALPVPNKKQRKDLQQLSQKLWMFLARAAYRCTPFGT
FAAVTVGEFRLQRHSNLAL-DGLGPMRTSSRLDMV-YLLRLRAALEADTEVREQLRYFPN
NTLYRNGDDMLCSFF--------DEQTLQHVASSKEYHEVAWELFTTCRQAGGMHRHEMI
AHLMT--GPELTEADCREFVEYLINHHLLISELYPSLNGEEYLEQLHASI-----AQMPA
AQ--------G----YLAIINHIRRQLALI--DATPDPAQSLGLYQQLAGYLSE--QPFA
QQTKEETDDGSNENKTSKKELIQVNAFR---DENGQ-----------ALSKTVPRHLVRQ
IATLIDTVGEV----PTTKADLSTFAQAFFKRYE-NEAVPLLLAMDEVTGVGY-PY-GKR
VATLPTYLQELGVVVGEGGTMPQVA---------DPKAGQTSALDALLEQKYVEALQTGA
PAIHLSKG---EVQSLKASQLPTKEKPRSLP-PAMVAMGKLLYQAPDDLEHNPKQDNPRN
FRFQLYQASGPV-VGNLLGRFCYGSPLLQQQLSATIAQV----EPDNDHL-VYAEVDHLP
GQ-RVGNVIIRPRLRAYSIA-LGGAN-------TNDV---HQIPVTDLCLSMPD--G-KR
LVLHSR-RLGKQVVPRMSNAHNYA--HNAHPLYKFLCDLQ--YQQEYRQLPPFFRAQRWQ
QRS---YLPRLVYDDSLILSPRQWRVSRQL--LEAVQLEKKEDLYTTISIWTHKIERLK-
-QQLRLPHQVLLVESDNKLYIDFTNPLSLGVFLQKVFA-----SKEVVLEEVIEE-----
---HVPSQS----YSNEMIFP-ITSTAPPSR-------KQA-----PALAAQTLPQSIQK
NFAFG---SEWVYFKVYLGTLGSDRLIAEDLHPLSKDLRDSGHIDQ--WFFIRYT-----
DPEAYGPHLRWRLHINHY-P---EEFGEIVQAFSQKLMALKQQG--KIIHYLPDTYQREL
SRYL--PYNMELSEKWFALDSEFVGHTLELLTQ-D------ETATDALKSALAIKRLKAL
LDA-FDLPKET-----REKIIHQGRANFSREFGFDAHPQAQL----------LKKALAKH
TLPEDF------NMQHQWAF--------------------IQLTDQE---KPLAQQIKAN
LQQHGASEAQLRSLLGSYIHMFNNRFFA-SGQRLEEM-----------WEYWRLE-----
--------------
>NZ_AAWS01000016.1|c1|82209-85472|-|ZP_01690534.1|lantibiotic_dehydratase,_C_terminus_family
--------------------------------------------MNTFEPGDFYVLRTPL
L-----ERSYLELPVGVAQGTGQV------------------------RQHLQAVYALP-
ALQQALYIASPDLFAQLDRWHTLAALPAPNKKQRKDLQNLEQKLWMFLARAAYRCTPFGT
FAAVTVGEFRLQRHSSLAL-DKLGNMRTSSRLDMV-YLLRLRAALEAEPKIREQLRYFPN
NTLYRNGDDMLCSFF--------DEQTLQHVASSKEYHEVAWELFTACGQAGGMRIGEMI
AYLMT--DPELTEADCREFVEYLTSHHLLISELYPSLNGAEYLEQLHTSV-----EQVPA
AH--------E----YLPIIGHIRKQLALI--DATPDPAQSLGLYQQLVDYLSSQPFYQT
QETGTTAHP--NEKTVSKKELIQVDAFR---DENGL-----------ELSKTVPRHLVRQ
IETLIDHVGET----PPPKTDLTSFAQAFFKRYE-NEAVPLLTAMDEVTGLGY-PY-GKR
VAALPTYLQELGVVIGEGGAMPQAADPKAGQTSA---------LDALLEQKYVEALQMGL
AEIHLSKG---EVQSLKASQLPTKE-KPTSLPPAMVAMGKLLYRAPDDLEHNPKQGTPRN
FRFQLYHASGPV-VGNLLGRFCYGSPLLQQQLSATIAQV----EPDNDQV-VYAEVDHLP
GQ-RVGNVIIRPRLREYSIA-LGGAN-------TNTP---HQIPVADLWLSTPD-SK--R
LVLHSR-KLNKQVVPRMSNAHNYA--HNAHPLYKFLCDLQ--YQQEYRQLPPFFRAQRWQ
QRS---YLPRLVYDDSLILSPRQWRVSYKV--LEAVQLQKKEDLHAVST-WTHKIERLR-
-QQLRLPQTVLLVEADNKLYIDFAHPLSIGVFLQKVFD-----RKELVLEEVIEQ-----
---DLPSQP----YSNEMIFPIINTTPPSH--------KQA-----PVLAAQTLPQSIQK
NFAFG---SEWVYFKIYLGALGSDRLIAEDLHPLSKELRDSEHIDQ--WFFIRYT-----
DPDYGT-HLRWRLHIKHY-P---KEFGEIVQAFSQKLLELKNQG--KIIHYVPDTYQREL
NRYL--PYNMALSEEWFALDSDFVCHALALLAND-------EAANDTLKSAIAIKRIKAL
LQA-FDLPEET-----CQQITSQGKTNFSREFGLDVHPQAQR----------LKKALAKQ
ALPEDF------NMQHQWAF--------------------IQLTDQE---KPLAQQIKAN
LQQHGASEAQLRSLLGSYIHMFNNRFFA-SGQRLEEM-----------WGYWRLE-----
--------------
>NZ_AAWS01000004.1|c1|63390-66569|-|ZP_01687780.1|lantibiotic_dehydratase,_C_terminus_family
------------------------------------------------------------
-----------------MDTV---------------------------RQHLQAAYRLP-
ALQQALYIASPDLFAQLDRWHALAALPAPNKKQRKDLQNLEQKLWMFLARAAYRCTPFGT
FAAVTVGEFRLQRHSSLAL-DKLGNMRTSSRLDMV-YLLRLRASLEAEPKIREQLRYFPN
NTLYRNGDDMLCSFF--------DEQTLQHVASSKEYHEVAWELFIACGQAGGMRIGEMI
AHLMT--GPELTEADCREFVEYLINHHLLISELYPSLNGEEYLEQLHASI-----AQMPA
AQ--------G----YLAIINHIRRQLALI--DATPDPAQSLGLYQQLAGYLSEQPFYQA
QETAITAHP--NEKTASKKELIQVDAFR---DENGQ-----------ALSKTVPRHLVRQ
IATLIDTVGEV----PTTKADLSTFAQAFFKRYE-NEAVPLLLAMDEVTGVGY-PY-GKR
VATLPTYLQELGVVVGEGGAMPQVA---------DPKAGQTSALDALLEQKYVEALQTGA
PAIHLSKG---EVQSLKASQLPTKEKPRSLP-PAMVAMGKLLYQAPDDLEHNPKQDNPRN
FRFQLYHATGPV-VGNLLGRFCYGSPLLQQQLSATIAQV----EPDDNSV-VYAEIDHLP
GQ-RVGNVIIRPRLRDYSIA-LGGAN-------TNDV---HQIPVTDLWLSAQDGGK--R
LVLHSR-KLNKQVVPRMSNAHNYA--HNAHPLYKFLCDLQ--YQQEYRQLPPFFRAQRWQ
QRS---YLPRLVYDGTLILSPRQWRVNYKA--LEAVQLQKKEDMHAVST-WTHKIERLR-
-QQLRLPQAVLLVEADNKLYIDFAHPLSIGVFLQKVFD-----RKELVLEEVIEQ-----
---HLPSQP----YSNEMIFPIINTAAPSS--------KQS-----PAFDAQTWVPDVQK
NFSFG---SEWVYFKIYLGTLGSDRLIAEDLHPLSKELRDSGHIDQ--WFFIRYT-----
DPEAYGTHLRWRLHINHY-P---KEFGEIVQAFSQKLLGLKQQG--KIIHYVPDTYQREL
NRYL--PYNMALSEEWFALDSDFVCHALALLAK-D------EATNDTLKSALALQRIKAL
LQA-FDLPEET-----RQQITSQGKTNFSREFGLDVHPQAQR----------LKKALAKQ
ALPPWLPP----AYRLLFDQ----------------------LTEQE---APLAQQIKAN
LQQHGASETQLRSLLSSYIHMFYNRFFA-SGQRLEEM-----------WGYWRLEG----
--------------
>NC_013730.1|c7|5725942-5729124|-|YP_003389481.1|Lantibiotic_dehydratase_domain_protein
---------------------------------------------MQDNVLPKGILRTPM
F-----SYRFYERILDGSLSL-------------------------------NELLNNP-
IFSNALYLASPELHAYSHQLLANPLA------DPRRYNKLKNTVLKYAYRAATRCTPFGL
FSGLGVIDFTHNPTRLIMS-EPDRHR-THVRLDMD-FLGRLSQQLTTRPYIRPYLTYRTN
TSLYCLGNSYRYINYQY------VDGLRKFDLTAVEVTPTLETIIATAGT--GAPFDVIA
QSIVD-ED--VSYADAAEFISDLIDQRMLGSELEPSTTGQEAGHQLLETLMALSKRVTDP
DH-------RQ----LLASLILEVGDLVQLVGGLNQVSTHRVEAYQTIIDKARQ------
-----LCPD--TN----EKYLIQCDTVM---QFEEH---------A-NLSADLLVN-VQE
GLDAFRQLSVP----ARPNPQMQQFIKRFAERYG-DQEVPLTEALDVEMGVGYGAM-ADA
QADFAGFIDRL--------PLEQPQAKGLTVEWDNR-------LHNLLAQKILAAYQTGS
DVISLSEK---DIHQLTSATKNQA------PYNTYSCGFSLFKDD-------------AG
QPVVLINGYGNHTGAALIGRFCHTDPQIHALAQHITDTE----TALNPDA-LVAEVNHLP
QD-RLGNVMQRPILRPYEIP-FLANS-------FLDAD--HQLAVADLLVSVQS--D--K
VVLRSK-QHGKVVLPYLTNALVHE--KESLPIFHFLGDLQ--L-EDNGFQAVVNMGILPQ
VFP---YIPRIQYK-NVILKRAAWILQETD--IE------KISKVSGDA-GLDQFTAIA-
-DALGLPEQFVLAHFDNQLPICRTNPDSVQ-LFIDEIR--G--HKKVVLLESLLS---RY
D--SFVHTADGEPLNNELMAF-FSNGDKARQ-------QKS-----KIGWPSMARLGTKR
DFLPG---SEWVYFKVYTGFNVSDKFIAT-LESTVAPLLTADLVEK--WFFIRYN-----
DPE--P-HIRLRLKLAD--P---STISQVLARLNQTLEGLKQDG--RAWKIVIDTYSREL
ERYG--ETSIDAAETVFFADSLAASRIVR-------------AVPDEWRWLAGMASVDAY
LTS-FGFSQSQ-----KLSLVTRMKDGFELEFKAGKEARKHLNSVYSA----HKELIAYL
MDPECSERSV--PLIQQINR----------------------INAYR---QEQQQTAIDQ
IQRSATDERQLESRLISLIHMSINRLFRSRQRLFEYSFYHFLKNYYTSRSFINPVLNSSK
PELV----------
>NC_013730.1|c7|5734645-5737812|+|YP_003389491.1|Lantibiotic_dehydratase_domain_protein
----------------------------------------------MNSLFDFFVLRRPV
Y-----PLTKLLTLQKNLLNNSL--------------------------DSLLREWYTDP
LAQEAIYVASPGLYKRFQQWRAGE--------TLSEQTKLLDTLFKYAIRMSTRCTPYGL
FAGCSVGDFHDQFSRLSPG-RSNTLV-THSRLDME-CLMAIRDWLLGQSVVRNELIFYPN
SSLYKVGRNHRYIEQQW------EGQQRRYFISAVETDEALDSLLTTARM--GVTIPYLV
DFLGQ-MG--AETIEAESYVDQLIETQLLVSTLEPTVIGDDYLTVMIRTL-----SSMPA
TA--------S----LVAQLIRLQNVVTSS----TDRAAVGQEILRWLAGNQIT------
------LPG--TD-------LLQVDSFFTGTDTPQA---------KPHLDKGLVHQ-LQQ
QIRKLFVLNQ-----PYSSPDFDDFKNRFYNRYE-DEEIPLSMALDQEFGVGYGNQ-THL
GVGYAPMIDDLSLPTLETTVPATNSSW----------------WQNLLLEKYSHTLRTGT
HEIEISDS---DLAYIDQRRVDKLI-----EPDSFYLFGNLLSAPGESVDHALRPG--GN
YRFNLLACKGPSAI-TLLGRFCAGDPDLRASVQACAQAS----AAHHPDV-VFAEIVHFP
ES-RAGNILVRPTLYKYEIPYLGMAS-------VPPD---QQLPLDDLMVSVRN--R--H
VVLRSK-RLNKRVIPRLSNAHNYQ---NGLPIYRFLCDLQ--H-QDSHLNVQWNWGILAE
QA----YLPRVRYQ-NIILSRATWRLKADE--LE----------------LENPMRLAVE
LSRRNIPEQFVIAVGDHELVITRNAPESLR-LLMHELR--K--SDTVRLYEFLQA---ED
V--CSVRMP-KKAFTHELIIP-FYNAD-----------APA-----ISSLAAYSTDLPQR
RFSVG---SEWLYLKIYTGEKSSDGLLTQTLYPVIQRLLNTSIISE--FFFIRYK-----
DTD--P-HLRLRFRGNP-HL---EFYHFVIREIERAIRDDVQSG--VVHKLQTDTYQREI
ERYGH--RQIQLCEGLFYTDSLSTLFFLSRT---G------EAFNEEVRFTYAVGKIDRL
LSG-SSLSLDY-----RWKLLNNLKDSFFDEFNGKTELRRQL----------NDKYRNYR
SALNTAF-----GIDYQFML----------------------TNEPN---AASQLTLLKQ
LTASYESENQLMSTLTSLIHMIVNRIFPSKQRAYELIIYHCLAKHYDSIRARTDQTTLTN
QDAPIVQPAISDIP
>NC_013132.1|c1|1748890-1752006|-|YP_003121134.1|Lantibiotic_dehydratase_domain_protein
----------------------------------------------MITNKGFYLLRAPL
M-----PVEFLTRFLQLPYEA-----L---------------------AEEIKQVFTTP-
YLAEAIYIASPELSSELRKWQEGQVM------SEKDQEKLVLSLFRYLLRMSTRCTPYGL
FAGCSTGYTGSATNVYIQPVQAHK---QHCRLDMN-YVAELAETIARIPAVQEQLRYFPN
NSIYRTGDTYRYAAFTV------KNKFRQYDLTAINHSVYLEGVLTLAAK--GATRKALY
QHITD---DDITEEEFRVFIDELIDSQILISELEPTITGEEFFHVLIDKL-----SRLEN
IR--------P----IYELLCAIREQLTVS--------QSGIEKYLHTHALVKQ------
-----LLPETKNK------DLVQTDLFL---ATTDN-----------TISNGVIDD-IQA
QMEVLWKLSVA-----NKQPDLLHFSKAFSQRYE-EQEVPLALALDTEAGIGYGAYTSHY
AAYAPLLEEVVTKTTGTADTIPWNN------------------MREFQLKRYMACLQAQQ
SEVVLTDE---DIDYLSTTSTIPIP-------DSFYMMGSIVSESGATMDK-------GD
YLFDFTSCGGPS-AGNLLGRFCHGDAALKELVRECLDEE----AGQQPDV-IYAEIIHLP
EA-RTGNILLRPQLRDYEIVYLGNGS-------VPEE---KQIPVTDLLVSVQN--E--Q
IILRSK-RFNKRVIPRLSSAHNFM--KGSLPMYKFLCDLQ--F-QQLRHATGWQWQ-LPV
EAP---FLPRVRYK-HIVLQKCTWLIYSKD--HP-----SLQKNATVQM-HFKAFSAIK-
-EALKLPRHISIADGDNELFIDLENASCVHLMVTTLLK-----REQLTLQEVLQT---PE
Q--CWVLGD-AGRFTNEIILP-FKSNT-----------VQA-----ATVTREQTTDQLQR
HFPPG---SEWLYVKIYAGINTAEKILTTVIKPLVEQLEANDIIEQ--WFFIRYT-----
DPE--D-HIRVRFHHATR-K---DFWTIVLAELQERLAAAIDPG--LIHRIQTDTYAREL
ERYG--ATTMVVSEHLFAYDSEAVLGCIDLL---E------GEEGEHFRWLLAIRGVDML
MDD-FGYTLAR-----KSTYLKRLQQYFFREFGAGQPLQTQLNAGYRKHMRQISSFLDPL
QDAEN-------EIEEAIQL----------------------LEKRS---SHIRAAI---
---QKVAVRTWDDLLSSYIHMFLNRMLSSNQRKHELVIYHFLSKYYESRLAMLKQQQLS-
--------------
>NC_013132.1|c5|4158312-4161440|+|YP_003123060.1|Lantibiotic_dehydratase_domain_protein
-------------------------------------------MSTPYSFDNRLVLRTPR
F------------PLMQIPTNDQ----------------------------LPALLHDN-
AFLEAIYLASPVLYSECIKWREGGIT------NKKDIDKLTRSLTKYVIRMSRRCTPFGL
FSGCAVTAWSEQPTAVTVS-GTTFS--RHTRLDMH-YLCALSQQLATMPGVKEYLLYMPN
SSVYTIGDELRYVEYLY------VGGTRLHQISAVSASEYLDKMVTAAYN--GATIGQLC
NWLAD-DN--IAEEDARIFIDELIAAQILVCEIEPAITGKEFLQQVIEVL-----QRIEL
LD-------PA----VVKDLLTVLSKVATLLEQLDDTATNSIERYREIMQLLDM------
----LEVAY--DE-----SKLFQTDVVK---HVSGN-----------GINIDVQNQ-LQN
ALNVMNKLSEY-----KANPHLETFMQRFRERYE-EQEMPLLEVLDGETGIGY-VD-SSS
TNIAPLLDDISMPGKMNEVRFSWGA------------------LEQLLSGKLVDMYAEGR
QSIEINEE---DLKDFTANWHDLP--------PSFSVMFRIVDE--------------KD
NAIYLESAGGSS-AANLLGRFAYADNAINRLVCDITEKE----QAMDPEV-VYAEIIHLP
ES-RTGNILLHPVFRGYEIP-YLAKS-------SLDKE--QQIDLQDLYISVRN--N--R
VVMRSR-RLGKQVIPRLSTAHNYT--NNSLPVYRFLCDLQ--L-QDKRGGMSFHWGALES
KYR---FFPRVTCR-NTILHLARWTFAQKD--IA------QLLNESGME-LTAALQAFR-
-ERWKLPQTIVLADGDNELMIDFSCHSMVS-AWLSTVK--G--RQTFELRESLNN---QQ
---CITDEN-GAPYVNQLVAT-LGKDTASYA-------HLK-----TAAPQQMASEPAQR
DFTPG---SDWLYYKLYCGVKSADKILLNALRPLGAELVDAGLTDK--WFFVRFN-----
DPD--F-HLRVRFHLTD--V---SKIGEVTAKILASLQPFTAAG--YIWKVQLDTYSREI
TRYG--ANAIEQAETLFYHDSVAFAELLHNT---W------GDQREEIRWLWSLRAVDEL
LDC-FMFSLHE-----KHTLLSGLRDDFRAEFNWSKEMKQQLDNKYRNNRQAIASFMERN
ASQSDSLQ----PLMKILRE----------------------KSLNI---AGVAHDI-LM
MESAGKLEICIRDLLRSYIHMMINRTTITYSRKQEMVMYDFLARYYQSALARTKTIAWEE
--------------
>NC_013061.1|c1|662383-664656|+|YP_003090841.1|Lantibiotic_dehydratase_domain_protein
-----------------------------------------MKKTNPYLPFEQFVYRSPL
L-----PFNTFIQHLTEISASEE---------------------------RFKNLLSNK-
IIWEAIYLASPVLFEELLKYLQKGLP------DKKEEERIKYSMVRYLGRMSTRCTPFGL
FAGCSVGRFNEQTTIALNK-TEQYQ--RHTRLDMT-YLCALAQELAGSPEVKPYFRYFSN
TSIYRFGDKIRYVEYFY------RSTRRIHRISAVDYSEYLDKILREASQ--GRKINELA
ELIVD-DE--ISMEDASAFIDELINSQLLVNEMEPSVTGKEFLYQAIQKF-----EEIEK
TIPGKKEYISG----SLQLLKQVSKVLEDI---DKNVIGNTLHLYGDITSEIKR------
----FKTTF--EP-----KYLFQTDMIK---PADTS-----------FLGRDVIDD-LKG
AIEFFNKITAK-----PGETNLSKFREAFRDRYE-DREMPLLQVLDNEAGIGYTQA-GST
GDINPLVDDLM---------IPQPGSSNGNKVIWSG-------LQSILLKKYIEAKTTNQ
YTIELSDK---EFEHLTTQWNDLP--------LTISAMFRIVQDDKN-----------GR
TVYMK--TAGGSSAANLLGRFCYADKRIEEHVLDITQKE----EELNPDV-IFAEIAHLP
ES-RTGNILLRPVLRPYEIP-YLAKP-------GVEKD--YQIALSDLMVSVRN--G--R
ILLRSK-RLNKEIIPRLSSAHNYS--FKAMPVYHFLCDMQ--V-QNGRSAVGFNWGTLAN
EHN---WLPRVKYN-NIIFSVARWTIKREE--IK-----VFIETKDDQV-LVESVTAWR-
-LPLQIPKHVVLDDGDNELFVDLTNALSVR-TLFSVVK--K--RNSFLLEE---------
------------------------------------------------------------
------------------------------------------------FLF---------
NPE---------------------------------------------------------
------TAVVKGEEGVFTNE----------------------------------------
------------------------------------------------------------
------------FIVSFYKE----------------------KQNNI---NNY-------
---------------------------G--------------------------------
--------------
>NZ_ABIB01000003.1|c1|30625-32904|+|ZP_02161440.1|lantibiotic_biosynthesis_protein
----------------------------------MFNDKLKQMSKNPYKNFSKYILRTPL
F-----SFTSYQELTSKKEIS---------------------------DEDFKTVCENP-
VVREALFLASPSLFEEMNRWLAGEMD------DAKKEEKLRYSILKYISRMSSRCTPFGL
FAGCSVGEFGEETDIKLKGSAQNK---RHTRLDMN-YLVALSQDLVTNKKIREQLLFYPN
SSIYKAGPQLRYIEYKY------FNSRRHHHIVAVDDTEYLAVVLEKASN--GASLSELA
KLLVD---DEITIEEATEFIEELVSSQLLISELEPSVSGPEFLEQICNVL-----ERLEG
VE--------G----ILAALKEADNKINKI----DESIGNNPKVYLELSEFLQQ------
-----------LETDFELKFMFQTDMVL---QNTKN-----------TLSSTVVDD-IKK
GYALLNRISF-----PQSTTTLTKFRDAFHERFE-EREVPLSTALDVEIGIGYKQD-QGA
GDVNPLVDNIVIPGRQSKHQMMEVRWSP---------------INSFFQDKLIEAFKNDD
YIITINED---DFKDYDLNWNDLPD--------TMSCMIEILEDKN------------GE
HKIKFS-GGGGSSAANLLGRFCHGDEELFAYTQEMVDME----AEMNSEK-ILAEIVHLP
ES-RVGNILMRPDLRKYEIPYLAKSI-------KPEE---DQLPIDDLMVSVKN-HS--K
VLLRSK-KHNKEVVPHLTNAHNYS--HNSLPIYHFLADMQ--T-QGIRSGVGFGLGPFAN
DYP---FLPRVEFN-NLILHDATWNLKKSH-------IEPLLKVKKDNDKLTEAIQTLR-
-DSLKIPQYVMLADGDNELLVNFENLTSVRMLLNTVSK-----RGSFKLTEFLFS-----
------------------------------------------------------------
------------------------------------------------------------
-----E------------------------------------------------------
------RGVVKEGDEYYTNQ----------------------------------------
------------------------------------------------------------
------------VVISFYNE----------------------QKLTQ-------------
-----------------------------SKQSNE-------------------------
--------------
>NC_013061.1|c1|664649-665602|+|YP_003090842.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MDK------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------GIKR
TFIPG---DKWIYFKLYTGYKTADNILSKTLPAIISQLNTENVLDK--WFFIRYS-----
DPK--F-HLRLRFCLKD--A---KNISSVISLFNREMSPYIDED--LIWKVQIDTYQREL
ERYG--TTTMEHSESMFHFDSEAILSILSILSIPE------YNESDQQRWLLALKILDAL
LFD-FELGMDQ-----KIALLTEL--SEDFKKEMGFTIKGYKLQLDKKFRTHRKLIEEIM
GTPEQASWAI--PLMEIIRQ----------------------RSLKV---KPIAGTL-LQ
MEMNQKLEVSLHSLLRSYIHMTINRLFRSKQRVYELVIYDMLERYYSSLKARSKNTAGKM
HRASIEALPQVVIT
>NZ_ABIB01000003.1|c1|32897-33811|+|ZP_02161441.1|lantibiotic_biosynthesis_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNNEIQRNFILG-----------------------------------------------
------------------------------------------------------------
--------DSWLYYKIYTGPKTCDAVLTEIIKPIAEQLIAHGIIDK--WFFIRYA-----
DPK--H-HVRVRFHYTK--P---ENVGFIINGLYPKFKEFIDQD--LIYKIQIDTYQREI
ERYG--SNTMELAEAMFYHDSKMIVDFIDMI---E------GDEGEELRWLFSIRAMDSH
LTS-YGYNDDE-----KLELLDRLKTGFGNEFGMSRPLKKQLDDKFRAERKKIEEFMVFT
AEENPDYE----PILDVLAQ----------------------KEEGI---KDIAAAI-IK
HKEDETLMMPINDLMGSYLHMLMNRLFKSKNRIHEMVCYDFLYRYYKSMIARKKHMNKNK
NKKK----------
>NC_006448.1|c1|104847-107651|+|YP_138642.1|lantibiotic_biosynthesis_protein
------------------------------------------------------------
------------------------------------------------------------
----MLLVANPQFFHNLT----------------KEKIYKNSTFRNYVKRSITRATPFGL
FSSIGVGTFSDISYPQKIG-ENYT---KKISVSGE-WLSSICMMLENEDSVLLQLHIQWN
QKVLELSDKYQLSNVNY------WGISEISKDLFIKKTGLLEFIQKLTYK-SEVSVLELV
QTIQS-KSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDLDDLTNIL-----KDINN
QR--------K----LTEDLLQIKNSIEQY---AKLELGEGISQYTEICKKMSY------
------IFNDEKQ------HYLKVDLVN---CCDS------------VLPKNLKKK-MED
FVNFISKINLT---KGYRNRELESFTEKFVEKYGEYVEIPIKELLDGNLGLGL-PK-PSL
GAQGKPSSSVEEQK-----------------------------FLYYLSKEVFKAIKNCK
KEIDISNI---PLGLLYPNSDRFVA-------NQLELYCAIKNFE-------------SQ
SVISVVPNTGSDMIGKSIGRFASYFPNSY--------------ISLDSQL-NNVELIEFS
RDSKNLNVMSAKHAHSKKL--LLSYD-------DNDN---TSIELDSLVVGVIKIDQRYK
LYFRDL-RTGSIVNFVTTSMLNHKSNGVFSDLARFLLTVS--LEWQDNPFSVFRIIENFD
FLP---YIPKIKYG-DIILSEEKWVLSDID-----------------KS-DLSSINQWK-
-KDFDVPRLLYFHKADERLLVDLENDLDIQWLLKQNVD-----KLYFTRFEKCDG-----
-------------KNCEFIFG-FENYQNSINHYS----MQE-----KSVRRLTNNFYKNY
VKTFS---SDWIYFRLYGINSSILPELRERLLLFTDELLVEKLISD--FHFVNYR-----
DKD--NGSLRLRFKINN--D---NNFEDLRFRITHWIDFLLESGFCFCNDVSFNLYEREI
ERYGG-DSFTTVCERMFSIDSFLTLKLFS-------------KKLLNDKDLLSVLHSTFL
YVRLLGIPLKR-----LLELLKGN-LTQNRYRKSFKKLFPNNTIVVKE----FKEYFDYK
------------NQFEIFNE----------------------VFREF---PPIDGYF---
--------EGKNDIVYSLLHMHMNRV-G-IFPYREKEYLYFIMYIAEALNNYEEFT----
--------------
>NC_010582.1|c1|144296-147211|+|YP_001834862.1|lantibiotic_biosynthesis_protein
----------------------------------------------MFKIKDNYIYRQCV
N-----DSILIEKLNENN----------------------------------LEIFFDSK
IFQEMLMVANPRFFNELT----------------KEKIYQNSTFRNYAKRSLTRATPFGL
FSSVGVGSFSKVSYPQQIR-ENYS---KKVSVSGE-WISSLCMMLENEDSVLLQLHLQWN
QKVLELSDKYQLNNINY------WGVSEQSRDILIKKTALLEFIKKLTYK-SEVSVLDLV
QEIQT-KSPNLETQKIIDYLRNLIISEFLFTNLRKVVINHNCLDNLIYIL-----SSINE
QT--------K----LTTDLLQLKSCIEKY---SKSELGEGILQYAEICEKMSH------
------IFNEEKQ------RYLKVDLVN---SYDS------------LLPKDLKKT-LED
FVNFISRINLG---KDYRNKELISYTEKFVEKYGEYVEVPIKQLLDSKLGLGI-PKQNLE
PYSILSSVAEQT-------------------------------FLSYLSKEIFKAVKNNK
KEIDISNI---PPELLYPNLDRFAV-------NQFELYCEMKNFG-------------EQ
PVISIVPNTGSDMIGKSIGRFASYFLNSNIELDSRV---------------DNVELIEFP
SDNKNLNVMSSHHGHSKKLL-LSYED-------DFDI---DSLELDFLVVGVERVNEHYK
LYFRDL-RTDLIVNFVTTSMLNHKSIGVFSHLARFLLTVS--LEWQDNPFSLFRVIENLD
FLP---YIPRIKYK-NIILSEEKWILSDVD-----------------KK-DMSTISQWK-
-KFFDVPSLLYFHKDDERLLIDLKNSLDVQWILKQNVD-----KLHFTRFDKIDG-----
-------------KNCEFIFG-FENPRNSVYPHS----VSE-----KTVRRIENDFYKDY
VKTFS---SDWIYFKLYGINSSTMPELRENLLIFTDELLAEKLVSD--FHFVNYN-----
DGG--DGSIRLRFKIMN--E---DDFEKLRYRIIHWIDFLLNHY--FCKDVSFNLYEREV
ERYGG-IGFLTVCERIFSIDSYLVLKLFS------------KKVLKVDDYLSVLHSIFIY
IRL-LGISPKQ-----LLKLMKDT-FTQNIYRKSFKKVFPNNAKVIKE----------FK
QYFEDQ------SKFDIFNE----------------------VFKSF---SPIEKHF---
--------EYKNDMIHSLLHMHMNRI-G-IFSLNEKEYLYFVRYILEVLNNYEKYN----
--------------
>Z49865.1|c1|3410-6313|+|CAA90025.1|PepB
-----------------------------------------------MKLFDWYMVREPI
L-----NINDLKIIKKNNLNDDE---Y---------------------LNMLITFIFDK-
GLDVCLCHANIELFSIIKNYQNINL-------SKKKKKNLSLSLYNYITRMILRSTPFGF
MSSINIKALD--TTNPIWN-NYAKK--YNLEIDSR-LLYPLINKL--NIVVKNELYLKKN
SNVYEDTTHFYIPYQMQL-----EGTNTVPNNISVKKNELSKFIFTKLNN---MLYKDLV
KLVED-EFD-ADTIMVETYLDKLIEENFIVTELEDAISHKDRDIFLIKKL-----EQKGF
SN-------SY----YYKALKEIYDIRQIM--EKGNIHDDILYRIIEVKKFLKE------
----KFNLD--VH------NIFKVDTI----DTNIE---------I-DLSKSEINN-IKK
VIDMLLYLPSD------YDNSLQEYKNKFLEIYGQDEYVNILKLLNKNTGIQY-PI-NIY
NNKAFQYNNE---------------------------------KVYSLLTEWQYKAIRDK
TDIILNEE---RIELLKRVGKKPID-------KSFDMVFTVTKDGF------------NN
NIYHLNDNVTSLKATNIYGRFRYLNTKYFEEQLNK--------FPDSVGV-PSDNLNYHH
PNPIIDNVKFKSIFFD------------------------KQTSFTDIFVFLGE-DL--N
FYLKNL-KNGETFIPKISDMHNTQ--Y-SPNLIDFLSKV-----ENQFIQEYWNIENYLS
DYT---FLPRIVYK-NIIISPRKWKINFLE------------KIENYSQ-FIKIFLAKK-
-DELLIPNRFYIQQADLKIYIDLENERCME-ILFKESK--K--NISIIIVEIEKN---LL
Q----------NKKVKEAVFS-IKSDLHQE--------INY-----NYMMKKDHIPNLSK
EILYID--DGWISVNLYYNDNNINKFIGEFFLTNIFESENFSDI----KYFIRYA-----
DEK--E-HIRLRMKLEF----------DQVKSALHLFKEMVDLN--YIIDYKIVPYYRET
YRYGG-KEVIEIVEACFEKDSEIVSKFYA-----Y------SNISSKEKLYFNILNIFDI
LSY-FSESIND-----KITFFKDI-NHKVQNKKIYRKYKDNL----------------LK
TLNGSYEE----NYNSYLSI----------------------RRKEY---QKLKEAL---
---KYEEVNYKKSIILSIVHMFNNRLSG-INREHEELVMEFASRTLIDYQNMRKYL----
--------------
>Y14023.1|c1|3083-6013|+|CAA74350.1|EciB_protein
-----------------------------------------------MHLFKWYMIREPI
L-----EINKLEDIQERRDNNED--KY---------------------LNKLIDFIFDN-
ELALPLYHANSNLFNMINNYKRKEL-------SKKKKKNLILSLYNYITRMIFRATPFGF
MSSINIGSIK-PNEMTVWN-NDTQK--YNLDLDNR-VLYPLLKNLNKD--IKNKIYLRKN
YYIYKDYTHYYIPYQLNFD----KLIVNANNNINIERNELSDFIFSN---LDSILYVDLV
DLIKT-KFN-VDSKTVENYLDKLIQENFIISELEEVINHKNKDIYLINFL-----EKKGV
SP------TNK----YYQMLKSVYQFRVSL---KNNYNNKSLNQLMKINETFKK------
----TLGFD--SS------NIFKVDFVN---KYSEI-----------NFKEKDIQN-IKK
VINMLLHLPEN------YADYLTNYKSEFSEIYGQDEYKNILELLNKNLGIEYTID-NKD
NEKFKENIQKS-----------------------KK-------NIYSLFSEWEYKAISEN
QDIVLTDE---KIQSIKSLGEPPVD-------ASVDMIFTVTQNEN------------SE
YIYHLNDELTSAKVTDMYGRFRYLMNEDFEKALNK--------FPHDIGI-QKVNSNYKH
PNPLIQNVKNSDYLSS------------------------YSSDFKNYFVFLGN-DL--N
FYLKNK-KDETIFIPKISDMHNTD--Y-SPYIIDFLSKI-----EKQFIKEYWSIENYKS
SFV---FSPRIVYK-NIVISPKKWKLTNFD------------KMDNYEN-FKKLFFEKK-
-VELSIPDQFYIINADLKIYIDTQNTWCLE-LLFKEFK--K--NEHLNIIEVES------
---NLLNN----KKIKEVVFS-AKSDICQS--------INI-----YEENKNNINLPKEI
LYIT----DGWLSVNLYYNENNISKLIGDF---FYRKLFENEIFKNSIKYFIRYI-----
DDK--K-HIRLRIKINI----------DEINKVAKILKEMVDIN--YIKSYKIVPYYRET
ARYGG-KEIIDIVEECFEKDSKIVSKYYA-----D------KNFSSDDALYFNITNIVDI
LSY-LTNSIDA-----QIDILSDI-SHKKENKKIYRKYKNNLMKIVEG----DVN-----
------------KYNIYLNL----------------------RKYAY---SKLKFVL---
---SDKKINDKKDIILSIVHMFNNRFIG-TDRKYEEFVMELLSRTLIDYKNKKEHICNNS
--------------
>NC_013132.1|c11|6803333-6804169|-|YP_003124959.1|hypothetical_protein
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MQRN------------------------
------------------------------------WL---------------------S
AHLFYRGD----------------------------------------------------
------------------------------------------LRFLLLEM----------
------------------------------------------------------------
-----------------------------------------------VLP----------
----FLRDTPY---------------RGFFIRYGEGG-----------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------PHIRLRLLP
GS--------------------------------------ADIALIQSQLI---------
-------AAGRVIEGLTIQFIAYE-----PEIARYGDEDS------------IAWAEEQ-
------FMCSSAYVLDVLNNKREWDASGAL------------------------LEALK-
--------------------MNMAIACALD------------------------------
------------------------------------------------------------
------------------------------------------------------------
VPA----------------H---EMIATCRQFIDQWLPRL----------YDRSKFAAEQ
KQY----YTTQLDHRFSHYAPLLLPATAT-------------------------------
------------------LWEALH------------------TGKATP------------
------------RLQAFMQS----------------------NRRIF---QEYSRLG---
-----FDDHSMRDITGSFMHMGHNRL-G-VSNLDEAYIMFFTLKCLENVYAGGKSER---
--------------
>NZ_ACNK01000131.1|c1|1175-4246|+|ZP_04075567.1|hypothetical_protein
---------------------------------------------MKHQLLNTYMYRKPI
L-----TLKEYQELFDSKIST---LEY---------------------ENKIKEIFSDG-
KLKLAIYISSPSMYEALNRLDSL---------DAKKKRNFLHGITKFLIRMSTRPTPFGL
FAGMGIESINNNGKGSFNI-D------SYFRLDFS-TIYKIVEVLENQDEILKKANIRFN
NLLYKHGNRLKLPYQSNVHNK--DNIDEHMKIMTVKNSPVLDYIRKITRN--DINFEQLV
DKINK-EF-NTEDTTSKGYLKKLIDNDILFSDLRPALSSNDPFKYLITIL-----EEKNI
NH--------E----LLDNLKQINFSLDKFNLTKEEISVKELSNFKSLLKTFKL------
-----------CG-----EKDIRVDAKLTN-SSEL------------ALGDEDITN-LEE
LSRIMSYLGCI-----NPLQVLNSYRDSFIEKYGPYQEVPILELLDEDLGLGK-PN-DYV
TNGNSQPQISENLR-----------------------------AVRNLIQKWQTEALINN
ENIILDEDKIKEIKKHISRNDIEKE------NIDLELYFNYFQCK-------------GA
NKFYLVPNTGSTQIGNTYGRFKYMFNKNEINQLKDFNEFI---EDQDSNI-KFADLRINP
DNSSLANIMNSPSVYKSEIN-LCTNP-------SESCS--NNIDIENLVVGINN--N--K
FYIRDS-SSNNIIIPKISNMFNY---ENANLIYRFLADVG-------ALYSGI-WGNIHH
HFYDSHVYPKIVYK-NIVVSPKRWIFHHTF-----------TQKMSEEE-FILVFLEWC-
-NRNNITNYIYLAEYDNKLLLNIKNKLHLS-IIFQEFSKLKL-NDRLSLFECEED-----
---TFVSSN---QRFEECVFS-FRQIDRKKIT------FTN-----SLNRNYKYINDMNR
VKLLG---SNWISLRVNYVDSRVEEFLSCGYKEFYKHNKDINKIEK--GFFVRYA-----
DPT--P-HLRIRFKLAK--N---EKYNTFLGNITEWLTNEREKG--LVNDFHFVSYNPEI
ERYG--DFLIDKAEDIFSIDSLIVADSFE-------------GDVPLNRELFCCLNIMSI
LKG-FNLNFAS-----QLEILNMA-IDPKIYKEAYRENKANLDPIITN----IYDYIEIP
MSEKL-------IIPTTFND----------------------RDNVI---RKYAELI---
DANEDVLTNVKSDIIASILHMHCNRLNG-INRDLENKILGMCYHTIKKYMNLIKYKYNVL
V-------------
>NZ_ACNF01000121.1|c1|1046-4117|+|ZP_04105296.1|hypothetical_protein
---------------------------------------------MKHQLLNTYMYRKPI
L-----TLKEYQELFDSKIST---LEY---------------------ENKIKEIFSDD-
KLKLAIYISSPTMYEALNRLDSL---------DAKKKRNFLHGITKFLIRMSTRPTPFGL
FAGMGIESINNNGKGSFNI-D------SYFRLDFS-TIYKIVEVLENQDEILKKANIRFN
NLLYKHGNRLKLPYQSNVHNK--DNIDEHMKIMTVKNSPVLDYIRKITRN--DINFEQLV
DKINK-EF-NTEDTTSKGYLKKLIDNDILFSDLRPALSSNDPFKYLITIL-----EEKNI
NH--------E----LLDNLKQINFSLDKFNLTKEEISVKELSNFKSLLKTFKL------
-----------CG-----EKDIRVDAKLTN-SSEL------------ALGDEDITN-LEE
LSRIMSYLGCI-----NPLQVLNSYRDSFIEKYGPYQEVPILELLDEDLGLGK-PN-DYV
TNGNSQPQISENLR-----------------------------AVRNLIQNWQTEALINN
ENIILDEDKIKEIKKHISRNDIEKE------NIDLELYFNYFQCK-------------GA
NKFYLVPNTGSTQIGNTYGRFKYMFNKNEINQLKDFNEFI---EDQDSNI-KFADLRINP
DNSSLANIMNSPSVYKSEIN-LCTNP-------SESCS--NNIDIENLVVGINN--N--K
FYIRDS-SSNNIIIPKISNMFNYE---NANLIYRFLADVG-------ALYSGI-WGNIHH
HFYDSHVYPKIVYK-NIVVSPKRWIFHHTF-----------TQKMSEEE-FISVFLDWC-
-TRNNITNYIYLAEYDNKLLLNIKNKLHLS-IIFQEFSKLKM-NDRLSLFECEED-----
---IFVSSN---KRFEECVFS-FRQTDRKKIT------FTN-----SLNRNYQYINDMNR
VKLLG---SDWISLRVNYVDSRVEEFLSCGYKEFYKHNKDINKIEK--GFFVRYA-----
DPT--P-HLRIRFKLSK--N---EKYNTFLGNITEWLTNEREKG--LVNDFHFVSYNPEI
ERYG--NFLIDKAEDIFSIDSLIVADSFE-------------GDVPLNRELFCCLNIMSI
LKG-FNLNFAS-----QLEILNMA-IDPKMYKEAYRENKANLDPIITN----IYDYIEIP
MSEKL-------IIPTTFND----------------------RDNVI---RKYAELI---
DANEDVLTNVKSDIIASILHMHCNRLNG-INRDLENKILGMCYHTIKKYMNLIKYKYNVL
V-------------
>DQ146939.1|c1|7381-10356|+|ABA00879.1|NsuB
--------------------------------------------MKNRYIANNFLVRNTI
T--------ETHELLECDYNS------------------------------FLETIRENK
IFQEQLFVASRSLYESLQKYYSGDSM------KRKKINQLSESVYKYYKRSKERSTPFGL
FSETSIGSFSSTEKLNLNGKTL-----KKVLLDSE-WLIRLVFKIEKEYS--RELAYKIN
SANYQFGDRVVQLF---------SINDTKTEEVNIKFTKVYQLIYELCCD-KYVYFNCII
EKLVE-SYGEEYRDIATSYIMSLIDSHFLISNINSELIINFKFEEFISKV-----KEIDK
QN--------L----YYFKLIAISNLIVEY---SELEIGDGIEKLQEIYMLMSS------
------LVE--TP------NFLQIDLYN---DAQI------------QLGNENKTQ-IVE
FTEFLVSNTDH-----VKRTYLDDYKEKFLEKYGVNREVQLIELFDSNLGVGS-PY-GYQ
HPKNDFWESAPSTIYFNEK------------------------EELEYLNKFEKALETG-
GNIQLYNG-----EDFFSQAKDKIN-------VGFELFFYVSKVN-------------GK
SVLNLTNTGCSKYLGASSGRFSILSDKLEHYHRSITHIVE---KNNQASGYHSCEITFLP
ENLRHANVMRTTNVREKVLS-LFTNM-------DE-----RSQILSDIYIGIDS-KN--S
FYARSF-KTGEFLKFYSTNMYNQ---MMFCNELRFLSEIS-----QEDHFGIFPWEMVYQ
KFS---HIPRILFK-DIIVAPERWRLSGKM--------------------LSKDINQII-
-LENNLPIKFYVDNSDNRILINRNNPLDNQ-LFEDIVRKNSNKNEELCLSECIFD-----
---SHLVEKGTTTYVSDIVVPVFVKDEFKE--------PRC-----IKEILPEVIPTNVR
QKIPF---DEWLYFKLYMSADRQEEFLSDIMPQILNFVNLDDGM----SFYIRYT-----
DPK--F-HIRLRIR-----T---RNLYKSFEKIQEIFQLCIQNK--LISNIDISTYDREI
ERYGG-LERIPLVEEIFCLDTEIVINSLSLIR---------QKKLDLSPYDLAIIFNYFY
LKSFFKDNNKE-----IIQFLEFACPEHLDSQNRNKNRNTALIDLYL-----IKGYLI--
------------NLLPELSK----------------------LCRSL---KKLSDSC---
---IHLSDDYTYHIYDSIIHVHNNRLFG-IKRENETKIYAIIRGLIISEEYRNRHNHG--
--------------
>AB362350.1|c1|453-3434|+|BAG71480.1|lantibiotic_dehydratase
-------------------------------------------MIQNSFKAQPFLVRNTI
L-----SVKDKQSFTEYTQVI--------------------------------ETANNNK
VFLEQLLIANPKLYDTLQKYNAGLL-------KKKRVKKLFESVYKYYKRSYLRSTPFGL
FSETSIGTFSENSKSELNGETT-----KGVILDTQ-WLIRLVHQMERDFS--RKLSFVIN
NANYEFGDRIFQVY---------TINSSDLEEVNIKSTNVYQIISKTCES-GFQKYEEIC
ESVTA-SYGDEYRELSEQYINSLIVNHYLVSNLQKDILSDFSWETFLNKV-----EEIDD
SK--------K----YLIPLKRVQKLIQEY---SELEIGEGLEKLKEIYQEMSQ------
------ILA--ND------NYIQIDLFS---DSEI------------TFDTEQKQQ-LER
LADFIGNTTKS-----VNRTYLDDYKDKFIEKYGVDQEVQIVELFDSTFGIGA-PY-NYT
HPQNDFYELEPNTAYFSEE------------------------EREKYLSKYVEAIKNN-
EAINFEDL---ESHYQKIAAEKNSK------LQGLELFLDLAKKD-------------EK
DIFVLGNIIGNNNLGGASGRFSALSPELKNYHKSIVDSIEK--ENESKGI-TSCEIVFLP
ENIRHANVMHTSIERKRVLP-VFTST-------SH-----DEVQLTNIYIGIDD--N-EE
FYARDI-STQEVLKFYVTSMYNK---TLFSNELRFLYEIS-----LDDNFGNLPWELIYR
DFD---YVPRLVFG-DIVVSPAKWKIREED--MK----------------TEEITKEFL-
-QSKGVPKEFYIVNGDNKVYLSQENLLDMS-MLEAQIKKSAKRNDFVELQEYIED-----
---GDVVSKRQKGRVSDVVVP-FVRKTTPD--------NDS-----KKFTREKRVSVEQR
EKLPF---TDWLYIKLYISTNRQDEFLLSYLPEIQEIIENLGGQ----LFFLRYT-----
DPQ--P-HIRLRIK-----C---SNLFLAYNSILEILKKSRENR--VMSTFDISTYDQEV
ERYGG-FETLELSEQIFCADSKTIPTLLTVT---K------EANNDWSVDDVSILMDYRY
LKWFFQNDNQE-----ILKFLHLV-SPEKVEENVNEKIVH------------YHNLLETD
NLDGRI------FSDKNFED----------------------LKRTV---EALFYKM---
-VSQNYDTQKVYSIIDSIIHVHNNRLIG-INRDKEKVIYYGLQRLFTSEEYMK-------
--------------
>Z18947.1|c1|520-3501|+|CAA79468.1|NisB_protein
-------------------------------------------MIKSSFKAQPFLVRNTI
L-----SPNDKRSFTEYTQVI--------------------------------ETVSKNK
VFLEQLLLANPKLYNVMQKYNAGLL-------KKKRVKKLFESIYKYYKRSYLRSTPFGL
FSETSIGVFSKSSQYKLMGKTT-----KGIRLDTQ-WLIRLVHKMEVDFS--KKLSFTRN
NANYKFGDRVFQVY---------TINSSELEEVNIKYTNVYQIISEFCEN-DYQKYEDIC
ETVTL-CYGDEYRELSEQYLGSLIVNHYLISNLQKDLLSDFSWDTFLTKV-----EAIDE
DK--------K----YIIPLKKVQKFIQEY---SEIEIGEGIEKLKEIYQEMSQ------
------ILE--ND------NYIQIDLIS---DSEI------------NFDVKQKQQ-LEH
LAEFLGNTTKS-----VRRTYLDDYKDKFIEKYGVDQEVQITELFDSTFGIGA-PY-NYN
HPRNDFYESEPSTLYYSEE------------------------EREKYLSMYVEAVKNH-
NVINLDDL---ESHYQKMDLEKKSE------LQGLELFLNLAKEY-------------EK
DIFILGDIVGNNNLGGASGRFSALSPELTSYHRTIVDSVER--ENENKEI-TSCEIVFLP
ENIRHANVMHTSIMRRKVLP-FFTST-------SH-----NEVQLTNIYIGIDE-KE--K
FYARDI-STQEVLKFYITSMYNK---TLFSNELRFLYEIS-----LDDKFGNLPWELIYR
DFD---YIPRLVFD-EIVISPAKWKIWGRD--------------------VNNKMTIREL
IQSKEIPKEFYIVNGDNKVYLSQENPLDME-ILESAIKKSSKRKDFIELQEYFED-----
---ENIINKGQKGRVADVVVP-FIRTRALG--------NEG-----RAFIREKRVSVERR
EKLPF---NEWLYLKLYISINRQNEFLLSYLPDIQKIVANLGGK----LFFLRYT-----
DPK--P-HIRLRIK-----C---SDLFLAYGSILEILKRSQKNR--IMSTFDISIYDQEV
ERYGG-FDTLELSEAIFCADSKIIPNLLTLIK---------DTNNDWKVDDVSILVNYLY
LKCFFQNDNKK-----ILNFLNLV-SPKKVKENVNEKIEHYL------------KLLKVD
NLGDQI------FYDKNFKE----------------------LKHAI---KNLFLKM---
-IAQDFELQKVYSIIDSIIHVHNNRLIG-IERDKEKLIYYTLQRLFVSEEYMK-------
--------------
>L16226.1|c1|455-3436|+|AAA25190.1|
-------------------------------------------MIKSSFKAQPFLVRNTI
L-----SPNDKRSFTEYTQVI--------------------------------ETVSKNK
VFLEQLLLANPKLYDVMQKYNAGLL-------KKKRVKKLFESIYKYYKRSYLRSTPFGL
FSETSIGVFSKSSQYKLMGKTT-----KGIRLDTQ-WLIRLVHKMEVDFS--KKLSFTRN
NANYKFGDRVFQVY---------TINSSELEEVNIKYTNVYQIISEFCEN-DYQKYEDIC
ETVTL-CYGDEYRELSEQYLGSLIVNHYLISNLQKDLLSDFSWNTFLTKV-----EAIDE
DK--------K----YIIPLKKVQKFIQEY---SEIEIGEGIEKLKEIYQEMSQ------
------ILE--ND------NYIQIDLIS---DSEI------------NFDVKQKQQ-LEH
LAEFLGNTTKS-----VRRTYLDDYKDKFIEKYGVDQEVQITELFDSTFGIGA-PY-NYN
HPRNDFYESEPSTLYYSEE------------------------EREKYLSMYVEAVKNH-
NVINLDDL---ESHYQKMDLEKKSE------LQGLELFLNLAKEY-------------EK
DIFILGDIVGNNNLGGASGRFSALSPELTSYHRTIVDSVER--ENENKEI-TSCEIVFLP
ENIRHANVMHTSIMRRKVLP-FFTST-------SH-----NEVLLTNIYIGIDE-KE--K
FYARDI-STQEVLKFYITSMYNK---TLFSNELRFLYEIS-----LDDKFGNLPWELIYR
DFD---YIPRLVFD-EIVISPAKWKIWGRD--------------------VNSKMTIREL
IQSKEIPKEFYIVNGDNKVYLSQENPLDME-ILESAIKKSSKRKDFIELQEYFED-----
---ENIINKGEKGRVADVVVP-FIRTRALG--------NEG-----RAFIREKRVSVERR
EKLPF---NEWLYLKLYISINRQNEFLLSYLPDIQKIVANLGGN----LFFLRYT-----
DPK--P-HIRLRIK-----C---SDLFLAYGSILEILKRSRKNR--IMSTFDISIYDQEV
ERYGG-FDTLELSEAIFCADSKIIPNLLTLIK---------DTNNDWKVDDVSILVNYLY
LKCFFQNDNKK-----ILNFLNLV-SPKKVKENVNEKIEHYL------------KLLKVN
NLGDQI------FYDKNFKE----------------------LKHAI---KNLFLKM---
-IAQDFELQKVYSIIDSIIHVHNNRLIG-IERDKEKLIYYTLQRLFVSEEYMK-------
--------------
>X68307.1|c1|1439-4420|+|CAA48381.1|
-------------------------------------------MIKSSFKAQPFLVRNTI
L-----CPNDKRSFTEYTQVI--------------------------------ETVSKNK
VFLEQLLLANPKLYDVMQKYNAGLL-------KKKRVKKLFESIYKYYKRSYLRSTPFGL
FSETSIGVFSKSSQYKLMGKTT-----KGIRLDTQ-WLIRLVHKMEVDFS--KKLSFTRN
NANYKFGDRVFQVY---------TINSSELEEVNIKYTNVYQIISEFCEN-DYQKYEDIC
ETVTL-CYGDEYRELSEQYLGSLIVNHYLISNLQKDLLSDFSWNTFLTKV-----EAIDE
DK--------K----YIIPLKKVQKFIQEY---SEIEIGEGIEKLKEIYQEMSQ------
------ILE--ND------NYIQIDLIS---DSEI------------NFDVKQKQQ-LEH
LAEFLGNTTKS-----VRRTYLDDYKDKFIEKYGVDQEVQITELFDSTFGIGA-PY-NYN
HPRNDFYESEPSTLYYSEE------------------------EREKYLSMYVEAVKNH-
NVINLDDL---ESHYQKMDLEKKSE------LQGLELFLNLAKEY-------------EK
DIFILGDIVGNNNLGGASGRFSALSPELTSYHRTIVDSVER--ENENKEI-TSCEIVFLP
ENIRHANVMHTSIMRRKVLP-FFTST-------SH-----NEVLLTNIYIGIDE-KE--K
FYARDI-STQEVLKFYITSMYNK---TLFSNELRFLYEIS-----LDDKFGNLPWELIYR
DFD---YIPRLVFD-EIVISPAKWKIWGRD--------------------VNSKMTIREL
IQSKEIPKEFYIVNGDNKVYLSQKNPLDME-ILESAIKKSSKRKDFIELQEYFED-----
---ENIINKGEKGRVADVVVP-FIRTRALG--------NEG-----RAFIREKRVSVERR
EKLPF---NEWLYLKLYISINRQNEFLLSYLPDIQKIVANLGGN----LFFLRYT-----
DPK--P-HIRLRIK-----C---SDLFLAYGSILEILKRSRKNR--IMSTFDISIYDQEV
ERYGG-FDTLELSEAIFCADSKIIPNLLTLIK---------DTNNDWKVDDVSILVNYLY
LKCFFQNDNKK-----ILNFLNLV-STKKVKENVNEKIEHYL------------KLLKVN
NLGDQI------FYDKNFKE----------------------LKHAI---KNLFLKM---
-IAQDFELQKVYSIIDSIIHVHNNRLIG-IERDKEKLIYYTLQRLFVSEEYMK-------
--------------
>NC_008022.1|c2|879924-882890|+|YP_598531.1|serine/threoninedehydratase
----------------------------------------------MYKVFPTGMIRIPL
Q---------KQEFYNKDYED----------------------------------LINDK
VFMEQLLVASPSLYDSVIDFDKC---------NEKKKQNVKVSLNSYSKRAAFRTTPFGI
FTAINTVDLTKGTTSNVQKVSFI----KKAVPDYS-WIYSLVKSYEISN--LEKLSLKIN
TAAFTQGDRYVLP----------FTVNESEEDRNISFSKPIKLLVEKCKT-RYIKYEELI
DVFKN-NYPDIVSDMLESYIHDLVTNDFLISDLRPPICNINSLDYLLSKL--------EE
GT-------------LCTDLTTLKKMIEDY---NDLNIGEGRDLLLQIFDKMES------
------IYKYDNG-----GNYLKVDSLA---EYEGGF----------NILSETARESIEL
LAEMFVKLNTNVKRRGGRKNSLEEYQLKFIGKYGENCSIPFVEVINKDAGIGF-PE-YYK
GGEGEAIELSDP-------------------------------IMQMFEKKYEEALLNG-
GHIEFYSK---DLDDFQTDQSNSLD--------SFELNFNIKIIN-------------ND
VKLYLGANIGSGQAGRSFGRFYGLSETVRETI-----------KNLNHQNNTNVELSFVP
KQIRLANVIQNYSDESYNTS-FFTTS-------WDSE---NELRLEDIYIRYSD--G--K
FHFTTI-DGKNELKFTMNNMLNS---DSQSRVLRLLVDLSEFE-YGLSHWSLFPWDILAQ
ERV---YIPEILFE-DITIATAQWNLSVIR--------EEIIHQKIFTG-KKDIFNKFR-
-KTYKIPKDIILKYADNELRLDLSIDSDLE-ILFKNIN--K--YRFVSLRGIEQG-----
---ESIFKDNLGNYNTEIVVPILKESNGIN----------------NTNDNVQFKNEVKK
IYLPF---CDWLFFKFYGPKERQEELLNNWKKFWLNLPSELFSQSN--MFYMRYN-----
DTN--D-HIRIRINCDSI-E---NNFSLYLSVVQDLLPQLIESC--IISDIEVSSYKPEV
NRYGG-PHLISYAEEIFCKESILFLNNT-------------IEFSDDERLVCATYLVLYY
LNH-FFKDKET-----RRSFLFEN--YTGKYKKDFKNLPIDLP---------IEYMKSLN
GVTSAL------DRYDFFQE----------------------MDRYL---MSYMKEY-NR
FGGTNDIYNTKFNLVGSFLHLSMNRLNG-IDREFEEKVYCFAYYTLNAQQYIEWE-----
--------------
>NC_007296.1|c2|807523-810489|+|YP_280252.1|serine_(threonine)_dehydratase
----------------------------------------------MYKVFPTGMIRIPL
Q---------KQEFYNKDYED----------------------------------LINDK
VFMEQLLVASPSLYDSVIDFDKC---------NEKKKQNVKVSLNSYSKRAAFRTTPFGI
FTAINTVDLTKGTTSNVQKVSFI----KKAVPDYS-WIYSLVKSYEISN--LEKLSLKIN
TAAFTQGDRYVLP----------FTVNESEEDRNISFSKPIKLLVEKCKT-RYIKYEELI
DVFKN-NYPDIVSDMLESYIHDLVTNDFLISDLRPPICNINSLDYLLSKL--------EE
GT-------------LCTDLTTLKKMIEDY---NDLNIGEGRDLLLQIFDKMES------
------IYKYDNG-----GNYLKVDSLA---EYEGGF----------NILSETARESIER
LAEMFVKLNTNVKRRGGRKNSLEEYQLKFIGKYGENCSIPFVEVINKDAGIGF-PE-YYK
GGEGEAIELSDP-------------------------------IMQMFEKKYEEALLNG-
GHIEFYSK---DLDDFQTDQSNSLD--------SFELNFNIKIIN-------------ND
VKLYLGANIGSGQAGRSFGRFYGLSETVRETI-----------KNLNHQNNTNVELSFVP
KQIRLANVIQNYSDESYNTS-FFTTS-------WDSE---NELRLEDIYIRYSD--G--K
FHFTTI-DGKNELKFTMNNMLNS---DSQSRVLRLLVDLSEFE-YGLSHWSLFPWDILAQ
ERV---YIPEILFE-DITITTAQWNLSAIR--------EEIIHQKIFTG-KKDIFNKFR-
-KTYKIPKDIILKYADNELRLDLSIDSDLE-ILFKNIN--K--YRFVSLRGIEQG-----
---ESIFKDNLGNYNTEIVVPILKESNGIN----------------NTNDNVQFKNEVKK
IYLPF---CDWLFFKFYGPKERQEELLNNWKKFWLNLPSELFSQSN--MFYMRYN-----
DTN--D-HIRIRINCDSI-E---NNFSLYLSVVQDLLPQLIESC--IISDIEVSSYKPEV
NRYGG-PHLISYAEEIFCKESILFLNNT-------------IEFSDDERLVCATYLVLYY
LNH-FFKDKET-----RRSFLFEN--YTGKYKKDFKNLPIDLP---------IEYMKILN
GVTSAL------DRYDFFQE----------------------MDRYL---MSYMKEY-NR
FGGTNDIYNTKFNLVGSFLHLSMNRLNG-IDREFEEKVYCFAYYTLNAQQYIEWE-----
--------------
>NC_008021.1|c2|888967-891933|+|YP_596657.1|serine/threonine_dehydratase
----------------------------------------------MYKVFPTGMIRIPL
Q-----KQEFYNKDYED--------------------------------------LINDK
VFMEQLLVASPSLYDSVIDFDKC---------NEKKKQNVKVSLNSYSKRAAFRTTPFGI
FTAINTVDLTKGTTSNVQK-VSFI---KKAVPDYS-WIYSLVKSYEISN--LEKLSLKIN
TAAFTQGDRYVLP----------FTVNESEEDRNISFSKPIKLLVEKCKT-RYIKYEELI
DVFKN-NYPDIVSDMLESYIHDLVTNDFLISDLRPPICNINSLDYLLSKL---------E
EG--------T----LCTDLTTLKKMIEDY---NDLNIGEGRDLLLQIFDKMES------
------IYKYDNG-----GNYLKVDSLA---EYEGGF----------NILSETARESIER
LAEMFVKLNTNVKRRGGRKNSLEEYQLKFIGKYGENCSIPFVKVINKDAGIGF-PE-YYK
GGEGEAIELSDP-------------------------------IMQMFEKKYEEALLNG-
GHIEFYSK---DLDDFQTDQSNSLD--------SFELNFNIKIIN-------------ND
VKLYLGANIGSGQAGRSFGRFYGLSETVRETI-----------KNLNHQNNTNVELSFVP
KQIRLANVIQNYSDESYNTS-FFTTS-------WDSE---NELRLEDIYIRYSD--G--K
FHFTTI-DGKNELKFTMNNMLNS---DSQSRVLRLLVDLSEFE-YGLSHWSLFPWDILAQ
ERV---YIPEILFE-DITITTAQWNLSAIR--------EEIIHQKIFTG-KKDIFNKFR-
-KTYKIPKDIILKYADNELRLDLSIDSDLE-ILFKNIN--K--YRFVSLRGIEQG-----
---ESIFKDNLGNYNTEIVVPILKESN-----------GIN-----NTNDNVQFKNEVKK
IYLPF---CDWLFFKFYGPKERQEELLNNWKKFWLNLPSELFSQSN--MFYMRYN-----
DTN--D-HIRIRINCDSI-E---NNFSLYLSVVQDLLPQLIESC--IISDIEVSSYKPEV
NRYGG-PHLISYAEEIFCKESILFLNNT-------------IEFSDDERLVCATYLVLYY
LNH-FFKDKET-----RRSFLFEN--YTGKYKKDFKNLPIDLP---------IEYMKILN
GVTSAL------DRYDFFQE----------------------MDRYL---MSYMKEY-NR
FGGTNDIYNTKFNLVGSFLHLSMNRLNG-IDREFEEKVYCFAYYTLNAQQYIEWE-----
--------------
>NZ_ACZE01000025.1|c1|26880-29915|+|ZP_06299367.1|hypothetical_protein
------------------------------------------MNEPLFIPASFFLLRVPF
W-----SIDELESMHLEDN-------W---------------------INAVLSKFDNDE
LFREAISIASHSLYQALQKR------------PLKNPTQVCRSLQNYINRMASRATPFGL
FSFVTAGYWDEETRGSLDL-TKVY---RRARPDME-WIYALVKKFYRENSDFSALLVQSN
SLVDLKGDRLFLKYFRFIK----DKKIQTPKTISLYANRLVITIFEMAKS--RLSIDQLW
EKLLE-VLPNLNKEKTFEVIKKLLSHQILLPGILPSLLSDSPFKELMKFL----------
----------P----NAVWMNELETKLSDY---QSTSLGSGELSLQNLRKSMDA------
------VVP--IQ------SPLHVDA-----SYKGT---------PIYLSNEILLK-LQQ
AVTFLWKISAS---RSSQFTSLEAYRKKFIEKFGLHRIVPLKELLSEEKGLGS-FL-AYP
QIDEKSVFYKFSQQ-----------------------------WEKCLNKKWQESMLNHQ
KEIVLTEEWLNSLFELVEEELPDPC----KALSSFDLFFKIQAQSIEEINR-------GN
YQLYL--SDCTWSGGSTFGRFWDLFNPEIQHELSKLAKAE---KHLEKSA-KVVEVSYWP
SHVRNANVSVHPCLREYSLE-IDNKD-------N------SILGLEDLYIGTTH--E--R
FYITLK-DGKEEILARSGNVLSY---IQAPESIRLIREIT--L-SRHLLLYPFYWAGLEE
KAV---FLPRVRMG-LCILSPAKWNLDASS-----------FLKDSLDI-IKVKFLAWA-
-EQWKLPDRFLMTEGDQHLLLTSKHPAHLN-EIATRLK--R--GESLQLMEEITS-----
---EWLKSE-SGSHSGEFVVPFIKNSIYP---------YPE-----NTRTPQAFETVKSR
WMLPG---SQWMYIKVYLSEEQENNFLLNKFIPFIEHLNEFISIND--WFFVRYQ-----
DPE--R-HLRFRLRIED--I---HYYGLILSWLHPIGIQWMEQG--LIKKIMLDSYEREV
ERYGG-EDVMDAVESLFCVDSLAVTSLLKY----F------EKKEDTLETVCHILSIVSF
LNG-FGLDLQT-----KIDVLGNA-RQDQKLLKGFREYKNQLLKLIPALEDPNQPEEGIC
S-----------VVNKFAMI----------------------RIPAQ---NQFLSKA---
---QHIENSRLLEIYSHMIHMHCNRL-G-CDNSQETRLRLFCEHALKCCLKTSHIS----
--------------
>NC_003923.1|c3|1914156-1917149|-|NP_646581.1|hypothetical_protein
-------------------------------------------MNTIYEPSSICMIRTPL
L-----SVEFFNLFLNTEQIK-------------------------------YSDLQLNA
QMKESILTTTFNLYCTLQEINFDG--------DNKKVRDAKESLLKYLIRMSTRPTPFGL
LSGINLGHFVNEPTRLKVG-NSIQ---KYVKVDGE-WLYKLVSYIESIDEYYQNLKVIWN
SKAHIINDRIYLNEQSAI-----YLNNNKDTSFSIKNSELLVFIKTTVTN-NNITFSNLA
EKINQ-EFEINDITKVKVYIHNLVSKEIIYSTIRPPLSYSDNLNYILNKL-----SLHND
----------D----FVKKIREIQKLILAY---EKTEIGFGEELYKDIIHHMKA------
------LFK--CK------NYLQIDTKI---DMINN-----------YLHQDIATN-ISE
AAYLLWLLSRN----NIGFTDLKVLHNRFIEKYGFEQLVNIKDLISDITGFGT----TIF
QEEETDGN-----------------------------------NIVMLKQKFLHALRNN-
DEIVINEK---DVESLINDNEINHY----HAPMSADVYAELYLGRFYNQ---------YN
ELIVISPLTASFNAGATFGRFHHLIDTETLAKLEHEKGHYYQKMICDDNV-EMISINNIP
KYPRNHNVLTNHDSYEYSLN-LGSSN-------SYSK---YELTLDDIYVGATF--N--K
LYLYSS-QLNKRVLFESNNMYNF---LKECNLYRLLREIT--M-ESVKCIEPMNDV-SID
SFS---YSPRIRYK-NVILKPAYWKINEMVLPLP-----------KNEE-WDQQFLKYQ-
-EQFNIPNIVNLVYGDNKLLLNLSLANHRY-LLMKEYK--K--HKRVRLVESFLP-----
--------QSKNDHVYEIVTP-IYK-------------KSS-----YRGPEIEIPKYKNT
DIEYD---KDWFALHIHIDKPSQDTFIIDNLYPFVKHLKDKGDIEK--YFLMRYI-----
KQG--D-ILKLRLFRN---D---ENYAEIYSILKNWLPHVRQTT--EVSDYEFVSYEPEF
FRYGG-KNTINEIEAFFEYDTNLAVNIIE-------------NDFKFDRPYIVAISIMYL
FEM-FSISNEE-----RMEIVNNY-VPTSFKSKDIRPFKNELVTICNP----ANNFEYMA
KHYS--------GIYRILKD----------------------GNQIL---SKLNEGL---
---KKTLTTKRSRIIGSLIHMRCNRIFG-IDKDQETFVLSIVKEIVKTQKHWCGDKND--
--------------
>NC_007622.1|c3|1826308-1829301|-|YP_417145.1|hypothetical_protein
-------------------------------------------MNTIYEPSSICMIRTPL
L-----SVEFFNLFFNTEQIK-------------------------------YSDLQLNA
QMKESILTTTFNLYRTLQEINFDG--------DNKKVRDAKESLLKYLIRMSTRPTPFGL
LSGINLGHFVNEPTRLKVG-NSIQ---KYVKVDGE-WLYKLISYIESIDEYYQNVKVIWN
SKAHIINDRIYLNEQSAI-----YLNNNKDTSFSIKNSELLVFIKITVTN-NNITFSNLA
EKINQ-EFEIHDISKVKAYIHNLVSKEIIYSTIRPPLSNNDNLNYILTKL-----SLHND
----------N----FVKKIREIQKLILAY---EKTEIGFGEKLYKDIIQHMKA------
------LFK--CK------NYLQIDTKI---DMINN-----------QLHQDIATN-ISE
AAYLLWLLSRN----NIGFTDLKVLHNRFIEKYGFEQLVNVKDLLSDITGFGT----SIY
NEVKGDEN-----------------------------------NIVMLKQKFLHALRNN-
DEIVINEK---DVETLINDNEINHY----HAPMSADVYAEIYLGRFYNQ---------HN
ELIVISPITVSLNAGATFGRFHHLIDTETLAKLEHEKAHYYQKSMHDDNV-EFVSINNIP
KYPRNHNVLTNHDSYEYSLN-LGSSN-------SDSK---YELTLDDIYVGATF--N--K
LYLYSS-QLNKRVLFESNNMYNF---LKESNLYRLLREIS--M-ESVKCIEPMNDV-SID
SFS---YSPRIRYK-NVILKPAYWKINEMLLPLP-----------KNEE-WDQQFLKYQ-
-EQFNIPNIVNLVYGDNKLLLNLSLANHRY-LLMKEYK--K--HKRVRLVESFLP-----
--------QSKNDHVYEIVTP-IYK-------------KSS-----YRGPEIEIPKYKNT
DIEYD---KGWFALHIHIDKPSQDTFIIDNLYPFVKHLKDKGDIDQ--YFLMRYI-----
KQG--D-ILKLRLYRN---D---ENYNVIYSILKDWLSFIRQTT--EVSDFEIVSYEPEF
FRYGG-KNTIDEIESFFEYDSNLAVNIID-------------NDFKFERPFIVAISIMYL
FEM-LSISNEE-----RMEIVNNY-VPTSYKSKEIRPFKNELVTICNP----ENNFENIA
KHYS--------DIYRILKD----------------------DDQIL---SKLNKGL---
---KQPLATKRSRIIGSLIHMRCNRIFG-VDKDQERFVLSIVKEIVKTQKYWCGDKND--
--------------
>NZ_GG730175.1|c1|642638-645631|-|ZP_06324838.1|hypothetical_protein
-------------------------------------------MNTIYEPSSICMIRTPL
L-----SVEFFNLFLNTEQIK-------------------------------YSDLQLNA
QMKESILTTTFNLYRTLQEINFDG--------DNKKVRDAKESLLKYLIRMSTRPTPFGL
LSGINLGHFVNEPTRLKVG-NSIQ---KYVKVDGE-WLYKLISYIESNDEYYQNLEVIWN
NKAHIVNDRIYLNEQSAI-----YLNNNKDTSFSIKNSELLVFIKTTVTN-NNITFSNLA
EKINQ-EFEINDITKVKVYIHNLVSKEIIYSTIRPPLSNSDNLNYILNKL-----SLHND
----------D----FVEKIREIQKLISAY---EKTEIGFGEKLYKDIVQHMKA------
------LFK--CK------NYLQIDTKI---DMINN-----------QLHQDIATN-ISE
AAYLLWLLSRN----NIGFTDLKVLHNRFIEKYGFEQLVNVKDLLSDITGFGT-SI--YN
EVKGDKN------------------------------------NIVMLKQKFLHALRNN-
DEIVINEK---DVESLINDNEINNY----HAPMSADVYAEIYLGRFYNQ---------YN
ELIVISPLTVSLNVGATFGRFHHLIDTETLAKLEHEKGQYFQKSMHDDNV-EFVSINNVP
KYPRNHNVLTNHDSYEYSMN-LGSSY-------SDSK---YELNLDDIYVGATF--N--K
LYLYSR-QLNKRVLFESNNMYNF---LKESNLYRLLREIS--M-ESVKCIEPMNDV-SID
SFS---YSPRIRYK-NVILKPAYWKINEMVLPLP-----------KNEE-WDQQFLKYQ-
-EQFNIPNIVNLVYGDNKLLLNLSIANHRY-LLMKEYK--K--HKRIRLVESFLP-----
--------QSNNDHVYEIVTP-IYK-------------KSS-----YRGPEIEIPKYNNT
DIEYD---KEWFAIHIYIEKSSQDTFIIDNLYPFVKHLKGKGDIDQ--YFLMRYI-----
KQG--D-ILKLRLYRN---D---ENYNEIYSILKDWLSFVRQTT--EVSDYEFVSYEPEF
FRYGG-KNTIDEIESFFEYDTNLAVNIID-------------NDFKFERPFVVAISIMYL
FEM-LSISNEE-----RMEIVNNY-VPTSFKSKEIRPYKNELVTICNP----ENNFENIA
KHYS--------DIYRILKD----------------------DNQIL---SKLNERL---
---KQPLTTKRSRIIGSLIHMRCNRIFG-VDKDQETFVLSIVKEIVKTQKYWCGDKND--
--------------
>NZ_GG730342.1|c1|1332001-1334994|-|ZP_06343790.1|lantibiotic_epidermin_biosynthesis_protein_EpiB
-------------------------------------------MNTIYEPSSICMIRTPL
L-----SVEFFNLFLNTEQIK-------------------------------YSDLQLNA
QMKESILTTTFNLYRTLQEINFDG--------DNKKVRDAKESLLKYLIRMSTRPTPFGL
LSGINLGHFVNEPTRLKVG-NSIQ---KYVKVDGE-WLYKLISYIESNDEYYQNLEVIWN
NKAHIVNDRIYLNEQSAI-----YLNNNKDTSFSIKNSELLVFIKTTVTN-NNITFSNLA
EKINQ-EFEINDITKVKVYIHNLVSKEIIYSTIRPPLSNSDNLNYILNKL-----SLHND
----------D----FVEKIREIQKLISAY---EKTEIGFGEKLYKDIVQHMKA------
------LFK--CK------NYLQIDTKI---DMINN-----------QLHQDIATN-ISE
AAYLLWLLSRN----NIGFTDLKVLHNRFIEKYGFEQLVNVKDLLSDITGFGT-SI--YN
EVKGDKN------------------------------------NIVMLKQKFLHALRNN-
DEIVINEK---DVESLINDNEINNY----HAPMSADVYAEIYLGRFYNQ---------YN
ELIVISPLTVSLNVGATFGRFHHLIDTEILAKLEHEKGQYFQKSMHDDNV-EFVSINNVP
KYPRNHNVLTNHDSYEYSMN-LGSSY-------SDSK---YELNLGDIYVGATF--N--K
LYLYSR-QLNKRVLFESNNMYNF---LKESNLYRLLREIS--M-ESVKCIEPMNDV-SID
SFS---YSPRIRYK-NVILKPAYWKINEMVLTLP-----------KNEE-WDQQFLKYQ-
-EQFNIPNIVNLVYGDNKLLLNLSIANHRY-LLMKEYK--K--HKRIRLVESFLP-----
--------QSNNDHVYEIVTP-IYK-------------KSS-----YRGPEIEIPKYNNT
DIEYD---KEWFAIHIYIEKSSQDTFIIDNLYPFVKHLKGKGDIDQ--YFLMRYI-----
KQG--D-ILKLRLYRN---D---ENYNEIYSILKDWLSFVRQTT--EVSDYEFVSYEPEF
FRYGG-KNTIDEIESFFEYDTNLAVNIID-------------NDFKFERPFVVAISIMYL
FEM-LSISNEE-----RMEIVNNY-VPTSFKSKEIRPYKNELVTICNP----ENNFENIA
KHYS--------DIYRILKD----------------------DNQIL---SKLNERL---
---KQPLTTKRSRIIGSLIHMRCNRIFG-VDKDQETFVLSIVKEIVKTQKYWCGDKND--
--------------
>NZ_ACFR01000008.1|c1|94937-97918|-|ZP_03613908.1|epidermin_biosynthesis_protein_EpiB
-------------------------------------------MKSIFNTSSYYIIRAPL
L-----PVSIYNTYLKNDEID-------------------------------YSSFFQNK
IIEETILTTTYHLYQSLTNISFDS--------EKKKARNAKESFLKYLIRMSTRGTPYGL
LSGVSLGQLAEKTNIQIQEDVNYYY--KSVKIDGS-WLSKLIHFLESNYDYYQDSYVIWN
ERNYITDQRIYLDNQTC------LIQENNKELVSIKNNDLLKFIKQSLQE--DLTFKDLI
KLISE-KFLINDEQEIKSFIQNLLDKEIIFTSLRTALKKENPLDYLLCFY-----RDFDN
----------D----FIRSLQLIHFEMMKY---QFMEIGKGKKTFLRIRELMSH------
------LFK--AK------EYIQIDTKI---QTKNN-----------YLSKKIARN-ISE
AAYLLWLLSPD----DLGISTNHDFHYSFLEKYGLEQIVNLKELLSDINGMGY----CTK
EDKSIKN------------------------------------NSPFLKEKYYYALSHN-
EEIEITEN---DFLDIEKKNTIPIE----RAPLSSEIYSEFYYGNIING---------YD
EFLVISPIVSSFNAGATMGRFSQEIDRDIRKQLDNEIYEQYIEYSNENNT-EVIHINEIP
KYARNLNINHSGTIKFKELD-LDMPC--------------SSIALDDLYVGSTF--D--K
LYLFSK-TLNSRILFITHSMLNY---VLCSNLYRFLREVS--L-GNTKFIQPIKDD-GIE
GFN---YCPRIRYK-NVILKPATWKLNKDM-----------FSSSEKEN-WIEQFHKIQ-
-QFYNIPNDVTMAFGDNRLTINLSNDAHIS-ILKKEIE--K--QGRVCLLE---------
---DFISKS-NNDRVIEIVTP-IYR-------------KAK-----SNEKRITIPKNIYK
RLETK---REWLSIHLYIDESYQNEFLIQYILPCLRELFDNNHLES--FFFIKYR-----
END--H-FIKLRLLSK---S---NDSIHLYHEMMQLKQKWLKES--ELSTYAIVDYQPEI
NRYGG-IETIEIIEDYFMYDSWLAIYIID-------------QTFNYPKEFIVAITIIFL
INE-LNISQEE-----IDEIRHNN-VENLYRNNEIREYKNEMVKLTNP----RDNYCYLH
AKLP--------KLHQILYN----------------------NYKEI---EKLKVAL---
---SRGLSTPRAHIIGSLIHMRCNRVFG-VNRDKEKFVLSIFNEIEKTKKYWCGDIINE-
--------------
>X62386.1|c1|1605-4565|+|CAA44253.1|
-------------------------------------------MDNIFVPSNIYMVRTPI
F-----SIELYNQFLKSDNID-------------------------------YDLILQND
IFKESIMTTTYNLYQSIGKIDWEK--------DNKKTRNVKESLLKYLIRMSTRSTPYGM
LSGVALGEFSENNNIKIKDSSFHK---KDVKIDGQ-WLYKLVHYLESDYTYYKDSFVIWN
QQNYIYNNRLYLDNNSS------ITENKRNDVLSVKYNSILVFIHENSKK--NITYEELV
QLISS-KYSIENKEEVKVFVQELINKEIIFSDLRPTLENKNPLDYIINSL--------NP
KN--------S----LVGTLINISNEITKY--SKMPL-GKGEYKYLDIVNLMSQ------
------LFV--SK------NYLQIDTYI---DYSRN-----------ELKQSLADN-ISE
AAYILWLLSPN----HFGTKTIRNYHEFFMDKYGFEQLVNLKQLLSDINGFGY-PK-KDS
YSFSN--------------------------------------NIAFLKEKYLLAIQNN-
SHIEITEN---DVKNLEKNNTVSKI----NAPVSTEIYSEIY--FGNSIKG-------YE
DFAVISPILGSFNAGATFGRFTGNFNIKKKNQLQKEIVHHYNNYMNENGL-EISQLNEGP
LNSRNVNILNNNRIYNTCLN-LNLPK--------------SDIDINDIFIGATF--N--K
LYLYSE-KHDSRIVFVSNSMFNYE--F-GSELYKFLREIS--F-EKTKFIQPITEE-GID
SLP---FCPRIIYK-NIILKPATWKINSEM-------------FSETEN-WLNRFATIR-
-EKWHIPKDVIIAFGDNRLLLNLLNDKHLI-ILKKELK--K--HGRIRILE---------
---SFINES-NNERMLEIVTP-LYK-------------KTS-----LKEQSFIIPKNRNK
HFNNL---KDWFSIHLSIPKTYQDNFIQDYLLPFITELKVNNFINK--FFYIKFK-----
EDE--D-FIKLRLLRE---D---EDYSQIYSFIKNWKDYCLLNS--ELYDYSIVDYVPEV
YRYGG-PHVIEDIENFFMYDSLLSINIIQ-------------SEFKIPKEFIVAISIDFL
LDY-LEINKSE-----KEEILINN-AEDLYRSNDIREYKNLLAKLTNP----KNDYEILK
KEFP--------NLHEFLFN----------------------KISIL---ENLKKTL---
---QKSLYTSRSRIIGSFIHMRCNRIFG-INPEKEKFVLSIFNEITKTKKYWDGCD----
--------------
>DQ367437.1|c1|5949-8876|+|ABC94903.1|GdmB
------------------------------------------------------MLRTPL
F-----SIETYKHHLNSNDIN-------------------------------YNLLLKNG
IIKESIMTTTYNLYKSISKIDFEK--------NNKKARNAKESILKYLIRMSTRSTPYGM
LSGVALGEFTENNNIKIKDPSCHK---KDVKVDGQ-WLYQLVHHLESDYTYYKDSIVIWN
QQNYIYNNRLYLDNNSS------ITKNKDNDALSVKYNTILMFIHEKSYE--NITYKELI
HLISN-EFNVENKEDVKLFIQELINKEILFSNLRPGLENKNPLDYIIKNL-----NSKD-
----------S----LVESLINTSNEIKKY---SKIPLGEGESNYLYIINLMSK------
------LFD--SK------NYLQIDTYV---DYSKN-----------ELKKSLANN-ISE
AAYVLWLLSPN----HFGTKTIRNYHEFFMDKYGFEQLVNVKQLLSDINGFGY-PQ-KAN
YSFSN--------------------------------------NIAFLKEKYLLAIQNH-
SHIEITET---DIKKLEKNNTASET----DAPVSTEIYSEIYFGNLIDG---------YD
EYAVISPILGSFNSGATFGRFTGAFDTKKRNQLEEEIVQRYNHYMNENDL-KISQLNEAP
LNSRNVNILNNNKIFDTSLN-LNLPK--------------SDVDINDIFVGATF--N--K
LYLYSE-KYNSRILFISNSMFNYE--F-GSELYKFLREVS--F-EKTKFIQPITEE-SID
TLP---FCPRIIYK-NIILKPATWKLNLEM-------------FSESKD-WINTFTTIR-
-KKWGIPENVIIAFGDNRLLLNLLNDKHLV-ILKKELK--K--HGRIRILE---------
---SYINKS-DNKRMLEIVTP-LYK-------------KTH-----LKEKHFIIPKNRNK
NFHSL---RDWFSIHLSIPKTYQDNFIRDYLFPFITELKVNKHINE--FFYIKFK-----
KDE--D-FIKLRLFRE---D---EDYSQIYPFIKKWKDYCLLNS--ELNDYSIVDYIPEV
YRYGG-PHVIENVEKFFMYDSLLSINIIQ-------------TEFEFSKEFIVAMSIEFL
IEQ-LNISDSE-----KKEILINN-AEDLYRNNEIREYKNLLAKLTNS----KNNYQFLK
EEIP--------KLHEFLFN----------------------KISIL---EILKHTL---
---QENLYTSRSRIIGSFIHMRCNRIFG-INPEKEKFVLSIFNEITKTKKYWDGRD----
--------------
>NZ_ACMO01000117.1|c1|248863-251952|+|ZP_04205873.1|hypothetical_protein
-------------------------------------MEVSIMKNGTFAIGDTVTVRSPL
F-------SANVNVIGEKKYS---------------------------YADILDLFSNP-
IIREAILTTNLAFYNIIKN-------------NKGNKEQIINTFSNYLQRMSIRATPLAL
LSSVSLQNINNLHKLETNDLSQLK---KHTRIDMD-WLFEFTKHLEDNWDILLFLDVKIN
NTIFKTSNYVNNIYLSYYGKKYEDIKKNGSTTLSLKNTQILEYIIDSCKT--FTNFNKLF
KDLKEISIGVVEPPVIFSFLRKLINDEILITNLRPCIGSNSIFEDIIDVL-----KAIPT
AE--------L----YYKKLLYIQKLLNEY---DNSIIGEGEEIYLKIVNTLKK------
------IVE--SK------NYLQVDTTF---SPKN------------TEAIKIELNDLNS
LAHFLYKTNIK----DIESVSLKEYKNKFVEKYGTECEIPLLELIDKNRGLGY-PE-SYD
IYDKNNPQYNN--------------------------------LKQYVTDKIINCYLNEN
NEISLIDE---EIEQLNLNQNESNI-------LNFELNFMINNDFNKN----------TN
YAFSLMPNIGSMRANKMAGRFLNYFNSTDKDNLKLMIDEEKNFFDSQNS--LLTELTYFP
EKSRIANISQTNSFLDYELP-IATTS-------NKNPS--STIELNDIVVGLSL-ES--K
FYLKSS-KLNKQIICTNSHMMNPN--I-CHSLYQFLYKIN----PLPKSFTLLQVISEIK
NSQI--YTPRITYK-SIILSPKTWNIPSNY-----------LIDSDIHA-LHSSILKIK-
-KDYKIPNQVYLLIGDNRILININNFHEMH-KIKKHLK--K--YSSVSLTEIE-------
---PFLLNSKKNLKIHEIVIP-FSREDKEN--------IKL-----PKISIQTNKSYIAK
KYNPL---GKWSYIKLYTSEYKQNELLIKYINPFIERLQKEGIIEK--FFFIKYL-----
DPN--P-HIRLRILW----S---KSSPNRFDLLNDFLEFLQNKE--IIFSTDICSYTPEV
IRYGG-PNAIEAAETYFYHDSKFISQILDV----T------KLQPELDLSIISVITLHHF
LSC-FNFTLSE-----QNKLLSNN-TSHKLFRKDYRNSRKLLMHLSND----NNNWMNLR
ENKKYC------FLYELLIQ----------------------REEGI---INYRKTL-DL
LINNGTLSNNLENIVFSCIHMYCNRLYG-TNRESEQKVVTLTSHTINDLSHFKSNVSLV-
--------------
>NZ_ACPD01000003.1|c1|53261-56395|-|ZP_04803878.1|Lantibiotic_dehydratase_domain_protein
------------------------------------------MDNKLYKASDFFMLRCPS
L-----PIGDYVDSLANVDDM---------------------------YQWVLKKFNEDN
ILREIILVSSSSLYEALEK-------------KQGDKEKIVSSFLKYYIRITTRPTPFGL
SSGITIGEFDEIDNISKISFKGNNPRVKRARVDSS-WLLKLVRKLEMNKDILQKLRVKVS
GTLLEKGSRIENKIVTQYG----QEDKDGNFSTTIKYSGAVKAVLYLAKE--YINFNELM
MKFVE-NTSEIGEESIYKFLLELIEKEYLITDLRPIFNISNPLGYVCKKL-----IDIGV
AE--------------GNEIKELEDSIDEY---NKTEVGEGQILYKNIICSMEK------
------ICR--ND------QYLQVDMRISEKEC--------------VISTEVLNE-IES
FGEILGTFGCR----YLEKSYLKSYKGEFIERYSEGQEVPLLELTDESMGIGY-PA-TYS
KPSNKKVLQDEVSVNEDK-------------------------ITKFFAMKMMNFSSIKS
KEVIITKE---EIEKLNLNKSKIND-----LPTSFELNFLLNQNNDESS---------EG
YDLVLGANIGSGRIGKTFGRFMDLFNESEVNRIKEEVDRDT--ESLSKEI-IYAQISSIH
PIEKCSNVVSNFNFLDYELP-IGVNS-------SKDEE--YKLSLDDLVVGMRN--G--K
FYLKSR-KKNKEVVFYSHDMLNY---TITYNIYRLLLELS----NDNQSLTLIDTLLMSR
QKFW--YVPRIKFN-NIILFPQTWLLSFDM-----------LDITTSDKNFEEKFYNWA-
-EENELVRYIYLGTGDNRLVLDIEKKEHVR-IIFQELK--KSSEQKVRLQEVIGG-----
ISSGITID--NKRYCAEIVVPIIRKAYDEYKQENI---VPK-----LIDQEKSYEYSEER
VFLPF---DEWIYLKLYGDKNREDEIIGNYINPFVKELYDKKLIKK--MFFIRYS-----
DEK--P-HIRLRLKCV---E---EKELELYKEIKDFLNKMYNEK--LLFKVTQDTYFREV
ERYGG-IEIFDEAEDIFNVDSIIVSELLKFKN---------RKMITIDSKNIAAINIVKL
MDD-FGFSYEE-----QLKYFDKL-IEQKEYRKEFSKIRKELMKICNS----DNYWKGLR
ETEEGE------LIYNIISM----------------------REDSI---KKYRVKL-EQ
LNLEGKLTNTVDNIIGGIIHMFCNRFFG-INRGLERESLALARHTLYSLKYFKNAVNG--
--------------
>NC_007772.1|c1|56697-59777|-|YP_473415.1|putative_SpaB_protein
-------------------------------------------MKQLFKDVGSFMIRTPS
L-----PIDLLVDNVENSDNI----DN---------------------IMFLSDSSFYKN
QFNEAILVASHDLYESIQRYINGD--------KVRNMDYLLNSVYKYFSRSCSRCTPFGL
FSTVSFGDITFKKTSFELRETELK---RKPLIDSN-WLFEVVYMYEDRY--LKSLKYKIN
EGVAVYRNKANLFNCTQ------NNNSEKINKKSVNYSKAFEIVLEIAND--YVSYYEII
ENLKK-SYPNMDEGIFHTYIHSLIKEDYLISDLRPPLTISNQLEYFISKL-----IEYDI
NS---------------DIFIDIKKQIDIY---SDESKDEKINCLMNIFNNMKS------
------VYN--SK------NYLAIDSSF---DYKEC-----------NLNVNEIKN-IDK
LINLFIQFNVN-----DPFDILKEYKDKFLGKYGLSRCVSLIELIDNDIGLGF-PS-HYD
RKTNVNNFGGYINP-----------------------------WVKFFERKYIESIRIN-
SEIEITDT---DIRMLLSENFEKDR-----LPKTMEIYFNYIKEN-------------GK
DVFQLSNIFGSTYAGKSFGRFSHFMDEPKSFYEKINKA-----YGNDDEC-QFCEFAFLP
DSLYTANVIRNMNGSKYEIS-FGTSN-------SKDNI--YKLKLSDILVGFEN--N--K
LYLKSA-INNKRIVPTSTNMFNP---QLKPKILRLIDDIS----SDGIRFYNKPWQNLLE
KFA---YIPTIRYK-NFILEQEKWIFKIDDLGLA--------KRYNFNE-FKKGFNEYT-
-KSRNIPSWVYIVDADKKLLLNLKDDRCLS-VLQKSLE-----KSEIILERYNED---VE
HPVKYNGSS----YCCELVIP-LMLDGEGY--------SSK-----SNDTKFAQICSNDR
IKEPL---DEWLYFKIYGVEENIDYLLGEALFIPLQELLKNKEIDS--YFFIQYK-----
DPD--T-HLRLRLKAD---K---DRLIAVQPKMFDIFSKLMKQS--IIFKYSIDCYELEL
ERYGG-YDLMDYAHEVFHKDSIVIQSIIREK---N------NRNTEISDELLALIIIFFH
MIK-FKLSLEE-----MYIFLECD-NNTKNNKEEFKKNRDKYVEFAIN----YLTGKKVT
LEEE--------FILDILSA----------------------KNESM---EIYLNKI---
KESYLNDRTVKLSILDSLLHMSMNRLFG-PNTDLERKMRNLARHTFYSIYNRNKKTGILD
GKKNEKI-------
>NZ_ABDX01000039.1|c1|11577-14666|-|ZP_02640727.1|putative_SpaB_protein
----------------------------------------MKKMKQLFKDVGSFMIRTPS
L-----PIDLLVDNVENSDNI----DN---------------------IMFLSDSSFYKN
QFNEAILVASHDLYESIQRYINGD--------KVRNMDYLLNSVYKYFSRSCSRCTPFGL
FSTVSFGDITFKKTSFELRETELK---RKPLIDSN-WLFEVVYMYEDRY--LKSLKYKIN
EGVAVYRNKANLFNCTQ------NNNSEKINKKSVNYSKAFEIVLEIAND--YVSYYEII
ENLKK-SYPNMDEGIFHTYIHSLIKEDYLISDLRPPLTISNQLEYFISKL-----IEYDI
NS---------------DIFIDIKKQIDIY---SDESKDEKINCLMNIFNNMKS------
------VYN--SK------NYLAIDSSF---DYKEC-----------NLNVNEIKN-IDK
LINLFIQFNVN-----DPFDILKEYKDKFLGKYGLSRCVSLIELIDNDIGLGF-PS-HYD
RKTNVNNFGGYINP-----------------------------WVKFFERKYIESIRIN-
SEIEITDT---DIRMLLSENFEKDR-----LPKTMEIYFNYIKEN-------------GK
DVFQLSNIFGSTYAGKSFGRFSHFMDEPKSFYEKINKA-----YGNDDEC-QFCEFAFLP
DSLYTANVIRNMNGSKYEIS-FGTSN-------SKDNI--YKLKLSDILVGFEN--N--K
LYLKSA-INNKRIVPTSTNMFNP---QLKPKILRLIDDIS----SDGIRFYNKPWQNLLE
KFA---YIPTIRYK-NFILEQEKWIFKIDDLGLA--------KRYNFNE-FKKGFNEYT-
-KSRNIPSWVYIVDADKKLLLNLKDDRCLS-VLQKSLE-----KSEIILERYNED---VE
HPVKYNGSS----YCCELVIP-LMLDGEGY--------SSK-----SNDTKFAQICSNDR
IKEPL---DEWLYFKIYGVEENIDYLLGEALFIPLQELLKNKEIDS--YFFIQYK-----
DPD--T-HLRLRLKAD---K---DRLIAVQPKMFDIFSKLMKQS--IIFKYSIDCYELEL
ERYGG-YDLMDYAHEVFHKDSIVIQSIIREK---N------NRNTEISDELLALIIIFFH
MIK-FKLSLEE-----MYIFLECD-NNTKNNKEEFKKNRDKYVEFAIN----YLTGKKVT
LEEE--------FILDILSA----------------------KNESM---EIYLNKI---
KESYLNDRTVKLSILDSLLHMSMNRLFG-PNTDLERKMRNLARHTFYSIYNRNKKTGILD
GKKNEKI-------
>NC_006582.1|c4|3703005-3706154|-|YP_177053.1|lantibiotic_biosynthesis_protein
---------------------------------------MRKSEQLLYEPVDTIMLRAPI
L-----SLSHDHQNASKDDII----------------------------PILKEYIERP-
EIKEALAVASPNLFQSLDKIHGDP--------RSKKTRNAVSSLLKFLIRMSSRPTPFGL
FSGIAIGELGNKTVGSLLDTKQHQ---KRARPDME-WLLGVVSKIEKNQTIAKKLNVVFN
DAVYQTDDRVYLHYFSNCGQLRSSENQERKDNISIRKTVVVEFVQSVAKK--PISISELI
NQLQL-TYTSASINEIESFVWNLFQQEFLISELRPPIVNCAPLSYVIQIL-----ESIPE
AT--------E----IGAMLKGIEADIETY---NQLPIGQGLDFFQTLTAKMQD------
------IHP--SK------QPLQVDLRL---TCAEKV----------RINRSIGEQ-VAN
AAEWLWRLSKN----ETGVAHLREYHVEFLEKYGVNREIPLLDLLSDEKGLGA-PP-TYK
YPPSAKSVNPPQMKS----------------------------THRLLMEKYIQCLRENA
KEITLTES---DLQKLMDNDTDDVF-----APNSGELFVEVLASSAEEVDK-------GN
YQLAIGTNVGSQELGQTFGRFSDMIASEENRNLMEEQKKIE--ETCTDVETEYVELSFLP
QSGRASNVSITHSTRNLHTT-IATNA-------NGQN---KKLLLEDILVGATL--G--R
FYLKSK-KSNKRLVFTSNNMFNY---ESAPNCFRFLREVS--L-EDGKAIQGVNLG-SLR
EFT---FIPRITSG-KVILSPAIWKLNDQIEELS-------DFSMPLEE-WIEQFSTWM-
-KKMQVPEQVFMAYGDNRLYIHLKNANHMQ-ELRSELR--R--RGRVQLQEIIGG----Y
REKQWVKSP-LGRHNAEFIVPFKKRPHVPA--------KPT-----VMIKPVAEVPIECR
EKEPG---TDWLYFKLYGPIHKQQKLISTQIPTLVAELENHKLINS--WFFIRYY-----
DSE--P-HLRLRFHGDP--K---TLLAGALPVFQKWYAAQRLAG--NVKKVVIEPYEREI
ERYGG-LSLMPLMERYFEKDSLLTSNLLGLS---S------KQALKEPLELIASMYVVYF
LTE-YGWHHER-----QLEWISKW-SEDPAYSKEFRPYRNDVLKWLDQ----EENWKALK
EQKG--------FLFKLFSK----------------------NEAII---HELSHNM---
--EITPMTNTEERVVGSLIHMHCNRLLG-TDRDREKKAMAFVRQIIESQKHWNKTKGRPL
NV------------
>NC_014023.1|c1|134234-137512|-|YP_003565953.1|Lantibiotic_dehydratase
-------MLFPLFSSFELYYKRKGRLTLILQKEKFNHKSSVTTENNLFEPLPFFMLRAPF
L-----PTHTFDQLKDEAVLV----------------------------EKLRAYAEKD-
YVKEAIAIASPSLLNSLHYIHGDL--------NNRKTQQVLSSMLRYMLRMTTRPTPFGA
FSGVAAGQFKKNSSLKIDHFKEFK---KRARPDME-WLLGVISVLERSN-ILPSLIVDKN
RASYVVGDRLHLPFSTECGQLR-KKGMEKRENISIIYSEVVEKVLNLAEE--RITVREIT
QRLHT-IYPNTDVTIIQRFIIQLLEQEYLITELRPPLTIDNPFNYLIRKL-----EEKDE
KI--------E----LYEELLKVRELINTY---NQLPLGEGLSLYSDLISQMRH------
------IYE--VT------TPLQVDFSL---NATDL-----------TIGEKVGED-ISK
AAQILWSIADE----GVGFPHLQKYHVDFLEKYGTSREVPLLELLSEELGLGA-PA-SYQ
NPHGKRGGDTTTSSINQE-------------------------RNSQLSYLLIKAIHNQE
KEIEITEE---IAQRMSKEKDRRYA------PDSLEVYGELHAASQEDLDQ-------GN
YTFCLSPNPGSNALGSTFGRFLDILDPDVSLKIQQYQQKID--LEFNEDT-VMVEGSFLP
ATGRSANVAIGKTTRKVNVT-LGTNG-------DEET---IQLPIDDIVVGASL--E--N
FYMKSK-KLGKRIKVVAGNMLNY---QSAPNIYRFMREIS--L-NDLDQWRPFNWG-SMA
HSP---YYPRIRYK-NIVLSPSIWKLNKEVFGMR-------EKPQNEEE-FFKAFGEWR-
-EKWSVPRNVFMTYGDNRILIDLENTLHLR-ELKNELF--K--QGRLQLRETLQD-----
-RDQNCLNSPLGRHAVEIVVP-LKKTENTERRKK----IGA-----IGEAKKDIVSNKII
YKLPG---SEWLYVKLYAPNARENDLILKYLTPFASEMVKSDMASS--WFFMRYR-----
DTD--E-HIRLRFQGDP--S---KLSGLVLPRLREWADKLMDLG--LLQKITIDTYEREV
ERYGG-PMLIEKAEDYFHYDSQSVAMILST----L------NQQNHLPAYVMASLSIIDI
MDN-FGLNYAQ-----QVASIENN-TEKYEYIDEFRPLRKELSLIGDS----RNDWENLR
NYNSGVGK----SIYESFLI----------------------RKESL---TRYVTEI-KE
LQKRDMLWNEHQMIMGAIIHMYCNRLLG-ANRELEKKALAFTRHILSSQKYWRNKNEEYA
RSYNGK--------
>NZ_ACMT01000391.1|c1|184-3399|+|ZP_04178050.1|Lantibiotic_biosynthesis_protein
---------------------------MITEKRKTIHTSNKTACNNIFEPLPFFMIRSPF
L-----PFNALYQIKDQELLI----------------------------EKLREYAEMD-
YIKEAIAIASPSLLESLKYIHGDL--------SNRKTQQVISSVLRYMLRMTTRPTPFGA
FSGVASGEFKEKSLLEMSHFEQFK---KRTRPDME-WLLGVVSSLEKNPCILQFLMVSKN
HATYRVGNRLYLPFSTECGQLR-KKDMEKKENISITYSEVVKKVLDLAET--HITVKELL
QKLNN-DYPGTDIKVMENFILQLVEQEYLITELRPPLTYDSPFDYVIDKL----KVRVGE
NQ-------------IWEDLLKVKDLILVY---DQLQLGKGLSIYNDLILLMKG------
------IYE--VS------TPLQVDFAL---NMHDL-----------AIGKNVAND-VSK
AAQVLWSIADS----GVGFPHLQKYHIEFLEKYGTTREVPLVELLSEELGLGA-PA-TYK
NPKGNRDGENFTPPLDEE-------------------------RNVQLSYMLIEAIHNQQ
KEIEITDE---IISRIGIEKDTRYA------PDSFEVYGELYATSQKELDN-------GK
YNLCLSPNPGSHAAGSTFGRFLDILDPNVRREIQQQEVEID--HQFNNDV-VMVEGSFLP
ATGRSANVAIGKTTREVTVT-LGTNG-------DEDT---LQIPIDDIVVGASL--E--N
FYLKSK-KLGKRIKVVAGNVLNY---QSGPNIYRFMREVS--L-NDLDHWRTFNWG-NMT
SSP---YYPRIRYK-NIILSPAIWKLNRETIGMK-------NKPKSDDE-FLILFEKWR-
-VKWAVPRYVFMTYSDNRILIDLENILHLR-ELKNELF--K--QGRLQLRESLHD-----
-INKNCLSSPLGSHAMEVVFP-LKKMNDVAKRKS----LGA-----VEDGKKEMVSEKMI
YRLPG---SEWLYVKLYVPQARENEFISKYMTSFANNIVQNGLAQS--WFFMRYR-----
DPD--A-HIRLRFYGDP--K---KLNASVLTHLRDWANNLMNSG--FIHKMTIDTYEREV
ERYGG-PYLIELAENFFHYDSRSVTMLLNVI----------GQQAELPVHALASLNIIEI
MEN-FGLTYEQ-----QLETIERN-TDKYEFMDEFRPMRKLLSNIGNP----EGDWNNLR
NYNSSIGL----EIYKSLLV----------------------RRESL---KEYVSSI-KQ
YKNEDKLWNKQQTIMGAIIHMHCNRLLG-ANRELEKKALAFTRHILSSQRYWRNQNETDT
QSHT----------
>NZ_ACMU01000131.1|c1|5819-9034|+|ZP_04172085.1|Lantibiotic_biosynthesis_protein
---------------------------MITEKRKTIHTSNKTACNNIFEPLPFFMIRSPF
L-----PFNALYQIKDQELLI----------------------------EKLREYAEMD-
YIKEAIAIASPSLLESLKYIHGDL--------SNRKTQQVISSVLRYMLRMTTRPTPFGA
FSGVASGEFKEKSLLEMSHFEQFK---KRTRPDME-WLLGVVSSLEKNPCILQFLMVSKN
HATYRVGNRLYLPFSTECGQLR-KKDMEKKENISITYSEVVKKVLDLAET--HITVKELL
QKLNN-DYPGTDIKVMENFILQLVEQEYLITELRPPLTYDSPFDYVIDKL-----KVRVG
ED--------Q----IWEDLLKVKDLILVY---DQLQLGKGLSIYNDLILLMKG------
------IYE--VS------TPLQVDFAL---NMHDL-----------AIGKNVAND-VSK
AAQVLWSIADS----GVGFPHLQKYHIEFLEKYGTTREVPLVELLSEELGLGA-PA-TYK
NPKGNRDGENFTPPLDEE-------------------------RNVQLSYMLIEAIHNQQ
KEIEITDE---IISRIGIEKDTRYA------PDSFEVYGELYATSQEELDN-------GK
YNLCLSPNPGSHAAGSTFGRFLDILDPNVRREIQQQEAEID--HQFNNDI-VMVEGSFLP
ATGRSANVAIGKTTREVTVT-LGTNG-------DEDT---LQIPIDDIVVGASL--E--N
FYLKSK-KFGKRIKVVAGNVLNY---QSGPNIYRFMREVS--L-NDLDHWRTFNWG-NMT
SSP---YYPRIRYK-NIILSPAIWKLNRETIGMK-------NKPKSDDE-FLILFEKWR-
-VKWAVPRYVFMTYSDNRILIDLENILHLR-ELKNELF--K--QGRLQLRESLHD-----
INKNCLSSP-LGSHAMEVVFP-LKKMNDVAKRKS----LGA-----VEDGKKEMVSEKMI
YRLPG---SEWLYVKLYVPQARENEFISKYMTSFANNIVQNGLAQS--WFFMRYR-----
DPD--A-HIRLRFYGDP--K---KLNASVLTHLRDWANNLMNSG--FIHKMTIDTYEREI
ERYGG-PYLIELAENFFHYDSRSVTMLLNV----I------GQQAELPVHALASLNIIEI
MEN-FGLTYEQ-----QLETIERN-TDKYEFMDEFRPMRKLLNNIGNP----EGDWNNLR
NYNSSIGL----EIYKSLLV----------------------RRESL---KEYFSSI-QK
YKNEDKLWNKQQTIMGAIIHMHCNRLLG-ANRELEKKALAFTRHILSSQRYWRNQNETDT
QSHT----------
>NZ_GG692670.1|c1|420180-423008|+|ZP_05578969.1|SpaB
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MVSYINRSATRTTPFGL
FSGVGLADTTNNQLSNLNKEKTKFI--KHARIDLE-WLINFVKYIEKNY--YLNLNFQFN
SSLYIVGDRVFLP----------YNTDSKTDKISINLNRPFEMIYRKFRQADFFSFETLI
GYLQA-EYPERDTKVLQSFLNTLIEKEFLISSLRPPLTNVDELDWVISKM-----NDIPD
TQ--------I----YKNLLVEIQNDISAY---RKTEIGDGITLYESILSKMKS------
------IKEIKSK------SYLQVDCEI---KTNSL-----------VLIKEDMNQ-LED
FASFLLEISKY-----QKNKYLDEFKLRFLERYGEYIEVPIYELLDETLGIGA-PM-NYS
QPQNRYITPFENLTEKSD-------------------------LTEYFMDKYIQSIKMN-
TSITFNFK---EISSYVEQKKNKIV------PKNLELNFIVKEFE-------------NK
KKFYLGPNIGSNKAGKTFGRFAYFSNQFLEVITEFDHQ-----FSELSKE-EICELVYLP
KNIRSGNVTRDSTSTRKNIS-LHTSS-------YDKE---NEIKMTDILVGVEN--D--R
LYLRNL-ADNKKILVTSNNMLNP---TIADNGIRLLQEIS--L-QDELSWSNFPWSEVYS
QFS---YVPQIEYK-NIVIETELWKINKYVLELP-------NDKPTKEQ-FVSNFKEIQ-
-TKLQIPNVFYLQSADNRILVDITKQVYID-LIYKKYN--Q--FGEIIIRGIEAG-----
---ESLNSICDGEKSVEVVIP-FFRASKDS--------EET-----NENTRINNKLHADN
NFAPF---ENWIFYKIYCSNENQEEVIT-FVNYFIEELSTEASIDI--SYFMRYS-----
DPL--P-HIRLRIKAD---K---QYLFEIAERFNRFISPLQHSK--LVSKYIIATYYPEN
ERYGG-QELMPLAEHLFQIDSQVVVKLMA---------------NDQQKEKIGVVSVLHY
LNS-FGIAFEN-----QIKLLEAS-VGKENFSVEFKDIKNEYISSIDS----YNNWYSFK
KDKKNQ------ELIELMAQ----------------------RENAI---QEYAKAL---
-SDSNDLTNYLEDIILSVIHLHCNRLFG-TDREFERKVYFFALHTLKGQSYKRKMMIENE
TSD-----------
>M86869.1|c1|2-1174|+|AAA22837.1|
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LEEIKSP------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------FFEFH----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-RTYELPQTFYIVNADNRLLIDIENDCTLD-VFFWELK-KTNHNQPLQLVAVEHD-----
--ADALMDRNQNDYSGEIVVP-LLRKQPEK--------PLY-----LPVLNAIEGSGSDR
IKMPF---EDWLFIKLYCKQTREEELIAFEIADFYNQISDQYPVR---HFFMRYR-----
DPK--P-HIRLRFNGKA------EVLYSLFPQLLNWLKSLREKG--LVSESVITQYEREI
ERYGG-LSLMEAAEQLFCEDSKVVEMMIRMHR---------MKDITISKEIAGMVSVIQF
LEQ-FELTFEE-----QLTFLERN-SLQNEYRTEFKKDREMYIEICNS----DRDWDNLK
KTSDGG------MLYETLKT----------------------RKMAA---AHYAFLI---
-KKAFDNKDEVYSRIGSIIHLHCNRLFG-TDRELENKILTLCRHSLYAQRYQKMNGSLAW
K-------------
>M83944.1|c1|10-540|+|AAA22769.1|subtilin
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MEAAEQLFCEDSKVVEMMIRMH---R------MKDITISKEIAGMVSVIQF
LEQ-FELTFEE-----QLTFLERN-SLQNEYRTEFKKDREMYIEICNS----DRDWDNLK
KTSDGG------MLYETLKT----------------------RKMAA---AHYAFLI---
-KKAFDNKDEVYSRIGSIIHLHCNRLFG-TDRELENKILTLCRHSLYAQRYQKMNGSLAW
K-------------
>NC_006510.1|c1|324824-326977|+|YP_146153.1|lantibiotic_biosynthesis_protein
------------------------------------------MKDLIFKNIDTFMIRTPV
L-----SVDNYLRFFDQKLTE---GEM---------------------KERLLEICHNP-
VFRESILVASKSLYNKMIDFCNGK--------EIKKYDYFIKAIYKYLIRISTRPTPFGL
FAGVDFGEYTDENTSIRYGTNKYK---KFARPDLE-WLMKIVKKLEQEQ--YEQLWFTVN
DSIFLKGERAYLLHSTR------KDDDKRVNEISVRVTLPFKITCELARH--LIHYQTLK
KELIK-QFPNTSEEKIERFLKQLIENEFLISNLRPPLTVMDQLDYLIKRL------KESH
IE--------E----WSNELIDIQQKIRTY---TMTPLGEGEQIYKELHKKMKK------
------LAD--TK------NVLQVDMKL---NLQEK-----------KLNKQVIKD-VNE
LMHILLPFSMT---YQQTDSPLSRYKQEFIEKYGVDREVPLLEMLDNDLGIGA-PM-DYT
NPKNARLAVGVPHQLIDEQ------------------------LREYFLHKYIEAVKDK-
KSITITED---EIKELGLDDYDYQS-----IPDSLDINVIIKCDSEQDLEH-------NH
FKYYIGPNLGSTHAGKSFGRFSYMMEGEEKLFETLNKEMLN--LNNDSGEYVTCELVYLP
NETRHANVTRNIHNSEYELA-LFTNN-------SKDEY--HRLSLNDILIGIEN--D--M
FYAKSK-TLNKKLIITMNNMLNT---QNAPNAIRFLYDIS--L-DGKKIWCNFPWDTIFQ
DYA---YIPAIEYK-NFVIAPRKWVPSSTV------------------------------
----------------------TRQTKCLSPLDTKGIG----------------------
------------------------------------------------------------
--------GIWAHFG---------------------------------------------
-----------RVSRCE-------------------------------------------
------GGCLESLEEVPALEPQ--------------------------------------
------------------------------------------------------------
------------GIALVWPS----------------------------------------
-----------------------VRFVD--------KGRRFLKKNVQA------------
--------------
>NZ_ABVH01000012.1|c1|49526-52072|-|ZP_03149197.1|Lantibiotic_dehydratase_domain_protein
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MIHYQTLK
KELIK-QFPNTSEEKIERFLKQLIENEFLISNLRPPLTVMDQLDYLIKRL------KESH
IE--------E----WSNELIDIQQKIRTY---TMTPLGEGEQIYKELHKKMKK------
------LAD--TK------NVLQVDMKL---NLQEK-----------KLNKQVIKD-VNE
LMHILLPFSMT---YQQTDSPLSRYKQEFIEKYGVDREVPLLEMLDNDLGIGA-PM-DYT
NPKNARLAVGVPHQLIDEQ------------------------LREYFLHKYIEAVKDK-
KSITITED---EIKELGLDDYDYQS-----IPDSLDINVIVKCDSEQDLEN-------NH
FKYYIGPNLGSTHAGKSFGRFSYMMEGEEKLFETLNKEMLN--LNNDSGEYVTCELVYLP
NETRHANVTRNIHNSEYELA-LFTNN-------SKDEY--HRLSLNDILIGIEN--D--M
FYAKSK-TLNKKLIITMNNMLNT---QNAPNAIRFLYDIS--L-DGKKIWCNFPWDTIFQ
DYA---YIPAIEYK-NFVIAPRKWVINKII---------KTNDKISFTE-FEKRFKKFC-
-SDYNVPKYVYLTFADNRILLNTEDENCLR-ILHHEFN---NRYGNIILSSYEEA-----
-DLHLVKDDDEKEYVCELVIP-LVKVKQENRQW-----YAK-----AKKSNHIPSFSDIR
VKLPF---ENWLYLKLYGVHSRADDFIAFYLSEYCREKLAKGEIEK--YFFIRYA-----
DPE--Q-HIRLRLNAS---E---EKLLQIYPDMKQWLRTLIEKR--VVSRFSIDCYEREI
ERYGG-TELIDLAENLFFFDSIVVEDILKLK---R------LKHIQFSDEVIGMVSIIHY
MEQ-FGLNYES-----QLDFLQQQ-VNKQDYREDFQKNRSVYMKVCNT----DNDWQGLR
DTDEGM------LLLNVLNQ----------------------RNRSI---KEYASKI---
--QDGLEASSELSILDSVIHLHCNRLFG-IDREFEKKIRTLVAHTLYALKYIKAHGLVLK
N-------------
>NC_009328.1|c1|299768-302908|+|YP_001124395.1|SpaB
------------------------------------------MNDLVFKNIDTFMIRTPV
L-----SVDNYLRFFDQKLTE---GEM---------------------KERLLEICHNP-
VFRESILVASKSLYNKMIDFCNGK--------EIKKYDYFIKAIYKYLIRISTRPTPFGL
FAGVDFGEYTDENTSIRYGTNKYK---KFARPDLE-WLMKIIKKLEQEQ--YEQLWFTVN
DSIFLKGERAYLLHSTR------KDDDKRVNEISVRVTLPFKITCELARH--LIHYQTLK
KELIK-QFPNTSEEKIERFLKQLIENEFLISNLRPPLTVMDQLDYLIKRL------KESH
IE--------E----WSNELIDIQQKIRTY---TMTPLGEGEQIYKELHKKMKK------
------LAD--TK------NVLQVDMKL---NLQEK-----------KLNKQVIKD-VNE
LMHILLPFSMT---YQQTDSPLSRYKQEFIEKYGVDREVPLLEMLDNDLGIGA-PM-DYT
NPKNARLAVGVPHQLIDEQ------------------------LREYFLHKYIEAVKDK-
KSITITED---EIKELGLDDYDYQS-----IPDSLDINVIVKCDSEQDLEN-------NH
FKYYIGPNLGSTHAGKSFGRFSYMMEGEEKLFETLNKEMLN--LNNDSGEYVTCELVYLP
NETRHANVTRNIHNSEYELA-LFTNN-------SKDEY--HRLSLNDILIGIEN--D--M
FYAKSK-TLNKKLIITMNNMLNT---QNAPNAIRFLYDIS--L-DGKKIWCNFPWDTIFQ
DYA---YIPAIEYK-NFVIAPRKWVINKII---------KTNDKISFTE-FEKRFKKFC-
-SDYDVPKYVYLTFADNRILLNTEDENCLR-ILHHEFN---NRYGNIILSSYEEA-----
-DLHLVKDDDEKEYVCELVIP-LVKVKQENRQW-----YAK-----AKKSNHIPSFSDIR
VKLPF---ENWLYLKLYGVHSRADDFIAFYLSEYCREKLAKGEIEK--YFFIRYA-----
DPE--Q-HIRLRLNAS---E---EKLLQIYPDMKQWLRTLIEKR--VVSRFSIDCYEREI
ERYGG-TELIDLAENLFFFDSIVVEDILKLK---R------LKHIQFSDEVIGMVSIIHY
MEQ-FGLNYES-----QLDFLQQQ-VNKQDYREDFQKNRSVYMKVCNT----DNDWQGLR
DTDEGM------LLLNVLNQ----------------------RNRSI---KEYASKI---
--QDGLEASSELSILDSVVHLHCNRLFG-IDREFEKKIRTLVAHTLYALKYIKAHGLVLK
N-------------
