>NC_013928.1|c3|1876638-1877654|-|YP_003485696.1|hypothetical_protein
--------------------------------------MEETIKVW--------------
-NNNNVDYIKNKIGVKRRTVVSSDEDTLTLAMEAGQEAV------LHFKEDVAKIDSVLL
GSCTTPDIFKSNANQLMSFLLNKNDYFGCDIRASENSGAASLVLGYSLVSSG--LSNTSL
IFSADTLSKNIFPSE---------LREPYIGSGAASIILGKGEDILA-----------EI
IGIGNSN-ASFP-----EQGRTEDNRYLRVLAN-LNYSVVKEGRI--KRSLESINNALEN
ASLKAEDIKYFVFQ----------DGTEQTY--------------------------KEF
SHFFHFDNVINQDIFKNLGYIGSASPIISMLAALES------------------------
-------------AEVGDIILMCGYGHSSGSTTVIFRVTEEITFKNKIIDK------LKN
YKDINYSEAMKH----E----------FKYSQPEISL-----------------------
GTFI---------------------------
>DQ083928.1|c1|2771-3853|+|AAY86548.1|PhlA
----------------------------------MNKVGIVSYGAGIPVCRLKVDDVIQV
WKNTDLSLVKGQLGVIERAVLQPDEDVITLGVLAAQRAL--------DEAPPCSLEALYL
GTCTNPYDSRASAAIILEMLGCGYDAFCADVQFAGKSGTSALQIAYALVASG--MVGNAL
AVGADTINRNTAPGD---------LTESYAGAGAAALLLGTENVIAHFD--ASFSCAADV
ADNIRPQGDRYIRSGMGLGPDKNSIGLEDQTRRAASGLMAKIHAQ--ADDFDYVVFQQNL
VSTPYSLGKHL----------------------------------------------GFT
KAQIEPGI-YAQSV----GDAGAASPLLGLVNVLDQ------------------------
-------------ARPGERILVVSYG--FGAGSDAIALTVTDAIEAYQKTNVPLRTQLED
KYYVDYRTSIKY-----------------------EFKYLR-------------------
PDYALTAYL----------------------
>NC_011887.1|c2|456058-457248|+|YP_002490385.1|hydroxymethylglutaryl-CoA_synthase
----------------------------------MTGVGIDDISIYTPEYYYSLHDLVIA
-HGIDPNKYLVGIGQERMAVPPPDEDVVSMAANAVAPLL--------TRQLRDTVSTVIF
ATESGIDQSKSAGLFVHGLLGLNPHCRVVEFKQACYSATAGIQLAADLVRQR--PMEKVL
VIASDIARYERGSEG-----------ECTQGAGAVAMVISANPRLLELH-PVSGLYSVDV
MDFWRPNHRSTAC----VDGKLSIDVYLRSLAEAWADYRRKGGLP--LGAVDKLCFHQPF
TRMAKKAFAALSEA-----------AGSEAA--------------------------HLD
ESCYADSQIYGRAI----GNTYSASLYIGLCSLLDR-C----------------------
-----------GEDLGGRTIGLFSYG--SGAVGEFFTATVKPQYRRHLRAE-AHRAMLDS
RRRLDGRTYAAW----F--YD------APSQAEDRVFPQESR------------------
GRFRLAAIEGQRRIYAAASSEPARAAA----
>NZ_DS999533.1|c1|258117-259298|+|ZP_05125440.1|hydroxymethylglutaryl-CoA_synthase
----------------------------MTSGAKNVKVGIDSLSFFVPGAYLELEALAER
-HGVNPDKFEVGLGQKKIALTGFDEDVVTLAAEAALPIL--------DAEGVEGIDTLLF
ATETGIDQSKAAGVYVHRLLNLSPNCRTVELKQACYSATAALQMACGYVSRN--PEKKVL
VVASDVSRYDLDSAA-----------EATQGCGAVAMLVSVSPKLLTLD-PVAGCFTEDI
MDFWRPNYRKTPL----VDGKYSTLRYLNALEQCWKDYQKNGGRA--YGEFVQFCYHLPF
SRMGEKGHRHLAKL-----------ANGEPN-----------------------------
LDRCKASLVYNREV----GNCYAASLYMGLASALEN-T----------------------
-----------EIDLTGKPIGLYSYG--SGAVAEFFAAEVQPGYGDHLLKK-RHKALLDD
RKAVSYDTYLSL----R----AVP---DPQDGSSVEMPRLAR------------------
GRYRLAKIDKHKRHYVNA-----------SS
>AJ431696.1|c1|4687-5853|+|CAD24420.1|HMG-CoA_synthase
-----------------------------MKVPKMTVTGIEAISFYTPQNYVGLDILAAH
-HGIDPEKFSKGIGQEKIALPGHDEDIVTMAAEAALPII--------ERAGTQGIDTVLF
ATESGIDQSKAAAIYLRRLLDLSPNCRCVELKQACYSATAALQMACAHVARK--PDRKVL
VIASDVARYDRESSG-----------EATQGAGAVAILVSADPKVAEIG-TVSGLFTEDI
MDFWRPNHRRTPL----FDGKASTLRYLNALVEAWNDYRANGGHE--FADFAHFCYHVPF
SRMGEKANSHLAKA-----------NKTPVD-----------------------------
MGQVQTGLIYNRQV----GNCYTGSIYLAFASLLEN-A----------------------
-----------QEDLTGALVGLFSYG--SGATGEFFDARIAPGYRDHLFAE-RHRELLQD
RTPVTYDEYVAL---------------WDEIDLTQGAPDKAR------------------
GRFRLAGIEDEKRIYVDRQA-----------
>NC_012985.2|c2|1019338-1020528|-|YP_003065432.1|hydroxymethylglutaryl-coenzyme_A_synthase
-----------------------------------MAIGIEDISFYTTNQYLDLSVIAEK
-YRLDVAKFYVGIGQERMSVLNPDEDIVTMAAAAALPIM--------QNQDKNLIDTLFF
ATESSVDQSKSAAIWLHKLLGLNSSCRVVELKQACYSATCALHMACALVAKS--PERKVL
IVASDVARYDLGSSG-----------EPTQGCGAVAILISSQTSILEIE-DITGIYTNDC
MDFWRPNYRRTAL----VDGKYSTKIYLQSLEAVWHDYQKNKGHD--FNDFQYFCYHQPF
TRMAEKAHIRLSKI----------VHQNLSV--------------------------AEI
EKAIGITTLYNRLI----GNSYTASLYIALISLLDH-S----------------------
-----------SENLAGKRVGFFSYG--SGCVAEFFSGIVQKNYRKKSHQK-RHQHIINS
RIPISYQVYCDL----H----QDI---IPSVEGNCTIPHTTT------------------
GPFRLATIQNHKRIYETT-----NFPDPSCS
>NC_012704.1|c1|37094-38287|+|YP_002905374.1|hydroxymethylglutaryl-CoA_synthase
--------------------------MNAPVNTAVNPIGIHDITFATGHHSFALETLAAK
-HGIDVGKFHKGIGQEVMSQPAADEDIVTMAATAAKRII--------DRNGTDGIRTLLF
ATESGVDQSKSAGVYVHGLLGLPSRVRTIEMKQACYSGVGALQVALGIVARN--PQEKVL
VVASDVARYDLNSGG-----------EPTQGAAAAAFLVQANPGILAVE-PASGVYTYDV
QDFWRPNDRHTAL----VDGKLSIDAYLNAVRGAYDDFIDHGGAD--FAAIDRFCYHQPF
TKMAVKAHMALREH----------VGLSADK--------------------------AET
AAELETTMHYNRMI----GNSYTASVFLALMSLLET-E----------------------
-----------SDNLVGKRVGILSYG--SGAVAEFFTGTIVDGYQKLLHAD-EHKKALDS
REPLTYDAYRDL----H----PGT---RVADITDYDTPEVTD------------------
APFRFAGVKDHSRIYQRR-------------
>NC_006361.1|c8|2386673-2387884|+|YP_118423.1|putative_3-hydroxy-3-methylglutaryl-CoA
--------------------------------MTTTAVGIHDLSFATTHYALDHVLLADR
-LGVDVDKFRLGIGQETMSVAAADEDVVTLAAAAAAPVL--------ERHGAEGIRTVLL
ATESGVDQSKSAGLYLHPLIGLPNSARVVELKQACYGGTAGLQFAAGLIARD--PTQRVL
VIAADVAKYDLDSPG-----------EPTQGAAAVAMLVTADPGIVAIE-TPSGLYSADI
MDFWRPNYRSAAL----VDGKTSVNAYQKAAQEAWSDYRRRGGRD--LGEFAAFCYHQPF
TRMAYKAHRHLLES----------QGHRADP--------------------------DAI
ESAVAHTTHYNRTV----GNSYTASLYLGLMSLLDH------------------------
-----------ADDLSGRPLAFVSYG--SGSVAEFFGGVVVPGYRRHLRTE-TTRAAIAT
REPLGYDEYRAL----H----EAG---TPTDGRYHALPAQTR------------------
RPFRLAAISGHKRIYEAREPLPVTVDQAGAD
>NZ_ACFA01000167.1|c1|41853-43028|-|ZP_05537735.1|putative_3-hydroxy-3-methylglutaryl-CoA
-------------------------------MPGDVSIGIHDLSLATTQYVLTHETLAAH
-NGTGVAKYHRGIGQRAMSVPAADEDIVTMAADAAAPVV--------ARHGADRIRTVVL
ATETSVDQSKAAGIYVHSLLGLSSAARVVELKQACYSGTAALQFAMGLVHRD--PSEQVL
VIASDVSRYELDSPG-----------EATQGAAAVAMLVGADPALLRLE-DRSGMFTADI
MDFWRPNYRTTAL----VDGRESISAYLQAVEGAWKDYTGRGGRK--LDEFGAFCYHQPF
TRMAHKAHRHLLQY----------DGHAVGE--------------------------EEI
TRVIGHTTAYNMEL----GNSYTASMYVGLASLLDH------------------------
-----------ADDLTGQAVGFLSYG--SGSVAEFFAGTVVPGYRARLRSG-AHREAIGR
REEIGYARYREL----H----ERS---FPADGGDHPAPKETT------------------
GPHRLVGLSGHKRIYATR-------------
>AB037907.1|c1|6601-7641|+|BAB07822.1|HMG-CoA_synthase
------------------------------------------------------------
-----------------MSVPAADEDIVTLAATAAAPIV--------ARHGSDRIRTVVL
ATESSIDQAKSAGVYVHSLLGLPSATRVVELKQACYGATAGLQFAIGLVQRD--PAQQVL
VIASDVSKYDLDSPG-----------EATQGAAAVAMLVGADPGLVRIE-DPSGLFTVDV
MDFWRPNYRTTAL----VDGQESIGAYLQAVEGAWKDYSERGGHS--LEQFAAFCYHQPF
TKMAHKAHRHLLNY----------CSHDIHH--------------------------DDV
TRAVGRTTAYNRVI----GNSYTASVYLGLAALLDQ------------------------
-----------ADDLTGERIGFLSYG--SGSVAEFFGGIVVAGYRDRLRTA-ANIEAVSR
RRPIDYAGYREL----H----EWA---FPARRGAHSTPQQTT------------------
GPFRLSGISGHKRLYRAC-------------
>EF397638.1|c1|1-1170|-|ABS50443.1|NapT1
---------------------------------MPDPLGIHDLSFATTEYVLPHTALAAH
-NGTDVAKYHIGIGQESMSVPAADEDIVTMAAAAAAPII--------TRHGSSQIRTVVL
ATESSIDQAKSAGVWVHSLLGLPSATRVVELKQACYGATAALQFAIGLIRRD--PTQHVL
VIASDISKYDADSPG-----------EATQGAAAVAMLVSTNPALATIE-DPSGLFTADV
MDFWRPNYRDTAL----VDGQESINAYLQAVEGTWKDYTEQGGHK--LDEFAAFCYHQPF
TKMAYKAHRHLLNY----------NERDTDK--------------------------HTI
EQALAQTTTYNNVV----GNSYTASVYLALAALLDQ------------------------
-----------ADDLTGRPIGLFSYG--SGSVAEFFAATPTPGYRHHLRTQ-ANRDAITR
RTPLDYPAYLAL----H----EHT---LPTDGGNHHTPTQTT------------------
GPYRLSGLNNHKRIYETR-------------
>GU219978.1|c1|1-1176|-|ADC96649.1|HMG-CoA_synthase
-------------------------------MAADCAIGIHDLSFATTEFVLPHTALAEH
-NGTEIGKYHVGIGQRSMSVPGADEDIVTMGAAAAEPII--------ARHGRGRIRTVVF
ATESSIDQAKSAGVYVHSLLGLPSATRVVELKQACYGATAALQFAVGLVLRD--PAQQVL
VVASDISKYDLESPG-----------EATQGAAAVAMLVCSDPALVRIE-EPSGLFTSDV
MDFWRPNYRDAAL----VDGEGSITAYLQAVESSWKDYTEQGGRS--LDEFTAFCYHQPY
TKMAYKAHRHLLNT----------CAYDTDE--------------------------ARI
SRAVEPTTAYNMVI----GNSYTASTYLGLASLLDR------------------------
-----------ADDLPGRPIGFLSYG--SGSVAEFFAGTVVPGYREHLRTP-AHHEAIGR
RRPLDYAAYREL----H----ERS---FPTDGGDHPTPSQTT------------------
GPYRLAALRGHKRVYERC-------------
>NC_010163.1|c1|215832-216974|+|YP_001620226.1|3-hydroxy-3-methylglutaryl_CoA_synthetase
-----------------------------------MKIGIHKMSFYVPKFYLDINTLAHA
-RGIDPLKYTNGLLTHKMSVAPFNQDIVTLAANATLNYL--------TKEDIKAIDLILF
TTESGIDYSKSAATHLISILGLRNDVRALEMKQACYATTAALYFAKGHILQH--PESKVL
VIASDIAKYGLNSSG-----------EPTQGAGAVSMIVSREPNIMVLE-DQYGIHSEDI
YDFWRPDGLDYAQ----VDGKFSNEMYKKFFLKTFDNYKMQTKHT--LDDFAALTFHIPY
PKIGLRSLELVADK--------------ANN--------------------------PSL
FENFYTSISYNKYI----GNIYTGSLFLSIIALLEQ------------------------
-----------GNLKAGERIGMFGYG--SGAVAEFFSAKLVEGYKAHLNKE-LHEKQLSN
RTELDMEKYAVY----L----------TRKVTNDTVLEDDLD------------------
VKVQLKSITDYKRNYQNN-------------
>NC_008528.1|c2|902165-903334|+|YP_810542.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MEIGIDQISFFTPNLYLDLTELAEK
-RGVDPNKYLVGIGQEKQSIVPPTQDSVSMAANAASILL-----EQKSTEFLNSIDEILF
ASESGIDNSKSGAVYLQKLLNLKKNMRAIEIKQACYGGTFALMTAFDYVKLH--PNKRIL
VVASDIARYGLKSAG-----------EVTQGAGAVAMLVSTQPRLASYN-WDSVFQSEDL
MDFWRPLDQSEAL----VFGKMSQEIYEKFFYEIWQTYSQKNLKK--VSDFAAFVFHLPF
TKMGKKALDQINDQ-----------IDESKK--------------------------DQL
EKNRLAGQIYNRKV----GNLYTGSLYLSLISLLKN------------------------
-----------NILKNNDRIAMFSYG--SGAEGELYSLSLAADYRQAILGD--PAQMIAS
RRKVSVDEYEGL----F-----RA---FPEDSEDHELTNSYDS-----------------
SHFQLKRIKDHQRIYGDNF------------
>NC_010471.1|c2|1015708-1016868|-|YP_001728247.1|3-hydroxy-3-methylglutaryl_CoA_synthase
-----------------------------------MIIGIDKMASYTPEFALDLTTLALA
-RGDEPEKYTIGIGQNKQAVIPNFEDVVTMGVNAARKIL--------TVADREQIDMVIF
ATESGIDNSKSAAIYAQRLLGLSSFSRTIELKQACYAGTYGLMQANDYVKAH--PDKRVL
VIASDIARYGIATPG-----------EVTQGGGAIAMIVSQDPKLLAFN-DDSVYMSQDV
ADFWRPLDRTEAI----VDGHLSTDIYKEMFLTLWQRYKQNTNKT--LNDFAGFAFHLPY
TKMGKKALDQIIDE-----------AHDGQR--------------------------QRL
LANLEASQLFSREV----GNLYTGSVYLSLLSLISN-S----------------------
-----------SDLLPGEQLAIFSYG--SGAEAELYSVTLQKDFHQYVPAD-ETKAMLAQ
RHEVTVAEYETM----F----NAQ---LHHSYGESQTAANSAR-----------------
KTVQFWGWRDGQRIYQ---------------
>NZ_ACKV01000026.1|c1|1540-2697|-|ZP_03913643.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MAIGIDKLSFYTSEYVLDLVELAQR
-RGVDPNKYTIGIGQDKQSVIPNYEDVVTMGANAAAKII--------DNDDRQQIDLIIF
ATESGIDNSKSSALYVQKLLNLSEFSRTIEIKQACYAGTFGLMQARDYVASH--SGKRVL
VIASDIARYGLNTPG-----------EVTQGGGAVAMIVSENPHIATIN-SDSVYMSRDV
ADFWRPIDRTEAI----VDGHLSTDIYKEMFLTLWQRYKDQSGRT--IADFAGFTFHLPY
TKMGKKAFDQIIDE-----------ADEKTQ--------------------------GRL
LKNLKASQKFSREV----GNLYTGSVYLSLLSLLSY-A----------------------
-----------QDLVAGEQLAIFSYG--SGAEAELYSITLQENFFKYVPAN-ETKNELAD
RKKVSVDQYEQI----F----NSQ---LLDSHENVSSDHPDA------------------
DHFQFLGWQNGERQYK---------------
>NC_008531.1|c2|1179963-1181120|-|YP_818655.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MAIGIDKLSFYTSEYVLDLVELAQR
-RGVDPNKYTIGIGQDKQSVIPNYEDVVTMGANAAAKII--------DNDDRQQIDLIIF
ATESGIDNSKSSALYVQKLLNLSEFSRTIEIKQACYAGTFGLMQARDYVASH--SGKRVL
VIASDIARYGLNTPG-----------EVTQGGGAVAMIVSESPHIATIN-SDSVYMSRDV
ADFWRPIDRTEAI----VDGHLSTDIYKEMFLTLWQRYKDQSGRT--IADFAGFTFHLPY
TKMGKKAFDQIIDE-----------ADERTQ--------------------------GRL
LKNLKASQKFSREV----GNLYTGSVYLSLLSLLSY-A----------------------
-----------QDLVAGEQLAIFSYG--SGAEAELYSITLQENFFKYVPAN-ETKNELAD
RKKVSVDQYEQI----F----NSQ---LLDSHENVSSDHPDA------------------
DHFQFLGWQNGERQYK---------------
>NC_013515.1|c1|1413725-1414876|-|YP_003306621.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKIGVEFSDKYLDIKDLAIA
-RNVDVDKFTKGIGQLEMSFTSKNQDIVTLAIKATRDIL--------TEDDKKNIDLVIF
ATESSIDESKAASIYIKNYLGINDYCKCIEIKQACFGATAGLDYAKAHVAMN--PNSKAL
VIAADIAKYGKNTGG-----------EVTQGAGAIAMLVSTNPSIIEFN-NDEIACSEDI
MDFWRPTYSKYAL----VDGKFSVEKYLELLSKSYSGYKNLNN-----TDFSAICLHVPY
TKMAYKGLNSITND-------------------------------------------EKI
LKEFEASVEYNKRV----GNIYTGSLYLSMLSLILN-S----------------------
-----------KNIKVGDKIGMFSYG--SGAVAEFFSVTLVKGYENSIDKE-KIEIKLNN
RKKYSVEEYENM----F--FEDIN---LDENGTAYLGAVD--------------------
DDVYLKEILNHKRIYEVIDYVER--------
>NZ_ACGG01000118.1|c1|17717-18907|+|ZP_03940281.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MTVGIDKIGFYTSPYFIDMVDLAHA
-RNEDPRKYLIGIGQKKQAVIPSTQDVVTMAANAAQKIL--------SEGDKEKIDLVIF
GTETGIDNSKSAAIYVQSLLGISKQARSFEIKQACYGGTAGVQMAVDHIRLH--PESKAL
VLAADIARYGLNTPG-----------EVTQGGGAVAMVISSNPRILEVE-DKRSFHSDNI
MDFWRPLYRHDAV----VDGHYSNSIYVDFFQQTWTDYRQKYHRT--IDDFRALTFHLPY
TKMGLKALRSIIDQ-------------SKHP--------------------------EAI
LEQFEASRMYNALV----GNLYTGSLYLSLISLLSN-S----------------------
-----------EALNQDDLIGLFSYG--SGAQGEFYSGRLSDQFDRSQLKT-DMDTILSE
RSRITIEQYQEM----Y----QTF---LPLNEEDKLFDVSSDN-----------------
SCFVLKGRKENRRIYLTKNGSGDDQSLD---
>NZ_ACGH01000128.1|c1|7589-8779|+|ZP_03943210.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MTVGIDKIGFYTSPYFIDMVDLAHA
-RNEDPKKYLIGIGQKKQAVIPPTQDVVTMAANAAQKIL--------SEGDKEKIDLVIF
GTETGVDNSKSAAIYVQSLLGISKQARSFEIKQACYGGTAGVQMAVDHIRLH--PESKAL
VLAADIARYGLNTPG-----------EVTQGGGAVAMVISSNPRILEVE-DKRSFHSDNI
MDFWRPLYRHDAV----VDGHYSNSIYADFFQQTWMDYRQKYHRT--IDDFRALTFHLPY
TKMGLKALRSIIDQ-------------SKHP--------------------------EAI
LEQFEASRMYNALV----GNLYTGSLYLSLISLLSN-S----------------------
-----------EALNQDDLIGLFSYG--SGAQGEFYSGRLSDQFDRSQLKT-NMDTILSE
RSRITIEQYQEM----Y----QTF---LPLNEEDELFDVSSDN-----------------
SCFVLKGRKENRRIYLTKNGSGDAQSLD---
>NZ_ACGP01000178.1|c1|182014-183204|+|ZP_03954425.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MTVGIDKIGFYTSPYFIDMVDLAHA
-RNEDPKKYLIGIGQKKQAVIPPTQDVVTMAANAAQKIL--------SEGDKEKIDLVIF
GTETGVDNSKSAAIYVQSLLGISKQARSFEIKQACYGGTAGVQMAVDHIRLH--PESKAL
VLAADIARYGLNTPG-----------EVTQGGGAVAMVISSNPRILEVE-DKRSFHSDNI
MDFWRPLYRHDAV----VDGHYSNSIYADFFQQTWMDYRQKYHRT--IDDFRALTFHLPY
TKMGLKALRSIIDQ-------------SKHP--------------------------EAI
LEQFEASRMYNALV----GNLYTGSLYLSLISLLSN-S----------------------
-----------EALNQDDLIGLFSYG--SGAQGEFYSGRLSDQFDRSQLKT-DMDTILSE
RSRITIEQYQEM----Y----QTF---LPLNEEDKLFDVSSDN-----------------
SCFVLKGRKENRRIYLTKNGSGDAQSLD---
>NZ_ACLL01000039.1|c1|88831-89988|+|ZP_05746007.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKMAFATTDKYLDLRELARA
-RNVDPDKYTIGIGQDQQAVVPPTQDIVTLAAAAAQKLL--------TPAAARRISTVIV
ATESGIDNSKAAAIYVKRLLGLSDFVRTVELKEACYSATAGLQFARGIVALN--PQEEVL
VIATDIARYGLNTPG-----------EVTQGAGAVAMLVSRDPRVLAIE-ETSVSLTKDI
MDFWRPLYATEAL----VDGKYSTSVYIDCFKEVLTRYQQLTGRP--LADFGALLFHLPF
TKMGKKALAAVLGD-----------RTDGTA--------------------------ERL
RQALTASQWACRQV----GNLYTGSLYLALMSYLQN------------------------
-----------GDAHRGSRLGLFSYG--SGAEGEFFTGILQPQFAENIL---PLTPALRQ
RQRVSVTEYERL----F----DEQ---LGMNPADVAFTTENDA-----------------
CPFVLTGQQDHQRQYRAN-------------
>NZ_AAPZ02000002.1|c1|719932-721089|+|ZP_03074439.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MRIGIDKMAFATTNDYLDLVELAKE
-RGVDPNKFTIGIGQDLQAVVPPTQDIVTLGATAAKKLL--------TPELEKNISTVIV
ATESGIDNSKASAIYIKHLLGLSDFIRTVEMKEACYSATAAIQFAKGVVALN--PQETVL
VIAADIARYGLNTPG-----------EVTQGAGAVAMLISRNPHILTLE-DTTVAYSKDI
MDFWRPLYATEAL----VDGKYSTNVYIEFFLQTFTRYQQLTGRE--LADFAALTFHMPF
TKMGKKGLEGLLKD-----------RNDEVA--------------------------QRL
RTQLTASQLFSRQV----GNLYTGSLYLSLMSLLQN------------------------
-----------SDLRAESRIGLFSYG--SGAEGEFYTGILEDGYEHYMN---NIQEELKH
RHQVSVAEYEKL----F----SSQ---LGMNDRDIEFDVTTDP-----------------
LPFVLKGQKDHQRIYEAK-------------
>NC_008497.1|c1|1336395-1337564|-|YP_795493.1|3-hydroxy-3-methylglutaryl_CoA_synthase
---------------------------------MTVKVGIDKIGFYTPNLYLDMVDLAHA
-RGADPAKYQVGIGQSKQAVIPPTQDVVTMAANAAAQIL--------TPTIKTQIAMVLF
GTESGIDNSKATAVYLAHLLELSPQTRAVELKQACYGATAGLQLAADYVRVH--PQAKVL
VIGADIARYGLRTAG-----------EVTQGGGAVAMLVAANPQILELE-ATSSYHTADV
MDFWRPTYRTEAL----VDGKYSTNVYLDFFAAVWADYQRQTKLT--IADFAAFTFHLPF
TKMGRKGLRQILPT-----------ATPEHQ--------------------------AQL
TAAFEASQADNRDV----GNLYTGSLYLSFLSLLRH------------------------
-----------GHLQAGQRIGFFSYG--SGAEGEFFSGLIQPNYRQGFDDA-GLTDLLAN
RRAVSVAEYEQL----Y----NQQ---LSSDGQDMQLAVGQEQ-----------------
APYYLAGRQHEQRVYRRQ-------------
>NC_012984.1|c1|1833303-1834472|-|YP_003063311.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKVGIDKLHFATSHLYVDMAELATA
-RQAEPDKYLIGIGQSKMAVIPPSQDAVTLAANAAAPML--------TATDIAAIDLLVV
GTESGIDNSKASAIYVAKLLGLSQRVRTIEMKEACYAATAGVQLAQDHVRVH--PDKKAL
VIGSDVARYGLNTPG-----------EPTQGGGAVAMLISADPKVLALG-TESSLLSEDV
MDFWRPLYHTEAL----VDGKYSSNIYIDYFQDVFKNYLQTTQTS--PDALTALVFHLPY
TKMGLKALRSVLPL-----------VDAEKQ--------------------------AQW
LAHFEHARQLNRQV----GNLYTGSLYLSLLSQLLT-D----------------------
-----------PQLQPGNRLGLFSYG--SGAEGEFYTGVIQPDYQAGLDHG--LPQRLAR
RRRVSVAEYEAL----F----SHQ---LQWRADDQSVSYADDP-----------------
HRFVLTGQKDEQRQYLDQQV-----------
>NZ_ACKZ01000020.1|c1|108704-109864|-|ZP_05737892.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNIGIDKIGFFVPPTALDMETLAVA
-RGVEPAKYTIGIGQSTMAVAPVTQDIVTLAANAALSII--------DDADRESIDMILF
GTETGIDQSKSAAVYMQRMLGLSNRVRSVELKHACYGATAALQLAKGHIALN--PSSKVL
VIASDIAKYGLNSGG-----------EPTQGAGAVAMVVSESPRLLVLD-NETSLFTDDV
MDFWRPNYEAYPL----VDGQFSNEQYIRFFSEVWKNYQEKTHCE--FSDFEAICFHLPY
TKMGMKAFKPFLEE-----------MSEEER--------------------------ERF
TARYQEASIYNRHV----GNIYTGSLFLSFISLLEN-S----------------------
-----------SVLVAGDRIGFFSYG--SGAVGEFFAGELVEGFENQLHIA-EHKALLEN
RKMLTVEEYEEI----F-----ME---VVDSSGEQTFTREDN------------------
SPVTLTGVKNHERQYTIK-------------
>NC_007576.1|c1|1459083-1460246|-|YP_396093.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MQIGIDKLGLFTPNTYLDLVMLANA
-RGVDPDKFTIGIGQDQMAIAPLSQDSVTMGANAALDLL--------EGESRDNISLLIL
GTESGIDQSKAGAIYIQRLLGLSN-ARTFEIKEACYGATAGLMTAYDYVAAH--PDQKAL
VIGSDIARYGLETPG-----------EVTQGAGAVAMLVSAQPRLMVLE-PETSIHSADI
QDFWRPNYSKEAF----ARGKYSTEQYIEFFQKTWADYRAKTGRT--IADFKALAFHLPY
TKMGLKALRTILDE-----------GSETQQ--------------------------AQL
LERYAESTLYSRQI----GNIYTGALYLGFLSLLEH-S----------------------
-----------TNLEAGDRIGLFSYG--SGAVSEFFTGILQPGFEKQLAKQ-KHADLLAN
RRQLTMVEYETQ----F----QTE---LPEDGSEYEIDLTMDN-----------------
APIILKGVKDHERIYMTR-------------
>NC_004193.1|c5|2287884-2289050|-|NP_693169.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKIGFYAPHLYLDMNELAEE
-RGVEPEKFTIGIGQEKMAVPPITQDTVTLAANAAAQIL--------DETDKQDIDMVIF
GTESGIDHSKSAAVNVHQLLGLQPHARAIELKQACYGATAGIQMARGHIALN--PNRKVL
VLGSDIARYGLRTPG-----------ESTQGAGAVALLISADPSIMAIE-QESTYYTDDI
MDFWRPVYSDIAF----VDGKYSNEQYIAFFQKVWNAYKEQTNRG--LEDFAAICFHLPY
TKMGLKALRTVLDE-----------VEENTQ--------------------------THL
KEQYRLSTQYNRNI----GNIYTGSLYLSLLSLLEN-S----------------------
-----------NELTAGDKIGMYSYG--SGAVGEFFSGVLQEGFEKQLHQT-KHNAMFEK
RQKISVSEYEKI----F----EQQ---IPTDGSVTEWSTKEDP-----------------
AEICLTGIQNHQRIYQVK-------------
>NC_013891.1|c1|1361386-1362552|+|YP_003464571.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKIGFYTPAFYVDMVELAEA
-RNIDPNKFTIGIGQDKMAFAPVTQDSVTMGANAAKQIL--------DEEDLKAIDLVIL
ATESGIDESKAGAVYIHRLLGIQPFSRSIEIKEACYGATAGINLAKDYVAKH--SESKVL
VIGSDIARYGLATAG-----------EATQGAGAVAMVISANPRCITLE-DDNVFYTEDI
MDFWRPVYSEYAC----VEGKYSTEQYIHFFDTIWTKYTEKFNRN--LEDFAAICFHLPY
TKMGKKALDLIIKT-----------APSEVQ--------------------------EKL
LENYRLSTLYSRNI----GNIYTGSLYLSFISLLDH-Q----------------------
-----------DSLQENDKIGFFSYG--SGAVAEFFHGVLQADYKKYIRKN-EHAELLNN
RTKLSVADYETK----F----KQQ---LPKDGSTLEIDPASDP-----------------
AEIMLTGIQDHKRQYLKK-------------
>NZ_AARZ02000001.1|c1|133826-134992|-|ZP_05234481.1|hypothetical_protein
-----------------------------------MKIGIDKIGFYTPAFYVDMTELAEA
-RNIDPNKFTIGIGQDKMAFAPITQDSVTMGANAALQIL--------DEEDLKKIDLVIL
ATESGIDESKAGAVYIHRLLGIQPFSRAIEIKEACYGATAGINLAKDYVAKH--PDSKVL
VIGSDIARYGLATGG-----------EATQGAGAVAMVIAADPRCITLE-DDNVFYTEDI
MDFWRPVYSEYAC----VEGKYSTEQYIHFFQTIWEKYSAKFGKN--LEDFAAICFHLPY
TKMGKKALDTIIET-----------APSDVQ--------------------------EKL
LENYRLSTLYSRNV----GNIYTGSLYLSFISLLDN-Q----------------------
-----------PDLQAEDKIGFFSYG--SGAVGEFFHGVLQPDYKKYIRKD-EHAELLAN
RTKLAIPDYETK----F----KQQ---LPKDGSIFEVDPASDP-----------------
AAIVLTGIQEHKRQYIKK-------------
>NC_013766.1|c1|1514186-1515352|+|YP_003413666.1|hypothetical_protein
-----------------------------------MKIGIDKIGFYTPAFYVDMVELAEA
-RNIDPNKFTIGIGQDKMAFAPITQDSVTMGANAALQIL--------DEEDLKKIDLVIL
ATESGIDESKAGAVYIHRLLGIQPFSRAIEIKEACYGATAGINLAKDYVAKH--PDSKVL
VIGSDIARYGLATGG-----------EATQGAGAVAMVIAGDPRCITLE-DDNVFYTEDI
MDFWRPVYSEYAC----VEGKYSTEQYIHFFQTIWEKYSAKFGKN--LEDFAAICFHLPY
TKMGKKALDTIIET-----------APSDVQ--------------------------EKL
LENYRLSTLYSRNV----GNIYTGSLYLSFISLLDN-Q----------------------
-----------PDLQAEDKIGFFSYG--SGAVGEFFHGVLQPDYKKYIRKD-EHAELLAN
RTKLAIPDYETK----F----KQQ---LPKDGSIFEVDPASDP-----------------
AAIVLTGIQEHKRQYIKK-------------
>NZ_AARP03000025.1|c1|5190-6356|+|ZP_05246300.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKIGFYTPAFYVDMTELAEA
-RNIDPNKFTIGIGQDKMAFAPITQDSVTMGANAALQIL--------DEEDLKKIDLVIL
ATESGIDESKAGAVYIHRLLGIQPFSRAIEIKEACYGATAGINLAKDYVAKH--PDRKVL
VIGSDIARYGLATGG-----------EATQGAGAVAMVIAANPRCITLE-DDNVFYTEDI
MDFWRPVYSEYAC----VEGKYSTEQYIHFFQTIWEKYSAKFGKN--LEDFAAICFHLPY
TKMGKKALDTIIET-----------APSEVQ--------------------------ERL
LENYRLSTLYSRNV----GNIYTGSLYLSFISLLDN-Q----------------------
-----------ADLQAEDKIGFFSYG--SGAVGEFFHGILQPDYKKYIRKD-EHAELLAN
RTKLTISDYETK----F----KQQ---LPKDGSTFEIDPASDP-----------------
AAIVLTGIQDHKRQYIKK-------------
>NC_011660.1|c1|1192378-1193544|-|YP_002350115.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKIGFYTPAFYVDMTELAEA
-RNIDPNKFTIGIGQDKMAFAPITQDSVTMGANAALQIL--------DEEDLKKIDLVIL
ATESGIDESKAGAVYIHRLLGIQPFSRAIEIKEACYGATAGINLAKDYVAKH--PDSKVL
VIGSDIARYGLATGG-----------EATQGAGAVAMVIAANPRCITLE-DDNVFYTEDI
MDFWRPVYSEYAC----VEGKYSTEQYIHFFQTIWEKYSAKFGKN--LEDFAAICFHLPY
TKMGKKALDTIIET-----------APSEVQ--------------------------ERL
LENYRLSTLYSRNV----GNIYTGSLYLSFISLLDN-Q----------------------
-----------ADLQAEDKIGFFSYG--SGAVGEFFHGILQPDYKKYIRKD-EHAELLAN
RTKLTISDYETK----F----KQQ---LPKDGSTFEVDPASDP-----------------
AAIVLTGIQDHKRQYIKK-------------
>NZ_ACGF01000109.1|c1|54957-56264|-|ZP_03937087.1|hydroxymethylglutaryl-CoA_synthase
---------------------------MSNTSKNTPKVGIDRITFATPNCYLSMRDLAIE
-RGIDPNKFTIGIGQSQQAVPPNHQDIVTLGAQAALPLM--------QYIDSNRLKMVIV
GTESGVDASKSSALYIHKLLNLSSWVRCVEVKEACYGGTAALMMARDYVLTH--PGAQVL
VIAADIARYGVGTPG-----------EVTQGAGAVAMLVSENPHVLQIN-DDSVVKSAEI
QDFWRPVYQSTAL----ARGKFSTEQYIRMFCDVWQRYSAENACN--FNDFEAICFHLPY
TKMGLKALRAGLEE------KSSAPITSDTR--------------------------ERL
LARYQDSTQYSRRI----GNIYTGSLYLGLISLLDY-DYFKNFDDSAVDGDSEVSCDLSS
ATHTNESPTCLSPLLSGQKIGLFSYG--SGAVAEFFSATLVPDWRSALFSN-QHLKSLNN
RTQLSVSRYEEM----F----NSA---APYSPQDFISSQKNRSG----------------
ARFVLDSIASQERNYRSI-------------
>NZ_GG770225.1|c1|613914-615302|+|ZP_06755756.1|hydroxymethylglutaryl-CoA_synthase
--------MLQNKSSEENFPPSSVPLPAQQSFADFPPVGIDSLALYTPGFYLDLTELAQA
-RGVDPNKYTIGIGQDQQAVAPSNQDIVTMGAAAGLKALYFADSAGASDTGHTNIGLLVV
GTESGVDASKASALFIHDLIGLSPWCRSIEIKEACYGGTAGLMTAVDYVHTH--PGKKAL
VIASDIARYGLNTPG-----------EVTQGAGAVAMVISENPRILALE-PQSTAYSRSI
GDFWRPVYTDMAL----ARGKYSTEEYINFFHRVWKQYKNETGRS--VKDFAAICFHLPY
TKMGMKAFRGVLDSDISDNNISDSDISDSKSADNNNNKTGASADSDISVHAHGHFLKETL
EKRYQASTLYSRQI----GNIYTGSLYLSLLSLLDH-D----------------------
-----------SSLSSGDRLGLFSYG--SGAVGEFFSGILQDGYSHALHRS-HTQTLLHR
RHKVSVAEYEKI----F----NDA---IPYQAGDVQTDQVHRDP---------------W
NPFILDRVEGQERIYRRL-------------
>NZ_ACIZ01000074.1|c1|7413-8585|-|ZP_04441360.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDAIEMDTPDFYVDLVKLAKV
-RGDDPNKYTIGIGQDEQAVPPSSQDIVTLGANAAAKVL--------TPASRASLGMILV
GTESGVDASKSAALFIHDLLALPEWVRAVELKEACYGGTAALMMARDYVASH--PDKSVL
VIAADIARYGLATAG-----------EVTQGAGAVAMIVKADPCLLTIE-PDSVYRSASI
NDFWRPVYQDTAL----AQGKYSTEQYLAFFKTVWERYQADHHLS--AHDFAAMTFHLPY
TKMGKKALDLVLPT-----------TDDASA--------------------------QRL
KNRFEASTRYCRRI----GNIYTGSLYLGLLSLLDH-D----------------------
-----------TTLQAGDRIGLFSYG--SGAVAEFFSGILQPQFKEQLHAA-EHAQQLTK
RQELPVPEYEAV----F----SDK---VPYDADDYRPDPAYYR-----------------
GQFILTGVIGQERHYEKHQS-----------
>NZ_ABWJ01000010.1|c1|27517-28689|+|ZP_03211418.1|3-hydroxy-3-methylglutaryl_CoA_synthase
-----------------------------------MKIGIDAIEMDTPDFYVDLVKLAKV
-RGDDPNKYTIGIGQDEQAVPPSSQDIVTLGANAAAKVL--------TPASRASLGMILV
GTESGVDASKSAALFIHDLLVLPEWVRAVELKEACYGGTAALMMARDYVASH--PDKSVL
VIAADIARYGLATAG-----------EVTQGAGAVAMIVKADPRLLTIE-PDSVYRSASI
NDFWRPVYQDTAL----AQGKYSTEQYLAFFKTVWERYQADHHLS--AHDFAAMTFHLPY
TKMGKKALDLVLPT-----------TDDASA--------------------------QRL
KNRFEASTRYCRRI----GNIYTGSLYLGLLSLLDH-D----------------------
-----------TTLQAGDRIGLFSYG--SGAVAEFFSGILQPQFKEQLHAA-EHAQQLTK
RQELPVPEYEAA----F----SDK---VPYDADDYRPDPAYYR-----------------
GQFILTGVIGQERHYEKHQS-----------
>NC_009009.1|c1|332250-333428|-|YP_001034345.1|hydroxymethylglutaryl-CoA_synthase,_putative
-----------------------------------MTIGIDKIGFATSNYVLKLNDLAAA
-RGTDPDKLSKGLLLKELSIAPLTEDIVTLGAAAADPIL--------TAEDKEKIDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALDYAKLHIEKH--PDSKVL
VLASDIAKYGINTPG-----------EPTQGAGAISMLISSNPRILAFN-DDNVAQTRDV
MDFWRPNYSTTPY----VNGLYSTQQYLDSLKTTWAEYQKRHKLA--LKDFAAYCFHLPY
PKLALKGLNKIMDK----------SLPQEQQ--------------------------DQL
RKNFEASILYSQKV----GNIYTGSLFLGLLSLLEN-S----------------------
-----------DNLKAGDRIALFGYG--SGAVSEIFSANLVEGYEKHLSQT--RLEELDQ
RQALSIPNYERI----F--FEEAE---LDAEGNASFSGYEE-------------------
QSFALAEIAEHQRKYIKVEKSS---------
>NZ_GG730097.1|c1|988176-989372|-|ZP_06199478.1|hydroxymethylglutaryl-CoA_synthase
---------------------------MNEKTEVNMTIGIDKIGFATSQYVLKLQDLAEA
-RGVDPEKFSKGLLLNEISIAPLTEDIVTLAASASNSIL--------TDKEKEEIDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALHYAKLHVENS--PESKVL
VIASDIAKYGVATPG-----------EPTQGAGSVAMLITQNPRIMAFN-NDNVAQTRDI
MDFWRPNYSSTPY----VNGVYSTQQYLDSLTTTWDEYKKRYDWT--MGDFAAICFHLPY
PKLALKGLRKMMDK----------TLSQEKQ--------------------------DSL
QENFDKSILYSQMI----GNIYTGSLFLGLLSLLEN-A----------------------
-----------ENLKAGDKIALYSYG--SGAVSEFFSGELVEGYEAYLDKE--RLSKLKQ
RTALSVADYEKV----F--FEELQ---LDESGSAQFAGYEH-------------------
QDYALVEIVDHQRRYSKVEK-----------
>NC_011900.1|c2|1670757-1671929|-|YP_002511614.1|3-hydroxy-3-methylglutaryl_coenzyme_A_synthase
-----------------------------------MTIGIDKIGFATSQYVLKLQDLAEA
-RGIDPEKLSKGLLLKELSIAPLTEDIVTLAASASDSIL--------TEQERQEVDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALHYAKLHVENS--PESKVL
VIASDIAKYGIETPG-----------EPTQGAGSVAMLITQNPRMMAFN-NDNVAQTRDI
MDFWRPNYSTTPY----VNGVYSTQQYLDSLKTTWLEYQKRYQLT--LDDFAAVCFHLPY
PKLALKGLKKIMDK----------NLPQEKK--------------------------DLL
QKHFDQSILYSQKV----GNIYTGSLFLGLLSLLEN-T----------------------
-----------DSLKAGDKIALYSYG--SGAVAEFFSGELVEGYEAYLDKD--RLNKLNQ
RTALSVADYEKV----F--FEEVN---LDETNSAQFAGYEN-------------------
QDFALVEILDHQRRYSKVEK-----------
>NC_003098.1|c2|1552473-1553669|-|NP_359163.1|hydroxymethylglutaryl-CoA_synthase
---------------------------MNDKTEVNMTIGIDKIGFATSQYVLKLQDLAEA
-RGIDPEKLSKGLLLKELSIAPLTEDIVTLAASASDSIL--------TEQERQEVDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALHYAKLHVENS--PESKVL
VIASDIAKYGIETPG-----------EPTQGAGSVAMLITQNPRMMAFN-NDNVAQTRDI
MDFWRPNYSTTPY----VNGVYSTQQYLDSLKTTWLEYQKRYQLT--LDDFAAVCFHLPY
PKLALKGLKKIMDK----------SLPQEKK--------------------------DLL
QKHFDQSILYSQKV----GNIYTGSLFLGLLSLLEN-T----------------------
-----------DSLKAGDKIVLYSYG--SGAVAEFFSGELVEGYEAYLDKD--RLNKLNQ
RTALSVADYEKV----F--FEEVN---LDETNSAQFAGYEN-------------------
QDFALVEILDHQRRYSKVEK-----------
>NZ_ABAC01000004.1|c1|116484-117680|-|ZP_01825346.1|hydroxymethylglutaryl-CoA_synthase
---------------------------MNDKTEVNMTIGIDKIGFATSQYVLKLQDLAEA
-RGIDPEKLSKGLLLKELSIAPLTEDIVTLAASASDSIL--------TEQERQEVDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALHYAKLHVENS--PESKVL
VIASDIAKYGIETPG-----------EPTQGAGSVAMLITQNPRMMAFN-NDNVAQTRDI
MDFWRPNYSTTPY----VNGVYSTQQYLDSLKTTWLEYQKRYQLT--LDDFAAVCFHLPY
PKLALKGLKKIMDK----------SLPQEKK--------------------------DLL
QKHFDQSILYSQKV----GNIYTGSLFLGLLSLLEN-T----------------------
-----------DSLKAGDKIALYSYG--SGAVAEFFSGELVEGYEAYLNKD--RLNKLNQ
RTALSVADYEKV----F--FEEVN---LDETNSAQFAGYEN-------------------
QDFALVEILDHQRRYSKVEK-----------
>NZ_AAZZ01000002.1|c1|112471-113667|-|ZP_01817466.1|hydroxymethylglutaryl-CoA_synthase
---------------------------MNDKTEVNMTIGIDKIGFATSQYVLKLQDLAEA
-RGIDPEKLSKGLLLKELSIAPLTEDIVTLAASASDSIL--------TEQERQEVDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALHYAKLHVENS--PESKVL
VIASDIAKYGIETPG-----------EPTQGAGSVAMLITQNPRMMAFN-NDNVAQTRDI
MDFWRPNYSTTPY----VNGVYSTQQYLDSLKTTWLEYQKRYQLT--LDDFAAVCFHLPY
PKLALKGLKKIMDK----------NLPQEKK--------------------------DLL
QKHFDQSILYSQKV----GNIYTGSLFLGLLSLLEN-T----------------------
-----------DSLKAGDKIALYSYG--SGAVAEFFSGELVEGYEAYLDKD--RLNKLNQ
RTALSVADYEKV----F--FEEVN---LDETNSAQFAGYEN-------------------
QDFALVEILDHQRRYSKVEK-----------
>NC_003028.3|c2|1631071-1632267|-|NP_346164.1|hydroxymethylglutaryl-CoA_synthase
---------------------------MNDKTEVNMTIGIDKIGFATSQYVLKLQDLAEA
-RGIDPEKLSKGLLLKELSIAPLTEDIVTLAASASDSIL--------TEQERQEVDMVIV
ATESGIDQSKAAAVFVHGLLGIQPFARSFEIKEACYGATAALHYAKLHVENS--PESKVL
VIASDIAKYGIETPG-----------EPTQGAGSVAMLITQNPRMMAFN-NDNVAQTRDI
MDFWRPNYSTTPY----VNGVYSTQQYLDSLKTTWLEYQKRYQLT--LDDFAAVCFHLPY
PKLALKGLKKIMDK----------SLPQEKK--------------------------DLL
QKHFDQSILYSQKV----GNIYTGSLFLGLLSLLEN-T----------------------
-----------DSLKAGDKIALYSYG--SGAVAEFFSGELVEGYEAYLDKD--RLNKLNQ
RTALSVADYEKV----F--FEEVN---LDETNSAQFAGYEN-------------------
QDFALVEILDHQRRYSKVEK-----------
>NC_006086.1|c1|707225-708439|-|YP_060022.1|hydroxymethylglutaryl-CoA_synthase
----------------------MGKTIKITKRRTNMTIGIDKIGFATSQYVLKLEDLALA
-RQVDPAKFSQGLLIESFSVAPITEDIITLAASAADQIL--------TDEDRSKIDMVIL
ATESSTDQSKASAIYVHHLVGIQPFARSFEVKQACYSATAALDYAKLHVASK--PDSRVL
VIASDIARYGVGSPG-----------ESTQGSGSIALLVTTNPRILALN-EDNVAQTRDI
MDFWRPNYSFTPY----VDGIYSTKQYLNCLETTWQAYQKRENLQ--LSDFAAVCFHIPF
PKLALKGLNNIMDN----------TVPPEHR--------------------------EKL
IEAFQASITYSKQI----GNIYTGSLYLGLLSLLEN-S----------------------
-----------KVLQSGDKIGFFSYG--SGAVSEFYSGQLVAGYDKMLMTN--RQTLLDQ
RTRLSVSKYEDL----F--YEQVQ----LDDNGNANFDIYLT------------------
GKFALTAIKEHQRIYRTNDKN----------
>NC_008024.1|c1|752828-754042|-|YP_602273.1|Hydroxymethylglutaryl-CoA_synthase
----------------------MGKTIKITKRRTNMTIGIDKIGFATSQYVLKLEDLALA
-RQVDPAKFSQGLLIESFSVAPITEDIITLAASAADQIL--------TDEDRAKIDMVIL
ATESSTDQSKASAIYVHHLVGIQPFARSFEVKQACYSATAALDYAKLHVASK--PDSRVL
VIASDIARYGVGSPG-----------ESTQGSGSIALLVTANPRILALN-KDNVAQTRDI
MDFWRPNYSFTPY----VDGIYSTKQYLNCLETTWQAYQKRENLQ--LSDFAAVCFHIPF
PKLALKGLNNIMDN----------TVPPEHR--------------------------EKL
IEAFQASITYSKQI----GNIYTGSLYLGLLSLLEN-S----------------------
-----------KVLQSGDKIGFFSYG--SGAVSEFYSGQLVAGYDKMLMTN--RQALLDQ
RTRLSVSKYEDL----F--YEQVQ----LDDNGNANFDIYLT------------------
GKFALTAIKEHQRIYHTNDKN----------
>NC_004070.1|c1|660150-661325|-|NP_664404.1|putative_3-hydroxy-3-methylglutaryl-coenzyme_A
-----------------------------------MTIGIDKIGFATSQYVLKLEDLALA
-RQVDPAKFSQGLLIESFSVAPITEDIITLAASAADQIL--------TDEDRAKIDMVIL
ATESSTDQSKASAIYVHHLVGIQPFARSFEVKQACYSATAALDYAKLHVASK--PDSRVL
VIASDIARYGVGSPG-----------ESTQGSGSIALLVTADPRILALN-EDNVAQTRDI
MDFWRPNYSFTPY----VDGIYSTKQYLNCLETTWQAYQKRENLQ--LSDFAAVCFHIPF
PKLALKGLNNIMDN----------TVPPEHR--------------------------EKL
IEAFQASITYSKQI----GNIYTGSLYLGLLSLLEN-S----------------------
-----------KVLQSGDKIGFFSYG--SGAVSEFYSGQLVAGYDKMLMTN--RQALLDQ
RTRLSVSKYEDL----F--YEQVQ----LDDNGNANFDIYLT------------------
GKFALTAIKEHQRIYHTNDKN----------
>NC_002737.1|c1|728857-730032|-|NP_269080.1|putative_3-hydroxy-3-methylglutaryl-coenzyme_A
-----------------------------------MTIGIDKIGFATSQYVLKLEDLALA
-RQVDPAKFSQGLLIESFSVAPITEDIITLAASAADQIL--------TDEDRAKIDMVIL
ATESSTDQSKASAIYVHHLVGIQPFARSFEVKQACYSATAALDYAKLHVASK--PDSRVL
VIASDIARYGVGSPG-----------ESTQGSGSIALLVTANPRILALN-EDNVAQTRDI
MDFWRPNYSFTPY----VDGIYSTKQYLNCLETTWQAYQKRENLQ--LSDLAAVCFHIPF
PKLALKGLNNIMDN----------TVPPEHR--------------------------EKL
IEAFQASISYSKQI----GNIYTGSLYLGLLSLLEN-S----------------------
-----------KVLQSGDKIGFFSYG--SGAVSEFYSGQLVAGYDKMLMTN--RQALLDQ
RTRLSVSKYEDL----F--YEQVQ----LDDNGNANFDIYLT------------------
GKFALTAIKEHRRIYHTNDKN----------
>NZ_AAFV01000003.1|c1|6881-8056|+|ZP_00366611.1|COG3425:_3-hydroxy-3-methylglutaryl_CoA
-----------------------------------MTIGIDKIGFATSQYVLKLEDLALA
-RQVDPAKFSQGLLIESFSVAPITEDIITLAASAADQIL--------TDEDRAKIDMVIL
ATESSTDQSKASAIYVHHLVGIQPFARSFEVKQACYSATAALDYAKLHVASK--PDSRVL
VIASDIARYGVGSPG-----------ESTQGSGSIALLVTANPRILALN-EDNVAQTRDI
MDFWRPNYSFTPY----VDGIYSTKQYLNCLETTWQAYQKRENLQ--LSDFAAVCFHIPF
PKLALKGLNNIMDN----------TVPPEHR--------------------------EKL
IEAFQASITYSKQI----GNIYTGSLYLGLLSLLEN-S----------------------
-----------KVLQSGDKIGFFSYG--SGAVSEFYSGQLVAGYDKMLMTN--RQTLLDQ
RTRLSVSKYEDL----F--YEQVQ----LDDNGNANFDIYLT------------------
GKFALTAIKEHRRIYHTNDKN----------
>NZ_ACLO01000092.1|c1|160929-162095|+|ZP_04063032.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MSIGIDKIGFATSQYVLNMADLALA
-RGAEPEKFSKGLMLDATSITPITEDIVTLASDAAADIL--------NDDDKNAIDMVIV
ATESSIDQSKAAAVYVHSLLGIQPFARSFEMKEACYAATAGLNYAKLHVAAH--PDSKVL
VIASDIARYGVGSSG-----------ESTQGAGAVAMLVSQNPRILELA-DDNVVQTRDV
MDFWRPNYSSTPY----VQGIYSTKQYLDSLKTTWAAYQERHQTN--FADFAAFCLHLPY
PKLALKGLNKIIPK----------DLNPENK--------------------------ERL
TNNFDASITYSRQI----GNIYTGSLYLGLLSLLEQ-S----------------------
-----------QDIKAGDKIGFFSYG--SGAVSEIFSGRLVEGYKDLLRSD--RLDTFAK
RQHLSVADYEKL----F--YEEAQ---LDDTGSTQFADYQT-------------------
GAFRLAEISEHQRIYKGN-------------
>NC_012004.1|c1|749251-750426|-|YP_002562108.1|3-hydroxy-3-methylglutaryl_coenzyme_A_synthase
-----------------------------------MNIGIDKIGFATGQYVLNMEDLAQA
-RQTDPEKFSQGLMLDAISISPITEDIVTLAASAAASIL--------DEEDKKKIDMVIL
ATESSIDQSKAASVYVHHLLGIQPFARSIEMKEACYAATAALDYAKLHVTMH--PESRVL
VIASDIAKYGIKSAG-----------EPTQGSGSVALLIKTNPRIAILN-KDNVAQTRDV
MDFWRPNYSTTPY----VNGIYSTKQYLDSLKTTWKYYQDQNQVT--LSDFAAFCFHIPF
PKLAFKGLTKLMDK----------SLTPQHK--------------------------NAL
QEAFQASIQYSRKV----GNIYTGSLYMSLLSLLEN-S----------------------
-----------SAVKAGDRIGMFSYG--SGAVSEIFSLQLVEGYEKQLNTE--RIHYLNS
RQKLTVSEYEDL----F--YEECE----LDDSGNAKFKQYQT------------------
NDFSLTEIQEHQRIYKKNDNA----------
>NZ_AAJR01000044.1|c1|10783-12060|-|ZP_00785889.1|hydroxymethylglutaryl-CoA_synthase
MRNKTLKVKAFFHIFSFFMVKWNLAKMTFIQKGLPMKIGIDKIGFATSQYVLEMTDLAIA
-RQVDPEKFSKGLLLDSLSITPVTEDIVTLAASAANDIL--------SDEDKETIDMVIV
ATESSIDQSKAASVYVHQLLEIQPFARSFEMKEACYSATAALDYAKLHVEKH--PDSKVL
VIASDIAKYGIKSTG-----------ESTQGAGSIAMLISQNPSILELK-EDHLAQTRDI
MDFWRPNYSDVPY----VNGMFSTKQYLDMLKTTWKVYQKRFNTS--LSDYAAFCFHIPF
PKLALKGFNKILDN----------NLDEQKK--------------------------AEL
QENFEHSITYSKKI----GNCYTGSLYLGLLSLLEN-S----------------------
-----------QNLKAGDQIAFFSYG--SGAVAEIFTGQLVDGYQNKLQSD--RMDQLNK
RQKITVTEYEKL----F---FEKT---ILDENGNANFNTYRT------------------
GTFSLDSICEHQRIYXKIXX-----------
>NZ_AAJS01000117.1|c1|548-1825|+|ZP_00784157.1|hydroxymethylglutaryl-CoA_synthase
MRNKTLKVKAFFHIFSFFMVKWNLAKMTFIQKGLPMKIGIDKIGFATSQYVLEMTDLAIA
-RQVDPEKFSKGLLLDSLSITPVTEDIVTLAASAANDIL--------SDEDKETIDMVIV
ATESSIDQSKAASVYVHQLLEIQPFARSFEMKEACYSATAALDYAKLHVEKH--PDSKVL
VIASDIAKYGIKSTG-----------ESTQGAGSIAMLISQNPSILELK-EDRLAQTRDI
MDFWRPNYSDVPY----VNGMFSTKQYLDMLKTTWKEYQKRFNTS--LSDYAAFCFHIPF
PKLALKGFNKILDN----------NLDEQKK--------------------------AEL
QENFEHSITYSKKI----GNCYTGSLYLGLLSLLEN-S----------------------
-----------QNLKAGDQIAFFSYG--SGAVAEIFTGQLVDGYQNKLQSD--RMDQLNK
RQKITVTEYEKL----F---FEKT---ILDENGNANFNTYRT------------------
GTFSLDSICEHQRIYKKINN-----------
>NZ_AAJO01000043.1|c1|8362-9639|-|ZP_00780828.1|hydroxymethylglutaryl-CoA_synthase
MRNKTLKVKAFFHIFSFFMVKWNLAKMTFIQKGLPMKIGIDKIGFATSQYVLEMTDLAIA
-RQVDPEKFSKGLLLDSLSITPVTEDIVTLAASAANDIL--------SDEDKETIDMVIV
ATESSIDQSKAASVYVHQLLEIQPFARSFEMKEACYSATAALDYAKLHVEKH--PDSKVL
VIASDIAKYGIKSTG-----------ESTQGAGSIAMLISQNPSILELK-EDHLAQTRDI
MDFWRPNYSDVPY----VNGMFSTKQYLDMLKTTWKEYQKRFNTS--LSDYAAFCFHIPF
PKLALKGFNKILDN----------NLDEQKK--------------------------AEL
QENFEHSITYSKKI----GNCYTGSLYLGLLSLLEN-S----------------------
-----------QNLKAGDQIAFFSYG--SGAVAEIFTGQLVDGYQNKLQSD--RMDQLNK
RQKITVTEYEKL----F---FEKT---ILDENGNANFNTYRT------------------
GTFSLDSICEHQRIYKKINN-----------
>NZ_AAFA03000010.1|c1|7442-8596|+|ZP_03624914.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNIGIDKIGFAAPDYVLDLADLAQA
-RNVDPNKFKIGLLQSEMAVAPVTQDIISLGAKAAEAIL--------TEEDKQTIDMVIV
GTESSVDQSKAAAVTIHGLLGIQPFARSIEMKEACYGATAGLSLAKSHIAQF--PESKVL
VIASDIAKYGVASGG-----------EPTQGAGAVAMLVTANPQILVLN-NDNVCQTRDI
YDFWRPNYDKYPR----VDGKFSTEQYTDCLTTTFDYYQQKTGKT--LNDFAAMCLHIPF
SKQGLKGLQAIAQD-------------EETL--------------------------SRL
TERFQEAIVYNKVV----GNIYTGSIFLSLLSLLEN-S----------------------
-----------RALETGDQILFYSYG--SGAVCEIFSGQLVEDYRDHLQEN--RLEQLNQ
RTKLSVKEYEQV----F--FEEIT---LDETGSSLNLPEDQ-------------------
SPFALIKVDNHKRIYRK--------------
>NC_009442.1|c1|1555482-1556681|+|YP_001199007.1|3-hydroxy-3-methylglutaryl_CoA_synthase
--------------------MRKQVNLSFVHKGYIMNIGIDKIGFAAPDYVLDLADLAQA
-RNVDPNKFKIGLLQSEMAVAPVTQDIISLGAKAAEAIL--------TEEDKQTIDMVIV
GTESSVDQSKAAAVTIHGLLGIQPFARSIEMKEACYGATAGLSLAKSHIAQF--PESKVL
VIASDIAKYGVASGG-----------EPTQGAGAVAMLVTANPRILVLN-NDNVCQTRDI
YDFWRPNYDKYPR----VDGKFSTEQYTDCLTTTFDYYQQKTGKT--LNDFAAMCLHIPF
SKQGLKGLQAIAQD-------------EETL--------------------------SRL
TERFQEAIVYNKVV----GNIYTGSIFLSLLSLLEN-S----------------------
-----------RALETGDQILFYSYG--SGAVCEIFSGQLVEGYRNHLQEN--RLEQLNQ
RTKLSVKEYEQV----F--FEEIT---LDETGSSLDLPEDQ-------------------
SPFALIKVDNHKRIYRK--------------
>NC_012924.1|c2|1555191-1556345|+|YP_003025470.1|3-hydroxy-3-methylglutaryl_coenzyme_A_synthase
-----------------------------------MNIGIDKIGFAAPDYVLDLADLAQA
-RNVDPNKFKIGLLQSEMAVAPVTQDIISLGAKAAEAIL--------TEEDKQTIDMVIV
GTESSVDQSKAAAVTIHGLLGIQPFARSIEMKEACYGATAGLSLAKSHIAQF--PESKVL
VIASDIAKYGVASGG-----------EPTQGAGAVAMLVTANPRILVLN-NDNVCQTRDI
YDFWRPNYDKYPR----VDGKFSTEQYTDCLTTTFDYYQQKTGKT--LNDFAAMCLHIPF
SKQGLKGLQAIAQD-------------EETL--------------------------SRL
TERFQEAIVYNKVV----GNIYTGSIFLSLLSLLEN-S----------------------
-----------RALETGDQILFYSYG--SGAVCEIFSGQLVEGYRNHLQEN--RLEQLNQ
RTKLSVKEYEQV----F--FEEIT---LDETGSSLDLPEDQ-------------------
SPFALIKVDNHKRIYRK--------------
>NZ_ACDZ02000008.1|c1|176297-177466|-|ZP_04776433.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDKIGFAMPNYYLDIRDLATA
-RGIEPDKFTKGLLQLEMSIPPVSQDIVTLGAQAAYDIL--------DKDDLERIDMIIV
GTESGVDQSKASSVFIHGLLDIQPFVRAIEVKEACYGATAALDFAKNHVMNN--PESKVL
VIASDIAKYGVKSSG-----------ESTQGAGSCAMLVSSNPRILEFN-NDNVCLTRDV
MDFWRPNYSQYAF----VEGRFSTEQYLDCLTTTWNRYIEKTKQS--LNDFSAVCLHLPY
PKLGLKGLTLLLEQ-----------AEEEKK--------------------------EEL
LTRFNESILYSQRV----GNIYTGSLFLGLLSLLEN-N----------------------
-----------NTLEAGNKIGLYSYG--SGAVAEVFSLTLVEGYKNQLRNN--RFDDFGK
RTRISIDEYEKM----F--FRDTA---VDEEGNLDISDIKDE------------------
SRFVLEKIENHKRVYKKQF------------
>NZ_ADAD01000030.1|c1|26336-27505|-|ZP_06010847.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNIGIDKFGLAIPEYFLDIEDLAVA
-RNENANKFSKGLLQLEMSVAPVTQDIVTLGATAAHEFL--------TEEDKKKIDMIII
GTETGVDQSKSASVFIHNLLGIQPFARSVEIKEACYGATAGLDFAKNHILRN--PDSYVL
LIASDIAKYGIGTSG-----------ESTQGAGSCAMLIKKDPNILILN-DDNVCQTRDI
MDFWRPNYSPYPY----VDGHFSTKQYLECLETTWEEYRKRNNKD--LKDFEAFCFHLPF
PKLGLKGLQSIVPK----------GIDKNLK--------------------------EKL
LENLHTSIIYSRRI----GNIYTGSLYLGLLSLLEN-S----------------------
-----------TTLKAGDNIALFSYG--SGAVCEIFSGTLAENFKNHLRNN--RNEDFEK
RKRLSVEQYEKM----F--FEEIS----PDENGNVEFKNDD-------------------
SLFSLKKIEEHKRIYKYNPK-----------
>NC_007350.1|c1|354768-355937|-|YP_300414.1|3-hydroxy-3-methylglutaryl_CoA_synthase
-----------------------------------MTVGIDQINFYVPRFYVDMAKLAES
-RQVDPNKYLLGIGQTEMSVSPMSQDIVSMGANAAKAIV--------TDEDKKQISMVIV
ATESAIDSAKASAVQIHNLLGIQPFARCIEMKEACYAATPAIQLAKDYLAQR--PDEKVL
VIASDTARYGLHSGG-----------EPTQGAGAVAMMISQNPRILELN-DDAVAFTEDV
YDFWRPSGQSYPL----VDGALSKDAYIRSFQESWQEYARRYNKS--LADFKSLCFHVPF
TKMGKKALDSILTD----------DIDAETK--------------------------ERL
TSGYDAATYYNRYV----GNIYTGSLYLSLISLLET------------------------
-----------HDLSANDTIGLFSYG--SGSVGEFFSGKIVEGYQDVLDIQ-GHKDLLNN
REEISVETYESF----FNRFDNLE---FDHETELENEKN---------------------
TIFYLESINDHIRNYNTLN------------
>NC_003923.1|c5|2628292-2629458|+|NP_647284.1|3-hydroxy-3-methylglutaryl_CoA_synthase
-----------------------------------MTIGIDKINFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDII--------TDEDKKKIGMVIV
ATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQLAKDYLATR--PNEKVL
VIATDTARYGLNSGG-----------EPTQGAGAVAMVIAHNPSILALN-EDAVAYTEDV
YDFWRPTGHKYPL----VDGALSKDAYIRSFQQSWNEYAKRQGKS--LADFASLCFHVPF
TKMGKKALESIIDN-----------ADETTQ--------------------------ERL
RSGYEDAVDYNRYV----GNIYTGSLYLSLISLLEN------------------------
-----------RDLQAGETIGLFSYG--SGSVGEFYSATLVEGYKDHLDQA-AHKALLNN
RTEVSVDAYETF----FKRFDDVE---FDEEQDAVHEDR---------------------
HIFYLSNIENNVREYHRPE------------
>NC_002952.2|c4|2710656-2711822|+|YP_041971.1|3-hydroxy-3-methylglutaryl_coenzyme_A_synthase
-----------------------------------MTLGIDKINFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDII--------TDEDKKKIGMVIV
ATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQLAKDYLATR--PNEKVL
VIATDTARYGLNSGG-----------EPTQGAGAVAMVISHNPSILALN-EDAVAYTEDV
YDFWRPTGHKYPL----VDGALSKDAYIRSFQQSWNEYAKRQGKS--LADFASLCFHVPF
TKMGKKALESIIDN-----------ADETTQ--------------------------ERL
RSGYEDAVDYNRYV----GNIYTGSLYLSLISLLEN------------------------
-----------RDLQAGETIGLFSYG--SGSVGEFYSATLVEGYKDHLDQA-AHKALLNN
RTEVSVDAYETF----FKRFDDVD---FDEQQDAVHEDR---------------------
HIFYLSNIENNVREYHRPE------------
>NZ_AASB02000023.1|c1|21080-22246|+|ZP_04864388.1|3-hydroxy-3-methylglutaryl_coenzyme_A_synthase
-----------------------------------MTIGIDKINFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDII--------TDEDKKKIGMVIV
ATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQLAKDYLATR--PNEKVL
VIATDTARYGLNSGG-----------EPTQGAGAVAMVIAHNPSILALN-EDAVAYTEDV
YDFWRPTGHKYPL----VDGALSKDAYIRSFQQSWNEYAKRQGKS--LADFSSLCFHVPF
TKMGKKALESIIDN-----------ADETTQ--------------------------ERL
RSGYEDAVDYNRYV----GNIYTGSLYLSLISLLEN------------------------
-----------RDLQAGETIGLFSYG--SGSVGEFYSATLVEGYKDHLDQA-AHKALLNN
RTEVSVDAYETF----FKRFDDVD---FDEQQDAVHEDR---------------------
HIFYLSNIENNVREYHRPE------------
>NZ_ACJB01000022.1|c1|56569-57747|+|ZP_04817764.1|HMG-CoA_synthase
-------------------------------MIRLMNIGIDRINFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDII--------TDEDKKNIGMVIV
ATESAIDNAKAAAVQIHHLLGIQPFARCFEMKEACYAATPAIQLAKDYLAQR--PNEKVL
VIASDTARYGINSGG-----------EPTQGAGAVAMMISHEPSILKLN-DDAVAYTEDV
YDFWRPTGHKYPL----VAGALSKDAYIKSFQESWNEYARRQGKS--LSDFESLCFHVPF
TKMGKKALDSIIDN-----------ADETTQ--------------------------ERL
KSGYEDAVYYNRYV----GNIYTGSLYLSLISLLET------------------------
-----------RDLKGDQTIGLFSYG--SGSVGEFFSATLVDGFDKHLDIE-GHKSLLNN
RTEVSVEEYESF----FKRFDDLD---FNHEIEQSNEDK---------------------
DIYYLKDIQEDIREYHIPE------------
>NZ_ACHE01000089.1|c1|13274-14509|-|ZP_04826242.1|hydroxymethylglutaryl-CoA_synthase
------------MYKTNFLWYDTSATSKNERMSHLMNIGIDKISFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDII--------TEEDKKNIGMVIV
ATESAIDNAKAAAVQIHHLLGIQPFARCFEMKEACYAATPAIQLAKDYLAQR--PNEKVL
VIASDTARYGIHSGG-----------EPTQGAGAVAMMISHNPSILKLN-DDAVAYTEDV
YDFWRPTGHQYPL----VAGALSKDAYIKSFQESWNEYARRHNKT--LADFASLCFHVPF
TKMGQKALDSIINH-----------ADETTQ--------------------------DRL
NSSYQDAVDYNRYV----GNIYTGSLYLSLISLLET------------------------
-----------RDLKGGQTIGLFSYG--SGSVGEFFSGTLVDGFKEQLDVE-RHKSLLNN
RIEVSVDEYEHF----FKRFDQLE---LNHELEKSNADR---------------------
DIFYLKSIDNNIREYHIAE------------
>NC_002976.3|c2|2146652-2147818|+|YP_189678.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNIGIDKISFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMTVSPVNQDIVSMGANAAKDII--------TEEDKKNIGMVIV
ATESAIDNAKAAAVQIHHLLGIQPFARCFEMKEACYAATPAIQLAKDYLAQR--PNEKVL
VIASDTARYGIHSGG-----------EPTQGAGAVAMMISHNPSILKLN-DDAVAYTEDV
YDFWRPTGHQYPL----VAGALSKDAYIKSFQESWNEYARRHNKT--LADFASLCFHVPF
TKMGQKALDSIINH-----------ADETTQ--------------------------DRL
NSSYQDAVDYNRYV----GNIYTGSLYLSLISLLET------------------------
-----------RDLKGGQTIGLFSYG--SGSVGEFFSGTLVDGFKEQLDVE-RHKFLLNN
RIEVSVDEYEHF----FKRFDQLE---LNHELEKSNADR---------------------
DIFYLKSIDNNIREYHIAE------------
>NC_004461.1|c3|2153608-2154774|+|NP_765665.1|3-hydroxy-3-methylglutaryl_CoA_synthase
-----------------------------------MNIGIDKISFYVPKYYVDMAKLAEA
-RQVDPNKFLIGIGQTEMTVSPVNQDIVSMGANAAKDII--------TEEDKKNIGMVIV
ATESAIDNAKAAAVQIHHLLGIQPFARCFEMKEACYAATPAIQLAKDYLAQR--PNEKVL
VIASDTARYGIHSGG-----------EPTQGAGAVAMMISHNPSILKLN-DDAVAYTEDV
YDFWRPTGHQYPL----VAGALSKDAYIKSFQESWNEYARRHNKT--LADFASLCFHVPF
TKMGQKALDSIINH-----------ADETTQ--------------------------DRL
NSSYQDAVDYNRYV----GNIYTGSLYLSLISLLET------------------------
-----------RDLKGGQTIGLFSYG--SGSVGEFFSGTLVDGFKEQLDVE-RHKSLLNN
RIEVSVDEYEHF----FKRFDQLE---LNHELEKSNADR---------------------
DIFYLKSIDNNIREYHIAE------------
>NZ_ACOS01000095.1|c1|13790-14944|-|ZP_06675037.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDRLSFFIPNLYLDMTELAES
-RGDDPAKYHIGIGQDQMAVNRANEDIITLGANAASKIV--------TEKDRELIDMVIV
GTESGIDHSKASAVIIHHLLKIQSFARSFEVKEACYGGTAALHMAKEYVKNH--PERKVL
VIASDIARYGLASGG-----------EVTQGVGAVAMMITQNPRILSIE-DDSVFLTEDI
YDFWRPDYSEFPV----VDGPLSNSTYIESFQKVWNRHKELSGRG--LEDYQAIAFHIPY
TKMGKKALQSVLDQ-----------TDEENQ--------------------------ERL
MARYEESIRYSRRI----GNLYTGSLYLGLTSLLEN-S----------------------
-----------KSLQPGDRIGLFSYG--SGAVSEFFTGYLEENYQEYLFAQ-SHQEMLDS
RTRIPVDEYETI----F----SET---LPEHGECAEYTSD--------------------
VPFSITKIENDIRYYKI--------------
>NZ_GG670306.1|c1|1236849-1238003|+|ZP_05675899.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDRLSFFIPNLYLDMTDLAES
-RGDDPAKYHIGIGQDQMAVNRANEDIITLGANAASKIV--------TEKDRERIDMVIV
GTESGIDHSKASAVIIHHLLKIQSFARSFEVKEACYGGTAALHMAKEYVKNH--PERKVL
VIASDIARYGLASGG-----------EVTQGVGAVAMMITQNPRILSIE-DDSVFLTEDI
YDFWRPDYSEFPV----VDGPLSNSTYIESFQKVWNRHKGLSGRG--LEDYQAIAFHIPY
TKMGKKALQSVLDQ-----------TDEGNQ--------------------------ERL
LARYDESIRYSRRI----GNLYTGSLYLGLTSLLEN-S----------------------
-----------KSLQPGDRIGLFSYG--SGAVSEFFTGYLEENYQEYLFAQ-SHQEMLDS
RKRISVDEYEMI----F----SES---LPEHGESAEYTSD--------------------
VPFSITKIENDIRYYKI--------------
>NZ_ADMM01000070.1|c1|5871-7025|-|ZP_06625656.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDRLSFFIPNLYLDMTDLAES
-RGDDPAKYHIGIGQDQMAVNRANEDIITLGANAASKIV--------TEKDRERIDMVIV
GTESGIDHSKASAVIIHHLLKIQSFARSFEVKEACYGGTAALHMAKEYVKNH--PERKVL
VIASDIARYGLASGG-----------EVTQGVGAVAMMITQNPRILSIE-DDSVFLTEDI
YDFWRPDYSEFPV----VDGPLSNSTYIESFQKVWNRHKELSGRG--LEDYQAIAFHIPY
TKMGKKALQSVLDQ-----------TDEGNQ--------------------------ERL
LARYEESIRYSRRI----GNLYTGSLYLGLTSLLEN-S----------------------
-----------KSLQPGDCIGLFSYG--SGAVSEFFTGYLEENYQEYLFAQ-SHQEMLDS
RKRISVDEYEMI----F----SES---LPEHGESAEYTSD--------------------
VPFSITKIENDIRYYKI--------------
>NZ_GG688461.1|c1|1326413-1327567|+|ZP_05667405.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKIGIDRLSFFIPNLYLDMTDLAES
-RGDDPAKYHIGIGQDQMAVNRANEDIITLGANAASKIV--------TEKDRERIDMVIV
GTESGIDHSKASAVIIHHLLKIQSFARSFEVKEACYGGTAALHMAKEYVKNH--PERKVL
VIASDIARYGLASGG-----------EVTQGVGAVAMMITQNPRILSIE-DDSVFLTEDI
YDFWRPDYSEFPV----VDGPLSNSTYIESFQKVWNRHKELSGRG--LEDYQAIAFHIPY
TKMGKKALQSVLDQ-----------TDEGNQ--------------------------ERL
LARYEESIRYSRRI----GNLYTGSLYLGLTSLLEN-S----------------------
-----------KSLQPGDRIGLFSYG--SGAVSEFFTGYLEENYQEYLFAQ-SHQEMLDS
RKRISVDEYEMI----F----SES---LPEHGESAEYTSD--------------------
VPFSITKIENDIRYYKI--------------
>NC_002662.1|c1|1613444-1614598|+|NP_267728.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKVGIDKLGFFVPNTFVDMRDLANA
-RNVDPAKFQIGIGQDEMAVNPATQDIITFAANAAASIL--------TEEDKKAIDMIIV
GTESSLDESKASAVVVHDLLGIQPFARSIEMKEACYATTAGLTLARDHVLLN--PDTKVL
VIASDIAKYGLNTGG-----------EPTQGAGSVAMLITADPKILALN-NDNVALTQDI
YDFWRPFGQAYPS----VDGKFSNETYIDAFAKIWKEYSHRTNLK--FEDFAAIAFHTPY
TKMGKKALLPMLES-----------EKPANA--------------------------EEL
MEQFEHGIVYNRRV----GNLYTGSLYLSLISLLEN-S----------------------
-----------DKLSAGQRIGLFSYG--SGTVAEFFSGELVEGYENHLLKI-EHQSMLDA
RTRLSIPEYENM----F----------NQYLDLNHNISFNDE------------------
TDYSVSEVVDNHRKYKKR-------------
>NC_009004.1|c1|898471-899625|-|YP_001032253.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MKVGIDKLGFFVPSTFVDMRDLAEA
-RNVDPAKFQIGIGQDEMAVNPATQDIITFAANAAASIL--------TDEDKETIDMVIV
GTESSLDESKASAVVVHDLLGIQPFARSIEMKEACYATTAGLALARDHVLLN--PEAKVL
VIASDIAKYGLNTGG-----------EPTQGAGSVAMLITANPKIMTLN-NDNVALTQDI
YDFWRPFGQAYPT----VDGKFSNETYIDAFAKIWKEYSRRTSLH--FEDFAALAFHTPY
TKMGKKALLPMLEI-----------EKPANA--------------------------EEL
MEQFERGIVYNRRV----GNLYTGSLYLSLISLLEN-S----------------------
-----------DKLNAGQRIGLFSYG--SGTVAEFFSGELVEGYEKHLLKV-EHQSMLDA
RNRLSIPEYETM----F----------NEYLDLNHNISFSDD------------------
TAYSVSEVVDNHRKYKKI-------------
>NZ_ACCR01000001.1|c1|39001-40158|+|ZP_04442666.1|hydroxymethylglutaryl-CoA_synthase
---------------------------------MTMNVGIDKMSFFVPPYFVDMTDLAVA
-RDVDPNKFLIGIGQDQMAVNPKTQDIVTFATNAAKNIL--------SAEDLDKIDMVIV
GTESGIDESKASAVVLHRLLGIQKFARSFEIKEACYGGTAALQFAVNHIRNH--PESKVL
VVASDIAKYGLASGG-----------EPTQGAGAVAMLVSTDPKIIAFN-DDSLALTQDI
YDFWRPVGHDYPM----VDGPLSTETYIQSFQTVWQEYTKRSQHA--LADFAALSFHIPY
TKMGKKALLAILEG-----------ESEEAQ--------------------------NRI
LAKYEKSIAYSRKA----GNLYTGSLYLGLISLLEN-A----------------------
-----------EDLKAGDLIGLFSYG--SGAVAEFFSGRLVEDYQEQLLKT-KHAEQLAH
RKQLTIEEYETM----F----------SDRLDVDKDAEYEDT------------------
LAYSISSVRNTVREYRS--------------
>NZ_GG670287.1|c1|25700-26854|-|ZP_05649180.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNVGIDKINFFVPPYYLDMVDLAHA
-REVDPNKFTIGIGQDQMAVSKKTHDIVTFAASAAKEIL--------EPEDLQAIDMVIV
GTESGIDESKASAVVLHRLLGVQPFARSFEIKEACYGATAGIQFAKTHIQAN--PESKVL
VIASDIARYGLRSGG-----------EPTQGAGAVAMLLTANPRILTFE-NDNLMLTQDI
YDFWRPLGHAYPM----VDGHLSNQVYIDSFKKVWQAHCERNQAS--ISDYAAISFHIPY
TKMGKKALLAVFAD-----------EVETEQ--------------------------ERV
MARYEESIVYSRRI----GNLYTGSLYLGLISLLEN-S----------------------
-----------SHLSAGDRIGLFSYG--SGAVSEFFSGRLVAGYENQLNKE-AHTQLLDQ
RQKLSIEEYEAI----F----------TDSLEIDQDAAFSDD------------------
LPYSIREIKNTIRYYKES-------------
>NZ_GG670300.1|c2|1945207-1946367|-|ZP_05656192.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNVGIDKINFFVPPYFIDMVDLAHA
-REVDPNKFTIGIGQDQMAVNKKTQDIVTFAMHAAKDIL--------TKEDLQAIDMVIV
GTESGIDESKASAVVLHRLLGIQPFARSFEIKEACYGATAGLQFAKAHVQAN--PQSKVL
VVASDIARYGLASGG-----------EPTQGVGAVAMLISADPAILQLE-NDNLMLTQDI
YDFWRPVGHQYPM----VDGHLSNAVYIDSFKQVWQAHCEKNQRA--AKDYAALSFHIPY
TKMGKKALLAVFAE-----------EDETEQ--------------------------KRL
MARYEESIVYSRRT----GNLYTGSLYLGLISLLEN-S----------------------
-----------SSLQANDRIGLFSYG--SGAVAEFFSGLLVPGYEKQLAQA-AHQALLDD
RQKLTIAEYEAM----F----------NETIDIDQDQSFEDD------------------
LLYSIREIKNTIRYYKEENE-----------
>NZ_GG670388.1|c1|17666-18826|-|ZP_05647277.1|hydroxymethylglutaryl-CoA_synthase
-----------------------------------MNVGIDKINFFVPPYFIDMVDLAHA
-REVDPNKFTIGIGQDQMAVNKKTQDIVTFAMHAAKDIL--------TKEDLQAIDMVIV
GTESGIDESKASAVVLHRLLGIQPFARSFEIKEACYGATAGLQFAKAHVQAN--PQSKVL
VVASDIARYGLASGG-----------EPTQGVGAVAMLISADPAILQLE-NDNLMLTQDI
YDFWRPVGHQYPM----VDGHLSNAVYIDSFKQVWQAHCEKNQRT--AKDYAALSFHIPY
TKMGKKALLAVFAE-----------EDETEQ--------------------------KRL
MARYEESIVYSRRT----GNLYTGSLYLGLISLLEN-S----------------------
-----------SSLQANDRIGLFSYG--SGAVAEFFSGLLVPGYEKQLAQA-AHQALLDD
RQKLTIAEYEAM----F----------NETIDIDQDQSFEDD------------------
LLYSIREIKNTIRYYNEENE-----------
>NC_010628.1|c9|3923372-3924598|+|YP_001866566.1|hydroxymethylglutaryl-coenzyme_A_synthase
----------------------------------MQRVGIEKINLYAGRFCADALELANL
-QGKDLDYVSKQVKVKTRSVIPAYEDTVTLSVNAAKRLL--------SPEDARDIELLIV
ATESAVDFGKPVSTWVHRYCNLPPHCRSFELKHACYGLTAAVKTAAMWLQGGLTPGKKAL
VIGCDYSRPHLDDRD-----------NFIGGGAAIAMLISTDPKVFEIDLHPAGFWTNEI
SDTFRPT-ARVEI----GDNQTSLYSYLDALEASYTHYEKLVGGVDYDKDFQKHIYHTPF
PGMPLQAHRTLLSL-------LEVNDSKIYE--------------------------ENY
QKKVQEGIYFAQQV----GSTYGSSTFLCLLSLLHY-A----------------------
-----------QDLHAGDRISIFAYG--SGCQGEFYRGTVSPGAIEYIRSL-DIDRHLQE
RLPLSLMEYELL---EYAREKYIDAPDYQPKRDSFQNAYDKLYAGQ--------------
ELLVLKQVKNYYRQYEWS-------------
>NC_013440.1|c5|1518516-1519739|+|YP_003265639.1|Hydroxymethylglutaryl-coenzyme_A_synthase_domain
-----------------------------------MDVGIEALNLYVGRLAVDALAIASA
-HGRDPDKMRSQAMIGTRSVAPFWEDAVTLAVNAAKPML--------TAALREDIELLVV
ATESAVDGAKPVATWVHRHCGLPATCRVLDLKHACYGGTGALKLAASWVAGCARPGKKAL
VVCADYTRNRERSHL-----------DAAGGGTSVALVVSAEPRVLSFDPGRAGYFTTEI
ADAFRPT-SRDEI----VDSERSLYSYLDALDGAVDHFEAQFGACE-VDAYQRHIYHAPF
PGMTLHAHRALLNR-------AGVYEDDEIA--------------------------RSF
AAKVEPGLRIARRL----GTAYGASTFVSLLSLLGD-AE---------------------
-----------TPIRAGERLSIFAYG--SGCQGEFYEAVIGPGAHDLAGVA-STASALDE
RESLSVEEFEAIEEARQKYTDERE---FSLEGDALPACYGSAYENK--------------
GLLVLEAVRDFRRSYRWS-------------
>NC_009142.1|c22|5109056-5110279|+|YP_001106764.1|hydroxymethylglutaryl-CoA_synthase
---------------------------------MNVPVGIEAVGAYCGSAYLETEDLFAA
-RGLDAGRIG-NLGLRRKSVAAPGEDVVAMAATAARPLV-------DAVDDKASIRTLVV
ATESPLDLSKAASTHVHQLLGLPRQCRLLEVKQACHGGAAALGLAASVVATE--PGSRAL
VIASDTPVPTRGSYM-----------EPAQGAGAVAVLVGPQPRVVELELGTTGCYGYET
PDFFRPR-PDVDV----MDTDLSLMSYLDCLIGAFGDHAARKPGADFVGSYDLLAMHTPF
PGMVRGAHRTGVRK-------LSGLGRGGEQ--------------------------EDF
GRRVAQSLRFPELV----GNIYSATTLLAMMSAVAG------------------------
-----------APADRPSSMGVFSYG--SGCASEFFACTVLPGAAELVERT-GLEQELAA
RTRLTVADYDVA----VDGAVAAG---FGAEHARVAADDLAAWGAGDR------------
PRAVLSSVENYRREYRWLPAR----------
>NZ_ADGV01000082.1|c1|21320-22555|-|ZP_06401537.1|Hydroxymethylglutaryl-coenzyme_A_synthase_domain
-----------------------------------MNVGIEALNVYCGVASVAVPVLFEG
-RGLDATRLG-NLMMTAKSVALPFEDPVTHAVNAAKPIL-----DAMDEADRDRIELLVT
SSESGLDLSKSIASYVHRHLGLSRRCRMLEVKQACYAATGALQLACGYLAAGLSPGAKAL
VIATDVSLVNENASY----------TEPAMGTGAAAVLLGDDPRVLDVDLGAFGTHSYET
FDSARPG-PTFDV----ADADRSLFAYLDCLTNAYAHYAEKVADVDFATTFGGLAMHTPF
AGIVRAAHRKLARE----------HRMPDAD--------------------------ADF
ARRVAPGLEYPRLV----GNLCSGSVYLALASLIDH------------------------
-----------LRPDEPVRVGMYSYG--SGCAAEFYSGLVDARSTAEVGRM-RIGEHLAG
RCELTFDEYKRI----LADNADCL---VPVADKRIDPGRYAEVLDRVAGA---------R
TLLACTGVRAYHRSYEWIGAGA---------
>NZ_DS570890.1|c1|3398-4645|-|ZP_05014774.1|polyketide_TA_biosynthesis_protein_TaF
--------------------------------MSTARIGVEALNVHAGVAKISARALFDA
-RGLDPDRFD-NLMMDERSVQLPWEDPVTGAVNAAKPLV-----DALSDDDRDSIELLVT
SSESGLDYSKSLASHVHRHLGLSRQCRYMEVKQACYGATGALQLAAGYLRSGLRPGAKAL
IIATDVNPMDEYAKY----------AEPTTGHGAVALLVGDSPGILALTPGAYGLNSFEV
MDTARPA-PDYDL----YNPDLSLLAYLECLSDSFRAYTANVPGTDFADSFDHVVMHTPF
GGMVRAAHRKLMRE-------FAPRAPKAIA--------------------------EDF
ERRVAPSLRYGRVV----GNLCSGAIWLALASLIDHQS----------------------
-----------AERVEGARLGMYSYG--SGCASEFFGATVAPGAKATLGKA-RIAERLAL
RRELTFAEYEQM----LPVTRRIL---VPKAHRDVDDSLQETFLAPFRDH---------G
KQLVLAGVENYIRRYEWR-------------
>NZ_ADGV01000038.1|c1|19108-20349|+|ZP_06399862.1|Hydroxymethylglutaryl-CoA_synthase
--------------------------------MITTAVGIEDLHVYPGRAYVDVPSLFEA
-RGLDPSRLP-NLMMRRRSVSLPCEDQVTHAVNAARPLV-----DALSPEQREAIELVVV
ATESGLDFGKPISTYVHDLLGLPPRCRSFEVKHACYGGTAALQSAAAIIAASPAPDARAL
VIATDIAGVAAAGSY----------FEPSEGAGAVAMLVSRTPDVLRLDLGASGYHTQEV
MDTLRPR-PDVDV----VNSDLSLLAYLTCLERCFAAYRDRVEGADIVTTFDHLVFHIPF
AGMVKGAHRTLLRK-------TKRMAPADID--------------------------RDF
AARVAPSLSYTSEI----GNLYSGSLYLALCSLIDH------------------------
-----------ADFTVARRIGLFSYG--SGCGSEFFSGVVTERAAGRLAAR-PLARAVEE
RRRLTVAEFDEW----SRHTADRA---FGVRDAVLDTGPYRSVLDSHVAG---------R
GLLLLDRIEDFHRVYRWS-------------
>NC_009727.1|c4|1907283-1908521|-|YP_001425244.1|hydroxymethylglutaryl-CoA_synthase_family
---------------------------------MTTKIGIESINAYCGQASLDIKTLFAA
-RDLDLTRFD-NLMMQKKSVNLPCEDSVTSAVNAAKPIL-----DPLSQSERNQIALLIT
ATETGLDFGKSLSTYIYPYLNLSKNCRLFEIKQACYGGTAALQMAAAWVSSQPSSQVKAL
IIATDAARAAARKTY----------AEPSQGTGAVAMLISKNPEILILDNGATGYYGYEI
MDTCRPE-PDLET----GNPDLSLLSYLDCLDNCYRIYCEKVEDINIQTTFNYFAFHTPF
AGMVKGAHRQLLRK----------NGYTDAQ-----------------------FIEADF
QKRVAPSLVYCEQV----GNIYSATVYLALCGIIDN------------------------
-----------TDFINPKRVGIFSYG--SGCCAEFYSGILQPIAKEKLGIL-SIKQSLEN
RYLLDMLAYEKI----IDINQEWF---FGVKNKNVDITPFEEIYTRQFAN---------K
GLLILDKIENYKRYYRWS-------------
>CU459003.1|c4|1209826-1211082|-|CAM75135.1|3-hydroxy-3-methylglutaryl_CoA_synthase
---------------------------------MALAAGIEALNVYGGAACLDVRELCVH
-RGLDMPRFD-NLLMREKTVALPFEDPITFAVNAAKPLV-----DALSVEERARIEMVVT
CTESGIDFGKSISTYVHHHLGLAGNCRLFEIKQACYSGTAGLQMAVNFILSGTSPGAKAL
VVCTDLSRFALADAA---AIQEWAYSEPSSGAGAVALLVSDTPHILRMDAGAYGNHGFEV
MDTCRPG-PDTEA----GDADLSLMAYLDCCERCWKDYARRVEGADFRQSFSYLSFHTPF
GGMVKGAHRALMRK-------LFKAKPDEIE--------------------------ADF
SRRLGPSLTFGQRV----GNTAGGSVFLGLAGLLEN------------------------
-----------AAITEPCRVGLFSYG--SGCCSEFYSGVVSPDSQRRLRAM-GIGADLDR
RYRLSISEYEHL----LRGDHVIR---FGQKDATIAPDTIAGAWSVFQGS----------
GRLVLEAMVGYHRQYRFV-------------
>AY850690.1|c1|6283-7575|+|AAW33975.1|PedP
-----------------------------------MPVGIEAMNLYGGSAFVDVMELAVY
-RKHDLSRFD-NLLMKQKTVALPYEDSVSFAINAAQPLI-----DTLSETEKERIELLIT
CSESGIDFGKSISTYIHHYLGLNRNCRLFELKQACYSGTAGLQMAVNFIVSKVSPGAKAL
VIASDLSRFLVTRDEEGELTMDWDFFEPSGGAGAIAMLVSEKPDIFELDIGANGYYTYEV
MDTCRPI-ADSEA----GNADLSLLSYLDCCDQSFKEYKKRVFKVDYCDTFQYLCFHTPF
GGMVKGAHRNMMRK-------YSDLSREAIE--------------------------ADF
QQRVQPGLTYCQRV----GNIMGGTIMLSLASTIDN------------------------
-----------AIMRNTCRVGCFSYG--SGCCSEFYSGVVSPSGQAKLRDW-ALGKHLDS
RHRLTMEQYEIV----LQRSELVK---FGTRNVVLSNDLIPGAWKTITRNVRENKDIDIG
KRIFLSEIKEFHRHYEWIE------------
>NZ_ADBX01000002.1|c1|106031-107293|-|ZP_06190158.1|hypothetical_protein
----------------------------------MISVGIEAINAFCGSSYINVRDLAQH
-RQLDISRFD-NLLMKQKTVSLPCEDPVSFAVNAAKPIL-----DALSDAEKNSIELLIT
CTESGIDFGKSLSTYVHHYLGLKRNCRLFELKTACYSGVAGLQMAVNTILSQTSPGSKAL
VIATDMTRFILEEENAATTSQDWSFAEPSGGSGAVAMLVSDSPHVFQIDVGANGYYGYEV
MDTCRPI-PDMET----GDSDLSLLAYLECCEKAYQEYEKRTADIDYVNTFGYLAFHTPF
GGMVKGAHRNMMRK-------LVRAAPQDIE--------------------------ADF
ARRVIPGLNYCQRV----GNIMGATLALSLLSTLAN------------------------
-----------ADIHSAQRIGCFSYG--SGCCSEFFSGVVTPESAQRVRQM-DIGAHLDN
RRELTMAEYDAL----LYSNQRVS---FGTKTVELDLSLFPQIHAGSRAP----------
HRLVLRRINQFHREYEWV-------------
>FJ823461.1|c1|64017-65279|+|ADA82596.1|3-hydroxy-3-methylglutaryl-CoA_synthase_family
----------------------------------MMPVGIEAINVFGGSACLDVERLAVH
-RQMDMDRFA-NLLMKEKTVALPNEDPVSFAINAAKPVL-----DGLSPDERAKIEMVIT
CTESAFDFGKSMSTYVQDLLELPRRCRLFELKNACYSGTAGLQMAVNFVLSQTSPGAKAL
VVASDLSRFLMEEGG-DALTEDWSFAEPSSGAGAVAMLVSDTPYIFQVDVGANGYYGFEV
MDTCRPS-ADTEA----GDADLSLLSYLECCEQAFLAYQERVEGADYRATFGYLAFHTPF
GGMVKGAHRRMMRK-------FGKVAAKDIE--------------------------ADF
VRRIVPGLTHCQRL----GNIMGATLPLALVSTIEH------------------------
-----------AEIEEATRIGCFSYG--SGCCSEFFSGVATVDGQARVRSL-GLKDQFDQ
RYALSMEEYETL----LRESGVVK---FGTRNASPYAGAMSGACKGTSAG----------
PRLYLKAIREFHREYEWIA------------
>AY907538.1|c1|18031-19353|-|AAY00042.1|HMG-CoA-synthase-like_protein
--------------MAVRRDRPEGARSGDRRNENMMPVGIEAINVFGGSACLDVERLAVH
-RQMDMDRFA-NLLMKEKTVALPNEDPVSFAINAAKPVL-----DGLSPDERAKIEMVIT
CTESAFDFGKSMSTYVQDLLELPRRCRLFELKNACYSGTAGLQMAVNFVLSQTSPGAKAL
VVASDLSRFLMEEGG-DALTEDWSFAEPSSGAGAVAMLVSDTPYIFQVDVGANGYYGFEV
MDTCRPS-ADTEA----GDADLSLLSYLECCQQAFLAYQDRVEGADYRATFGYLAFHTPF
GGMVKGAHRTMMRK-------FGKVAAKDIE--------------------------ADF
VRRVVPGLTHCQRL----GNIMGATLPLALVSTIEH------------------------
-----------AEIEEATRIGCFSYG--SGCCSEFFSGVATVDGQARVRSL-GLKDQFDQ
RYALSMEEYETL----LRESGVVK---FGTRNATPHAGTISGVCKGTSAG----------
PRLYLKAIREFHREYEWIA------------
>NC_008095.1|c10|4807103-4808365|-|YP_632128.1|polyketide_TA_biosynthesis_protein_TaC
----------------------------------MGPVGIEAMNAYCGIARLDVLQLATH
-RGLDTSRFA-NLLMEEKTVPLPYEDPVTYGVNAARPIL-----DQLTAAERDSIELLVA
CTESSFDFGKAMSTYLHQHLGLSRNCRLIELKSACYSGVAGLQMAVNFILSGVSPGAKAL
VVASDLSRFSIAEGG-DASTEDWSFAEPSSGAGAVAMLVSDTPRVFRVDVGANGYYGYEV
MDTCRPV-ADSEA----GDADLSLLSYLDCCENAFREYTRRVPAANYAESFGYLAFHTPF
GGMVKGAHRTMMRK-------FSGKNRGDIE--------------------------ADF
QRRVAPGLTYCQRV----GNIMGATMALSLLGTIDH------------------------
-----------GDFATAKRIGCFSYG--SGCSSEFFSGVVTEEGQQRQRAL-GLGEALGR
RQQLSMPDYDAL----LKGNGLVR---FGTRNAELDFGVVGSIRPGGWGR----------
PLLFLSAIRDFHRDYQWIS------------
>NZ_ABBM01000954.1|c1|4682-5935|+|ZP_02467737.1|putative_hydroxymethylglutaryl-coenzyme_A
------------------------------------MVGIEAMNLYAGVARLDVTALARH
-RGLDMRRFE-NLLMKEKTVALPYEDPVTFAVNAAKPIV-----DALTQQERDQIRMLIT
CTESGFDFSKSMSTYCHDLLGLGRHCRMFEIKGACYSGTAGLETAINFVLSRTRPGGKAL
VLATDVSRFMVEDRG-DALSADWSFSEPSGGSGAVAMLVSDQPHVFQIDAGANGCYGYEV
MDTCRPA-ADADA----GNADLSLLSYLTCCENAFLDYRERVADADFAATFSYLAFHTPF
GGMVKGAHRTMMRK-------LAMAKPPAIE--------------------------ADF
ERRVAPGLAYCQRV----GNIMGATAALSLASTIRH------------------------
-----------GDFSEPRRVGVFSYG--SGCCSEFFSGVATQDGARRLAEL-GIGEHLDR
RYNMTLDEYETV----LARSREIR---FGTRDLDADATLLRQARGVHRR-----------
PTLFLKSIRDFHREYEWVS------------
>NZ_CH899679.1|c1|229992-231161|-|ZP_04880834.1|putative_polyketide_biosynthesis_protein_pksG,
----------------------------------MTAVGIEALNVYAGVASLDVSRLAEH
-RKLDMARFQ-NLLMREKSVALPYEDPITYGVNAAKPIV-----DALTPDERDRIEMLIT
CTESAFDFGKSMSTYFHHHLGLKRNCRLFEVKNACYSGVAGLQTAINFILAQVSPGAKAL
VIATDLSRFIVEEGG-EALSADWSFAEPSSGAGAVAMLVSDTPHVFRIDVGANGCYGYEV
MDTCRPT-TDSEA----GNSDLSLLSYLDCCENAFLEYQKRVCDVDYASTFGFLAFHTPF
GGMVKGAHRNLMRK-------ASRCSTQEIE--------------------------QDF
QRRAGPGLVYCQRL----GNIMGATAMLSVASTIDN------------------------
-----------GEYRAPQRVGVFSYG--SGCCSEFFSGIVDEEGQRRLRGM-RIGEQLDR
RYALSIDEYEHV----L---KERF---IAENRGDLENDCVT-------------------
-------------------------------
>NZ_ACCE01000001.1|c3|484745-486004|+|ZP_03450573.1|putative_polyketide_biosynthesis_protein_pksG
----------------------------------MTAVGIEALNVYAGVASLDVSRLAEH
-RKLDMARFQ-NLLMREKSVALPYEDPITYGVNAAKPIV-----DALTPDERDRIEMLIT
CTESAFDFGKSMSTYFHHHLGLKRNCRLFEVKNACYSGVAGLQTAINFILAQVSPGAKAL
VIATDLSRFIVEEGG-EALSADWSFAEPSSGAGAVAMLVSDTPHVFRIDVGANGYYGYEV
MDTCRPT-TDSEA----GNSDLSLLSYLDCCENAFLEYQKRVCDVDYASTFGFLAFHTPF
GGMVKGAHRNLMRK-------ASRCSTQEIE--------------------------QDF
QRRAGPGLVYCQRL----GNIMGATAMLSVASTIDN------------------------
-----------GEYRAPQRVGVFSYG--SGCCSEFFSGIVDEEGQRRLRGM-RIGEQLDR
RYALSIDEYEHV----LKESRVVR---FGTRNAKIDDGFIPAARRAHGR-----------
ETLFLSRINEYHREYEWIC------------
>NC_007435.1|c13|3143212-3144471|-|YP_337763.1|putative_hydroxymethylglutaryl-coenzyme_A
----------------------------------MTAVGIEALNVYAGVASLDVSRLAEH
-RKLDMARFQ-NLLMREKSVALPYEDPITYGVNAAKPIV-----DALTPDERDRIEMLIT
CTESAFDFGKSMSTYFHHHLGLKRNCRLFEVKNACYSGVAGLQTAINFILAQVSPGAKAL
VIATDLSRFIVEEGG-EALSADWSFAEPSSGAGAVAMLVSDTPHVFRIDVGANGYYGYEV
MDTCRPT-TDSEA----GNSDLSLLSYLDCCENAFLEYQKRVCDVDYASTFGFLAFHTPF
GGMVKGAHRNLMRK-------ASRCSTQEIE--------------------------QDF
QRRAGPGLVYCQRL----GNIMGATAMLSVASTIDN------------------------
-----------GEYRAPQRVGVFSYG--SGCCSEFFSGIVDEEGQRRLRGM-RIGEQLDR
RYALSIDEYEHV----LKESRVVR---FGTRNAKIDDGFIPAARRAHSR-----------
ETLFLSRINEYHREYEWIC------------
>EF032014.1|c1|1395-2657|-|ABK51297.1|BryR
----------------------------------MRYIGIESMNAFGGTAFLDVMKLAQH
-RQLEMSRFD-NLLMHQKSVALPYEDPITFGVNAAKPII-----DGLSDVEKNNIELLIT
CSESGIDFSKSMSTYIHKYLGLNRSCRLFEIKQACYSGTAGFQMAINFILSRTSPGAKAL
IVATDISRFIIDKNN-SEQVEDWSYAEPSNGAGAVALLISESPHIYQVDIGANGYYGYEV
MDTCRPE-ADGDA----GDADLSLLSYLDCCEHAFLEYQKRVEDVDYRHSFDYLAFHTPF
GGMVKGAHRTMMRK-------IAKAQPHEIE--------------------------EDF
QRRVVPGLNYCQRV----GNIMGATIFLSLASTICN------------------------
-----------GHYLSPKRLGCFSYG--SGCCSEFYSGMVTQEGAQTLKKF-NIEKELNE
RYSLSMSEYDNL----LIHSQCVK---FGTRNTKLDLDIISGAKVSMNGK----------
QRLVLKEIKEFHREYQWIN------------
>AY522504.1|c1|19453-20712|+|AAS98779.1|JamH
----------------------------------MQSVGIEALSVYGGAAQLDVRKLVQA
-RQLDISRFD-NLMMKEKAVSLPYEDPVSYAVNAAKPII-----DRLSNADKQRIEMVIT
CSESGIDFGKSMSTYIQEYLGLSRNCRMFELKQACYSGTAGLQMAINLILSQTFPGAKAL
VIATDISRFLVAEGG-EALSEDWSFAEPSSGAGAVALLVSDTPYIFQVDVGCNGYYGYEV
MDTCRPN-PDSEA----GDADLSLLSYLDCCENAYRHYQNRVEGVDYQESFDYLSFHTPF
GGMVKGAHRSMMRR-------LKRAKPADIE--------------------------ADF
QRRVMPGLVYCQQV----GNIMGATLFLSLASTIDN------------------------
-----------GDFSTPRRIGMFSYG--SGCCSEFYSGVVTPEGKQIQAQQ-GISSQLAD
RYSLSMEEYEQL----LYHSSAVA---FGTRNVTLDYQLFPGVWKQIAGK----------
GRLVLKAIKEFHREYEWV-------------
>NC_011884.1|c1|2838841-2840100|-|YP_002483588.1|Hydroxymethylglutaryl-coenzyme_A_synthase_domain
----------------------------------MIPVGIEALNVYAGAAKLDIQRLAQV
-RNLDAHRFE-NLLMKEKTVALPYEDAVSFGINAAKPII-----DQLSESERQSIELLIA
CTESSLDFGKSISTYMHDYLGLSRHCRQFELKQACYAGTAGLQMAANFILSQTSPGAKAL
VIATDISRFKVAEGG-STLSEDWSFAEPSSGAGAVAMLVSDRPVLLKLDIGCNGYYGYEV
MDTCRPI-PDSEA----GDADLSLLSYLDCCEQTYLHYESKVEDVDYQESFHYLAFHTPF
GGMVKGAHRTMMRK-------LKQAKPTEIE--------------------------ADF
VERVLPGLLYCQRV----GNIMGATLYLALASIIDH------------------------
-----------HQWEAPRRIGLFSYG--SGCCSEFFSGVVSPTAHAQQQSY-AIAKHLNA
RYPLSIEEYEQI----LRSNQAGG---FGTRNMCSDYQVVPGVWQQIQGQ----------
NRLILKSIQEFHREYEWV-------------
>NC_007650.1|c4|1997172-1998428|-|YP_439864.1|polyketide_biosynthesis_protein
-----------------------------------MPVGIEAMNVYGGSAALDVSELARH
-RKLDMSRFA-NLLMREKAVALPFEDPITFGVNAAKPIV-----DALSDAERERIEMLIT
CTESGIDFGKSISTYLHHHLGLNRNCRLFEVKQACYSGTAGFQTAVNFILSQTSPGAKAL
VVATDISRFMVVEGG-DAISEDWSFAEPSAGAGAVAMLVSDAPAVFQLDVGAHGYYGYEV
MDTCRPV-PDSEA----GDSDLSLMSYLECCERAWGEYASRVTGADYRNTFQYLAFHTPF
GGMVKGAHRSMMRK-------VVRARADEAE--------------------------ADF
VARVEPGLAYCQRV----ANVMGATVFLSLASTIDH------------------------
-----------GDFSTPRRIGLFSYG--SGCCSEFFSGVVTQEGQRRLAAM-RIGQQLDA
RYRLSLAEYDAL----LLGSGAVR---FGTRNVELGASLLPGPRAMLAGK----------
NRLVLARIREFHREYVWS-------------
>AJ634062.2|c1|67588-68835|+|CAG23985.1|3-hydroxy-3-methylglutaryl_coenzyme_A
-----------------------------------MNVGIEAMNVFGGTAYVDVMELAEH
-RNLDKKRFE-NLLMKEKVVALPFEDPITFAVNAAKPII-----DSLSEEERNQIEMVIT
CTESGIDFGKSISTYVHDYLQLKRNCRLFEVKQACYSLTAGFQMGVNFILSQTSPGAKAL
IIGTDISRFLVAEGG-DALTEEWSYAEPSAGAGAVALLVSSTPHVFLLDQGASGYYGYEV
MDTCRPI-PDSEA----GDADLSLMSYLDCCEKSFQEYRKRVSGADYKNTFQYLSFHTPF
GGMVKGAHRTMMRK-------LAKAKPQDIE--------------------------ADF
QQRVLPGVQYCQRV----GNIMGATVFLSLASTIDN------------------------
-----------GSFETPKRVGCFSYG--SGCCSEFYSGVVMPQSRTRQNQF-QISRHLDE
RVRLSMADYDRL----LQDSGIVK---FGTRNAAPAADILNAHQGK--------------
TRLVLTEIKEFHRKYEWTT------------
>GU479979.1|c1|47898-49160|+|ADD82944.1|BatC
----------------------------------MSLVGIEAMNVFGGTTYLDVAELARH
-RQLDSARFA-NLLMKEKAVALPYEDPVTFGVNAAKPII-----DAMSPAERDRIELLIT
CTESGIDFGKSMSTYIHHYLGLNRNCRLFELKQACYSGTAGFQMAINFILSQVSPGAKAL
IVATDISRFLASEAG-SELTEDWSFAEPSAGAGAVALLVSDQPHVFQVDVGANGYYGYEV
MDTCRPM-PDSEA----GDADLSLLSYLDCCENAYLEYTKRVTNAHYRDSFQYLTFHTPF
GGMVKGAHRTMMRK-------LLQAKTAEIE--------------------------EDF
QRRVMSGMTYCQRV----GNIMGATSFLSLASTIDN------------------------
-----------GQFTAPRRIGCFSYG--SGCCSEFYSGVVTPDSQVRQRRF-AIKEHLNG
RYRLSMAEYESI----IQASNAVK---FGSRNVELDKSFIGEAYESCRGK----------
GQLFLREIKEFHRQYEWLS------------
>NC_009725.1|c4|1705925-1707187|+|YP_001421289.1|BaeG
----------------------------------MAAAGIEAINVFGGTAYLDVMQLAEY
-RNLDPARFE-NLLMKEKAVALPYEDPVTFGVNAAKPII-----DRLTEAEKDRIELLIT
CSESGIDFGKSLSTYIHDHLGLNRNCRLFELKQACYSGTAGLQMALNFILSQTSPGAKAL
VVATDISRFLIAEGG-DALSEDWSYAEPSAGAGAVALLIGENPIVFQADAGANGYYGYEV
MDTCRPI-PDSEA----GDADLSLMSYLDCCEQTFREYKNRVPGADYKETFHYLAFHTPF
GGMVKGAHRTMMRK-------LAKAKNAEIE--------------------------QDF
QTRVEPGLRYCQRV----GNIMGAASLLALASTIDQ------------------------
-----------GGFDTSKRIGCFSYG--SGCCSEFYSGVVTPEGQARQHSF-KIEEHLNN
RYRLSMEEYEEL----FKGSGLVK---FGTRNVKLDVNMIPNILDHHTGS----------
PRLYLEEITEFHRKYRWIS------------
>NC_000964.3|c3|1789943-1791205|+|NP_389595.2|acetyl-S-AcpK_beta-ketothioester_polyketide
----------------------------------MVSAGIEAMNVFGGTAYLDVMELAKY
-RHLDTARFE-NLLMKEKAVALPYEDPVTFGVNAAKPII-----DALSEAEKDRIELLIT
CSESGIDFGKSLSTYIHEYLGLNRNCRLFEVKQACYSGTAGFQMAVNFILSQTSPGAKAL
VIASDISRFLIAEGG-DALSEDWSYAEPSAGAGAVAVLVGENPEVFQIDPGANGYYGYEV
MDTCRPI-PDSEA----GDSDLSLMSYLDCCEQTFLEYQKRVPGANYQDTFQYLAYHTPF
GGMVKGAHRTMMRK-------VAKVKTSGIE--------------------------TDF
LTRVKPGLNYCQRV----GNIMGAALFLALASTIDQ------------------------
-----------GRFDTPKRIGCFSYG--SGCCSEFYSGITTPQGQERQRTF-GIEKHLDR
RYQLSMEEYELL----FKGSGMVR---FGTRNVKLDFEMIPGIMQSTQEK----------
PRLFLEEISEFHRKYRWIS------------
>U11039.1|c1|2270-3307|+|AAA85140.1|unknown
------------------------------------------------------------
--------------------------------------------------------MLIT
CSESGIDFGKSLSTYIHEYLGLNRNCRLFEVKQACYSGTAGFQMAVNFILSQTSPGAKAL
VIASDISRFLIAEGG-DALSEDWSYAEPSAGAGAVAVLVGENPEVFQIDPGANGYYGYEV
MDTCRPI-PDSEA----GDSDLSLMSYLDCCEQTFLEYQKRVPGANYQDTFQYLAYHTPF
GGMVKGAHRTMMRK-------VAKVKTSGIE--------------------------TDF
LTRVKPGLNYCQRV----GNIMGAALFLALASTIDQ------------------------
-----------GRFDTPKRIGCFSYG--SGCCSEFYSGITTPQGQERQRTF-GIEKHLDR
RYQLSMEEYELL----FKGSGMVR---FGTRNVKLDFEMIPGIMQSTQEK----------
PRLFLEEISEFHRKYRWIS------------
